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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76570619
log Bayes Factor = 1.1837
Chromosome 1   position 113,246,730  (GRCh37) Explore rs76570619 on Ensembl!
Variant rs76570619 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
0.930 0.070 0.000
D10-D36 Benign neoplasms
0.928 0.072 0.000
# Top node
0.927 0.073 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.915 0.085 0.000
D25 Leiomyoma of uterus
0.908 0.092 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.902 0.098 0.000
Chapter X Diseases of the respiratory system
0.883 0.117 0.000
D17 Benign lipomatous neoplasm
0.876 0.124 0.000
D25.9 Leiomyoma of uterus, unspecified
0.872 0.128 0.000
C64-C68 Malignant neoplasms of urinary tract
0.861 0.139 0.000
Chapter VII Diseases of the eye and adnexa
0.857 0.143 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.846 0.154 0.000
D60-D64 Aplastic and other anaemias
0.833 0.167 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.833 0.167 0.000
Chapter XI Diseases of the digestive system
0.829 0.171 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.816 0.184 0.000
C67 Malignant neoplasm of bladder
0.811 0.189 0.000
D00-D09 In situ neoplasms
0.809 0.191 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.807 0.193 0.000
K65-K67 Diseases of peritoneum
0.805 0.195 0.000
D24 Benign neoplasm of breast
0.802 0.198 0.000
D25.1 Intramural leiomyoma of uterus
0.801 0.199 0.000
K30 Dyspepsia
0.798 0.202 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.794 0.206 0.000
D27 Benign neoplasm of ovary
0.791 0.209 0.000
J90-J94 Other diseases of pleura
0.789 0.211 0.000
S80-S89 Injuries to the knee and lower leg
0.782 0.218 0.000
K66 Other disorders of peritoneum
0.779 0.221 0.000
H30-H36 Disorders of choroid and retina
0.776 0.224 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.776 0.224 0.000
J20-J22 Other acute lower respiratory infections
0.770 0.230 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.768 0.232 0.000
J40-J47 Chronic lower respiratory diseases
0.767 0.233 0.000
C51-C58 Malignant neoplasms of female genital organs
0.765 0.235 0.000
K66.0 Peritoneal adhesions
0.761 0.239 0.000
D25.2 Subserosal leiomyoma of uterus
0.750 0.250 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.747 0.253 0.000
K29 Gastritis and duodenitis
0.747 0.253 0.000
J95-J99 Other diseases of the respiratory system
0.747 0.253 0.000
H53-H54 Visual disturbances and blindness
0.747 0.253 0.000
D64 Other anaemias
0.745 0.255 0.000
C67.9 Bladder, unspecified
0.744 0.256 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.735 0.265 0.000
D50-D53 Nutritional anaemias
0.734 0.266 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.731 0.269 0.000
D70 Agranulocytosis
0.731 0.269 0.000
E10-E14 Diabetes mellitus
0.731 0.269 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.728 0.272 0.000
D80-D89 Certain disorders involving the immune mechanism
0.727 0.273 0.000
K29.8 Duodenitis
0.726 0.274 0.000
Chapter VIII Diseases of the ear and mastoid process
0.726 0.274 0.000
D23 Other benign neoplasms of skin
0.725 0.275 0.000
J90 Pleural effusion, not elsewhere classified
0.724 0.276 0.000
S60-S69 Injuries to the wrist and hand
0.722 0.278 0.000
Chapter XX External causes of morbidity and mortality
0.718 0.282 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.717 0.283 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.712 0.287 0.000
J44 Other chronic obstructive pulmonary disease
0.711 0.289 0.000
H35 Other retinal disorders
0.701 0.298 0.000
T66-T78 Other and unspecified effects of external causes
0.697 0.302 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.694 0.306 0.000
D22 Melanocytic naevi
0.693 0.307 0.000
S20-S29 Injuries to the thorax
0.693 0.307 0.000
H52 Disorders of refraction and accommodation
0.693 0.307 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.691 0.309 0.000
J22 Unspecified acute lower respiratory infection
0.690 0.310 0.000
K22 Other diseases of oesophagus
0.688 0.312 0.000
C67.2 Lateral wall of bladder
