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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77119043
log Bayes Factor = 15.2787
Chromosome 8   position 48,313,295  (GRCh37) Explore rs77119043 on Ensembl!
Variant rs77119043 is part of Cluster X0110

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.985 0.015 0.000
J09-J18 Influenza and pneumonia
0.983 0.017 0.000
E10 Insulin-dependent diabetes mellitus
0.973 0.027 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.972 0.028 0.000
Chapter XI Diseases of the digestive system
0.968 0.032 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.962 0.038 0.000
E11 Non-insulin-dependent diabetes mellitus
0.959 0.041 0.000
K70-K77 Diseases of liver
0.956 0.044 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.954 0.046 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.953 0.047 0.000
S40-S49 Injuries to the shoulder and upper arm
0.950 0.050 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.950 0.050 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.946 0.054 0.000
M20-M25 Other joint disorders
0.946 0.054 0.000
J47 Bronchiectasis
0.943 0.057 0.000
S00-S09 Injuries to the head
0.941 0.059 0.000
I34 Nonrheumatic mitral valve disorders
0.940 0.060 0.000
E10.9 Without complications
0.939 0.061 0.000
I45 Other conduction disorders
0.937 0.063 0.000
J18 Pneumonia, organism unspecified
0.936 0.064 0.000
S80-S89 Injuries to the knee and lower leg
0.935 0.065 0.000
I60-I69 Cerebrovascular diseases
0.929 0.071 0.000
K90-K93 Other diseases of the digestive system
0.928 0.072 0.000
E16 Other disorders of pancreatic internal secretion
0.920 0.080 0.000
Chapter XX External causes of morbidity and mortality
0.916 0.084 0.000
S70-S79 Injuries to the hip and thigh
0.915 0.085 0.000
Chapter VI Diseases of the nervous system
0.915 0.085 0.000
M23 Internal derangement of knee
0.906 0.094 0.000
J95-J99 Other diseases of the respiratory system
0.901 0.099 0.000
I42 Cardiomyopathy
0.897 0.103 0.000
E16.2 Hypoglycaemia, unspecified
0.896 0.104 0.000
M35 Other systemic involvement of connective tissue
0.895 0.105 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.890 0.110 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.885 0.115 0.000
I05-I09 Chronic rheumatic heart diseases
0.883 0.117 0.000
I45.1 Other and unspecified right bundle-branch block
0.882 0.118 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.882 0.118 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.882 0.118 0.000
E70-E90 Metabolic disorders
0.881 0.119 0.000
J43 Emphysema
0.875 0.125 0.000
J18.9 Pneumonia, unspecified
0.875 0.125 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.872 0.128 0.000
J00-J06 Acute upper respiratory infections
0.870 0.130 0.000
K74 Fibrosis and cirrhosis of liver
0.869 0.131 0.000
J40 Bronchitis, not specified as acute or chronic
0.869 0.131 0.000
E11.9 Without complications
0.867 0.133 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.867 0.133 0.000
K92 Other diseases of digestive system
0.867 0.133 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.861 0.139 0.000
I49 Other cardiac arrhythmias
0.861 0.139 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.855 0.145 0.000
R73 Elevated blood glucose level
0.853 0.147 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.853 0.147 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.850 0.150 0.000
J46 Status asthmaticus
0.847 0.153 0.000
K92.1 Melaena
0.847 0.153 0.000
I51 Complications and ill-defined descriptions of heart disease
0.846 0.154 0.000
K75 Other inflammatory liver diseases
0.843 0.157 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.842 0.158 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.840 0.160 0.000
Chapter I Certain infectious and parasitic diseases
0.835 0.165 0.000
K72 Hepatic failure, not elsewhere classified
0.835 0.165 0.000
E10.1 With ketoacidosis
0.834 0.166 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.833 0.167 0.000
E11.3 With ophthalmic complications
0.830 0.170 0.000
J98 Other respiratory disorders
0.829 0.171 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.829 0.171 0.000
S42 Fracture of shoulder and upper arm
0.828 0.172 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.828 0.172 0.000
S01 Open wound of head
0.828 0.172 0.000
I20-I25 Ischaemic heart diseases
0.825 0.175 0.000
I50 Heart failure
0.823 0.177 0.000
I10-I15 Hypertensive diseases
0.821 0.179 0.000
M80-M85 Disorders of bone density and structure
0.818 0.182 0.000
I63 Cerebral infarction
0.817 0.183 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.814 0.186 0.000
I33 Acute and subacute endocarditis
0.814 0.186 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.813 0.186 0.000
D80-D89 Certain disorders involving the immune mechanism
0.813 0.187 0.000
R11 Nausea and vomiting
0.813 0.187 0.000
S80 Superficial injury of lower leg
0.812 0.188 0.000
M35.3 Polymyalgia rheumatica
0.809 0.191 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.808 0.192 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.807 0.193 0.000
I46 Cardiac arrest
0.806 0.194 0.000
I27 Other pulmonary heart diseases
0.805 0.195 0.000
I34.1 Mitral (valve) prolapse
0.805 0.195 0.000
S72 Fracture of femur
0.803 0.196 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.802 0.198 0.000
I47 Paroxysmal tachycardia
0.801 0.199 0.000
E20-E35 Disorders of other endocrine glands
0.801 0.199 0.000
D60-D64 Aplastic and other anaemias
0.799 0.201 0.000
I34.0 Mitral (valve) insufficiency
0.795 0.205 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.794 0.206 0.000
S81 Open wound of lower leg
0.793 0.207 0.000
M24 Other specific joint derangements
0.792 0.208 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.789 0.211 0.000
J18.0 Bronchopneumonia, unspecified
0.788 0.212 0.000
D69 Purpura and other haemorrhagic conditions
0.788 0.212 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.787 0.213 0.000
J43.9 Emphysema, unspecified
0.786 0.214 0.000
M35.0 Sicca syndrome [Sjogren]
0.786 0.214 0.000
J60-J70 Lung diseases due to external agents
0.785 0.215 0.000
R17 Unspecified jaundice
0.784 0.216 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.782 0.218 0.000
G40-G47 Episodic and paroxysmal disorders
0.781 0.218 0.000
E11.4 With neurological complications
0.780 0.220 0.000
I05 Rheumatic mitral valve diseases
0.780 0.220 0.000
S40 Superficial injury of shoulder and upper arm
0.779 0.221 0.000
Chapter XXII Codes for special purposes
0.778 0.222 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.778 0.222 0.000
I12 Hypertensive renal disease
0.778 0.222 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.776 0.224 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.775 0.225 0.000
M91-M94 Chondropathies
0.770 0.229 0.000
I42.9 Cardiomyopathy, unspecified
0.769 0.231 0.000
S20-S29 Injuries to the thorax
0.768 0.232 0.000
R47-R49 Symptoms and signs involving speech and voice
0.768 0.232 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.768 0.232 0.000
I38 Endocarditis, valve unspecified
0.763 0.237 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.762 0.238 0.000
K76 Other diseases of liver
0.762 0.238 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.762 0.238 0.000
S02 Fracture of skull and facial bones
0.761 0.238 0.000
K74.6 Other and unspecified cirrhosis of liver
0.759 0.241 0.000
I67 Other cerebrovascular diseases
0.758 0.242 0.000
S82 Fracture of lower leg, including ankle
0.757 0.243 0.000
J98.4 Other disorders of lung
0.756 0.244 0.000
M05-M14 Inflammatory polyarthropathies
0.756 0.244 0.000
S05 Injury of eye and orbit
0.756 0.244 0.000
G90-G99 Other disorders of the nervous system
0.756 0.244 0.000
I25 Chronic ischaemic heart disease
0.756 0.244 0.000
E10.4 With neurological complications
0.751 0.249 0.000
I31 Other diseases of pericardium
0.750 0.250 0.000
S00 Superficial injury of head
0.749 0.251 0.000
R18 Ascites
0.749 0.251 0.000
K72.9 Hepatic failure, unspecified
0.748 0.252 0.000
J30-J39 Other diseases of upper respiratory tract
0.746 0.254 0.000
J00 Acute nasopharyngitis [common cold]
0.746 0.254 0.000
W00-W19 Falls
0.746 0.254 0.000
Chapter VIII Diseases of the ear and mastoid process
0.745 0.255 0.000
S71 Open wound of hip and thigh
0.744 0.255 0.000
E40-E46 Malnutrition
0.744 0.256 0.000
R74 Abnormal serum enzyme levels
0.743 0.256 0.000
I12.0 Hypertensive renal disease with renal failure
0.740 0.260 0.000
R42 Dizziness and giddiness
0.740 0.260 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.739 0.261 0.000
G51 Facial nerve disorders
0.738 0.262 0.000
R79 Other abnormal findings of blood chemistry
0.738 0.262 0.000
E11.2 With renal complications
0.737 0.263 0.000
J90-J94 Other diseases of pleura
0.737 0.263 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.737 0.263 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.737 0.263 0.000
K70 Alcoholic liver disease
0.735 0.265 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.735 0.265 0.000
E88 Other metabolic disorders
0.735 0.265 0.000
R73.9 Hyperglycaemia, unspecified
0.733 0.267 0.000
Chapter VII Diseases of the eye and adnexa
0.733 0.267 0.000
E14 Unspecified diabetes mellitus
0.733 0.267 0.000
K74.3 Primary biliary cirrhosis
0.732 0.268 0.000
S42.2 Fracture of upper end of humerus
0.728 0.272 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.725 0.275 0.000
I27.0 Primary pulmonary hypertension
0.725 0.275 0.000
M22 Disorders of patella
0.722 0.278 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.721 0.278 0.000
K08 Other disorders of teeth and supporting structures
0.721 0.279 0.000
M81 Osteoporosis without pathological fracture
0.721 0.279 0.000
G40 Epilepsy
0.721 0.279 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.720 0.279 0.000
I45.6 Preexcitation syndrome
0.720 0.280 0.000
I51.7 Cardiomegaly
0.720 0.280 0.000
I65.2 Occlusion and stenosis of carotid artery
0.720 0.280 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.719 0.281 0.000
M50-M54 Other dorsopathies
0.718 0.282 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
I44 Atrioventricular and left bundle-branch block
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
S80.9 Superficial injury of lower leg, unspecified
0.716 0.284 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.716 0.284 0.000
T81 Complications of procedures, not elsewhere classified
0.716 0.284 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.715 0.285 0.000
K04 Diseases of pulp and periapical tissues
0.715 0.285 0.000
Y44 Agents primarily affecting blood constituents
0.715 0.285 0.000
R73.0 Abnormal glucose tolerance test
0.714 0.286 0.000
Y43 Primarily systemic agents
0.714 0.286 0.000
E13 Other specified diabetes mellitus
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.286 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.713 0.287 0.000
I08 Multiple valve diseases
0.712 0.288 0.000
J03 Acute tonsillitis
0.712 0.288 0.000
E83 Disorders of mineral metabolism
0.711 0.289 0.000
D86 Sarcoidosis
0.710 0.290 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.710 0.290 0.000
K75.4 Autoimmune hepatitis
0.709 0.291 0.000
K65-K67 Diseases of peritoneum
0.709 0.291 0.000
E86 Volume depletion
0.708 0.292 0.000
I51.9 Heart disease, unspecified
0.707 0.293 0.000
E50-E64 Other nutritional deficiencies
0.707 0.293 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.706 0.294 0.000
K50-K52 Noninfective enteritis and colitis
0.705 0.295 0.000
J17 Pneumonia in diseases classified elsewhere
0.705 0.295 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.705 0.295 0.000
J12 Viral pneumonia, not elsewhere classified
0.705 0.295 0.000
J11 Influenza, virus not identified
0.705 0.295 0.000
J10 Influenza due to identified influenza virus
0.705 0.295 0.000
J14 Pneumonia due to Haemophilus influenzae
0.705 0.295 0.000
J09 Influenza due to certain identified influenza virus
0.705 0.295 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.704 0.296 0.000
T66-T78 Other and unspecified effects of external causes
0.702 0.298 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.702 0.298 0.000
R44.1 Visual hallucinations
0.702 0.298 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.700 0.300 0.000
K75.8 Other specified inflammatory liver diseases
0.698 0.302 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.697 0.302 0.000
E10.8 With unspecified complications
0.697 0.302 0.000
E10.7 With multiple complications
0.697 0.302 0.000
E10.6 With other specified complications
0.697 0.302 0.000
E10.5 With peripheral circulatory complications
0.697 0.302 0.000
E10.2 With renal complications
0.697 0.302 0.000
E10.0 With coma
0.697 0.302 0.000
V10-V19 Pedal cyclist injured in transport accident
0.697 0.303 0.000
I49.5 Sick sinus syndrome
0.696 0.304 0.000
S89 Other and unspecified injuries of lower leg
0.693 0.307 0.000
M65-M68 Disorders of synovium and tendon
0.693 0.307 0.000
J42 Unspecified chronic bronchitis
0.693 0.307 0.000
S90-S99 Injuries to the ankle and foot
0.692 0.308 0.000
I42.0 Dilated cardiomyopathy
0.691 0.309 0.000
S79 Other and unspecified injuries of hip and thigh
0.691 0.309 0.000
M60-M63 Disorders of muscles
0.690 0.310 0.000
M00-M03 Infectious arthropathies
0.690 0.310 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.690 0.310 0.000
G51.0 Bell's palsy
0.688 0.312 0.000
D64 Other anaemias
0.688 0.312 0.000
E11.8 With unspecified complications
0.688 0.312 0.000
E11.7 With multiple complications
0.688 0.312 0.000
E11.6 With other specified complications
0.688 0.312 0.000
E11.1 With ketoacidosis
0.688 0.312 0.000
E11.0 With coma
0.688 0.312 0.000
I05.0 Mitral stenosis
0.686 0.314 0.000
K77 Liver disorders in diseases classified elsewhere
0.685 0.315 0.000
K73 Chronic hepatitis, not elsewhere classified
0.685 0.315 0.000
K71 Toxic liver disease
0.685 0.315 0.000
D55-D59 Haemolytic anaemias
0.684 0.316 0.000
E15 Nondiabetic hypoglycaemic coma
0.683 0.317 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.683 0.317 0.000
D69.6 Thrombocytopenia, unspecified
0.682 0.318 0.000
B25-B34 Other viral diseases
0.682 0.318 0.000
I67.8 Other specified cerebrovascular diseases
0.682 0.318 0.000
I49.9 Cardiac arrhythmia, unspecified
0.682 0.318 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.681 0.318 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.681 0.319 0.000
S48 Traumatic amputation of shoulder and upper arm
0.681 0.319 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.681 0.319 0.000
S44 Injury of nerves at shoulder and upper arm level
0.681 0.319 0.000
S41 Open wound of shoulder and upper arm
0.681 0.319 0.000
S47 Crushing injury of shoulder and upper arm
0.681 0.319 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.681 0.319 0.000
R77 Other abnormalities of plasma proteins
0.681 0.319 0.000
R76 Other abnormal immunological findings in serum
0.681 0.319 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.681 0.319 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.681 0.319 0.000
R71 Abnormality of red blood cells
0.681 0.319 0.000
I33.0 Acute and subacute infective endocarditis
0.680 0.320 0.000
K76.6 Portal hypertension
0.680 0.320 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.678 0.322 0.000
M34 Systemic sclerosis
0.678 0.322 0.000
M33 Dermatopolymyositis
0.678 0.322 0.000
M32 Systemic lupus erythematosus
0.678 0.322 0.000
M30 Polyarteritis nodosa and related conditions
0.678 0.322 0.000
M21 Other acquired deformities of limbs
0.678 0.322 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.677 0.323 0.000
R40 Somnolence, stupor and coma
0.676 0.324 0.000
I50.1 Left ventricular failure
0.676 0.324 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.676 0.324 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.675 0.325 0.000
S08 Traumatic amputation of part of head
0.675 0.325 0.000
S07 Crushing injury of head
0.675 0.325 0.000
S04 Injury of cranial nerves
0.675 0.325 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.675 0.325 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.674 0.326 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.674 0.326 0.000
M86-M90 Other osteopathies
0.674 0.326 0.000
I63.8 Other cerebral infarction
0.674 0.326 0.000
S72.1 Pertrochanteric fracture
0.673 0.327 0.000
I45.9 Conduction disorder, unspecified
0.672 0.328 0.000
I45.8 Other specified conduction disorders
0.672 0.328 0.000
I45.5 Other specified heart block
0.672 0.328 0.000
I45.4 Nonspecific intraventricular block
0.672 0.328 0.000
I45.3 Trifascicular block
0.672 0.328 0.000
I45.2 Bifascicular block
0.672 0.328 0.000
I45.0 Right fascicular block
0.672 0.328 0.000
S01.1 Open wound of eyelid and periocular area
0.671 0.329 0.000
J18.8 Other pneumonia, organism unspecified
0.671 0.329 0.000
J18.2 Hypostatic pneumonia, unspecified
0.671 0.329 0.000
J18.1 Lobar pneumonia, unspecified
0.671 0.329 0.000
S88 Traumatic amputation of lower leg
0.670 0.329 0.000
S87 Crushing injury of lower leg
0.670 0.329 0.000
S86 Injury of muscle and tendon at lower leg level
0.670 0.329 0.000
S85 Injury of blood vessels at lower leg level
0.670 0.329 0.000
S84 Injury of nerves at lower leg level
0.670 0.329 0.000
S70 Superficial injury of hip and thigh
0.670 0.330 0.000
K10 Other diseases of jaws
0.670 0.330 0.000
M31 Other necrotising vasculopathies
0.669 0.331 0.000
I49.8 Other specified cardiac arrhythmias
0.669 0.331 0.000
S06 Intracranial injury
0.667 0.332 0.000
K91.3 Postoperative intestinal obstruction
0.667 0.333 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.666 0.334 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.666 0.334 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.665 0.335 0.000
M24.1 Other articular cartilage disorders
0.664 0.336 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.664 0.336 0.000
S72.0 Fracture of neck of femur
0.663 0.337 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.662 0.337 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.662 0.338 0.000
H10-H13 Disorders of conjunctiva
0.662 0.338 0.000
E11.5 With peripheral circulatory complications
0.661 0.339 0.000
I50.9 Heart failure, unspecified
0.661 0.339 0.000
S00.9 Superficial injury of head, part unspecified
0.660 0.340 0.000
Y57 Other and unspecified drugs and medicaments
0.660 0.340 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.660 0.340 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.659 0.340 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.659 0.340 0.000
E16.4 Abnormal secretion of gastrin
0.659 0.340 0.000
E16.3 Increased secretion of glucagon
0.659 0.340 0.000
E16.1 Other hypoglycaemia
0.659 0.340 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.659 0.340 0.000
S09 Other and unspecified injuries of head
0.659 0.340 0.000
R50-R69 General symptoms and signs
0.659 0.341 0.000
I46.0 Cardiac arrest with successful resuscitation
0.659 0.341 0.000
K11 Diseases of salivary glands
0.658 0.342 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.658 0.342 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.657 0.343 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.657 0.343 0.000
I69 Sequelae of cerebrovascular disease
0.657 0.343 0.000
G70-G73 Diseases of myoneural junction and muscle
0.657 0.343 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.657 0.343 0.000
M23.4 Loose body in knee
0.657 0.343 0.000
S42.20 Fracture of upper end of humerus (closed)
0.657 0.343 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.657 0.343 0.000
Y35-Y36 Legal intervention and operations of war
0.657 0.343 0.000
Y10-Y34 Event of undetermined intent
0.657 0.343 0.000
Y00-Y09 Assault
0.657 0.343 0.000
X85-X99 Assault
0.657 0.343 0.000
X60-X84 Intentional self-harm
0.657 0.343 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.657 0.343 0.000
X50-X57 Overexertion, travel and privation
0.657 0.343 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.657 0.343 0.000
X30-X39 Exposure to forces of nature
0.657 0.343 0.000
X20-X29 Contact with venomous animals and plants
0.657 0.343 0.000
X10-X19 Contact with heat and hot substances
0.657 0.343 0.000
X00-X09 Exposure to smoke, fire and flames
0.657 0.343 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.657 0.343 0.000
W75-W84 Other accidental threats to breathing
0.657 0.343 0.000
W65-W74 Accidental drowning and submersion
0.657 0.343 0.000
W50-W64 Exposure to animate mechanical forces
0.657 0.343 0.000
V98-V99 Other and unspecified transport accidents
0.657 0.343 0.000
V95-V97 Air and space transport accidents
0.657 0.343 0.000
V90-V94 Water transport accidents
0.657 0.343 0.000
V80-V89 Other land transport accidents
0.657 0.343 0.000
V70-V79 Bus occupant injured in transport accident
0.657 0.343 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.657 0.343 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.657 0.343 0.000
V40-V49 Car occupant injured in transport accident
0.657 0.343 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.657 0.343 0.000
V20-V29 Motorcycle rider injured in transport accident
0.657 0.343 0.000
V01-V09 Pedestrian injured in transport accident
0.657 0.343 0.000
S78 Traumatic amputation of hip and thigh
0.656 0.344 0.000
S77 Crushing injury of hip and thigh
0.656 0.344 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.656 0.344 0.000
S75 Injury of blood vessels at hip and thigh level
0.656 0.344 0.000
S74 Injury of nerves at hip and thigh level
0.656 0.344 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.656 0.344 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.656 0.344 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.656 0.344 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.656 0.344 0.000
A30-A49 Other bacterial diseases
0.655 0.345 0.000
D75 Other diseases of blood and blood-forming organs
0.655 0.345 0.000
H90-H95 Other disorders of ear
0.653 0.347 0.000
S42.1 Fracture of scapula
0.652 0.348 0.000
M81.9 Osteoporosis, unspecified
0.652 0.348 0.000
A00-A09 Intestinal infectious diseases
0.651 0.349 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.651 0.349 0.000
I60 Subarachnoid haemorrhage
0.650 0.349 0.000
E10.3 With ophthalmic complications
0.650 0.350 0.000
S01.8 Open wound of other parts of head
0.650 0.350 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.650 0.350 0.000
M23.9 Internal derangement of knee, unspecified
0.649 0.351 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.649 0.351 0.000
M23.5 Chronic instability of knee
0.649 0.351 0.000
M23.1 Discoid meniscus (congenital)
0.649 0.351 0.000
M23.0 Cystic meniscus
0.649 0.351 0.000
J98.1 Pulmonary collapse
0.649 0.351 0.000
S01.5 Open wound of lip and oral cavity
0.649 0.351 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.648 0.352 0.000
I62 Other nontraumatic intracranial haemorrhage
0.647 0.353 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.646 0.354 0.000
J96 Respiratory failure, not elsewhere classified
0.646 0.354 0.000
R50 Fever of unknown origin
0.646 0.354 0.000
R80 Isolated proteinuria
0.646 0.354 0.000
R82 Other abnormal findings in urine
0.645 0.355 0.000
I42.8 Other cardiomyopathies
0.643 0.357 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.643 0.357 0.000
I42.6 Alcoholic cardiomyopathy
0.643 0.357 0.000
I42.5 Other restrictive cardiomyopathy
0.643 0.357 0.000
I42.4 Endocardial fibroelastosis
0.643 0.357 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.643 0.357 0.000
I42.2 Other hypertrophic cardiomyopathy
0.643 0.357 0.000
I35 Nonrheumatic aortic valve disorders
0.642 0.358 0.000
B95-B98 Bacterial, viral and other infectious agents
0.642 0.358 0.000
G93 Other disorders of brain
0.642 0.358 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.642 0.358 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.641 0.358 0.000
M35.8 Other specified systemic involvement of connective tissue
0.641 0.358 0.000
M35.7 Hypermobility syndrome
0.641 0.358 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.641 0.358 0.000
M35.5 Multifocal fibrosclerosis
0.641 0.358 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.641 0.358 0.000
M35.2 Behcet's disease
0.641 0.358 0.000
M35.1 Other overlap syndromes
0.641 0.358 0.000
K35-K38 Diseases of appendix
0.640 0.359 0.000
S81.0 Open wound of knee
0.640 0.360 0.000
D68 Other coagulation defects
0.640 0.360 0.000
J15.2 Pneumonia due to staphylococcus
0.640 0.360 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.639 0.361 0.000
R50.9 Fever, unspecified
0.639 0.361 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.638 0.361 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.638 0.362 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.638 0.362 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.637 0.363 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.637 0.363 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.636 0.364 0.000
I49.0 Ventricular fibrillation and flutter
0.636 0.364 0.000
G30-G32 Other degenerative diseases of the nervous system
0.635 0.365 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.635 0.365 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.634 0.366 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.634 0.366 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.634 0.366 0.000
S60-S69 Injuries to the wrist and hand
0.633 0.367 0.000
I09 Other rheumatic heart diseases
0.633 0.367 0.000
I06 Rheumatic aortic valve diseases
0.633 0.367 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.633 0.367 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.633 0.367 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.633 0.367 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.633 0.367 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.633 0.367 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.633 0.367 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.633 0.367 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.633 0.367 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.633 0.367 0.000
T36 Poisoning by systemic antibiotics
0.633 0.367 0.000
S01.0 Open wound of scalp
0.632 0.367 0.000
R47 Speech disturbances, not elsewhere classified
0.632 0.367 0.000
R46 Symptoms and signs involving appearance and behaviour
0.632 0.368 0.000
R43 Disturbances of smell and taste
0.632 0.368 0.000
E85 Amyloidosis
0.632 0.368 0.000
E84 Cystic fibrosis
0.632 0.368 0.000
E79 Disorders of purine and pyrimidine metabolism
0.632 0.368 0.000
E77 Disorders of glycoprotein metabolism
0.632 0.368 0.000
E76 Disorders of glycosaminoglycan metabolism
0.632 0.368 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.632 0.368 0.000
E74 Other disorders of carbohydrate metabolism
0.632 0.368 0.000
E73 Lactose intolerance
0.632 0.368 0.000
E72 Other disorders of amino-acid metabolism
0.632 0.368 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.632 0.368 0.000
E70 Disorders of aromatic amino-acid metabolism
0.632 0.368 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.632 0.368 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.632 0.368 0.000
S81.9 Open wound of lower leg, part unspecified
0.631 0.369 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.630 0.370 0.000
I27.2 Other secondary pulmonary hypertension
0.630 0.370 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.629 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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