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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76547981
log Bayes Factor = 10.2504
Chromosome 1   position 81,547,822  (GRCh37) Explore rs76547981 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
F30-F39 Mood [affective] disorders
0.988 0.012 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.986 0.014 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.984 0.016 0.000
Chapter VIII Diseases of the ear and mastoid process
0.981 0.019 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.981 0.019 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
H40-H42 Glaucoma
0.979 0.021 0.000
Chapter X Diseases of the respiratory system
0.977 0.023 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.975 0.025 0.000
H30-H36 Disorders of choroid and retina
0.973 0.027 0.000
H40 Glaucoma
0.968 0.032 0.000
H35 Other retinal disorders
0.967 0.033 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.961 0.039 0.000
F31 Bipolar affective disorder
0.955 0.045 0.000
C16 Malignant neoplasm of stomach
0.953 0.047 0.000
H35.3 Degeneration of macula and posterior pole
0.951 0.049 0.000
H80-H83 Diseases of inner ear
0.951 0.049 0.000
G57 Mononeuropathies of lower limb
0.951 0.049 0.000
M15-M19 Arthrosis
0.950 0.050 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.948 0.052 0.000
M45-M49 Spondylopathies
0.947 0.053 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.946 0.054 0.000
J40-J47 Chronic lower respiratory diseases
0.941 0.059 0.000
C15 Malignant neoplasm of oesophagus
0.938 0.062 0.000
M19 Other arthrosis
0.934 0.066 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.928 0.072 0.000
G90-G99 Other disorders of the nervous system
0.927 0.073 0.000
C16.0 Cardia
0.923 0.077 0.000
Y95 Nosocomial condition
0.922 0.078 0.000
G57.6 Lesion of plantar nerve
0.922 0.078 0.000
H40.0 Glaucoma suspect
0.914 0.086 0.000
D00-D09 In situ neoplasms
0.913 0.087 0.000
H40.1 Primary open-angle glaucoma
0.912 0.088 0.000
H65-H75 Diseases of middle ear and mastoid
0.912 0.088 0.000
M86-M90 Other osteopathies
0.911 0.089 0.000
M19.9 Arthrosis, unspecified
0.910 0.090 0.000
F32 Depressive episode
0.905 0.095 0.000
M47 Spondylosis
0.904 0.096 0.000
S70-S79 Injuries to the hip and thigh
0.900 0.100 0.000
J09-J18 Influenza and pneumonia
0.899 0.101 0.000
T66-T78 Other and unspecified effects of external causes
0.893 0.107 0.000
H83 Other diseases of inner ear
0.889 0.111 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.887 0.113 0.000
C78.0 Secondary malignant neoplasm of lung
0.884 0.116 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.878 0.122 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.877 0.123 0.000
C71 Malignant neoplasm of brain
0.876 0.124 0.000
H35.0 Background retinopathy and retinal vascular changes
0.876 0.124 0.000
H71 Cholesteatoma of middle ear
0.876 0.124 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.874 0.126 0.000
C15.5 Lower third of oesophagus
0.868 0.132 0.000
J18 Pneumonia, organism unspecified
0.866 0.134 0.000
C78.7 Secondary malignant neoplasm of liver
0.866 0.134 0.000
C79 Secondary malignant neoplasm of other sites
0.863 0.137 0.000
M19.94 Arthrosis, unspecified (Hand)
0.861 0.139 0.000
M91-M94 Chondropathies
0.861 0.139 0.000
Q50-Q56 Congenital malformations of genital organs
0.860 0.140 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.860 0.140 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.859 0.141 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.859 0.141 0.000
J44 Other chronic obstructive pulmonary disease
0.858 0.142 0.000
J18.1 Lobar pneumonia, unspecified
0.857 0.143 0.000
F60-F69 Disorders of adult personality and behaviour
0.851 0.149 0.000
M20-M25 Other joint disorders
0.850 0.150 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.849 0.151 0.000
G58 Other mononeuropathies
0.848 0.152 0.000
J45 Asthma
0.848 0.152 0.000
H83.0 Labyrinthitis
0.845 0.155 0.000
M48 Other spondylopathies
0.843 0.157 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.840 0.160 0.000
G51 Facial nerve disorders
0.839 0.161 0.000
M47.9 Spondylosis, unspecified
0.836 0.164 0.000
F99-F99 Unspecified mental disorder
0.835 0.165 0.000
H40.2 Primary angle-closure glaucoma
0.831 0.169 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.831 0.169 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.830 0.170 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.830 0.170 0.000
