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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77821460
log Bayes Factor = 20.1742
Chromosome 12   position 20,274,936  (GRCh37) Explore rs77821460 on Ensembl!
Variant rs77821460 is part of Cluster X0176

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
B95-B98 Bacterial, viral and other infectious agents
0.998 0.002 0.000
N17-N19 Renal failure
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.996 0.004 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.995 0.005 0.000
E11 Non-insulin-dependent diabetes mellitus
0.991 0.009 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.991 0.009 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.987 0.013 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.983 0.017 0.000
N20-N23 Urolithiasis
0.982 0.018 0.000
Chapter XI Diseases of the digestive system
0.980 0.020 0.000
K55-K64 Other diseases of intestines
0.977 0.023 0.000
E11.9 Without complications
0.977 0.023 0.000
N17 Acute renal failure
0.976 0.024 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.974 0.026 0.000
D10-D36 Benign neoplasms
0.972 0.028 0.000
Chapter VII Diseases of the eye and adnexa
0.971 0.029 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.971 0.029 0.000
N60-N64 Disorders of breast
0.968 0.032 0.000
K63 Other diseases of intestine
0.967 0.033 0.000
K63.5 Polyp of colon
0.964 0.036 0.000
N17.9 Acute renal failure, unspecified
0.961 0.039 0.000
N20 Calculus of kidney and ureter
0.959 0.041 0.000
N18 Chronic renal failure
0.958 0.042 0.000
K58 Irritable bowel syndrome
0.957 0.043 0.000
C79 Secondary malignant neoplasm of other sites
0.956 0.044 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.951 0.049 0.000
N20.0 Calculus of kidney
0.942 0.058 0.000
K70-K77 Diseases of liver
0.941 0.059 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.938 0.062 0.000
Chapter VIII Diseases of the ear and mastoid process
0.936 0.064 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.932 0.068 0.000
C50-C50 Malignant neoplasm of breast
0.932 0.068 0.000
C77.2 Intra-abdominal lymph nodes
0.924 0.076 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.916 0.084 0.000
D12.8 Rectum
0.913 0.087 0.000
E70-E90 Metabolic disorders
0.912 0.088 0.000
E00-E07 Disorders of thyroid gland
0.909 0.091 0.000
N60 Benign mammary dysplasia
0.908 0.092 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.908 0.092 0.000
L60-L75 Disorders of skin appendages
0.907 0.093 0.000
H25-H28 Disorders of lens
0.907 0.093 0.000
N10-N16 Renal tubulo-interstitial diseases
0.901 0.099 0.000
D17 Benign lipomatous neoplasm
0.898 0.102 0.000
E14 Unspecified diabetes mellitus
0.898 0.102 0.000
O42 Premature rupture of membranes
0.896 0.104 0.000
O80-O84 Delivery
0.895 0.105 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.894 0.106 0.000
K65-K67 Diseases of peritoneum
0.890 0.110 0.000
A00-A09 Intestinal infectious diseases
0.890 0.110 0.000
Chapter X Diseases of the respiratory system
0.886 0.114 0.000
D00-D09 In situ neoplasms
0.885 0.115 0.000
C50 Malignant neoplasm of breast
0.884 0.116 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.883 0.117 0.000
C64-C68 Malignant neoplasms of urinary tract
0.882 0.118 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.882 0.118 0.000
H25 Senile cataract
0.878 0.122 0.000
E11.5 With peripheral circulatory complications
0.875 0.125 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.874 0.126 0.000
D23 Other benign neoplasms of skin
0.874 0.126 0.000
C77.0 Lymph nodes of head, face and neck
0.868 0.132 0.000
Chapter XXI Factors influencing health status and contact with health services
0.866 0.134 0.000
H40-H42 Glaucoma
0.866 0.134 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.862 0.138 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.860 0.140 0.000
E11.4 With neurological complications
0.855 0.145 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.855 0.145 0.000
N64 Other disorders of breast
0.854 0.146 0.000
C77.3 Axillary and upper limb lymph nodes
0.853 0.146 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.852 0.148 0.000
O42.9 Premature rupture of membranes, unspecified
0.851 0.149 0.000
S70-S79 Injuries to the hip and thigh
