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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76638161
log Bayes Factor = 13.1468
Chromosome 11   position 109,094,318  (GRCh37) Explore rs76638161 on Ensembl!
Variant rs76638161 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
M23 Internal derangement of knee
0.993 0.007 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.986 0.014 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.984 0.016 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
M70-M79 Other soft tissue disorders
0.979 0.021 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.976 0.024 0.000
M45-M49 Spondylopathies
0.974 0.026 0.000
Chapter X Diseases of the respiratory system
0.974 0.026 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.973 0.027 0.000
Chapter V Mental and behavioural disorders
0.972 0.028 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.967 0.033 0.000
M24 Other specific joint derangements
0.963 0.037 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.958 0.042 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.956 0.044 0.000
S60-S69 Injuries to the wrist and hand
0.956 0.044 0.000
Y83.8 Other surgical procedures
0.955 0.045 0.000
I50 Heart failure
0.955 0.045 0.000
M79.8 Other specified soft tissue disorders
0.954 0.046 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.953 0.047 0.000
M80-M85 Disorders of bone density and structure
0.945 0.055 0.000
J40-J47 Chronic lower respiratory diseases
0.941 0.059 0.000
S90-S99 Injuries to the ankle and foot
0.937 0.063 0.000
M25 Other joint disorders, not elsewhere classified
0.935 0.065 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.934 0.066 0.000
S50-S59 Injuries to the elbow and forearm
0.933 0.067 0.000
J47 Bronchiectasis
0.931 0.069 0.000
I25.2 Old myocardial infarction
0.930 0.070 0.000
M79.0 Rheumatism, unspecified
0.929 0.071 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.925 0.075 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.924 0.076 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.922 0.078 0.000
M47 Spondylosis
0.922 0.078 0.000
I20 Angina pectoris
0.921 0.079 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.919 0.081 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.917 0.083 0.000
M24.1 Other articular cartilage disorders
0.917 0.083 0.000
L57.0 Actinic keratosis
0.908 0.092 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.907 0.093 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.902 0.098 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.901 0.099 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.901 0.099 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.901 0.099 0.000
M21 Other acquired deformities of limbs
0.898 0.102 0.000
I20.9 Angina pectoris, unspecified
0.897 0.103 0.000
I51 Complications and ill-defined descriptions of heart disease
0.896 0.104 0.000
M45 Ankylosing spondylitis
0.891 0.109 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.890 0.110 0.000
J09-J18 Influenza and pneumonia
0.888 0.112 0.000
I83 Varicose veins of lower extremities
0.887 0.113 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.882 0.118 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.880 0.120 0.000
M47.9 Spondylosis, unspecified
0.880 0.120 0.000
I72 Other aneurysm
0.880 0.120 0.000
I50.0 Congestive heart failure
0.876 0.124 0.000
S20-S29 Injuries to the thorax
0.875 0.125 0.000
I05-I09 Chronic rheumatic heart diseases
0.875 0.125 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.874 0.126 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.874 0.126 0.000
I50.1 Left ventricular failure
0.868 0.132 0.000
F41 Other anxiety disorders
0.865 0.135 0.000
J45 Asthma
0.863 0.137 0.000
S90 Superficial injury of ankle and foot
0.859 0.141 0.000
I42 Cardiomyopathy
0.857 0.143 0.000
I60-I69 Cerebrovascular diseases
0.856 0.144 0.000
I22 Subsequent myocardial infarction
0.856 0.144 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.851 0.149 0.000
I80 Phlebitis and thrombophlebitis
0.850 0.150 0.000
M25.7 Osteophyte
0.849 0.151 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.849 0.151 0.000
I24 Other acute ischaemic heart diseases
0.843 0.157 0.000
I45 Other conduction disorders
0.840 0.160 0.000
Y84.8 Other medical procedures
0.838 0.162 0.000
M85 Other disorders of bone density and structure
0.835 0.165 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.835 0.165 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.834 0.166 0.000
W20-W49 Exposure to inanimate mechanical forces
0.834 0.166 0.000
Y83.4 Other reconstructive surgery
0.829 0.171 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.828 0.172 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.828 0.172 0.000
M79.1 Myalgia
0.826 0.174 0.000
I35 Nonrheumatic aortic valve disorders
0.822 0.177 0.000
I05 Rheumatic mitral valve diseases
0.816 0.184 0.000
I73 Other peripheral vascular diseases
0.816 0.184 0.000
J45.9 Asthma, unspecified
0.816 0.184 0.000
L60-L75 Disorders of skin appendages
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.813 0.187 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.813 0.187 0.000
J18 Pneumonia, organism unspecified
0.812 0.188 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.810 0.190 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.809 0.191 0.000
S00-S09 Injuries to the head
0.809 0.191 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.808 0.192 0.000
I82 Other venous embolism and thrombosis
0.804 0.196 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.804 0.196 0.000
J00-J06 Acute upper respiratory infections
0.803 0.197 0.000
M86-M90 Other osteopathies
0.803 0.197 0.000
M23.9 Internal derangement of knee, unspecified
0.801 0.199 0.000
I74 Arterial embolism and thrombosis
0.800 0.200 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.799 0.201 0.000
I25.1 Atherosclerotic heart disease
0.798 0.202 0.000
I61 Intracerebral haemorrhage
0.798 0.202 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.795 0.205 0.000
M60-M63 Disorders of muscles
0.794 0.206 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.794 0.206 0.000
S61 Open wound of wrist and hand
0.785 0.215 0.000
I51.7 Cardiomegaly
0.783 0.217 0.000
M81 Osteoporosis without pathological fracture
0.783 0.217 0.000
M22 Disorders of patella
0.782 0.218 0.000
I25.4 Coronary artery aneurysm
0.782 0.218 0.000
S32 Fracture of lumbar spine and pelvis
0.781 0.219 0.000
I25.5 Ischaemic cardiomyopathy
0.780 0.220 0.000
S90.8 Other superficial injuries of ankle and foot
0.779 0.221 0.000
F41.9 Anxiety disorder, unspecified
0.778 0.222 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.777 0.223 0.000
S56 Injury of muscle and tendon at forearm level
0.777 0.223 0.000
M91-M94 Chondropathies
0.775 0.224 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.775 0.225 0.000
I77 Other disorders of arteries and arterioles
0.773 0.227 0.000
I24.8 Other forms of acute ischaemic heart disease
0.772 0.228 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.772 0.228 0.000
S70-S79 Injuries to the hip and thigh
0.772 0.228 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.772 0.228 0.000
M31 Other necrotising vasculopathies
0.772 0.228 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.772 0.228 0.000
F99-F99 Unspecified mental disorder
0.771 0.229 0.000
S52 Fracture of forearm
0.766 0.234 0.000
S10-S19 Injuries to the neck
0.766 0.234 0.000
I72.4 Aneurysm of artery of lower extremity
0.764 0.236 0.000
W50-W64 Exposure to animate mechanical forces
0.763 0.236 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.763 0.237 0.000
F30-F39 Mood [affective] disorders
0.763 0.237 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.762 0.238 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.761 0.238 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.761 0.239 0.000
M23.8 Other internal derangements of knee
0.761 0.239 0.000
S61.8 Open wound of other parts of wrist and hand
0.761 0.239 0.000
M47.8 Other spondylosis
0.759 0.241 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.759 0.241 0.000
E10-E14 Diabetes mellitus
0.759 0.241 0.000
L50-L54 Urticaria and erythema
0.758 0.242 0.000
F43 Reaction to severe stress, and adjustment disorders
0.758 0.242 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.756 0.244 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.756 0.244 0.000
I73.0 Raynaud's syndrome
0.755 0.245 0.000
I87 Other disorders of veins
0.755 0.245 0.000
S50 Superficial injury of forearm
0.754 0.246 0.000
I70 Atherosclerosis
0.753 0.247 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.753 0.247 0.000
F41.1 Generalised anxiety disorder
0.753 0.247 0.000
I85 Oesophageal varices
0.752 0.248 0.000
S92 Fracture of foot, except ankle
0.752 0.248 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.751 0.249 0.000
M40-M43 Deforming dorsopathies
0.748 0.251 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.748 0.252 0.000
I86 Varicose veins of other sites
0.747 0.252 0.000
M79.7 Fibromyalgia
0.746 0.254 0.000
I50.9 Heart failure, unspecified
0.745 0.255 0.000
Chapter VII Diseases of the eye and adnexa
0.745 0.255 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.745 0.255 0.000
S51 Open wound of forearm
0.745 0.255 0.000
I47 Paroxysmal tachycardia
0.744 0.256 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.743 0.257 0.000
I78 Diseases of capillaries
0.742 0.258 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.742 0.258 0.000
J18.9 Pneumonia, unspecified
0.741 0.259 0.000
V40-V49 Car occupant injured in transport accident
0.741 0.259 0.000
M25.77 Osteophyte (Ankle and foot)
0.741 0.259 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.740 0.260 0.000
F42 Obsessive-compulsive disorder
0.739 0.261 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.738 0.262 0.000
I67 Other cerebrovascular diseases
0.737 0.263 0.000
Y84.6 Urinary catheterisation
0.736 0.264 0.000
I05.9 Mitral valve disease, unspecified
0.735 0.265 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.735 0.265 0.000
E14 Unspecified diabetes mellitus
0.733 0.267 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.733 0.267 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.733 0.267 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.732 0.268 0.000
S64 Injury of nerves at wrist and hand level
0.732 0.268 0.000
M25.78 Osteophyte (Other)
0.730 0.270 0.000
Chapter VIII Diseases of the ear and mastoid process
0.730 0.270 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.730 0.270 0.000
M25.9 Joint disorder, unspecified
0.729 0.271 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.728 0.272 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.728 0.272 0.000
F60-F69 Disorders of adult personality and behaviour
0.728 0.272 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.728 0.272 0.000
M84 Disorders of continuity of bone
0.727 0.272 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.727 0.273 0.000
V80-V89 Other land transport accidents
0.726 0.274 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.726 0.274 0.000
M21.0 Valgus deformity, not elsewhere classified
0.725 0.275 0.000
M24.2 Disorder of ligament
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.724 0.276 0.000
M21.3 Wrist or foot drop (acquired)
0.722 0.278 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.721 0.279 0.000
M80 Osteoporosis with pathological fracture
0.721 0.279 0.000
I42.0 Dilated cardiomyopathy
0.721 0.279 0.000
I37 Pulmonary valve disorders
0.719 0.281 0.000
M25.4 Effusion of joint
0.718 0.282 0.000
S67 Crushing injury of wrist and hand
0.718 0.282 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
M85.8 Other specified disorders of bone density and structure
0.717 0.283 0.000
M48 Other spondylopathies
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S01 Open wound of head
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.283 0.000
S91 Open wound of ankle and foot
0.716 0.284 0.000
I46 Cardiac arrest
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.714 0.285 0.000
I25.3 Aneurysm of heart
0.714 0.285 0.000
Y44 Agents primarily affecting blood constituents
0.714 0.286 0.000
W29 Contact with other powered hand tools and household machinery
0.714 0.286 0.000
M50-M54 Other dorsopathies
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
M76 Enthesopathies of lower limb, excluding foot
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.713 0.287 0.000
Chapter VI Diseases of the nervous system
0.713 0.287 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.712 0.288 0.000
M23.5 Chronic instability of knee
0.712 0.288 0.000
M23.1 Discoid meniscus (congenital)
0.712 0.288 0.000
M23.0 Cystic meniscus
0.712 0.288 0.000
M25.8 Other specified joint disorders
0.712 0.288 0.000
W22 Striking against or struck by other objects
0.712 0.288 0.000
M82 Osteoporosis in diseases classified elsewhere
0.711 0.289 0.000
F40 Phobic anxiety disorders
0.710 0.290 0.000
M34 Systemic sclerosis
0.710 0.290 0.000
J20-J22 Other acute lower respiratory infections
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
I35.9 Aortic valve disorder, unspecified
0.709 0.291 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
H53-H54 Visual disturbances and blindness
0.708 0.292 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.707 0.293 0.000
M47.86 Other spondylosis (Lumbar region)
0.707 0.293 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.707 0.293 0.000
S40-S49 Injuries to the shoulder and upper arm
0.706 0.294 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.706 0.294 0.000
S60 Superficial injury of wrist and hand
0.705 0.295 0.000
Chapter I Certain infectious and parasitic diseases
0.705 0.295 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
S69 Other and unspecified injuries of wrist and hand
0.704 0.296 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.702 0.297 0.000
M77 Other enthesopathies
0.702 0.298 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.702 0.298 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.701 0.299 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.701 0.299 0.000
T87 Complications peculiar to reattachment and amputation
0.700 0.299 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.700 0.300 0.000
M79.9 Soft tissue disorder, unspecified
0.699 0.300 0.000
M79.3 Panniculitis, unspecified
0.699 0.300 0.000
M79.2 Neuralgia and neuritis, unspecified
0.699 0.300 0.000
Chapter XXII Codes for special purposes
0.699 0.301 0.000
M49 Spondylopathies in diseases classified elsewhere
0.698 0.301 0.000
J90-J94 Other diseases of pleura
0.699 0.301 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.698 0.302 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.698 0.302 0.000
M23.4 Loose body in knee
0.697 0.303 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.697 0.303 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.697 0.303 0.000
F70-F79 Mental retardation
0.697 0.303 0.000
I05.0 Mitral stenosis
0.697 0.303 0.000
I33 Acute and subacute endocarditis
0.697 0.303 0.000
M71 Other bursopathies
0.696 0.303 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.695 0.305 0.000
I72.3 Aneurysm of iliac artery
0.695 0.305 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.695 0.305 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.695 0.305 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.695 0.305 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.691 0.309 0.000
M24.9 Joint derangement, unspecified
0.691 0.309 0.000
M24.7 Protrusio acetabuli
0.691 0.309 0.000
M24.6 Ankylosis of joint
0.691 0.309 0.000
M24.5 Contracture of joint
0.691 0.309 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.691 0.309 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.690 0.310 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.690 0.310 0.000
I51.0 Cardiac septal defect, acquired
0.689 0.311 0.000
I51.9 Heart disease, unspecified
0.689 0.311 0.000
S20 Superficial injury of thorax
0.687 0.312 0.000
L10-L14 Bullous disorders
0.687 0.313 0.000
I51.8 Other ill-defined heart diseases
0.687 0.313 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.687 0.313 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.687 0.313 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.686 0.314 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.686 0.314 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.685 0.315 0.000
M21.2 Flexion deformity
0.685 0.315 0.000
S65 Injury of blood vessels at wrist and hand level
0.685 0.315 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.685 0.315 0.000
E14.3 With ophthalmic complications
0.685 0.315 0.000
M79.88 Other specified soft tissue disorders (Other)
0.684 0.316 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.684 0.316 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.684 0.316 0.000
I88 Nonspecific lymphadenitis
0.683 0.317 0.000
M21.4 Flat foot [pes planus] (acquired)
0.683 0.317 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.682 0.318 0.000
S32.5 Fracture of pubis
0.681 0.319 0.000
Y83.5 Amputation of limb(s)
0.679 0.321 0.000
M24.0 Loose body in joint
0.678 0.321 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.678 0.322 0.000
M83 Adult osteomalacia
0.677 0.322 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.677 0.323 0.000
J43 Emphysema
0.676 0.324 0.000
