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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77959025
log Bayes Factor = 16.9241
Chromosome 8   position 128,761,169  (GRCh37) Explore rs77959025 on Ensembl!
Variant rs77959025 is part of Cluster X0081

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
Z92 Personal history of medical treatment
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
R07 Pain in throat and chest
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
Z85 Personal history of malignant neoplasm
0.994 0.006 0.000
R07.4 Chest pain, unspecified
0.993 0.007 0.000
I30-I52 Other forms of heart disease
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
Chapter II Neoplasms
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.986 0.014 0.000
Chapter VI Diseases of the nervous system
0.984 0.016 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.981 0.019 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.979 0.021 0.000
T81 Complications of procedures, not elsewhere classified
0.979 0.021 0.000
I44 Atrioventricular and left bundle-branch block
0.979 0.021 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.977 0.023 0.000
Chapter V Mental and behavioural disorders
0.975 0.025 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.975 0.025 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.975 0.025 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.973 0.027 0.000
T39.1 4-Aminophenol derivatives
0.950 0.050 0.000
I44.0 Atrioventricular block, first degree
0.949 0.051 0.000
R04 Haemorrhage from respiratory passages
0.948 0.052 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.947 0.053 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.946 0.054 0.000
R50-R69 General symptoms and signs
0.945 0.055 0.000
Z88.0 Personal history of allergy to penicillin
0.944 0.056 0.000
Z72 Problems related to lifestyle
0.942 0.058 0.000
R06 Abnormalities of breathing
0.933 0.067 0.000
C50-C50 Malignant neoplasm of breast
0.928 0.072 0.000
R63 Symptoms and signs concerning food and fluid intake
0.925 0.075 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.922 0.078 0.000
M50-M54 Other dorsopathies
0.921 0.079 0.000
S00-S09 Injuries to the head
0.916 0.084 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.914 0.086 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.911 0.089 0.000
R04.0 Epistaxis
0.908 0.092 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.907 0.093 0.000
R00 Abnormalities of heart beat
0.901 0.099 0.000
M40-M43 Deforming dorsopathies
0.901 0.099 0.000
I34 Nonrheumatic mitral valve disorders
0.901 0.099 0.000
G40-G47 Episodic and paroxysmal disorders
0.890 0.110 0.000
G57 Mononeuropathies of lower limb
0.890 0.110 0.000
R63.4 Abnormal weight loss
0.885 0.115 0.000
C50 Malignant neoplasm of breast
0.884 0.116 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.884 0.116 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.883 0.117 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.880 0.120 0.000
Z72.1 Alcohol use
0.879 0.121 0.000
I60-I69 Cerebrovascular diseases
0.873 0.127 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.873 0.127 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.872 0.128 0.000
G40 Epilepsy
0.868 0.132 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.868 0.132 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.867 0.133 0.000
M20-M25 Other joint disorders
0.864 0.136 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.863 0.137 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.862 0.138 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.861 0.139 0.000
R06.0 Dyspnoea
0.860 0.140 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.858 0.142 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.856 0.144 0.000
R00.2 Palpitations
0.854 0.146 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.849 0.151 0.000
G57.6 Lesion of plantar nerve
0.847 0.153 0.000
W20-W49 Exposure to inanimate mechanical forces
0.847 0.153 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.846 0.154 0.000
I44.7 Left bundle-branch block, unspecified
0.844 0.156 0.000
S20-S29 Injuries to the thorax
0.843 0.157 0.000
M45-M49 Spondylopathies
0.841 0.159 0.000
S01 Open wound of head
0.840 0.160 0.000
C64-C68 Malignant neoplasms of urinary tract
0.840 0.160 0.000
I35 Nonrheumatic aortic valve disorders
0.839 0.161 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.839 0.161 0.000
G40.9 Epilepsy, unspecified
0.839 0.161 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.838 0.161 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.838 0.162 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.836 0.163 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.834 0.166 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.832 0.168 0.000
G56 Mononeuropathies of upper limb
0.831 0.169 0.000
R63.0 Anorexia
0.829 0.171 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.829 0.171 0.000
Z74 Problems related to care-provider dependency
0.828 0.172 0.000
R56 Convulsions, not elsewhere classified
0.826 0.174 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.825 0.175 0.000
F17.1 Harmful use
0.824 0.176 0.000
Z90.1 Acquired absence of breast(s)
0.824 0.176 0.000
Z72.0 Tobacco use
0.823 0.177 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.822 0.178 0.000
F30-F39 Mood [affective] disorders
0.820 0.180 0.000
R52 Pain, not elsewhere classified
0.815 0.185 0.000
I45 Other conduction disorders
0.815 0.185 0.000
R02 Gangrene, not elsewhere classified
0.814 0.186 0.000
M70-M79 Other soft tissue disorders
0.813 0.187 0.000
Z92.3 Personal history of irradiation
0.812 0.188 0.000
I67 Other cerebrovascular diseases
0.811 0.189 0.000
Z42 Follow-up care involving plastic surgery
0.811 0.189 0.000
M51 Other intervertebral disk disorders
0.808 0.192 0.000
M86-M90 Other osteopathies
0.807 0.193 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.805 0.195 0.000
Chapter VIII Diseases of the ear and mastoid process
0.804 0.196 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.800 0.200 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.798 0.202 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.798 0.202 0.000
I34.1 Mitral (valve) prolapse
0.796 0.204 0.000
Z89 Acquired absence of limb
0.796 0.204 0.000
M43 Other deforming dorsopathies
0.795 0.205 0.000
I47 Paroxysmal tachycardia
0.792 0.208 0.000
Chapter XXII Codes for special purposes
0.792 0.208 0.000
Z85.6 Personal history of leukaemia
0.792 0.208 0.000
M20 Acquired deformities of fingers and toes
0.791 0.209 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.790 0.210 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.790 0.210 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.788 0.212 0.000
I42 Cardiomyopathy
0.788 0.212 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.787 0.213 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.787 0.213 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.787 0.213 0.000
R50 Fever of unknown origin
0.787 0.213 0.000
Z75 Problems related to medical facilities and other health care
0.786 0.214 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.786 0.214 0.000
M50 Cervical disk disorders
0.783 0.217 0.000
Z73 Problems related to life-management difficulty
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.783 0.217 0.000
T51 Toxic effect of alcohol
0.782 0.218 0.000
G51 Facial nerve disorders
0.782 0.218 0.000
V40-V49 Car occupant injured in transport accident
0.782 0.218 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.781 0.219 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.781 0.219 0.000
I38 Endocarditis, valve unspecified
0.780 0.220 0.000
D00-D09 In situ neoplasms
0.777 0.223 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.777 0.223 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.777 0.223 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.776 0.224 0.000
C50.4 Upper-outer quadrant of breast
0.775 0.225 0.000
S90-S99 Injuries to the ankle and foot
0.774 0.226 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.774 0.226 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.773 0.227 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.772 0.228 0.000
R06.4 Hyperventilation
0.771 0.228 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.771 0.229 0.000
M20.4 Other hammer toe(s) (acquired)
0.771 0.229 0.000
C15-C26 Malignant neoplasms of digestive organs
0.770 0.230 0.000
R55 Syncope and collapse
0.769 0.231 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.767 0.233 0.000
S06 Intracranial injury
0.767 0.233 0.000
S01.0 Open wound of scalp
0.766 0.233 0.000
Z63 Other problems related to primary support group, including family circumstances
0.766 0.234 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.766 0.234 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.763 0.237 0.000
C50.1 Central portion of breast
0.761 0.239 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.760 0.240 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.759 0.241 0.000
C50.5 Lower-outer quadrant of breast
0.759 0.241 0.000
S40-S49 Injuries to the shoulder and upper arm
0.758 0.242 0.000
C77.3 Axillary and upper limb lymph nodes
0.758 0.242 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.757 0.243 0.000
R20 Disturbances of skin sensation
0.756 0.244 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.755 0.245 0.000
D80-D89 Certain disorders involving the immune mechanism
0.755 0.245 0.000
T66-T78 Other and unspecified effects of external causes
0.753 0.247 0.000
I51 Complications and ill-defined descriptions of heart disease
0.753 0.247 0.000
F80-F89 Disorders of psychological development
0.753 0.247 0.000
M79.6 Pain in limb
0.753 0.247 0.000
I50 Heart failure
0.752 0.248 0.000
G56.1 Other lesions of median nerve
0.752 0.248 0.000
M05-M14 Inflammatory polyarthropathies
0.752 0.248 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.751 0.249 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.749 0.251 0.000
X60-X84 Intentional self-harm
0.747 0.253 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.747 0.253 0.000
I44.1 Atrioventricular block, second degree
0.747 0.253 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.745 0.255 0.000
I95 Hypotension
0.745 0.255 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.745 0.255 0.000
M41 Scoliosis
0.745 0.255 0.000
R06.5 Mouth breathing
0.744 0.256 0.000
I44.2 Atrioventricular block, complete
0.743 0.257 0.000
G90-G99 Other disorders of the nervous system
0.743 0.257 0.000
M91-M94 Chondropathies
0.742 0.257 0.000
R56.8 Other and unspecified convulsions
0.741 0.259 0.000
Z90.2 Acquired absence of lung [part of]
0.741 0.259 0.000
I34.0 Mitral (valve) insufficiency
0.740 0.260 0.000
T86 Failure and rejection of transplanted organs and tissues
0.740 0.260 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.738 0.262 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.737 0.263 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.731 0.268 0.000
Chapter XI Diseases of the digestive system
0.732 0.268 0.000
R07.2 Precordial pain
0.731 0.269 0.000
I63 Cerebral infarction
0.730 0.270 0.000
M51.2 Other specified intervertebral disk displacement
0.729 0.271 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.728 0.272 0.000
C50.2 Upper-inner quadrant of breast
0.728 0.272 0.000
C85.1 B-cell lymphoma, unspecified
0.727 0.273 0.000
W00-W19 Falls
0.727 0.273 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.726 0.274 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.725 0.275 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.725 0.275 0.000
R57 Shock, not elsewhere classified
0.724 0.276 0.000
M48 Other spondylopathies
0.724 0.276 0.000
T40.2 Other opioids
0.721 0.279 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.720 0.280 0.000
G70-G73 Diseases of myoneural junction and muscle
0.720 0.280 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.720 0.280 0.000
S80-S89 Injuries to the knee and lower leg
0.719 0.281 0.000
Z74.0 Reduced mobility
0.719 0.281 0.000
W29 Contact with other powered hand tools and household machinery
0.719 0.281 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.718 0.282 0.000
R00.1 Bradycardia, unspecified
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.716 0.284 0.000
Z92.9 Personal history of medical treatment, unspecified
0.715 0.285 0.000
Z92.8 Personal history of other medical treatment
0.715 0.285 0.000
Z92.5 Personal history of rehabilitation measures
0.715 0.285 0.000
Z92.0 Personal history of contraception
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
R07.1 Chest pain on breathing
0.714 0.286 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.713 0.286 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.712 0.288 0.000
C18 Malignant neoplasm of colon
0.712 0.288 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I33 Acute and subacute endocarditis
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
I30 Acute pericarditis
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.710 0.289 0.000
M00-M03 Infectious arthropathies
0.710 0.289 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.710 0.290 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.709 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.291 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.291 0.000
Y95 Nosocomial condition
0.709 0.291 0.000
S70-S79 Injuries to the hip and thigh
0.708 0.291 0.000
Z93 Artificial opening status
0.708 0.291 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.708 0.292 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.707 0.293 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
Y00-Y09 Assault
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X50-X57 Overexertion, travel and privation
0.707 0.293 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.293 0.000
V95-V97 Air and space transport accidents
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V80-V89 Other land transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.293 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.294 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.705 0.295 0.000
R52.1 Chronic intractable pain
0.705 0.295 0.000
Z30 Contraceptive management
0.704 0.296 0.000
R03.1 Nonspecific low blood-pressure reading
0.703 0.297 0.000
Z76 Persons encountering health services in other circumstances
0.703 0.297 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.703 0.297 0.000
I69 Sequelae of cerebrovascular disease
0.703 0.297 0.000
G58 Other mononeuropathies
0.702 0.298 0.000
M54 Dorsalgia
0.702 0.298 0.000
T81.9 Unspecified complication of procedure
0.702 0.298 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.702 0.298 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.702 0.298 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.702 0.298 0.000
I44.6 Other and unspecified fascicular block
0.702 0.298 0.000
I44.5 Left posterior fascicular block
0.702 0.298 0.000
I44.4 Left anterior fascicular block
0.702 0.298 0.000
I44.3 Other and unspecified atrioventricular block
0.702 0.298 0.000
K80 Cholelithiasis
0.701 0.299 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.301 0.000
F70-F79 Mental retardation
0.699 0.301 0.000
F60-F69 Disorders of adult personality and behaviour
0.699 0.301 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.699 0.301 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.699 0.301 0.000
T39.4 Antirheumatics, not elsewhere classified
0.699 0.301 0.000
T39.2 Pyrazolone derivatives
0.699 0.301 0.000
T39.0 Salicylates
0.699 0.301 0.000
M24 Other specific joint derangements
0.699 0.301 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.697 0.303 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.697 0.303 0.000
R04.2 Haemoptysis
0.697 0.303 0.000
R07.3 Other chest pain
0.697 0.303 0.000
G20-G26 Extrapyramidal and movement disorders
0.696 0.304 0.000
M43.1 Spondylolisthesis
0.696 0.304 0.000
F99-F99 Unspecified mental disorder
0.694 0.305 0.000
R07.0 Pain in throat
0.694 0.306 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.694 0.306 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.693 0.307 0.000
Z88.5 Personal history of allergy to narcotic agent
0.693 0.307 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.692 0.307 0.000
Y40 Systemic antibiotics
0.692 0.308 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.691 0.309 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.689 0.311 0.000
Z88.2 Personal history of allergy to sulphonamides
0.686 0.313 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.684 0.316 0.000
I67.9 Cerebrovascular disease, unspecified
0.683 0.317 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.683 0.317 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.682 0.318 0.000
I67.8 Other specified cerebrovascular diseases
0.682 0.318 0.000
I95.1 Orthostatic hypotension
0.682 0.318 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.682 0.318 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.681 0.319 0.000
S60-S69 Injuries to the wrist and hand
0.681 0.319 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.680 0.320 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.679 0.320 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.679 0.320 0.000
R04.1 Haemorrhage from throat
0.679 0.320 0.000
Z40 Prophylactic surgery
0.679 0.321 0.000
E65-E68 Obesity and other hyperalimentation
0.679 0.321 0.000
G54 Nerve root and plexus disorders
0.678 0.321 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.678 0.321 0.000
G52 Disorders of other cranial nerves
0.678 0.321 0.000
F10.1 Harmful use
0.678 0.322 0.000
Z60 Problems related to social environment
0.678 0.322 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.677 0.322 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.677 0.323 0.000
R62 Lack of expected normal physiological development
0.677 0.323 0.000
R64 Cachexia
0.677 0.323 0.000
R58 Haemorrhage, not elsewhere classified
0.677 0.323 0.000
Y48 Anaesthetics and therapeutic gases
0.676 0.324 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.676 0.324 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.676 0.324 0.000
T43.2 Other and unspecified antidepressants
0.676 0.324 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.676 0.324 0.000
Z72.9 Problem related to lifestyle, unspecified
0.675 0.325 0.000
Z72.8 Other problems related to lifestyle
0.675 0.325 0.000
Z72.6 Gambling and betting
0.675 0.325 0.000
Z72.5 High-risk sexual behaviour
0.675 0.325 0.000
Z72.4 Inappropriate diet and eating habits
0.675 0.325 0.000
Z72.3 Lack of physical exercise
0.675 0.325 0.000
Z72.2 Drug use
0.675 0.325 0.000
S20 Superficial injury of thorax
0.674 0.326 0.000
F33 Recurrent depressive disorder
0.673 0.327 0.000
C92 Myeloid leukaemia
0.673 0.327 0.000
Z49 Care involving dialysis
0.672 0.328 0.000
S00 Superficial injury of head
0.672 0.328 0.000
M65-M68 Disorders of synovium and tendon
0.672 0.328 0.000
R68 Other general symptoms and signs
0.672 0.328 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.671 0.329 0.000
I35.0 Aortic (valve) stenosis
0.670 0.330 0.000
T51.9 Alcohol, unspecified
0.669 0.331 0.000
S01.9 Open wound of head, part unspecified
0.669 0.331 0.000
R06.7 Sneezing
0.669 0.331 0.000
R06.6 Hiccough
0.669 0.331 0.000
R06.3 Periodic breathing
0.669 0.331 0.000
R06.1 Stridor
0.669 0.331 0.000
I67.1 Cerebral aneurysm, nonruptured
0.668 0.332 0.000
R06.2 Wheezing
0.668 0.332 0.000
Z87 Personal history of other diseases and conditions
0.668 0.332 0.000
I46 Cardiac arrest
0.667 0.333 0.000
I05-I09 Chronic rheumatic heart diseases
0.667 0.333 0.000
D86 Sarcoidosis
0.667 0.333 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.666 0.334 0.000
I31 Other diseases of pericardium
0.666 0.334 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.666 0.334 0.000
Z90.8 Acquired absence of other organs
0.665 0.335 0.000
S27 Injury of other and unspecified intrathoracic organs
0.665 0.335 0.000
H60-H62 Diseases of external ear
0.665 0.335 0.000
Z43 Attention to artificial openings
0.664 0.336 0.000
G30-G32 Other degenerative diseases of the nervous system
0.664 0.336 0.000
G51.0 Bell's palsy
0.664 0.336 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.663 0.337 0.000
R63.5 Abnormal weight gain
0.663 0.337 0.000
R63.3 Feeding difficulties and mismanagement
0.663 0.337 0.000
R63.2 Polyphagia
0.663 0.337 0.000
R63.1 Polydipsia
0.663 0.337 0.000
Z63.8 Other specified problems related to primary support group
0.663 0.337 0.000
I50.0 Congestive heart failure
0.662 0.338 0.000
C81 Hodgkin's disease
0.662 0.338 0.000
C51-C58 Malignant neoplasms of female genital organs
0.662 0.338 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.661 0.338 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.661 0.338 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.661 0.338 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.661 0.338 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.661 0.338 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.661 0.338 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.661 0.338 0.000
F11 Mental and behavioural disorders due to use of opioids
0.661 0.338 0.000
R20.2 Paraesthesia of skin
0.661 0.339 0.000
I45.2 Bifascicular block
0.661 0.339 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.661 0.339 0.000
M53 Other dorsopathies, not elsewhere classified
0.660 0.340 0.000
T82.1 Mechanical complication of cardiac electronic device
0.660 0.340 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.660 0.340 0.000
M21 Other acquired deformities of limbs
0.660 0.340 0.000
F30 Manic episode
0.660 0.340 0.000
I47.2 Ventricular tachycardia
0.660 0.340 0.000
Z48 Other surgical follow-up care
0.659 0.341 0.000
F41 Other anxiety disorders
0.659 0.341 0.000
C18.9 Colon, unspecified
0.659 0.341 0.000
R60 Oedema, not elsewhere classified
0.658 0.341 0.000
S08 Traumatic amputation of part of head
0.657 0.343 0.000
S07 Crushing injury of head
0.657 0.343 0.000
S05 Injury of eye and orbit
0.657 0.343 0.000
S04 Injury of cranial nerves
0.657 0.343 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.657 0.343 0.000
I51.7 Cardiomegaly
0.656 0.344 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.655 0.344 0.000
C95 Leukaemia of unspecified cell type
0.655 0.344 0.000
C94 Other leukaemias of specified cell type
0.655 0.344 0.000
C93 Monocytic leukaemia
0.655 0.344 0.000
C88 Malignant immunoproliferative diseases
0.655 0.344 0.000
C86 Other specified types of T/NK-cell lymphoma
0.655 0.344 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.655 0.344 0.000
H65-H75 Diseases of middle ear and mastoid
0.656 0.344 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.655 0.345 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.655 0.345 0.000
C83.3 Large cell (diffuse)
0.655 0.345 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.655 0.345 0.000
M34 Systemic sclerosis
0.655 0.345 0.000
T51.0 Ethanol
0.654 0.346 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.653 0.347 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.653 0.347 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.653 0.347 0.000
T82.3 Mechanical complication of other vascular grafts
0.653 0.347 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.653 0.347 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.653 0.347 0.000
D69 Purpura and other haemorrhagic conditions
0.653 0.347 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.653 0.347 0.000
R50.9 Fever, unspecified
0.653 0.347 0.000
Z41 Procedures for purposes other than remedying health state
0.652 0.348 0.000
M79.69 Pain in limb (Site unspecified)
0.651 0.349 0.000
Y83.5 Amputation of limb(s)
0.651 0.349 0.000
Y83.9 Surgical procedure, unspecified
0.651 0.349 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.650 0.350 0.000
G57.8 Other mononeuropathies of lower limb
0.650 0.350 0.000
I35.9 Aortic valve disorder, unspecified
0.650 0.350 0.000
X58 Exposure to other specified factors
0.649 0.351 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.649 0.351 0.000
Y83.6 Removal of other organ (partial) (total)
0.648 0.352 0.000
C78.0 Secondary malignant neoplasm of lung
0.648 0.352 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.647 0.352 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.647 0.353 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.647 0.353 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.646 0.354 0.000
M42 Spinal osteochondrosis
0.646 0.354 0.000
M40 Kyphosis and lordosis
0.646 0.354 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.646 0.354 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.646 0.354 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.646 0.354 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.646 0.354 0.000
M80-M85 Disorders of bone density and structure
0.646 0.354 0.000
W22 Striking against or struck by other objects
0.645 0.355 0.000
Y83.3 Surgical operation with formation of external stoma
0.644 0.356 0.000
S29 Other and unspecified injuries of thorax
0.644 0.356 0.000
M25 Other joint disorders, not elsewhere classified
0.644 0.356 0.000
C80 Malignant neoplasm without specification of site
0.643 0.357 0.000
E10-E14 Diabetes mellitus
0.643 0.357 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.643 0.357 0.000
I62 Other nontraumatic intracranial haemorrhage
0.641 0.359 0.000
M48.0 Spinal stenosis
0.641 0.359 0.000
R54 Senility
0.640 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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