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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78262206
log Bayes Factor = 37.9756
Chromosome 1   position 31,792,220  (GRCh37) Explore rs78262206 on Ensembl!
Variant rs78262206 is part of Cluster X0037

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
K55-K64 Other diseases of intestines
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z87 Personal history of other diseases and conditions
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
K70-K77 Diseases of liver
0.999 0.001 0.000
K76 Other diseases of liver
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.996 0.004 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.995 0.005 0.000
R05 Cough
0.995 0.005 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.994 0.006 0.000
K63 Other diseases of intestine
0.993 0.007 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.993 0.007 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.990 0.010 0.000
Z87.1 Personal history of diseases of the digestive system
0.990 0.010 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.990 0.010 0.000
E70-E90 Metabolic disorders
0.989 0.011 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.989 0.011 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.988 0.012 0.000
Chapter XIV Diseases of the genitourinary system
0.987 0.013 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.987 0.013 0.000
R07 Pain in throat and chest
0.987 0.013 0.000
R50-R69 General symptoms and signs
0.986 0.014 0.000
C15-C26 Malignant neoplasms of digestive organs
0.984 0.016 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.983 0.017 0.000
Z93 Artificial opening status
0.981 0.019 0.000
F10.2 Dependence syndrome
0.979 0.021 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.978 0.022 0.000
K57 Diverticular disease of intestine
0.974 0.026 0.000
Z72 Problems related to lifestyle
0.973 0.027 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.973 0.027 0.000
K63.5 Polyp of colon
0.972 0.028 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.971 0.029 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.971 0.029 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.969 0.031 0.000
N17-N19 Renal failure
0.969 0.031 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.967 0.033 0.000
R26 Abnormalities of gait and mobility
0.959 0.041 0.000
R30-R39 Symptoms and signs involving the urinary system
0.959 0.041 0.000
Chapter VIII Diseases of the ear and mastoid process
0.957 0.043 0.000
E10-E14 Diabetes mellitus
0.956 0.044 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.955 0.045 0.000
H02 Other disorders of eyelid
0.953 0.047 0.000
R53 Malaise and fatigue
0.953 0.047 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.952 0.048 0.000
K22 Other diseases of oesophagus
0.951 0.049 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.949 0.051 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.949 0.051 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.945 0.055 0.000
F10.1 Harmful use
0.945 0.055 0.000
Z98 Other postsurgical states
0.945 0.055 0.000
K76.8 Other specified diseases of liver
0.942 0.058 0.000
C20 Malignant neoplasm of rectum
0.942 0.058 0.000
R04 Haemorrhage from respiratory passages
0.939 0.061 0.000
D10-D36 Benign neoplasms
0.936 0.064 0.000
O60-O75 Complications of labour and delivery
0.936 0.064 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.934 0.066 0.000
Z04 Examination and observation for other reasons
0.934 0.066 0.000
N17 Acute renal failure
0.932 0.068 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.929 0.071 0.000
Z72.0 Tobacco use
0.928 0.072 0.000
F10.0 Acute intoxication
0.926 0.074 0.000
K56.6 Other and unspecified intestinal obstruction
0.924 0.076 0.000
K56.2 Volvulus
0.924 0.076 0.000
R07.4 Chest pain, unspecified
0.923 0.077 0.000
C34 Malignant neoplasm of bronchus and lung
0.923 0.077 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.922 0.078 0.000
N18 Chronic renal failure
0.920 0.080 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.920 0.080 0.000
R13 Dysphagia
0.919 0.081 0.000
O00-O08 Pregnancy with abortive outcome
0.917 0.083 0.000
Z98.0 Intestinal bypass and anastomosis status
0.914 0.086 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.913 0.087 0.000
N17.9 Acute renal failure, unspecified
0.905 0.095 0.000
R04.2 Haemoptysis
0.902 0.098 0.000
K59 Other functional intestinal disorders
0.900 0.100 0.000
H04 Disorders of lachrymal system