0.851 0.149 0.000
H55-H59 Other disorders of eye and adnexa
0.850 0.150 0.000
K70 Alcoholic liver disease
0.848 0.152 0.000
Z30 Contraceptive management
0.846 0.154 0.000
E83 Disorders of mineral metabolism
0.846 0.154 0.000
N13 Obstructive and reflux uropathy
0.845 0.155 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.845 0.155 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.844 0.156 0.000
L20-L30 Dermatitis and eczema
0.843 0.157 0.000
O47 False labour
0.838 0.162 0.000
L03 Cellulitis
0.836 0.164 0.000
Y43 Primarily systemic agents
0.835 0.165 0.000
L72.1 Trichilemmal cyst
0.835 0.165 0.000
N21 Calculus of lower urinary tract
0.834 0.166 0.000
H65-H75 Diseases of middle ear and mastoid
0.834 0.166 0.000
O80 Single spontaneous delivery
0.834 0.166 0.000
Chapter V Mental and behavioural disorders
0.832 0.168 0.000
D12.0 Caecum
0.832 0.168 0.000
N18.0 End-stage renal disease
0.832 0.168 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.824 0.176 0.000
N18.4 Chronic kidney disease, stage 4
0.823 0.177 0.000
N60.4 Mammary duct ectasia
0.822 0.178 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.821 0.179 0.000
W20-W49 Exposure to inanimate mechanical forces
0.821 0.179 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.820 0.180 0.000
S80-S89 Injuries to the knee and lower leg
0.818 0.182 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.811 0.189 0.000
D80-D89 Certain disorders involving the immune mechanism
0.810 0.190 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.810 0.190 0.000
E40-E46 Malnutrition
0.810 0.190 0.000
N19 Unspecified renal failure
0.808 0.192 0.000
H25.0 Senile incipient cataract
0.808 0.192 0.000
S60-S69 Injuries to the wrist and hand
0.803 0.197 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.803 0.197 0.000
S20-S29 Injuries to the thorax
0.803 0.197 0.000
N62 Hypertrophy of breast
0.801 0.199 0.000
D70 Agranulocytosis
0.799 0.201 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.798 0.202 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.795 0.205 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.795 0.205 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.794 0.206 0.000
B35-B49 Mycoses
0.793 0.207 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.792 0.208 0.000
O80.0 Spontaneous vertex delivery
0.792 0.208 0.000
E14.9 Without complications
0.791 0.209 0.000
H40 Glaucoma
0.791 0.209 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.787 0.213 0.000
E04 Other non-toxic goitre
0.786 0.214 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.786 0.214 0.000
Z35 Supervision of high-risk pregnancy
0.785 0.215 0.000
D60-D64 Aplastic and other anaemias
0.782 0.218 0.000
K72 Hepatic failure, not elsewhere classified
0.782 0.218 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.781 0.219 0.000
O36 Maternal care for other known or suspected foetal problems
0.781 0.219 0.000
D23.1 Skin of eyelid, including canthus
0.780 0.220 0.000
T66-T78 Other and unspecified effects of external causes
0.780 0.220 0.000
K55 Vascular disorders of intestine
0.780 0.220 0.000
X60-X84 Intentional self-harm
0.779 0.221 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.779 0.221 0.000
C77.1 Intrathoracic lymph nodes
0.777 0.223 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.777 0.223 0.000
Y57 Other and unspecified drugs and medicaments
0.776 0.224 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.776 0.224 0.000
N18.5 Chronic kidney disease, stage 5
0.775 0.225 0.000
N18.2 Chronic kidney disease, stage 2
0.775 0.225 0.000
D12.5 Sigmoid colon
0.775 0.225 0.000
K75 Other inflammatory liver diseases
0.774 0.226 0.000
E11.2 With renal complications
0.774 0.226 0.000
K66 Other disorders of peritoneum
0.773 0.227 0.000
H25.9 Senile cataract, unspecified
0.773 0.227 0.000
A80-A89 Viral infections of the central nervous system
0.772 0.228 0.000
H90-H95 Other disorders of ear
0.771 0.229 0.000
D05 Carcinoma in situ of breast
0.769 0.231 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.768 0.232 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.768 0.232 0.000
C77.5 Intrapelvic lymph nodes
0.767 0.233 0.000
D50-D53 Nutritional anaemias
0.766 0.234 0.000
Y43.3 Other antineoplastic drugs
0.766 0.234 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.765 0.235 0.000
E13 Other specified diabetes mellitus
0.765 0.235 0.000
E06 Thyroiditis
0.764 0.236 0.000
L89 Decubitus ulcer
0.763 0.236 0.000
H55 Nystagmus and other irregular eye movements
0.763 0.237 0.000
A30-A49 Other bacterial diseases
0.763 0.237 0.000
J95-J99 Other diseases of the respiratory system
0.762 0.238 0.000
O30 Multiple gestation
0.760 0.240 0.000
C50.9 Breast, unspecified
0.760 0.240 0.000
Z36 Antenatal screening
0.759 0.241 0.000
S00-S09 Injuries to the head
0.758 0.242 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.757 0.243 0.000
N64.8 Other specified disorders of breast
0.756 0.244 0.000
H25.8 Other senile cataract
0.755 0.245 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.755 0.245 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.754 0.246 0.000
D75 Other diseases of blood and blood-forming organs
0.754 0.246 0.000
C79.2 Secondary malignant neoplasm of skin
0.752 0.247 0.000
K65 Peritonitis
0.752 0.248 0.000
C50.2 Upper-inner quadrant of breast
0.751 0.249 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.750 0.250 0.000
S50-S59 Injuries to the elbow and forearm
0.749 0.250 0.000
C67 Malignant neoplasm of bladder
0.748 0.252 0.000
C77.9 Lymph node, unspecified
0.747 0.253 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.747 0.253 0.000
D10 Benign neoplasm of mouth and pharynx
0.746 0.254 0.000
N00-N08 Glomerular diseases
0.744 0.256 0.000
J00-J06 Acute upper respiratory infections
0.743 0.256 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.743 0.257 0.000
L05 Pilonidal cyst
0.743 0.257 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.743 0.257 0.000
B15-B19 Viral hepatitis
0.742 0.257 0.000
H80-H83 Diseases of inner ear
0.742 0.258 0.000
K70.9 Alcoholic liver disease, unspecified
0.741 0.259 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.740 0.260 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.740 0.260 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.740 0.260 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.739 0.260 0.000
V10-V19 Pedal cyclist injured in transport accident
0.738 0.262 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.737 0.263 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.736 0.264 0.000
N60.2 Fibroadenosis of breast
0.736 0.264 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.734 0.266 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.732 0.268 0.000
B25-B34 Other viral diseases
0.731 0.269 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.731 0.269 0.000
L03.3 Cellulitis of trunk
0.729 0.271 0.000
E14.3 With ophthalmic complications
0.729 0.271 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.728 0.272 0.000
N21.0 Calculus in bladder
0.728 0.272 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.728 0.272 0.000
D12.7 Rectosigmoid junction
0.728 0.272 0.000
N18.9 Chronic renal failure, unspecified
0.727 0.272 0.000
D23.4 Skin of scalp and neck
0.727 0.273 0.000
E83.5 Disorders of calcium metabolism
0.727 0.273 0.000
H65 Nonsuppurative otitis media
0.727 0.273 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.726 0.274 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.726 0.274 0.000
D73 Diseases of spleen
0.726 0.274 0.000
A04 Other bacterial intestinal infections
0.724 0.276 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.723 0.277 0.000
K63.9 Disease of intestine, unspecified
0.723 0.277 0.000
C50.0 Nipple and areola
0.722 0.278 0.000
L29 Pruritus
0.720 0.280 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.720 0.280 0.000
O00-O08 Pregnancy with abortive outcome
0.720 0.280 0.000
D12.6 Colon, unspecified
0.720 0.280 0.000
S40-S49 Injuries to the shoulder and upper arm
0.719 0.281 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.717 0.283 0.000
C80 Malignant neoplasm without specification of site
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
A08 Viral and other specified intestinal infections
0.716 0.284 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.284 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.715 0.285 0.000
S72 Fracture of femur
0.715 0.285 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.286 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.714 0.286 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.713 0.287 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.713 0.287 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.713 0.287 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.713 0.287 0.000
D34 Benign neoplasm of thyroid gland
0.712 0.287 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.712 0.288 0.000
E11.8 With unspecified complications
0.711 0.289 0.000
E11.7 With multiple complications
0.711 0.289 0.000
E11.6 With other specified complications
0.711 0.289 0.000
E11.1 With ketoacidosis
0.711 0.289 0.000
E11.0 With coma
0.711 0.289 0.000
O85-O92 Complications predominantly related to the puerperium
0.711 0.289 0.000
N13.6 Pyonephrosis
0.711 0.289 0.000
C50.1 Central portion of breast
0.710 0.290 0.000
S90-S99 Injuries to the ankle and foot
0.710 0.290 0.000
E89.0 Postprocedural hypothyroidism
0.710 0.290 0.000
E03 Other hypothyroidism
0.709 0.291 0.000
L50-L54 Urticaria and erythema
0.709 0.291 0.000
C77.8 Lymph nodes of multiple regions
0.709 0.291 0.000
C77.4 Inguinal and lower limb lymph nodes
0.709 0.291 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.709 0.291 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.709 0.291 0.000
L10-L14 Bullous disorders
0.707 0.293 0.000
N23 Unspecified renal colic
0.707 0.293 0.000
D12.3 Transverse colon
0.707 0.293 0.000
D32 Benign neoplasm of meninges
0.706 0.294 0.000
D24 Benign neoplasm of breast
0.706 0.294 0.000
T79-T79 Certain early complications of trauma
0.706 0.294 0.000
T33-T35 Frostbite
0.706 0.294 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.706 0.294 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.706 0.294 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.706 0.294 0.000
T00-T07 Injuries involving multiple body regions
0.706 0.294 0.000
S10-S19 Injuries to the neck
0.706 0.294 0.000
K56.6 Other and unspecified intestinal obstruction
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.704 0.296 0.000
N60.3 Fibrosclerosis of breast
0.704 0.296 0.000
K74 Fibrosis and cirrhosis of liver
0.702 0.297 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
K63.2 Fistula of intestine
0.701 0.299 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.701 0.299 0.000
N25-N29 Other disorders of kidney and ureter
0.700 0.299 0.000
D36 Benign neoplasm of other and unspecified sites
0.700 0.300 0.000
K76 Other diseases of liver
0.700 0.300 0.000
H40.9 Glaucoma, unspecified
0.700 0.300 0.000
N17.8 Other acute renal failure
0.700 0.300 0.000
N17.2 Acute renal failure with medullary necrosis
0.700 0.300 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.700 0.300 0.000
N17.0 Acute renal failure with tubular necrosis
0.700 0.300 0.000
C78.7 Secondary malignant neoplasm of liver
0.700 0.300 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.699 0.301 0.000
K70.3 Alcoholic cirrhosis of liver
0.699 0.301 0.000
E88 Other metabolic disorders
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.301 0.000
C50.3 Lower-inner quadrant of breast
0.698 0.302 0.000
D55-D59 Haemolytic anaemias
0.698 0.302 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.698 0.302 0.000
D31 Benign neoplasm of eye and adnexa
0.697 0.303 0.000
D30 Benign neoplasm of urinary organs
0.697 0.303 0.000
D29 Benign neoplasm of male genital organs
0.697 0.303 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.697 0.303 0.000
D26 Other benign neoplasms of uterus
0.697 0.303 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.697 0.303 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.697 0.303 0.000
D19 Benign neoplasm of mesothelial tissue
0.697 0.303 0.000
D16 Benign neoplasm of bone and articular cartilage
0.697 0.303 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.697 0.303 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.697 0.303 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.696 0.304 0.000
H10-H13 Disorders of conjunctiva
0.696 0.304 0.000
O45 Premature separation of placenta [abruptio placentae]
0.696 0.304 0.000
O44 Placenta praevia
0.696 0.304 0.000
O43 Placental disorders
0.696 0.304 0.000
O41 Other disorders of amniotic fluid and membranes
0.696 0.304 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.696 0.304 0.000
O33 Maternal care for known or suspected disproportion
0.696 0.304 0.000
O31 Complications specific to multiple gestation
0.696 0.304 0.000
O40 Polyhydramnios
0.696 0.304 0.000
J30-J39 Other diseases of upper respiratory tract
0.696 0.304 0.000
D09 Carcinoma in situ of other and unspecified sites
0.695 0.304 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.695 0.305 0.000
K63.4 Enteroptosis
0.694 0.306 0.000
K63.0 Abscess of intestine
0.694 0.306 0.000
E87.5 Hyperkalaemia
0.693 0.306 0.000
D86 Sarcoidosis
0.693 0.307 0.000
E83.3 Disorders of phosphorus metabolism
0.693 0.307 0.000
J20-J22 Other acute lower respiratory infections
0.691 0.309 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.688 0.312 0.000
N20.9 Urinary calculus, unspecified
0.687 0.313 0.000
N20.2 Calculus of kidney with calculus of ureter
0.687 0.313 0.000
N18.8 Other chronic renal failure
0.687 0.313 0.000
N18.1 Chronic kidney disease, stage 1
0.687 0.313 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.687 0.313 0.000
N99-N99 Other disorders of the genitourinary system
0.686 0.314 0.000
N95 Menopausal and other perimenopausal disorders
0.686 0.314 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.686 0.314 0.000
C79.6 Secondary malignant neoplasm of ovary
0.686 0.314 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.686 0.314 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.686 0.314 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.686 0.314 0.000
Y40 Systemic antibiotics
0.685 0.315 0.000
L08 Other local infections of skin and subcutaneous tissue
0.685 0.315 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.685 0.315 0.000
D45 Polycythaemia vera
0.685 0.315 0.000
O60-O75 Complications of labour and delivery
0.684 0.316 0.000
L03.0 Cellulitis of finger and toe
0.684 0.316 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.683 0.317 0.000
D12.9 Anus and anal canal
0.682 0.318 0.000
D12.1 Appendix
0.682 0.318 0.000
K50-K52 Noninfective enteritis and colitis
0.682 0.318 0.000
E50-E64 Other nutritional deficiencies
0.681 0.319 0.000
C15-C26 Malignant neoplasms of digestive organs
0.681 0.319 0.000
S70 Superficial injury of hip and thigh
0.681 0.319 0.000
L73 Other follicular disorders
0.681 0.319 0.000
N61 Inflammatory disorders of breast
0.679 0.320 0.000
W25 Contact with sharp glass
0.679 0.320 0.000
C78.0 Secondary malignant neoplasm of lung
0.679 0.321 0.000
H60-H62 Diseases of external ear
0.679 0.321 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.678 0.322 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.677 0.323 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.677 0.323 0.000
E04.9 Non-toxic goitre, unspecified
0.677 0.323 0.000
D18 Haemangioma and lymphangioma, any site
0.676 0.323 0.000
N64.9 Disorder of breast, unspecified
0.676 0.324 0.000
N20.1 Calculus of ureter
0.676 0.324 0.000
H40.0 Glaucoma suspect
0.676 0.324 0.000
C50.8 Overlapping lesion of breast
0.675 0.325 0.000
K77 Liver disorders in diseases classified elsewhere
0.675 0.325 0.000
K73 Chronic hepatitis, not elsewhere classified
0.675 0.325 0.000
K71 Toxic liver disease
0.675 0.325 0.000
J98 Other respiratory disorders
0.674 0.326 0.000
L90 Atrophic disorders of skin
0.674 0.326 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.674 0.326 0.000
E46 Unspecified protein-energy malnutrition
0.674 0.326 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.672 0.328 0.000
K35-K38 Diseases of appendix
0.672 0.328 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.672 0.328 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.671 0.328 0.000
D23.7 Skin of lower limb, including hip
0.670 0.330 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.670 0.330 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.670 0.330 0.000
H43-H45 Disorders of vitreous body and globe
0.668 0.331 0.000
Y59 Other and unspecified vaccines and biological substances
0.668 0.332 0.000
Y58 Bacterial vaccines
0.668 0.332 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.668 0.332 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.668 0.332 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.668 0.332 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.668 0.332 0.000
Y52 Agents primarily affecting the cardiovascular system
0.668 0.332 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.668 0.332 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.668 0.332 0.000
Y48 Anaesthetics and therapeutic gases
0.668 0.332 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.668 0.332 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.668 0.332 0.000
Y44 Agents primarily affecting blood constituents
0.668 0.332 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.668 0.332 0.000
D04 Carcinoma in situ of skin
0.668 0.332 0.000
K72.9 Hepatic failure, unspecified
0.668 0.332 0.000
D11 Benign neoplasm of major salivary glands
0.668 0.332 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.667 0.333 0.000
H72 Perforation of tympanic membrane
0.667 0.333 0.000
N60.1 Diffuse cystic mastopathy
0.666 0.334 0.000
E20-E35 Disorders of other endocrine glands
0.666 0.334 0.000
J02 Acute pharyngitis
0.664 0.336 0.000
Y57.9 Drug or medicament, unspecified
0.664 0.336 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.661 0.339 0.000
E06.3 Autoimmune thyroiditis
0.660 0.340 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.660 0.340 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.659 0.341 0.000
O47.0 False labour before 37 completed weeks of gestation
0.659 0.341 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.658 0.341 0.000
E83.1 Disorders of iron metabolism
0.658 0.342 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.657 0.343 0.000
L04 Acute lymphadenitis
0.656 0.343 0.000
L01 Impetigo
0.656 0.343 0.000
L00 Staphylococcal scalded skin syndrome
0.656 0.343 0.000
D23.6 Skin of upper limb, including shoulder
0.656 0.344 0.000
K75.4 Autoimmune hepatitis
0.655 0.345 0.000
Z35.5 Supervision of elderly primigravida
0.655 0.345 0.000
K63.8 Other specified diseases of intestine
0.654 0.345 0.000
E85 Amyloidosis
0.654 0.346 0.000
E84 Cystic fibrosis
0.654 0.346 0.000
E79 Disorders of purine and pyrimidine metabolism
0.654 0.346 0.000
E77 Disorders of glycoprotein metabolism
0.654 0.346 0.000
E76 Disorders of glycosaminoglycan metabolism
0.654 0.346 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.654 0.346 0.000
E74 Other disorders of carbohydrate metabolism
0.654 0.346 0.000
E73 Lactose intolerance
0.654 0.346 0.000
E72 Other disorders of amino-acid metabolism
0.654 0.346 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.654 0.346 0.000
E70 Disorders of aromatic amino-acid metabolism
0.654 0.346 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.654 0.346 0.000
K65.0 Acute peritonitis
0.653 0.347 0.000
E83.4 Disorders of magnesium metabolism
0.653 0.347 0.000
K56.4 Other impaction of intestine
0.653 0.347 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.652 0.348 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.652 0.348 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.651 0.348 0.000
E00 Congenital iodine-deficiency syndrome
0.651 0.348 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.651 0.348 0.000
L89.1 Stage II decubitus ulcer
0.651 0.349 0.000
N60.9 Benign mammary dysplasia, unspecified
0.651 0.349 0.000
N60.8 Other benign mammary dysplasias
0.651 0.349 0.000
N60.0 Solitary cyst of breast
0.651 0.349 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.651 0.349 0.000
D74 Methaemoglobinaemia
0.651 0.349 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.651 0.349 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.651 0.349 0.000
J81 Pulmonary oedema
0.650 0.350 0.000
L75 Apocrine sweat disorders
0.650 0.350 0.000
L74 Eccrine sweat disorders
0.650 0.350 0.000
L71 Rosacea
0.650 0.350 0.000
L70 Acne
0.650 0.350 0.000
L68 Hypertrichosis
0.650 0.350 0.000
L67 Hair colour and hair shaft abnormalities
0.650 0.350 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.650 0.350 0.000
L65 Other nonscarring hair loss
0.650 0.350 0.000
L64 Androgenic alopecia
0.650 0.350 0.000
L63 Alopecia areata
0.650 0.350 0.000
L62 Nail disorders in diseases classified elsewhere
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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