C43 Malignant melanoma of skin
0.830 0.170 0.000
M15 Polyarthrosis
0.829 0.171 0.000
F32.0 Mild depressive episode
0.828 0.172 0.000
M24 Other specific joint derangements
0.828 0.172 0.000
C18 Malignant neoplasm of colon
0.825 0.175 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.822 0.178 0.000
M60-M63 Disorders of muscles
0.821 0.179 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.820 0.180 0.000
J42 Unspecified chronic bronchitis
0.817 0.183 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.815 0.185 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.815 0.185 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.813 0.187 0.000
S72 Fracture of femur
0.811 0.189 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.810 0.190 0.000
J90-J94 Other diseases of pleura
0.809 0.191 0.000
Q80-Q89 Other congenital malformations
0.808 0.192 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.807 0.193 0.000
M19.0 Primary arthrosis of other joints
0.802 0.198 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.801 0.199 0.000
W20-W49 Exposure to inanimate mechanical forces
0.801 0.199 0.000
G54 Nerve root and plexus disorders
0.798 0.202 0.000
V40-V49 Car occupant injured in transport accident
0.797 0.203 0.000
H81 Disorders of vestibular function
0.796 0.204 0.000
T78 Adverse effects, not elsewhere classified
0.795 0.205 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.793 0.207 0.000
C78.2 Secondary malignant neoplasm of pleura
0.793 0.207 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.792 0.208 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.790 0.210 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.789 0.211 0.000
H25-H28 Disorders of lens
0.789 0.211 0.000
H80 Otosclerosis
0.787 0.213 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.787 0.213 0.000
G70-G73 Diseases of myoneural junction and muscle
0.786 0.214 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.786 0.214 0.000
M47.2 Other spondylosis with radiculopathy
0.785 0.215 0.000
F29 Unspecified nonorganic psychosis
0.785 0.215 0.000
G90 Disorders of autonomic nervous system
0.784 0.216 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.783 0.217 0.000
W00-W19 Falls
0.782 0.218 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.782 0.218 0.000
M24.1 Other articular cartilage disorders
0.781 0.219 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.781 0.219 0.000
S50-S59 Injuries to the elbow and forearm
0.780 0.220 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.779 0.221 0.000
J45.9 Asthma, unspecified
0.779 0.221 0.000
H35.4 Peripheral retinal degeneration
0.777 0.223 0.000
G50 Disorders of trigeminal nerve
0.776 0.224 0.000
C15.9 Oesophagus, unspecified
0.774 0.226 0.000
M90 Osteopathies in diseases classified elsewhere
0.774 0.226 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.774 0.226 0.000
X60-X84 Intentional self-harm
0.769 0.231 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.768 0.232 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.767 0.233 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.767 0.233 0.000
F33 Recurrent depressive disorder
0.766 0.234 0.000
J00-J06 Acute upper respiratory infections
0.766 0.234 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.764 0.235 0.000
S72.0 Fracture of neck of femur
0.764 0.236 0.000
M48.0 Spinal stenosis
0.764 0.236 0.000
J95-J99 Other diseases of the respiratory system
0.763 0.237 0.000
C71.9 Brain, unspecified
0.762 0.238 0.000
H74 Other disorders of middle ear and mastoid
0.762 0.238 0.000
S90-S99 Injuries to the ankle and foot
0.762 0.238 0.000
F30 Manic episode
0.761 0.239 0.000
E70-E90 Metabolic disorders
0.761 0.239 0.000
C64-C68 Malignant neoplasms of urinary tract
0.761 0.239 0.000
C20 Malignant neoplasm of rectum
0.760 0.240 0.000
C18.5 Splenic flexure
0.760 0.240 0.000
D03 Melanoma in situ
0.760 0.240 0.000
G57.1 Meralgia paraesthetica
0.759 0.241 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.759 0.241 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.758 0.242 0.000
D04 Carcinoma in situ of skin
0.757 0.243 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.756 0.244 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.753 0.247 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.753 0.247 0.000
M87 Osteonecrosis
0.751 0.249 0.000
H31 Other disorders of choroid