0.687 0.313 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.686 0.314 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.682 0.318 0.000
D64.9 Anaemia, unspecified
0.682 0.318 0.000
D18 Haemangioma and lymphangioma, any site
0.677 0.323 0.000
D05 Carcinoma in situ of breast
0.677 0.323 0.000
K29.6 Other gastritis
0.677 0.323 0.000
D61 Other aplastic anaemias
0.677 0.323 0.000
S50-S59 Injuries to the elbow and forearm
0.676 0.324 0.000
Chapter V Mental and behavioural disorders
0.675 0.325 0.000
S40-S49 Injuries to the shoulder and upper arm
0.674 0.326 0.000
Chapter XXII Codes for special purposes
0.673 0.326 0.000
K70-K77 Diseases of liver
0.669 0.331 0.000
S82 Fracture of lower leg, including ankle
0.667 0.333 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.667 0.333 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.667 0.333 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.667 0.333 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.667 0.333 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.667 0.333 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.667 0.333 0.000
C78.0 Secondary malignant neoplasm of lung
0.666 0.334 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.665 0.335 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.665 0.335 0.000
D31 Benign neoplasm of eye and adnexa
0.665 0.335 0.000
D30 Benign neoplasm of urinary organs
0.665 0.335 0.000
D29 Benign neoplasm of male genital organs
0.665 0.335 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.665 0.335 0.000
D26 Other benign neoplasms of uterus
0.665 0.335 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.665 0.335 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.665 0.335 0.000
D19 Benign neoplasm of mesothelial tissue
0.665 0.335 0.000
D16 Benign neoplasm of bone and articular cartilage
0.665 0.335 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.665 0.335 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.665 0.335 0.000
D10 Benign neoplasm of mouth and pharynx
0.665 0.335 0.000
D34 Benign neoplasm of thyroid gland
0.665 0.335 0.000
E70-E90 Metabolic disorders
0.665 0.335 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.665 0.335 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.661 0.339 0.000
D75 Other diseases of blood and blood-forming organs
0.658 0.342 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.657 0.343 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.657 0.343 0.000
D55-D59 Haemolytic anaemias
0.656 0.344 0.000
S90-S99 Injuries to the ankle and foot
0.655 0.345 0.000
K65 Peritonitis
0.654 0.346 0.000
D32 Benign neoplasm of meninges
0.652 0.347 0.000
D09 Carcinoma in situ of other and unspecified sites
0.651 0.348 0.000
D73 Diseases of spleen
0.649 0.351 0.000
E20-E35 Disorders of other endocrine glands
0.648 0.352 0.000
T79-T79 Certain early complications of trauma
0.646 0.354 0.000
T33-T35 Frostbite
0.646 0.354 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.646 0.354 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.646 0.354 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.646 0.354 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.646 0.354 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.646 0.354 0.000
T00-T07 Injuries involving multiple body regions
0.646 0.354 0.000
S10-S19 Injuries to the neck
0.646 0.354 0.000
D36 Benign neoplasm of other and unspecified sites
0.646 0.354 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.644 0.356 0.000
E16 Other disorders of pancreatic internal secretion
0.644 0.356 0.000
H35.3 Degeneration of macula and posterior pole
0.643 0.357 0.000
S70-S79 Injuries to the hip and thigh
0.641 0.359 0.000
C78.2 Secondary malignant neoplasm of pleura
0.639 0.361 0.000
D11 Benign neoplasm of major salivary glands
0.638 0.362 0.000
S00-S09 Injuries to the head
0.636 0.364 0.000
C56 Malignant neoplasm of ovary
0.634 0.366 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.633 0.366 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.633 0.367 0.000
H53 Visual disturbances
0.633 0.367 0.000
J60-J70 Lung diseases due to external agents
0.632 0.368 0.000
J98 Other respiratory disorders