0.899 0.101 0.000
S20-S29 Injuries to the thorax
0.897 0.103 0.000
D23 Other benign neoplasms of skin
0.894 0.106 0.000
N10-N16 Renal tubulo-interstitial diseases
0.892 0.108 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.891 0.109 0.000
K25 Gastric ulcer
0.891 0.109 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.888 0.112 0.000
Z93.3 Colostomy status
0.887 0.113 0.000
Chapter XX External causes of morbidity and mortality
0.885 0.115 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.884 0.116 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.884 0.116 0.000
R60 Oedema, not elsewhere classified
0.884 0.116 0.000
L60-L75 Disorders of skin appendages
0.883 0.117 0.000
Z04.9 Examination and observation for unspecified reason
0.883 0.117 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.881 0.119 0.000
R79 Other abnormal findings of blood chemistry
0.880 0.120 0.000
Chapter X Diseases of the respiratory system
0.878 0.122 0.000
C34.1 Upper lobe, bronchus or lung
0.878 0.122 0.000
R07.2 Precordial pain
0.873 0.127 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.872 0.128 0.000
Z93.2 Ileostomy status
0.868 0.132 0.000
Z87.8 Personal history of other specified conditions
0.867 0.133 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.867 0.133 0.000
E14 Unspecified diabetes mellitus
0.866 0.134 0.000
Z72.1 Alcohol use
0.865 0.135 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.865 0.135 0.000
K22.8 Other specified diseases of oesophagus
0.864 0.136 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.864 0.136 0.000
H53-H54 Visual disturbances and blindness
0.863 0.137 0.000
Chapter IX Diseases of the circulatory system
0.863 0.137 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.863 0.137 0.000
R55 Syncope and collapse
0.862 0.138 0.000
J40-J47 Chronic lower respiratory diseases
0.862 0.138 0.000
S00-S09 Injuries to the head
0.862 0.138 0.000
R39 Other symptoms and signs involving the urinary system
0.861 0.139 0.000
R07.3 Other chest pain
0.860 0.140 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.859 0.141 0.000
E86 Volume depletion
0.858 0.142 0.000
R17 Unspecified jaundice
0.857 0.143 0.000
D23.5 Skin of trunk
0.856 0.144 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.854 0.146 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.853 0.146 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.853 0.146 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.852 0.148 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.851 0.149 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.849 0.151 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.848 0.152 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.844 0.156 0.000
K63.1 Perforation of intestine (nontraumatic)
0.843 0.157 0.000
K20 Oesophagitis
0.842 0.158 0.000
H30-H36 Disorders of choroid and retina
0.842 0.158 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.841 0.159 0.000
S80-S89 Injuries to the knee and lower leg
0.840 0.160 0.000
C18 Malignant neoplasm of colon
0.838 0.162 0.000
Chapter VI Diseases of the nervous system
0.838 0.162 0.000
H90-H95 Other disorders of ear
0.837 0.163 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.836 0.164 0.000
H02.5 Other disorders affecting eyelid function
0.835 0.165 0.000
K76.9 Liver disease, unspecified
0.834 0.166 0.000
H65-H75 Diseases of middle ear and mastoid
0.834 0.166 0.000
K90-K93 Other diseases of the digestive system
0.832 0.168 0.000
T66-T78 Other and unspecified effects of external causes
0.831 0.169 0.000
H02.9 Disorder of eyelid, unspecified
0.829 0.171 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.827 0.173 0.000
Z04.8 Examination and observation for other specified reasons
0.827 0.173 0.000
K29 Gastritis and duodenitis
0.825 0.175 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.825 0.175 0.000
R35 Polyuria
0.824 0.176 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.824 0.176 0.000
Z93.1 Gastrostomy status
0.824 0.176 0.000
N18.9 Chronic renal failure, unspecified
0.823 0.177 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.821 0.179 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.821 0.179 0.000
E87.2 Acidosis
0.821 0.179 0.000
C34.9 Bronchus or lung, unspecified
0.815 0.185 0.000
R01 Cardiac murmurs and other cardiac sounds
0.815 0.185 0.000
E14.9 Without complications
0.814 0.186 0.000
R18 Ascites
0.813 0.187 0.000
C15 Malignant neoplasm of oesophagus
0.812 0.187 0.000
K65-K67 Diseases of peritoneum
0.812 0.188 0.000
