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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76660977
log Bayes Factor = 16.2139
Chromosome 1   position 43,042,292  (GRCh37) Explore rs76660977 on Ensembl!
Variant rs76660977 is part of Cluster X0050

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
D00-D09 In situ neoplasms
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.996 0.004 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.994 0.006 0.000
D05 Carcinoma in situ of breast
0.993 0.007 0.000
I50 Heart failure
0.993 0.007 0.000
D05.1 Intraductal carcinoma in situ
0.990 0.010 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.985 0.015 0.000
Chapter X Diseases of the respiratory system
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.981 0.019 0.000
Chapter V Mental and behavioural disorders
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
Z51 Other medical care
0.978 0.022 0.000
Z51.1 Chemotherapy session for neoplasm
0.976 0.024 0.000
I44 Atrioventricular and left bundle-branch block
0.969 0.031 0.000
Chapter I Certain infectious and parasitic diseases
0.968 0.032 0.000
C79 Secondary malignant neoplasm of other sites
0.967 0.033 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.966 0.034 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.965 0.035 0.000
I50.9 Heart failure, unspecified
0.965 0.035 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.964 0.036 0.000
A30-A49 Other bacterial diseases
0.964 0.036 0.000
Chapter VIII Diseases of the ear and mastoid process
0.964 0.036 0.000
J20-J22 Other acute lower respiratory infections
0.962 0.038 0.000
I50.1 Left ventricular failure
0.961 0.039 0.000
A41 Other septicaemia
0.961 0.039 0.000
C77.1 Intrathoracic lymph nodes
0.960 0.040 0.000
C78.7 Secondary malignant neoplasm of liver
0.954 0.046 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.951 0.049 0.000
Z51.5 Palliative care
0.951 0.049 0.000
Y43 Primarily systemic agents
0.951 0.049 0.000
Z51.0 Radiotherapy session
0.948 0.052 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.947 0.053 0.000
J22 Unspecified acute lower respiratory infection
0.947 0.053 0.000
A41.9 Septicaemia, unspecified
0.946 0.054 0.000
Chapter XXI Factors influencing health status and contact with health services
0.946 0.054 0.000
M50-M54 Other dorsopathies
0.945 0.055 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.944 0.056 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.941 0.059 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.940 0.060 0.000
S40-S49 Injuries to the shoulder and upper arm
0.938 0.062 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.937 0.063 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.932 0.068 0.000
Y43.3 Other antineoplastic drugs
0.932 0.068 0.000
C77.3 Axillary and upper limb lymph nodes
0.929 0.071 0.000
D80-D89 Certain disorders involving the immune mechanism
0.928 0.072 0.000
D03 Melanoma in situ
0.926 0.074 0.000
S00-S09 Injuries to the head
0.925 0.075 0.000
T66-T78 Other and unspecified effects of external causes
0.923 0.077 0.000
C77.9 Lymph node, unspecified
0.916 0.084 0.000
I44.0 Atrioventricular block, first degree
0.913 0.087 0.000
I84 Haemorrhoids
0.908 0.092 0.000
C78.0 Secondary malignant neoplasm of lung
0.906 0.094 0.000
M54 Dorsalgia
0.904 0.096 0.000
M05-M14 Inflammatory polyarthropathies
0.899 0.101 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.898 0.102 0.000
S42 Fracture of shoulder and upper arm
0.898 0.102 0.000
I44.7 Left bundle-branch block, unspecified
0.894 0.106 0.000
C34 Malignant neoplasm of bronchus and lung
0.891 0.109 0.000
H65-H75 Diseases of middle ear and mastoid
0.884 0.116 0.000
S70-S79 Injuries to the hip and thigh
0.882 0.118 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.879 0.121 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.878 0.121 0.000
Chapter XI Diseases of the digestive system
0.877 0.123 0.000
Z51.3 Blood transfusion without reported diagnosis
0.874 0.126 0.000
D86 Sarcoidosis
0.874 0.126 0.000
M70-M79 Other soft tissue disorders
0.873 0.127 0.000
I84.6 Residual haemorrhoidal skin tags
0.873 0.127 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.870 0.130 0.000
T78 Adverse effects, not elsewhere classified
0.869 0.131 0.000
C78.2 Secondary malignant neoplasm of pleura
0.861 0.139 0.000
I81 Portal vein thrombosis
0.858 0.142 0.000
M80-M85 Disorders of bone density and structure