0.750 0.250 0.000
Q60-Q64 Congenital malformations of the urinary system
0.749 0.251 0.000
F60 Specific personality disorders
0.747 0.253 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.746 0.254 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.746 0.254 0.000
M18 Arthrosis of first carpometacarpal joint
0.745 0.255 0.000
H35.2 Other proliferative retinopathy
0.744 0.256 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.743 0.257 0.000
C17 Malignant neoplasm of small intestine
0.743 0.257 0.000
C43.5 Malignant melanoma of trunk
0.743 0.257 0.000
V10-V19 Pedal cyclist injured in transport accident
0.742 0.258 0.000
T79-T79 Certain early complications of trauma
0.742 0.258 0.000
D09 Carcinoma in situ of other and unspecified sites
0.741 0.259 0.000
G58.9 Mononeuropathy, unspecified
0.741 0.259 0.000
T78.3 Angioneurotic oedema
0.741 0.259 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.740 0.259 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.737 0.263 0.000
T42.4 Benzodiazepines
0.736 0.264 0.000
W50-W64 Exposure to animate mechanical forces
0.735 0.265 0.000
S40-S49 Injuries to the shoulder and upper arm
0.734 0.266 0.000
C77.1 Intrathoracic lymph nodes
0.733 0.267 0.000
S72.00 Fracture of neck of femur (closed)
0.731 0.269 0.000
C71.3 Parietal lobe
0.730 0.270 0.000
W25 Contact with sharp glass
0.729 0.270 0.000
M48.02 Spinal stenosis (Cervical region)
0.729 0.271 0.000
M89 Other disorders of bone
0.729 0.271 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.727 0.273 0.000
H55-H59 Other disorders of eye and adnexa
0.726 0.274 0.000
J90 Pleural effusion, not elsewhere classified
0.724 0.276 0.000
G83 Other paralytic syndromes
0.724 0.276 0.000
G82 Paraplegia and tetraplegia
0.724 0.276 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.720 0.280 0.000
F99 Mental disorder, not otherwise specified
0.720 0.280 0.000
Q00-Q07 Congenital malformations of the nervous system
0.719 0.281 0.000
H53-H54 Visual disturbances and blindness
0.719 0.281 0.000
E20-E35 Disorders of other endocrine glands
0.718 0.282 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.718 0.282 0.000
J60-J70 Lung diseases due to external agents
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.716 0.283 0.000
C23 Malignant neoplasm of gallbladder
0.716 0.283 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.716 0.284 0.000
J40 Bronchitis, not specified as acute or chronic
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
M50-M54 Other dorsopathies
0.714 0.286 0.000
F80-F89 Disorders of psychological development
0.713 0.287 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
G93 Other disorders of brain
0.712 0.288 0.000
M40-M43 Deforming dorsopathies
0.712 0.288 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.711 0.288 0.000
C34 Malignant neoplasm of bronchus and lung
0.711 0.289 0.000
Q54 Hypospadias
0.711 0.289 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.710 0.289 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.710 0.290 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.710 0.290 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.709 0.291 0.000
J46 Status asthmaticus
0.709 0.291 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.709 0.291 0.000
F38 Other mood [affective] disorders
0.708 0.292 0.000
F34 Persistent mood [affective] disorders
0.708 0.292 0.000
F39 Unspecified mood [affective] disorder
0.708 0.292 0.000
H34 Retinal vascular occlusions
0.708 0.292 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.708 0.292 0.000
Q35-Q37 Cleft lip and cleft palate
0.708 0.292 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.708 0.292 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.708 0.292 0.000
S79 Other and unspecified injuries of hip and thigh
0.708 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.292 0.000
T33-T35 Frostbite
0.707 0.293 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.293 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.707 0.293 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.293 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.705 0.295 0.000
G52 Disorders of other cranial nerves
0.705 0.295 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.704 0.296 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.703 0.297 0.000
C22.0 Liver cell carcinoma
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
S80-S89 Injuries to the knee and lower leg