I95 Hypotension
0.811 0.189 0.000
R63 Symptoms and signs concerning food and fluid intake
0.809 0.191 0.000
J44 Other chronic obstructive pulmonary disease
0.808 0.192 0.000
K31 Other diseases of stomach and duodenum
0.807 0.193 0.000
Z89 Acquired absence of limb
0.806 0.194 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.806 0.194 0.000
R73 Elevated blood glucose level
0.806 0.194 0.000
O03 Spontaneous abortion
0.802 0.198 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.802 0.198 0.000
R02 Gangrene, not elsewhere classified
0.801 0.199 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.801 0.199 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.800 0.200 0.000
E10 Insulin-dependent diabetes mellitus
0.800 0.200 0.000
Z73 Problems related to life-management difficulty
0.800 0.200 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.800 0.200 0.000
D17 Benign lipomatous neoplasm
0.800 0.200 0.000
K56.0 Paralytic ileus
0.798 0.202 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.798 0.202 0.000
H43-H45 Disorders of vitreous body and globe
0.797 0.203 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.796 0.204 0.000
D00-D09 In situ neoplasms
0.795 0.205 0.000
R30 Pain associated with micturition
0.795 0.205 0.000
R33 Retention of urine
0.795 0.205 0.000
S90-S99 Injuries to the ankle and foot
0.795 0.205 0.000
H02.4 Ptosis of eyelid
0.794 0.206 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.794 0.206 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.793 0.207 0.000
H04.1 Other disorders of lachrymal gland
0.792 0.208 0.000
S40-S49 Injuries to the shoulder and upper arm
0.792 0.208 0.000
N18.3 Chronic kidney disease, stage 3
0.791 0.209 0.000
H60-H62 Diseases of external ear
0.791 0.209 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.791 0.209 0.000
K63.2 Fistula of intestine
0.790 0.210 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.790 0.210 0.000
Z72.2 Drug use
0.789 0.211 0.000
K61 Abscess of anal and rectal regions
0.789 0.211 0.000
N89 Other noninflammatory disorders of vagina
0.788 0.212 0.000
O63 Long labour
0.788 0.212 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.788 0.212 0.000
R94 Abnormal results of function studies
0.787 0.213 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.787 0.213 0.000
N84 Polyp of female genital tract
0.787 0.213 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.786 0.214 0.000
E65-E68 Obesity and other hyperalimentation
0.786 0.214 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.786 0.214 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.786 0.214 0.000
N00-N08 Glomerular diseases
0.786 0.214 0.000
R57 Shock, not elsewhere classified
0.785 0.215 0.000
F99-F99 Unspecified mental disorder
0.785 0.215 0.000
K74 Fibrosis and cirrhosis of liver
0.785 0.215 0.000
L20-L30 Dermatitis and eczema
0.785 0.215 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.785 0.215 0.000
E11 Non-insulin-dependent diabetes mellitus
0.783 0.217 0.000
R27 Other lack of coordination
0.783 0.217 0.000
H10-H13 Disorders of conjunctiva
0.783 0.217 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.782 0.218 0.000
Chapter I Certain infectious and parasitic diseases
0.782 0.218 0.000
K22.2 Oesophageal obstruction
0.781 0.219 0.000
K22.7 Barrett's oesophagus
0.781 0.219 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.781 0.219 0.000
J43 Emphysema
0.780 0.220 0.000
K59.0 Constipation
0.778 0.222 0.000
T85.2 Mechanical complication of intraocular lens
0.776 0.224 0.000
R68 Other general symptoms and signs
0.776 0.224 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.774 0.226 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.773 0.227 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.773 0.227 0.000
K29.8 Duodenitis
0.772 0.228 0.000
K22.1 Ulcer of oesophagus
0.770 0.230 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.770 0.230 0.000
J00-J06 Acute upper respiratory infections
0.770 0.230 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.769 0.231 0.000
R25 Abnormal involuntary movements
0.768 0.232 0.000
K63.3 Ulcer of intestine
0.768 0.232 0.000
I95.9 Hypotension, unspecified
0.767 0.233 0.000
K63.8 Other specified diseases of intestine
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.766 0.234 0.000
N13 Obstructive and reflux uropathy
0.766 0.234 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.765 0.235 0.000
R07.0 Pain in throat
0.765 0.235 0.000
D23.1 Skin of eyelid, including canthus
0.763 0.237 0.000
Z93.0 Tracheostomy status
0.763 0.237 0.000
R39.1 Other difficulties with micturition
0.762 0.238 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.762 0.238 0.000
D26 Other benign neoplasms of uterus
0.761 0.239 0.000
H55-H59 Other disorders of eye and adnexa
0.761 0.239 0.000
K56.7 Ileus, unspecified
0.760 0.239 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.759 0.241 0.000
L82 Seborrhoeic keratosis
0.759 0.241 0.000
Chapter XXII Codes for special purposes
0.758 0.241 0.000
R54 Senility
0.758 0.242 0.000
K85 Acute pancreatitis
0.758 0.242 0.000
R60.0 Localised oedema
0.758 0.242 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.757 0.243 0.000
E50-E64 Other nutritional deficiencies
0.756 0.244 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.754 0.246 0.000
O62 Abnormalities of forces of labour
0.753 0.247 0.000
H33 Retinal detachments and breaks
0.753 0.247 0.000
E80.4 Gilbert's syndrome
0.753 0.247 0.000
D10 Benign neoplasm of mouth and pharynx
0.751 0.249 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.751 0.249 0.000
Z74 Problems related to care-provider dependency
0.751 0.249 0.000
N20-N23 Urolithiasis
0.751 0.249 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.750 0.250 0.000
O02 Other abnormal products of conception
0.750 0.250 0.000
D48.7 Other specified sites
0.750 0.250 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.749 0.251 0.000
L50-L54 Urticaria and erythema
0.749 0.251 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.747 0.253 0.000
R61 Hyperhidrosis
0.747 0.253 0.000
E87.5 Hyperkalaemia
0.747 0.253 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.746 0.254 0.000
R74 Abnormal serum enzyme levels
0.746 0.254 0.000
H02.3 Blepharochalasis
0.743 0.257 0.000
L89 Decubitus ulcer
0.743 0.257 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.743 0.257 0.000
C51-C58 Malignant neoplasms of female genital organs
0.742 0.258 0.000
S01 Open wound of head
0.742 0.258 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.741 0.258 0.000
L90 Atrophic disorders of skin
0.740 0.260 0.000
Z94 Transplanted organ and tissue status
0.740 0.260 0.000
Z82.3 Family history of stroke
0.739 0.261 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.739 0.261 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.738 0.261 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.738 0.262 0.000
D22 Melanocytic naevi
0.738 0.262 0.000
R60.9 Oedema, unspecified
0.737 0.263 0.000
K22.0 Achalasia of cardia
0.737 0.263 0.000
K63.9 Disease of intestine, unspecified
0.736 0.264 0.000
T86 Failure and rejection of transplanted organs and tissues
0.736 0.264 0.000
R10 Abdominal and pelvic pain
0.733 0.267 0.000
K75 Other inflammatory liver diseases
0.733 0.267 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.732 0.268 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.732 0.268 0.000
H54 Blindness and low vision
0.732 0.268 0.000
E87.0 Hyperosmolality and hypernatraemia
0.732 0.268 0.000
I60-I69 Cerebrovascular diseases
0.732 0.268 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.732 0.268 0.000
F10.3 Withdrawal state
0.729 0.271 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.729 0.271 0.000
N86 Erosion and ectropion of cervix uteri
0.728 0.272 0.000
D34 Benign neoplasm of thyroid gland
0.728 0.272 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.727 0.273 0.000
T79-T79 Certain early complications of trauma
0.727 0.273 0.000
N18.5 Chronic kidney disease, stage 5
0.727 0.273 0.000
K56.4 Other impaction of intestine
0.725 0.275 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.725 0.275 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.725 0.275 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.724 0.276 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.724 0.276 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.723 0.276 0.000
H02.1 Ectropion of eyelid
0.723 0.277 0.000
K27 Peptic ulcer, site unspecified
0.722 0.278 0.000
N18.0 End-stage renal disease
0.721 0.279 0.000
L73 Other follicular disorders
0.721 0.279 0.000
J43.9 Emphysema, unspecified
0.721 0.279 0.000
S02 Fracture of skull and facial bones
0.720 0.280 0.000
K83 Other diseases of biliary tract
0.720 0.280 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.720 0.280 0.000
K55 Vascular disorders of intestine
0.719 0.281 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.719 0.281 0.000
K59.1 Functional diarrhoea
0.718 0.282 0.000
K35-K38 Diseases of appendix
