TreeWAS – Variant ID: rs76617118

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
# Top node	0.997	0.003
Chapter I Certain infectious and parasitic diseases	0.994	0.006
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.994	0.006
M20-M25 Other joint disorders	0.993	0.007
B95-B98 Bacterial, viral and other infectious agents	0.993	0.007
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.991	0.009
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.989	0.011
M50-M54 Other dorsopathies	0.989	0.011
M54 Dorsalgia	0.980	0.020
Chapter II Neoplasms	0.973	0.027
S00-S09 Injuries to the head	0.964	0.036
Chapter XX External causes of morbidity and mortality	0.946	0.054
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.936	0.064
M23 Internal derangement of knee	0.930	0.070
M24 Other specific joint derangements	0.924	0.076
S60-S69 Injuries to the wrist and hand	0.922	0.078
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.922	0.078
C64-C68 Malignant neoplasms of urinary tract	0.912	0.088
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.908	0.092
M54.5 Low back pain	0.896	0.104
M20 Acquired deformities of fingers and toes	0.892	0.108
M54.3 Sciatica	0.890	0.110
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.879	0.121
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.873	0.127
S00 Superficial injury of head	0.872	0.128
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.870	0.130
S66 Injury of muscle and tendon at wrist and hand level	0.868	0.132
Y43 Primarily systemic agents	0.861	0.139
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.859	0.141
C51-C58 Malignant neoplasms of female genital organs	0.858	0.142
D37-D48 Neoplasms of uncertain or unknown behaviour	0.857	0.143
M24.1 Other articular cartilage disorders	0.856	0.144
M54.2 Cervicalgia	0.852	0.148
M20.4 Other hammer toe(s) (acquired)	0.852	0.148
C64 Malignant neoplasm of kidney, except renal pelvis	0.850	0.150
S20-S29 Injuries to the thorax	0.845	0.155
M51 Other intervertebral disk disorders	0.842	0.158
S09 Other and unspecified injuries of head	0.841	0.159
M05-M14 Inflammatory polyarthropathies	0.840	0.160
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.838	0.162
M54.9 Dorsalgia, unspecified	0.837	0.163
M34 Systemic sclerosis	0.835	0.165
M23.2 Derangement of meniscus due to old tear or injury	0.831	0.169
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.828	0.172
M23.8 Other internal derangements of knee	0.825	0.175
M54.56 Low back pain (Lumbar region)	0.822	0.178
Y43.3 Other antineoplastic drugs	0.817	0.183
S01 Open wound of head	0.817	0.183
M54.36 Sciatica (Lumbar region)	0.817	0.183
M45-M49 Spondylopathies	0.814	0.186
B25-B34 Other viral diseases	0.814	0.186
D00-D09 In situ neoplasms	0.810	0.190
M21 Other acquired deformities of limbs	0.807	0.193
D68 Other coagulation defects	0.804	0.196
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.799	0.201
M22 Disorders of patella	0.798	0.202
Y60-Y69 Misadventures to patients during surgical and medical care	0.795	0.205
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.794	0.206
T20-T25 Burns and corrosions of external body surface, specified by site	0.788	0.212
W00-W19 Falls	0.787	0.213
M60-M63 Disorders of muscles	0.787	0.213
B90-B94 Sequelae of infectious and parasitic diseases	0.783	0.217
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.778	0.222
M24.16 Other articular cartilage disorders (Lower leg)	0.778	0.222
S00.1 Contusion of eyelid and periocular area	0.774	0.226
C79 Secondary malignant neoplasm of other sites	0.774	0.226
C80 Malignant neoplasm without specification of site	0.770	0.229
T00-T07 Injuries involving multiple body regions	0.768	0.232
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.766	0.234
C43-C44 Melanoma and other malignant neoplasms of skin	0.762	0.238
M54.57 Low back pain (Lumbosacral region)	0.762	0.238
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.761	0.239
M54.22 Cervicalgia (Cervical region)	0.761	0.239
D50-D53 Nutritional anaemias	0.760	0.240
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.759	0.241
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.757	0.243
M40-M43 Deforming dorsopathies	0.754	0.246
S00.2 Other superficial injuries of eyelid and periocular area	0.751	0.249
S90-S99 Injuries to the ankle and foot	0.750	0.250
Chapter VII Diseases of the eye and adnexa	0.747	0.253
D70-D77 Other diseases of blood and blood-forming organs	0.745	0.255
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.744	0.256
M25 Other joint disorders, not elsewhere classified	0.741	0.259
D68.2 Hereditary deficiency of other clotting factors	0.740	0.260
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.736	0.264
M86-M90 Other osteopathies	0.736	0.264
Chapter XXII Codes for special purposes	0.735	0.265
M47 Spondylosis	0.734	0.266
Y44 Agents primarily affecting blood constituents	0.734	0.266
M24.4 Recurrent dislocation and subluxation of joint	0.734	0.266
A80-A89 Viral infections of the central nervous system	0.733	0.267
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.732	0.268
M80-M85 Disorders of bone density and structure	0.731	0.269
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.731	0.269
C67 Malignant neoplasm of bladder	0.729	0.271
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.727	0.273
S32 Fracture of lumbar spine and pelvis	0.727	0.273
M13 Other arthritis	0.725	0.275
T66-T78 Other and unspecified effects of external causes	0.724	0.276
M54.99 Dorsalgia, unspecified (Site unspecified)	0.724	0.276
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.723	0.276
M54.4 Lumbago with sciatica	0.723	0.277
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.723	0.277
S06 Intracranial injury	0.722	0.278
A30-A49 Other bacterial diseases	0.721	0.279
M34.9 Systemic sclerosis, unspecified	0.721	0.279
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.719	0.280
C54 Malignant neoplasm of corpus uteri	0.719	0.281
S22 Fracture of rib(s), sternum and thoracic spine	0.716	0.284
M91-M94 Chondropathies	0.715	0.285
M00-M03 Infectious arthropathies	0.715	0.285
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285
M23.5 Chronic instability of knee	0.714	0.286
C56 Malignant neoplasm of ovary	0.714	0.286
D69 Purpura and other haemorrhagic conditions	0.714	0.286
M20.2 Hallux rigidus	0.713	0.287
B99-B99 Other infectious diseases	0.713	0.287
B85-B89 Pediculosis, acariasis and other infestations	0.713	0.287
B65-B83 Helminthiases	0.713	0.287
B50-B64 Protozoal diseases	0.713	0.287
B20-B24 Human immunodeficiency virus [HIV] disease	0.713	0.287
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.713	0.287
A75-A79 Rickettsioses	0.713	0.287
A70-A74 Other diseases caused by chlamydiae	0.713	0.287
A65-A69 Other spirochaetal diseases	0.713	0.287
A50-A64 Infections with a predominantly sexual mode of transmission	0.713	0.287
A20-A28 Certain zoonotic bacterial diseases	0.713	0.287
A15-A19 Tuberculosis	0.713	0.287
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.712	0.287
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.712	0.287
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.712	0.287
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.712	0.288
M33 Dermatopolymyositis	0.712	0.288
M32 Systemic lupus erythematosus	0.712	0.288
M30 Polyarteritis nodosa and related conditions	0.712	0.288
S09.8 Other specified injuries of head	0.711	0.289
M54.37 Sciatica (Lumbosacral region)	0.711	0.289
T33-T35 Frostbite	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
T15-T19 Effects of foreign body entering through natural orifice	0.711	0.289
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.711	0.289
S10-S19 Injuries to the neck	0.711	0.289
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.711	0.289
D04 Carcinoma in situ of skin	0.710	0.290
