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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77411293
log Bayes Factor = 13.9361
Chromosome 6   position 46,467,013  (GRCh37) Explore rs77411293 on Ensembl!
Variant rs77411293 is part of Cluster X0118

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
F30-F39 Mood [affective] disorders
0.997 0.003 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.996 0.004 0.000
E10 Insulin-dependent diabetes mellitus
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.994 0.006 0.000
K90-K93 Other diseases of the digestive system
0.993 0.007 0.000
F32 Depressive episode
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.992 0.008 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
F32.9 Depressive episode, unspecified
0.988 0.012 0.000
E65-E68 Obesity and other hyperalimentation
0.988 0.012 0.000
Chapter X Diseases of the respiratory system
0.985 0.015 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.985 0.015 0.000
I30-I52 Other forms of heart disease
0.983 0.017 0.000
I71 Aortic aneurysm and dissection
0.983 0.017 0.000
E66 Obesity
0.980 0.020 0.000
I50 Heart failure
0.976 0.024 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.974 0.026 0.000
H36 Retinal disorders in diseases classified elsewhere
0.973 0.027 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.972 0.028 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.971 0.029 0.000
K92 Other diseases of digestive system
0.963 0.037 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.963 0.037 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.963 0.037 0.000
E10.9 Without complications
0.962 0.038 0.000
Chapter VI Diseases of the nervous system
0.961 0.039 0.000
H36.0 Diabetic retinopathy
0.958 0.042 0.000
Chapter XX External causes of morbidity and mortality
0.952 0.048 0.000
I10-I15 Hypertensive diseases
0.949 0.051 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.949 0.051 0.000
E66.8 Other obesity
0.947 0.053 0.000
I50.0 Congestive heart failure
0.945 0.055 0.000
M70-M79 Other soft tissue disorders
0.943 0.057 0.000
K70-K77 Diseases of liver
0.942 0.058 0.000
E11.3 With ophthalmic complications
0.940 0.060 0.000
I12 Hypertensive renal disease
0.938 0.062 0.000
T39.1 4-Aminophenol derivatives
0.935 0.065 0.000
G90-G99 Other disorders of the nervous system
0.935 0.065 0.000
K90 Intestinal malabsorption
0.934 0.066 0.000
M75 Shoulder lesions
0.933 0.067 0.000
E66.9 Obesity, unspecified
0.928 0.072 0.000
J90-J94 Other diseases of pleura
0.927 0.073 0.000
I74 Arterial embolism and thrombosis
0.925 0.075 0.000
M05-M14 Inflammatory polyarthropathies
0.920 0.080 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.920 0.080 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.918 0.082 0.000
I12.0 Hypertensive renal disease with renal failure
0.917 0.083 0.000
H50 Other strabismus
0.916 0.084 0.000
F31 Bipolar affective disorder
0.914 0.086 0.000
I50.1 Left ventricular failure
0.912 0.088 0.000
M75.0 Adhesive capsulitis of shoulder
0.910 0.090 0.000
M13 Other arthritis
0.909 0.091 0.000
K08 Other disorders of teeth and supporting structures
0.908 0.092 0.000
H18 Other disorders of cornea
0.907 0.093 0.000
M13.9 Arthritis, unspecified
0.903 0.097 0.000
E11.9 Without complications
0.902 0.098 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.893 0.107 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.892 0.108 0.000
I51 Complications and ill-defined descriptions of heart disease
0.890 0.110 0.000
E10.3 With ophthalmic complications
0.889 0.111 0.000
K90.0 Coeliac disease
0.888 0.112 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.887 0.113 0.000
E11.5 With peripheral circulatory complications
0.883 0.117 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.882 0.118 0.000
K92.0 Haematemesis
0.880 0.120 0.000
G62 Other polyneuropathies
0.875 0.125 0.000
J20-J22 Other acute lower respiratory infections
0.874 0.126 0.000
T66-T78 Other and unspecified effects of external causes
0.873 0.127 0.000
H21 Other disorders of iris and ciliary body
0.871 0.129 0.000
H33 Retinal detachments and breaks
0.871 0.129 0.000
H52 Disorders of refraction and accommodation
0.871 0.129 0.000
I33 Acute and subacute endocarditis
0.870 0.130 0.000
G95 Other diseases of spinal cord
0.869 0.131 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.869 0.131 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.866 0.134 0.000
K74 Fibrosis and cirrhosis of liver
0.866 0.134 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.866 0.134 0.000
J09-J18 Influenza and pneumonia
0.863 0.137 0.000
K92.1 Melaena
0.861 0.139 0.000
H20 Iridocyclitis
0.860 0.140 0.000
I85 Oesophageal varices
0.860 0.140 0.000
K08.3 Retained dental root
0.857 0.143 0.000
E10.2 With renal complications
0.854 0.146 0.000
S70-S79 Injuries to the hip and thigh
0.852 0.148 0.000
J60-J70 Lung diseases due to external agents
0.841 0.159 0.000
G62.9 Polyneuropathy, unspecified
0.840 0.160 0.000
H35 Other retinal disorders
0.839 0.161 0.000
I71.0 Dissection of aorta [any part]
0.838 0.162 0.000
I73 Other peripheral vascular diseases
0.838 0.162 0.000
I12.9 Hypertensive renal disease without renal failure
0.838 0.162 0.000
S10-S19 Injuries to the neck
0.835 0.165 0.000
H18.5 Hereditary corneal dystrophies
0.832 0.168 0.000
I80 Phlebitis and thrombophlebitis
0.827 0.173 0.000
T79-T79 Certain early complications of trauma
0.826 0.174 0.000
K02 Dental caries
0.826 0.174 0.000
S90-S99 Injuries to the ankle and foot
0.825 0.175 0.000
E10.1 With ketoacidosis
0.824 0.176 0.000
J93 Pneumothorax
0.824 0.176 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.821 0.179 0.000
E14 Unspecified diabetes mellitus
0.818 0.182 0.000
G70-G73 Diseases of myoneural junction and muscle
0.818 0.182 0.000
I20-I25 Ischaemic heart diseases
0.818 0.182 0.000
K04 Diseases of pulp and periapical tissues
0.817 0.183 0.000
F32.1 Moderate depressive episode
0.817 0.183 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.817 0.183 0.000
M91-M94 Chondropathies
0.816 0.184 0.000
K76 Other diseases of liver
0.816 0.184 0.000
F34 Persistent mood [affective] disorders
0.814 0.186 0.000
E10.4 With neurological complications
0.813 0.187 0.000
I85.9 Oesophageal varices without bleeding
0.811 0.189 0.000
H50.1 Divergent concomitant strabismus
0.810 0.190 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.807 0.193 0.000
I46 Cardiac arrest
0.806 0.194 0.000
J22 Unspecified acute lower respiratory infection
0.805 0.195 0.000
J91 Pleural effusion in conditions classified elsewhere
0.803 0.197 0.000
S60-S69 Injuries to the wrist and hand
0.798 0.202 0.000
M80-M85 Disorders of bone density and structure
0.798 0.202 0.000
H33.0 Retinal detachment with retinal break
0.797 0.203 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.797 0.203 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.796 0.204 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.796 0.204 0.000
I45 Other conduction disorders
0.795 0.205 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.792 0.208 0.000
M75.1 Rotator cuff syndrome
0.790 0.210 0.000
I33.0 Acute and subacute infective endocarditis
0.789 0.211 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.785 0.214 0.000
K74.6 Other and unspecified cirrhosis of liver
0.786 0.214 0.000
J92 Pleural plaque
0.785 0.215 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.783 0.217 0.000
H16 Keratitis
0.780 0.220 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.780 0.220 0.000
I47 Paroxysmal tachycardia
0.778 0.222 0.000
K00 Disorders of tooth development and eruption
0.776 0.224 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.776 0.224 0.000
F31.9 Bipolar affective disorder, unspecified
0.774 0.226 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.772 0.227 0.000
Chapter XXII Codes for special purposes
0.772 0.228 0.000
M86-M90 Other osteopathies
0.772 0.228 0.000
H34 Retinal vascular occlusions
0.772 0.228 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.771 0.229 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.771 0.229 0.000
I51.9 Heart disease, unspecified
0.770 0.230 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.770 0.230 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.769 0.230 0.000
H50.5 Heterophoria
0.765 0.235 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.764 0.236 0.000
G95.1 Vascular myelopathies
0.764 0.236 0.000
W20-W49 Exposure to inanimate mechanical forces
0.763 0.237 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.762 0.238 0.000
I70 Atherosclerosis
0.762 0.238 0.000
T78 Adverse effects, not elsewhere classified
0.762 0.238 0.000
K92.9 Disease of digestive system, unspecified
0.761 0.239 0.000
E11.4 With neurological complications
0.760 0.240 0.000
K01 Embedded and impacted teeth
0.760 0.240 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.758 0.242 0.000
J95-J99 Other diseases of the respiratory system
0.758 0.242 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.758 0.242 0.000
M75.4 Impingement syndrome of shoulder
0.757 0.243 0.000
E11.1 With ketoacidosis
0.757 0.243 0.000
S72 Fracture of femur
0.757 0.243 0.000
I50.9 Heart failure, unspecified
0.756 0.244 0.000
K05 Gingivitis and periodontal diseases
0.755 0.245 0.000
J93.9 Pneumothorax, unspecified
0.754 0.246 0.000
G96 Other disorders of central nervous system
0.754 0.246 0.000
Y52 Agents primarily affecting the cardiovascular system
0.753 0.247 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.753 0.247 0.000
M75.2 Bicipital tendinitis
0.752 0.247 0.000
I73.0 Raynaud's syndrome
0.750 0.250 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.749 0.250 0.000
I51.8 Other ill-defined heart diseases
0.749 0.251 0.000
H20.9 Iridocyclitis, unspecified
0.749 0.251 0.000
M71 Other bursopathies
0.748 0.252 0.000
I46.9 Cardiac arrest, unspecified
0.748 0.252 0.000
H10-H13 Disorders of conjunctiva
0.748 0.252 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.747 0.253 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.746 0.254 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.744 0.256 0.000
E11.0 With coma
0.744 0.256 0.000
K40-K46 Hernia
0.742 0.258 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.741 0.259 0.000
H52.1 Myopia
0.740 0.260 0.000
W50-W64 Exposure to animate mechanical forces
0.740 0.260 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.740 0.260 0.000
M84 Disorders of continuity of bone
0.739 0.261 0.000
J00-J06 Acute upper respiratory infections
0.739 0.261 0.000
H21.8 Other specified disorders of iris and ciliary body
0.738 0.262 0.000
I25 Chronic ischaemic heart disease
0.737 0.263 0.000
J94 Other pleural conditions
0.737 0.263 0.000
G90 Disorders of autonomic nervous system
0.735 0.265 0.000
F33 Recurrent depressive disorder
0.735 0.265 0.000
S92 Fracture of foot, except ankle
0.732 0.268 0.000
X60-X84 Intentional self-harm
0.732 0.268 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.731 0.269 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.730 0.270 0.000
F80-F89 Disorders of psychological development
0.730 0.270 0.000
E13 Other specified diabetes mellitus
0.729 0.271 0.000
K02.9 Dental caries, unspecified
0.728 0.272 0.000
I25.2 Old myocardial infarction
0.728 0.272 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.727 0.273 0.000
K73 Chronic hepatitis, not elsewhere classified
0.727 0.273 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.726 0.274 0.000
T39.0 Salicylates
0.725 0.275 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.725 0.275 0.000
E50-E64 Other nutritional deficiencies
0.724 0.276 0.000
K65-K67 Diseases of peritoneum
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.723 0.277 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.722 0.278 0.000
G95.2 Cord compression, unspecified
0.722 0.278 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.719 0.281 0.000
I15 Secondary hypertension
0.719 0.281 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.719 0.281 0.000
V40-V49 Car occupant injured in transport accident
0.718 0.282 0.000
H18.4 Corneal degeneration
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
H50.0 Convergent concomitant strabismus
0.716 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F41 Other anxiety disorders
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.714 0.285 0.000
F30 Manic episode
0.714 0.285 0.000
F39 Unspecified mood [affective] disorder
0.714 0.285 0.000
E10.8 With unspecified complications
0.714 0.286 0.000
E10.7 With multiple complications
0.714 0.286 0.000
E10.6 With other specified complications
0.714 0.286 0.000
E10.0 With coma
0.714 0.286 0.000
M10 Gout
0.714 0.286 0.000
K07 Dentofacial anomalies [including malocclusion]
0.714 0.286 0.000
H35.3 Degeneration of macula and posterior pole
0.714 0.286 0.000
S32 Fracture of lumbar spine and pelvis
0.713 0.287 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.713 0.287 0.000
H31 Other disorders of choroid
0.713 0.287 0.000
H30 Chorioretinal inflammation
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.712 0.288 0.000
H49 Paralytic strabismus
0.712 0.288 0.000
F32.8 Other depressive episodes
0.711 0.289 0.000
E11.8 With unspecified complications
0.711 0.289 0.000
E11.7 With multiple complications
0.711 0.289 0.000
E11.6 With other specified complications
0.711 0.289 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
M94 Other disorders of cartilage
0.711 0.289 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.711 0.289 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.710 0.289 0.000
G60 Hereditary and idiopathic neuropathy
0.710 0.290 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.709 0.291 0.000
E67 Other hyperalimentation
0.708 0.291 0.000
E68 Sequelae of hyperalimentation
0.708 0.291 0.000
E65 Localised adiposity
0.708 0.291 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.708 0.292 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.708 0.292 0.000
S20-S29 Injuries to the thorax
0.708 0.292 0.000
I82 Other venous embolism and thrombosis
0.708 0.292 0.000
K72 Hepatic failure, not elsewhere classified
0.707 0.293 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.706 0.294 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.706 0.294 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.706 0.294 0.000
H17 Corneal scars and opacities
0.706 0.294 0.000
H15 Disorders of sclera
0.706 0.294 0.000
I52 Other heart disorders in diseases classified elsewhere
0.705 0.295 0.000
I48 Atrial fibrillation and flutter
0.705 0.295 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.705 0.295 0.000
I41 Myocarditis in diseases classified elsewhere
0.705 0.295 0.000
I40 Acute myocarditis
0.705 0.295 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.705 0.295 0.000
I37 Pulmonary valve disorders
0.705 0.295 0.000
I36 Nonrheumatic tricuspid valve disorders
0.705 0.295 0.000
I32 Pericarditis in diseases classified elsewhere
0.705 0.295 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.705 0.295 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.705 0.295 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.705 0.295 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.705 0.295 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.705 0.295 0.000
M77 Other enthesopathies
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.704 0.295 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.703 0.297 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.702 0.297 0.000
E66.1 Drug-induced obesity
0.702 0.297 0.000
E66.0 Obesity due to excess calories
0.702 0.297 0.000
S64 Injury of nerves at wrist and hand level
0.702 0.298 0.000
I74.5 Embolism and thrombosis of iliac artery
0.701 0.299 0.000
G93 Other disorders of brain
0.701 0.299 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.700 0.299 0.000
H55-H59 Other disorders of eye and adnexa
0.700 0.300 0.000
I45.1 Other and unspecified right bundle-branch block
0.700 0.300 0.000
V80-V89 Other land transport accidents
0.700 0.300 0.000
Y57 Other and unspecified drugs and medicaments
0.699 0.301 0.000
H52.0 Hypermetropia
0.699 0.301 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.697 0.302 0.000
H51 Other disorders of binocular movement
0.697 0.303 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.696 0.304 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.696 0.304 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.696 0.304 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
T36 Poisoning by systemic antibiotics
0.696 0.304 0.000
H50.9 Strabismus, unspecified
0.696 0.304 0.000
Chapter VIII Diseases of the ear and mastoid process
0.695 0.305 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.695 0.305 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.695 0.305 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.693 0.307 0.000
E16 Other disorders of pancreatic internal secretion
0.692 0.308 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.692 0.308 0.000
I72 Other aneurysm
0.692 0.308 0.000
H33.3 Retinal breaks without detachment
0.691 0.309 0.000
G91 Hydrocephalus
0.691 0.309 0.000
K92.8 Other specified diseases of digestive system
0.690 0.309 0.000
M60-M63 Disorders of muscles
0.690 0.310 0.000
K03 Other diseases of hard tissues of teeth
0.690 0.310 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.689 0.311 0.000
G95.9 Disease of spinal cord, unspecified
0.687 0.313 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.687 0.313 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.686 0.314 0.000
E10.5 With peripheral circulatory complications
0.685 0.315 0.000
K74.5 Biliary cirrhosis, unspecified
0.684 0.316 0.000
M65-M68 Disorders of synovium and tendon
0.684 0.316 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.684 0.316 0.000
F34.1 Dysthymia
0.684 0.316 0.000
F99-F99 Unspecified mental disorder
0.684 0.316 0.000
F41.2 Mixed anxiety and depressive disorder
0.684 0.316 0.000
Y35-Y36 Legal intervention and operations of war
0.683 0.317 0.000
Y10-Y34 Event of undetermined intent
0.683 0.317 0.000
X85-X99 Assault
0.683 0.317 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.683 0.317 0.000
X50-X57 Overexertion, travel and privation
0.683 0.317 0.000
X30-X39 Exposure to forces of nature
0.683 0.317 0.000
X20-X29 Contact with venomous animals and plants
0.683 0.317 0.000
X10-X19 Contact with heat and hot substances
0.683 0.317 0.000
X00-X09 Exposure to smoke, fire and flames
0.683 0.317 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.683 0.317 0.000
W75-W84 Other accidental threats to breathing
0.683 0.317 0.000
W65-W74 Accidental drowning and submersion
0.683 0.317 0.000
V98-V99 Other and unspecified transport accidents
0.683 0.317 0.000
V95-V97 Air and space transport accidents
0.683 0.317 0.000
V90-V94 Water transport accidents
0.683 0.317 0.000
V70-V79 Bus occupant injured in transport accident
0.683 0.317 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.683 0.317 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.683 0.317 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.683 0.317 0.000
V01-V09 Pedestrian injured in transport accident
0.683 0.317 0.000
T68 Hypothermia
0.682 0.318 0.000
V20-V29 Motorcycle rider injured in transport accident
0.682 0.318 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.681 0.318 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.681 0.319 0.000
I13 Hypertensive heart and renal disease
0.681 0.319 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.680 0.320 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.680 0.320 0.000
T39.4 Antirheumatics, not elsewhere classified
0.680 0.320 0.000
T39.2 Pyrazolone derivatives
0.680 0.320 0.000
K76.6 Portal hypertension
0.680 0.320 0.000
M00-M03 Infectious arthropathies
0.679 0.320 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
F32.0 Mild depressive episode
0.678 0.322 0.000
E14.3 With ophthalmic complications
0.678 0.322 0.000
J92.9 Pleural plaque without asbestos
0.678 0.322 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.676 0.323 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.676 0.324 0.000
M76 Enthesopathies of lower limb, excluding foot
0.676 0.324 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.676 0.324 0.000
K76.9 Liver disease, unspecified
0.676 0.324 0.000
K77 Liver disorders in diseases classified elsewhere
0.675 0.325 0.000
K71 Toxic liver disease
0.675 0.325 0.000
K70 Alcoholic liver disease
0.675 0.325 0.000
I51.6 Cardiovascular disease, unspecified
0.675 0.325 0.000
K09 Cysts of oral region, not elsewhere classified
0.675 0.325 0.000
Y40 Systemic antibiotics
0.674 0.326 0.000
K74.0 Hepatic fibrosis
0.672 0.328 0.000
J15.4 Pneumonia due to other streptococci
0.672 0.328 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.672 0.328 0.000
I77 Other disorders of arteries and arterioles
0.671 0.329 0.000
H35.7 Separation of retinal layers
0.671 0.329 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.670 0.330 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.670 0.330 0.000
G92 Toxic encephalopathy
0.670 0.330 0.000
K90.8 Other intestinal malabsorption
0.670 0.330 0.000
K90.3 Pancreatic steatorrhoea
0.670 0.330 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.670 0.330 0.000
K90.1 Tropical sprue
0.670 0.330 0.000
J10 Influenza due to identified influenza virus
0.670 0.330 0.000
K04.5 Chronic apical periodontitis
0.670 0.330 0.000
M75.8 Other shoulder lesions
0.669 0.331 0.000
M75.9 Shoulder lesion, unspecified
0.669 0.331 0.000
H52.2 Astigmatism
0.669 0.331 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.668 0.332 0.000
K76.8 Other specified diseases of liver
0.667 0.333 0.000
H47.2 Optic atrophy
0.667 0.333 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.666 0.334 0.000
S19 Other and unspecified injuries of neck
0.666 0.334 0.000
G72 Other myopathies
0.665 0.335 0.000
H20.0 Acute and subacute iridocyclitis
0.665 0.335 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.663 0.337 0.000
I74.8 Embolism and thrombosis of other arteries
0.663 0.337 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.663 0.337 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.663 0.337 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.663 0.337 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.663 0.337 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.662 0.338 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.660 0.340 0.000
M14 Arthropathies in other diseases classified elsewhere
0.660 0.340 0.000
M12 Other specific arthropathies
0.660 0.340 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.660 0.340 0.000
M08 Juvenile arthritis
0.660 0.340 0.000
G64 Other disorders of peripheral nervous system
0.660 0.340 0.000
S68 Traumatic amputation of wrist and hand
0.659 0.341 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.659 0.341 0.000
H35.4 Peripheral retinal degeneration
0.659 0.341 0.000
I88 Nonspecific lymphadenitis
0.658 0.342 0.000
M75.3 Calcific tendinitis of shoulder
0.658 0.342 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.657 0.343 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.657 0.343 0.000
H50.8 Other specified strabismus
0.657 0.343 0.000
H50.6 Mechanical strabismus
0.657 0.343 0.000
H50.4 Other and unspecified heterotropia
0.657 0.343 0.000
H50.3 Intermittent heterotropia
0.657 0.343 0.000
H50.2 Vertical strabismus
0.657 0.343 0.000
F31.8 Other bipolar affective disorders
0.655 0.345 0.000
F31.7 Bipolar affective disorder, currently in remission
0.655 0.345 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.655 0.345 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.655 0.345 0.000
G71 Primary disorders of muscles
0.655 0.345 0.000
I30 Acute pericarditis
0.655 0.345 0.000
S92.0 Fracture of calcaneus
0.654 0.346 0.000
I11 Hypertensive heart disease
0.653 0.347 0.000
M13.8 Other specified arthritis
0.652 0.348 0.000
M13.1 Monoarthritis, not elsewhere classified
0.652 0.348 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.651 0.349 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.651 0.349 0.000
H18.9 Disorder of cornea, unspecified
0.650 0.350 0.000
H18.8 Other specified disorders of cornea
0.650 0.350 0.000
H18.7 Other corneal deformities
0.650 0.350 0.000
H18.6 Keratoconus
0.650 0.350 0.000
H18.3 Changes in corneal membranes
0.650 0.350 0.000
H18.2 Other corneal oedema
0.650 0.350 0.000
H18.1 Bullous keratopathy
0.650 0.350 0.000
H18.0 Corneal pigmentations and deposits
0.650 0.350 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.650 0.350 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.650 0.350 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.649 0.351 0.000
H46 Optic neuritis
0.648 0.352 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.648 0.352 0.000
I85.0 Oesophageal varices with bleeding
0.648 0.352 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.647 0.353 0.000
I34 Nonrheumatic mitral valve disorders
0.647 0.353 0.000
F22 Persistent delusional disorders
0.646 0.354 0.000
H47.3 Other disorders of optic disk
0.646 0.354 0.000
G97.8 Other postprocedural disorders of nervous system
0.646 0.354 0.000
G62.8 Other specified polyneuropathies
0.644 0.356 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.644 0.356 0.000
Y44 Agents primarily affecting blood constituents
0.644 0.356 0.000
E20-E35 Disorders of other endocrine glands
0.644 0.356 0.000
S72.0 Fracture of neck of femur
0.642 0.358 0.000
S14 Injury of nerves and spinal cord at neck level
0.642 0.358 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.642 0.358 0.000
K00.6 Disturbances in tooth eruption
0.642 0.358 0.000
J11 Influenza, virus not identified
0.641 0.358 0.000
J93.8 Other pneumothorax
0.641 0.359 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.641 0.359 0.000
F25 Schizoaffective disorders
0.640 0.360 0.000
Y59 Other and unspecified vaccines and biological substances
0.639 0.360 0.000
Y58 Bacterial vaccines
0.639 0.360 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.639 0.360 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.639 0.360 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.639 0.360 0.000
Y48 Anaesthetics and therapeutic gases
0.639 0.360 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.639 0.360 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.639 0.360 0.000
M40-M43 Deforming dorsopathies
0.638 0.361 0.000
I51.5 Myocardial degeneration
0.638 0.362 0.000
I51.4 Myocarditis, unspecified
0.638 0.362 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.638 0.362 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.638 0.362 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.638 0.362 0.000
I51.0 Cardiac septal defect, acquired
0.638 0.362 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.638 0.362 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.636 0.364 0.000
K91.5 Postcholecystectomy syndrome
0.636 0.364 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.636 0.364 0.000
K91.1 Postgastric surgery syndromes
0.636 0.364 0.000
H34.2 Other retinal artery occlusions
0.636 0.364 0.000
I20 Angina pectoris
0.636 0.364 0.000
I86 Varicose veins of other sites
0.634 0.366 0.000
I81 Portal vein thrombosis
0.634 0.366 0.000
H16.0 Corneal ulcer
0.633 0.367 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.632 0.368 0.000
H35.5 Hereditary retinal dystrophy
0.632 0.368 0.000
H33.5 Other retinal detachments
0.631 0.369 0.000
T40.4 Other synthetic narcotics
0.630 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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