0.702 0.298 0.000
Q39 Congenital malformations of oesophagus
0.702 0.298 0.000
H42 Glaucoma in diseases classified elsewhere
0.702 0.298 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.702 0.298 0.000
H66 Suppurative and unspecified otitis media
0.701 0.299 0.000
M00-M03 Infectious arthropathies
0.701 0.299 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.701 0.299 0.000
M21 Other acquired deformities of limbs
0.701 0.299 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.700 0.300 0.000
H40.9 Glaucoma, unspecified
0.700 0.300 0.000
C79.6 Secondary malignant neoplasm of ovary
0.700 0.300 0.000
S10-S19 Injuries to the neck
0.700 0.300 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.301 0.000
S32 Fracture of lumbar spine and pelvis
0.698 0.301 0.000
H35.5 Hereditary retinal dystrophy
0.698 0.302 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.698 0.302 0.000
H30 Chorioretinal inflammation
0.698 0.302 0.000
Q66 Congenital deformities of feet
0.697 0.302 0.000
C21 Malignant neoplasm of anus and anal canal
0.696 0.304 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.696 0.304 0.000
C71.1 Frontal lobe
0.695 0.305 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.695 0.305 0.000
T75 Effects of other external causes
0.695 0.305 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.694 0.306 0.000
H40.8 Other glaucoma
0.694 0.306 0.000
H40.6 Glaucoma secondary to drugs
0.694 0.306 0.000
H40.4 Glaucoma secondary to eye inflammation
0.694 0.306 0.000
H40.3 Glaucoma secondary to eye trauma
0.694 0.306 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.694 0.306 0.000
F22 Persistent delusional disorders
0.694 0.306 0.000
M62 Other disorders of muscle
0.694 0.306 0.000
M24.0 Loose body in joint
0.694 0.306 0.000
G91 Hydrocephalus
0.693 0.306 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.693 0.307 0.000
H35.7 Separation of retinal layers
0.693 0.307 0.000
H35.1 Retinopathy of prematurity
0.693 0.307 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.693 0.307 0.000
J43 Emphysema
0.692 0.308 0.000
F41 Other anxiety disorders
0.691 0.309 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.691 0.309 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.691 0.309 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.690 0.310 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.690 0.310 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.690 0.310 0.000
C71.2 Temporal lobe
0.689 0.311 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.689 0.311 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.689 0.311 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.689 0.311 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.689 0.311 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.689 0.311 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.689 0.311 0.000
T36 Poisoning by systemic antibiotics
0.689 0.311 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.688 0.312 0.000
M94 Other disorders of cartilage
0.688 0.312 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.687 0.313 0.000
F31.8 Other bipolar affective disorders
0.685 0.315 0.000
F31.7 Bipolar affective disorder, currently in remission
0.685 0.315 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.685 0.315 0.000
M47.8 Other spondylosis
0.685 0.315 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.684 0.316 0.000
H36 Retinal disorders in diseases classified elsewhere
0.684 0.316 0.000
G95 Other diseases of spinal cord
0.683 0.316 0.000
C16.8 Overlapping lesion of stomach
0.683 0.317 0.000
C16.6 Greater curvature of stomach, unspecified
0.683 0.317 0.000
C16.5 Lesser curvature of stomach, unspecified
0.683 0.317 0.000
C16.4 Pylorus
0.683 0.317 0.000
C16.3 Pyloric antrum
0.683 0.317 0.000
C16.2 Body of stomach
0.683 0.317 0.000
C16.1 Fundus of stomach
0.683 0.317 0.000
M93 Other osteochondropathies
0.683 0.317 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.682 0.318 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.682 0.318 0.000
G57.5 Tarsal tunnel syndrome
0.682 0.318 0.000
G57.4 Lesion of medial popliteal nerve
0.682 0.318 0.000
G57.3 Lesion of lateral popliteal nerve
0.682 0.318 0.000
G57.2 Lesion of femoral nerve
0.682 0.318 0.000
G57.0 Lesion of sciatic nerve
0.682 0.318 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.682 0.318 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.681 0.319 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.681 0.319 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.679 0.320 0.000
Y98 Lifestyle-related condition
0.679 0.320 0.000
Y97 Environmental-pollution-related condition
0.679 0.320 0.000
Y96 Work-related condition
0.679 0.320 0.000
H90-H95 Other disorders of ear
0.679 0.321 0.000
M49 Spondylopathies in diseases classified elsewhere
0.679 0.321 0.000
W25.9 Unspecified place
0.679 0.321 0.000
M15.1 Heberden's nodes (with arthropathy)
0.678 0.322 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.678 0.322 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.678 0.322 0.000
W13 Fall from, out of or through building or structure
0.676 0.324 0.000
M90.7 Fracture of bone in neoplastic disease
0.676 0.324 0.000
H35.8 Other specified retinal disorders
0.675 0.325 0.000
Q76 Congenital malformations of spine and bony thorax
0.675 0.325 0.000
M19.1 Posttraumatic arthrosis of other joints
0.675 0.325 0.000
J41 Simple and mucopurulent chronic bronchitis
0.675 0.325 0.000
F32.1 Moderate depressive episode
0.675 0.325 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.675 0.325 0.000
G51.0 Bell's palsy
0.674 0.326 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.674 0.326 0.000
M30 Polyarteritis nodosa and related conditions
0.674 0.326 0.000
C15.8 Overlapping lesion of oesophagus
0.673 0.327 0.000
C15.4 Middle third of oesophagus
0.673 0.327 0.000
C15.3 Upper third of oesophagus
0.673 0.327 0.000
C15.2 Abdominal part of oesophagus
0.673 0.327 0.000
C15.1 Thoracic part of oesophagus
0.673 0.327 0.000
C15.0 Cervical part of oesophagus
0.673 0.327 0.000
M86 Osteomyelitis
0.673 0.327 0.000
T68 Hypothermia
0.673 0.327 0.000
M92 Other juvenile osteochondrosis
0.672 0.328 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.671 0.329 0.000
V80-V89 Other land transport accidents
0.671 0.329 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.671 0.329 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.670 0.329 0.000
E73 Lactose intolerance
0.670 0.330 0.000
H80.9 Otosclerosis, unspecified
0.670 0.330 0.000
G51.8 Other disorders of facial nerve
0.670 0.330 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.670 0.330 0.000
M19.8 Other specified arthrosis
0.669 0.330 0.000
M19.2 Other secondary arthrosis
0.669 0.330 0.000
F41.2 Mixed anxiety and depressive disorder
0.668 0.332 0.000
S70 Superficial injury of hip and thigh
0.668 0.332 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.665 0.335 0.000
C70 Malignant neoplasm of meninges
0.665 0.335 0.000
C69 Malignant neoplasm of eye and adnexa
0.665 0.335 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.665 0.335 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.665 0.335 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.665 0.335 0.000
G92 Toxic encephalopathy
0.665 0.335 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.665 0.335 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.664 0.336 0.000
J14 Pneumonia due to Haemophilus influenzae
0.662 0.338 0.000
D03.5 Melanoma in situ of trunk
0.661 0.339 0.000
H81.0 Meniere's disease
0.660 0.340 0.000
M80-M85 Disorders of bone density and structure
0.660 0.340 0.000
Q82 Other congenital malformations of skin
0.660 0.340 0.000
M32 Systemic lupus erythematosus
0.657 0.343 0.000
C77.9 Lymph node, unspecified
0.657 0.343 0.000
H73 Other disorders of tympanic membrane
0.657 0.343 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.655 0.345 0.000
D07.2 Vagina
0.655 0.345 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.654 0.345 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.654 0.345 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.654 0.345 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.654 0.346 0.000
H70 Mastoiditis and related conditions
0.654 0.346 0.000
H68 Eustachian salpingitis and obstruction
0.654 0.346 0.000
H67 Otitis media in diseases classified elsewhere
0.654 0.346 0.000
H35.6 Retinal haemorrhage
0.653 0.347 0.000
H50 Other strabismus
0.652 0.348 0.000
G71 Primary disorders of muscles
0.652 0.348 0.000
H25 Senile cataract
0.651 0.349 0.000
J98 Other respiratory disorders
0.651 0.349 0.000
D04.5 Skin of trunk
0.650 0.350 0.000
Q65 Congenital deformities of hip
0.650 0.350 0.000
F32.8 Other depressive episodes
0.649 0.351 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.648 0.352 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.648 0.352 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.648 0.352 0.000
C18.4 Transverse colon
0.647 0.352 0.000
G80 Infantile cerebral palsy
0.647 0.353 0.000
V20-V29 Motorcycle rider injured in transport accident
0.646 0.354 0.000
E40-E46 Malnutrition
0.646 0.354 0.000
C16.9 Stomach, unspecified
0.646 0.354 0.000
S78 Traumatic amputation of hip and thigh
0.645 0.355 0.000
S77 Crushing injury of hip and thigh
0.645 0.355 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.645 0.355 0.000
S75 Injury of blood vessels at hip and thigh level
0.645 0.355 0.000
S74 Injury of nerves at hip and thigh level
0.645 0.355 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.645 0.355 0.000
S71 Open wound of hip and thigh
0.645 0.355 0.000
J17 Pneumonia in diseases classified elsewhere
0.645 0.355 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.645 0.355 0.000
J12 Viral pneumonia, not elsewhere classified
0.645 0.355 0.000
J11 Influenza, virus not identified
0.645 0.355 0.000
J09 Influenza due to certain identified influenza virus
0.645 0.355 0.000
H54 Blindness and low vision
0.645 0.355 0.000
H10-H13 Disorders of conjunctiva
0.643 0.357 0.000
F43 Reaction to severe stress, and adjustment disorders
0.643 0.357 0.000
E86 Volume depletion
0.643 0.357 0.000
G96 Other disorders of central nervous system
0.642 0.358 0.000
H74.4 Polyp of middle ear
0.642 0.358 0.000
T74 Maltreatment syndromes
0.640 0.360 0.000
T73 Effects of other deprivation
0.640 0.360 0.000
T70 Effects of air pressure and water pressure
0.640 0.360 0.000
T69 Other effects of reduced temperature
0.640 0.360 0.000
T67 Effects of heat and light
0.640 0.360 0.000
T71 Asphyxiation
0.640 0.360 0.000
T66 Unspecified effects of radiation
0.640 0.360 0.000
H69 Other disorders of Eustachian tube
0.640 0.360 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.640 0.360 0.000
J00 Acute nasopharyngitis [common cold]
0.640 0.360 0.000
G03 Meningitis due to other and unspecified causes
0.639 0.361 0.000
M19.98 Arthrosis, unspecified (Other)
0.639 0.361 0.000
G57.8 Other mononeuropathies of lower limb
0.638 0.362 0.000
T40.6 Other and unspecified narcotics
0.638 0.362 0.000
F42 Obsessive-compulsive disorder
0.638 0.362 0.000
H83.9 Disease of inner ear, unspecified
0.637 0.362 0.000
H83.8 Other specified diseases of inner ear
0.637 0.362 0.000
H83.3 Noise effects on inner ear
0.637 0.362 0.000
H83.2 Labyrinthine dysfunction
0.637 0.362 0.000
H83.1 Labyrinthine fistula
0.637 0.362 0.000
G81 Hemiplegia
0.637 0.363 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.636 0.363 0.000
T40.2 Other opioids
0.636 0.364 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.636 0.364 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.636 0.364 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.636 0.364 0.000
T42.3 Barbiturates
0.636 0.364 0.000
T42.2 Succinimides and oxazolidinediones
0.636 0.364 0.000
T42.1 Iminostilbenes
0.636 0.364 0.000
T42.0 Hydantoin derivatives
0.636 0.364 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.635 0.365 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.634 0.366 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.634 0.366 0.000
F60.9 Personality disorder, unspecified
0.634 0.366 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.633 0.366 0.000
M87.9 Osteonecrosis, unspecified
0.633 0.367 0.000
C18.3 Hepatic flexure
0.633 0.367 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.632 0.367 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.632 0.368 0.000
E87.5 Hyperkalaemia
0.632 0.368 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.632 0.368 0.000
G58.8 Other specified mononeuropathies
0.631 0.369 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.630 0.369 0.000
S72.3 Fracture of shaft of femur
0.630 0.370 0.000
F23 Acute and transient psychotic disorders
0.630 0.370 0.000
F28 Other nonorganic psychotic disorders
0.630 0.370 0.000
F24 Induced delusional disorder
0.630 0.370 0.000
F21 Schizotypal disorder
0.630 0.370 0.000
C71.8 Overlapping lesion of brain
0.628 0.372 0.000
C71.7 Brain stem
0.628 0.372 0.000
C71.6 Cerebellum
0.628 0.372 0.000
C71.5 Cerebral ventricle
0.628 0.372 0.000
C71.4 Occipital lobe
0.628 0.372 0.000
C71.0 Cerebrum, except lobes and ventricles
0.628 0.372 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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