M53 Other dorsopathies, not elsewhere classified	0.709	0.291
M24.11 Other articular cartilage disorders (Shoulder region)	0.705	0.295
S62 Fracture at wrist and hand level	0.705	0.295
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.704	0.296
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.703	0.297
M54.8 Other dorsalgia	0.703	0.297
M54.6 Pain in thoracic spine	0.703	0.297
M54.1 Radiculopathy	0.703	0.297
M54.0 Panniculitis affecting regions of neck and back	0.703	0.297
D80-D89 Certain disorders involving the immune mechanism	0.702	0.298
S50-S59 Injuries to the elbow and forearm	0.701	0.299
X40-X49 Accidental poisoning by and exposure to noxious substances	0.701	0.299
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.701	0.299
T79-T79 Certain early complications of trauma	0.701	0.299
V10-V19 Pedal cyclist injured in transport accident	0.701	0.299
S02 Fracture of skull and facial bones	0.701	0.299
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.700	0.300
M23.80 Other internal derangements of knee (Multiple sites)	0.699	0.300
B15-B19 Viral hepatitis	0.698	0.302
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.698	0.302
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.698	0.302
C40-C41 Malignant neoplasms of bone and articular cartilage	0.698	0.302
S70-S79 Injuries to the hip and thigh	0.697	0.303
S08 Traumatic amputation of part of head	0.691	0.309
S07 Crushing injury of head	0.691	0.309
S05 Injury of eye and orbit	0.691	0.309
S04 Injury of cranial nerves	0.691	0.309
S03 Dislocation, sprain and strain of joints and ligaments of head	0.691	0.309
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.687	0.313
H43-H45 Disorders of vitreous body and globe	0.687	0.313
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.683	0.317
S69 Other and unspecified injuries of wrist and hand	0.683	0.317
V20-V29 Motorcycle rider injured in transport accident	0.681	0.318
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.680	0.320
S09.9 Unspecified injury of head	0.679	0.321
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.678	0.321
Y35-Y36 Legal intervention and operations of war	0.678	0.321
Y10-Y34 Event of undetermined intent	0.678	0.321
Y00-Y09 Assault	0.678	0.321
X85-X99 Assault	0.678	0.321
X58-X59 Accidental exposure to other and unspecified factors	0.678	0.321
X50-X57 Overexertion, travel and privation	0.678	0.321
X30-X39 Exposure to forces of nature	0.678	0.321
X20-X29 Contact with venomous animals and plants	0.678	0.321
X10-X19 Contact with heat and hot substances	0.678	0.321
X00-X09 Exposure to smoke, fire and flames	0.678	0.321
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.678	0.321
W75-W84 Other accidental threats to breathing	0.678	0.321
W65-W74 Accidental drowning and submersion	0.678	0.321
W50-W64 Exposure to animate mechanical forces	0.678	0.321
V98-V99 Other and unspecified transport accidents	0.678	0.321
V95-V97 Air and space transport accidents	0.678	0.321
V90-V94 Water transport accidents	0.678	0.321
V80-V89 Other land transport accidents	0.678	0.321
V70-V79 Bus occupant injured in transport accident	0.678	0.321
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.678	0.321
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.678	0.321
V40-V49 Car occupant injured in transport accident	0.678	0.321
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.678	0.321
V01-V09 Pedestrian injured in transport accident	0.678	0.321
S80-S89 Injuries to the knee and lower leg	0.678	0.322
D47.3 Essential (haemorrhagic) thrombocythaemia	0.676	0.324
Y43.4 Immunosuppressive agents	0.675	0.325
M22.4 Chondromalacia patellae	0.673	0.327
D55-D59 Haemolytic anaemias	0.671	0.329
S61 Open wound of wrist and hand	0.670	0.330
M23.9 Internal derangement of knee, unspecified	0.667	0.333
M23.6 Other spontaneous disruption of ligament(s) of knee	0.667	0.333
M23.4 Loose body in knee	0.667	0.333
M23.1 Discoid meniscus (congenital)	0.667	0.333
M23.0 Cystic meniscus	0.667	0.333
W20-W49 Exposure to inanimate mechanical forces	0.665	0.335
C80.9 Malignant neoplasm, unspecified	0.663	0.336
W19 Unspecified fall	0.663	0.337
M24.9 Joint derangement, unspecified	0.663	0.337
M24.8 Other specific joint derangements, not elsewhere classified	0.663	0.337
M24.7 Protrusio acetabuli	0.663	0.337
M24.6 Ankylosis of joint	0.663	0.337
M24.5 Contracture of joint	0.663	0.337
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.663	0.337
M24.2 Disorder of ligament	0.663	0.337
M24.0 Loose body in joint	0.663	0.337
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.663	0.337
S67 Crushing injury of wrist and hand	0.661	0.339
S65 Injury of blood vessels at wrist and hand level	0.661	0.339
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.661	0.339
S60 Superficial injury of wrist and hand	0.661	0.339
M06 Other rheumatoid arthritis	0.660	0.340
C68 Malignant neoplasm of other and unspecified urinary organs	0.654	0.346
C66 Malignant neoplasm of ureter	0.654	0.346
C65 Malignant neoplasm of renal pelvis	0.654	0.346
C90 Multiple myeloma and malignant plasma cell neoplasms	0.653	0.346
S27 Injury of other and unspecified intrathoracic organs	0.652	0.348
B34 Viral infection of unspecified site	0.652	0.348
Y59 Other and unspecified vaccines and biological substances	0.651	0.349
Y58 Bacterial vaccines	0.651	0.349
Y57 Other and unspecified drugs and medicaments	0.651	0.349
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.651	0.349
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.651	0.349
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.651	0.349
Y53 Agents primarily affecting the gastro-intestinal system	0.651	0.349
Y52 Agents primarily affecting the cardiovascular system	0.651	0.349
Y51 Drugs primarily affecting the autonomic nervous system	0.651	0.349
Y50 Central nervous system stimulants, not elsewhere classified	0.651	0.349
Y49 Psychotropic drugs, not elsewhere classified	0.651	0.349
Y48 Anaesthetics and therapeutic gases	0.651	0.349
Y47 Sedatives, hypnotics and antianxiety drugs	0.651	0.349
Y46 Antiepileptics and anti-Parkinsonism drugs	0.651	0.349
Y41 Other systemic anti-infectives and antiparasitics	0.651	0.349
B97 Viral agents as the cause of diseases classified to other chapters	0.650	0.350
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.650	0.350
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.647	0.353
S00.0 Superficial injury of scalp	0.647	0.353
X60-X84 Intentional self-harm	0.647	0.353
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.646	0.353
H43 Disorders of vitreous body	0.646	0.354
S01.4 Open wound of cheek and temporomandibular area	0.644	0.356
C92 Myeloid leukaemia	0.644	0.356
S64 Injury of nerves at wrist and hand level	0.643	0.357
M47.9 Spondylosis, unspecified	0.643	0.357
T23 Burn and corrosion of wrist and hand	0.643	0.357
M54.55 Low back pain (Thoracolumbar region)	0.643	0.357
M54.54 Low back pain-Thoracic	0.643	0.357
M54.53 Low back pain-Cervicothoracic	0.643	0.357
M54.52 Low back pain-Cervical	0.643	0.357
M54.51 Low back pain-Occipit-atl-axl	0.643	0.357
M54.50 Low back pain (Multiple sites in spine)	0.643	0.357
S01.0 Open wound of scalp	0.640	0.360
M20.3 Other deformity of hallux (acquired)	0.639	0.360
M20.0 Deformity of finger(s)	0.639	0.360
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.639	0.361
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.638	0.362
M54.35 Sciatica (Thoracolumbar region)	0.638	0.362
M54.34 Sciatica-Thoracic	0.638	0.362
M54.33 Sciatica-Cervicothoracic	0.638	0.362
M54.32 Sciatica-Cervical	0.638	0.362
M54.31 Sciatica-Occipit-atl-axl	0.638	0.362
M54.30 Sciatica (Multiple sites in spine)	0.638	0.362
M51.2 Other specified intervertebral disk displacement	0.637	0.363
M51.8 Other specified intervertebral disk disorders	0.637	0.363
M21.3 Wrist or foot drop (acquired)	0.636	0.364
M62 Other disorders of muscle	0.636	0.364
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.635	0.365
C44 Other malignant neoplasms of skin	0.635	0.365
M31 Other necrotising vasculopathies	0.632	0.367
B91 Sequelae of poliomyelitis	0.632	0.368
B25 Cytomegaloviral disease	0.631	0.369
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.631	0.369
C76 Malignant neoplasm of other and ill-defined sites	0.631	0.369
M21.0 Valgus deformity, not elsewhere classified	0.629	0.371
D68.8 Other specified coagulation defects	0.628	0.372
D67 Hereditary factor IX deficiency	0.626	0.374
D66 Hereditary factor VIII deficiency	0.626	0.374
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.626	0.374
S00.7 Multiple superficial injuries of head	0.625	0.375
S00.5 Superficial injury of lip and oral cavity	0.625	0.375
S00.4 Superficial injury of ear	0.625	0.375
S00.3 Superficial injury of nose	0.625	0.375
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.624	0.376
M25.4 Effusion of joint	0.624	0.376
S68 Traumatic amputation of wrist and hand	0.623	0.377
M13.9 Arthritis, unspecified	0.623	0.377
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.622	0.378
S66.8 Injury of other muscles and tendons at wrist and hand level	0.622	0.378
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.622	0.378
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.622	0.378
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.622	0.378
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.622	0.378
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.622	0.378
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.622	0.378
M54.96 Dorsalgia, unspecified (Lumbar region)	0.622	0.378
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.620	0.380
B07 Viral warts	0.619	0.381
C54.1 Endometrium	0.619	0.381
S01.3 Open wound of ear	0.619	0.381
S40-S49 Injuries to the shoulder and upper arm	0.619	0.381
Y43.9 Primarily systemic agent, unspecified	0.618	0.382
Y43.8 Other primarily systemic agents, not elsewhere classified	0.618	0.382
Y43.6 Enzymes, not elsewhere classified	0.618	0.382
Y43.5 Acidifying and alkalising agents	0.618	0.382
Y43.2 Antineoplastic natural products	0.618	0.382
Y43.1 Antineoplastic antimetabolites	0.618	0.382
Y43.0 Antiallergic and antiemetic drugs	0.618	0.382
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.616	0.384
S37 Injury of urinary and pelvic organs	0.616	0.384
S36 Injury of intra-abdominal organs	0.616	0.384
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.616	0.384
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.616	0.384
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.616	0.384
S31 Open wound of abdomen, lower back and pelvis	0.616	0.384
S30 Superficial injury of abdomen, lower back and pelvis	0.616	0.384
S01.2 Open wound of nose	0.616	0.384
C57 Malignant neoplasm of other and unspecified female genital organs	0.615	0.385
C53 Malignant neoplasm of cervix uteri	0.615	0.385
C51 Malignant neoplasm of vulva	0.615	0.385
C58 Malignant neoplasm of placenta	0.615	0.385
C55 Malignant neoplasm of uterus, part unspecified	0.615	0.385
C52 Malignant neoplasm of vagina	0.615	0.385
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.615	0.385
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.615	0.385
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.615	0.385
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.615	0.385
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.615	0.385
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.615	0.385
M24.19 Other articular cartilage disorders (Site unspecified)	0.614	0.386
M24.18 Other articular cartilage disorders (Other)	0.614	0.386
M24.17 Other articular cartilage disorders (Ankle and foot)	0.614	0.386
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.614	0.386
M24.14 Other articular cartilage disorders (Hand)	0.614	0.386
M24.13 Other articular cartilage disorders (Forearm)	0.614	0.386
