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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77960981
log Bayes Factor = 12.5233
Chromosome 3   position 35,874,989  (GRCh37) Explore rs77960981 on Ensembl!
Variant rs77960981 is part of Cluster X0133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
G40-G47 Episodic and paroxysmal disorders
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
G40 Epilepsy
0.988 0.012 0.000
M20-M25 Other joint disorders
0.984 0.016 0.000
G40.9 Epilepsy, unspecified
0.980 0.020 0.000
E70-E90 Metabolic disorders
0.979 0.021 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.979 0.021 0.000
E00-E07 Disorders of thyroid gland
0.978 0.022 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.978 0.022 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.976 0.024 0.000
M80-M85 Disorders of bone density and structure
0.972 0.028 0.000
E04 Other non-toxic goitre
0.971 0.029 0.000
M25 Other joint disorders, not elsewhere classified
0.971 0.029 0.000
W00-W19 Falls
0.970 0.030 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.967 0.033 0.000
M50-M54 Other dorsopathies
0.964 0.036 0.000
M25.5 Pain in joint
0.964 0.036 0.000
R47-R49 Symptoms and signs involving speech and voice
0.963 0.037 0.000
G43 Migraine
0.958 0.042 0.000
Y95 Nosocomial condition
0.957 0.043 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.956 0.044 0.000
W19 Unspecified fall
0.951 0.049 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.949 0.051 0.000
T93 Sequelae of injuries of lower limb
0.948 0.052 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.945 0.055 0.000
M45-M49 Spondylopathies
0.945 0.055 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.944 0.056 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.939 0.061 0.000
Chapter II Neoplasms
0.939 0.061 0.000
E89.0 Postprocedural hypothyroidism
0.938 0.062 0.000
G43.9 Migraine, unspecified
0.936 0.064 0.000
E04.2 Non-toxic multinodular goitre
0.935 0.065 0.000
E78.5 Hyperlipidaemia, unspecified
0.921 0.079 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.918 0.082 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.914 0.086 0.000
M65-M68 Disorders of synovium and tendon
0.910 0.090 0.000
Chapter XXII Codes for special purposes
0.908 0.091 0.000
R47 Speech disturbances, not elsewhere classified
0.908 0.092 0.000
S40-S49 Injuries to the shoulder and upper arm
0.904 0.096 0.000
W19.9 Unspecified place
0.903 0.097 0.000
M84 Disorders of continuity of bone
0.901 0.099 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.898 0.102 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.895 0.105 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.893 0.107 0.000
Chapter V Mental and behavioural disorders
0.892 0.108 0.000
E04.1 Non-toxic single thyroid nodule
0.892 0.108 0.000
E40-E46 Malnutrition
0.891 0.109 0.000
M35 Other systemic involvement of connective tissue
0.884 0.116 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.878 0.122 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.878 0.122 0.000
R29.6 Tendency to fall, not elsewhere classified
0.876 0.124 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.872 0.128 0.000
M54 Dorsalgia
0.872 0.128 0.000
M25.57 Pain in joint (Ankle and foot)
0.866 0.134 0.000
V10-V19 Pedal cyclist injured in transport accident
0.858 0.142 0.000
R26 Abnormalities of gait and mobility
0.858 0.142 0.000
R47.8 Other and unspecified speech disturbances
0.857 0.143 0.000
G81 Hemiplegia
0.854 0.146 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.852 0.148 0.000
G30-G32 Other degenerative diseases of the nervous system
0.851 0.149 0.000
E04.9 Non-toxic goitre, unspecified
0.844 0.156 0.000
G82 Paraplegia and tetraplegia
0.843 0.157 0.000
R49 Voice disturbances
0.841 0.159 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.839 0.161 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.839 0.161 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.838 0.162 0.000
M40-M43 Deforming dorsopathies
0.837 0.163 0.000
T66-T78 Other and unspecified effects of external causes
0.837 0.163 0.000
R73 Elevated blood glucose level
0.835 0.165 0.000
R50-R69 General symptoms and signs
0.835 0.165 0.000
M48 Other spondylopathies
0.834 0.166 0.000
M50 Cervical disk disorders
0.834 0.166 0.000
C80 Malignant neoplasm without specification of site
0.833 0.167 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.832 0.168 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.831 0.169 0.000
T93.2 Sequelae of other fractures of lower limb
0.831 0.169 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.827 0.172 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.827 0.173 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.826 0.174 0.000
M65 Synovitis and tenosynovitis
0.824 0.176 0.000
C77.2 Intra-abdominal lymph nodes
0.824 0.176 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.822 0.178 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.821 0.179 0.000
E78.2 Mixed hyperlipidaemia
0.818 0.182 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.818 0.182 0.000
M51 Other intervertebral disk disorders
0.817 0.183 0.000
M25.53 Pain in joint (Forearm)
0.816 0.184 0.000
M85 Other disorders of bone density and structure
0.815 0.184 0.000
E46 Unspecified protein-energy malnutrition
0.815 0.185 0.000
S80-S89 Injuries to the knee and lower leg
0.815 0.185 0.000
M35.0 Sicca syndrome [Sjogren]
0.814 0.186 0.000
W19.4 Street and highway
0.809 0.191 0.000
T93.0 Sequelae of open wound of lower limb
0.806 0.194 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.804 0.196 0.000
D60-D64 Aplastic and other anaemias
0.804 0.196 0.000
M25.8 Other specified joint disorders
0.802 0.198 0.000
W19.2 School, other institution and public administrative area
0.802 0.198 0.000
E78.8 Other disorders of lipoprotein metabolism
0.801 0.199 0.000
G80 Infantile cerebral palsy
0.799 0.201 0.000
M54.3 Sciatica
0.799 0.201 0.000
T17 Foreign body in respiratory tract
0.799 0.201 0.000
M81 Osteoporosis without pathological fracture
0.798 0.202 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
M21 Other acquired deformities of limbs
0.794 0.206 0.000
R73.9 Hyperglycaemia, unspecified
0.794 0.206 0.000
T92 Sequelae of injuries of upper limb
0.793 0.207 0.000
M25.52 Pain in joint (Upper arm)
0.789 0.211 0.000
G20-G26 Extrapyramidal and movement disorders
0.788 0.212 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.787 0.213 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.786 0.214 0.000
E88 Other metabolic disorders
0.784 0.216 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.782 0.218 0.000
G47 Sleep disorders
0.781 0.219 0.000
R59 Enlarged lymph nodes
0.780 0.220 0.000
C77.1 Intrathoracic lymph nodes
0.780 0.220 0.000
M50.2 Other cervical disk displacement
0.779 0.221 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.778 0.222 0.000
M47 Spondylosis
0.777 0.223 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.777 0.223 0.000
G81.9 Hemiplegia, unspecified
0.773 0.227 0.000
C77.0 Lymph nodes of head, face and neck
0.773 0.227 0.000
M25.59 Pain in joint (Site unspecified)
0.772 0.228 0.000
R21 Rash and other nonspecific skin eruption
0.771 0.229 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.771 0.229 0.000
G70-G73 Diseases of myoneural junction and muscle
0.770 0.230 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.769 0.231 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.767 0.233 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.764 0.236 0.000
R20 Disturbances of skin sensation
0.764 0.236 0.000
M60-M63 Disorders of muscles
0.763 0.236 0.000
M45 Ankylosing spondylitis
0.763 0.237 0.000
T91 Sequelae of injuries of neck and trunk
0.763 0.237 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.763 0.237 0.000
R47.0 Dysphasia and aphasia
0.761 0.239 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.761 0.239 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.760 0.240 0.000
T00-T07 Injuries involving multiple body regions
0.760 0.240 0.000
S00-S09 Injuries to the head
0.760 0.240 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.759 0.241 0.000
G83 Other paralytic syndromes
0.757 0.243 0.000
T79-T79 Certain early complications of trauma
0.757 0.243 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.756 0.243 0.000
G90-G99 Other disorders of the nervous system
0.756 0.244 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.756 0.244 0.000
M24 Other specific joint derangements
0.755 0.245 0.000
F80-F89 Disorders of psychological development
0.755 0.245 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.754 0.246 0.000
C64-C68 Malignant neoplasms of urinary tract
0.753 0.247 0.000
V40-V49 Car occupant injured in transport accident
0.752 0.248 0.000
E06 Thyroiditis
0.750 0.250 0.000
U88 Agent resistant to multiple antibiotics
0.750 0.250 0.000
M80 Osteoporosis with pathological fracture
0.748 0.252 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.747 0.253 0.000
R49.0 Dysphonia
0.747 0.253 0.000
R26.3 Immobility
0.744 0.256 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.744 0.256 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.743 0.257 0.000
E07 Other disorders of thyroid
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.742 0.258 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.741 0.259 0.000
M86-M90 Other osteopathies
0.740 0.259 0.000
W50-W64 Exposure to animate mechanical forces
0.740 0.260 0.000
M48.0 Spinal stenosis
0.740 0.260 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.740 0.260 0.000
M84.0 Malunion of fracture
0.740 0.260 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.738 0.262 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.738 0.262 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.737 0.263 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.737 0.263 0.000
M00-M03 Infectious arthropathies
0.737 0.263 0.000
D70 Agranulocytosis
0.736 0.264 0.000
V20-V29 Motorcycle rider injured in transport accident
0.735 0.265 0.000
Y57 Other and unspecified drugs and medicaments
0.735 0.265 0.000
C79 Secondary malignant neoplasm of other sites
0.734 0.266 0.000
C51-C58 Malignant neoplasms of female genital organs
0.734 0.266 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.733 0.267 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.733 0.267 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.732 0.268 0.000
F60-F69 Disorders of adult personality and behaviour
0.731 0.269 0.000
S40 Superficial injury of shoulder and upper arm
0.731 0.269 0.000
M51.2 Other specified intervertebral disk displacement
0.731 0.269 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.731 0.269 0.000
W07 Fall involving chair
0.731 0.269 0.000
W06 Fall involving bed
0.729 0.271 0.000
M25.50 Pain in joint (Multiple sites)
0.728 0.272 0.000
R23 Other skin changes
0.728 0.272 0.000
T17.2 Foreign body in pharynx
0.727 0.273 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.726 0.274 0.000
G57 Mononeuropathies of lower limb
0.725 0.274 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.725 0.275 0.000
M25.3 Other instability of joint
0.725 0.275 0.000
M54.1 Radiculopathy
0.724 0.276 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.722 0.278 0.000
C77.4 Inguinal and lower limb lymph nodes
0.721 0.279 0.000
X50-X57 Overexertion, travel and privation
0.721 0.279 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.721 0.279 0.000
M46 Other inflammatory spondylopathies
0.720 0.279 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.720 0.280 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.719 0.281 0.000
R60 Oedema, not elsewhere classified
0.718 0.282 0.000
M25.0 Haemarthrosis
0.717 0.283 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
G82.4 Spastic tetraplegia
0.716 0.284 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.284 0.000
M41 Scoliosis
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
M66 Spontaneous rupture of synovium and tendon
0.715 0.285 0.000
G41 Status epilepticus
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
T98 Sequelae of other and unspecified effects of external causes
0.710 0.289 0.000
M82 Osteoporosis in diseases classified elsewhere
0.709 0.291 0.000
G40.8 Other epilepsy
0.708 0.291 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.708 0.291 0.000
G40.5 Special epileptic syndromes
0.708 0.291 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.708 0.291 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.708 0.291 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
D64 Other anaemias
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.706 0.294 0.000
M33 Dermatopolymyositis
0.706 0.294 0.000
M32 Systemic lupus erythematosus
0.706 0.294 0.000
M30 Polyarteritis nodosa and related conditions
0.706 0.294 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.705 0.295 0.000
E73 Lactose intolerance
0.705 0.295 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.704 0.296 0.000
U89 Agent resistant to other and unspecified antibiotics
0.704 0.296 0.000
M85.8 Other specified disorders of bone density and structure
0.703 0.297 0.000
E89.2 Postprocedural hypoparathyroidism
0.703 0.297 0.000
E85 Amyloidosis
0.702 0.298 0.000
E84 Cystic fibrosis
0.702 0.298 0.000
E79 Disorders of purine and pyrimidine metabolism
0.702 0.298 0.000
E77 Disorders of glycoprotein metabolism
0.702 0.298 0.000
E76 Disorders of glycosaminoglycan metabolism
0.702 0.298 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.702 0.298 0.000
E74 Other disorders of carbohydrate metabolism
0.702 0.298 0.000
E72 Other disorders of amino-acid metabolism
0.702 0.298 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.702 0.298 0.000
E70 Disorders of aromatic amino-acid metabolism
0.702 0.298 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.702 0.298 0.000
D62 Acute posthaemorrhagic anaemia
0.702 0.298 0.000
T95 Sequelae of burns, corrosions and frostbite
0.702 0.298 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.702 0.298 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.702 0.298 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.701 0.299 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.701 0.299 0.000
E00 Congenital iodine-deficiency syndrome
0.701 0.299 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.701 0.299 0.000
M25.9 Joint disorder, unspecified
0.701 0.299 0.000
D69 Purpura and other haemorrhagic conditions
0.700 0.300 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.700 0.300 0.000
Y98 Lifestyle-related condition
0.700 0.300 0.000
Y97 Environmental-pollution-related condition
0.700 0.300 0.000
Y96 Work-related condition
0.700 0.300 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.698 0.301 0.000
M83 Adult osteomalacia
0.697 0.303 0.000
R76 Other abnormal immunological findings in serum
0.697 0.303 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.696 0.304 0.000
E04.8 Other specified non-toxic goitre
0.696 0.304 0.000
E04.0 Non-toxic diffuse goitre
0.696 0.304 0.000
W13 Fall from, out of or through building or structure
0.696 0.304 0.000
R25 Abnormal involuntary movements
0.696 0.304 0.000
M25.2 Flail joint
0.696 0.304 0.000
M25.1 Fistula of joint
0.696 0.304 0.000
W17 Other fall from one level to another
0.695 0.304 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.695 0.304 0.000
W15 Fall from cliff
0.695 0.304 0.000
W14 Fall from tree
0.695 0.304 0.000
W12 Fall on and from scaffolding
0.695 0.304 0.000
W11 Fall on and from ladder
0.695 0.304 0.000
W09 Fall involving playground equipment
0.695 0.304 0.000
W08 Fall involving other furniture
0.695 0.304 0.000
W05 Fall involving wheelchair
0.695 0.304 0.000
W04 Fall while being carried or supported by other persons
0.695 0.304 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.695 0.304 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.695 0.304 0.000
W00 Fall on same level involving ice and snow
0.695 0.304 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.695 0.304 0.000
R45 Symptoms and signs involving emotional state
0.695 0.305 0.000
T14 Injury of unspecified body region
0.694 0.306 0.000
C80.9 Malignant neoplasm, unspecified
0.694 0.306 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.693 0.307 0.000
T39.1 4-Aminophenol derivatives
0.692 0.308 0.000
R30-R39 Symptoms and signs involving the urinary system
0.692 0.308 0.000
M25.58 Pain in joint (Other)
0.691 0.309 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.690 0.309 0.000
T18 Foreign body in alimentary tract
0.690 0.309 0.000
Y86 Sequelae of other accidents
0.690 0.310 0.000
D50-D53 Nutritional anaemias
0.690 0.310 0.000
R32 Unspecified urinary incontinence
0.690 0.310 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.689 0.310 0.000
S09 Other and unspecified injuries of head
0.688 0.312 0.000
R56 Convulsions, not elsewhere classified
0.687 0.313 0.000
G43.8 Other migraine
0.687 0.313 0.000
G43.3 Complicated migraine
0.687 0.313 0.000
G43.2 Status migrainosus
0.687 0.313 0.000
G43.0 Migraine without aura [common migraine]
0.687 0.313 0.000
M47.8 Other spondylosis
0.686 0.314 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.685 0.315 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.685 0.315 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.685 0.315 0.000
E89.5 Postprocedural testicular hypofunction
0.685 0.315 0.000
E89.4 Postprocedural ovarian failure
0.685 0.315 0.000
E89.1 Postprocedural hypoinsulinaemia
0.685 0.315 0.000
E89.3 Postprocedural hypopituitarism
0.685 0.315 0.000
G54 Nerve root and plexus disorders
0.684 0.315 0.000
Q80-Q89 Other congenital malformations
0.684 0.315 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.683 0.317 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.682 0.318 0.000
W19.8 Other specified place
0.682 0.318 0.000
W19.5 Trade and service area
0.682 0.318 0.000
W19.0 Home
0.682 0.318 0.000
W19.7 Farm
0.682 0.318 0.000
W19.6 Industrial and construction area
0.682 0.318 0.000
W19.3 Sports and athletics area
0.682 0.318 0.000
W19.1 Residential institution
0.682 0.318 0.000
R59.9 Enlarged lymph nodes, unspecified
0.681 0.319 0.000
M54.39 Sciatica (Site unspecified)
0.680 0.320 0.000
C77.5 Intrapelvic lymph nodes
0.680 0.320 0.000
R29.4 Clicking hip
0.680 0.320 0.000
R29.3 Abnormal posture
0.680 0.320 0.000
R29.2 Abnormal reflex
0.680 0.320 0.000
R29.1 Meningismus
0.680 0.320 0.000
R29.0 Tetany
0.680 0.320 0.000
M70-M79 Other soft tissue disorders
0.680 0.320 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.679 0.320 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.679 0.320 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.679 0.320 0.000
T93.1 Sequelae of fracture of femur
0.679 0.320 0.000
G80.9 Infantile cerebral palsy, unspecified
0.679 0.321 0.000
T90 Sequelae of injuries of head
0.678 0.322 0.000
E78.6 Lipoprotein deficiency
0.678 0.322 0.000
E78.4 Other hyperlipidaemia
0.678 0.322 0.000
E78.3 Hyperchylomicronaemia
0.678 0.322 0.000
E78.1 Pure hyperglyceridaemia
0.678 0.322 0.000
M49 Spondylopathies in diseases classified elsewhere
0.677 0.322 0.000
M23 Internal derangement of knee
0.677 0.323 0.000
D55-D59 Haemolytic anaemias
0.677 0.323 0.000
M54.4 Lumbago with sciatica
0.676 0.324 0.000
S80 Superficial injury of lower leg
0.676 0.324 0.000
W18 Other fall on same level
0.675 0.325 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.674 0.326 0.000
R51 Headache
0.673 0.327 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.673 0.327 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.673 0.327 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.673 0.327 0.000
T68 Hypothermia
0.672 0.328 0.000
M50.0 Cervical disk disorder with myelopathy
0.671 0.329 0.000
T78 Adverse effects, not elsewhere classified
0.671 0.329 0.000
R41.0 Disorientation, unspecified
0.670 0.330 0.000
R27 Other lack of coordination
0.669 0.330 0.000
V18.0 Driver injured in nontraffic accident
0.669 0.331 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.669 0.331 0.000
E65-E68 Obesity and other hyperalimentation
0.669 0.331 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.668 0.331 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.668 0.332 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.667 0.333 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.667 0.333 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.667 0.333 0.000
M53 Other dorsopathies, not elsewhere classified
0.667 0.333 0.000
S41 Open wound of shoulder and upper arm
0.666 0.334 0.000
C45 Mesothelioma
0.665 0.335 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.665 0.335 0.000
M25.54 Pain in joint (Hand)
0.665 0.335 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.664 0.336 0.000
F20 Schizophrenia
0.662 0.338 0.000
M54.37 Sciatica (Lumbosacral region)
0.662 0.338 0.000
R63 Symptoms and signs concerning food and fluid intake
0.662 0.338 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.662 0.338 0.000
W20-W49 Exposure to inanimate mechanical forces
0.662 0.338 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.661 0.338 0.000
M34 Systemic sclerosis
0.661 0.338 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.661 0.339 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.661 0.339 0.000
R59.1 Generalised enlarged lymph nodes
0.660 0.340 0.000
Q50-Q56 Congenital malformations of genital organs
0.659 0.341 0.000
S42 Fracture of shoulder and upper arm
0.659 0.341 0.000
G82.5 Tetraplegia, unspecified
0.658 0.341 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.658 0.342 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.658 0.342 0.000
R20.2 Paraesthesia of skin
0.658 0.342 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.655 0.345 0.000
G52 Disorders of other cranial nerves
0.655 0.345 0.000
R60.0 Localised oedema
0.655 0.345 0.000
M22 Disorders of patella
0.655 0.345 0.000
E86 Volume depletion
0.654 0.346 0.000
G95 Other diseases of spinal cord
0.654 0.346 0.000
C67 Malignant neoplasm of bladder
0.653 0.347 0.000
R54 Senility
0.653 0.347 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.652 0.348 0.000
M67 Other disorders of synovium and tendon
0.652 0.348 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.651 0.349 0.000
W10 Fall on and from stairs and steps
0.650 0.350 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.649 0.350 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.649 0.351 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.649 0.351 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.649 0.351 0.000
S48 Traumatic amputation of shoulder and upper arm
0.648 0.352 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.648 0.352 0.000
S44 Injury of nerves at shoulder and upper arm level
0.648 0.352 0.000
S47 Crushing injury of shoulder and upper arm
0.648 0.352 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.648 0.352 0.000
C73 Malignant neoplasm of thyroid gland
0.648 0.352 0.000
D73 Diseases of spleen
0.647 0.353 0.000
D48.1 Connective and other soft tissue
0.647 0.353 0.000
M25.84 Other specified joint disorders (Hand)
0.646 0.354 0.000
M84.9 Disorder of continuity of bone, unspecified
0.646 0.354 0.000
M84.8 Other disorders of continuity of bone
0.646 0.354 0.000
M84.4 Pathological fracture, not elsewhere classified
0.646 0.354 0.000
M84.3 Stress fracture, not elsewhere classified
0.646 0.354 0.000
M84.2 Delayed union of fracture
0.646 0.354 0.000
T87 Complications peculiar to reattachment and amputation
0.646 0.354 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.645 0.355 0.000
X60-X84 Intentional self-harm
0.644 0.356 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.644 0.356 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.644 0.356 0.000
R77 Other abnormalities of plasma proteins
0.644 0.356 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.644 0.356 0.000
R71 Abnormality of red blood cells
0.644 0.356 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.644 0.356 0.000
M51.9 Intervertebral disk disorder, unspecified
0.643 0.357 0.000
C56 Malignant neoplasm of ovary
0.643 0.357 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.642 0.358 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.641 0.359 0.000
R57 Shock, not elsewhere classified
0.641 0.359 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.641 0.359 0.000
M54.5 Low back pain
0.641 0.359 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.641 0.359 0.000
T19 Foreign body in genito-urinary tract
0.640 0.359 0.000
T15 Foreign body on external eye
0.640 0.359 0.000
T16 Foreign body in ear
0.640 0.359 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.640 0.360 0.000
F70-F79 Mental retardation
0.640 0.360 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.638 0.361 0.000
E45 Retarded development following protein-energy malnutrition
0.638 0.361 0.000
E43 Unspecified severe protein-energy malnutrition
0.638 0.361 0.000
E42 Marasmic kwashiorkor
0.638 0.361 0.000
E41 Nutritional marasmus
0.638 0.361 0.000
E40 Kwashiorkor
0.638 0.361 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.638 0.362 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.637 0.363 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.636 0.364 0.000
D64.9 Anaemia, unspecified
0.636 0.364 0.000
S09.9 Unspecified injury of head
0.636 0.364 0.000
M65.8 Other synovitis and tenosynovitis
0.635 0.365 0.000
M54.36 Sciatica (Lumbar region)
0.635 0.365 0.000
M81.2 Osteoporosis of disuse
0.635 0.365 0.000
R58 Haemorrhage, not elsewhere classified
0.635 0.365 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.634 0.366 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.634 0.366 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.634 0.366 0.000
M35.8 Other specified systemic involvement of connective tissue
0.634 0.366 0.000
M35.7 Hypermobility syndrome
0.634 0.366 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.634 0.366 0.000
M35.5 Multifocal fibrosclerosis
0.634 0.366 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.634 0.366 0.000
M35.2 Behcet's disease
0.634 0.366 0.000
M35.1 Other overlap syndromes
0.634 0.366 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.634 0.366 0.000
S83.2 Tear of meniscus, current
0.633 0.367 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.633 0.367 0.000
R74 Abnormal serum enzyme levels
0.633 0.367 0.000
G51 Facial nerve disorders
0.633 0.367 0.000
M84.06 Malunion of fracture (Lower leg)
0.633 0.367 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.631 0.369 0.000
Y57.9 Drug or medicament, unspecified
0.630 0.370 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.629 0.370 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.629 0.371 0.000
R63.0 Anorexia
0.629 0.371 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.629 0.371 0.000
Q35-Q37 Cleft lip and cleft palate
0.629 0.371 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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