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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77271258
log Bayes Factor = 17.9401
Chromosome 1   position 218,056,637  (GRCh37) Explore rs77271258 on Ensembl!
Variant rs77271258 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T81 Complications of procedures, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.997 0.003 0.000
Chapter II Neoplasms
0.996 0.004 0.000
N30-N39 Other diseases of urinary system
0.992 0.008 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.991 0.009 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.989 0.011 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.986 0.014 0.000
Chapter XXI Factors influencing health status and contact with health services
0.985 0.015 0.000
Chapter I Certain infectious and parasitic diseases
0.985 0.015 0.000
Chapter VII Diseases of the eye and adnexa
0.985 0.015 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.985 0.015 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.979 0.021 0.000
N10-N16 Renal tubulo-interstitial diseases
0.973 0.027 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.971 0.029 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.970 0.030 0.000
N76 Other inflammation of vagina and vulva
0.968 0.032 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.967 0.033 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.964 0.036 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.964 0.036 0.000
C50-C50 Malignant neoplasm of breast
0.964 0.036 0.000
N89 Other noninflammatory disorders of vagina
0.959 0.041 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.959 0.041 0.000
B95-B98 Bacterial, viral and other infectious agents
0.958 0.042 0.000
Z51 Other medical care
0.957 0.043 0.000
Chapter VI Diseases of the nervous system
0.955 0.045 0.000
N32 Other disorders of bladder
0.953 0.047 0.000
Y83.6 Removal of other organ (partial) (total)
0.951 0.049 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.950 0.050 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.945 0.055 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.944 0.056 0.000
Z51.2 Other chemotherapy
0.943 0.057 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.942 0.058 0.000
C50 Malignant neoplasm of breast
0.941 0.059 0.000
Z93 Artificial opening status
0.940 0.060 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.939 0.061 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.938 0.062 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.936 0.064 0.000
N32.0 Bladder-neck obstruction
0.931 0.069 0.000
Y86 Sequelae of other accidents
0.930 0.070 0.000
N13 Obstructive and reflux uropathy
0.929 0.071 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.919 0.081 0.000
M20-M25 Other joint disorders
0.919 0.081 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.917 0.083 0.000
Q60-Q64 Congenital malformations of the urinary system
0.916 0.084 0.000
N76.4 Abscess of vulva
0.914 0.086 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.912 0.088 0.000
Z42 Follow-up care involving plastic surgery
0.909 0.091 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.909 0.091 0.000
M25 Other joint disorders, not elsewhere classified
0.908 0.092 0.000
N73 Other female pelvic inflammatory diseases
0.904 0.096 0.000
D10-D36 Benign neoplasms
0.893 0.107 0.000
N30 Cystitis
0.892 0.108 0.000
H25-H28 Disorders of lens
0.892 0.108 0.000
Z98 Other postsurgical states
0.889 0.111 0.000
S40-S49 Injuries to the shoulder and upper arm
0.883 0.117 0.000
Q61 Cystic kidney disease
0.881 0.119 0.000
C50.5 Lower-outer quadrant of breast
0.876 0.124 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.874 0.126 0.000
Z40 Prophylactic surgery
0.874 0.126 0.000
A30-A49 Other bacterial diseases
0.872 0.128 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.868 0.132 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.865 0.135 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.865 0.135 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.865 0.135 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.863 0.137 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.860 0.140 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.858 0.142 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.857 0.143 0.000
H30-H36 Disorders of choroid and retina
0.856 0.144 0.000
N35 Urethral stricture
0.856 0.144 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.853 0.147 0.000
G90-G99 Other disorders of the nervous system
0.850 0.150 0.000
D25 Leiomyoma of uterus
0.849 0.151 0.000
M25.8 Other specified joint disorders
0.849 0.151 0.000
N70 Salpingitis and oophoritis
0.848 0.152 0.000
Z83 Family history of other specific disorders
0.846 0.154 0.000
N73.6 Female pelvic peritoneal adhesions
0.846 0.154 0.000
Z90.2 Acquired absence of lung [part of]
0.846 0.154 0.000
N00-N08 Glomerular diseases
0.844 0.156 0.000
N20-N23 Urolithiasis
0.844 0.156 0.000
N97 Female infertility
0.842 0.158 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.842 0.158 0.000
H10-H13 Disorders of conjunctiva
0.840 0.160 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.838 0.162 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.837 0.163 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.837 0.163 0.000
Z51.1 Chemotherapy session for neoplasm
0.836 0.164 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.836 0.164 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.835 0.165 0.000
H53-H54 Visual disturbances and blindness
0.834 0.166 0.000
Z92 Personal history of medical treatment
0.833 0.167 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.831 0.169 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.830 0.170 0.000
E10-E14 Diabetes mellitus
0.829 0.171 0.000
N75 Diseases of Bartholin's gland
0.827 0.173 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.827 0.173 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.827 0.173 0.000
C78.7 Secondary malignant neoplasm of liver
0.827 0.173 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.826 0.174 0.000
Chapter VIII Diseases of the ear and mastoid process
0.824 0.176 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.824 0.176 0.000
Z93.6 Other artificial openings of urinary tract status
0.822 0.178 0.000
B35-B49 Mycoses
0.820 0.180 0.000
S80-S89 Injuries to the knee and lower leg
0.820 0.180 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.820 0.180 0.000
N93 Other abnormal uterine and vaginal bleeding
0.818 0.182 0.000
Chapter XXII Codes for special purposes
0.809 0.191 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.808 0.192 0.000
Z48 Other surgical follow-up care
0.808 0.192 0.000
N72 Inflammatory disease of cervix uteri
0.807 0.193 0.000
Z93.1 Gastrostomy status
0.806 0.194 0.000
Q61.3 Polycystic kidney, unspecified
0.806 0.194 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.804 0.196 0.000
M25.5 Pain in joint
0.804 0.196 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.802 0.198 0.000
H55-H59 Other disorders of eye and adnexa
0.801 0.199 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.800 0.200 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.800 0.200 0.000
N30.1 Interstitial cystitis (chronic)
0.800 0.200 0.000
N76.6 Ulceration of vulva
0.800 0.200 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.798 0.202 0.000
G40-G47 Episodic and paroxysmal disorders
0.795 0.205 0.000
C50.9 Breast, unspecified
0.795 0.205 0.000
C50.4 Upper-outer quadrant of breast
0.794 0.206 0.000
N17-N19 Renal failure
0.793 0.207 0.000
M70-M79 Other soft tissue disorders
0.790 0.210 0.000
N87 Dysplasia of cervix uteri
0.789 0.211 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.787 0.213 0.000
M20 Acquired deformities of fingers and toes
0.786 0.214 0.000
M65-M68 Disorders of synovium and tendon
0.785 0.215 0.000
N30.9 Cystitis, unspecified
0.784 0.216 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.782 0.218 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.781 0.219 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.780 0.219 0.000
N82 Fistulae involving female genital tract
0.780 0.219 0.000
Y83.9 Surgical procedure, unspecified
0.780 0.220 0.000
A41 Other septicaemia
0.779 0.221 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.778 0.222 0.000
N13.6 Pyonephrosis
0.777 0.223 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.776 0.224 0.000
E10 Insulin-dependent diabetes mellitus
0.775 0.225 0.000
M31 Other necrotising vasculopathies
0.775 0.225 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.775 0.225 0.000
N13.3 Other and unspecified hydronephrosis
0.774 0.226 0.000
N80 Endometriosis
0.774 0.226 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.772 0.228 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.771 0.229 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.771 0.229 0.000
T93 Sequelae of injuries of lower limb
0.771 0.229 0.000
Y83.8 Other surgical procedures
0.771 0.229 0.000
H33 Retinal detachments and breaks
0.771 0.229 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.770 0.230 0.000
M25.86 Other specified joint disorders (Lower leg)
0.769 0.231 0.000
O80-O84 Delivery
0.769 0.231 0.000
H26 Other cataract
0.769 0.231 0.000
S10-S19 Injuries to the neck
0.768 0.232 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.768 0.232 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.768 0.232 0.000
D25.1 Intramural leiomyoma of uterus
0.767 0.233 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.767 0.233 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.766 0.233 0.000
Z85 Personal history of malignant neoplasm
0.767 0.233 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.766 0.234 0.000
N20 Calculus of kidney and ureter
0.765 0.235 0.000
E14 Unspecified diabetes mellitus
0.765 0.235 0.000
N25-N29 Other disorders of kidney and ureter
0.765 0.235 0.000
C50.1 Central portion of breast
0.765 0.235 0.000
D25.0 Submucous leiomyoma of uterus
0.764 0.236 0.000
D22 Melanocytic naevi
0.763 0.237 0.000
T85.2 Mechanical complication of intraocular lens
0.761 0.239 0.000
N11 Chronic tubulo-interstitial nephritis
0.761 0.239 0.000
N35.9 Urethral stricture, unspecified
0.759 0.241 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.759 0.241 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.758 0.242 0.000
N10 Acute tubulo-interstitial nephritis
0.757 0.243 0.000
Z98.0 Intestinal bypass and anastomosis status
0.756 0.244 0.000
H25 Senile cataract
0.755 0.245 0.000
N76.0 Acute vaginitis
0.755 0.245 0.000
Z41 Procedures for purposes other than remedying health state
0.755 0.245 0.000
Z89 Acquired absence of limb
0.755 0.245 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.754 0.246 0.000
S60-S69 Injuries to the wrist and hand
0.754 0.246 0.000
Q61.0 Congenital single renal cyst
0.752 0.248 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.752 0.248 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.752 0.248 0.000
Y88 Sequelae of surgical and medical care as external cause
0.750 0.250 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.749 0.251 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.749 0.251 0.000
Z90.8 Acquired absence of other organs
0.747 0.253 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.747 0.253 0.000
N32.9 Bladder disorder, unspecified
0.746 0.254 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.746 0.254 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.746 0.254 0.000
Z93.5 Cystostomy status
0.746 0.254 0.000
N97.9 Female infertility, unspecified
0.744 0.256 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.744 0.256 0.000
S42 Fracture of shoulder and upper arm
0.743 0.257 0.000
G93 Other disorders of brain
0.743 0.257 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.742 0.258 0.000
N94.1 Dyspareunia
0.741 0.259 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.741 0.259 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.740 0.260 0.000
N99-N99 Other disorders of the genitourinary system
0.739 0.261 0.000
N76.8 Other specified inflammation of vagina and vulva
0.739 0.261 0.000
S90-S99 Injuries to the ankle and foot
0.737 0.262 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.737 0.263 0.000
V80-V89 Other land transport accidents
0.737 0.263 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.737 0.263 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.732 0.268 0.000
V20-V29 Motorcycle rider injured in transport accident
0.732 0.268 0.000
C51-C58 Malignant neoplasms of female genital organs
0.732 0.268 0.000
C50.0 Nipple and areola
0.731 0.269 0.000
Z98.8 Other specified postsurgical states
0.731 0.269 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.731 0.269 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.730 0.270 0.000
C80 Malignant neoplasm without specification of site
0.730 0.270 0.000
T90 Sequelae of injuries of head
0.728 0.272 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.727 0.273 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.727 0.273 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.726 0.273 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.726 0.274 0.000
G43 Migraine
0.724 0.276 0.000
Z51.3 Blood transfusion without reported diagnosis
0.724 0.276 0.000
T66-T78 Other and unspecified effects of external causes
0.722 0.278 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.721 0.279 0.000
S00-S09 Injuries to the head
0.721 0.279 0.000
Q61.2 Polycystic kidney, adult type
0.720 0.280 0.000
M25.53 Pain in joint (Forearm)
0.719 0.281 0.000
C50.2 Upper-inner quadrant of breast
0.719 0.281 0.000
Z43 Attention to artificial openings
0.718 0.282 0.000
Z90.0 Acquired absence of part of head and neck
0.718 0.282 0.000
Y85 Sequelae of transport accidents
0.717 0.283 0.000
Z83.3 Family history of diabetes mellitus
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T81.9 Unspecified complication of procedure
0.717 0.283 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.717 0.283 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.717 0.283 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.717 0.283 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.717 0.283 0.000
Q00-Q07 Congenital malformations of the nervous system
0.716 0.284 0.000
M80-M85 Disorders of bone density and structure
0.716 0.284 0.000
H40-H42 Glaucoma
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.715 0.285 0.000
N71 Inflammatory disease of uterus, except cervix
0.715 0.285 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.715 0.285 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.715 0.285 0.000
D27 Benign neoplasm of ovary
0.714 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
T98 Sequelae of other and unspecified effects of external causes
0.714 0.286 0.000
O60-O75 Complications of labour and delivery
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.286 0.000
W00-W19 Falls
0.713 0.287 0.000
D00-D09 In situ neoplasms
0.713 0.287 0.000
W20-W49 Exposure to inanimate mechanical forces
0.712 0.288 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.712 0.288 0.000
N37 Urethral disorders in diseases classified elsewhere
0.711 0.289 0.000
N34 Urethritis and urethral syndrome
0.711 0.289 0.000
N33 Bladder disorders in diseases classified elsewhere
0.711 0.289 0.000
M25.4 Effusion of joint
0.711 0.289 0.000
Z90.1 Acquired absence of breast(s)
0.710 0.290 0.000
N32.1 Vesicointestinal fistula
0.710 0.290 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.710 0.290 0.000
Z90.7 Acquired absence of genital organ(s)
0.709 0.291 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.709 0.291 0.000
M79.6 Pain in limb
0.707 0.293 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.707 0.293 0.000
H10 Conjunctivitis
0.707 0.293 0.000
H25.1 Senile nuclear cataract
0.707 0.293 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.706 0.294 0.000
Z93.3 Colostomy status
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
G37 Other demyelinating diseases of central nervous system
0.706 0.294 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.706 0.294 0.000
Y83.5 Amputation of limb(s)
0.706 0.294 0.000
Y83.0 Surgical operation with transplant of whole organ
0.706 0.294 0.000
N94.3 Premenstrual tension syndrome
0.706 0.294 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.705 0.295 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
D11 Benign neoplasm of major salivary glands
0.703 0.297 0.000
Q50-Q56 Congenital malformations of genital organs
0.703 0.297 0.000
B37 Candidiasis
0.702 0.298 0.000
Z98.1 Arthrodesis status
0.702 0.298 0.000
N98 Complications associated with artificial fertilisation
0.702 0.298 0.000
N91 Absent, scanty and rare menstruation
0.702 0.298 0.000
N96 Habitual aborter
0.702 0.298 0.000
E14.9 Without complications
0.701 0.299 0.000
T92 Sequelae of injuries of upper limb
0.700 0.300 0.000
G70-G73 Diseases of myoneural junction and muscle
0.700 0.300 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.700 0.300 0.000
Z48.8 Other specified surgical follow-up care
0.699 0.301 0.000
H33.2 Serous retinal detachment
0.699 0.301 0.000
O85-O92 Complications predominantly related to the puerperium
0.699 0.301 0.000
G96 Other disorders of central nervous system
0.699 0.301 0.000
O82 Single delivery by Caesarean section
0.698 0.302 0.000
N94.6 Dysmenorrhoea, unspecified
0.698 0.302 0.000
Chapter X Diseases of the respiratory system
0.698 0.302 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.697 0.303 0.000
N15 Other renal tubulo-interstitial diseases
0.697 0.303 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.697 0.303 0.000
D17 Benign lipomatous neoplasm
0.696 0.304 0.000
Z54 Convalescence
0.696 0.304 0.000
Z52 Donors of organs and tissues
0.696 0.304 0.000
Z44 Fitting and adjustment of external prosthetic device
0.696 0.304 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.696 0.304 0.000
Z93.2 Ileostomy status
0.696 0.304 0.000
D32 Benign neoplasm of meninges
0.695 0.305 0.000
Z49 Care involving dialysis
0.695 0.305 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.694 0.306 0.000
N76.5 Ulceration of vagina
0.694 0.306 0.000
N76.3 Subacute and chronic vulvitis
0.694 0.306 0.000
N76.2 Acute vulvitis
0.694 0.306 0.000
N76.1 Subacute and chronic vaginitis
0.694 0.306 0.000
C15-C26 Malignant neoplasms of digestive organs
0.694 0.306 0.000
Z84 Family history of other conditions
0.693 0.307 0.000
Z81 Family history of mental and behavioural disorders
0.693 0.307 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.693 0.307 0.000
Z80 Family history of malignant neoplasm
0.692 0.308 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.692 0.308 0.000
Q63 Other congenital malformations of kidney
0.692 0.308 0.000
Y89 Sequelae of other external causes
0.691 0.309 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.691 0.309 0.000
B15-B19 Viral hepatitis
0.691 0.309 0.000
T79-T79 Certain early complications of trauma
0.691 0.309 0.000
H54 Blindness and low vision
0.690 0.310 0.000
S60 Superficial injury of wrist and hand
0.690 0.310 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.688 0.312 0.000
N89.7 Haematocolpos
0.688 0.312 0.000
N89.6 Tight hymenal ring
0.688 0.312 0.000
N89.5 Stricture and atresia of vagina
0.688 0.312 0.000
N89.4 Leukoplakia of vagina
0.688 0.312 0.000
N89.3 Dysplasia of vagina, unspecified
0.688 0.312 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.688 0.312 0.000
N89.1 Moderate vaginal dysplasia
0.688 0.312 0.000
N89.0 Mild vaginal dysplasia
0.688 0.312 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.687 0.312 0.000
Q80-Q89 Other congenital malformations
0.687 0.312 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.687 0.312 0.000
Q35-Q37 Cleft lip and cleft palate
0.687 0.312 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.687 0.312 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.687 0.312 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.687 0.313 0.000
Y83.3 Surgical operation with formation of external stoma
0.686 0.313 0.000
Z83.5 Family history of eye and ear disorders
0.686 0.314 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.686 0.314 0.000
Z51.9 Medical care, unspecified
0.686 0.314 0.000
Z51.6 Desensitisation to allergens
0.686 0.314 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.685 0.315 0.000
N32.4 Rupture of bladder, nontraumatic
0.683 0.316 0.000
N32.2 Vesical fistula, not elsewhere classified
0.683 0.316 0.000
S20-S29 Injuries to the thorax
0.683 0.317 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.682 0.318 0.000
H60-H62 Diseases of external ear
0.682 0.318 0.000
G30-G32 Other degenerative diseases of the nervous system
0.681 0.318 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.681 0.319 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.679 0.321 0.000
S86 Injury of muscle and tendon at lower leg level
0.678 0.322 0.000
S50-S59 Injuries to the elbow and forearm
0.677 0.323 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.677 0.323 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.677 0.323 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.677 0.323 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.677 0.323 0.000
N36 Other disorders of urethra
0.677 0.323 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.676 0.324 0.000
N20.1 Calculus of ureter
0.676 0.324 0.000
M91-M94 Chondropathies
0.675 0.324 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.675 0.325 0.000
C50.6 Axillary tail of breast
0.675 0.325 0.000
Z93.9 Artificial opening status, unspecified
0.674 0.326 0.000
Z93.8 Other artificial opening status
0.674 0.326 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.673 0.327 0.000
C78.2 Secondary malignant neoplasm of pleura
0.673 0.327 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.673 0.327 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.673 0.327 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.673 0.327 0.000
G43.9 Migraine, unspecified
0.673 0.327 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.672 0.327 0.000
Z45 Adjustment and management of implanted device
0.672 0.328 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.671 0.329 0.000
M60-M63 Disorders of muscles
0.671 0.329 0.000
M00-M03 Infectious arthropathies
0.671 0.329 0.000
S40 Superficial injury of shoulder and upper arm
0.671 0.329 0.000
D25.2 Subserosal leiomyoma of uterus
0.670 0.329 0.000
Z51.0 Radiotherapy session
0.670 0.330 0.000
D46 Myelodysplastic syndromes
0.670 0.330 0.000
E10.9 Without complications
0.669 0.331 0.000
X60-X84 Intentional self-harm
0.669 0.331 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.668 0.331 0.000
L84 Corns and callosities
0.667 0.333 0.000
D34 Benign neoplasm of thyroid gland
0.667 0.333 0.000
C77.0 Lymph nodes of head, face and neck
0.666 0.334 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.666 0.334 0.000
N13.8 Other obstructive and reflux uropathy
0.666 0.334 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.666 0.334 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.666 0.334 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.665 0.335 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.665 0.335 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.665 0.335 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.665 0.335 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.664 0.336 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.664 0.336 0.000
S82 Fracture of lower leg, including ankle
0.663 0.337 0.000
Z93.0 Tracheostomy status
0.662 0.337 0.000
N75.1 Abscess of Bartholin's gland
0.662 0.338 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.661 0.339 0.000
N90.7 Vulvar cyst
0.661 0.339 0.000
A49 Bacterial infection of unspecified site
0.660 0.340 0.000
M21 Other acquired deformities of limbs
0.660 0.340 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.660 0.340 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.660 0.340 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.659 0.340 0.000
J30-J39 Other diseases of upper respiratory tract
0.659 0.341 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.659 0.341 0.000
N94.5 Secondary dysmenorrhoea
0.659 0.341 0.000
N94.4 Primary dysmenorrhoea
0.659 0.341 0.000
N94.2 Vaginismus
0.659 0.341 0.000
N94.0 Mittelschmerz
0.659 0.341 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.659 0.341 0.000
M34 Systemic sclerosis
0.659 0.341 0.000
M33 Dermatopolymyositis
0.659 0.341 0.000
M32 Systemic lupus erythematosus
0.659 0.341 0.000
M30 Polyarteritis nodosa and related conditions
0.659 0.341 0.000
N13.4 Hydroureter
0.659 0.341 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.658 0.342 0.000
H53 Visual disturbances
0.658 0.342 0.000
H35 Other retinal disorders
0.658 0.342 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.657 0.342 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.657 0.342 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.657 0.342 0.000
N18 Chronic renal failure
0.657 0.343 0.000
Q64 Other congenital malformations of urinary system
0.657 0.343 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.657 0.343 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.657 0.343 0.000
M67 Other disorders of synovium and tendon
0.657 0.343 0.000
C73 Malignant neoplasm of thyroid gland
0.657 0.343 0.000
H11 Other disorders of conjunctiva
0.656 0.344 0.000
N05 Unspecified nephritic syndrome
0.655 0.345 0.000
N93.0 Postcoital and contact bleeding
0.655 0.345 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.655 0.345 0.000
N75.0 Cyst of Bartholin's gland
0.655 0.345 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.655 0.345 0.000
N70.1 Chronic salpingitis and oophoritis
0.654 0.346 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.654 0.346 0.000
T95 Sequelae of burns, corrosions and frostbite
0.654 0.346 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.654 0.346 0.000
T91 Sequelae of injuries of neck and trunk
0.654 0.346 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.654 0.346 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.654 0.346 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.653 0.347 0.000
B25-B34 Other viral diseases
0.652 0.347 0.000
N90.4 Leukoplakia of vulva
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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