S99 Other and unspecified injuries of ankle and foot
0.675 0.325 0.000
J41 Simple and mucopurulent chronic bronchitis
0.675 0.325 0.000
L81 Other disorders of pigmentation
0.675 0.325 0.000
M85.6 Other cyst of bone
0.674 0.326 0.000
J84 Other interstitial pulmonary diseases
0.674 0.326 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.673 0.327 0.000
M79.5 Residual foreign body in soft tissue
0.673 0.327 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.673 0.327 0.000
Y83.0 Surgical operation with transplant of whole organ
0.672 0.328 0.000
S98 Traumatic amputation of ankle and foot
0.672 0.328 0.000
S97 Crushing injury of ankle and foot
0.672 0.328 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.672 0.328 0.000
S95 Injury of blood vessels at ankle and foot level
0.672 0.328 0.000
S94 Injury of nerves at ankle and foot level
0.672 0.328 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.672 0.328 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.670 0.330 0.000
M25.3 Other instability of joint
0.670 0.330 0.000
M25.2 Flail joint
0.670 0.330 0.000
M25.1 Fistula of joint
0.670 0.330 0.000
M25.0 Haemarthrosis
0.670 0.330 0.000
M25.5 Pain in joint
0.670 0.330 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.670 0.330 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.670 0.330 0.000
L58 Radiodermatitis
0.670 0.330 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.670 0.330 0.000
L55 Sunburn
0.670 0.330 0.000
S59 Other and unspecified injuries of forearm
0.669 0.331 0.000
S58 Traumatic amputation of forearm
0.669 0.331 0.000
S57 Crushing injury of forearm
0.669 0.331 0.000
S55 Injury of blood vessels at forearm level
0.669 0.331 0.000
S54 Injury of nerves at forearm level
0.669 0.331 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.669 0.331 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.669 0.331 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.668 0.332 0.000
F20 Schizophrenia
0.668 0.332 0.000
I30 Acute pericarditis
0.668 0.332 0.000
M79.10 Myalgia (Multiple sites)
0.666 0.334 0.000
M79.08 Rheumatism, unspecified (Other)
0.666 0.334 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.666 0.334 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.666 0.334 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.666 0.334 0.000
M79.04 Rheumatism, unspecified (Hand)
0.666 0.334 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.666 0.334 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.666 0.334 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.666 0.334 0.000
M81.4 Drug-induced osteoporosis
0.666 0.334 0.000
I42.9 Cardiomyopathy, unspecified
0.665 0.334 0.000
M86 Osteomyelitis
0.665 0.335 0.000
H53 Visual disturbances
0.665 0.335 0.000
L20-L30 Dermatitis and eczema
0.664 0.336 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.664 0.336 0.000
T86 Failure and rejection of transplanted organs and tissues
0.664 0.336 0.000
F25 Schizoaffective disorders
0.664 0.336 0.000
I72.0 Aneurysm of carotid artery
0.664 0.336 0.000
S52.6 Fracture of lower end of both ulna and radius
0.663 0.337 0.000
F48 Other neurotic disorders
0.663 0.337 0.000
F44 Dissociative [conversion] disorders
0.663 0.337 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.663 0.337 0.000
I45.5 Other specified heart block
0.663 0.337 0.000
I82.8 Embolism and thrombosis of other specified veins
0.663 0.337 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.661 0.339 0.000
M47.1 Other spondylosis with myelopathy
0.661 0.339 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.661 0.339 0.000
I45.3 Trifascicular block
0.659 0.341 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.659 0.341 0.000
I69 Sequelae of cerebrovascular disease
0.658 0.342 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.658 0.342 0.000
L57.5 Actinic granuloma
0.658 0.342 0.000
L57.4 Cutis laxa senilis
0.658 0.342 0.000
L57.3 Poikiloderma of Civatte
0.658 0.342 0.000
L57.2 Cutis rhomboidalis nuchae
0.658 0.342 0.000
L57.1 Actinic reticuloid
0.658 0.342 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.658 0.342 0.000
M24.18 Other articular cartilage disorders (Other)
0.658 0.342 0.000
M24.14 Other articular cartilage disorders (Hand)
0.658 0.342 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.658 0.342 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.658 0.342 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.658 0.342 0.000
L71 Rosacea
0.657 0.342 0.000
I72.8 Aneurysm of other specified arteries
0.657 0.343 0.000
M22.2 Patellofemoral disorders
0.656 0.344 0.000
S27 Injury of other and unspecified intrathoracic organs
0.655 0.344 0.000
I74.8 Embolism and thrombosis of other arteries
0.655 0.345 0.000
I45.9 Conduction disorder, unspecified
0.655 0.345 0.000
E14.9 Without complications
0.654 0.346 0.000
J03 Acute tonsillitis
0.654 0.346 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.653 0.346 0.000
I45.6 Preexcitation syndrome
0.653 0.347 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.652 0.348 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.652 0.348 0.000
Y57 Other and unspecified drugs and medicaments
0.651 0.349 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.651 0.349 0.000
Y59 Other and unspecified vaccines and biological substances
0.650 0.350 0.000
Y58 Bacterial vaccines
0.650 0.350 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.650 0.350 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.650 0.350 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.650 0.350 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.650 0.350 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.650 0.350 0.000
Y48 Anaesthetics and therapeutic gases
0.650 0.350 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.650 0.350 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.650 0.350 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.650 0.350 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.649 0.351 0.000
M62 Other disorders of muscle
0.647 0.353 0.000
I20.0 Unstable angina
0.646 0.354 0.000
Y84.9 Medical procedure, unspecified
0.646 0.354 0.000
Y84.7 Blood-sampling
0.646 0.354 0.000
Y84.5 Insertion of gastric or duodenal sound
0.646 0.354 0.000
Y84.4 Aspiration of fluid
0.646 0.354 0.000
Y84.3 Shock therapy
0.646 0.354 0.000
Y84.1 Kidney dialysis
0.646 0.354 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.646 0.354 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.646 0.354 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.646 0.354 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.646 0.354 0.000
S37 Injury of urinary and pelvic organs
0.646 0.354 0.000
S36 Injury of intra-abdominal organs
0.646 0.354 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.646 0.354 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.646 0.354 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.646 0.354 0.000
S31 Open wound of abdomen, lower back and pelvis
0.646 0.354 0.000
M79.19 Myalgia (Site unspecified)
0.644 0.356 0.000
S61.7 Multiple open wounds of wrist and hand
0.644 0.356 0.000
M21.9 Acquired deformity of limb, unspecified
0.644 0.356 0.000
M21.8 Other specified acquired deformities of limbs
0.644 0.356 0.000
M21.7 Unequal limb length (acquired)
0.644 0.356 0.000
M21.6 Other acquired deformities of ankle and foot
0.644 0.356 0.000
I51.6 Cardiovascular disease, unspecified
0.642 0.358 0.000
I51.5 Myocardial degeneration
0.642 0.358 0.000
I51.4 Myocarditis, unspecified
0.642 0.358 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.642 0.358 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.642 0.358 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.642 0.358 0.000
V10-V19 Pedal cyclist injured in transport accident
0.642 0.358 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.642 0.358 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.642 0.358 0.000
J80 Adult respiratory distress syndrome
0.640 0.360 0.000
T88.4 Failed or difficult intubation
0.640 0.360 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.639 0.361 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.639 0.361 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.639 0.361 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.639 0.361 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.639 0.361 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.639 0.361 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.639 0.361 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.639 0.361 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.639 0.361 0.000
Y83.9 Surgical procedure, unspecified
0.638 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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