M24.12 Other articular cartilage disorders (Upper arm)	0.614	0.386
M24.10 Other articular cartilage disorders (Multiple sites)	0.614	0.386
D70 Agranulocytosis	0.613	0.387
M11 Other crystal arthropathies	0.612	0.388
Y86 Sequelae of other accidents	0.612	0.388
C80.0 Malignant neoplasm, primary site unknown, so stated	0.611	0.389
Y40 Systemic antibiotics	0.611	0.389
M54.29 Cervicalgia-Site unspe	0.611	0.389
M54.28 Cervicalgia-Sacral/sacrococ	0.611	0.389
M54.27 Cervicalgia-Lumbosacral	0.611	0.389
M54.26 Cervicalgia-Lumbar	0.611	0.389
M54.25 Cervicalgia-Thoracolumbar	0.611	0.389
M54.24 Cervicalgia-Thoracic	0.611	0.389
M54.23 Cervicalgia (Cervicothoracic region)	0.611	0.389
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.611	0.389
M54.20 Cervicalgia-Mult site	0.611	0.389
S01.9 Open wound of head, part unspecified	0.611	0.389
Y60.0 During surgical operation	0.610	0.390
Y44.2 Anticoagulants	0.610	0.390
Chapter V Mental and behavioural disorders	0.609	0.391
M20.5 Other deformities of toe(s) (acquired)	0.609	0.391
T02 Fractures involving multiple body regions	0.608	0.392
S00.8 Superficial injury of other parts of head	0.608	0.392
M20.6 Acquired deformity of toe(s), unspecified	0.607	0.393
S29 Other and unspecified injuries of thorax	0.606	0.394
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.606	0.394
S26 Injury of heart	0.606	0.394
S25 Injury of blood vessels of thorax	0.606	0.394
S24 Injury of nerves and spinal cord at thorax level	0.606	0.394
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.606	0.394
S21 Open wound of thorax	0.606	0.394
S20 Superficial injury of thorax	0.606	0.394
T31 Burns classified according to extent of body surface involved	0.605	0.395
M51.3 Other specified intervertebral disk degeneration	0.604	0.396
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.604	0.396
M51.9 Intervertebral disk disorder, unspecified	0.604	0.396
M51.4 Schmorl's nodes	0.604	0.396
S09.7 Multiple injuries of head	0.603	0.397
S09.2 Traumatic rupture of ear drum	0.603	0.397
S09.1 Injury of muscle and tendon of head	0.603	0.397
S09.0 Injury of blood vessels of head, not elsewhere classified	0.603	0.397
C01 Malignant neoplasm of base of tongue	0.603	0.397
M14 Arthropathies in other diseases classified elsewhere	0.602	0.397
M12 Other specific arthropathies	0.602	0.397
M09 Juvenile arthritis in diseases classified elsewhere	0.602	0.397
M08 Juvenile arthritis	0.602	0.397
M41 Scoliosis	0.602	0.398
D51 Vitamin B12 deficiency anaemia	0.601	0.399
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.600	0.400
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.600	0.400
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.600	0.400
M54.94 Dorsalgia, unspecified (Thoracic region)	0.600	0.400
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.600	0.400
M54.92 Dorsalgia, unspecified (Cervical region)	0.600	0.400
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.600	0.400
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.600	0.400
H10-H13 Disorders of conjunctiva	0.599	0.401
M50 Cervical disk disorders	0.599	0.401
M34.8 Other forms of systemic sclerosis	0.598	0.401
M34.2 Systemic sclerosis induced by drugs and chemicals	0.598	0.401
M34.1 CR(E)ST syndrome	0.598	0.401
M34.0 Progressive systemic sclerosis	0.598	0.401
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.598	0.402
C79.7 Secondary malignant neoplasm of adrenal gland	0.598	0.402
D06 Carcinoma in situ of cervix uteri	0.598	0.402
D07 Carcinoma in situ of other and unspecified genital organs	0.597	0.402
Chapter IV Endocrine, nutritional and metabolic diseases	0.596	0.404
S01.1 Open wound of eyelid and periocular area	0.596	0.404
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.596	0.404
D41.4 Bladder	0.596	0.404
M54.59 Low back pain (Site unspecified)	0.595	0.405
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.595	0.405
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.594	0.406
C95 Leukaemia of unspecified cell type	0.594	0.406
C94 Other leukaemias of specified cell type	0.594	0.406
C93 Monocytic leukaemia	0.594	0.406
C88 Malignant immunoproliferative diseases	0.594	0.406
C86 Other specified types of T/NK-cell lymphoma	0.594	0.406
C84 Peripheral and cutaneous T-cell lymphomas	0.594	0.406
C81 Hodgkin's disease	0.594	0.406
D04.7 Skin of lower limb, including hip	0.594	0.406
S01.8 Open wound of other parts of head	0.593	0.406
W19.2 School, other institution and public administrative area	0.594	0.406
M23.87 Other internal derangements of knee (Capsular ligament)	0.591	0.409
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.591	0.409
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.591	0.409
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.591	0.409
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.591	0.409
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.591	0.409
C67.9 Bladder, unspecified	0.590	0.410
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.590	0.410
D69.6 Thrombocytopenia, unspecified	0.590	0.410
D46 Myelodysplastic syndromes	0.589	0.411
D50 Iron deficiency anaemia	0.589	0.411
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.587	0.413
D04.6 Skin of upper limb, including shoulder	0.587	0.413
T90 Sequelae of injuries of head	0.586	0.413
S01.7 Multiple open wounds of head	0.586	0.414
M47.2 Other spondylosis with radiculopathy	0.584	0.415
M07 Psoriatic and enteropathic arthropathies	0.584	0.416
M49 Spondylopathies in diseases classified elsewhere	0.584	0.416
B33 Other viral diseases, not elsewhere classified	0.584	0.416
B30 Viral conjunctivitis	0.584	0.416
B27 Infectious mononucleosis	0.584	0.416
B26 Mumps	0.584	0.416
H43.1 Vitreous haemorrhage	0.583	0.417
S22.3 Fracture of rib	0.582	0.417
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.582	0.418
C91 Lymphoid leukaemia	0.581	0.418
D09 Carcinoma in situ of other and unspecified sites	0.581	0.419
D02 Carcinoma in situ of middle ear and respiratory system	0.581	0.419
D01 Carcinoma in situ of other and unspecified digestive organs	0.581	0.419
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.581	0.419
C83 Diffuse non-Hodgkin's lymphoma	0.580	0.420
M05 Seropositive rheumatoid arthritis	0.579	0.421
M21.9 Acquired deformity of limb, unspecified	0.579	0.421
M21.8 Other specified acquired deformities of limbs	0.579	0.421
M21.7 Unequal limb length (acquired)	0.579	0.421
M21.6 Other acquired deformities of ankle and foot	0.579	0.421
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.579	0.421
M21.4 Flat foot [pes planus] (acquired)	0.579	0.421
M21.2 Flexion deformity	0.579	0.421
M21.1 Varus deformity, not elsewhere classified	0.579	0.421
D47.2 Monoclonal gammopathy	0.578	0.421
W13 Fall from, out of or through building or structure	0.578	0.422
S32.1 Fracture of sacrum	0.577	0.423
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.577	0.423
S92 Fracture of foot, except ankle	0.577	0.423
D68.9 Coagulation defect, unspecified	0.576	0.423
D68.6 Other Thrombophilia	0.576	0.423
D68.5 Primary Thrombophilia	0.576	0.423
D68.4 Acquired coagulation factor deficiency	0.576	0.423
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.576	0.423
D68.1 Hereditary factor XI deficiency	0.576	0.423
D68.0 Von Willebrand's disease	0.576	0.423
S06.6 Traumatic subarachnoid haemorrhage	0.575	0.425
M54.39 Sciatica (Site unspecified)	0.573	0.426
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.572	0.428
M22.1 Recurrent subluxation of patella	0.572	0.428
M22.9 Disorder of patella, unspecified	0.572	0.428
M22.3 Other derangements of patella	0.572	0.428
M22.0 Recurrent dislocation of patella	0.572	0.428
M10 Gout	0.570	0.429
Y65 Other misadventures during surgical and medical care	0.570	0.430
Y64 Contaminated medical or biological substances	0.570	0.430

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations