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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77955651
log Bayes Factor = 12.6473
Chromosome 7   position 48,056,220  (GRCh37) Explore rs77955651 on Ensembl!
Variant rs77955651 is part of Cluster X0171

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
M06.9 Rheumatoid arthritis, unspecified
0.996 0.004 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.992 0.008 0.000
S00-S09 Injuries to the head
0.992 0.008 0.000
I50 Heart failure
0.989 0.011 0.000
M80-M85 Disorders of bone density and structure
0.986 0.014 0.000
O60-O75 Complications of labour and delivery
0.980 0.020 0.000
S20-S29 Injuries to the thorax
0.979 0.021 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.975 0.025 0.000
M70-M79 Other soft tissue disorders
0.973 0.027 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.970 0.030 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.969 0.031 0.000
R26 Abnormalities of gait and mobility
0.961 0.039 0.000
I45 Other conduction disorders
0.960 0.040 0.000
M81 Osteoporosis without pathological fracture
0.959 0.041 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.953 0.047 0.000
O36 Maternal care for other known or suspected foetal problems
0.952 0.048 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.949 0.051 0.000
I49 Other cardiac arrhythmias
0.943 0.057 0.000
I50.1 Left ventricular failure
0.942 0.058 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.940 0.060 0.000
M81.9 Osteoporosis, unspecified
0.938 0.062 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.938 0.062 0.000
S06 Intracranial injury
0.927 0.073 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.926 0.074 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.921 0.079 0.000
Chapter I Certain infectious and parasitic diseases
0.921 0.079 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.919 0.081 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.917 0.083 0.000
I51 Complications and ill-defined descriptions of heart disease
0.914 0.086 0.000
I45.1 Other and unspecified right bundle-branch block
0.910 0.090 0.000
Chapter VI Diseases of the nervous system
0.908 0.092 0.000
M72 Fibroblastic disorders
0.904 0.096 0.000
O47 False labour
0.903 0.097 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.902 0.098 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.900 0.100 0.000
I50.9 Heart failure, unspecified
0.899 0.101 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.898 0.102 0.000
Chapter XX External causes of morbidity and mortality
0.896 0.104 0.000
S09 Other and unspecified injuries of head
0.892 0.108 0.000
S60-S69 Injuries to the wrist and hand
0.891 0.109 0.000
M86-M90 Other osteopathies
0.891 0.109 0.000
O36.5 Maternal care for poor foetal growth
0.887 0.113 0.000
S22.4 Multiple fractures of ribs
0.886 0.114 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.879 0.121 0.000
S27 Injury of other and unspecified intrathoracic organs
0.876 0.124 0.000
B25-B34 Other viral diseases
0.875 0.124 0.000
O41 Other disorders of amniotic fluid and membranes
0.875 0.125 0.000
S02 Fracture of skull and facial bones
0.871 0.129 0.000
I05-I09 Chronic rheumatic heart diseases
0.867 0.132 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.864 0.136 0.000
S10-S19 Injuries to the neck
0.863 0.137 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.862 0.138 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.860 0.140 0.000
S22.40 Multiple fractures of ribs (closed)
0.858 0.142 0.000
M79.6 Pain in limb
0.857 0.143 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.855 0.145 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.855 0.145 0.000
I50.0 Congestive heart failure
0.854 0.146 0.000
I49.3 Ventricular premature depolarisation
0.854 0.146 0.000
Chapter V Mental and behavioural disorders
0.850 0.150 0.000
M50-M54 Other dorsopathies
0.850 0.150 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.849 0.151 0.000
I36 Nonrheumatic tricuspid valve disorders
0.848 0.152 0.000
I60-I69 Cerebrovascular diseases
0.848 0.152 0.000
S90-S99 Injuries to the ankle and foot
0.846 0.154 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.844 0.156 0.000
M10 Gout
0.843 0.157 0.000
M81.98 Osteoporosis, unspecified (Other)
0.842 0.158 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.841 0.159 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.837 0.163 0.000
O44 Placenta praevia
0.833 0.167 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.833 0.167 0.000
B34 Viral infection of unspecified site
0.827 0.173 0.000
O75.8 Other specified complications of labour and delivery
0.825 0.175 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.824 0.176 0.000
Chapter VII Diseases of the eye and adnexa
0.823 0.177 0.000
R26.3 Immobility
0.823 0.177 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.823 0.177 0.000
S09.9 Unspecified injury of head
0.820 0.180 0.000
Y86 Sequelae of other accidents
0.818 0.182 0.000
M06.0 Seronegative rheumatoid arthritis
0.818 0.182 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.816 0.183 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.815 0.185 0.000
M84 Disorders of continuity of bone
0.814 0.186 0.000
G82 Paraplegia and tetraplegia
0.813 0.187 0.000
I42 Cardiomyopathy
0.813 0.187 0.000
R29.6 Tendency to fall, not elsewhere classified
0.810 0.190 0.000
M79.1 Myalgia
0.809 0.191 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.809 0.191 0.000
H30-H36 Disorders of choroid and retina
0.807 0.193 0.000
O36.8 Maternal care for other specified foetal problems
0.806 0.194 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.805 0.195 0.000
O63 Long labour
0.805 0.195 0.000
M54 Dorsalgia
0.805 0.195 0.000
Chapter XXII Codes for special purposes
0.805 0.195 0.000
M65-M68 Disorders of synovium and tendon
0.804 0.196 0.000
S00 Superficial injury of head
0.800 0.200 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.799 0.201 0.000
O62 Abnormalities of forces of labour
0.798 0.202 0.000
M85 Other disorders of bone density and structure
0.798 0.202 0.000
M13 Other arthritis
0.797 0.203 0.000
I49.8 Other specified cardiac arrhythmias
0.795 0.204 0.000
M05 Seropositive rheumatoid arthritis
0.795 0.205 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.793 0.207 0.000
B34.9 Viral infection, unspecified
0.792 0.208 0.000
B35-B49 Mycoses
0.791 0.209 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.788 0.212 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.788 0.212 0.000
I45.8 Other specified conduction disorders
0.785 0.215 0.000
M79.60 Pain in limb (Multiple sites)
0.783 0.217 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.781 0.219 0.000
S06.5 Traumatic subdural haemorrhage
0.780 0.220 0.000
S27.3 Other injuries of lung
0.777 0.223 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.777 0.223 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.776 0.224 0.000
S64 Injury of nerves at wrist and hand level
0.775 0.225 0.000
S20 Superficial injury of thorax
0.774 0.226 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.773 0.227 0.000
I47 Paroxysmal tachycardia
0.772 0.228 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.771 0.228 0.000
I07 Rheumatic tricuspid valve diseases
0.770 0.230 0.000
M45-M49 Spondylopathies
0.769 0.231 0.000
M89 Other disorders of bone
0.766 0.233 0.000
M79.8 Other specified soft tissue disorders
0.765 0.235 0.000
R44.1 Visual hallucinations
0.765 0.235 0.000
T91 Sequelae of injuries of neck and trunk
0.764 0.236 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.762 0.237 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.762 0.238 0.000
I49.9 Cardiac arrhythmia, unspecified
0.762 0.238 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.760 0.240 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.760 0.240 0.000
M40-M43 Deforming dorsopathies
0.758 0.242 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.757 0.243 0.000
F30-F39 Mood [affective] disorders
0.757 0.243 0.000
I51.7 Cardiomegaly
0.756 0.244 0.000
O41.0 Oligohydramnios
0.756 0.244 0.000
S40-S49 Injuries to the shoulder and upper arm
0.755 0.245 0.000
I49.4 Other and unspecified premature depolarisation
0.755 0.245 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.754 0.246 0.000
S06.2 Diffuse brain injury
0.753 0.247 0.000
I71 Aortic aneurysm and dissection
0.753 0.247 0.000
I51.4 Myocarditis, unspecified
0.753 0.247 0.000
S70-S79 Injuries to the hip and thigh
0.750 0.250 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.750 0.250 0.000
M79.67 Pain in limb (Ankle and foot)
0.748 0.252 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.748 0.252 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.747 0.253 0.000
I51.8 Other ill-defined heart diseases
0.747 0.253 0.000
M80 Osteoporosis with pathological fracture
0.746 0.254 0.000
W00-W19 Falls
0.746 0.254 0.000
O30 Multiple gestation
0.745 0.254 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.745 0.255 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.744 0.256 0.000
S01 Open wound of head
0.743 0.257 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.742 0.258 0.000
M60-M63 Disorders of muscles
0.741 0.259 0.000
O36.9 Maternal care for foetal problem, unspecified
0.740 0.260 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.740 0.260 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.740 0.260 0.000
T90 Sequelae of injuries of head
0.738 0.262 0.000
T92 Sequelae of injuries of upper limb
0.738 0.262 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.738 0.262 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.738 0.262 0.000
I45.5 Other specified heart block
0.738 0.262 0.000
M00-M03 Infectious arthropathies
0.737 0.262 0.000
M79.69 Pain in limb (Site unspecified)
0.736 0.264 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.735 0.265 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.734 0.266 0.000
M77 Other enthesopathies
0.734 0.266 0.000
S50-S59 Injuries to the elbow and forearm
0.734 0.266 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.732 0.267 0.000
M10.9 Gout, unspecified
0.731 0.269 0.000
G82.2 Paraplegia, unspecified
0.730 0.270 0.000
S80-S89 Injuries to the knee and lower leg
0.727 0.273 0.000
I35 Nonrheumatic aortic valve disorders
0.727 0.273 0.000
M54.3 Sciatica
0.726 0.274 0.000
M54.1 Radiculopathy
0.726 0.274 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.726 0.274 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.725 0.275 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.725 0.275 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.724 0.276 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.723 0.277 0.000
S22.0 Fracture of thoracic vertebra
0.723 0.277 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.721 0.279 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.720 0.280 0.000
O44.1 Placenta praevia with haemorrhage
0.720 0.280 0.000
O75.0 Maternal distress during labour and delivery
0.720 0.280 0.000
T93 Sequelae of injuries of lower limb
0.720 0.280 0.000
H36 Retinal disorders in diseases classified elsewhere
0.719 0.281 0.000
S67 Crushing injury of wrist and hand
0.719 0.281 0.000
S06.8 Other intracranial injuries
0.718 0.282 0.000
M72.2 Plantar fascial fibromatosis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
R43 Disturbances of smell and taste
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.716 0.284 0.000
M06.8 Other specified rheumatoid arthritis
0.715 0.285 0.000
M06.4 Inflammatory polyarthropathy
0.715 0.285 0.000
M06.3 Rheumatoid nodule
0.715 0.285 0.000
M06.2 Rheumatoid bursitis
0.715 0.285 0.000
M06.1 Adult-onset Still's disease
0.715 0.285 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.714 0.286 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.714 0.286 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.714 0.286 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.714 0.286 0.000
O43 Placental disorders
0.714 0.286 0.000
I30 Acute pericarditis
0.712 0.288 0.000
O45 Premature separation of placenta [abruptio placentae]
0.711 0.289 0.000
O33 Maternal care for known or suspected disproportion
0.711 0.289 0.000
O31 Complications specific to multiple gestation
0.711 0.289 0.000
O40 Polyhydramnios
0.711 0.289 0.000
S08 Traumatic amputation of part of head
0.711 0.289 0.000
S07 Crushing injury of head
0.711 0.289 0.000
S05 Injury of eye and orbit
0.711 0.289 0.000
S04 Injury of cranial nerves
0.711 0.289 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.711 0.289 0.000
H35 Other retinal disorders
0.711 0.289 0.000
M71 Other bursopathies
0.711 0.289 0.000
M79.7 Fibromyalgia
0.709 0.291 0.000
S32 Fracture of lumbar spine and pelvis
0.709 0.291 0.000
B25 Cytomegaloviral disease
0.708 0.292 0.000
T17 Foreign body in respiratory tract
0.708 0.292 0.000
M83 Adult osteomalacia
0.707 0.293 0.000
M82 Osteoporosis in diseases classified elsewhere
0.707 0.293 0.000
M81.4 Drug-induced osteoporosis
0.706 0.294 0.000
I69 Sequelae of cerebrovascular disease
0.706 0.294 0.000
M88 Paget's disease of bone [osteitis deformans]
0.706 0.294 0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)
0.706 0.294 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.706 0.294 0.000
T66-T78 Other and unspecified effects of external causes
0.705 0.294 0.000
O74 Complications of anaesthesia during labour and delivery
0.702 0.297 0.000
O71 Other obstetric trauma
0.702 0.297 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.702 0.297 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.702 0.297 0.000
O61 Failed induction of labour
0.702 0.297 0.000
O60 Preterm delivery
0.702 0.297 0.000
S29 Other and unspecified injuries of thorax
0.702 0.298 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.702 0.298 0.000
S26 Injury of heart
0.702 0.298 0.000
S25 Injury of blood vessels of thorax
0.702 0.298 0.000
S24 Injury of nerves and spinal cord at thorax level
0.702 0.298 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.702 0.298 0.000
S21 Open wound of thorax
0.702 0.298 0.000
S02.0 Fracture of vault of skull
0.702 0.298 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.702 0.298 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.701 0.299 0.000
I07.1 Tricuspid insufficiency
0.700 0.300 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.700 0.300 0.000
S06.3 Focal brain injury
0.699 0.300 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.699 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.699 0.301 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.699 0.301 0.000
O00-O08 Pregnancy with abortive outcome
0.699 0.301 0.000
H33 Retinal detachments and breaks
0.699 0.301 0.000
M76 Enthesopathies of lower limb, excluding foot
0.698 0.302 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.698 0.302 0.000
R40 Somnolence, stupor and coma
0.698 0.302 0.000
S02.2 Fracture of nasal bones
0.697 0.303 0.000
V10-V19 Pedal cyclist injured in transport accident
0.695 0.305 0.000
Y85 Sequelae of transport accidents
0.695 0.305 0.000
Q60-Q64 Congenital malformations of the urinary system
0.694 0.305 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.694 0.305 0.000
I49.1 Atrial premature depolarisation
0.694 0.306 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.690 0.309 0.000
B99-B99 Other infectious diseases
0.690 0.310 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.689 0.311 0.000
R26.1 Paralytic gait
0.689 0.311 0.000
R26.0 Ataxic gait
0.689 0.311 0.000
I45.9 Conduction disorder, unspecified
0.688 0.311 0.000
I45.4 Nonspecific intraventricular block
0.688 0.311 0.000
I45.3 Trifascicular block
0.688 0.311 0.000
I45.2 Bifascicular block
0.688 0.311 0.000
I45.0 Right fascicular block
0.688 0.311 0.000
M81.8 Other osteoporosis
0.688 0.312 0.000
M81.6 Localised osteoporosis [Lequesne]
0.688 0.312 0.000
M81.5 Idiopathic osteoporosis
0.688 0.312 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.688 0.312 0.000
M81.2 Osteoporosis of disuse
0.688 0.312 0.000
M81.1 Postoophorectomy osteoporosis
0.688 0.312 0.000
M81.0 Postmenopausal osteoporosis
0.688 0.312 0.000
O70 Perineal laceration during delivery
0.687 0.313 0.000
O63.1 Prolonged second stage (of labour)
0.687 0.313 0.000
S90 Superficial injury of ankle and foot
0.687 0.313 0.000
I05 Rheumatic mitral valve diseases
0.686 0.314 0.000
X60-X84 Intentional self-harm
0.685 0.315 0.000
M79.64 Pain in limb (Hand)
0.684 0.316 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.683 0.317 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.683 0.317 0.000
O36.6 Maternal care for excessive foetal growth
0.683 0.317 0.000
O36.4 Maternal care for intra-uterine death
0.683 0.317 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.683 0.317 0.000
O36.2 Maternal care for hydrops foetalis
0.683 0.317 0.000
O36.1 Maternal care for other isoimmunisation
0.683 0.317 0.000
S02.1 Fracture of base of skull
0.682 0.318 0.000
T79-T79 Certain early complications of trauma
0.682 0.318 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.682 0.318 0.000
I47.1 Supraventricular tachycardia
0.681 0.319 0.000
G80 Infantile cerebral palsy
0.681 0.319 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.680 0.320 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.678 0.321 0.000
I45.6 Preexcitation syndrome
0.678 0.322 0.000
S14 Injury of nerves and spinal cord at neck level
0.678 0.322 0.000
M89.9 Disorder of bone, unspecified
0.678 0.322 0.000
G83 Other paralytic syndromes
0.677 0.323 0.000
M54.5 Low back pain
0.677 0.323 0.000
I49.2 Junctional premature depolarisation
0.676 0.324 0.000
S27.1 Traumatic haemothorax
0.675 0.325 0.000
I42.0 Dilated cardiomyopathy
0.675 0.325 0.000
R44.0 Auditory hallucinations
0.674 0.326 0.000
S00.5 Superficial injury of lip and oral cavity
0.674 0.326 0.000
I34 Nonrheumatic mitral valve disorders
0.674 0.326 0.000
I61 Intracerebral haemorrhage
0.674 0.326 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.674 0.326 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.674 0.326 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.674 0.326 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.674 0.326 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.674 0.326 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.674 0.326 0.000
T36 Poisoning by systemic antibiotics
0.674 0.326 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.674 0.326 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.674 0.326 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.673 0.327 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.673 0.327 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.673 0.327 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.673 0.327 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.673 0.327 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.673 0.327 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.673 0.327 0.000
M79.9 Soft tissue disorder, unspecified
0.673 0.327 0.000
M79.3 Panniculitis, unspecified
0.673 0.327 0.000
M79.2 Neuralgia and neuritis, unspecified
0.673 0.327 0.000
S12 Fracture of neck
0.673 0.327 0.000
M11 Other crystal arthropathies
0.672 0.328 0.000
M79.19 Myalgia (Site unspecified)
0.672 0.328 0.000
O66 Other obstructed labour
0.671 0.329 0.000
M86 Osteomyelitis
0.671 0.329 0.000
S10 Superficial injury of neck
0.670 0.330 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.670 0.330 0.000
O73 Retained placenta and membranes, without haemorrhage
0.668 0.332 0.000
I35.1 Aortic (valve) insufficiency
0.668 0.332 0.000
M90 Osteopathies in diseases classified elsewhere
0.667 0.333 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.667 0.333 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.666 0.334 0.000
I51.9 Heart disease, unspecified
0.666 0.334 0.000
S02.6 Fracture of mandible
0.665 0.334 0.000
G82.1 Spastic paraplegia
0.665 0.335 0.000
G82.5 Tetraplegia, unspecified
0.665 0.335 0.000
B35 Dermatophytosis
0.665 0.335 0.000
S06.9 Intracranial injury, unspecified
0.664 0.335 0.000
S06.7 Intracranial injury with prolonged coma
0.664 0.335 0.000
S06.4 Epidural haemorrhage
0.664 0.335 0.000
S06.1 Traumatic cerebral oedema
0.664 0.335 0.000
S06.0 Concussion
0.664 0.335 0.000
G90-G99 Other disorders of the nervous system
0.664 0.336 0.000
S22.9 Fracture of bony thorax, part unspecified
0.664 0.336 0.000
S22.8 Fracture of other parts of bony thorax
0.664 0.336 0.000
S22.5 Flail chest
0.664 0.336 0.000
S22.1 Multiple fractures of thoracic spine
0.664 0.336 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.663 0.336 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.663 0.337 0.000
R27 Other lack of coordination
0.663 0.337 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.663 0.337 0.000
O80-O84 Delivery
0.663 0.337 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.662 0.338 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.661 0.339 0.000
L20-L30 Dermatitis and eczema
0.661 0.339 0.000
O75.9 Complication of labour and delivery, unspecified
0.661 0.339 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.661 0.339 0.000
O75.4 Other complications of obstetric surgery and procedures
0.661 0.339 0.000
O75.3 Other infection during labour
0.661 0.339 0.000
O75.1 Shock during or following labour and delivery
0.661 0.339 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.661 0.339 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.661 0.339 0.000
B65-B83 Helminthiases
0.661 0.339 0.000
B50-B64 Protozoal diseases
0.661 0.339 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.661 0.339 0.000
A80-A89 Viral infections of the central nervous system
0.661 0.339 0.000
A75-A79 Rickettsioses
0.661 0.339 0.000
A70-A74 Other diseases caused by chlamydiae
0.661 0.339 0.000
A65-A69 Other spirochaetal diseases
0.661 0.339 0.000
A20-A28 Certain zoonotic bacterial diseases
0.661 0.339 0.000
A15-A19 Tuberculosis
0.661 0.339 0.000
S80 Superficial injury of lower leg
0.660 0.340 0.000
S22.3 Fracture of rib
0.659 0.340 0.000
T98 Sequelae of other and unspecified effects of external causes
0.659 0.341 0.000
T95 Sequelae of burns, corrosions and frostbite
0.659 0.341 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.659 0.341 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.659 0.341 0.000
O42 Premature rupture of membranes
0.659 0.341 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.659 0.341 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.658 0.342 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.657 0.343 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.657 0.343 0.000
S64.4 Injury of digital nerve of other finger
0.657 0.343 0.000
R47-R49 Symptoms and signs involving speech and voice
0.657 0.343 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.656 0.344 0.000
O62.3 Precipitate labour
0.656 0.344 0.000
H34 Retinal vascular occlusions
0.656 0.344 0.000
H36.0 Diabetic retinopathy
0.656 0.344 0.000
I51.6 Cardiovascular disease, unspecified
0.655 0.345 0.000
I51.5 Myocardial degeneration
0.655 0.345 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.655 0.345 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.655 0.345 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.655 0.345 0.000
I51.0 Cardiac septal defect, acquired
0.655 0.345 0.000
R44.3 Hallucinations, unspecified
0.655 0.345 0.000
M79.10 Myalgia (Multiple sites)
0.655 0.345 0.000
H35.3 Degeneration of macula and posterior pole
0.655 0.345 0.000
M07 Psoriatic and enteropathic arthropathies
0.654 0.345 0.000
H55-H59 Other disorders of eye and adnexa
0.654 0.346 0.000
S01.8 Open wound of other parts of head
0.654 0.346 0.000
G20-G26 Extrapyramidal and movement disorders
0.654 0.346 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.653 0.347 0.000
T91.3 Sequelae of injury of spinal cord
0.653 0.347 0.000
I33 Acute and subacute endocarditis
0.653 0.347 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.651 0.349 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.650 0.350 0.000
S27.0 Traumatic pneumothorax
0.649 0.350 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.649 0.351 0.000
M65 Synovitis and tenosynovitis
0.648 0.351 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.649 0.351 0.000
M72.9 Fibroblastic disorder, unspecified
0.648 0.351 0.000
M72.8 Other fibroblastic disorders
0.648 0.351 0.000
M72.6 Necrotizing fasciitis
0.648 0.351 0.000
M72.5 Fasciitis, not elsewhere classified
0.648 0.351 0.000
M72.4 Pseudosarcomatous fibromatosis
0.648 0.351 0.000
M72.3 Nodular fasciitis
0.648 0.351 0.000
M72.1 Knuckle pads
0.648 0.351 0.000
L40-L45 Papulosquamous disorders
0.647 0.353 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.647 0.353 0.000
S60 Superficial injury of wrist and hand
0.647 0.353 0.000
R46 Symptoms and signs involving appearance and behaviour
0.647 0.353 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.645 0.355 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.644 0.356 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.643 0.357 0.000
Y35-Y36 Legal intervention and operations of war
0.643 0.357 0.000
Y10-Y34 Event of undetermined intent
0.643 0.357 0.000
Y00-Y09 Assault
0.643 0.357 0.000
X85-X99 Assault
0.643 0.357 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.643 0.357 0.000
X50-X57 Overexertion, travel and privation
0.643 0.357 0.000
X30-X39 Exposure to forces of nature
0.643 0.357 0.000
X20-X29 Contact with venomous animals and plants
0.643 0.357 0.000
X10-X19 Contact with heat and hot substances
0.643 0.357 0.000
X00-X09 Exposure to smoke, fire and flames
0.643 0.357 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.643 0.357 0.000
W75-W84 Other accidental threats to breathing
0.643 0.357 0.000
W65-W74 Accidental drowning and submersion
0.643 0.357 0.000
W50-W64 Exposure to animate mechanical forces
0.643 0.357 0.000
V98-V99 Other and unspecified transport accidents
0.643 0.357 0.000
V95-V97 Air and space transport accidents
0.643 0.357 0.000
V90-V94 Water transport accidents
0.643 0.357 0.000
V70-V79 Bus occupant injured in transport accident
0.643 0.357 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.643 0.357 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.643 0.357 0.000
V40-V49 Car occupant injured in transport accident
0.643 0.357 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.643 0.357 0.000
V01-V09 Pedestrian injured in transport accident
0.643 0.357 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.640 0.360 0.000
M54.37 Sciatica (Lumbosacral region)
0.640 0.360 0.000
S09.8 Other specified injuries of head
0.639 0.360 0.000
S09.7 Multiple injuries of head
0.639 0.360 0.000
S09.2 Traumatic rupture of ear drum
0.639 0.360 0.000
S09.1 Injury of muscle and tendon of head
0.639 0.360 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.639 0.360 0.000
M41 Scoliosis
0.639 0.361 0.000
S65 Injury of blood vessels at wrist and hand level
0.639 0.361 0.000
M47 Spondylosis
0.638 0.362 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.638 0.362 0.000
Y88 Sequelae of surgical and medical care as external cause
0.638 0.362 0.000
M79.5 Residual foreign body in soft tissue
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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