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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77053667
log Bayes Factor = 7.61983
Chromosome 2   position 106,646,550  (GRCh37) Explore rs77053667 on Ensembl!
Variant rs77053667 is part of Cluster X0218

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.998 0.002 0.000
I26 Pulmonary embolism
0.997 0.003 0.000
C64-C68 Malignant neoplasms of urinary tract
0.996 0.004 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.996 0.004 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.995 0.005 0.000
G40-G47 Episodic and paroxysmal disorders
0.995 0.005 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.994 0.006 0.000
C67 Malignant neoplasm of bladder
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.989 0.011 0.000
C67.9 Bladder, unspecified
0.987 0.013 0.000
G40 Epilepsy
0.986 0.014 0.000
Q60-Q64 Congenital malformations of the urinary system
0.983 0.017 0.000
G30-G32 Other degenerative diseases of the nervous system
0.973 0.027 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.970 0.030 0.000
G40.9 Epilepsy, unspecified
0.970 0.030 0.000
Q61 Cystic kidney disease
0.968 0.032 0.000
G90-G99 Other disorders of the nervous system
0.963 0.037 0.000
Chapter VIII Diseases of the ear and mastoid process
0.948 0.052 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.945 0.055 0.000
I10-I15 Hypertensive diseases
0.942 0.058 0.000
D46 Myelodysplastic syndromes
0.936 0.064 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.922 0.078 0.000
T66-T78 Other and unspecified effects of external causes
0.922 0.078 0.000
G70-G73 Diseases of myoneural junction and muscle
0.917 0.083 0.000
H65-H75 Diseases of middle ear and mastoid
0.916 0.084 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.909 0.091 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.908 0.092 0.000
I85 Oesophageal varices
0.903 0.097 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.903 0.097 0.000
Chapter XX External causes of morbidity and mortality
0.903 0.097 0.000
Q61.0 Congenital single renal cyst
0.901 0.099 0.000
Q61.2 Polycystic kidney, adult type
0.901 0.099 0.000
I80 Phlebitis and thrombophlebitis
0.900 0.100 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.900 0.100 0.000
Chapter V Mental and behavioural disorders
0.899 0.101 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.888 0.112 0.000
H72 Perforation of tympanic membrane
0.887 0.113 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.883 0.117 0.000
I83 Varicose veins of lower extremities
0.882 0.118 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.881 0.119 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.880 0.120 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.880 0.120 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.875 0.125 0.000
I10 Essential (primary) hypertension
0.865 0.135 0.000
C67.2 Lateral wall of bladder
0.864 0.136 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.862 0.138 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.860 0.140 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.854 0.146 0.000
G93 Other disorders of brain
0.854 0.146 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.849 0.151 0.000
D45 Polycythaemia vera
0.848 0.151 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.848 0.152 0.000
T78 Adverse effects, not elsewhere classified
0.847 0.153 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.846 0.154 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.845 0.155 0.000
Q50-Q56 Congenital malformations of genital organs
0.839 0.161 0.000
C67.4 Posterior wall of bladder
0.835 0.165 0.000
I95 Hypotension
0.834 0.166 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.829 0.171 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.828 0.172 0.000
G72 Other myopathies
0.828 0.172 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.826 0.174 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.818 0.182 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.816 0.184 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.815 0.185 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.812 0.188 0.000
I85.9 Oesophageal varices without bleeding
0.808 0.192 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.808 0.192 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.806 0.194 0.000
Q80-Q89 Other congenital malformations
0.805 0.195 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.803 0.197 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.803 0.197 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.802 0.198 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.802 0.198 0.000
C65 Malignant neoplasm of renal pelvis
0.800 0.200 0.000
C73 Malignant neoplasm of thyroid gland
0.800 0.200 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.799 0.201 0.000
V80-V89 Other land transport accidents
0.799 0.201 0.000
C66 Malignant neoplasm of ureter
0.797 0.203 0.000
I30-I52 Other forms of heart disease
0.795 0.205 0.000
Q61.3 Polycystic kidney, unspecified
0.794 0.206 0.000
S20-S29 Injuries to the thorax
0.793 0.207 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.792 0.208 0.000
I12 Hypertensive renal disease
0.792 0.208 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.792 0.208 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.790 0.210 0.000
G96 Other disorders of central nervous system
0.787 0.213 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.786 0.214 0.000
C81 Hodgkin's disease
0.785 0.215 0.000
G91 Hydrocephalus
0.784 0.216 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.782 0.218 0.000
D46.2 Refractory anaemia with excess of blasts
0.781 0.219 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.780 0.220 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.779 0.221 0.000
G30 Alzheimer's disease
0.779 0.221 0.000
S00-S09 Injuries to the head
0.777 0.223 0.000
Q63 Other congenital malformations of kidney
0.776 0.224 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.776 0.224 0.000
G93.6 Cerebral oedema
0.775 0.225 0.000
I85.0 Oesophageal varices with bleeding
0.775 0.225 0.000
T79-T79 Certain early complications of trauma
0.774 0.226 0.000
G40.8 Other epilepsy
0.773 0.227 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.772 0.228 0.000
T36 Poisoning by systemic antibiotics
0.771 0.229 0.000
F99-F99 Unspecified mental disorder
0.769 0.231 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.768 0.232 0.000
C67.5 Bladder neck
0.766 0.234 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.765 0.235 0.000
I95.9 Hypotension, unspecified
0.765 0.235 0.000
D40.0 Prostate
0.763 0.237 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.763 0.237 0.000
I34 Nonrheumatic mitral valve disorders
0.763 0.237 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.762 0.238 0.000
T46.1 Calcium-channel blockers
0.761 0.239 0.000
H60-H62 Diseases of external ear
0.760 0.240 0.000
H72.0 Central perforation of tympanic membrane
0.759 0.240 0.000
I35 Nonrheumatic aortic valve disorders
0.759 0.241 0.000
S90-S99 Injuries to the ankle and foot
0.758 0.242 0.000
F60-F69 Disorders of adult personality and behaviour
0.757 0.243 0.000
I28 Other diseases of pulmonary vessels
0.756 0.244 0.000
S10-S19 Injuries to the neck
0.756 0.244 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.756 0.244 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.756 0.244 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.756 0.244 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.754 0.246 0.000
I15 Secondary hypertension
0.754 0.246 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.754 0.246 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.753 0.247 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.752 0.248 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.749 0.251 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.747 0.253 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.746 0.254 0.000
G47 Sleep disorders
0.746 0.254 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.744 0.255 0.000
G41 Status epilepticus
0.742 0.258 0.000
X20-X29 Contact with venomous animals and plants
0.742 0.258 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.741 0.259 0.000
T00-T07 Injuries involving multiple body regions
0.740 0.260 0.000
G90 Disorders of autonomic nervous system
0.740 0.260 0.000
W20-W49 Exposure to inanimate mechanical forces
0.739 0.261 0.000
T18 Foreign body in alimentary tract
0.738 0.262 0.000
I34.1 Mitral (valve) prolapse
0.735 0.265 0.000
G45.4 Transient global amnesia
0.734 0.266 0.000
I95.2 Hypotension due to drugs
0.733 0.267 0.000
T40.4 Other synthetic narcotics
0.731 0.269 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.730 0.270 0.000
G93.0 Cerebral cysts
0.729 0.271 0.000
G72.9 Myopathy, unspecified
0.728 0.272 0.000
T21 Burn and corrosion of trunk
0.725 0.275 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.724 0.276 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.722 0.278 0.000
H66 Suppurative and unspecified otitis media
0.721 0.279 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.721 0.279 0.000
G45.3 Amaurosis fugax
0.719 0.281 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.718 0.282 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.718 0.282 0.000
G31.8 Other specified degenerative diseases of nervous system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C51-C58 Malignant neoplasms of female genital organs
0.716 0.284 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
H80-H83 Diseases of inner ear
0.716 0.284 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.284 0.000
T93 Sequelae of injuries of lower limb
0.715 0.285 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.714 0.285 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.714 0.286 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.713 0.286 0.000
I60-I69 Cerebrovascular diseases
0.713 0.287 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.713 0.287 0.000
Q35-Q37 Cleft lip and cleft palate
0.713 0.287 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
C67.8 Overlapping lesion of bladder
0.712 0.288 0.000
C67.7 Urachus
0.712 0.288 0.000
C67.0 Trigone of bladder
0.712 0.288 0.000
I44 Atrioventricular and left bundle-branch block
0.711 0.289 0.000
T70 Effects of air pressure and water pressure
0.710 0.290 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.709 0.291 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.291 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.709 0.291 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.709 0.291 0.000
I86 Varicose veins of other sites
0.709 0.291 0.000
G71 Primary disorders of muscles
0.707 0.292 0.000
H72.8 Other perforations of tympanic membrane
0.707 0.293 0.000
G40.5 Special epileptic syndromes
0.707 0.293 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.707 0.293 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.707 0.293 0.000
Q00-Q07 Congenital malformations of the nervous system
0.706 0.294 0.000
F05.9 Delirium, unspecified
0.706 0.294 0.000
G70 Myasthenia gravis and other myoneural disorders
0.705 0.295 0.000
Q64 Other congenital malformations of urinary system
0.705 0.295 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.704 0.295 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.704 0.296 0.000
W50-W64 Exposure to animate mechanical forces
0.704 0.296 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.703 0.297 0.000
T14 Injury of unspecified body region
0.703 0.297 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.703 0.297 0.000
C81.9 Hodgkin's disease, unspecified
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.702 0.298 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.701 0.299 0.000
I82 Other venous embolism and thrombosis
0.701 0.299 0.000
I35.0 Aortic (valve) stenosis
0.700 0.300 0.000
H71 Cholesteatoma of middle ear
0.698 0.302 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.697 0.302 0.000
I88 Nonspecific lymphadenitis
0.695 0.304 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.695 0.305 0.000
Q61.9 Cystic kidney disease, unspecified
0.694 0.306 0.000
Q61.8 Other cystic kidney diseases
0.694 0.306 0.000
Q61.5 Medullary cystic kidney
0.694 0.306 0.000
Q61.4 Renal dysplasia
0.694 0.306 0.000
Q61.1 Polycystic kidney, infantile type
0.694 0.306 0.000
V20-V29 Motorcycle rider injured in transport accident
0.694 0.306 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.694 0.306 0.000
G37 Other demyelinating diseases of central nervous system
0.693 0.307 0.000
T78.3 Angioneurotic oedema
0.693 0.307 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.693 0.307 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.693 0.307 0.000
X60-X84 Intentional self-harm
0.693 0.307 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.691 0.309 0.000
G92 Toxic encephalopathy
0.690 0.310 0.000
C79 Secondary malignant neoplasm of other sites
0.689 0.311 0.000
C71 Malignant neoplasm of brain
0.687 0.313 0.000
D38.1 Trachea, bronchus and lung
0.687 0.313 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.686 0.314 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.686 0.314 0.000
W44 Foreign body entering into or through eye or natural orifice
0.685 0.315 0.000
G93.2 Benign intracranial hypertension
0.685 0.315 0.000
C91 Lymphoid leukaemia
0.685 0.315 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.684 0.316 0.000
D40.1 Testis
0.683 0.317 0.000
T68 Hypothermia
0.682 0.317 0.000
S02 Fracture of skull and facial bones
0.682 0.318 0.000
T90 Sequelae of injuries of head
0.679 0.321 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.679 0.321 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.678 0.322 0.000
I44.1 Atrioventricular block, second degree
0.678 0.322 0.000
G31.2 Degeneration of nervous system due to alcohol
0.678 0.322 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.678 0.322 0.000
G31.0 Circumscribed brain atrophy
0.678 0.322 0.000
H69 Other disorders of Eustachian tube
0.677 0.323 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.677 0.323 0.000
Q39 Congenital malformations of oesophagus
0.677 0.323 0.000
H74 Other disorders of middle ear and mastoid
0.677 0.323 0.000
G72.0 Drug-induced myopathy
0.676 0.323 0.000
T78.2 Anaphylactic shock, unspecified
0.676 0.324 0.000
I13 Hypertensive heart and renal disease
0.676 0.324 0.000
F99 Mental disorder, not otherwise specified
0.675 0.325 0.000
C67.3 Anterior wall of bladder
0.675 0.325 0.000
D47.2 Monoclonal gammopathy
0.674 0.326 0.000
T45.5 Anticoagulants
0.672 0.328 0.000
D46.7 Other myelodysplastic syndromes
0.671 0.329 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.671 0.329 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.671 0.329 0.000
D46.4 Refractory anaemia, unspecified
0.671 0.329 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.671 0.329 0.000
D46.1 Refractory anaemia with sideroblasts
0.671 0.329 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.671 0.329 0.000
Y40 Systemic antibiotics
0.671 0.329 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.671 0.329 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.670 0.330 0.000
I05-I09 Chronic rheumatic heart diseases
0.668 0.332 0.000
D43.0 Brain, supratentorial
0.666 0.334 0.000
G93.4 Encephalopathy, unspecified
0.664 0.336 0.000
T17 Foreign body in respiratory tract
0.663 0.337 0.000
C67.1 Dome of bladder
0.662 0.338 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.661 0.339 0.000
T75 Effects of other external causes
0.661 0.339 0.000
T74 Maltreatment syndromes
0.661 0.339 0.000
T73 Effects of other deprivation
0.661 0.339 0.000
T69 Other effects of reduced temperature
0.661 0.339 0.000
T67 Effects of heat and light
0.661 0.339 0.000
T71 Asphyxiation
0.661 0.339 0.000
T66 Unspecified effects of radiation
0.661 0.339 0.000
T23 Burn and corrosion of wrist and hand
0.660 0.340 0.000
F00 Dementia in Alzheimer's disease
0.660 0.340 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.660 0.340 0.000
F30-F39 Mood [affective] disorders
0.658 0.342 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.658 0.342 0.000
S70-S79 Injuries to the hip and thigh
0.658 0.342 0.000
T91 Sequelae of injuries of neck and trunk
0.658 0.342 0.000
G44 Other headache syndromes
0.657 0.343 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.657 0.343 0.000
H70 Mastoiditis and related conditions
0.657 0.343 0.000
H68 Eustachian salpingitis and obstruction
0.657 0.343 0.000
H67 Otitis media in diseases classified elsewhere
0.657 0.343 0.000
G95 Other diseases of spinal cord
0.656 0.344 0.000
I27 Other pulmonary heart diseases
0.655 0.345 0.000
F60 Specific personality disorders
0.655 0.345 0.000
T58 Toxic effect of carbon monoxide
0.654 0.346 0.000
T13 Other injuries of lower limb, level unspecified
0.654 0.346 0.000
I61 Intracerebral haemorrhage
0.654 0.346 0.000
I47 Paroxysmal tachycardia
0.653 0.347 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.653 0.347 0.000
T42.1 Iminostilbenes
0.653 0.347 0.000
Q53 Undescended testicle
0.652 0.348 0.000
F20 Schizophrenia
0.652 0.348 0.000
G03 Meningitis due to other and unspecified causes
0.652 0.348 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.652 0.348 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.652 0.348 0.000
T46.7 Peripheral vasodilators
0.652 0.348 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.652 0.348 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.652 0.348 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.652 0.348 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.652 0.348 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.652 0.348 0.000
G62 Other polyneuropathies
0.652 0.348 0.000
F29 Unspecified nonorganic psychosis
0.651 0.348 0.000
H60 Otitis externa
0.651 0.349 0.000
S20 Superficial injury of thorax
0.651 0.349 0.000
D47.4 Osteomyelofibrosis
0.650 0.350 0.000
G61 Inflammatory polyneuropathy
0.650 0.350 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.650 0.350 0.000
T78.4 Allergy, unspecified
0.648 0.352 0.000
I95.0 Idiopathic hypotension
0.648 0.352 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.648 0.352 0.000
Y35-Y36 Legal intervention and operations of war
0.648 0.352 0.000
Y10-Y34 Event of undetermined intent
0.648 0.352 0.000
Y00-Y09 Assault
0.648 0.352 0.000
X85-X99 Assault
0.648 0.352 0.000
X30-X39 Exposure to forces of nature
0.648 0.352 0.000
X00-X09 Exposure to smoke, fire and flames
0.648 0.352 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.648 0.352 0.000
W75-W84 Other accidental threats to breathing
0.648 0.352 0.000
W65-W74 Accidental drowning and submersion
0.648 0.352 0.000
V98-V99 Other and unspecified transport accidents
0.648 0.352 0.000
V95-V97 Air and space transport accidents
0.648 0.352 0.000
V90-V94 Water transport accidents
0.648 0.352 0.000
V70-V79 Bus occupant injured in transport accident
0.648 0.352 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.648 0.352 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.648 0.352 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.648 0.352 0.000
V01-V09 Pedestrian injured in transport accident
0.648 0.352 0.000
I87 Other disorders of veins
0.647 0.352 0.000
W44.0 Home
0.647 0.353 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.646 0.354 0.000
T20 Burn and corrosion of head and neck
0.646 0.354 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.645 0.355 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.645 0.355 0.000
G45.0 Vertebro-basilar artery syndrome
0.645 0.355 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.645 0.355 0.000
F70-F79 Mental retardation
0.645 0.355 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.645 0.355 0.000
G97.8 Other postprocedural disorders of nervous system
0.644 0.356 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.644 0.356 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.644 0.356 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.643 0.357 0.000
C15-C26 Malignant neoplasms of digestive organs
0.642 0.358 0.000
S01 Open wound of head
0.641 0.359 0.000
I12.9 Hypertensive renal disease without renal failure
0.640 0.360 0.000
G30.9 Alzheimer's disease, unspecified
0.640 0.360 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.640 0.360 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.640 0.360 0.000
C09 Malignant neoplasm of tonsil
0.640 0.360 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.639 0.361 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.638 0.362 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.637 0.362 0.000
T25 Burn and corrosion of ankle and foot
0.637 0.363 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.637 0.363 0.000
C92 Myeloid leukaemia
0.636 0.364 0.000
H72.2 Other marginal perforations of tympanic membrane
0.636 0.364 0.000
H72.1 Attic perforation of tympanic membrane
0.636 0.364 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.635 0.365 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.635 0.365 0.000
C77.3 Axillary and upper limb lymph nodes
0.634 0.366 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.633 0.367 0.000
I38 Endocarditis, valve unspecified
0.633 0.367 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.633 0.367 0.000
C74 Malignant neoplasm of adrenal gland
0.633 0.367 0.000
I12.0 Hypertensive renal disease with renal failure
0.633 0.367 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.632 0.368 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.632 0.368 0.000
G00 Bacterial meningitis, not elsewhere classified
0.632 0.368 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.632 0.368 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.632 0.368 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.632 0.368 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.631 0.369 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.631 0.369 0.000
T47.7 Emetics
0.631 0.369 0.000
T47.6 Antidiarrhoeal drugs
0.631 0.369 0.000
T47.5 Digestants
0.631 0.369 0.000
T47.4 Other laxatives
0.631 0.369 0.000
T47.3 Saline and osmotic laxatives
0.631 0.369 0.000
T47.2 Stimulant laxatives
0.631 0.369 0.000
T47.0 Histamine H(2)-receptor antagonists
0.631 0.369 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.631 0.369 0.000
C95 Leukaemia of unspecified cell type
0.631 0.369 0.000
C94 Other leukaemias of specified cell type
0.631 0.369 0.000
C93 Monocytic leukaemia
0.631 0.369 0.000
C86 Other specified types of T/NK-cell lymphoma
0.631 0.369 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.631 0.369 0.000
T11 Other injuries of upper limb, level unspecified
0.630 0.370 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.630 0.370 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.629 0.371 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.628 0.372 0.000
D40.9 Male genital organ, unspecified
0.627 0.373 0.000
D40.7 Other male genital organs
0.627 0.373 0.000
X23 Contact with hornets, wasps and bees
0.627 0.373 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.626 0.374 0.000
G91.9 Hydrocephalus, unspecified
0.626 0.374 0.000
Q44.6 Cystic disease of liver
0.625 0.375 0.000
G46.4 Cerebellar stroke syndrome
0.625 0.375 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.624 0.376 0.000
T45.0 Antiallergic and antiemetic drugs
0.623 0.377 0.000
G91.2 Normal-pressure hydrocephalus
0.622 0.378 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.622 0.378 0.000
S91 Open wound of ankle and foot
0.621 0.378 0.000
H81 Disorders of vestibular function
0.621 0.379 0.000
D47.1 Chronic myeloproliferative disease
0.621 0.379 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.621 0.379 0.000
G60 Hereditary and idiopathic neuropathy
0.620 0.380 0.000
Q85 Phakomatoses, not elsewhere classified
0.620 0.380 0.000
I35.9 Aortic valve disorder, unspecified
0.619 0.381 0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot
0.619 0.381 0.000
C10 Malignant neoplasm of oropharynx
0.619 0.381 0.000
I15.1 Hypertension secondary to other renal disorders
0.619 0.381 0.000
Q60.2 Renal agenesis, unspecified
0.617 0.383 0.000
T19 Foreign body in genito-urinary tract
0.617 0.383 0.000
T15 Foreign body on external eye
0.617 0.383 0.000
T16 Foreign body in ear
0.617 0.383 0.000
C69 Malignant neoplasm of eye and adnexa
0.616 0.384 0.000
T36.0 Penicillins
0.615 0.385 0.000
G93.9 Disorder of brain, unspecified
0.615 0.385 0.000
Y52 Agents primarily affecting the cardiovascular system
0.614 0.386 0.000
H73 Other disorders of tympanic membrane
0.613 0.387 0.000
T18.1 Foreign body in oesophagus
0.613 0.387 0.000
I95.8 Other hypotension
0.613 0.387 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.613 0.387 0.000
Q45 Other congenital malformations of digestive system
0.612 0.388 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.612 0.388 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.612 0.388 0.000
Q40 Other congenital malformations of upper alimentary tract
0.612 0.388 0.000
C01 Malignant neoplasm of base of tongue
0.612 0.388 0.000
G93.7 Reye's syndrome
0.612 0.388 0.000
G93.5 Compression of brain
0.612 0.388 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.612 0.388 0.000
I69 Sequelae of cerebrovascular disease
0.612 0.388 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.611 0.388 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.609 0.391 0.000
T09 Other injuries of spine and trunk, level unspecified
0.608 0.391 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.608 0.391 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.608 0.391 0.000
T12 Fracture of lower limb, level unspecified
0.608 0.391 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.608 0.391 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.608 0.391 0.000
T10 Fracture of upper limb, level unspecified
0.608 0.391 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.608 0.391 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.608 0.391 0.000
T08 Fracture of spine, level unspecified
0.608 0.391 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.608 0.391 0.000
S05 Injury of eye and orbit
0.609 0.391 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.608 0.392 0.000
T95 Sequelae of burns, corrosions and frostbite
0.608 0.392 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.608 0.392 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.608 0.392 0.000
Y40.9 Systemic antibiotic, unspecified
0.608 0.392 0.000
T21.2 Burn of second degree of trunk
0.608 0.392 0.000
T78.9 Adverse effect, unspecified
0.607 0.392 0.000
T78.8 Other adverse effects, not elsewhere classified
0.607 0.392 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.606 0.394 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.606 0.394 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.606 0.394 0.000
T42.3 Barbiturates
0.606 0.394 0.000
T42.2 Succinimides and oxazolidinediones
0.606 0.394 0.000
T42.0 Hydantoin derivatives
0.606 0.394 0.000
I67 Other cerebrovascular diseases
0.606 0.394 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.606 0.394 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.606 0.394 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.606 0.394 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.606 0.394 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.605 0.395 0.000
D41.4 Bladder
0.604 0.396 0.000
G47.3 Sleep apnoea
0.604 0.396 0.000
I44.3 Other and unspecified atrioventricular block
0.604 0.396 0.000
G94.1 Hydrocephalus in neoplastic disease
0.604 0.396 0.000
S27 Injury of other and unspecified intrathoracic organs
0.603 0.397 0.000
G83 Other paralytic syndromes
0.603 0.397 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.603 0.397 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.602 0.398 0.000
C53 Malignant neoplasm of cervix uteri
0.602 0.398 0.000
D48.5 Skin
0.602 0.398 0.000
F23 Acute and transient psychotic disorders
0.602 0.398 0.000
C81.1 Nodular sclerosis
0.601 0.398 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.601 0.398 0.000
Q55 Other congenital malformations of male genital organs
0.601 0.398 0.000
Q54 Hypospadias
0.601 0.398 0.000
Q52 Other congenital malformations of female genitalia
0.601 0.398 0.000
H65 Nonsuppurative otitis media
0.600 0.400 0.000
T14.0 Superficial injury of unspecified body region
0.599 0.401 0.000
V40-V49 Car occupant injured in transport accident
0.598 0.401 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.597 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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