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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77556290
log Bayes Factor = 6.95852
Chromosome 4   position 105,880,750  (GRCh37) Explore rs77556290 on Ensembl!
Variant rs77556290 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
N92 Excessive, frequent and irregular menstruation
0.994 0.006 0.000
Chapter XXI Factors influencing health status and contact with health services
0.992 0.008 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.979 0.021 0.000
N95 Menopausal and other perimenopausal disorders
0.976 0.024 0.000
N81 Female genital prolapse
0.971 0.029 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.968 0.032 0.000
Chapter XX External causes of morbidity and mortality
0.965 0.035 0.000
N95.0 Postmenopausal bleeding
0.958 0.042 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.952 0.048 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.949 0.051 0.000
N30-N39 Other diseases of urinary system
0.946 0.054 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.931 0.069 0.000
Z96 Presence of other functional implants
0.927 0.073 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.924 0.076 0.000
N92.6 Irregular menstruation, unspecified
0.922 0.078 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.915 0.085 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.910 0.090 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.903 0.097 0.000
N32 Other disorders of bladder
0.903 0.097 0.000
Z96.1 Presence of intraocular lens
0.895 0.105 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.894 0.106 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.882 0.118 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.882 0.118 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.882 0.118 0.000
N92.3 Ovulation bleeding
0.877 0.123 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.876 0.124 0.000
N81.6 Rectocele
0.869 0.131 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.865 0.135 0.000
Chapter VII Diseases of the eye and adnexa
0.864 0.136 0.000
Z93 Artificial opening status
0.860 0.140 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.859 0.141 0.000
N88 Other noninflammatory disorders of cervix uteri
0.855 0.145 0.000
Y83.6 Removal of other organ (partial) (total)
0.853 0.147 0.000
N85.2 Hypertrophy of uterus
0.849 0.151 0.000
S00-S09 Injuries to the head
0.848 0.151 0.000
N32.8 Other specified disorders of bladder
0.847 0.153 0.000
S60-S69 Injuries to the wrist and hand
0.847 0.153 0.000
O60-O75 Complications of labour and delivery
0.846 0.154 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.845 0.155 0.000
O00-O08 Pregnancy with abortive outcome
0.844 0.156 0.000
Chapter II Neoplasms
0.838 0.162 0.000
Z90.7 Acquired absence of genital organ(s)
0.835 0.165 0.000
S20-S29 Injuries to the thorax
0.834 0.166 0.000
Chapter I Certain infectious and parasitic diseases
0.833 0.167 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.828 0.172 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.816 0.184 0.000
Z96.0 Presence of urogenital implants
0.815 0.185 0.000
Chapter VI Diseases of the nervous system
0.815 0.185 0.000
T81 Complications of procedures, not elsewhere classified
0.813 0.187 0.000
N81.2 Incomplete uterovaginal prolapse
0.800 0.200 0.000
N00-N08 Glomerular diseases
0.794 0.206 0.000
Z98 Other postsurgical states
0.793 0.207 0.000
O36 Maternal care for other known or suspected foetal problems
0.792 0.208 0.000
Chapter VIII Diseases of the ear and mastoid process
0.790 0.210 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.790 0.210 0.000
N81.1 Cystocele
0.789 0.211 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.785 0.215 0.000
N89 Other noninflammatory disorders of vagina
0.783 0.217 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.782 0.218 0.000
Z93.2 Ileostomy status
0.781 0.219 0.000
N32.9 Bladder disorder, unspecified
0.781 0.219 0.000
W20-W49 Exposure to inanimate mechanical forces
0.780 0.220 0.000
Z85 Personal history of malignant neoplasm
0.775 0.225 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.775 0.225 0.000
E65-E68 Obesity and other hyperalimentation
0.774 0.226 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.773 0.227 0.000
S80-S89 Injuries to the knee and lower leg
0.771 0.228 0.000
N81.5 Vaginal enterocele
0.771 0.229 0.000
D60-D64 Aplastic and other anaemias
0.771 0.229 0.000
N86 Erosion and ectropion of cervix uteri
0.770 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.769 0.231 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.769 0.231 0.000
S40-S49 Injuries to the shoulder and upper arm
0.767 0.233 0.000
Chapter XI Diseases of the digestive system
0.766 0.234 0.000
N81.4 Uterovaginal prolapse, unspecified
0.765 0.235 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.765 0.235 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.763 0.237 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.762 0.238 0.000
H04 Disorders of lachrymal system
0.761 0.239 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.759 0.241 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.757 0.243 0.000
N99-N99 Other disorders of the genitourinary system
0.757 0.243 0.000
N85.4 Malposition of uterus
0.752 0.248 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.750 0.250 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.746 0.254 0.000
O80-O84 Delivery
0.745 0.255 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.744 0.256 0.000
S01 Open wound of head
0.739 0.261 0.000
O42 Premature rupture of membranes
0.739 0.261 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.738 0.262 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.738 0.262 0.000
Y83.3 Surgical operation with formation of external stoma
0.738 0.262 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.736 0.264 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.734 0.266 0.000
Z94 Transplanted organ and tissue status
0.733 0.266 0.000
Z37 Outcome of delivery
0.732 0.268 0.000
N81.8 Other female genital prolapse
0.730 0.270 0.000
Z96.8 Presence of other specified functional implants
0.728 0.272 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.727 0.273 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.726 0.274 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.725 0.275 0.000
Z90.2 Acquired absence of lung [part of]
0.722 0.278 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.721 0.279 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.721 0.279 0.000
O02 Other abnormal products of conception
0.721 0.279 0.000
Z91.5 Personal history of self-harm
0.720 0.280 0.000
N94.1 Dyspareunia
0.720 0.280 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.718 0.282 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.717 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.715 0.285 0.000
S61 Open wound of wrist and hand
0.715 0.285 0.000
N35 Urethral stricture
0.714 0.286 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
T66-T78 Other and unspecified effects of external causes
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
O47 False labour
0.714 0.286 0.000
N92.5 Other specified irregular menstruation
0.713 0.287 0.000
N92.4 Excessive bleeding in the premenopausal period
0.713 0.287 0.000
N92.2 Excessive menstruation at puberty
0.713 0.287 0.000
Z90.1 Acquired absence of breast(s)
0.712 0.288 0.000
Z04 Examination and observation for other reasons
0.710 0.290 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.708 0.292 0.000
Z90.5 Acquired absence of kidney
0.707 0.293 0.000
N87 Dysplasia of cervix uteri
0.706 0.294 0.000
N95.2 Postmenopausal atrophic vaginitis
0.706 0.294 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.704 0.296 0.000
A00-A09 Intestinal infectious diseases
0.703 0.297 0.000
C15-C26 Malignant neoplasms of digestive organs
0.702 0.298 0.000
O85-O92 Complications predominantly related to the puerperium
0.702 0.298 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.702 0.298 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.701 0.299 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.701 0.299 0.000
N39 Other disorders of urinary system
0.700 0.300 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.700 0.300 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.700 0.300 0.000
N95.3 States associated with artificial menopause
0.700 0.300 0.000
N95.1 Menopausal and female climacteric states
0.700 0.300 0.000
Z80 Family history of malignant neoplasm
0.699 0.301 0.000
S50-S59 Injuries to the elbow and forearm
0.698 0.302 0.000
O48 Prolonged pregnancy
0.697 0.303 0.000
N81.9 Female genital prolapse, unspecified
0.696 0.303 0.000
N81.3 Complete uterovaginal prolapse
0.696 0.303 0.000
N81.0 Female urethrocele
0.696 0.303 0.000
O70 Perineal laceration during delivery
0.695 0.305 0.000
D69 Purpura and other haemorrhagic conditions
0.695 0.305 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.694 0.306 0.000
Z97 Presence of other devices
0.694 0.306 0.000
Z89 Acquired absence of limb
0.694 0.306 0.000
Z84 Family history of other conditions
0.694 0.306 0.000
Z81 Family history of mental and behavioural disorders
0.694 0.306 0.000
N97 Female infertility
0.694 0.306 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
Y35-Y36 Legal intervention and operations of war
0.692 0.308 0.000
Y10-Y34 Event of undetermined intent
0.692 0.308 0.000
Y00-Y09 Assault
0.692 0.308 0.000
X85-X99 Assault
0.692 0.308 0.000
X60-X84 Intentional self-harm
0.692 0.308 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.692 0.308 0.000
X50-X57 Overexertion, travel and privation
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.692 0.308 0.000
X30-X39 Exposure to forces of nature
0.692 0.308 0.000
X20-X29 Contact with venomous animals and plants
0.692 0.308 0.000
X10-X19 Contact with heat and hot substances
0.692 0.308 0.000
X00-X09 Exposure to smoke, fire and flames
0.692 0.308 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.692 0.308 0.000
W75-W84 Other accidental threats to breathing
0.692 0.308 0.000
W65-W74 Accidental drowning and submersion
0.692 0.308 0.000
W50-W64 Exposure to animate mechanical forces
0.692 0.308 0.000
V98-V99 Other and unspecified transport accidents
0.692 0.308 0.000
V95-V97 Air and space transport accidents
0.692 0.308 0.000
V90-V94 Water transport accidents
0.692 0.308 0.000
V80-V89 Other land transport accidents
0.692 0.308 0.000
V70-V79 Bus occupant injured in transport accident
0.692 0.308 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.692 0.308 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.692 0.308 0.000
V40-V49 Car occupant injured in transport accident
0.692 0.308 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.692 0.308 0.000
V20-V29 Motorcycle rider injured in transport accident
0.692 0.308 0.000
V10-V19 Pedal cyclist injured in transport accident
0.692 0.308 0.000
V01-V09 Pedestrian injured in transport accident
0.692 0.308 0.000
E00-E07 Disorders of thyroid gland
0.690 0.310 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.689 0.311 0.000
E70-E90 Metabolic disorders
0.688 0.312 0.000
B95-B98 Bacterial, viral and other infectious agents
0.688 0.312 0.000
E66 Obesity
0.688 0.312 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.687 0.313 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.685 0.315 0.000
Y83.9 Surgical procedure, unspecified
0.685 0.315 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.682 0.318 0.000
Z10 Routine general health check-up of defined subpopulation
0.682 0.318 0.000
Z83 Family history of other specific disorders
0.682 0.318 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.681 0.319 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.680 0.320 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.680 0.320 0.000
N85.7 Haematometra
0.680 0.320 0.000
N85.6 Intra-uterine synechiae
0.680 0.320 0.000
N85.5 Inversion of uterus
0.680 0.320 0.000
N85.3 Subinvolution of uterus
0.680 0.320 0.000
N85.1 Endometrial adenomatous hyperplasia
0.680 0.320 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.680 0.320 0.000
N37 Urethral disorders in diseases classified elsewhere
0.678 0.322 0.000
N36 Other disorders of urethra
0.678 0.322 0.000
N34 Urethritis and urethral syndrome
0.678 0.322 0.000
N33 Bladder disorders in diseases classified elsewhere
0.678 0.322 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.677 0.323 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.674 0.325 0.000
E20-E35 Disorders of other endocrine glands
0.674 0.326 0.000
G56 Mononeuropathies of upper limb
0.673 0.327 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.673 0.327 0.000
Z37.0 Single live birth
0.672 0.328 0.000
H40-H42 Glaucoma
0.671 0.329 0.000
K90-K93 Other diseases of the digestive system
0.671 0.329 0.000
H30-H36 Disorders of choroid and retina
0.670 0.330 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.670 0.330 0.000
K70-K77 Diseases of liver
0.670 0.330 0.000
O36.8 Maternal care for other specified foetal problems
0.668 0.331 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.668 0.332 0.000
T87 Complications peculiar to reattachment and amputation
0.668 0.332 0.000
T86 Failure and rejection of transplanted organs and tissues
0.668 0.332 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.668 0.332 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.668 0.332 0.000
W00-W19 Falls
0.667 0.333 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.667 0.333 0.000
N80 Endometriosis
0.666 0.334 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.665 0.335 0.000
Z96.9 Presence of functional implant, unspecified
0.664 0.335 0.000
Z96.7 Presence of other bone and tendon implants
0.664 0.335 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.664 0.335 0.000
Z96.4 Presence of endocrine implants
0.664 0.335 0.000
Z96.3 Presence of artificial larynx
0.664 0.335 0.000
Z96.2 Presence of otological and audiological implants
0.664 0.335 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.664 0.336 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.662 0.338 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.662 0.338 0.000
Chapter V Mental and behavioural disorders
0.661 0.339 0.000
N10-N16 Renal tubulo-interstitial diseases
0.660 0.339 0.000
O03 Spontaneous abortion
0.660 0.340 0.000
K40-K46 Hernia
0.659 0.341 0.000
D64 Other anaemias
0.658 0.341 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.658 0.342 0.000
N25-N29 Other disorders of kidney and ureter
0.657 0.343 0.000
O45 Premature separation of placenta [abruptio placentae]
0.656 0.344 0.000
O44 Placenta praevia
0.656 0.344 0.000
O43 Placental disorders
0.656 0.344 0.000
O41 Other disorders of amniotic fluid and membranes
0.656 0.344 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.656 0.344 0.000
O33 Maternal care for known or suspected disproportion
0.656 0.344 0.000
O31 Complications specific to multiple gestation
0.656 0.344 0.000
O30 Multiple gestation
0.656 0.344 0.000
O40 Polyhydramnios
0.656 0.344 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.655 0.345 0.000
D00-D09 In situ neoplasms
0.655 0.345 0.000
O63 Long labour
0.654 0.346 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.652 0.348 0.000
C51-C58 Malignant neoplasms of female genital organs
0.651 0.349 0.000
N85.0 Endometrial glandular hyperplasia
0.650 0.350 0.000
Z12 Special screening examination for neoplasms
0.650 0.350 0.000
Z98.0 Intestinal bypass and anastomosis status
0.649 0.351 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.648 0.352 0.000
W25 Contact with sharp glass
0.648 0.352 0.000
Z90.8 Acquired absence of other organs
0.647 0.352 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.647 0.352 0.000
Z90.3 Acquired absence of part of stomach
0.647 0.352 0.000
Z90.0 Acquired absence of part of head and neck
0.647 0.352 0.000
N32.4 Rupture of bladder, nontraumatic
0.647 0.353 0.000
N32.2 Vesical fistula, not elsewhere classified
0.647 0.353 0.000
N32.1 Vesicointestinal fistula
0.647 0.353 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.646 0.353 0.000
E50-E64 Other nutritional deficiencies
0.646 0.354 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.645 0.355 0.000
S01.8 Open wound of other parts of head
0.644 0.356 0.000
N60-N64 Disorders of breast
0.644 0.356 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.643 0.357 0.000
G20-G26 Extrapyramidal and movement disorders
0.643 0.357 0.000
G56.0 Carpal tunnel syndrome
0.642 0.358 0.000
E40-E46 Malnutrition
0.641 0.359 0.000
H90-H95 Other disorders of ear
0.640 0.360 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.639 0.361 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.639 0.361 0.000
N88.2 Stricture and stenosis of cervix uteri
0.638 0.362 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.637 0.363 0.000
S00 Superficial injury of head
0.636 0.363 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.636 0.364 0.000
A04 Other bacterial intestinal infections
0.636 0.364 0.000
B35-B49 Mycoses
0.635 0.365 0.000
N32.3 Diverticulum of bladder
0.635 0.365 0.000
N30 Cystitis
0.634 0.366 0.000
Y40 Systemic antibiotics
0.633 0.367 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.633 0.367 0.000
N94.5 Secondary dysmenorrhoea
0.633 0.367 0.000
N94.4 Primary dysmenorrhoea
0.633 0.367 0.000
N94.3 Premenstrual tension syndrome
0.633 0.367 0.000
N94.2 Vaginismus
0.633 0.367 0.000
N94.0 Mittelschmerz
0.633 0.367 0.000
D80-D89 Certain disorders involving the immune mechanism
0.633 0.367 0.000
D55-D59 Haemolytic anaemias
0.633 0.367 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.632 0.367 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.632 0.367 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.632 0.367 0.000
O02.1 Missed abortion
0.632 0.368 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.632 0.368 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.631 0.369 0.000
N73 Other female pelvic inflammatory diseases
0.631 0.369 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.630 0.370 0.000
S32 Fracture of lumbar spine and pelvis
0.629 0.370 0.000
Z01.8 Other specified special examinations
0.628 0.372 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.628 0.372 0.000
Y83.5 Amputation of limb(s)
0.628 0.372 0.000
Y83.4 Other reconstructive surgery
0.628 0.372 0.000
Y83.0 Surgical operation with transplant of whole organ
0.628 0.372 0.000
N93 Other abnormal uterine and vaginal bleeding
0.628 0.372 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.627 0.372 0.000
S62 Fracture at wrist and hand level
0.625 0.374 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.625 0.375 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.625 0.375 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.624 0.375 0.000
E66.9 Obesity, unspecified
0.624 0.376 0.000
Z93.3 Colostomy status
0.623 0.377 0.000
S02 Fracture of skull and facial bones
0.623 0.377 0.000
Y84.0 Cardiac catheterisation
0.622 0.378 0.000
G30-G32 Other degenerative diseases of the nervous system
0.621 0.378 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.620 0.380 0.000
Z91.7 Personal history of female genital mutilation
0.620 0.380 0.000
Z91.6 Personal history of other physical trauma
0.620 0.380 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.620 0.380 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.620 0.380 0.000
Z91.2 Personal history of poor personal hygiene
0.620 0.380 0.000
H55-H59 Other disorders of eye and adnexa
0.619 0.380 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.619 0.380 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.619 0.380 0.000
H10-H13 Disorders of conjunctiva
0.619 0.380 0.000
Z36 Antenatal screening
0.618 0.381 0.000
N32.0 Bladder-neck obstruction
0.617 0.383 0.000
Z93.9 Artificial opening status, unspecified
0.617 0.383 0.000
Z93.8 Other artificial opening status
0.617 0.383 0.000
Z93.6 Other artificial openings of urinary tract status
0.617 0.383 0.000
Z93.5 Cystostomy status
0.617 0.383 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.617 0.383 0.000
Z93.1 Gastrostomy status
0.617 0.383 0.000
Z93.0 Tracheostomy status
0.617 0.383 0.000
Z02 Examination and encounter for administrative purposes
0.616 0.384 0.000
K90 Intestinal malabsorption
0.615 0.385 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.615 0.385 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.614 0.386 0.000
S22.4 Multiple fractures of ribs
0.614 0.386 0.000
N03 Chronic nephritic syndrome
0.614 0.386 0.000
K44 Diaphragmatic hernia
0.614 0.386 0.000
N39.3 Stress incontinence
0.614 0.386 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.613 0.387 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.613 0.387 0.000
N88.3 Incompetence of cervix uteri
0.613 0.387 0.000
N88.1 Old laceration of cervix uteri
0.613 0.387 0.000
N88.0 Leukoplakia of cervix uteri
0.613 0.387 0.000
O42.9 Premature rupture of membranes, unspecified
0.612 0.388 0.000
H43-H45 Disorders of vitreous body and globe
0.612 0.388 0.000
H53-H54 Visual disturbances and blindness
0.611 0.389 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.611 0.389 0.000
S82 Fracture of lower leg, including ankle
0.611 0.389 0.000
Z13 Special screening examination for other diseases and disorders
0.610 0.389 0.000
N02 Recurrent and persistent haematuria
0.609 0.391 0.000
S08 Traumatic amputation of part of head
0.608 0.392 0.000
S07 Crushing injury of head
0.608 0.392 0.000
S06 Intracranial injury
0.608 0.392 0.000
S05 Injury of eye and orbit
0.608 0.392 0.000
S04 Injury of cranial nerves
0.608 0.392 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.608 0.392 0.000
K35-K38 Diseases of appendix
0.608 0.392 0.000
S69 Other and unspecified injuries of wrist and hand
0.607 0.392 0.000
S68 Traumatic amputation of wrist and hand
0.607 0.392 0.000
S67 Crushing injury of wrist and hand
0.607 0.392 0.000
S65 Injury of blood vessels at wrist and hand level
0.607 0.392 0.000
S64 Injury of nerves at wrist and hand level
0.607 0.392 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.607 0.392 0.000
S60 Superficial injury of wrist and hand
0.607 0.392 0.000
O74 Complications of anaesthesia during labour and delivery
0.607 0.393 0.000
O73 Retained placenta and membranes, without haemorrhage
0.607 0.393 0.000
O71 Other obstetric trauma
0.607 0.393 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.607 0.393 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.607 0.393 0.000
O66 Other obstructed labour
0.607 0.393 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.607 0.393 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.607 0.393 0.000
O62 Abnormalities of forces of labour
0.607 0.393 0.000
O61 Failed induction of labour
0.607 0.393 0.000
O60 Preterm delivery
0.607 0.393 0.000
S72 Fracture of femur
0.606 0.393 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.606 0.394 0.000
Z09.4 Follow-up examination after treatment of fracture
0.606 0.394 0.000
Z09.3 Follow-up examination after psychotherapy
0.606 0.394 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.606 0.394 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.605 0.395 0.000
O07 Failed attempted abortion
0.605 0.395 0.000
O06 Unspecified abortion
0.605 0.395 0.000
O05 Other abortion
0.605 0.395 0.000
O01 Hydatidiform mole
0.605 0.395 0.000
O00 Ectopic pregnancy
0.605 0.395 0.000
S42 Fracture of shoulder and upper arm
0.602 0.398 0.000
O04 Medical abortion
0.602 0.398 0.000
C64-C68 Malignant neoplasms of urinary tract
0.602 0.398 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.601 0.399 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.601 0.399 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.601 0.399 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.601 0.399 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.601 0.399 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.601 0.399 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.601 0.399 0.000
N94.6 Dysmenorrhoea, unspecified
0.599 0.401 0.000
E10-E14 Diabetes mellitus
0.599 0.401 0.000
S29 Other and unspecified injuries of thorax
0.598 0.402 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.598 0.402 0.000
S27 Injury of other and unspecified intrathoracic organs
0.598 0.402 0.000
S26 Injury of heart
0.598 0.402 0.000
S25 Injury of blood vessels of thorax
0.598 0.402 0.000
S24 Injury of nerves and spinal cord at thorax level
0.598 0.402 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.598 0.402 0.000
S21 Open wound of thorax
0.598 0.402 0.000
S20 Superficial injury of thorax
0.598 0.402 0.000
D69.6 Thrombocytopenia, unspecified
0.597 0.403 0.000
B99-B99 Other infectious diseases
0.597 0.403 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.597 0.403 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.597 0.403 0.000
B65-B83 Helminthiases
0.597 0.403 0.000
B50-B64 Protozoal diseases
0.597 0.403 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.597 0.403 0.000
B15-B19 Viral hepatitis
0.597 0.403 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.597 0.403 0.000
A80-A89 Viral infections of the central nervous system
0.597 0.403 0.000
A75-A79 Rickettsioses
0.597 0.403 0.000
A70-A74 Other diseases caused by chlamydiae
0.597 0.403 0.000
A65-A69 Other spirochaetal diseases
0.597 0.403 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.597 0.403 0.000
A20-A28 Certain zoonotic bacterial diseases
0.597 0.403 0.000
A15-A19 Tuberculosis
0.597 0.403 0.000
Z98.8 Other specified postsurgical states
0.596 0.404 0.000
T31 Burns classified according to extent of body surface involved
0.595 0.405 0.000
H04.2 Epiphora
0.592 0.408 0.000
G90-G99 Other disorders of the nervous system
0.592 0.408 0.000
Z34 Supervision of normal pregnancy
0.590 0.410 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.590 0.410 0.000
H04.1 Other disorders of lachrymal gland
0.586 0.414 0.000
Z39 Postpartum care and examination
0.585 0.415 0.000
Z38 Liveborn infants according to place of birth
0.585 0.415 0.000
Z35 Supervision of high-risk pregnancy
0.585 0.415 0.000
Z32 Pregnancy examination and test
0.585 0.415 0.000
Z31 Procreative management
0.585 0.415 0.000
Z33 Pregnant state, incidental
0.585 0.415 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.585 0.415 0.000
G70-G73 Diseases of myoneural junction and muscle
0.584 0.416 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.584 0.416 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.584 0.416 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.584 0.416 0.000
T81.9 Unspecified complication of procedure
0.583 0.417 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.583 0.417 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.583 0.417 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.583 0.417 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.583 0.417 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.581 0.419 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.581 0.419 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.581 0.419 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.580 0.420 0.000
Z80.3 Family history of malignant neoplasm of breast
0.579 0.421 0.000
D64.9 Anaemia, unspecified
0.578 0.422 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.577 0.422 0.000
O80 Single spontaneous delivery
0.577 0.423 0.000
K90.0 Coeliac disease
0.575 0.425 0.000
Z88.5 Personal history of allergy to narcotic agent
0.575 0.425 0.000
S61.8 Open wound of other parts of wrist and hand
0.575 0.425 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.575 0.425 0.000
Y84.8 Other medical procedures
0.573 0.427 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.572 0.428 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.572 0.428 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.571 0.428 0.000
S09 Other and unspecified injuries of head
0.570 0.430 0.000
Z98.1 Arthrodesis status
0.570 0.430 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.570 0.430 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.569 0.431 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.569 0.431 0.000
N06 Isolated proteinuria with specified morphological lesion
0.569 0.431 0.000
N05 Unspecified nephritic syndrome
0.569 0.431 0.000
N04 Nephrotic syndrome
0.569 0.431 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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