0.857 0.143 0.000
S20-S29 Injuries to the thorax
0.856 0.144 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.850 0.150 0.000
Z51.9 Medical care, unspecified
0.849 0.151 0.000
M06 Other rheumatoid arthritis
0.849 0.151 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.848 0.152 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.847 0.153 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.847 0.153 0.000
D70 Agranulocytosis
0.845 0.155 0.000
M54.5 Low back pain
0.845 0.155 0.000
J00-J06 Acute upper respiratory infections
0.843 0.157 0.000
H60-H62 Diseases of external ear
0.841 0.159 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.841 0.159 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.839 0.161 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.834 0.166 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.834 0.166 0.000
S06 Intracranial injury
0.832 0.168 0.000
I86 Varicose veins of other sites
0.830 0.170 0.000
I85 Oesophageal varices
0.829 0.171 0.000
S90-S99 Injuries to the ankle and foot
0.827 0.173 0.000
S42.2 Fracture of upper end of humerus
0.824 0.176 0.000
J90-J94 Other diseases of pleura
0.823 0.177 0.000
I40 Acute myocarditis
0.823 0.177 0.000
K50-K52 Noninfective enteritis and colitis
0.822 0.178 0.000
C77.8 Lymph nodes of multiple regions
0.822 0.178 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.821 0.179 0.000
A41.8 Other specified septicaemia
0.819 0.180 0.000
C50-C50 Malignant neoplasm of breast
0.817 0.183 0.000
I35 Nonrheumatic aortic valve disorders
0.814 0.186 0.000
C77.4 Inguinal and lower limb lymph nodes
0.813 0.187 0.000
I44.6 Other and unspecified fascicular block
0.810 0.190 0.000
M06.9 Rheumatoid arthritis, unspecified
0.808 0.192 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.807 0.193 0.000
F10.1 Harmful use
0.806 0.194 0.000
K90-K93 Other diseases of the digestive system
0.798 0.202 0.000
C80 Malignant neoplasm without specification of site
0.798 0.202 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.792 0.208 0.000
M79.6 Pain in limb
0.791 0.209 0.000
Z40 Prophylactic surgery
0.791 0.209 0.000
H65 Nonsuppurative otitis media
0.784 0.215 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.784 0.216 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.783 0.217 0.000
S80-S89 Injuries to the knee and lower leg
0.782 0.218 0.000
I84.2 Internal haemorrhoids without complication
0.782 0.218 0.000
K70-K77 Diseases of liver
0.782 0.218 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.782 0.218 0.000
Q60-Q64 Congenital malformations of the urinary system
0.781 0.219 0.000
T78.4 Allergy, unspecified
0.781 0.219 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.780 0.220 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.779 0.221 0.000
D86.9 Sarcoidosis, unspecified
0.779 0.221 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.779 0.221 0.000
H90-H95 Other disorders of ear
0.777 0.222 0.000
I87 Other disorders of veins
0.777 0.223 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.776 0.224 0.000
F10.4 Withdrawal state with delirium
0.776 0.224 0.000
I33 Acute and subacute endocarditis
0.776 0.224 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.776 0.224 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.774 0.226 0.000
D37.4 Colon
0.773 0.227 0.000
S42.20 Fracture of upper end of humerus (closed)
0.772 0.228 0.000
M51 Other intervertebral disk disorders
0.771 0.229 0.000
I31 Other diseases of pericardium
0.771 0.229 0.000
I49 Other cardiac arrhythmias
0.771 0.229 0.000
Z42 Follow-up care involving plastic surgery
0.770 0.230 0.000
K50 Crohn's disease [regional enteritis]
0.770 0.230 0.000
I95 Hypotension
0.768 0.232 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.765 0.234 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.765 0.235 0.000
I42 Cardiomyopathy
0.764 0.236 0.000
J95-J99 Other diseases of the respiratory system
0.763 0.237 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.763 0.237 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.763 0.237 0.000
C34.3 Lower lobe, bronchus or lung
0.762 0.238 0.000
M05 Seropositive rheumatoid arthritis
0.761 0.239 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.761 0.239 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.761 0.239 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.760 0.240 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.760 0.240 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.758 0.242 0.000
S10-S19 Injuries to the neck
0.756 0.244 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.756 0.244 0.000
Y52 Agents primarily affecting the cardiovascular system
0.756 0.244 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.753 0.247 0.000
J03 Acute tonsillitis
0.752 0.248 0.000
M54.9 Dorsalgia, unspecified
0.752 0.248 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.751 0.249 0.000
S72 Fracture of femur
0.750 0.250 0.000
M54.56 Low back pain (Lumbar region)
0.749 0.251 0.000
M79.8 Other specified soft tissue disorders
0.749 0.251 0.000
Y43.4 Immunosuppressive agents
0.749 0.251 0.000
S01 Open wound of head
0.749 0.251 0.000
M54.3 Sciatica
0.748 0.252 0.000
A49 Bacterial infection of unspecified site
0.747 0.253 0.000
T78.3 Angioneurotic oedema
0.747 0.253 0.000
C34.9 Bronchus or lung, unspecified
0.747 0.253 0.000
I82 Other venous embolism and thrombosis
0.746 0.254 0.000
S09 Other and unspecified injuries of head
0.746 0.254 0.000
I05-I09 Chronic rheumatic heart diseases
0.745 0.255 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.745 0.255 0.000
C34.1 Upper lobe, bronchus or lung
0.745 0.255 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.744 0.255 0.000
Y43.1 Antineoplastic antimetabolites
0.742 0.258 0.000
X60-X84 Intentional self-harm
0.742 0.258 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.742 0.258 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.741 0.259 0.000
I83 Varicose veins of lower extremities
0.740 0.260 0.000
V40-V49 Car occupant injured in transport accident
0.740 0.260 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.739 0.260 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.739 0.261 0.000
Y95 Nosocomial condition
0.739 0.261 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.738 0.262 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.737 0.263 0.000
S40 Superficial injury of shoulder and upper arm
0.736 0.263 0.000
I36 Nonrheumatic tricuspid valve disorders
0.736 0.264 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.736 0.264 0.000
D04 Carcinoma in situ of skin
0.735 0.264 0.000
M53 Other dorsopathies, not elsewhere classified
0.735 0.265 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.735 0.265 0.000
B99-B99 Other infectious diseases
0.734 0.265 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.734 0.266 0.000
J92 Pleural plaque
0.734 0.266 0.000
M86-M90 Other osteopathies
0.734 0.266 0.000
Z57 Occupational exposure to risk-factors
0.734 0.266 0.000
Y57 Other and unspecified drugs and medicaments
0.733 0.267 0.000
Q80-Q89 Other congenital malformations
0.732 0.268 0.000
H71 Cholesteatoma of middle ear
0.731 0.269 0.000
S42.3 Fracture of shaft of humerus
0.730 0.270 0.000
I35.0 Aortic (valve) stenosis
0.729 0.271 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.727 0.272 0.000
I99 Other and unspecified disorders of circulatory system
0.727 0.273 0.000
K80 Cholelithiasis
0.725 0.275 0.000
S79 Other and unspecified injuries of hip and thigh
0.725 0.275 0.000
I84.1 Internal haemorrhoids with other complications
0.725 0.275 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.724 0.276 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.724 0.276 0.000
M81 Osteoporosis without pathological fracture
0.723 0.277 0.000
M65-M68 Disorders of synovium and tendon
0.722 0.277 0.000
C79.2 Secondary malignant neoplasm of skin
0.722 0.278 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.721 0.279 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.721 0.279 0.000
C81 Hodgkin's disease
0.721 0.279 0.000
M79.67 Pain in limb (Ankle and foot)
0.721 0.279 0.000
D46 Myelodysplastic syndromes
0.721 0.279 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.720 0.280 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.720 0.280 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.719 0.281 0.000
D86.8 Sarcoidosis of other and combined sites
0.719 0.281 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.719 0.281 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.718 0.282 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S42.0 Fracture of clavicle
0.716 0.284 0.000
D09 Carcinoma in situ of other and unspecified sites
0.715 0.284 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.715 0.284 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.715 0.284 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.715 0.284 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.715 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.284 0.000
I48 Atrial fibrillation and flutter
0.715 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.284 0.000
I37 Pulmonary valve disorders
0.715 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.284 0.000
I30 Acute pericarditis
0.715 0.284 0.000
F10.0 Acute intoxication
0.715 0.285 0.000
F17.2 Dependence syndrome
0.715 0.285 0.000
B35-B49 Mycoses
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.713 0.287 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.712 0.287 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.712 0.287 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.712 0.287 0.000
D05.7 Other carcinoma in situ of breast
0.712 0.288 0.000
D05.0 Lobular carcinoma in situ
0.712 0.288 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.711 0.289 0.000
D86.0 Sarcoidosis of lung
0.711 0.289 0.000
D80 Immunodeficiency with predominantly antibody defects
0.710 0.290 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.709 0.291 0.000
S02 Fracture of skull and facial bones
0.707 0.293 0.000
I88 Nonspecific lymphadenitis
0.706 0.294 0.000
Q50-Q56 Congenital malformations of genital organs
0.705 0.295 0.000
Y44 Agents primarily affecting blood constituents
0.705 0.295 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.705 0.295 0.000
K50.9 Crohn's disease, unspecified
0.705 0.295 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.704 0.296 0.000
S92 Fracture of foot, except ankle
0.703 0.297 0.000
M60-M63 Disorders of muscles
0.703 0.297 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.703 0.297 0.000
F80-F89 Disorders of psychological development
0.703 0.297 0.000
F70-F79 Mental retardation
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.702 0.297 0.000
M54.1 Radiculopathy
0.702 0.297 0.000
H60 Otitis externa
0.702 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X50-X57 Overexertion, travel and privation
0.702 0.298 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
W50-W64 Exposure to animate mechanical forces
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V80-V89 Other land transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
F60-F69 Disorders of adult personality and behaviour
0.701 0.298 0.000
Z51.6 Desensitisation to allergens
0.701 0.299 0.000
C15-C26 Malignant neoplasms of digestive organs
0.701 0.299 0.000
M72 Fibroblastic disorders
0.701 0.299 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.701 0.299 0.000
M07 Psoriatic and enteropathic arthropathies
0.700 0.299 0.000
C34.0 Main bronchus
0.700 0.300 0.000
J20 Acute bronchitis
0.700 0.300 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.699 0.301 0.000
I40.0 Infective myocarditis
0.698 0.302 0.000
W00-W19 Falls
0.697 0.303 0.000
J09-J18 Influenza and pneumonia
0.695 0.305 0.000
I44.5 Left posterior fascicular block
0.695 0.305 0.000
I44.4 Left anterior fascicular block
0.695 0.305 0.000
I44.3 Other and unspecified atrioventricular block
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.694 0.306 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.694 0.306 0.000
B65-B83 Helminthiases
0.694 0.306 0.000
B50-B64 Protozoal diseases
0.694 0.306 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.694 0.306 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.694 0.306 0.000
A75-A79 Rickettsioses
0.694 0.306 0.000
A70-A74 Other diseases caused by chlamydiae
0.694 0.306 0.000
A65-A69 Other spirochaetal diseases
0.694 0.306 0.000
A20-A28 Certain zoonotic bacterial diseases
0.694 0.306 0.000
A15-A19 Tuberculosis
0.694 0.306 0.000
C79.6 Secondary malignant neoplasm of ovary
0.693 0.306 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.693 0.306 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.693 0.306 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.693 0.306 0.000
K70 Alcoholic liver disease
0.693 0.307 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.693 0.307 0.000
Y59 Other and unspecified vaccines and biological substances
0.692 0.308 0.000
Y58 Bacterial vaccines
0.692 0.308 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.692 0.308 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.692 0.308 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.692 0.308 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
Y48 Anaesthetics and therapeutic gases
0.692 0.308 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.692 0.308 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.692 0.308 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.692 0.308 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.692 0.308 0.000
C95 Leukaemia of unspecified cell type
0.692 0.308 0.000
C94 Other leukaemias of specified cell type
0.692 0.308 0.000
C93 Monocytic leukaemia
0.692 0.308 0.000
C88 Malignant immunoproliferative diseases
0.692 0.308 0.000
C86 Other specified types of T/NK-cell lymphoma
0.692 0.308 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.692 0.308 0.000
C77.5 Intrapelvic lymph nodes
0.692 0.308 0.000
H61 Other disorders of external ear
0.692 0.308 0.000
D55-D59 Haemolytic anaemias
0.691 0.309 0.000
M91-M94 Chondropathies
0.691 0.309 0.000
A48 Other bacterial diseases, not elsewhere classified
0.691 0.309 0.000
A44 Bartonellosis
0.691 0.309 0.000
A43 Nocardiosis
0.691 0.309 0.000
A42 Actinomycosis
0.691 0.309 0.000
A40 Streptococcal septicaemia
0.691 0.309 0.000
A39 Meningococcal infection
0.691 0.309 0.000
A37 Whooping cough
0.691 0.309 0.000
A36 Diphtheria
0.691 0.309 0.000
A32 Listeriosis
0.691 0.309 0.000
A31 Infection due to other mycobacteria
0.691 0.309 0.000
A30 Leprosy [Hansen's disease]
0.691 0.309 0.000
A46 Erysipelas
0.691 0.309 0.000
A38 Scarlet fever
0.691 0.309 0.000
A35 Other tetanus
0.691 0.309 0.000
A34 Obstetrical tetanus
0.691 0.309 0.000
A33 Tetanus neonatorum
0.691 0.309 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.691 0.309 0.000
J21 Acute bronchiolitis
0.690 0.310 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.690 0.310 0.000
I85.0 Oesophageal varices with bleeding
0.689 0.311 0.000
M79.1 Myalgia
0.689 0.311 0.000
Z41 Procedures for purposes other than remedying health state
0.689 0.311 0.000
A41.4 Septicaemia due to anaerobes
0.689 0.311 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.689 0.311 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.689 0.311 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.687 0.312 0.000
J03.9 Acute tonsillitis, unspecified
0.687 0.313 0.000
B15-B19 Viral hepatitis
0.686 0.313 0.000
S42.1 Fracture of scapula
0.685 0.314 0.000
C50 Malignant neoplasm of breast
0.685 0.315 0.000
M84 Disorders of continuity of bone
0.685 0.315 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.683 0.317 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.682 0.318 0.000
Y43.9 Primarily systemic agent, unspecified
0.682 0.318 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.682 0.318 0.000
Y43.6 Enzymes, not elsewhere classified
0.682 0.318 0.000
Y43.5 Acidifying and alkalising agents
0.682 0.318 0.000
Y43.2 Antineoplastic natural products
0.682 0.318 0.000
Y43.0 Antiallergic and antiemetic drugs
0.682 0.318 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.682 0.318 0.000
V20-V29 Motorcycle rider injured in transport accident
0.681 0.319 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.680 0.320 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.680 0.320 0.000
J60-J70 Lung diseases due to external agents
0.679 0.320 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.679 0.321 0.000
Q35-Q37 Cleft lip and cleft palate
0.679 0.321 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.679 0.321 0.000
Q00-Q07 Congenital malformations of the nervous system
0.679 0.321 0.000
Z63 Other problems related to primary support group, including family circumstances
0.678 0.322 0.000
Z54 Convalescence
0.677 0.323 0.000
Z44 Fitting and adjustment of external prosthetic device
0.677 0.323 0.000
K92 Other diseases of digestive system
0.677 0.323 0.000
F29 Unspecified nonorganic psychosis
0.676 0.324 0.000
H90 Conductive and sensorineural hearing loss
0.676 0.324 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.675 0.325 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.675 0.325 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.675 0.325 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.675 0.325 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.675 0.325 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.674 0.326 0.000
K72 Hepatic failure, not elsewhere classified
0.673 0.327 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.672 0.328 0.000
S48 Traumatic amputation of shoulder and upper arm
0.672 0.328 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.672 0.328 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.672 0.328 0.000
S44 Injury of nerves at shoulder and upper arm level
0.672 0.328 0.000
S41 Open wound of shoulder and upper arm
0.672 0.328 0.000
S47 Crushing injury of shoulder and upper arm
0.672 0.328 0.000
F23 Acute and transient psychotic disorders
0.672 0.328 0.000
I86.4 Gastric varices
0.672 0.328 0.000
Chapter XXII Codes for special purposes
0.672 0.328 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.671 0.328 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.671 0.328 0.000
C32 Malignant neoplasm of larynx
0.671 0.328 0.000
C31 Malignant neoplasm of accessory sinuses
0.671 0.328 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.671 0.328 0.000
C37 Malignant neoplasm of thymus
0.671 0.328 0.000
C33 Malignant neoplasm of trachea
0.671 0.328 0.000
H80-H83 Diseases of inner ear
0.671 0.329 0.000
C80.9 Malignant neoplasm, unspecified
0.670 0.330 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.669 0.331 0.000
I84.4 External haemorrhoids with other complications
0.669 0.331 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.668 0.331 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.668 0.331 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.668 0.331 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.668 0.331 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.668 0.331 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.668 0.331 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.668 0.331 0.000
F11 Mental and behavioural disorders due to use of opioids
0.668 0.331 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.668 0.332 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.668 0.332 0.000
F20 Schizophrenia
0.667 0.333 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.667 0.333 0.000
I86.1 Scrotal varices
0.666 0.334 0.000
K51 Ulcerative colitis
0.666 0.334 0.000
J84 Other interstitial pulmonary diseases
0.666 0.334 0.000
D84 Other immunodeficiencies
0.665 0.335 0.000
D83 Common variable immunodeficiency
0.665 0.335 0.000
D82 Immunodeficiency associated with other major defects
0.665 0.335 0.000
D81 Combined immunodeficiencies
0.665 0.335 0.000
H73 Other disorders of tympanic membrane
0.665 0.335 0.000
W20-W49 Exposure to inanimate mechanical forces
0.664 0.335 0.000
C50.4 Upper-outer quadrant of breast
0.664 0.336 0.000
V10-V19 Pedal cyclist injured in transport accident
0.664 0.336 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.664 0.336 0.000
D03.9 Melanoma in situ, unspecified
0.664 0.336 0.000
D03.8 Melanoma in situ of other sites
0.664 0.336 0.000
D03.5 Melanoma in situ of trunk
0.664 0.336 0.000
D03.4 Melanoma in situ of scalp and neck
0.664 0.336 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.664 0.336 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.664 0.336 0.000
D03.0 Melanoma in situ of lip
0.664 0.336 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.664 0.336 0.000
S08 Traumatic amputation of part of head
0.663 0.337 0.000
S07 Crushing injury of head
0.663 0.337 0.000
S05 Injury of eye and orbit
0.663 0.337 0.000
S04 Injury of cranial nerves
0.663 0.337 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.663 0.337 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.663 0.337 0.000
S06.5 Traumatic subdural haemorrhage
0.662 0.338 0.000
T75 Effects of other external causes
0.662 0.338 0.000
T74 Maltreatment syndromes
0.662 0.338 0.000
T73 Effects of other deprivation
0.662 0.338 0.000
T70 Effects of air pressure and water pressure
0.662 0.338 0.000
T69 Other effects of reduced temperature
0.662 0.338 0.000
T67 Effects of heat and light
0.662 0.338 0.000
T71 Asphyxiation
0.662 0.338 0.000
T68 Hypothermia
0.662 0.338 0.000
T66 Unspecified effects of radiation
0.662 0.338 0.000
Q61 Cystic kidney disease
0.661 0.339 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.660 0.339 0.000
Y40 Systemic antibiotics
0.660 0.340 0.000
H74 Other disorders of middle ear and mastoid
0.659 0.340 0.000
I50.0 Congestive heart failure
0.658 0.342 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.658 0.342 0.000
I47 Paroxysmal tachycardia
0.657 0.343 0.000
S22.0 Fracture of thoracic vertebra
0.657 0.343 0.000
M77 Other enthesopathies
0.657 0.343 0.000
I49.4 Other and unspecified premature depolarisation
0.656 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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