0.630 0.370 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.628 0.372 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.628 0.372 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.628 0.372 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.628 0.372 0.000
J43 Emphysema
0.625 0.375 0.000
E10 Insulin-dependent diabetes mellitus
0.624 0.375 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.624 0.376 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.623 0.376 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.617 0.382 0.000
C66 Malignant neoplasm of ureter
0.617 0.382 0.000
C65 Malignant neoplasm of renal pelvis
0.617 0.382 0.000
H55-H59 Other disorders of eye and adnexa
0.615 0.385 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.615 0.385 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.615 0.385 0.000
H10-H13 Disorders of conjunctiva
0.615 0.385 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.614 0.386 0.000
S81 Open wound of lower leg
0.609 0.391 0.000
D23.1 Skin of eyelid, including canthus
0.607 0.393 0.000
E40-E46 Malnutrition
0.607 0.393 0.000
S82.8 Fractures of other parts of lower leg
0.605 0.395 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.605 0.395 0.000
H36 Retinal disorders in diseases classified elsewhere
0.604 0.396 0.000
E50-E64 Other nutritional deficiencies
0.603 0.397 0.000
C60-C63 Malignant neoplasms of male genital organs
0.602 0.398 0.000
H54 Blindness and low vision
0.599 0.401 0.000
J09-J18 Influenza and pneumonia
0.598 0.402 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.597 0.402 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.597 0.403 0.000
D62 Acute posthaemorrhagic anaemia
0.597 0.403 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.597 0.403 0.000
D74 Methaemoglobinaemia
0.597 0.403 0.000
D72 Other disorders of white blood cells
0.597 0.403 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.597 0.403 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.597 0.403 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.596 0.404 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.596 0.404 0.000
D23.6 Skin of upper limb, including shoulder
0.595 0.405 0.000
H52.1 Myopia
0.593 0.406 0.000
H90-H95 Other disorders of ear
0.593 0.407 0.000
D86 Sarcoidosis
0.593 0.407 0.000
E11 Non-insulin-dependent diabetes mellitus
0.592 0.408 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.591 0.409 0.000
S80 Superficial injury of lower leg
0.588 0.412 0.000
D50 Iron deficiency anaemia
0.587 0.413 0.000
H52.3 Anisometropia and aniseikonia
0.587 0.413 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.586 0.414 0.000
T51 Toxic effect of alcohol
0.585 0.415 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.584 0.416 0.000
E16.2 Hypoglycaemia, unspecified
0.583 0.417 0.000
K31 Other diseases of stomach and duodenum
0.582 0.418 0.000
H50 Other strabismus
0.582 0.418 0.000
C67.8 Overlapping lesion of bladder
0.581 0.418 0.000
C67.7 Urachus
0.581 0.418 0.000
C67.6 Ureteric orifice
0.581 0.418 0.000
C67.5 Bladder neck
0.581 0.418 0.000
C67.4 Posterior wall of bladder
0.581 0.418 0.000
C67.3 Anterior wall of bladder
0.581 0.418 0.000
C67.1 Dome of bladder
0.581 0.418 0.000
C67.0 Trigone of bladder
0.581 0.418 0.000
D04 Carcinoma in situ of skin
0.580 0.420 0.000
D03 Melanoma in situ
0.580 0.420 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.580 0.420 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.580 0.420 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.580 0.420 0.000
D06 Carcinoma in situ of cervix uteri
0.579 0.421 0.000
K28 Gastrojejunal ulcer
0.579 0.421 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.579 0.421 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.577 0.423 0.000
H60-H62 Diseases of external ear
0.576 0.424 0.000
H43-H45 Disorders of vitreous body and globe
0.576 0.424 0.000
K22.9 Disease of oesophagus, unspecified
0.575 0.425 0.000
J42 Unspecified chronic bronchitis
0.574 0.426 0.000
D68 Other coagulation defects
0.574 0.426 0.000
C54 Malignant neoplasm of corpus uteri
0.572 0.428 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.571 0.429 0.000
D69 Purpura and other haemorrhagic conditions
0.570 0.430 0.000
K27 Peptic ulcer, site unspecified
0.569 0.431 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.566 0.434 0.000
J94 Other pleural conditions
0.566 0.434 0.000
J92 Pleural plaque
0.566 0.434 0.000
J91 Pleural effusion in conditions classified elsewhere
0.566 0.434 0.000
H53.0 Amblyopia ex anopsia
0.566 0.434 0.000
K22.1 Ulcer of oesophagus
0.566 0.434 0.000
S61 Open wound of wrist and hand
0.566 0.434 0.000
D61.9 Aplastic anaemia, unspecified
0.564 0.436 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.562 0.438 0.000
S89 Other and unspecified injuries of lower leg
0.561 0.439 0.000
S88 Traumatic amputation of lower leg
0.561 0.439 0.000
S87 Crushing injury of lower leg
0.561 0.439 0.000
S86 Injury of muscle and tendon at lower leg level
0.561 0.439 0.000
S85 Injury of blood vessels at lower leg level
0.561 0.439 0.000
S84 Injury of nerves at lower leg level
0.561 0.439 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.561 0.439 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.561 0.439 0.000
J93 Pneumothorax
0.561 0.439 0.000
K66.9 Disorder of peritoneum, unspecified
0.559 0.441 0.000
K66.8 Other specified disorders of peritoneum
0.559 0.441 0.000
K66.1 Haemoperitoneum
0.559 0.441 0.000
C34 Malignant neoplasm of bronchus and lung
0.557 0.443 0.000
H34 Retinal vascular occlusions
0.556 0.444 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.556 0.444 0.000
H31 Other disorders of choroid
0.556 0.444 0.000
H30 Chorioretinal inflammation
0.556 0.444 0.000
C80 Malignant neoplasm without specification of site
0.556 0.444 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.556 0.444 0.000
K22.2 Oesophageal obstruction
0.556 0.444 0.000
H33 Retinal detachments and breaks
0.554 0.446 0.000
S68 Traumatic amputation of wrist and hand
0.553 0.446 0.000
J21 Acute bronchiolitis
0.552 0.447 0.000
J20 Acute bronchitis
0.552 0.447 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.551 0.449 0.000
T78 Adverse effects, not elsewhere classified
0.551 0.449 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.551 0.449 0.000
H51 Other disorders of binocular movement
0.550 0.449 0.000
H49 Paralytic strabismus
0.550 0.449 0.000
D51 Vitamin B12 deficiency anaemia
0.550 0.450 0.000
D22.0 Melanocytic naevi of lip
0.550 0.450 0.000
J41 Simple and mucopurulent chronic bronchitis
0.550 0.450 0.000
J46 Status asthmaticus
0.550 0.450 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.549 0.451 0.000
C53 Malignant neoplasm of cervix uteri
0.549 0.451 0.000
C51 Malignant neoplasm of vulva
0.549 0.451 0.000
C58 Malignant neoplasm of placenta
0.549 0.451 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.549 0.451 0.000
C52 Malignant neoplasm of vagina
0.549 0.451 0.000
J98.1 Pulmonary collapse
0.546 0.454 0.000
D23.7 Skin of lower limb, including hip
0.546 0.454 0.000
K65.0 Acute peritonitis
0.546 0.454 0.000
J80 Adult respiratory distress syndrome
0.545 0.455 0.000
E00-E07 Disorders of thyroid gland
0.544 0.456 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.544 0.456 0.000
D50.8 Other iron deficiency anaemias
0.544 0.456 0.000
E65-E68 Obesity and other hyperalimentation
0.543 0.457 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.543 0.457 0.000
K35-K38 Diseases of appendix
0.542 0.457 0.000
H25-H28 Disorders of lens
0.540 0.460 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.539 0.461 0.000
D09.0 Bladder
0.539 0.461 0.000
S40 Superficial injury of shoulder and upper arm
0.538 0.461 0.000
V20-V29 Motorcycle rider injured in transport accident
0.538 0.462 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.537 0.463 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.536 0.464 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.536 0.464 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.536 0.464 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.536 0.464 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.536 0.464 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.536 0.464 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.536 0.464 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.536 0.464 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.536 0.464 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.536 0.464 0.000