0.718 0.282 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
H02.0 Entropion and trichiasis of eyelid
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
D46 Myelodysplastic syndromes
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.717 0.283 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.717 0.283 0.000
R21 Rash and other nonspecific skin eruption
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.716 0.284 0.000
K73 Chronic hepatitis, not elsewhere classified
0.716 0.284 0.000
K72 Hepatic failure, not elsewhere classified
0.716 0.284 0.000
K71 Toxic liver disease
0.716 0.284 0.000
C25 Malignant neoplasm of pancreas
0.716 0.284 0.000
K76.7 Hepatorenal syndrome
0.716 0.284 0.000
K76.5 Hepatic veno-occlusive disease
0.716 0.284 0.000
K76.4 Peliosis hepatis
0.716 0.284 0.000
K76.3 Infarction of liver
0.716 0.284 0.000
K76.2 Central haemorrhagic necrosis of liver
0.716 0.284 0.000
K76.1 Chronic passive congestion of liver
0.716 0.284 0.000
N84.0 Polyp of corpus uteri
0.716 0.284 0.000
O00 Ectopic pregnancy
0.716 0.284 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F60-F69 Disorders of adult personality and behaviour
0.715 0.285 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.715 0.285 0.000
K56.3 Gallstone ileus
0.714 0.286 0.000
K56.1 Intussusception
0.714 0.286 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.714 0.286 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.714 0.286 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.714 0.286 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.714 0.286 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.714 0.286 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.714 0.286 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.714 0.286 0.000
F11 Mental and behavioural disorders due to use of opioids
0.714 0.286 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.713 0.286 0.000
F10.9 Unspecified mental and behavioural disorder
0.713 0.287 0.000
F10.8 Other mental and behavioural disorders
0.713 0.287 0.000
F10.7 Residual and late-onset psychotic disorder
0.713 0.287 0.000
F10.6 Amnesic syndrome
0.713 0.287 0.000
F10.5 Psychotic disorder
0.713 0.287 0.000
F10.4 Withdrawal state with delirium
0.713 0.287 0.000
N11 Chronic tubulo-interstitial nephritis
0.713 0.287 0.000
C64-C68 Malignant neoplasms of urinary tract
0.713 0.287 0.000
Z85 Personal history of malignant neoplasm
0.712 0.288 0.000
N85.0 Endometrial glandular hyperplasia
0.712 0.288 0.000
K63.4 Enteroptosis
0.712 0.288 0.000
K63.0 Abscess of intestine
0.712 0.288 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.712 0.288 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.712 0.288 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.712 0.288 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.712 0.288 0.000
Z82.2 Family history of deafness and hearing loss
0.712 0.288 0.000
Z82.1 Family history of blindness and visual loss
0.712 0.288 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.712 0.288 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.288 0.000
N60-N64 Disorders of breast
0.711 0.289 0.000
O85-O92 Complications predominantly related to the puerperium
0.710 0.290 0.000
Z76 Persons encountering health services in other circumstances
0.710 0.290 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.710 0.290 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.709 0.291 0.000
E88 Other metabolic disorders
0.709 0.291 0.000
E85 Amyloidosis
0.709 0.291 0.000
E84 Cystic fibrosis
0.709 0.291 0.000
E79 Disorders of purine and pyrimidine metabolism
0.709 0.291 0.000
E77 Disorders of glycoprotein metabolism
0.709 0.291 0.000
E76 Disorders of glycosaminoglycan metabolism
0.709 0.291 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.709 0.291 0.000
E74 Other disorders of carbohydrate metabolism
0.709 0.291 0.000
E73 Lactose intolerance
0.709 0.291 0.000
E72 Other disorders of amino-acid metabolism
0.709 0.291 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.709 0.291 0.000
E70 Disorders of aromatic amino-acid metabolism
0.709 0.291 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.709 0.291 0.000
K28 Gastrojejunal ulcer
0.709 0.291 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.709 0.291 0.000
S27 Injury of other and unspecified intrathoracic organs
0.709 0.291 0.000
R07.1 Chest pain on breathing
0.707 0.292 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.707 0.293 0.000
R62 Lack of expected normal physiological development
0.707 0.293 0.000
R64 Cachexia
0.707 0.293 0.000
R58 Haemorrhage, not elsewhere classified
0.707 0.293 0.000
W00-W19 Falls
0.707 0.293 0.000
O03.4 Incomplete, without complication
0.707 0.293 0.000
J02 Acute pharyngitis
0.706 0.294 0.000
H65 Nonsuppurative otitis media
0.706 0.294 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.706 0.294 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.705 0.294 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.705 0.295 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.705 0.295 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.705 0.295 0.000
C21 Malignant neoplasm of anus and anal canal
0.705 0.295 0.000
C17 Malignant neoplasm of small intestine
0.705 0.295 0.000
C23 Malignant neoplasm of gallbladder
0.705 0.295 0.000
T87 Complications peculiar to reattachment and amputation
0.705 0.295 0.000
Z93.9 Artificial opening status, unspecified
0.703 0.297 0.000
Z93.8 Other artificial opening status
0.703 0.297 0.000
Z93.5 Cystostomy status
0.703 0.297 0.000
H80-H83 Diseases of inner ear
0.703 0.297 0.000
H18 Other disorders of cornea
0.703 0.297 0.000
N85.4 Malposition of uterus
0.702 0.298 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.702 0.298 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.701 0.299 0.000
H05 Disorders of orbit
0.701 0.299 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.701 0.299 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.701 0.299 0.000
H93 Other disorders of ear, not elsewhere classified
0.700 0.300 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.700 0.300 0.000
O66 Other obstructed labour
0.699 0.301 0.000
R15 Faecal incontinence
0.699 0.301 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.698 0.301 0.000
K76.6 Portal hypertension
0.698 0.302 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.698 0.302 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.698 0.302 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.698 0.302 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.698 0.302 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.698 0.302 0.000
K25.7 Chronic without haemorrhage or perforation
0.698 0.302 0.000
Z72.9 Problem related to lifestyle, unspecified
0.698 0.302 0.000
Z72.8 Other problems related to lifestyle
0.698 0.302 0.000
Z72.6 Gambling and betting
0.698 0.302 0.000
Z72.5 High-risk sexual behaviour
0.698 0.302 0.000
Z72.4 Inappropriate diet and eating habits
0.698 0.302 0.000
Z72.3 Lack of physical exercise
0.698 0.302 0.000
L10-L14 Bullous disorders
0.698 0.302 0.000
S70-S79 Injuries to the hip and thigh
0.697 0.303 0.000
K70 Alcoholic liver disease
0.697 0.303 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.696 0.304 0.000
R77 Other abnormalities of plasma proteins
0.696 0.304 0.000
R76 Other abnormal immunological findings in serum
0.696 0.304 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.696 0.304 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.696 0.304 0.000
R71 Abnormality of red blood cells
0.696 0.304 0.000
C16 Malignant neoplasm of stomach
0.696 0.304 0.000
D48.6 Breast
0.695 0.305 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.695 0.305 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.694 0.306 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.694 0.306 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.694 0.306 0.000
Z10 Routine general health check-up of defined subpopulation
0.693 0.307 0.000
H02.8 Other specified disorders of eyelid
0.693 0.307 0.000
S20 Superficial injury of thorax
0.693 0.307 0.000
K86 Other diseases of pancreas
0.692 0.308 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.692 0.308 0.000
R10.4 Other and unspecified abdominal pain
0.692 0.308 0.000
G90-G99 Other disorders of the nervous system
0.692 0.308 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.692 0.308 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.692 0.308 0.000
J47 Bronchiectasis
0.691 0.309 0.000
K85.9 Acute pancreatitis, unspecified
0.691 0.309 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.691 0.309 0.000
R12 Heartburn
0.691 0.309 0.000
H21 Other disorders of iris and ciliary body
0.690 0.309 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.690 0.310 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.690 0.310 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.690 0.310 0.000
R59 Enlarged lymph nodes
0.689 0.310 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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