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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77282176
log Bayes Factor = 20.0294
Chromosome 13   position 85,917,626  (GRCh37) Explore rs77282176 on Ensembl!
Variant rs77282176 is part of Cluster X0268

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.997 0.003 0.000
Chapter II Neoplasms
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.995 0.005 0.000
K70-K77 Diseases of liver
0.994 0.006 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.993 0.007 0.000
M50-M54 Other dorsopathies
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
L03 Cellulitis
0.990 0.010 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.990 0.010 0.000
M54 Dorsalgia
0.989 0.011 0.000
K83 Other diseases of biliary tract
0.989 0.011 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.988 0.012 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.981 0.019 0.000
A30-A49 Other bacterial diseases
0.979 0.021 0.000
M54.5 Low back pain
0.975 0.025 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.974 0.026 0.000
C79 Secondary malignant neoplasm of other sites
0.970 0.030 0.000
I50 Heart failure
0.968 0.032 0.000
K90-K93 Other diseases of the digestive system
0.967 0.033 0.000
R26 Abnormalities of gait and mobility
0.966 0.034 0.000
A00-A09 Intestinal infectious diseases
0.965 0.035 0.000
L03.1 Cellulitis of other parts of limb
0.964 0.036 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.964 0.036 0.000
A41 Other septicaemia
0.961 0.039 0.000
K83.8 Other specified diseases of biliary tract
0.959 0.041 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.956 0.044 0.000
I95 Hypotension
0.954 0.046 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.947 0.053 0.000
Chapter X Diseases of the respiratory system
0.947 0.053 0.000
E86 Volume depletion
0.945 0.055 0.000
E20-E35 Disorders of other endocrine glands
0.944 0.056 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.937 0.063 0.000
K76 Other diseases of liver
0.936 0.064 0.000
E87.6 Hypokalaemia
0.936 0.064 0.000
A41.9 Septicaemia, unspecified
0.931 0.069 0.000
I50.1 Left ventricular failure
0.930 0.070 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.929 0.071 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.928 0.072 0.000
I50.9 Heart failure, unspecified
0.924 0.076 0.000
B95-B98 Bacterial, viral and other infectious agents
0.920 0.080 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.920 0.080 0.000
I95.1 Orthostatic hypotension
0.918 0.082 0.000
J90-J94 Other diseases of pleura
0.917 0.083 0.000
K70 Alcoholic liver disease
0.917 0.083 0.000
L03.9 Cellulitis, unspecified
0.917 0.083 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.914 0.086 0.000
K83.1 Obstruction of bile duct
0.913 0.087 0.000
C15-C26 Malignant neoplasms of digestive organs
0.903 0.097 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.902 0.098 0.000
K65-K67 Diseases of peritoneum
0.902 0.098 0.000
R50-R69 General symptoms and signs
0.901 0.099 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.897 0.103 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.896 0.104 0.000
T81 Complications of procedures, not elsewhere classified
0.894 0.106 0.000
S00-S09 Injuries to the head
0.893 0.107 0.000
R79 Other abnormal findings of blood chemistry
0.893 0.107 0.000
Chapter VI Diseases of the nervous system
0.888 0.112 0.000
C77.3 Axillary and upper limb lymph nodes
0.887 0.113 0.000
R15 Faecal incontinence
0.885 0.115 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.885 0.115 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.884 0.116 0.000
E87.2 Acidosis
0.883 0.117 0.000
K81 Cholecystitis
0.883 0.117 0.000
J09-J18 Influenza and pneumonia
0.882 0.118 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.880 0.120 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.880 0.120 0.000
K50-K52 Noninfective enteritis and colitis
0.880 0.120 0.000
M54.57 Low back pain (Lumbosacral region)
0.878 0.122 0.000
K86 Other diseases of pancreas
0.877 0.123 0.000
J90 Pleural effusion, not elsewhere classified
0.876 0.124 0.000
K76.6 Portal hypertension
0.875 0.125 0.000
R51 Headache
0.875 0.125 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.873 0.127 0.000
L05 Pilonidal cyst
0.871 0.129 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.867 0.133 0.000
T66-T78 Other and unspecified effects of external causes
0.866 0.134 0.000
L03.3 Cellulitis of trunk
0.865 0.135 0.000
M80-M85 Disorders of bone density and structure
0.865 0.135 0.000
E87.0 Hyperosmolality and hypernatraemia
0.862 0.138 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.862 0.138 0.000
M54.3 Sciatica
0.861 0.139 0.000
Chapter VIII Diseases of the ear and mastoid process
0.861 0.139 0.000
M51 Other intervertebral disk disorders
0.856 0.144 0.000
I95.9 Hypotension, unspecified
0.856 0.144 0.000
M54.56 Low back pain (Lumbar region)
0.852 0.148 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.852 0.148 0.000
S80-S89 Injuries to the knee and lower leg
0.852 0.148 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.850 0.150 0.000
E27 Other disorders of adrenal gland
0.848 0.152 0.000
K66 Other disorders of peritoneum
0.847 0.153 0.000
M20-M25 Other joint disorders
0.844 0.156 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.842 0.158 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.842 0.158 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.842 0.158 0.000
K92 Other diseases of digestive system
0.837 0.163 0.000
C50-C50 Malignant neoplasm of breast
0.837 0.163 0.000
L03.8 Cellulitis of other sites
0.837 0.163 0.000
K83.9 Disease of biliary tract, unspecified
0.834 0.166 0.000
R18 Ascites
0.834 0.166 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.832 0.168 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.832 0.168 0.000
K82 Other diseases of gallbladder
0.831 0.169 0.000
E88 Other metabolic disorders
0.830 0.170 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.830 0.170 0.000
E87.5 Hyperkalaemia
0.827 0.173 0.000
K72 Hepatic failure, not elsewhere classified
0.825 0.175 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.825 0.175 0.000
L20-L30 Dermatitis and eczema
0.825 0.175 0.000
Chapter VII Diseases of the eye and adnexa
0.823 0.177 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.823 0.177 0.000
Chapter XIV Diseases of the genitourinary system
0.822 0.178 0.000
R27 Other lack of coordination
0.821 0.179 0.000
K75 Other inflammatory liver diseases
0.820 0.179 0.000
S40-S49 Injuries to the shoulder and upper arm
0.819 0.181 0.000
S90-S99 Injuries to the ankle and foot
0.817 0.183 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.817 0.183 0.000
M54.9 Dorsalgia, unspecified
0.815 0.185 0.000
I51 Complications and ill-defined descriptions of heart disease
0.814 0.186 0.000
H65-H75 Diseases of middle ear and mastoid
0.813 0.187 0.000
M35 Other systemic involvement of connective tissue
0.813 0.187 0.000
J18 Pneumonia, organism unspecified
0.810 0.190 0.000
M54.59 Low back pain (Site unspecified)
0.810 0.190 0.000
K81.9 Cholecystitis, unspecified
0.809 0.191 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.806 0.194 0.000
S01 Open wound of head
0.806 0.194 0.000
E87.7 Fluid overload
0.806 0.194 0.000
K90 Intestinal malabsorption
0.806 0.194 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.804 0.196 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.804 0.196 0.000
M05-M14 Inflammatory polyarthropathies
0.803 0.197 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.803 0.197 0.000
C79.2 Secondary malignant neoplasm of skin
0.802 0.198 0.000
L50-L54 Urticaria and erythema
0.801 0.199 0.000
K70.9 Alcoholic liver disease, unspecified
0.801 0.199 0.000
I42 Cardiomyopathy
0.800 0.200 0.000
K66.0 Peritoneal adhesions
0.800 0.200 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.800 0.200 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.797 0.203 0.000
R26.3 Immobility
0.797 0.203 0.000
I33 Acute and subacute endocarditis
0.796 0.204 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.795 0.205 0.000
E78.5 Hyperlipidaemia, unspecified
0.795 0.205 0.000
M86-M90 Other osteopathies
0.791 0.209 0.000
M54.4 Lumbago with sciatica
0.791 0.209 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.789 0.211 0.000
C77.2 Intra-abdominal lymph nodes
0.789 0.211 0.000
K76.8 Other specified diseases of liver
0.786 0.214 0.000
J18.9 Pneumonia, unspecified
0.786 0.214 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.785 0.214 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.785 0.215 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.784 0.216 0.000
M35.3 Polymyalgia rheumatica
0.783 0.217 0.000
R26.0 Ataxic gait
0.781 0.219 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.781 0.219 0.000
A08 Viral and other specified intestinal infections
0.780 0.220 0.000
I34 Nonrheumatic mitral valve disorders
0.779 0.220 0.000
B65-B83 Helminthiases
0.779 0.221 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.777 0.223 0.000
R53 Malaise and fatigue
0.775 0.225 0.000
K91.3 Postoperative intestinal obstruction
0.774 0.225 0.000
C77.9 Lymph node, unspecified
0.773 0.227 0.000
K74 Fibrosis and cirrhosis of liver
0.772 0.228 0.000
T78 Adverse effects, not elsewhere classified
0.772 0.228 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.771 0.229 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.769 0.231 0.000
R54 Senility
0.769 0.231 0.000
K51 Ulcerative colitis
0.768 0.232 0.000
S01.9 Open wound of head, part unspecified
0.767 0.233 0.000
I05-I09 Chronic rheumatic heart diseases
0.767 0.233 0.000
S10-S19 Injuries to the neck
0.767 0.233 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.767 0.233 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.765 0.235 0.000
B35-B49 Mycoses
0.765 0.235 0.000
A49 Bacterial infection of unspecified site
0.764 0.236 0.000
C80 Malignant neoplasm without specification of site
0.762 0.238 0.000
C78.0 Secondary malignant neoplasm of lung
0.761 0.239 0.000
K86.2 Cyst of pancreas
0.761 0.239 0.000
D50-D53 Nutritional anaemias
0.758 0.242 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.752 0.248 0.000
M54.50 Low back pain (Multiple sites in spine)
0.751 0.249 0.000
G90-G99 Other disorders of the nervous system
0.751 0.249 0.000
L05.9 Pilonidal cyst without abscess
0.751 0.249 0.000
G40-G47 Episodic and paroxysmal disorders
0.750 0.250 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.748 0.252 0.000
J94 Other pleural conditions
0.746 0.254 0.000
E21.0 Primary hyperparathyroidism
0.745 0.255 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.745 0.255 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.745 0.255 0.000
R42 Dizziness and giddiness
0.743 0.257 0.000
C77.1 Intrathoracic lymph nodes
0.743 0.257 0.000
R94 Abnormal results of function studies
0.742 0.258 0.000
K76.9 Liver disease, unspecified
0.742 0.258 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.741 0.259 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.741 0.259 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.741 0.259 0.000
J60-J70 Lung diseases due to external agents
0.740 0.260 0.000
L08 Other local infections of skin and subcutaneous tissue
0.740 0.260 0.000
D00-D09 In situ neoplasms
0.740 0.260 0.000
E50-E64 Other nutritional deficiencies
0.740 0.260 0.000
R21 Rash and other nonspecific skin eruption
0.740 0.260 0.000
J92 Pleural plaque
0.740 0.260 0.000
K92.9 Disease of digestive system, unspecified
0.739 0.261 0.000
K85 Acute pancreatitis
0.738 0.262 0.000
C15 Malignant neoplasm of oesophagus
0.738 0.262 0.000
R16.1 Splenomegaly, not elsewhere classified
0.738 0.262 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.737 0.263 0.000
Chapter XXII Codes for special purposes
0.736 0.264 0.000
R17 Unspecified jaundice
0.736 0.264 0.000
M53 Other dorsopathies, not elsewhere classified
0.735 0.265 0.000
S06 Intracranial injury
0.734 0.266 0.000
I30 Acute pericarditis
0.733 0.267 0.000
I35 Nonrheumatic aortic valve disorders
0.733 0.267 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.732 0.268 0.000
A41.8 Other specified septicaemia
0.731 0.269 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.731 0.269 0.000
K50 Crohn's disease [regional enteritis]
0.731 0.269 0.000
L30 Other dermatitis
0.730 0.270 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.730 0.270 0.000
K35-K38 Diseases of appendix
0.730 0.270 0.000
B15-B19 Viral hepatitis
0.729 0.270 0.000
N00-N08 Glomerular diseases
0.729 0.271 0.000
K81.0 Acute cholecystitis
0.728 0.272 0.000
S00 Superficial injury of head
0.728 0.272 0.000
K70.3 Alcoholic cirrhosis of liver
0.725 0.275 0.000
R13 Dysphagia
0.725 0.275 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.724 0.276 0.000
C50 Malignant neoplasm of breast
0.724 0.276 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.722 0.278 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.722 0.278 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.720 0.280 0.000
H66 Suppurative and unspecified otitis media
0.720 0.280 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.719 0.281 0.000
I99 Other and unspecified disorders of circulatory system
0.718 0.281 0.000
M54.39 Sciatica (Site unspecified)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M54.1 Radiculopathy
0.717 0.283 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
J91 Pleural effusion in conditions classified elsewhere
0.716 0.284 0.000
I46 Cardiac arrest
0.716 0.284 0.000
S60-S69 Injuries to the wrist and hand
0.716 0.284 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
R57 Shock, not elsewhere classified
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
L10-L14 Bullous disorders
0.714 0.286 0.000
C25 Malignant neoplasm of pancreas
0.714 0.286 0.000
H40-H42 Glaucoma
0.713 0.286 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.713 0.287 0.000
K77 Liver disorders in diseases classified elsewhere
0.712 0.288 0.000
K73 Chronic hepatitis, not elsewhere classified
0.712 0.288 0.000
K71 Toxic liver disease
0.712 0.288 0.000
L04 Acute lymphadenitis
0.712 0.288 0.000
L01 Impetigo
0.712 0.288 0.000
L00 Staphylococcal scalded skin syndrome
0.712 0.288 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.712 0.288 0.000
M81 Osteoporosis without pathological fracture
0.712 0.288 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.711 0.289 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
R60 Oedema, not elsewhere classified
0.710 0.290 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.710 0.290 0.000
S70-S79 Injuries to the hip and thigh
0.710 0.290 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.710 0.290 0.000
E87.4 Mixed disorder of acid-base balance
0.710 0.290 0.000
E87.3 Alkalosis
0.710 0.290 0.000
E27.1 Primary adrenocortical insufficiency
0.710 0.290 0.000
M54.8 Other dorsalgia
0.709 0.291 0.000
M54.6 Pain in thoracic spine
0.709 0.291 0.000
M54.0 Panniculitis affecting regions of neck and back
0.709 0.291 0.000
K70.1 Alcoholic hepatitis
0.709 0.291 0.000
K83.5 Biliary cyst
0.709 0.291 0.000
K83.4 Spasm of sphincter of Oddi
0.709 0.291 0.000
K83.3 Fistula of bile duct
0.709 0.291 0.000
K83.2 Perforation of bile duct
0.709 0.291 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.709 0.291 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.709 0.291 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.708 0.292 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.708 0.292 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.708 0.292 0.000
K70.4 Alcoholic hepatic failure
0.708 0.292 0.000
M54.2 Cervicalgia
0.706 0.294 0.000
M54.36 Sciatica (Lumbar region)
0.705 0.295 0.000
R25 Abnormal involuntary movements
0.705 0.295 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.704 0.296 0.000
I52 Other heart disorders in diseases classified elsewhere
0.703 0.297 0.000
I48 Atrial fibrillation and flutter
0.703 0.297 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.703 0.297 0.000
I41 Myocarditis in diseases classified elsewhere
0.703 0.297 0.000
I40 Acute myocarditis
0.703 0.297 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.703 0.297 0.000
I37 Pulmonary valve disorders
0.703 0.297 0.000
I36 Nonrheumatic tricuspid valve disorders
0.703 0.297 0.000
I32 Pericarditis in diseases classified elsewhere
0.703 0.297 0.000
H74 Other disorders of middle ear and mastoid
0.702 0.297 0.000
A48 Other bacterial diseases, not elsewhere classified
0.702 0.298 0.000
A44 Bartonellosis
0.702 0.298 0.000
A43 Nocardiosis
0.702 0.298 0.000
A42 Actinomycosis
0.702 0.298 0.000
A40 Streptococcal septicaemia
0.702 0.298 0.000
A39 Meningococcal infection
0.702 0.298 0.000
A37 Whooping cough
0.702 0.298 0.000
A36 Diphtheria
0.702 0.298 0.000
A32 Listeriosis
0.702 0.298 0.000
A31 Infection due to other mycobacteria
0.702 0.298 0.000
A30 Leprosy [Hansen's disease]
0.702 0.298 0.000
A46 Erysipelas
0.702 0.298 0.000
A38 Scarlet fever
0.702 0.298 0.000
A35 Other tetanus
0.702 0.298 0.000
A34 Obstetrical tetanus
0.702 0.298 0.000
A33 Tetanus neonatorum
0.702 0.298 0.000
S80 Superficial injury of lower leg
0.701 0.299 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.701 0.299 0.000
M54.55 Low back pain (Thoracolumbar region)
0.699 0.301 0.000
M54.54 Low back pain-Thoracic
0.699 0.301 0.000
M54.53 Low back pain-Cervicothoracic
0.699 0.301 0.000
M54.52 Low back pain-Cervical
0.699 0.301 0.000
M54.51 Low back pain-Occipit-atl-axl
0.699 0.301 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.699 0.301 0.000
M25 Other joint disorders, not elsewhere classified
0.699 0.301 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.698 0.302 0.000
A04 Other bacterial intestinal infections
0.698 0.302 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.697 0.303 0.000
D60-D64 Aplastic and other anaemias
0.696 0.303 0.000
C79.6 Secondary malignant neoplasm of ovary
0.695 0.305 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.695 0.305 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.695 0.305 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.695 0.305 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.695 0.305 0.000
E21.3 Hyperparathyroidism, unspecified
0.695 0.305 0.000
M40-M43 Deforming dorsopathies
0.695 0.305 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.695 0.305 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.694 0.306 0.000
L40-L45 Papulosquamous disorders
0.694 0.306 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.694 0.306 0.000
R74 Abnormal serum enzyme levels
0.693 0.306 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.693 0.307 0.000
R26.1 Paralytic gait
0.693 0.307 0.000
Chapter V Mental and behavioural disorders
0.693 0.307 0.000
I49 Other cardiac arrhythmias
0.693 0.307 0.000
K82.8 Other specified diseases of gallbladder
0.692 0.308 0.000
A07 Other protozoal intestinal diseases
0.692 0.308 0.000
A06 Amoebiasis
0.692 0.308 0.000
A05 Other bacterial foodborne intoxications
0.692 0.308 0.000
A03 Shigellosis
0.692 0.308 0.000
A02 Other Salmonella infections
0.692 0.308 0.000
A01 Typhoid and paratyphoid fevers
0.692 0.308 0.000
A00 Cholera
0.692 0.308 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.691 0.309 0.000
T79-T79 Certain early complications of trauma
0.691 0.309 0.000
L05.0 Pilonidal cyst with abscess
0.691 0.309 0.000
S42 Fracture of shoulder and upper arm
0.691 0.309 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.691 0.309 0.000
K90.0 Coeliac disease
0.690 0.310 0.000
S20-S29 Injuries to the thorax
0.690 0.310 0.000
A41.4 Septicaemia due to anaerobes
0.689 0.311 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.689 0.311 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.689 0.311 0.000
I51.7 Cardiomegaly
0.689 0.311 0.000
S92 Fracture of foot, except ankle
0.689 0.311 0.000
E28 Ovarian dysfunction
0.689 0.311 0.000
I71 Aortic aneurysm and dissection
0.689 0.311 0.000
K86.8 Other specified diseases of pancreas
0.688 0.312 0.000
C77.0 Lymph nodes of head, face and neck
0.687 0.312 0.000
K92.0 Haematemesis
0.687 0.313 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.686 0.314 0.000
C77.8 Lymph nodes of multiple regions
0.685 0.315 0.000
C77.4 Inguinal and lower limb lymph nodes
0.685 0.315 0.000
S81 Open wound of lower leg
0.685 0.315 0.000
I95.8 Other hypotension
0.684 0.316 0.000
I95.0 Idiopathic hypotension
0.684 0.316 0.000
K72.0 Acute and subacute hepatic failure
0.682 0.318 0.000
D72 Other disorders of white blood cells
0.682 0.318 0.000
C16 Malignant neoplasm of stomach
0.681 0.319 0.000
E00-E07 Disorders of thyroid gland
0.680 0.320 0.000
M84 Disorders of continuity of bone
0.680 0.320 0.000
K91.4 Colostomy and enterostomy malfunction
0.678 0.322 0.000
M51.8 Other specified intervertebral disk disorders
0.677 0.323 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.677 0.323 0.000
E34 Other endocrine disorders
0.677 0.323 0.000
E32 Diseases of thymus
0.677 0.323 0.000
E31 Polyglandular dysfunction
0.677 0.323 0.000
E30 Disorders of puberty, not elsewhere classified
0.677 0.323 0.000
E29 Testicular dysfunction
0.677 0.323 0.000
E26 Hyperaldosteronism
0.677 0.323 0.000
E25 Adrenogenital disorders
0.677 0.323 0.000
E24 Cushing's syndrome
0.677 0.323 0.000
E22 Hyperfunction of pituitary gland
0.677 0.323 0.000
E20 Hypoparathyroidism
0.677 0.323 0.000
M21 Other acquired deformities of limbs
0.677 0.323 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.676 0.324 0.000
M06 Other rheumatoid arthritis
0.676 0.324 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.676 0.324 0.000
M50 Cervical disk disorders
0.675 0.325 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.675 0.325 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.673 0.327 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.672 0.328 0.000
R77 Other abnormalities of plasma proteins
0.672 0.328 0.000
R76 Other abnormal immunological findings in serum
0.672 0.328 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.672 0.328 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.672 0.328 0.000
R71 Abnormality of red blood cells
0.672 0.328 0.000
I95.2 Hypotension due to drugs
0.672 0.328 0.000
K76.7 Hepatorenal syndrome
0.671 0.329 0.000
K76.5 Hepatic veno-occlusive disease
0.671 0.329 0.000
K76.4 Peliosis hepatis
0.671 0.329 0.000
K76.3 Infarction of liver
0.671 0.329 0.000
K76.2 Central haemorrhagic necrosis of liver
0.671 0.329 0.000
K76.1 Chronic passive congestion of liver
0.671 0.329 0.000
K92.1 Melaena
0.671 0.329 0.000
J00-J06 Acute upper respiratory infections
0.669 0.331 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.668 0.332 0.000
I38 Endocarditis, valve unspecified
0.668 0.332 0.000
R63 Symptoms and signs concerning food and fluid intake
0.667 0.333 0.000
G70-G73 Diseases of myoneural junction and muscle
0.667 0.333 0.000
M51.2 Other specified intervertebral disk displacement
0.666 0.334 0.000
L03.2 Cellulitis of face
0.666 0.334 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.665 0.334 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.665 0.335 0.000
D45 Polycythaemia vera
0.664 0.336 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.664 0.336 0.000
I33.0 Acute and subacute infective endocarditis
0.664 0.336 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.663 0.337 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.663 0.337 0.000
D47.1 Chronic myeloproliferative disease
0.663 0.337 0.000
N17-N19 Renal failure
0.660 0.340 0.000
D55-D59 Haemolytic anaemias
0.659 0.340 0.000
N60-N64 Disorders of breast
0.658 0.342 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.657 0.342 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.657 0.343 0.000
K70.0 Alcoholic fatty liver
0.657 0.343 0.000
R73 Elevated blood glucose level
0.657 0.343 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.657 0.343 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.657 0.343 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.656 0.344 0.000
I42.6 Alcoholic cardiomyopathy
0.656 0.344 0.000
T87 Complications peculiar to reattachment and amputation
0.655 0.344 0.000
T86 Failure and rejection of transplanted organs and tissues
0.655 0.344 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.655 0.344 0.000
M85 Other disorders of bone density and structure
0.655 0.345 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.655 0.345 0.000
R27.8 Other and unspecified lack of coordination
0.654 0.346 0.000
R27.0 Ataxia, unspecified
0.654 0.346 0.000
S01.5 Open wound of lip and oral cavity
0.653 0.347 0.000
D70 Agranulocytosis
0.653 0.347 0.000
T90 Sequelae of injuries of head
0.652 0.348 0.000
I31 Other diseases of pericardium
0.652 0.348 0.000
H60-H62 Diseases of external ear
0.649 0.351 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.649 0.351 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.648 0.352 0.000
C51-C58 Malignant neoplasms of female genital organs
0.648 0.352 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.648 0.352 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.648 0.352 0.000
C21 Malignant neoplasm of anus and anal canal
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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