T36 Poisoning by systemic antibiotics
0.536 0.464 0.000
K29.9 Gastroduodenitis, unspecified
0.535 0.464 0.000
K29.4 Chronic atrophic gastritis
0.535 0.464 0.000
K29.3 Chronic superficial gastritis
0.535 0.464 0.000
K29.2 Alcoholic gastritis
0.535 0.464 0.000
K29.0 Acute haemorrhagic gastritis
0.535 0.464 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.535 0.464 0.000
J96 Respiratory failure, not elsewhere classified
0.535 0.464 0.000
D25.0 Submucous leiomyoma of uterus
0.534 0.465 0.000
K90-K93 Other diseases of the digestive system
0.534 0.466 0.000
D64.8 Other specified anaemias
0.534 0.466 0.000
D64.4 Congenital dyserythropoietic anaemia
0.534 0.466 0.000
D64.3 Other sideroblastic anaemias
0.534 0.466 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.534 0.466 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.534 0.466 0.000
D64.0 Hereditary sideroblastic anaemia
0.534 0.466 0.000
K13 Other diseases of lip and oral mucosa
0.534 0.466 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.534 0.466 0.000
C50-C50 Malignant neoplasm of breast
0.534 0.466 0.000
E10.1 With ketoacidosis
0.533 0.466 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.533 0.467 0.000
D75.1 Secondary polycythaemia
0.533 0.467 0.000
H35.0 Background retinopathy and retinal vascular changes
0.532 0.468 0.000
S51 Open wound of forearm
0.530 0.470 0.000
K76 Other diseases of liver
0.530 0.470 0.000
S62 Fracture at wrist and hand level
0.530 0.470 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.529 0.471 0.000
D22.4 Melanocytic naevi of scalp and neck
0.527 0.473 0.000
D67 Hereditary factor IX deficiency
0.527 0.473 0.000
D66 Hereditary factor VIII deficiency
0.527 0.473 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.527 0.473 0.000
D53 Other nutritional anaemias
0.526 0.474 0.000
D52 Folate deficiency anaemia
0.526 0.474 0.000
J00-J06 Acute upper respiratory infections
0.524 0.475 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.524 0.476 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.524 0.476 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.524 0.476 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.524 0.476 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.524 0.476 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.524 0.476 0.000
J43.9 Emphysema, unspecified
0.524 0.476 0.000
E13 Other specified diabetes mellitus
0.524 0.476 0.000
E12 Malnutrition-related diabetes mellitus
0.524 0.476 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.524 0.476 0.000
T43.2 Other and unspecified antidepressants
0.523 0.477 0.000
C15-C26 Malignant neoplasms of digestive organs
0.523 0.477 0.000
E15 Nondiabetic hypoglycaemic coma
0.522 0.478 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.521 0.478 0.000
D84 Other immunodeficiencies
0.521 0.478 0.000
D83 Common variable immunodeficiency
0.521 0.478 0.000
D82 Immunodeficiency associated with other major defects
0.521 0.478 0.000
D81 Combined immunodeficiencies
0.521 0.478 0.000
D80 Immunodeficiency with predominantly antibody defects
0.521 0.478 0.000
K26 Duodenal ulcer
0.521 0.479 0.000
Chapter VI Diseases of the nervous system
0.520 0.480 0.000
D23.9 Skin, unspecified
0.520 0.480 0.000
D23.4 Skin of scalp and neck
0.520 0.480 0.000
D23.2 Skin of ear and external auricular canal
0.520 0.480 0.000
D23.0 Skin of lip
0.520 0.480 0.000
D73.0 Hyposplenism
0.518 0.482 0.000
S69 Other and unspecified injuries of wrist and hand
0.517 0.482 0.000
S67 Crushing injury of wrist and hand
0.517 0.482 0.000
S65 Injury of blood vessels at wrist and hand level
0.517 0.482 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.517 0.482 0.000
S60 Superficial injury of wrist and hand
0.517 0.482 0.000
F99-F99 Unspecified mental disorder
0.517 0.483 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.515 0.485 0.000
Y35-Y36 Legal intervention and operations of war
0.515 0.485 0.000
Y10-Y34 Event of undetermined intent
0.515 0.485 0.000
Y00-Y09 Assault
0.515 0.485 0.000
X85-X99 Assault
0.515 0.485 0.000
X60-X84 Intentional self-harm
0.515 0.485 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.515 0.485 0.000
X50-X57 Overexertion, travel and privation
0.515 0.485 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.515 0.485 0.000
X30-X39 Exposure to forces of nature
0.515 0.485 0.000
X20-X29 Contact with venomous animals and plants
0.515 0.485 0.000
X10-X19 Contact with heat and hot substances
0.515 0.485 0.000
X00-X09 Exposure to smoke, fire and flames
0.515 0.485 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.515 0.485 0.000
W75-W84 Other accidental threats to breathing
0.515 0.485 0.000
W65-W74 Accidental drowning and submersion
0.515 0.485 0.000
W50-W64 Exposure to animate mechanical forces
0.515 0.485 0.000
W20-W49 Exposure to inanimate mechanical forces
0.515 0.485 0.000
V98-V99 Other and unspecified transport accidents
0.515 0.485 0.000
V95-V97 Air and space transport accidents
0.515 0.485 0.000
V90-V94 Water transport accidents
0.515 0.485 0.000
V80-V89 Other land transport accidents
0.515 0.485 0.000
V70-V79 Bus occupant injured in transport accident
0.515 0.485 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.515 0.485 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.515 0.485 0.000
V40-V49 Car occupant injured in transport accident
0.515 0.485 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.515 0.485 0.000
V10-V19 Pedal cyclist injured in transport accident
0.515 0.485 0.000
V01-V09 Pedestrian injured in transport accident
0.515 0.485 0.000
S64 Injury of nerves at wrist and hand level
0.515 0.485 0.000
K74 Fibrosis and cirrhosis of liver
0.514 0.486 0.000
T65 Toxic effect of other and unspecified substances
0.514 0.486 0.000
T63 Toxic effect of contact with venomous animals
0.514 0.486 0.000
T62 Toxic effect of other noxious substances eaten as food
0.514 0.486 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.514 0.486 0.000
T60 Toxic effect of pesticides
0.514 0.486 0.000
T59 Toxic effect of other gases, fumes and vapours
0.514 0.486 0.000
T57 Toxic effect of other inorganic substances
0.514 0.486 0.000
T56 Toxic effect of metals
0.514 0.486 0.000
T54 Toxic effect of corrosive substances
0.514 0.486 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.514 0.486 0.000
T52 Toxic effect of organic solvents
0.514 0.486 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.514 0.486 0.000
T58 Toxic effect of carbon monoxide
0.514 0.486 0.000
T55 Toxic effect of soaps and detergents
0.514 0.486 0.000
E27 Other disorders of adrenal gland
0.514 0.486 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.514 0.486 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.513 0.487 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.512 0.488 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.512 0.488 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.511 0.489 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.511 0.489 0.000
C32 Malignant neoplasm of larynx
0.511 0.489 0.000
C31 Malignant neoplasm of accessory sinuses
0.511 0.489 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.511 0.489 0.000
C37 Malignant neoplasm of thymus
0.511 0.489 0.000
C33 Malignant neoplasm of trachea
0.511 0.489 0.000
K11 Diseases of salivary glands
0.510 0.490 0.000
C79 Secondary malignant neoplasm of other sites
0.509 0.491 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.508 0.492 0.000
T39.1 4-Aminophenol derivatives
0.507 0.493 0.000
C78.7 Secondary malignant neoplasm of liver
0.506 0.494 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.506 0.494 0.000
L50-L54 Urticaria and erythema
0.504 0.496 0.000
H35.9 Retinal disorder, unspecified
0.503 0.497 0.000
H35.7 Separation of retinal layers
0.503 0.497 0.000
H35.6 Retinal haemorrhage
0.503 0.497 0.000
H35.5 Hereditary retinal dystrophy
0.503 0.497 0.000
H35.4 Peripheral retinal degeneration
0.503 0.497 0.000
H35.2 Other proliferative retinopathy
0.503 0.497 0.000
H35.1 Retinopathy of prematurity
0.503 0.497 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.503 0.497 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.502 0.497 0.000
K72 Hepatic failure, not elsewhere classified
0.502 0.498 0.000
H91 Other hearing loss
0.501 0.499 0.000
T75 Effects of other external causes
0.500 0.500 0.000
T74 Maltreatment syndromes
0.500 0.500 0.000
T73 Effects of other deprivation
0.500 0.500 0.000
T70 Effects of air pressure and water pressure
0.500 0.500 0.000
T69 Other effects of reduced temperature
0.500 0.500 0.000
T67 Effects of heat and light
0.500 0.500 0.000
T71 Asphyxiation
0.500 0.500 0.000
T68 Hypothermia
0.500 0.500 0.000
T66 Unspecified effects of radiation
0.500 0.500 0.000
J45 Asthma
0.499 0.501 0.000
E88 Other metabolic disorders
0.498 0.502 0.000
D18.0 Haemangioma, any site
0.498 0.502 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.497 0.502 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.497 0.502 0.000
D46 Myelodysplastic syndromes
0.497 0.502 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.497 0.502 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.497 0.502 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.497 0.502 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.497 0.502 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.497 0.502 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.497 0.502 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.497 0.502 0.000
D45 Polycythaemia vera
0.497 0.502 0.000
D22.9 Melanocytic naevi, unspecified
0.497 0.503 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.497 0.503 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.497 0.503 0.000
S29 Other and unspecified injuries of thorax
0.497 0.503 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.497 0.503 0.000
S27 Injury of other and unspecified intrathoracic organs
0.497 0.503 0.000
S26 Injury of heart
0.497 0.503 0.000
S25 Injury of blood vessels of thorax
0.497 0.503 0.000
S24 Injury of nerves and spinal cord at thorax level
0.497 0.503 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.497 0.503 0.000
S21 Open wound of thorax
0.497 0.503 0.000
S20 Superficial injury of thorax
0.497 0.503 0.000
H52.7 Disorder of refraction, unspecified
0.497 0.503 0.000
H52.6 Other disorders of refraction
0.497 0.503 0.000
H52.5 Disorders of accommodation
0.497 0.503 0.000
H52.4 Presbyopia
0.497 0.503 0.000
H52.2 Astigmatism
0.497 0.503 0.000
H52.0 Hypermetropia
0.497 0.503 0.000
J81 Pulmonary oedema
0.496 0.503 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.495 0.504 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.495 0.504 0.000
S37 Injury of urinary and pelvic organs
0.495 0.504 0.000
S36 Injury of intra-abdominal organs
0.495 0.504 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.495 0.504 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.495 0.504 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.495 0.504 0.000
S31 Open wound of abdomen, lower back and pelvis
0.495 0.504 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.493 0.507 0.000
K22.5 Diverticulum of oesophagus, acquired
0.493 0.507 0.000
K22.3 Perforation of oesophagus
0.493 0.507 0.000
K22.0 Achalasia of cardia
0.493 0.507 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.492 0.508 0.000
Q80-Q89 Other congenital malformations
0.492 0.508 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.492 0.508 0.000
Q60-Q64 Congenital malformations of the urinary system
0.492 0.508 0.000
Q50-Q56 Congenital malformations of genital organs
0.492 0.508 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.492 0.508 0.000
Q35-Q37 Cleft lip and cleft palate
0.492 0.508 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.492 0.508 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.492 0.508 0.000
Q00-Q07 Congenital malformations of the nervous system
0.492 0.508 0.000
H80-H83 Diseases of inner ear
0.492 0.508 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.492 0.508 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.492 0.508 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.491 0.509 0.000
E14 Unspecified diabetes mellitus
0.491 0.509 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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