TreeWAS – Variant ID: rs78141093

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
C60-C63 Malignant neoplasms of male genital organs	0.998	0.002
Chapter X Diseases of the respiratory system	0.998	0.002
Chapter VII Diseases of the eye and adnexa	0.997	0.003
C61 Malignant neoplasm of prostate	0.997	0.003
Chapter XXI Factors influencing health status and contact with health services	0.995	0.005
J40-J47 Chronic lower respiratory diseases	0.992	0.008
J44 Other chronic obstructive pulmonary disease	0.990	0.010
M20-M25 Other joint disorders	0.986	0.014
Z40-Z54 Persons encountering health services for specific procedures and health care	0.982	0.018
M45-M49 Spondylopathies	0.971	0.029
J44.9 Chronic obstructive pulmonary disease, unspecified	0.970	0.030
J80-J84 Other respiratory diseases principally affecting the interstitium	0.965	0.035
M50-M54 Other dorsopathies	0.958	0.042
Chapter V Mental and behavioural disorders	0.957	0.043
M25 Other joint disorders, not elsewhere classified	0.956	0.044
Z50 Care involving use of rehabilitation procedures	0.953	0.047
M47 Spondylosis	0.952	0.048
C64-C68 Malignant neoplasms of urinary tract	0.946	0.054
D37-D48 Neoplasms of uncertain or unknown behaviour	0.946	0.054
S00-S09 Injuries to the head	0.944	0.056
Chapter VI Diseases of the nervous system	0.942	0.058
M25.7 Osteophyte	0.937	0.063
J84 Other interstitial pulmonary diseases	0.930	0.070
Z50.1 Other physical therapy	0.929	0.071
Chapter XIV Diseases of the genitourinary system	0.929	0.071
Chapter IX Diseases of the circulatory system	0.926	0.074
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.923	0.077
N40-N51 Diseases of male genital organs	0.922	0.078
S70-S79 Injuries to the hip and thigh	0.921	0.079
M47.9 Spondylosis, unspecified	0.921	0.079
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.919	0.081
H40-H42 Glaucoma	0.919	0.081
I10-I15 Hypertensive diseases	0.917	0.083
N40 Hyperplasia of prostate	0.916	0.084
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.912	0.088
Z53 Persons encountering health services for specifie procedures, not carried out	0.912	0.088
I10 Essential (primary) hypertension	0.909	0.091
J84.1 Other interstitial pulmonary diseases with fibrosis	0.909	0.091
S60-S69 Injuries to the wrist and hand	0.907	0.093
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.904	0.096
J20-J22 Other acute lower respiratory infections	0.902	0.098
Z53.0 Procedure not carried out because of contraindication	0.899	0.101
C67 Malignant neoplasm of bladder	0.893	0.107
H43-H45 Disorders of vitreous body and globe	0.888	0.112
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.887	0.113
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.885	0.115
I60-I69 Cerebrovascular diseases	0.884	0.116
G90-G99 Other disorders of the nervous system	0.882	0.118
M54 Dorsalgia	0.882	0.118
M23 Internal derangement of knee	0.880	0.120
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.875	0.125
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.874	0.126
M25.77 Osteophyte (Ankle and foot)	0.874	0.126
Chapter VIII Diseases of the ear and mastoid process	0.872	0.128
D00-D09 In situ neoplasms	0.869	0.131
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.867	0.133
Chapter XX External causes of morbidity and mortality	0.866	0.134
N17-N19 Renal failure	0.865	0.135
Z70-Z76 Persons encountering health services in other circumstances	0.863	0.137
H40 Glaucoma	0.862	0.138
M47.8 Other spondylosis	0.860	0.140
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.859	0.141
Z00-Z13 Persons encountering health services for examination and investigation	0.857	0.143
C62 Malignant neoplasm of testis	0.856	0.144
S72 Fracture of femur	0.852	0.148
H55-H59 Other disorders of eye and adnexa	0.850	0.150
D46 Myelodysplastic syndromes	0.848	0.152
F30-F39 Mood [affective] disorders	0.846	0.154
M47.96 Spondylosis, unspecified (Lumbar region)	0.842	0.158
S64 Injury of nerves at wrist and hand level	0.842	0.158
N48 Other disorders of penis	0.839	0.161
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.836	0.164
J22 Unspecified acute lower respiratory infection	0.833	0.167
M25.76 Osteophyte (Lower leg)	0.833	0.167
Z02 Examination and encounter for administrative purposes	0.828	0.172
M50 Cervical disk disorders	0.827	0.173
R26 Abnormalities of gait and mobility	0.827	0.173
S50-S59 Injuries to the elbow and forearm	0.826	0.174
H43 Disorders of vitreous body	0.824	0.176
H40.9 Glaucoma, unspecified	0.824	0.176
M47.92 Spondylosis, unspecified (Cervical region)	0.824	0.176
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.822	0.178
S80-S89 Injuries to the knee and lower leg	0.821	0.179
M65-M68 Disorders of synovium and tendon	0.820	0.180
S01 Open wound of head	0.817	0.183
H18 Other disorders of cornea	0.816	0.184
I62 Other nontraumatic intracranial haemorrhage	0.815	0.185
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.815	0.185
G20-G26 Extrapyramidal and movement disorders	0.814	0.186
R25 Abnormal involuntary movements	0.813	0.187
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.813	0.187
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.812	0.188
M54.5 Low back pain	0.810	0.190
Z47 Other orthopaedic follow-up care	0.809	0.191
M25.8 Other specified joint disorders	0.808	0.192
C83 Diffuse non-Hodgkin's lymphoma	0.808	0.192
J43 Emphysema	0.807	0.192
Z02.8 Other examinations for administrative purposes	0.807	0.193
S40-S49 Injuries to the shoulder and upper arm	0.806	0.194
D60-D64 Aplastic and other anaemias	0.804	0.196
S10-S19 Injuries to the neck	0.800	0.200
J09-J18 Influenza and pneumonia	0.797	0.203
J81 Pulmonary oedema	0.793	0.207
S00 Superficial injury of head	0.791	0.209
R30-R39 Symptoms and signs involving the urinary system	0.789	0.211
M24 Other specific joint derangements	0.789	0.211
M05-M14 Inflammatory polyarthropathies	0.787	0.213
T66-T78 Other and unspecified effects of external causes	0.786	0.214
C92 Myeloid leukaemia	0.783	0.217
H60-H62 Diseases of external ear	0.782	0.218
H30-H36 Disorders of choroid and retina	0.781	0.219
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.780	0.220
M47.80 Other spondylosis (Multiple sites in spine)	0.780	0.220
M15-M19 Arthrosis	0.780	0.220
N47 Redundant prepuce, phimosis and paraphimosis	0.779	0.221
S64.4 Injury of digital nerve of other finger	0.778	0.221
T79-T79 Certain early complications of trauma	0.778	0.222
D46.9 Myelodysplastic syndrome, unspecified	0.778	0.222
M54.1 Radiculopathy	0.775	0.225
D45 Polycythaemia vera	0.773	0.227
S72.0 Fracture of neck of femur	0.771	0.229
Z49 Care involving dialysis	0.770	0.230
M53 Other dorsopathies, not elsewhere classified	0.770	0.230
J40 Bronchitis, not specified as acute or chronic	0.768	0.232
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.766	0.234
F20 Schizophrenia	0.766	0.234
D03 Melanoma in situ	0.765	0.235
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.764	0.236
I67 Other cerebrovascular diseases	0.764	0.236
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.763	0.237
Z04 Examination and observation for other reasons	0.762	0.238
J47 Bronchiectasis	0.761	0.239
Chapter I Certain infectious and parasitic diseases	0.761	0.239
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.759	0.241
M91-M94 Chondropathies	0.759	0.241
D63 Anaemia in chronic diseases classified elsewhere	0.758	0.242
C67.9 Bladder, unspecified	0.757	0.243
M23.2 Derangement of meniscus due to old tear or injury	0.757	0.243
N19 Unspecified renal failure	0.756	0.244
S09 Other and unspecified injuries of head	0.755	0.245
C62.9 Testis, unspecified	0.754	0.246
C64 Malignant neoplasm of kidney, except renal pelvis	0.754	0.246
H43.8 Other disorders of vitreous body	0.754	0.246
M54.59 Low back pain (Site unspecified)	0.754	0.246
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.752	0.248
M34 Systemic sclerosis	0.751	0.248
Z41 Procedures for purposes other than remedying health state	0.751	0.249
M80-M85 Disorders of bone density and structure	0.751	0.249
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.751	0.249
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.750	0.250
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.750	0.250
R32 Unspecified urinary incontinence	0.750	0.250
M25.75 Osteophyte (Pelvic region and thigh)	0.750	0.250
M25.3 Other instability of joint	0.749	0.251
N18 Chronic renal failure	0.748	0.252
G35-G37 Demyelinating diseases of the central nervous system	0.748	0.252
Q38-Q45 Other congenital malformations of the digestive system	0.748	0.252
Chapter IV Endocrine, nutritional and metabolic diseases	0.748	0.252
M25.6 Stiffness of joint, not elsewhere classified	0.745	0.255
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.745	0.255
F31 Bipolar affective disorder	0.743	0.257
R31 Unspecified haematuria	0.743	0.257
C67.8 Overlapping lesion of bladder	0.740	0.260
H02 Other disorders of eyelid	0.740	0.260
R25.1 Tremor, unspecified	0.739	0.261
G99 Other disorders of nervous system in diseases classified elsewhere	0.738	0.262
S80 Superficial injury of lower leg	0.737	0.263
F60-F69 Disorders of adult personality and behaviour	0.737	0.263
G93 Other disorders of brain	0.737	0.263
S01.3 Open wound of ear	0.736	0.264
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.736	0.264
Q20-Q28 Congenital malformations of the circulatory system	0.736	0.264
W00-W19 Falls	0.736	0.264
Z50.4 Psychotherapy, not elsewhere classified	0.736	0.264
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.735	0.265
Z45 Adjustment and management of implanted device	0.734	0.266
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.734	0.266
D09 Carcinoma in situ of other and unspecified sites	0.734	0.266
I05-I09 Chronic rheumatic heart diseases	0.733	0.267
N43 Hydrocele and spermatocele	0.733	0.267
Z50.0 Cardiac rehabilitation	0.732	0.268
N00-N08 Glomerular diseases	0.731	0.269
C51-C58 Malignant neoplasms of female genital organs	0.730	0.270
C67.2 Lateral wall of bladder	0.729	0.271
M19 Other arthrosis	0.729	0.271
C83.3 Large cell (diffuse)	0.729	0.271
M00-M03 Infectious arthropathies	0.727	0.273
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.727	0.273
S32 Fracture of lumbar spine and pelvis	0.727	0.273
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.727	0.273
S05 Injury of eye and orbit	0.726	0.274
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.726	0.274
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.726	0.274
H10-H13 Disorders of conjunctiva	0.726	0.274
J44.8 Other specified chronic obstructive pulmonary disease	0.726	0.274
T15-T19 Effects of foreign body entering through natural orifice	0.725	0.274
S61 Open wound of wrist and hand	0.724	0.276
H40.0 Glaucoma suspect	0.722	0.278
M21 Other acquired deformities of limbs	0.721	0.278
Z29 Need for other prophylactic measures	0.721	0.279
S02 Fracture of skull and facial bones	0.721	0.279
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.720	0.280
H61 Other disorders of external ear	0.719	0.281
N48.4 Impotence of organic origin	0.719	0.281
M25.78 Osteophyte (Other)	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
R26.2 Difficulty in walking, not elsewhere classified	0.717	0.283
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284
C63 Malignant neoplasm of other and unspecified male genital organs	0.716	0.284
C60 Malignant neoplasm of penis	0.716	0.284
F00-F09 Organic, including symptomatic, mental disorders	0.716	0.284
H46-H48 Disorders of optic nerve and visual pathways	0.715	0.285
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.715	0.285
N99-N99 Other disorders of the genitourinary system	0.715	0.285
D63.0 Anaemia in neoplastic disease	0.715	0.285
M50.1 Cervical disk disorder with radiculopathy	0.714	0.286
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.714	0.286
S72.00 Fracture of neck of femur (closed)	0.713	0.287
C67.5 Bladder neck	0.712	0.288
J41 Simple and mucopurulent chronic bronchitis	0.711	0.288
S70 Superficial injury of hip and thigh	0.711	0.289
H25-H28 Disorders of lens	0.710	0.290
N10-N16 Renal tubulo-interstitial diseases	0.710	0.290
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.708	0.292
C90 Multiple myeloma and malignant plasma cell neoplasms	0.707	0.293
H55 Nystagmus and other irregular eye movements	0.707	0.293
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.707	0.293
M33 Dermatopolymyositis	0.707	0.293
M32 Systemic lupus erythematosus	0.707	0.293
M30 Polyarteritis nodosa and related conditions	0.707	0.293
Z73 Problems related to life-management difficulty	0.706	0.293
M23.0 Cystic meniscus	0.706	0.294
M20 Acquired deformities of fingers and toes	0.705	0.295
M23.8 Other internal derangements of knee	0.704	0.296
Z54 Convalescence	0.704	0.296
Z52 Donors of organs and tissues	0.704	0.296
Z44 Fitting and adjustment of external prosthetic device	0.704	0.296
N48.0 Leukoplakia of penis	0.703	0.297
Z50.5 Speech therapy	0.702	0.298
M47.82 Other spondylosis (Cervical region)	0.702	0.298
H18.8 Other specified disorders of cornea	0.701	0.299
G20 Parkinson's disease	0.701	0.299
H05 Disorders of orbit	0.700	0.300
Z76 Persons encountering health services in other circumstances	0.699	0.300
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.697	0.303
Z60 Problems related to social environment	0.697	0.303
J60-J70 Lung diseases due to external agents	0.696	0.304
M49 Spondylopathies in diseases classified elsewhere	0.696	0.304
Z40 Prophylactic surgery	0.696	0.304
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.696	0.304
I12 Hypertensive renal disease	0.695	0.305
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.694	0.306
M22 Disorders of patella	0.694	0.306
Z51 Other medical care	0.693	0.307
S42 Fracture of shoulder and upper arm	0.692	0.308
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.692	0.308
J82 Pulmonary eosinophilia, not elsewhere classified	0.692	0.308
V10-V19 Pedal cyclist injured in transport accident	0.691	0.308
G91 Hydrocephalus	0.691	0.309
M46 Other inflammatory spondylopathies	0.689	0.311
H20 Iridocyclitis	0.688	0.312
R26.8 Other and unspecified abnormalities of gait and mobility	0.688	0.312
F17 Mental and behavioural disorders due to use of tobacco	0.687	0.313
Z48 Other surgical follow-up care	0.687	0.313
A30-A49 Other bacterial diseases	0.687	0.313
F23 Acute and transient psychotic disorders	0.686	0.313
Q60-Q64 Congenital malformations of the urinary system	0.686	0.313
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.686	0.314
M25.86 Other specified joint disorders (Lower leg)	0.686	0.314
M47.87 Other spondylosis (Lumbosacral region)	0.686	0.314
F99-F99 Unspecified mental disorder	0.686	0.314
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.686	0.314
F70-F79 Mental retardation	0.686	0.314
M25.9 Joint disorder, unspecified	0.686	0.314
M25.2 Flail joint	0.686	0.314
M25.1 Fistula of joint	0.686	0.314
M25.0 Haemarthrosis	0.686	0.314
F80-F89 Disorders of psychological development	0.685	0.314
H53-H54 Visual disturbances and blindness	0.685	0.315
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.685	0.315
C92.0 Acute myeloid leukaemia	0.685	0.315
M48 Other spondylopathies	0.684	0.316
Z50.6 Orthoptic training	0.683	0.317
Z50.3 Drug rehabilitation	0.683	0.317
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.683	0.317
J42 Unspecified chronic bronchitis	0.683	0.317
M47.1 Other spondylosis with myelopathy	0.683	0.317
M47.0 Anterior spinal and vertebral artery compression syndromes	0.683	0.317
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.682	0.318
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.682	0.318
R93 Abnormal findings on diagnostic imaging of other body structures	0.682	0.318
R91 Abnormal findings on diagnostic imaging of lung	0.681	0.319
I64 Stroke, not specified as haemorrhage or infarction	0.681	0.319
S01.5 Open wound of lip and oral cavity	0.680	0.319
M45 Ankylosing spondylitis	0.680	0.320
S00.0 Superficial injury of scalp	0.680	0.320
R26.3 Immobility	0.679	0.321
Q80-Q89 Other congenital malformations	0.679	0.321
M10 Gout	0.679	0.321
C68 Malignant neoplasm of other and unspecified urinary organs	0.679	0.321
C66 Malignant neoplasm of ureter	0.679	0.321
C65 Malignant neoplasm of renal pelvis	0.679	0.321
I67.8 Other specified cerebrovascular diseases	0.679	0.321
M19.9 Arthrosis, unspecified	0.679	0.321
E20-E35 Disorders of other endocrine glands	0.679	0.321
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.678	0.322
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.678	0.322
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.678	0.322
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.677	0.323
H00 Hordeolum and chalazion	0.677	0.323
D03.3 Melanoma in situ of other and unspecified parts of face	0.677	0.323
F20.0 Paranoid schizophrenia	0.677	0.323
S08 Traumatic amputation of part of head	0.677	0.323
S07 Crushing injury of head	0.677	0.323
S04 Injury of cranial nerves	0.677	0.323
S03 Dislocation, sprain and strain of joints and ligaments of head	0.677	0.323
M23.5 Chronic instability of knee	0.677	0.323
M54.19 Radiculopathy (Site unspecified)	0.677	0.323
S60 Superficial injury of wrist and hand	0.676	0.323
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.676	0.324
H43.3 Other vitreous opacities	0.675	0.325
G00-G09 Inflammatory diseases of the central nervous system	0.675	0.325
M25.74 Osteophyte (Hand)	0.675	0.325
J43.9 Emphysema, unspecified	0.675	0.325
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.675	0.325
H21 Other disorders of iris and ciliary body	0.675	0.325
M47.99 Spondylosis, unspecified (Site unspecified)	0.674	0.326
H04 Disorders of lachrymal system	0.673	0.327
G50-G59 Nerve, nerve root and plexus disorders	0.673	0.327
F33 Recurrent depressive disorder	0.673	0.327
I69 Sequelae of cerebrovascular disease	0.672	0.328
S90-S99 Injuries to the ankle and foot	0.672	0.328
M25.79 Osteophyte (Site unspecified)	0.671	0.328
M25.73 Osteophyte (Forearm)	0.671	0.328
M25.72 Osteophyte (Upper arm)	0.671	0.328
M25.71 Osteophyte (Shoulder region)	0.671	0.328
M25.70 Osteophyte (Multiple sites)	0.671	0.328
I70-I79 Diseases of arteries, arterioles and capillaries	0.671	0.329
Z74 Problems related to care-provider dependency	0.671	0.329
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.670	0.330
S64.2 Injury of radial nerve at wrist and hand level	0.669	0.330
N48.1 Balanoposthitis	0.669	0.331
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.669	0.331
M35 Other systemic involvement of connective tissue	0.669	0.331
J80 Adult respiratory distress syndrome	0.668	0.332
J95-J99 Other diseases of the respiratory system	0.668	0.332
S62 Fracture at wrist and hand level	0.667	0.333
Z04.8 Examination and observation for other specified reasons	0.667	0.333
J84.8 Other specified interstitial pulmonary diseases	0.667	0.333
J84.0 Alveolar and parietoalveolar conditions	0.667	0.333
T98 Sequelae of other and unspecified effects of external causes	0.667	0.333
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.666	0.334
D07 Carcinoma in situ of other and unspecified genital organs	0.665	0.335
I00-I02 Acute rheumatic fever	0.664	0.336
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.663	0.337
R27 Other lack of coordination	0.662	0.337
J15 Bacterial pneumonia, not elsewhere classified	0.662	0.338
N51 Disorders of male genital organs in diseases classified elsewhere	0.661	0.339
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.661	0.339
N46 Male infertility	0.661	0.339
N44 Torsion of testis	0.661	0.339
Chapter XXII Codes for special purposes	0.661	0.339
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.661	0.339
S79 Other and unspecified injuries of hip and thigh	0.661	0.339
S78 Traumatic amputation of hip and thigh	0.661	0.339
S77 Crushing injury of hip and thigh	0.661	0.339
S76 Injury of muscle and tendon at hip and thigh level	0.661	0.339
S75 Injury of blood vessels at hip and thigh level	0.661	0.339
S74 Injury of nerves at hip and thigh level	0.661	0.339
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.661	0.339
S71 Open wound of hip and thigh	0.661	0.339
S50 Superficial injury of forearm	0.660	0.340
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.660	0.340
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.660	0.340
M47.94 Spondylosis, unspecified (Thoracic region)	0.660	0.340
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.660	0.340
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.660	0.340
G95 Other diseases of spinal cord	0.660	0.340
M40-M43 Deforming dorsopathies	0.659	0.340
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.659	0.341
C95 Leukaemia of unspecified cell type	0.659	0.341
C94 Other leukaemias of specified cell type	0.659	0.341
C93 Monocytic leukaemia	0.659	0.341
C88 Malignant immunoproliferative diseases	0.659	0.341
C86 Other specified types of T/NK-cell lymphoma	0.659	0.341
C84 Peripheral and cutaneous T-cell lymphomas	0.659	0.341
C81 Hodgkin's disease	0.659	0.341
D62 Acute posthaemorrhagic anaemia	0.659	0.341
H42 Glaucoma in diseases classified elsewhere	0.659	0.341
I15 Secondary hypertension	0.657	0.342
I13 Hypertensive heart and renal disease	0.657	0.342
I11 Hypertensive heart disease	0.657	0.342
M67 Other disorders of synovium and tendon	0.657	0.343
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.657	0.343
V20-V29 Motorcycle rider injured in transport accident	0.657	0.343
G70-G73 Diseases of myoneural junction and muscle	0.656	0.343
M54.6 Pain in thoracic spine	0.655	0.345
J00-J06 Acute upper respiratory infections	0.655	0.345
Z50.2 Alcohol rehabilitation	0.655	0.345
Z42 Follow-up care involving plastic surgery	0.655	0.345
Z29.2 Other prophylactic chemotherapy	0.654	0.345
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.654	0.346
Q50-Q56 Congenital malformations of genital organs	0.654	0.346
Q35-Q37 Cleft lip and cleft palate	0.654	0.346
Q30-Q34 Congenital malformations of the respiratory system	0.654	0.346
N18.2 Chronic kidney disease, stage 2	0.654	0.346
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.654	0.346
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.654	0.346
S01.7 Multiple open wounds of head	0.653	0.347
S56 Injury of muscle and tendon at forearm level	0.653	0.347
H90-H95 Other disorders of ear	0.652	0.347
Q00-Q07 Congenital malformations of the nervous system	0.652	0.348
H40.5 Glaucoma secondary to other eye disorders	0.651	0.349
N17 Acute renal failure	0.651	0.349
S69 Other and unspecified injuries of wrist and hand	0.650	0.350
S67 Crushing injury of wrist and hand	0.650	0.350
S65 Injury of blood vessels at wrist and hand level	0.650	0.350
F17.1 Harmful use	0.649	0.351
M47.89 Other spondylosis (Site unspecified)	0.649	0.351
H33 Retinal detachments and breaks	0.649	0.351
H16 Keratitis	0.649	0.351
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.648	0.352
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.648	0.352
H17 Corneal scars and opacities	0.648	0.352
H15 Disorders of sclera	0.648	0.352
T94 Sequelae of injuries involving multiple and unspecified body regions	0.648	0.352
M86-M90 Other osteopathies	0.648	0.352
J46 Status asthmaticus	0.648	0.352
S72.3 Fracture of shaft of femur	0.648	0.352
G96 Other disorders of central nervous system	0.647	0.353
Z47.8 Other specified orthopaedic follow-up care	0.647	0.353
H18.4 Corneal degeneration	0.647	0.353
C07 Malignant neoplasm of parotid gland	0.647	0.353
J21 Acute bronchiolitis	0.647	0.353
J20 Acute bronchitis	0.647	0.353
G60 Hereditary and idiopathic neuropathy	0.647	0.353
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.646	0.354
C67.4 Posterior wall of bladder	0.645	0.355
Z85 Personal history of malignant neoplasm	0.645	0.355
M54.50 Low back pain (Multiple sites in spine)	0.645	0.355
Z04.1 Examination and observation following transport accident	0.644	0.356
M51 Other intervertebral disk disorders	0.644	0.356
S72.2 Subtrochanteric fracture	0.644	0.356
S06 Intracranial injury	0.643	0.357
H18.5 Hereditary corneal dystrophies	0.642	0.358
Z85.4 Personal history of malignant neoplasm of genital organs	0.641	0.359
C67.7 Urachus	0.641	0.359
C67.6 Ureteric orifice	0.641	0.359
C67.3 Anterior wall of bladder	0.641	0.359
C67.1 Dome of bladder	0.641	0.359
C67.0 Trigone of bladder	0.641	0.359
W20-W49 Exposure to inanimate mechanical forces	0.640	0.360
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.640	0.360
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.640	0.360
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.640	0.360
N48.2 Other inflammatory disorders of penis	0.640	0.360
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.639	0.360
M70-M79 Other soft tissue disorders	0.639	0.361
M23.4 Loose body in knee	0.639	0.361
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.638	0.362
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.637	0.363
D09.0 Bladder	0.636	0.364
R95-R99 Ill-defined and unknown causes of mortality	0.636	0.364
M65 Synovitis and tenosynovitis	0.636	0.364
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.635	0.365
S80.9 Superficial injury of lower leg, unspecified	0.635	0.365
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.635	0.365
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.635	0.365
H03 Disorders of eyelid in diseases classified elsewhere	0.635	0.365
S72.1 Pertrochanteric fracture	0.635	0.365
H61.0 Perichondritis of external ear	0.635	0.365
G25 Other extrapyramidal and movement disorders	0.635	0.365
R30 Pain associated with micturition	0.635	0.365
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.634	0.366
I68 Cerebrovascular disorders in diseases classified elsewhere	0.634	0.366
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.634	0.366
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.634	0.366
R25.3 Fasciculation	0.633	0.367
I60 Subarachnoid haemorrhage	0.633	0.367
T78 Adverse effects, not elsewhere classified	0.633	0.367
R26.0 Ataxic gait	0.632	0.367
G94 Other disorders of brain in diseases classified elsewhere	0.632	0.368
G90 Disorders of autonomic nervous system	0.632	0.368
G98 Other disorders of nervous system, not elsewhere classified	0.632	0.368
G92 Toxic encephalopathy	0.632	0.368
M54.8 Other dorsalgia	0.632	0.368
M54.0 Panniculitis affecting regions of neck and back	0.632	0.368
M31 Other necrotising vasculopathies	0.631	0.368

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations