TreeWAS – Variant ID: rs76413021

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D64.9 Anaemia, unspecified	0.027	0.973	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.022	0.978	0.000
D64 Other anaemias	0.018	0.982	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.017	0.983	0.000
Z88.5 Personal history of allergy to narcotic agent	0.015	0.985	0.000
Z88.2 Personal history of allergy to sulphonamides	0.014	0.986	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.014	0.986	0.000
D64.8 Other specified anaemias	0.013	0.987	0.000
D64.4 Congenital dyserythropoietic anaemia	0.013	0.987	0.000
D64.3 Other sideroblastic anaemias	0.013	0.987	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.013	0.987	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.013	0.987	0.000
D64.0 Hereditary sideroblastic anaemia	0.013	0.987	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.013	0.987	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.013	0.987	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.013	0.987	0.000
Z88.6 Personal history of allergy to analgesic agent	0.012	0.988	0.000
D60-D64 Aplastic and other anaemias	0.012	0.988	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.012	0.988	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.010	0.990	0.000
D61 Other aplastic anaemias	0.009	0.990	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.009	0.991	0.000
D62 Acute posthaemorrhagic anaemia	0.009	0.991	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.008	0.992	0.000
D61.9 Aplastic anaemia, unspecified	0.007	0.993	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.007	0.993	0.000
I77.1 Stricture of artery	0.007	0.993	0.000
D61.8 Other specified aplastic anaemias	0.007	0.993	0.000
D61.3 Idiopathic aplastic anaemia	0.007	0.993	0.000
D61.2 Aplastic anaemia due to other external agents	0.007	0.993	0.000
D61.1 Drug-induced aplastic anaemia	0.007	0.993	0.000
D61.0 Constitutional aplastic anaemia	0.007	0.993	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.007	0.993	0.000
D60.8 Other acquired pure red cell aplasias	0.007	0.993	0.000
D60.1 Transient acquired pure red cell aplasia	0.007	0.993	0.000
D60.0 Chronic acquired pure red cell aplasia	0.007	0.993	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.007	0.993	0.000
I77 Other disorders of arteries and arterioles	0.007	0.993	0.000
D63.0 Anaemia in neoplastic disease	0.006	0.993	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.006	0.994	0.000
I84.2 Internal haemorrhoids without complication	0.006	0.994	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.006	0.994	0.000
I73 Other peripheral vascular diseases	0.005	0.995	0.000
L40.9 Psoriasis, unspecified	0.005	0.995	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.005	0.995	0.000
S00-S09 Injuries to the head	0.005	0.995	0.000
Chapter IX Diseases of the circulatory system	0.005	0.995	0.000
I21 Acute myocardial infarction	0.005	0.995	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.005	0.995	0.000
I77.8 Other specified disorders of arteries and arterioles	0.005	0.995	0.000
I77.6 Arteritis, unspecified	0.005	0.995	0.000
I77.5 Necrosis of artery	0.005	0.995	0.000
I77.4 Coeliac artery compression syndrome	0.005	0.995	0.000
I77.3 Arterial fibromuscular dysplasia	0.005	0.995	0.000
I77.2 Rupture of artery	0.005	0.995	0.000
I77.0 Arteriovenous fistula, acquired	0.005	0.995	0.000
I84 Haemorrhoids	0.005	0.995	0.000
S01 Open wound of head	0.005	0.995	0.000
D80-D89 Certain disorders involving the immune mechanism	0.005	0.995	0.000
D55-D59 Haemolytic anaemias	0.005	0.995	0.000
D50-D53 Nutritional anaemias	0.005	0.995	0.000
I84.8 Unspecified haemorrhoids with other complications	0.005	0.995	0.000
Chapter XX External causes of morbidity and mortality	0.005	0.995	0.000
M22.4 Chondromalacia patellae	0.005	0.995	0.000
N18.3 Chronic kidney disease, stage 3	0.005	0.995	0.000
E10-E14 Diabetes mellitus	0.005	0.995	0.000
I73.9 Peripheral vascular disease, unspecified	0.005	0.995	0.000
M20-M25 Other joint disorders	0.005	0.995	0.000
L40 Psoriasis	0.005	0.995	0.000
M22 Disorders of patella	0.005	0.995	0.000
I84.4 External haemorrhoids with other complications	0.005	0.995	0.000
I74 Arterial embolism and thrombosis	0.005	0.995	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.005	0.995	0.000
I20-I25 Ischaemic heart diseases	0.005	0.995	0.000
I70 Atherosclerosis	0.004	0.995	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.995	0.000
S06 Intracranial injury	0.004	0.995	0.000
E10.3 With ophthalmic complications	0.005	0.995	0.000
# Top node	0.005	0.995	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.005	0.995	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.004	0.995	0.000
I72 Other aneurysm	0.004	0.995	0.000
W00-W19 Falls	0.004	0.995	0.000
I73.0 Raynaud's syndrome	0.004	0.995	0.000
N18 Chronic renal failure	0.005	0.995	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.995	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.004	0.995	0.000
E10 Insulin-dependent diabetes mellitus	0.004	0.996	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.004	0.996	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.004	0.996	0.000
S01.5 Open wound of lip and oral cavity	0.004	0.996	0.000
M23 Internal derangement of knee	0.004	0.996	0.000
S01.8 Open wound of other parts of head	0.004	0.996	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.004	0.996	0.000
I21.4 Acute subendocardial myocardial infarction	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
I78 Diseases of capillaries	0.004	0.996	0.000
I21.9 Acute myocardial infarction, unspecified	0.004	0.996	0.000
M23.3 Other meniscus derangements	0.004	0.996	0.000
S80-S89 Injuries to the knee and lower leg	0.004	0.996	0.000
T66-T78 Other and unspecified effects of external causes	0.004	0.996	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
E87.6 Hypokalaemia	0.004	0.996	0.000
S02 Fracture of skull and facial bones	0.004	0.996	0.000
T51 Toxic effect of alcohol	0.004	0.996	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.004	0.996	0.000
W20-W49 Exposure to inanimate mechanical forces	0.004	0.996	0.000
S70-S79 Injuries to the hip and thigh	0.004	0.996	0.000
S40-S49 Injuries to the shoulder and upper arm	0.004	0.996	0.000
I73.8 Other specified peripheral vascular diseases	0.004	0.996	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.004	0.996	0.000
I84.3 External thrombosed haemorrhoids	0.004	0.996	0.000
I05-I09 Chronic rheumatic heart diseases	0.004	0.996	0.000
N18.4 Chronic kidney disease, stage 4	0.004	0.996	0.000
S01.2 Open wound of nose	0.004	0.996	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.004	0.996	0.000
S01.1 Open wound of eyelid and periocular area	0.004	0.996	0.000
W18 Other fall on same level	0.004	0.996	0.000
X60-X84 Intentional self-harm	0.004	0.996	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.004	0.996	0.000
E13 Other specified diabetes mellitus	0.004	0.996	0.000
T79-T79 Certain early complications of trauma	0.004	0.996	0.000
T33-T35 Frostbite	0.004	0.996	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.004	0.996	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.004	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.004	0.996	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.004	0.996	0.000
T00-T07 Injuries involving multiple body regions	0.004	0.996	0.000
S10-S19 Injuries to the neck	0.004	0.996	0.000
M23.4 Loose body in knee	0.004	0.996	0.000
E50-E64 Other nutritional deficiencies	0.004	0.996	0.000
L40-L45 Papulosquamous disorders	0.004	0.996	0.000
V20-V29 Motorcycle rider injured in transport accident	0.004	0.996	0.000
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
S08 Traumatic amputation of part of head	0.004	0.996	0.000
S07 Crushing injury of head	0.004	0.996	0.000
S05 Injury of eye and orbit	0.004	0.996	0.000
S04 Injury of cranial nerves	0.004	0.996	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.004	0.996	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
Chapter VII Diseases of the eye and adnexa	0.004	0.996	0.000
E28 Ovarian dysfunction	0.004	0.996	0.000
M35 Other systemic involvement of connective tissue	0.004	0.996	0.000
M21 Other acquired deformities of limbs	0.004	0.996	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.004	0.996	0.000
E11 Non-insulin-dependent diabetes mellitus	0.004	0.996	0.000
S00 Superficial injury of head	0.004	0.996	0.000
I84.1 Internal haemorrhoids with other complications	0.004	0.996	0.000
L40.5 Arthropathic psoriasis	0.004	0.996	0.000
M15-M19 Arthrosis	0.004	0.996	0.000
N43.3 Hydrocele, unspecified	0.004	0.996	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.004	0.996	0.000
S20-S29 Injuries to the thorax	0.004	0.996	0.000
T51.0 Ethanol	0.004	0.996	0.000
M24 Other specific joint derangements	0.004	0.996	0.000
I00-I02 Acute rheumatic fever	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
I20.0 Unstable angina	0.004	0.996	0.000
Z88.0 Personal history of allergy to penicillin	0.004	0.996	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.004	0.996	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.004	0.996	0.000
S01.0 Open wound of scalp	0.004	0.996	0.000
E14 Unspecified diabetes mellitus	0.004	0.996	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
I84.0 Internal thrombosed haemorrhoids	0.004	0.996	0.000
S01.7 Multiple open wounds of head	0.004	0.996	0.000
S01.4 Open wound of cheek and temporomandibular area	0.004	0.996	0.000
S01.3 Open wound of ear	0.004	0.996	0.000
D53 Other nutritional anaemias	0.004	0.996	0.000
D52 Folate deficiency anaemia	0.004	0.996	0.000
D59 Acquired haemolytic anaemia	0.004	0.996	0.000
D58 Other hereditary haemolytic anaemias	0.004	0.996	0.000
D57 Sickle-cell disorders	0.004	0.996	0.000
D56 Thalassaemia	0.004	0.996	0.000
D55 Anaemia due to enzyme disorders	0.004	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D86 Sarcoidosis	0.004	0.996	0.000
D84 Other immunodeficiencies	0.004	0.996	0.000
D83 Common variable immunodeficiency	0.004	0.996	0.000
D82 Immunodeficiency associated with other major defects	0.004	0.996	0.000
D81 Combined immunodeficiencies	0.004	0.996	0.000
D80 Immunodeficiency with predominantly antibody defects	0.004	0.996	0.000
C18 Malignant neoplasm of colon	0.004	0.996	0.000
M23.49 Loose body in knee-Unspec lig/men	0.004	0.996	0.000
W18.5 Trade and service area	0.004	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
S06.2 Diffuse brain injury	0.004	0.996	0.000
V10-V19 Pedal cyclist injured in transport accident	0.004	0.996	0.000
Y57 Other and unspecified drugs and medicaments	0.004	0.996	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.004	0.996	0.000
Y35-Y36 Legal intervention and operations of war	0.004	0.996	0.000
Y10-Y34 Event of undetermined intent	0.004	0.996	0.000
Y00-Y09 Assault	0.004	0.996	0.000
X85-X99 Assault	0.004	0.996	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.004	0.996	0.000
X50-X57 Overexertion, travel and privation	0.004	0.996	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.004	0.996	0.000
X30-X39 Exposure to forces of nature	0.004	0.996	0.000
X20-X29 Contact with venomous animals and plants	0.004	0.996	0.000
X10-X19 Contact with heat and hot substances	0.004	0.996	0.000
X00-X09 Exposure to smoke, fire and flames	0.004	0.996	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.004	0.996	0.000
W75-W84 Other accidental threats to breathing	0.004	0.996	0.000
W65-W74 Accidental drowning and submersion	0.004	0.996	0.000
W50-W64 Exposure to animate mechanical forces	0.004	0.996	0.000
V98-V99 Other and unspecified transport accidents	0.004	0.996	0.000
V95-V97 Air and space transport accidents	0.004	0.996	0.000
V90-V94 Water transport accidents	0.004	0.996	0.000
V80-V89 Other land transport accidents	0.004	0.996	0.000
V70-V79 Bus occupant injured in transport accident	0.004	0.996	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.004	0.996	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.004	0.996	0.000
V40-V49 Car occupant injured in transport accident	0.004	0.996	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.004	0.996	0.000
V01-V09 Pedestrian injured in transport accident	0.004	0.996	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.004	0.996	0.000
S06.5 Traumatic subdural haemorrhage	0.004	0.996	0.000
T93 Sequelae of injuries of lower limb	0.004	0.996	0.000
C18.9 Colon, unspecified	0.004	0.996	0.000
I71 Aortic aneurysm and dissection	0.003	0.996	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.004	0.996	0.000
W07 Fall involving chair	0.004	0.996	0.000
S92 Fracture of foot, except ankle	0.004	0.996	0.000
T90 Sequelae of injuries of head	0.004	0.996	0.000
I86 Varicose veins of other sites	0.004	0.996	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.996	0.004
Y83.4 Other reconstructive surgery	0.004	0.996	0.000
E12 Malnutrition-related diabetes mellitus	0.004	0.996	0.000
I85 Oesophageal varices	0.004	0.996	0.000
S70 Superficial injury of hip and thigh	0.004	0.996	0.000
E14.3 With ophthalmic complications	0.004	0.996	0.000
N18.2 Chronic kidney disease, stage 2	0.004	0.996	0.000
I20 Angina pectoris	0.004	0.996	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
N17-N19 Renal failure	0.004	0.996	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.004	0.996	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.003	0.996	0.000
I22 Subsequent myocardial infarction	0.004	0.996	0.000
I82 Other venous embolism and thrombosis	0.004	0.996	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.004	0.996	0.000
M34 Systemic sclerosis	0.004	0.996	0.000
M33 Dermatopolymyositis	0.004	0.996	0.000
M32 Systemic lupus erythematosus	0.004	0.996	0.000
M30 Polyarteritis nodosa and related conditions	0.004	0.996	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
I84.5 External haemorrhoids without complication	0.004	0.996	0.000
L40.8 Other psoriasis	0.003	0.996	0.000
L40.4 Guttate psoriasis	0.003	0.996	0.000
L40.3 Pustulosis palmaris et plantaris	0.003	0.996	0.000
L40.2 Acrodermatitis continua	0.003	0.996	0.000
L40.1 Generalised pustular psoriasis	0.003	0.996	0.000
L40.0 Psoriasis vulgaris	0.003	0.996	0.000
M22.1 Recurrent subluxation of patella	0.003	0.996	0.000
M22.9 Disorder of patella, unspecified	0.003	0.996	0.000
M22.8 Other disorders of patella	0.003	0.996	0.000
M22.3 Other derangements of patella	0.003	0.996	0.000
M22.2 Patellofemoral disorders	0.003	0.996	0.000
M22.0 Recurrent dislocation of patella	0.003	0.996	0.000
C15-C26 Malignant neoplasms of digestive organs	0.004	0.996	0.000
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
D00-D09 In situ neoplasms	0.004	0.996	0.000
M65-M68 Disorders of synovium and tendon	0.004	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.003	0.996	0.000
I74.8 Embolism and thrombosis of other arteries	0.003	0.996	0.000
I74.5 Embolism and thrombosis of iliac artery	0.003	0.996	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.003	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.003	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.003	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.003	0.996	0.000
E11.2 With renal complications	0.004	0.996	0.000
E55 Vitamin D deficiency	0.003	0.996	0.000
I88 Nonspecific lymphadenitis	0.003	0.996	0.000
I87 Other disorders of veins	0.003	0.996	0.000
I81 Portal vein thrombosis	0.003	0.996	0.000
S01.9 Open wound of head, part unspecified	0.003	0.996	0.000
I23 Certain current complications following acute myocardial infarction	0.003	0.996	0.000
M40-M43 Deforming dorsopathies	0.003	0.996	0.000
Chapter XXII Codes for special purposes	0.003	0.996	0.000
I70.9 Generalised and unspecified atherosclerosis	0.003	0.996	0.000
I70.8 Atherosclerosis of other arteries	0.003	0.996	0.000
I70.1 Atherosclerosis of renal artery	0.003	0.996	0.000
I70.0 Atherosclerosis of aorta	0.003	0.996	0.000
S00.1 Contusion of eyelid and periocular area	0.003	0.996	0.000
T65 Toxic effect of other and unspecified substances	0.003	0.996	0.000
T63 Toxic effect of contact with venomous animals	0.003	0.996	0.000
T62 Toxic effect of other noxious substances eaten as food	0.003	0.996	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.003	0.996	0.000
T60 Toxic effect of pesticides	0.003	0.996	0.000
T59 Toxic effect of other gases, fumes and vapours	0.003	0.996	0.000
T57 Toxic effect of other inorganic substances	0.003	0.996	0.000
T56 Toxic effect of metals	0.003	0.996	0.000
T54 Toxic effect of corrosive substances	0.003	0.996	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.003	0.996	0.000
T52 Toxic effect of organic solvents	0.003	0.996	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.003	0.996	0.000
T58 Toxic effect of carbon monoxide	0.003	0.996	0.000
T55 Toxic effect of soaps and detergents	0.003	0.996	0.000
M86-M90 Other osteopathies	0.003	0.996	0.000
M17.0 Primary gonarthrosis, bilateral	0.004	0.996	0.000
S06.9 Intracranial injury, unspecified	0.003	0.996	0.000
S06.8 Other intracranial injuries	0.003	0.996	0.000
S06.7 Intracranial injury with prolonged coma	0.003	0.996	0.000
S06.4 Epidural haemorrhage	0.003	0.996	0.000
S06.3 Focal brain injury	0.003	0.996	0.000
S06.1 Traumatic cerebral oedema	0.003	0.996	0.000
S06.0 Concussion	0.003	0.996	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.996	0.000
M31 Other necrotising vasculopathies	0.003	0.996	0.000
W19 Unspecified fall	0.003	0.996	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.996	0.000
Y58 Bacterial vaccines	0.003	0.996	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.996	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.996	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.996	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.996	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.996	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.996	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.996	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.996	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.996	0.000
Y40 Systemic antibiotics	0.003	0.996	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.003	0.996	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.003	0.996	0.000
C18.3 Hepatic flexure	0.003	0.996	0.000
E11.4 With neurological complications	0.003	0.996	0.000
E13.9 Without complications	0.003	0.996	0.000
M35.3 Polymyalgia rheumatica	0.003	0.996	0.000
S02.6 Fracture of mandible	0.003	0.996	0.000
S09 Other and unspecified injuries of head	0.003	0.996	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.996	0.000
T17 Foreign body in respiratory tract	0.003	0.996	0.000
W44 Foreign body entering into or through eye or natural orifice	0.003	0.996	0.000
H30-H36 Disorders of choroid and retina	0.004	0.996	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.003	0.996	0.000
M19.0 Primary arthrosis of other joints	0.003	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.996	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.996	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
E40-E46 Malnutrition	0.003	0.996	0.000
D25.9 Leiomyoma of uterus, unspecified	0.000	0.996	0.004
I72.9 Aneurysm of unspecified site	0.003	0.996	0.000
I72.8 Aneurysm of other specified arteries	0.003	0.996	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.003	0.996	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.003	0.996	0.000
I72.4 Aneurysm of artery of lower extremity	0.003	0.996	0.000
I72.3 Aneurysm of iliac artery	0.003	0.996	0.000
I72.2 Aneurysm of renal artery	0.003	0.996	0.000
I72.1 Aneurysm of artery of upper extremity	0.003	0.996	0.000
I72.0 Aneurysm of carotid artery	0.003	0.996	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.003	0.996	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.003	0.996	0.000
I79.1 Aortitis in diseases classified elsewhere	0.003	0.996	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.003	0.996	0.000
N18.8 Other chronic renal failure	0.003	0.996	0.000
N18.5 Chronic kidney disease, stage 5	0.003	0.996	0.000
N18.1 Chronic kidney disease, stage 1	0.003	0.996	0.000
T78 Adverse effects, not elsewhere classified	0.003	0.996	0.000
W17 Other fall from one level to another	0.003	0.996	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.003	0.996	0.000
W15 Fall from cliff	0.003	0.996	0.000
W14 Fall from tree	0.003	0.996	0.000
W13 Fall from, out of or through building or structure	0.003	0.996	0.000
W12 Fall on and from scaffolding	0.003	0.996	0.000
W11 Fall on and from ladder	0.003	0.996	0.000
W10 Fall on and from stairs and steps	0.003	0.996	0.000
W09 Fall involving playground equipment	0.003	0.996	0.000
W08 Fall involving other furniture	0.003	0.996	0.000
W06 Fall involving bed	0.003	0.996	0.000
W05 Fall involving wheelchair	0.003	0.996	0.000
W04 Fall while being carried or supported by other persons	0.003	0.996	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.003	0.996	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.003	0.996	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.003	0.996	0.000
W00 Fall on same level involving ice and snow	0.003	0.996	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.996	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.996	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.996	0.000
Y45.4 Antirheumatics	0.003	0.996	0.000
Y45.2 Propionic acid derivatives	0.003	0.996	0.000
Y45.1 Salicylates	0.003	0.996	0.000
D05 Carcinoma in situ of breast	0.003	0.996	0.000
M19 Other arthrosis	0.003	0.996	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.003	0.996	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.996	0.000
T95 Sequelae of burns, corrosions and frostbite	0.003	0.996	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.003	0.996	0.000
T92 Sequelae of injuries of upper limb	0.003	0.996	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.996	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.003	0.996	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.003	0.996	0.000
N18.0 End-stage renal disease	0.003	0.997	0.000
S80 Superficial injury of lower leg	0.003	0.997	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.003	0.997	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.003	0.997	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.997	0.000
Chapter I Certain infectious and parasitic diseases	0.003	0.997	0.000
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
E10.8 With unspecified complications	0.003	0.997	0.000
E10.7 With multiple complications	0.003	0.997	0.000
E10.6 With other specified complications	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
E10.4 With neurological complications	0.003	0.997	0.000
E10.2 With renal complications	0.003	0.997	0.000
E10.1 With ketoacidosis	0.003	0.997	0.000
E10.0 With coma	0.003	0.997	0.000
E11.5 With peripheral circulatory complications	0.003	0.997	0.000
D67 Hereditary factor IX deficiency	0.003	0.997	0.000
D66 Hereditary factor VIII deficiency	0.003	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.997	0.000
M17 Gonarthrosis [arthrosis of knee]	0.003	0.997	0.000
M23.9 Internal derangement of knee, unspecified	0.003	0.997	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.003	0.997	0.000
M23.5 Chronic instability of knee	0.003	0.997	0.000
M23.1 Discoid meniscus (congenital)	0.003	0.997	0.000
M23.0 Cystic meniscus	0.003	0.997	0.000
D68 Other coagulation defects	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.003	0.997	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.003	0.997	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
N43 Hydrocele and spermatocele	0.003	0.997	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.003	0.997	0.000
H55-H59 Other disorders of eye and adnexa	0.003	0.997	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.003	0.997	0.000
M23.8 Other internal derangements of knee	0.003	0.997	0.000
I27 Other pulmonary heart diseases	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.003	0.997	0.000
H10-H13 Disorders of conjunctiva	0.003	0.997	0.000
M91-M94 Chondropathies	0.003	0.997	0.000
M60-M63 Disorders of muscles	0.003	0.997	0.000
M00-M03 Infectious arthropathies	0.003	0.997	0.000
D50 Iron deficiency anaemia	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E29 Testicular dysfunction	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.003	0.997	0.000
H43-H45 Disorders of vitreous body and globe	0.003	0.997	0.000
Chapter XIV Diseases of the genitourinary system	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.37 Other meniscus derangements-Capsular lig	0.003	0.997	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.003	0.997	0.000
I78.9 Disease of capillaries, unspecified	0.003	0.997	0.000
I78.8 Other diseases of capillaries	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.003	0.997	0.000
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
I08 Multiple valve diseases	0.003	0.997	0.000
M65 Synovitis and tenosynovitis	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.003	0.997	0.000
S87 Crushing injury of lower leg	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.003	0.997	0.000
S85 Injury of blood vessels at lower leg level	0.003	0.997	0.000
S84 Injury of nerves at lower leg level	0.003	0.997	0.000
S81 Open wound of lower leg	0.003	0.997	0.000
W22 Striking against or struck by other objects	0.003	0.997	0.000
E55.9 Vitamin D deficiency, unspecified	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
W19.3 Sports and athletics area	0.003	0.997	0.000
L20-L30 Dermatitis and eczema	0.003	0.997	0.000
D05.1 Intraductal carcinoma in situ	0.003	0.997	0.000
D07.5 Prostate	0.003	0.997	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.003	0.997	0.000
I07 Rheumatic tricuspid valve diseases	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
S82 Fracture of lower leg, including ankle	0.003	0.997	0.000
T19 Foreign body in genito-urinary tract	0.003	0.997	0.000
T15 Foreign body on external eye	0.003	0.997	0.000
T16 Foreign body in ear	0.003	0.997	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations