TreeWAS – Variant ID: rs77434118

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter VI Diseases of the nervous system	0.996	0.004
Chapter XI Diseases of the digestive system	0.995	0.005
Chapter II Neoplasms	0.995	0.005
K55-K64 Other diseases of intestines	0.991	0.009
C15-C26 Malignant neoplasms of digestive organs	0.990	0.010
S60-S69 Injuries to the wrist and hand	0.987	0.013
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.987	0.013
G50-G59 Nerve, nerve root and plexus disorders	0.987	0.013
K59 Other functional intestinal disorders	0.986	0.014
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.978	0.022
S50-S59 Injuries to the elbow and forearm	0.978	0.022
Chapter X Diseases of the respiratory system	0.976	0.024
M20-M25 Other joint disorders	0.976	0.024
J30-J39 Other diseases of upper respiratory tract	0.972	0.028
Chapter I Certain infectious and parasitic diseases	0.971	0.029
Chapter XX External causes of morbidity and mortality	0.964	0.036
M25 Other joint disorders, not elsewhere classified	0.960	0.040
K59.0 Constipation	0.960	0.040
K63 Other diseases of intestine	0.960	0.040
T85 Complications of other internal prosthetic devices, implants and grafts	0.958	0.042
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.956	0.044
K70-K77 Diseases of liver	0.946	0.054
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.946	0.054
K63.5 Polyp of colon	0.944	0.056
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.942	0.058
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.935	0.065
S40-S49 Injuries to the shoulder and upper arm	0.930	0.070
K59.8 Other specified functional intestinal disorders	0.929	0.071
M25.4 Effusion of joint	0.910	0.090
K76 Other diseases of liver	0.908	0.092
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.906	0.094
J00-J06 Acute upper respiratory infections	0.904	0.096
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.904	0.096
G90-G99 Other disorders of the nervous system	0.898	0.102
M80-M85 Disorders of bone density and structure	0.898	0.102
K63.9 Disease of intestine, unspecified	0.895	0.105
S52 Fracture of forearm	0.894	0.106
M23 Internal derangement of knee	0.894	0.106
K76.8 Other specified diseases of liver	0.893	0.107
Chapter VIII Diseases of the ear and mastoid process	0.888	0.112
G55.2 Nerve root and plexus compressions in spondylosis	0.886	0.114
J34 Other disorders of nose and nasal sinuses	0.885	0.115
C26 Malignant neoplasm of other and ill-defined digestive organs	0.882	0.118
W20-W49 Exposure to inanimate mechanical forces	0.879	0.121
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.879	0.121
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.876	0.124
A00-A09 Intestinal infectious diseases	0.875	0.125
M25.46 Effusion of joint (Lower leg)	0.874	0.126
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.870	0.130
K65-K67 Diseases of peritoneum	0.869	0.131
S80-S89 Injuries to the knee and lower leg	0.867	0.133
G58 Other mononeuropathies	0.867	0.133
G56 Mononeuropathies of upper limb	0.866	0.134
T85.4 Mechanical complication of breast prosthesis and implant	0.866	0.134
J34.3 Hypertrophy of nasal turbinates	0.864	0.136
G51 Facial nerve disorders	0.860	0.140
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.858	0.142
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.858	0.142
J32 Chronic sinusitis	0.856	0.144
C25 Malignant neoplasm of pancreas	0.855	0.145
K61 Abscess of anal and rectal regions	0.852	0.148
S51 Open wound of forearm	0.851	0.149
S62 Fracture at wrist and hand level	0.851	0.149
T93 Sequelae of injuries of lower limb	0.849	0.151
K90-K93 Other diseases of the digestive system	0.848	0.152
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.847	0.153
C23 Malignant neoplasm of gallbladder	0.845	0.155
D37-D48 Neoplasms of uncertain or unknown behaviour	0.844	0.156
Chapter XV Pregnancy, childbirth and the puerperium	0.844	0.156
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.844	0.156
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.842	0.158
K57 Diverticular disease of intestine	0.840	0.160
M25.5 Pain in joint	0.838	0.162
K10 Other diseases of jaws	0.835	0.165
S50 Superficial injury of forearm	0.835	0.165
S61 Open wound of wrist and hand	0.835	0.165
T90 Sequelae of injuries of head	0.834	0.166
M86-M90 Other osteopathies	0.834	0.166
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.833	0.167
J38.4 Oedema of larynx	0.832	0.168
G56.2 Lesion of ulnar nerve	0.830	0.170
S64 Injury of nerves at wrist and hand level	0.829	0.171
D00-D09 In situ neoplasms	0.825	0.175
M81 Osteoporosis without pathological fracture	0.824	0.176
W00-W19 Falls	0.821	0.179
B35-B49 Mycoses	0.820	0.180
S90-S99 Injuries to the ankle and foot	0.818	0.182
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.817	0.183
K57.3 Diverticular disease of large intestine without perforation or abscess	0.817	0.183
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.815	0.185
C83 Diffuse non-Hodgkin's lymphoma	0.813	0.187
C21 Malignant neoplasm of anus and anal canal	0.811	0.189
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.810	0.190
M25.56 Pain in joint (Lower leg)	0.809	0.191
D68 Other coagulation defects	0.808	0.192
S66 Injury of muscle and tendon at wrist and hand level	0.807	0.193
C26.0 Intestinal tract, part unspecified	0.804	0.196
M25.6 Stiffness of joint, not elsewhere classified	0.803	0.197
C18 Malignant neoplasm of colon	0.802	0.198
K65 Peritonitis	0.801	0.199
H65-H75 Diseases of middle ear and mastoid	0.800	0.200
W25 Contact with sharp glass	0.799	0.201
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.797	0.203
C16 Malignant neoplasm of stomach	0.796	0.203
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.794	0.206
K04 Diseases of pulp and periapical tissues	0.794	0.206
S52.6 Fracture of lower end of both ulna and radius	0.793	0.207
Chapter V Mental and behavioural disorders	0.793	0.207
G96 Other disorders of central nervous system	0.792	0.208
G90 Disorders of autonomic nervous system	0.791	0.209
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.791	0.209
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.791	0.209
M35 Other systemic involvement of connective tissue	0.790	0.210
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.789	0.211
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.789	0.211
S10-S19 Injuries to the neck	0.786	0.213
J06 Acute upper respiratory infections of multiple and unspecified sites	0.786	0.214
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.786	0.214
J39 Other diseases of upper respiratory tract	0.786	0.214
G60 Hereditary and idiopathic neuropathy	0.782	0.218
T92 Sequelae of injuries of upper limb	0.781	0.218
M60-M63 Disorders of muscles	0.781	0.219
G58.9 Mononeuropathy, unspecified	0.781	0.219
B90-B94 Sequelae of infectious and parasitic diseases	0.781	0.219
S68 Traumatic amputation of wrist and hand	0.780	0.220
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.778	0.222
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.778	0.222
M81.9 Osteoporosis, unspecified	0.777	0.223
B15-B19 Viral hepatitis	0.777	0.223
T66-T78 Other and unspecified effects of external causes	0.776	0.224
M23.2 Derangement of meniscus due to old tear or injury	0.774	0.226
K59.4 Anal spasm	0.774	0.226
K76.0 Fatty (change of) liver, not elsewhere classified	0.774	0.226
J30 Vasomotor and allergic rhinitis	0.773	0.227
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.773	0.227
T88 Other complications of surgical and medical care, not elsewhere classified	0.773	0.227
Chapter VII Diseases of the eye and adnexa	0.771	0.229
C78.7 Secondary malignant neoplasm of liver	0.770	0.230
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.770	0.230
G62 Other polyneuropathies	0.770	0.230
K14 Diseases of tongue	0.770	0.230
C19 Malignant neoplasm of rectosigmoid junction	0.769	0.231
T20-T25 Burns and corrosions of external body surface, specified by site	0.767	0.233
M24 Other specific joint derangements	0.766	0.234
A08 Viral and other specified intestinal infections	0.766	0.234
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.765	0.235
A04 Other bacterial intestinal infections	0.764	0.236
D80-D89 Certain disorders involving the immune mechanism	0.764	0.236
J60-J70 Lung diseases due to external agents	0.762	0.238
K11 Diseases of salivary glands	0.762	0.238
J32.9 Chronic sinusitis, unspecified	0.761	0.239
A15-A19 Tuberculosis	0.759	0.241
J09-J18 Influenza and pneumonia	0.758	0.242
J35 Chronic diseases of tonsils and adenoids	0.758	0.242
G63 Polyneuropathy in diseases classified elsewhere	0.758	0.242
G80-G83 Cerebral palsy and other paralytic syndromes	0.757	0.243
K72 Hepatic failure, not elsewhere classified	0.757	0.243
K10.8 Other specified diseases of jaws	0.757	0.243
A30-A49 Other bacterial diseases	0.756	0.244
G61 Inflammatory polyneuropathy	0.756	0.244
S56 Injury of muscle and tendon at forearm level	0.755	0.245
J36 Peritonsillar abscess	0.755	0.245
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.754	0.246
T15-T19 Effects of foreign body entering through natural orifice	0.753	0.246
M23.8 Other internal derangements of knee	0.753	0.247
G53 Cranial nerve disorders in diseases classified elsewhere	0.751	0.248
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.751	0.249
T80 Complications following infusion, transfusion and therapeutic injection	0.751	0.249
K55 Vascular disorders of intestine	0.750	0.250
C20 Malignant neoplasm of rectum	0.749	0.251
M21 Other acquired deformities of limbs	0.747	0.253
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.747	0.253
S70-S79 Injuries to the hip and thigh	0.747	0.253
J00 Acute nasopharyngitis [common cold]	0.747	0.253
C60-C63 Malignant neoplasms of male genital organs	0.746	0.254
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.746	0.254
K09 Cysts of oral region, not elsewhere classified	0.745	0.255
S46 Injury of muscle and tendon at shoulder and upper arm level	0.745	0.255
J03 Acute tonsillitis	0.743	0.257
W25.9 Unspecified place	0.742	0.258
T79-T79 Certain early complications of trauma	0.742	0.258
M25.9 Joint disorder, unspecified	0.741	0.259
B99-B99 Other infectious diseases	0.740	0.259
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.738	0.262
C15 Malignant neoplasm of oesophagus	0.737	0.263
K05 Gingivitis and periodontal diseases	0.737	0.263
S51.8 Open wound of other parts of forearm	0.736	0.264
M85 Other disorders of bone density and structure	0.736	0.264
O16 Unspecified maternal hypertension	0.736	0.264
C83.3 Large cell (diffuse)	0.734	0.266
C25.0 Head of pancreas	0.734	0.266
J37 Chronic laryngitis and laryngotracheitis	0.733	0.267
S50.9 Superficial injury of forearm, unspecified	0.733	0.267
D68.2 Hereditary deficiency of other clotting factors	0.731	0.269
W29 Contact with other powered hand tools and household machinery	0.730	0.270
K75 Other inflammatory liver diseases	0.729	0.271
T86 Failure and rejection of transplanted organs and tissues	0.728	0.272
X50-X57 Overexertion, travel and privation	0.728	0.272
S61.8 Open wound of other parts of wrist and hand	0.728	0.272
M25.8 Other specified joint disorders	0.728	0.272
T93.2 Sequelae of other fractures of lower limb	0.728	0.272
S69 Other and unspecified injuries of wrist and hand	0.727	0.273
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.724	0.276
K91.1 Postgastric surgery syndromes	0.724	0.276
S41 Open wound of shoulder and upper arm	0.723	0.277
M00-M03 Infectious arthropathies	0.723	0.277
M23.3 Other meniscus derangements	0.722	0.278
S67 Crushing injury of wrist and hand	0.721	0.278
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.721	0.278
G54 Nerve root and plexus disorders	0.721	0.279
T85.2 Mechanical complication of intraocular lens	0.721	0.279
S52.60 Fracture of lower end of both ulna and radius (closed)	0.721	0.279
Chapter XXII Codes for special purposes	0.721	0.279
S52.0 Fracture of upper end of ulna	0.721	0.279
M25.55 Pain in joint (Pelvic region and thigh)	0.720	0.280
K04.7 Periapical abscess without sinus	0.720	0.280
K61.0 Anal abscess	0.720	0.280
T87 Complications peculiar to reattachment and amputation	0.720	0.280
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.720	0.280
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.720	0.280
J38.1 Polyp of vocal cord and larynx	0.720	0.280
M45-M49 Spondylopathies	0.719	0.281
J38.7 Other diseases of larynx	0.719	0.281
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
O94-O99 Other obstetric conditions, not elsewhere classified	0.716	0.284
G51.0 Bell's palsy	0.716	0.284
K59.3 Megacolon, not elsewhere classified	0.716	0.284
Y60-Y69 Misadventures to patients during surgical and medical care	0.714	0.286
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
S89 Other and unspecified injuries of lower leg	0.713	0.287
X60-X84 Intentional self-harm	0.713	0.287
S42 Fracture of shoulder and upper arm	0.712	0.288
K07 Dentofacial anomalies [including malocclusion]	0.711	0.289
K64 Haemorrhoids and perianal venous thrombosis	0.711	0.289
S20-S29 Injuries to the thorax	0.710	0.290
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.710	0.290
C17 Malignant neoplasm of small intestine	0.710	0.290
K59.1 Functional diarrhoea	0.709	0.291
S65 Injury of blood vessels at wrist and hand level	0.708	0.292
G52 Disorders of other cranial nerves	0.708	0.292
K59.9 Functional intestinal disorder, unspecified	0.707	0.293
K59.2 Neurogenic bowel, not elsewhere classified	0.707	0.293
G51.8 Other disorders of facial nerve	0.707	0.293
S62.0 Fracture of navicular [scaphoid] bone of hand	0.706	0.293
M40-M43 Deforming dorsopathies	0.706	0.294
S30 Superficial injury of abdomen, lower back and pelvis	0.706	0.294
M65-M68 Disorders of synovium and tendon	0.705	0.295
B37 Candidiasis	0.703	0.297
X20-X29 Contact with venomous animals and plants	0.702	0.297
G59 Mononeuropathy in diseases classified elsewhere	0.702	0.298
J06.9 Acute upper respiratory infection, unspecified	0.701	0.299
S59 Other and unspecified injuries of forearm	0.701	0.299
S58 Traumatic amputation of forearm	0.701	0.299
S57 Crushing injury of forearm	0.701	0.299
S55 Injury of blood vessels at forearm level	0.701	0.299
S54 Injury of nerves at forearm level	0.701	0.299
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.701	0.299
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.701	0.299
K91.0 Vomiting following gastro-intestinal surgery	0.700	0.300
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.700	0.300
M33 Dermatopolymyositis	0.700	0.300
M32 Systemic lupus erythematosus	0.700	0.300
M30 Polyarteritis nodosa and related conditions	0.700	0.300
K06 Other disorders of gingiva and edentulous alveolar ridge	0.700	0.300
S81 Open wound of lower leg	0.698	0.302
M91-M94 Chondropathies	0.698	0.302
S40 Superficial injury of shoulder and upper arm	0.696	0.304
G90.0 Idiopathic peripheral autonomic neuropathy	0.696	0.304
B85-B89 Pediculosis, acariasis and other infestations	0.696	0.304
B65-B83 Helminthiases	0.696	0.304
B50-B64 Protozoal diseases	0.696	0.304
B20-B24 Human immunodeficiency virus [HIV] disease	0.696	0.304
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.696	0.304
A75-A79 Rickettsioses	0.696	0.304
A70-A74 Other diseases caused by chlamydiae	0.696	0.304
A65-A69 Other spirochaetal diseases	0.696	0.304
A20-A28 Certain zoonotic bacterial diseases	0.696	0.304
J01 Acute sinusitis	0.695	0.305
M81.99 Osteoporosis, unspecified (Site unspecified)	0.695	0.305
S63.6 Sprain and strain of finger(s)	0.695	0.305
G95 Other diseases of spinal cord	0.694	0.306
A40 Streptococcal septicaemia	0.694	0.306
H74 Other disorders of middle ear and mastoid	0.693	0.307
S49 Other and unspecified injuries of shoulder and upper arm	0.693	0.307
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.692	0.308
C71 Malignant neoplasm of brain	0.692	0.308
S43.0 Dislocation of shoulder joint	0.692	0.308
T90.5 Sequelae of intracranial injury	0.691	0.309
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.691	0.309
Y35-Y36 Legal intervention and operations of war	0.691	0.309
Y10-Y34 Event of undetermined intent	0.691	0.309
Y00-Y09 Assault	0.691	0.309
X85-X99 Assault	0.691	0.309
X58-X59 Accidental exposure to other and unspecified factors	0.691	0.309
X40-X49 Accidental poisoning by and exposure to noxious substances	0.691	0.309
X30-X39 Exposure to forces of nature	0.691	0.309
X10-X19 Contact with heat and hot substances	0.691	0.309
X00-X09 Exposure to smoke, fire and flames	0.691	0.309
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.691	0.309
W75-W84 Other accidental threats to breathing	0.691	0.309
W65-W74 Accidental drowning and submersion	0.691	0.309
W50-W64 Exposure to animate mechanical forces	0.691	0.309
V98-V99 Other and unspecified transport accidents	0.691	0.309
V95-V97 Air and space transport accidents	0.691	0.309
V90-V94 Water transport accidents	0.691	0.309
V80-V89 Other land transport accidents	0.691	0.309
V70-V79 Bus occupant injured in transport accident	0.691	0.309
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.691	0.309
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.691	0.309
V40-V49 Car occupant injured in transport accident	0.691	0.309
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.691	0.309
V01-V09 Pedestrian injured in transport accident	0.691	0.309
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.691	0.309
M34 Systemic sclerosis	0.689	0.311
S51.9 Open wound of forearm, part unspecified	0.689	0.311
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.689	0.311
M25.3 Other instability of joint	0.688	0.312
M25.2 Flail joint	0.688	0.312
M25.1 Fistula of joint	0.688	0.312
M25.0 Haemarthrosis	0.688	0.312
K63.4 Enteroptosis	0.688	0.312
K63.0 Abscess of intestine	0.688	0.312
A08.4 Viral intestinal infection, unspecified	0.688	0.312
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.687	0.313
K14.0 Glossitis	0.687	0.313
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.687	0.313
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.687	0.313
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.687	0.313
V20-V29 Motorcycle rider injured in transport accident	0.687	0.313
G00-G09 Inflammatory diseases of the central nervous system	0.686	0.314
S52.1 Fracture of upper end of radius	0.686	0.314
Chapter IV Endocrine, nutritional and metabolic diseases	0.686	0.314
S60 Superficial injury of wrist and hand	0.686	0.314
T98 Sequelae of other and unspecified effects of external causes	0.686	0.314
T95 Sequelae of burns, corrosions and frostbite	0.686	0.314
T94 Sequelae of injuries involving multiple and unspecified body regions	0.686	0.314
T91 Sequelae of injuries of neck and trunk	0.686	0.314
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.686	0.314
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.686	0.314
S36 Injury of intra-abdominal organs	0.685	0.315
Y42.5 Other oestrogens and progestogens	0.685	0.315
M81.90 Osteoporosis, unspecified (Multiple sites)	0.685	0.315
M31 Other necrotising vasculopathies	0.685	0.315
G91 Hydrocephalus	0.684	0.316
W07 Fall involving chair	0.683	0.316
M35.3 Polymyalgia rheumatica	0.683	0.317
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.681	0.319
H60-H62 Diseases of external ear	0.681	0.319
H30-H36 Disorders of choroid and retina	0.680	0.320
S64.3 Injury of digital nerve of thumb	0.680	0.320
G20-G26 Extrapyramidal and movement disorders	0.680	0.320
S32 Fracture of lumbar spine and pelvis	0.680	0.320
D60-D64 Aplastic and other anaemias	0.679	0.321
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.679	0.321
C21.1 Anal canal	0.679	0.321
H46-H48 Disorders of optic nerve and visual pathways	0.678	0.322
K77 Liver disorders in diseases classified elsewhere	0.678	0.322
K73 Chronic hepatitis, not elsewhere classified	0.678	0.322
K71 Toxic liver disease	0.678	0.322
J39.2 Other diseases of pharynx	0.678	0.322
K03 Other diseases of hard tissues of teeth	0.678	0.322
S91 Open wound of ankle and foot	0.677	0.323
S61.7 Multiple open wounds of wrist and hand	0.677	0.323
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.677	0.323
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.675	0.324
G55.0 Nerve root and plexus compressions in neoplastic disease	0.675	0.324
S52.8 Fracture of other parts of forearm	0.675	0.324
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.675	0.325
A80-A89 Viral infections of the central nervous system	0.675	0.325
O80-O84 Delivery	0.675	0.325
K65.0 Acute peritonitis	0.675	0.325
G70-G73 Diseases of myoneural junction and muscle	0.674	0.326
D04 Carcinoma in situ of skin	0.674	0.326
G60.0 Hereditary motor and sensory neuropathy	0.673	0.327
K00 Disorders of tooth development and eruption	0.671	0.329
G62.9 Polyneuropathy, unspecified	0.671	0.329
S86 Injury of muscle and tendon at lower leg level	0.671	0.329
G64 Other disorders of peripheral nervous system	0.670	0.329
S64.0 Injury of ulnar nerve at wrist and hand level	0.670	0.330
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.669	0.330
B07 Viral warts	0.670	0.330
J38.2 Nodules of vocal cords	0.669	0.331
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.669	0.331
E65-E68 Obesity and other hyperalimentation	0.669	0.331
K61.3 Ischiorectal abscess	0.668	0.331
K02 Dental caries	0.668	0.331
C18.0 Caecum	0.668	0.332
W44 Foreign body entering into or through eye or natural orifice	0.667	0.333
K65.9 Peritonitis, unspecified	0.667	0.333
S48 Traumatic amputation of shoulder and upper arm	0.666	0.333
S45 Injury of blood vessels at shoulder and upper arm level	0.666	0.333
S44 Injury of nerves at shoulder and upper arm level	0.666	0.333
S47 Crushing injury of shoulder and upper arm	0.666	0.333
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.666	0.333
K72.0 Acute and subacute hepatic failure	0.666	0.334
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.666	0.334
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.665	0.335
O00-O08 Pregnancy with abortive outcome	0.665	0.335
M90 Osteopathies in diseases classified elsewhere	0.664	0.336
D03 Melanoma in situ	0.664	0.336
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.663	0.337
S62.2 Fracture of first metacarpal bone	0.663	0.337
G96.0 Cerebrospinal fluid leak	0.662	0.338
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.662	0.338
F40-F48 Neurotic, stress-related and somatoform disorders	0.661	0.339
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.661	0.339
G96.1 Disorders of meninges, not elsewhere classified	0.661	0.339
C25.9 Pancreas, unspecified	0.661	0.339
A50-A64 Infections with a predominantly sexual mode of transmission	0.661	0.339
J32.0 Chronic maxillary sinusitis	0.661	0.339
S82 Fracture of lower leg, including ankle	0.660	0.340
M25.47 Effusion of joint (Ankle and foot)	0.659	0.341
S61.1 Open wound of finger(s) with damage to nail	0.659	0.341
Y57 Other and unspecified drugs and medicaments	0.657	0.343
C18.6 Descending colon	0.657	0.343
E66 Obesity	0.657	0.343
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.656	0.343
D68.5 Primary Thrombophilia	0.656	0.344
H71 Cholesteatoma of middle ear	0.655	0.345
D68.8 Other specified coagulation defects	0.655	0.345
K65.8 Other peritonitis	0.654	0.346
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.653	0.347
M25.49 Effusion of joint (Site unspecified)	0.652	0.347
M25.48 Effusion of joint (Other)	0.652	0.347
M25.45 Effusion of joint (Pelvic region and thigh)	0.652	0.347
M25.44 Effusion of joint (Hand)	0.652	0.347
M25.43 Effusion of joint (Forearm)	0.652	0.347
M25.42 Effusion of joint (Upper arm)	0.652	0.347
M25.41 Effusion of joint (Shoulder region)	0.652	0.347
M25.40 Effusion of joint (Multiple sites)	0.652	0.347
J31.0 Chronic rhinitis	0.652	0.348
T90.9 Sequelae of unspecified injury of head	0.651	0.349
K76.7 Hepatorenal syndrome	0.651	0.349
K76.5 Hepatic veno-occlusive disease	0.651	0.349
K76.4 Peliosis hepatis	0.651	0.349
K76.3 Infarction of liver	0.651	0.349
K76.2 Central haemorrhagic necrosis of liver	0.651	0.349
K76.1 Chronic passive congestion of liver	0.651	0.349
T93.8 Sequelae of other specified injuries of lower limb	0.651	0.349
E66.9 Obesity, unspecified	0.651	0.349
J38.6 Stenosis of larynx	0.649	0.350
J38.5 Laryngeal spasm	0.649	0.350
M87 Osteonecrosis	0.649	0.351
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.649	0.351
T51 Toxic effect of alcohol	0.649	0.351
C18.1 Appendix	0.649	0.351
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.648	0.352
D55-D59 Haemolytic anaemias	0.648	0.352
T90.2 Sequelae of fracture of skull and facial bones	0.648	0.352
S62.5 Fracture of thumb	0.648	0.352
G82 Paraplegia and tetraplegia	0.647	0.352
F60-F69 Disorders of adult personality and behaviour	0.647	0.353
C78.1 Secondary malignant neoplasm of mediastinum	0.646	0.354
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.646	0.354
Q20-Q28 Congenital malformations of the circulatory system	0.645	0.355
M86 Osteomyelitis	0.645	0.355
J80-J84 Other respiratory diseases principally affecting the interstitium	0.645	0.355
B91 Sequelae of poliomyelitis	0.644	0.355
M23.30 Other meniscus derangements (Multiple sites)	0.644	0.356
C73 Malignant neoplasm of thyroid gland	0.644	0.356
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.644	0.356
G94 Other disorders of brain in diseases classified elsewhere	0.644	0.356
G98 Other disorders of nervous system, not elsewhere classified	0.644	0.356
G92 Toxic encephalopathy	0.644	0.356
D02 Carcinoma in situ of middle ear and respiratory system	0.644	0.356
M83 Adult osteomalacia	0.644	0.356
M82 Osteoporosis in diseases classified elsewhere	0.644	0.356
C92 Myeloid leukaemia	0.643	0.357
K13 Other diseases of lip and oral mucosa	0.643	0.357
J04 Acute laryngitis and tracheitis	0.641	0.359
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.641	0.359
S52.9 Fracture of forearm, part unspecified	0.641	0.359
S52.7 Multiple fractures of forearm	0.641	0.359
S52.4 Fracture of shafts of both ulna and radius	0.641	0.359
S52.3 Fracture of shaft of radius	0.641	0.359
S52.2 Fracture of shaft of ulna	0.641	0.359
J38.3 Other diseases of vocal cords	0.641	0.359
M23.9 Internal derangement of knee, unspecified	0.641	0.359
M23.6 Other spontaneous disruption of ligament(s) of knee	0.641	0.359
M23.5 Chronic instability of knee	0.641	0.359
M23.1 Discoid meniscus (congenital)	0.641	0.359
M23.0 Cystic meniscus	0.641	0.359
S62.3 Fracture of other metacarpal bone	0.640	0.360
H90-H95 Other disorders of ear	0.640	0.360
D46 Myelodysplastic syndromes	0.640	0.360
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.640	0.360
M70-M79 Other soft tissue disorders	0.640	0.360
C16.0 Cardia	0.638	0.361
K04.6 Periapical abscess with sinus	0.636	0.364
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.636	0.364
O85-O92 Complications predominantly related to the puerperium	0.635	0.365
S90 Superficial injury of ankle and foot	0.635	0.365
D89.2 Hypergammaglobulinaemia, unspecified	0.635	0.365
J34.1 Cyst and mucocele of nose and nasal sinus	0.635	0.365
J34.0 Abscess, furuncle and carbuncle of nose	0.635	0.365

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations