TreeWAS – Variant ID: rs76721197

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter II Neoplasms	0.999	0.001	0.000
M05-M14 Inflammatory polyarthropathies	0.997	0.003	0.000
M13 Other arthritis	0.995	0.005	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.995	0.005	0.000
M13.9 Arthritis, unspecified	0.994	0.006	0.000
S00-S09 Injuries to the head	0.994	0.006	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.991	0.009	0.000
Chapter XX External causes of morbidity and mortality	0.989	0.011	0.000
Chapter V Mental and behavioural disorders	0.981	0.019	0.000
M20-M25 Other joint disorders	0.981	0.019	0.000
M80-M85 Disorders of bone density and structure	0.977	0.023	0.000
Chapter VI Diseases of the nervous system	0.973	0.027	0.000
S00 Superficial injury of head	0.963	0.037	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.963	0.037	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.963	0.037	0.000
C61 Malignant neoplasm of prostate	0.000	0.039	0.961
M81 Osteoporosis without pathological fracture	0.960	0.040	0.000
S60-S69 Injuries to the wrist and hand	0.960	0.040	0.000
Chapter XIV Diseases of the genitourinary system	0.958	0.042	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.956	0.044	0.000
N92 Excessive, frequent and irregular menstruation	0.949	0.051	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.948	0.052	0.000
M81.9 Osteoporosis, unspecified	0.947	0.053	0.000
G30-G32 Other degenerative diseases of the nervous system	0.941	0.059	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.931	0.069	0.000
M25 Other joint disorders, not elsewhere classified	0.926	0.074	0.000
D00-D09 In situ neoplasms	0.925	0.075	0.000
W00-W19 Falls	0.924	0.076	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.922	0.078	0.000
G30 Alzheimer's disease	0.917	0.083	0.000
N92.6 Irregular menstruation, unspecified	0.916	0.084	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.915	0.085	0.000
M13.94 Arthritis, unspecified (Hand)	0.913	0.087	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.912	0.088	0.000
D25 Leiomyoma of uterus	0.912	0.088	0.000
D10-D36 Benign neoplasms	0.911	0.089	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.909	0.091	0.000
D25.9 Leiomyoma of uterus, unspecified	0.906	0.094	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.904	0.096	0.000
N60-N64 Disorders of breast	0.904	0.096	0.000
M20 Acquired deformities of fingers and toes	0.902	0.098	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.897	0.103	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.896	0.104	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.893	0.107	0.000
S00.8 Superficial injury of other parts of head	0.892	0.108	0.000
G30.9 Alzheimer's disease, unspecified	0.892	0.108	0.000
S01 Open wound of head	0.890	0.110	0.000
O60-O75 Complications of labour and delivery	0.890	0.110	0.000
N88 Other noninflammatory disorders of cervix uteri	0.883	0.117	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.882	0.118	0.000
F03 Unspecified dementia	0.876	0.124	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.874	0.126	0.000
T86 Failure and rejection of transplanted organs and tissues	0.874	0.126	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.873	0.127	0.000
G90-G99 Other disorders of the nervous system	0.872	0.128	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.867	0.133	0.000
O42 Premature rupture of membranes	0.862	0.138	0.000
T79-T79 Certain early complications of trauma	0.861	0.139	0.000
C15-C26 Malignant neoplasms of digestive organs	0.860	0.140	0.000
F00 Dementia in Alzheimer's disease	0.859	0.141	0.000
M14 Arthropathies in other diseases classified elsewhere	0.854	0.146	0.000
N60 Benign mammary dysplasia	0.852	0.148	0.000
S90-S99 Injuries to the ankle and foot	0.850	0.150	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.849	0.151	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.845	0.155	0.000
F30-F39 Mood [affective] disorders	0.844	0.156	0.000
C73 Malignant neoplasm of thyroid gland	0.844	0.156	0.000
M20.5 Other deformities of toe(s) (acquired)	0.843	0.157	0.000
S05 Injury of eye and orbit	0.839	0.161	0.000
S00.0 Superficial injury of scalp	0.833	0.166	0.000
M81.98 Osteoporosis, unspecified (Other)	0.832	0.168	0.000
M45-M49 Spondylopathies	0.831	0.169	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.831	0.169	0.000
M25.5 Pain in joint	0.830	0.170	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.830	0.170	0.000
D03 Melanoma in situ	0.830	0.170	0.000
D69 Purpura and other haemorrhagic conditions	0.829	0.171	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.827	0.173	0.000
M20.2 Hallux rigidus	0.825	0.175	0.000
C45 Mesothelioma	0.825	0.175	0.000
S61 Open wound of wrist and hand	0.824	0.176	0.000
M13.98 Arthritis, unspecified (Other)	0.821	0.178	0.000
C60-C63 Malignant neoplasms of male genital organs	0.519	0.180	0.301
C51-C58 Malignant neoplasms of female genital organs	0.820	0.180	0.000
O85-O92 Complications predominantly related to the puerperium	0.818	0.182	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.818	0.182	0.000
W19 Unspecified fall	0.817	0.183	0.000
O42.9 Premature rupture of membranes, unspecified	0.816	0.184	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.815	0.185	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.815	0.185	0.000
S60 Superficial injury of wrist and hand	0.814	0.186	0.000
S50-S59 Injuries to the elbow and forearm	0.813	0.187	0.000
Y43 Primarily systemic agents	0.810	0.190	0.000
D32 Benign neoplasm of meninges	0.809	0.191	0.000
N88.2 Stricture and stenosis of cervix uteri	0.808	0.192	0.000
S06 Intracranial injury	0.807	0.193	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.805	0.195	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.797	0.203	0.000
C34 Malignant neoplasm of bronchus and lung	0.794	0.206	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.794	0.206	0.000
N64 Other disorders of breast	0.793	0.207	0.000
F01 Vascular dementia	0.791	0.209	0.000
Chapter XXII Codes for special purposes	0.790	0.209	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.790	0.210	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.790	0.210	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.790	0.210	0.000
S10-S19 Injuries to the neck	0.789	0.211	0.000
C15 Malignant neoplasm of oesophagus	0.789	0.211	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.788	0.212	0.000
D69.6 Thrombocytopenia, unspecified	0.786	0.214	0.000
V20-V29 Motorcycle rider injured in transport accident	0.786	0.214	0.000
C71 Malignant neoplasm of brain	0.786	0.214	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.786	0.214	0.000
M25.57 Pain in joint (Ankle and foot)	0.784	0.216	0.000
N60.1 Diffuse cystic mastopathy	0.783	0.217	0.000
S69 Other and unspecified injuries of wrist and hand	0.783	0.217	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.781	0.219	0.000
C16 Malignant neoplasm of stomach	0.780	0.220	0.000
S02 Fracture of skull and facial bones	0.779	0.221	0.000
D60-D64 Aplastic and other anaemias	0.778	0.222	0.000
S40-S49 Injuries to the shoulder and upper arm	0.778	0.222	0.000
M24 Other specific joint derangements	0.777	0.223	0.000
M11 Other crystal arthropathies	0.777	0.223	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.776	0.224	0.000
Chapter X Diseases of the respiratory system	0.776	0.224	0.000
M34 Systemic sclerosis	0.773	0.227	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.772	0.227	0.000
O63 Long labour	0.772	0.228	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.772	0.228	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.772	0.228	0.000
S70-S79 Injuries to the hip and thigh	0.771	0.229	0.000
S00.7 Multiple superficial injuries of head	0.771	0.229	0.000
S62 Fracture at wrist and hand level	0.769	0.231	0.000
O36 Maternal care for other known or suspected foetal problems	0.768	0.232	0.000
S01.8 Open wound of other parts of head	0.768	0.232	0.000
D25.0 Submucous leiomyoma of uterus	0.766	0.234	0.000
F31 Bipolar affective disorder	0.765	0.235	0.000
D25.1 Intramural leiomyoma of uterus	0.764	0.236	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.764	0.236	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.763	0.237	0.000
Chapter XI Diseases of the digestive system	0.762	0.238	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.762	0.238	0.000
M25.56 Pain in joint (Lower leg)	0.761	0.239	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.760	0.240	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.760	0.240	0.000
F80-F89 Disorders of psychological development	0.758	0.242	0.000
D04 Carcinoma in situ of skin	0.757	0.243	0.000
K70-K77 Diseases of liver	0.756	0.244	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.755	0.245	0.000
T93 Sequelae of injuries of lower limb	0.755	0.245	0.000
D05 Carcinoma in situ of breast	0.754	0.246	0.000
N60.3 Fibrosclerosis of breast	0.753	0.247	0.000
M14.6 Neuropathic arthropathy	0.752	0.248	0.000
W06 Fall involving bed	0.751	0.249	0.000
D50-D53 Nutritional anaemias	0.751	0.249	0.000
M47 Spondylosis	0.749	0.251	0.000
D25.2 Subserosal leiomyoma of uterus	0.748	0.252	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.748	0.252	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.748	0.252	0.000
V10-V19 Pedal cyclist injured in transport accident	0.748	0.252	0.000
N17-N19 Renal failure	0.748	0.252	0.000
M91-M94 Chondropathies	0.748	0.252	0.000
C32 Malignant neoplasm of larynx	0.746	0.254	0.000
W20-W49 Exposure to inanimate mechanical forces	0.746	0.254	0.000
K70 Alcoholic liver disease	0.746	0.254	0.000
M80 Osteoporosis with pathological fracture	0.745	0.255	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.745	0.255	0.000
S00.9 Superficial injury of head, part unspecified	0.743	0.257	0.000
Y43.3 Other antineoplastic drugs	0.741	0.259	0.000
T86.1 Kidney transplant failure and rejection	0.741	0.259	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.740	0.260	0.000
M31 Other necrotising vasculopathies	0.739	0.261	0.000
G30.0 Alzheimer's disease with early onset	0.739	0.261	0.000
N10-N16 Renal tubulo-interstitial diseases	0.738	0.262	0.000
S01.3 Open wound of ear	0.737	0.263	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.736	0.264	0.000
O00-O08 Pregnancy with abortive outcome	0.736	0.264	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.735	0.265	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.735	0.265	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.733	0.267	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.733	0.267	0.000
N76 Other inflammation of vagina and vulva	0.732	0.268	0.000
G60 Hereditary and idiopathic neuropathy	0.732	0.268	0.000
C50-C50 Malignant neoplasm of breast	0.732	0.268	0.000
T81 Complications of procedures, not elsewhere classified	0.730	0.270	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.729	0.271	0.000
N72 Inflammatory disease of cervix uteri	0.728	0.272	0.000
M25.8 Other specified joint disorders	0.728	0.272	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.727	0.273	0.000
C45.0 Mesothelioma of pleura	0.727	0.273	0.000
X50-X57 Overexertion, travel and privation	0.726	0.273	0.000
T87 Complications peculiar to reattachment and amputation	0.724	0.276	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.723	0.277	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.723	0.277	0.000
N86 Erosion and ectropion of cervix uteri	0.721	0.279	0.000
S64 Injury of nerves at wrist and hand level	0.721	0.279	0.000
S01.4 Open wound of cheek and temporomandibular area	0.721	0.279	0.000
C56 Malignant neoplasm of ovary	0.719	0.281	0.000
N61 Inflammatory disorders of breast	0.719	0.281	0.000
G70-G73 Diseases of myoneural junction and muscle	0.718	0.282	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.717	0.283	0.000
D68 Other coagulation defects	0.717	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.284	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.715	0.285	0.000
M12 Other specific arthropathies	0.715	0.285	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.715	0.285	0.000
M08 Juvenile arthritis	0.715	0.285	0.000
K70.9 Alcoholic liver disease, unspecified	0.715	0.285	0.000
M47.8 Other spondylosis	0.714	0.286	0.000
S92 Fracture of foot, except ankle	0.714	0.286	0.000
M25.4 Effusion of joint	0.714	0.286	0.000
M13.8 Other specified arthritis	0.714	0.286	0.000
M13.1 Monoarthritis, not elsewhere classified	0.714	0.286	0.000
M13.0 Polyarthritis, unspecified	0.714	0.286	0.000
M13.93 Arthritis, unspecified (Forearm)	0.713	0.287	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.713	0.287	0.000
S08 Traumatic amputation of part of head	0.713	0.287	0.000
S07 Crushing injury of head	0.713	0.287	0.000
S04 Injury of cranial nerves	0.713	0.287	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.713	0.287	0.000
S01.0 Open wound of scalp	0.713	0.287	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.713	0.287	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.713	0.287	0.000
D32.0 Cerebral meninges	0.712	0.288	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.711	0.289	0.000
M86-M90 Other osteopathies	0.711	0.289	0.000
D55-D59 Haemolytic anaemias	0.711	0.289	0.000
S67 Crushing injury of wrist and hand	0.711	0.289	0.000
Y35-Y36 Legal intervention and operations of war	0.709	0.291	0.000
Y10-Y34 Event of undetermined intent	0.709	0.291	0.000
Y00-Y09 Assault	0.709	0.291	0.000
X85-X99 Assault	0.709	0.291	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.709	0.291	0.000
X30-X39 Exposure to forces of nature	0.709	0.291	0.000
X20-X29 Contact with venomous animals and plants	0.709	0.291	0.000
X10-X19 Contact with heat and hot substances	0.709	0.291	0.000
X00-X09 Exposure to smoke, fire and flames	0.709	0.291	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.709	0.291	0.000
W75-W84 Other accidental threats to breathing	0.709	0.291	0.000
W65-W74 Accidental drowning and submersion	0.709	0.291	0.000
W50-W64 Exposure to animate mechanical forces	0.709	0.291	0.000
V98-V99 Other and unspecified transport accidents	0.709	0.291	0.000
V95-V97 Air and space transport accidents	0.709	0.291	0.000
V90-V94 Water transport accidents	0.709	0.291	0.000
V80-V89 Other land transport accidents	0.709	0.291	0.000
V70-V79 Bus occupant injured in transport accident	0.709	0.291	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.709	0.291	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.709	0.291	0.000
V40-V49 Car occupant injured in transport accident	0.709	0.291	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.709	0.291	0.000
V01-V09 Pedestrian injured in transport accident	0.709	0.291	0.000
W17 Other fall from one level to another	0.708	0.291	0.000
M00-M03 Infectious arthropathies	0.707	0.292	0.000
S50 Superficial injury of forearm	0.707	0.293	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.706	0.294	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.706	0.294	0.000
D16 Benign neoplasm of bone and articular cartilage	0.705	0.295	0.000
C16.9 Stomach, unspecified	0.705	0.295	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.704	0.296	0.000
F70-F79 Mental retardation	0.704	0.296	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.703	0.297	0.000
M33 Dermatopolymyositis	0.703	0.297	0.000
M32 Systemic lupus erythematosus	0.703	0.297	0.000
M30 Polyarteritis nodosa and related conditions	0.703	0.297	0.000
T66-T78 Other and unspecified effects of external causes	0.703	0.297	0.000
M21 Other acquired deformities of limbs	0.703	0.297	0.000
N87 Dysplasia of cervix uteri	0.703	0.297	0.000
X60-X84 Intentional self-harm	0.702	0.298	0.000
M07 Psoriatic and enteropathic arthropathies	0.701	0.299	0.000
M83 Adult osteomalacia	0.700	0.300	0.000
M82 Osteoporosis in diseases classified elsewhere	0.700	0.300	0.000
M22 Disorders of patella	0.700	0.300	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.699	0.301	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.698	0.302	0.000
F60-F69 Disorders of adult personality and behaviour	0.697	0.303	0.000
O80-O84 Delivery	0.697	0.303	0.000
M84 Disorders of continuity of bone	0.696	0.304	0.000
O41 Other disorders of amniotic fluid and membranes	0.696	0.304	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.696	0.304	0.000
D09 Carcinoma in situ of other and unspecified sites	0.695	0.305	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.695	0.305	0.000
F99-F99 Unspecified mental disorder	0.694	0.306	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.694	0.306	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.694	0.306	0.000
M40-M43 Deforming dorsopathies	0.694	0.306	0.000
M81.4 Drug-induced osteoporosis	0.693	0.307	0.000
N60.2 Fibroadenosis of breast	0.693	0.307	0.000
K90-K93 Other diseases of the digestive system	0.692	0.308	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.692	0.308	0.000
S00.5 Superficial injury of lip and oral cavity	0.691	0.309	0.000
S00.4 Superficial injury of ear	0.691	0.309	0.000
S00.3 Superficial injury of nose	0.691	0.309	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.690	0.310	0.000
T90 Sequelae of injuries of head	0.690	0.310	0.000
N99-N99 Other disorders of the genitourinary system	0.690	0.310	0.000
O63.9 Long labour, unspecified	0.690	0.310	0.000
O48 Prolonged pregnancy	0.689	0.311	0.000
G93 Other disorders of brain	0.689	0.311	0.000
G90 Disorders of autonomic nervous system	0.689	0.311	0.000
D24 Benign neoplasm of breast	0.688	0.311	0.000
M81.8 Other osteoporosis	0.688	0.312	0.000
M81.6 Localised osteoporosis [Lequesne]	0.688	0.312	0.000
M81.5 Idiopathic osteoporosis	0.688	0.312	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.688	0.312	0.000
M81.2 Osteoporosis of disuse	0.688	0.312	0.000
M81.1 Postoophorectomy osteoporosis	0.688	0.312	0.000
M81.0 Postmenopausal osteoporosis	0.688	0.312	0.000
S65 Injury of blood vessels at wrist and hand level	0.688	0.312	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.688	0.312	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.687	0.313	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.685	0.315	0.000
F02 Dementia in other diseases classified elsewhere	0.685	0.315	0.000
F09 Unspecified organic or symptomatic mental disorder	0.685	0.315	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.685	0.315	0.000
Chapter VIII Diseases of the ear and mastoid process	0.685	0.315	0.000
D80-D89 Certain disorders involving the immune mechanism	0.684	0.316	0.000
C15.5 Lower third of oesophagus	0.684	0.316	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.683	0.317	0.000
F33 Recurrent depressive disorder	0.682	0.317	0.000
C45.7 Mesothelioma of other sites	0.682	0.318	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.682	0.318	0.000
W08 Fall involving other furniture	0.682	0.318	0.000
W07 Fall involving chair	0.681	0.319	0.000
N92.5 Other specified irregular menstruation	0.680	0.320	0.000
N92.2 Excessive menstruation at puberty	0.680	0.320	0.000
N00-N08 Glomerular diseases	0.680	0.320	0.000
N98 Complications associated with artificial fertilisation	0.679	0.320	0.000
N91 Absent, scanty and rare menstruation	0.679	0.320	0.000
N82 Fistulae involving female genital tract	0.679	0.320	0.000
N96 Habitual aborter	0.679	0.320	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.679	0.321	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.679	0.321	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.679	0.321	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.679	0.321	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.679	0.321	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.679	0.321	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.678	0.322	0.000
N92.3 Ovulation bleeding	0.677	0.322	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.676	0.323	0.000
O40 Polyhydramnios	0.676	0.324	0.000
K92 Other diseases of digestive system	0.676	0.324	0.000
S61.0 Open wound of finger(s) without damage to nail	0.676	0.324	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.675	0.325	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.675	0.325	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.675	0.325	0.000
F01.9 Vascular dementia, unspecified	0.673	0.327	0.000
M65-M68 Disorders of synovium and tendon	0.672	0.328	0.000
N90.5 Atrophy of vulva	0.672	0.328	0.000
D50 Iron deficiency anaemia	0.672	0.328	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.671	0.329	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.671	0.329	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.671	0.329	0.000
M25.9 Joint disorder, unspecified	0.670	0.330	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.670	0.330	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.670	0.330	0.000
D26 Other benign neoplasms of uterus	0.670	0.330	0.000
Chapter VII Diseases of the eye and adnexa	0.669	0.331	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.669	0.331	0.000
J95-J99 Other diseases of the respiratory system	0.669	0.331	0.000
K76 Other diseases of liver	0.669	0.331	0.000
C34.0 Main bronchus	0.669	0.331	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.668	0.332	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.667	0.333	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.667	0.333	0.000
C21 Malignant neoplasm of anus and anal canal	0.667	0.333	0.000
O70 Perineal laceration during delivery	0.667	0.333	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.667	0.333	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.666	0.334	0.000
N89 Other noninflammatory disorders of vagina	0.666	0.334	0.000
C34.1 Upper lobe, bronchus or lung	0.666	0.334	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.665	0.335	0.000
S61.7 Multiple open wounds of wrist and hand	0.665	0.335	0.000
M25.3 Other instability of joint	0.664	0.336	0.000
M25.2 Flail joint	0.664	0.336	0.000
M25.1 Fistula of joint	0.664	0.336	0.000
M25.0 Haemarthrosis	0.664	0.336	0.000
O44 Placenta praevia	0.664	0.336	0.000
G60.0 Hereditary motor and sensory neuropathy	0.663	0.336	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.663	0.337	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.663	0.337	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.663	0.337	0.000
O66 Other obstructed labour	0.662	0.337	0.000
W13 Fall from, out of or through building or structure	0.662	0.338	0.000
W18 Other fall on same level	0.662	0.338	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.662	0.338	0.000
W15 Fall from cliff	0.662	0.338	0.000
W14 Fall from tree	0.662	0.338	0.000
W12 Fall on and from scaffolding	0.662	0.338	0.000
W11 Fall on and from ladder	0.662	0.338	0.000
W10 Fall on and from stairs and steps	0.662	0.338	0.000
W09 Fall involving playground equipment	0.662	0.338	0.000
W05 Fall involving wheelchair	0.662	0.338	0.000
W04 Fall while being carried or supported by other persons	0.662	0.338	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.662	0.338	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.662	0.338	0.000
W00 Fall on same level involving ice and snow	0.662	0.338	0.000
O43 Placental disorders	0.662	0.338	0.000
D34 Benign neoplasm of thyroid gland	0.662	0.338	0.000
M85 Other disorders of bone density and structure	0.661	0.339	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.661	0.339	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.661	0.339	0.000
N64.5 Other signs and symptoms in breast	0.660	0.340	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.660	0.340	0.000
S99 Other and unspecified injuries of ankle and foot	0.659	0.340	0.000
K92.1 Melaena	0.659	0.341	0.000
M05 Seropositive rheumatoid arthritis	0.658	0.342	0.000
S60.8 Other superficial injuries of wrist and hand	0.658	0.342	0.000
G30.8 Other Alzheimer's disease	0.657	0.343	0.000
G30.1 Alzheimer's disease with late onset	0.657	0.343	0.000
T98 Sequelae of other and unspecified effects of external causes	0.657	0.343	0.000
S69.9 Unspecified injury of wrist and hand	0.656	0.344	0.000
S05.8 Other injuries of eye and orbit	0.655	0.345	0.000
J90-J94 Other diseases of pleura	0.654	0.346	0.000
M24.2 Disorder of ligament	0.654	0.346	0.000
O45 Premature separation of placenta [abruptio placentae]	0.654	0.346	0.000
O33 Maternal care for known or suspected disproportion	0.654	0.346	0.000
O31 Complications specific to multiple gestation	0.654	0.346	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.653	0.347	0.000
M47.86 Other spondylosis (Lumbar region)	0.653	0.347	0.000
D31 Benign neoplasm of eye and adnexa	0.653	0.347	0.000
D30 Benign neoplasm of urinary organs	0.653	0.347	0.000
D29 Benign neoplasm of male genital organs	0.653	0.347	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.653	0.347	0.000
D19 Benign neoplasm of mesothelial tissue	0.653	0.347	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.653	0.347	0.000
N17 Acute renal failure	0.653	0.347	0.000
S00.1 Contusion of eyelid and periocular area	0.652	0.347	0.000
O36.8 Maternal care for other specified foetal problems	0.652	0.347	0.000
S80-S89 Injuries to the knee and lower leg	0.652	0.348	0.000
H30-H36 Disorders of choroid and retina	0.652	0.348	0.000
O16 Unspecified maternal hypertension	0.652	0.348	0.000
M20.3 Other deformity of hallux (acquired)	0.652	0.348	0.000
N81 Female genital prolapse	0.652	0.348	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.651	0.348	0.000
C74 Malignant neoplasm of adrenal gland	0.651	0.348	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.651	0.349	0.000
H35 Other retinal disorders	0.650	0.350	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.650	0.350	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.650	0.350	0.000
O86 Other puerperal infections	0.650	0.350	0.000
O61 Failed induction of labour	0.649	0.351	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.649	0.351	0.000
C15.9 Oesophagus, unspecified	0.648	0.351	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.648	0.352	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.648	0.352	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.648	0.352	0.000
C31 Malignant neoplasm of accessory sinuses	0.648	0.352	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.648	0.352	0.000
C37 Malignant neoplasm of thymus	0.648	0.352	0.000
C33 Malignant neoplasm of trachea	0.648	0.352	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.648	0.352	0.000
C71.9 Brain, unspecified	0.648	0.352	0.000
F20 Schizophrenia	0.647	0.353	0.000
S01.2 Open wound of nose	0.647	0.353	0.000
W19.1 Residential institution	0.646	0.354	0.000
V27 Motorcycle rider injured in collision with fixed or stationary object	0.645	0.355	0.000
D61 Other aplastic anaemias	0.644	0.356	0.000
O87 Venous complications in the puerperium	0.644	0.356	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.644	0.356	0.000
W19.4 Street and highway	0.644	0.356	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.643	0.357	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.643	0.357	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.643	0.357	0.000
C46 Kaposi's sarcoma	0.643	0.357	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.643	0.357	0.000
D05.0 Lobular carcinoma in situ	0.643	0.357	0.000
D67 Hereditary factor IX deficiency	0.643	0.357	0.000
D66 Hereditary factor VIII deficiency	0.643	0.357	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.643	0.357	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.642	0.358	0.000
W19.2 School, other institution and public administrative area	0.642	0.358	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.642	0.358	0.000
G40-G47 Episodic and paroxysmal disorders	0.641	0.359	0.000
S09 Other and unspecified injuries of head	0.641	0.359	0.000
S68 Traumatic amputation of wrist and hand	0.641	0.359	0.000
Y59 Other and unspecified vaccines and biological substances	0.641	0.359	0.000
Y58 Bacterial vaccines	0.641	0.359	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.641	0.359	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.641	0.359	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.641	0.359	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.641	0.359	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.641	0.359	0.000
Y48 Anaesthetics and therapeutic gases	0.641	0.359	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.641	0.359	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.641	0.359	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.641	0.359	0.000
O30 Multiple gestation	0.640	0.360	0.000
O36.6 Maternal care for excessive foetal growth	0.640	0.360	0.000
H35.3 Degeneration of macula and posterior pole	0.640	0.360	0.000
Q80-Q89 Other congenital malformations	0.640	0.360	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations