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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78275630
log Bayes Factor = 11.943
Chromosome 15   position 58,202,985  (GRCh37) Explore rs78275630 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
A30-A49 Other bacterial diseases
0.993 0.007 0.000
M20 Acquired deformities of fingers and toes
0.991 0.009 0.000
A41 Other septicaemia
0.990 0.010 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.985 0.015 0.000
A41.9 Septicaemia, unspecified
0.976 0.024 0.000
H02 Other disorders of eyelid
0.975 0.025 0.000
D10-D36 Benign neoplasms
0.973 0.027 0.000
H53-H54 Visual disturbances and blindness
0.973 0.027 0.000
M80-M85 Disorders of bone density and structure
0.971 0.029 0.000
Chapter XXI Factors influencing health status and contact with health services
0.967 0.033 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.964 0.036 0.000
S00-S09 Injuries to the head
0.964 0.036 0.000
S40-S49 Injuries to the shoulder and upper arm
0.960 0.040 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.960 0.040 0.000
H02.0 Entropion and trichiasis of eyelid
0.957 0.043 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.950 0.050 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.948 0.052 0.000
Z93 Artificial opening status
0.943 0.057 0.000
S01 Open wound of head
0.939 0.061 0.000
Chapter XX External causes of morbidity and mortality
0.938 0.062 0.000
D24 Benign neoplasm of breast
0.937 0.063 0.000
M23 Internal derangement of knee
0.935 0.065 0.000
Z80 Family history of malignant neoplasm
0.935 0.065 0.000
D70 Agranulocytosis
0.933 0.067 0.000
D00-D09 In situ neoplasms
0.932 0.068 0.000
M20.1 Hallux valgus (acquired)
0.927 0.073 0.000
Z98 Other postsurgical states
0.924 0.076 0.000
L20-L30 Dermatitis and eczema
0.922 0.078 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.920 0.080 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.918 0.082 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.918 0.082 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.913 0.087 0.000
H53 Visual disturbances
0.912 0.088 0.000
Chapter V Mental and behavioural disorders
0.905 0.095 0.000
Z85 Personal history of malignant neoplasm
0.903 0.097 0.000
D17 Benign lipomatous neoplasm
0.902 0.098 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.900 0.100 0.000
H02.1 Ectropion of eyelid
0.899 0.101 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.897 0.103 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.897 0.103 0.000
L30 Other dermatitis
0.896 0.104 0.000
M84 Disorders of continuity of bone
0.890 0.110 0.000
H54 Blindness and low vision
0.887 0.113 0.000
S01.8 Open wound of other parts of head
0.883 0.117 0.000
D12.8 Rectum
0.882 0.118 0.000
Chapter VI Diseases of the nervous system
0.878 0.122 0.000
L30.9 Dermatitis, unspecified
0.877 0.123 0.000
S42 Fracture of shoulder and upper arm
0.877 0.123 0.000
M20.4 Other hammer toe(s) (acquired)
0.875 0.125 0.000
M24 Other specific joint derangements
0.874 0.126 0.000
S50-S59 Injuries to the elbow and forearm
0.870 0.130 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.868 0.132 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.866 0.134 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.859 0.141 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.859 0.141 0.000
M70-M79 Other soft tissue disorders
0.857 0.143 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.855 0.145 0.000
H43-H45 Disorders of vitreous body and globe
0.853 0.147 0.000
H53.1 Subjective visual disturbances
0.851 0.149 0.000
D23 Other benign neoplasms of skin
0.848 0.152 0.000
Z98.8 Other specified postsurgical states
0.846 0.154 0.000
M23.3 Other meniscus derangements
0.843 0.157 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.842 0.158 0.000
S40 Superficial injury of shoulder and upper arm
0.838 0.162 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.837 0.163 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.835 0.165 0.000
M80 Osteoporosis with pathological fracture
0.833 0.167 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.833 0.167 0.000
A46 Erysipelas
0.831 0.169 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.830 0.170 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.830 0.170 0.000
A40 Streptococcal septicaemia
0.828 0.172 0.000
D05 Carcinoma in situ of breast
0.827 0.173 0.000
S20-S29 Injuries to the thorax
0.826 0.174 0.000
Z98.0 Intestinal bypass and anastomosis status
0.824 0.176 0.000
C15-C26 Malignant neoplasms of digestive organs
0.821 0.179 0.000
Z93.1 Gastrostomy status
0.819 0.181 0.000
H05 Disorders of orbit
0.816 0.184 0.000
Z94 Transplanted organ and tissue status
0.816 0.184 0.000
M21 Other acquired deformities of limbs
0.815 0.185 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.815 0.185 0.000
M05-M14 Inflammatory polyarthropathies
0.814 0.186 0.000
Z99.8 Dependence on other enabling machines and devices
0.813 0.187 0.000
M20.2 Hallux rigidus
0.813 0.187 0.000
M23.8 Other internal derangements of knee
0.809 0.191 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.808 0.192 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.807 0.193 0.000
T79-T79 Certain early complications of trauma
0.806 0.193 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.806 0.194 0.000
M22 Disorders of patella
0.806 0.194 0.000
M81 Osteoporosis without pathological fracture
0.803 0.197 0.000
D13.1 Stomach
0.802 0.198 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.801 0.199 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.800 0.200 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.798 0.202 0.000
Z83 Family history of other specific disorders
0.798 0.202 0.000
F80-F89 Disorders of psychological development
0.796 0.204 0.000
H52 Disorders of refraction and accommodation
0.796 0.204 0.000
D04 Carcinoma in situ of skin
0.795 0.205 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.793 0.207 0.000
A41.8 Other specified septicaemia
0.791 0.209 0.000
Z93.2 Ileostomy status
0.791 0.209 0.000
H02.3 Blepharochalasis
0.791 0.209 0.000
M40-M43 Deforming dorsopathies
0.789 0.211 0.000
S10-S19 Injuries to the neck
0.789 0.211 0.000
M65-M68 Disorders of synovium and tendon
0.787 0.213 0.000
M34 Systemic sclerosis
0.783 0.217 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.783 0.217 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.781 0.219 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.780 0.220 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.779 0.221 0.000
S42.0 Fracture of clavicle
0.779 0.221 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.777 0.223 0.000
M20.0 Deformity of finger(s)
0.775 0.225 0.000
H55-H59 Other disorders of eye and adnexa
0.774 0.226 0.000
L60-L75 Disorders of skin appendages
0.774 0.226 0.000
H02.9 Disorder of eyelid, unspecified
0.773 0.226 0.000
D75 Other diseases of blood and blood-forming organs
0.773 0.227 0.000
A49 Bacterial infection of unspecified site
0.772 0.228 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.771 0.229 0.000
Y40 Systemic antibiotics
0.771 0.229 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.770 0.230 0.000
M35 Other systemic involvement of connective tissue
0.769 0.231 0.000
C34 Malignant neoplasm of bronchus and lung
0.769 0.231 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.767 0.233 0.000
H43 Disorders of vitreous body
0.767 0.233 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.765 0.235 0.000
L50-L54 Urticaria and erythema
0.765 0.235 0.000
Z93.6 Other artificial openings of urinary tract status
0.763 0.237 0.000
Z93.3 Colostomy status
0.763 0.237 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.763 0.237 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.762 0.238 0.000
B99-B99 Other infectious diseases
0.761 0.239 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.760 0.240 0.000
H53.8 Other visual disturbances
0.759 0.241 0.000
W20-W49 Exposure to inanimate mechanical forces
0.758 0.242 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.758 0.242 0.000
H49 Paralytic strabismus
0.757 0.242 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.757 0.243 0.000
H54.0 Blindness, both eyes
0.757 0.243 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.756 0.244 0.000
L40-L45 Papulosquamous disorders
0.755 0.245 0.000
D68 Other coagulation defects
0.755 0.245 0.000
G90-G99 Other disorders of the nervous system
0.755 0.245 0.000
S01.4 Open wound of cheek and temporomandibular area
0.754 0.246 0.000
H04 Disorders of lachrymal system
0.753 0.247 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.752 0.248 0.000
Chapter X Diseases of the respiratory system
0.751 0.249 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.750 0.249 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.750 0.250 0.000
S90-S99 Injuries to the ankle and foot
0.748 0.252 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.748 0.252 0.000
M86-M90 Other osteopathies
0.747 0.253 0.000
S00 Superficial injury of head
0.747 0.253 0.000
H30-H36 Disorders of choroid and retina
0.746 0.254 0.000
S01.1 Open wound of eyelid and periocular area
0.746 0.254 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.745 0.255 0.000
C51-C58 Malignant neoplasms of female genital organs
0.745 0.255 0.000
T66-T78 Other and unspecified effects of external causes
0.744 0.256 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.742 0.258 0.000
Z91.6 Personal history of other physical trauma
0.742 0.258 0.000
Z93.5 Cystostomy status
0.742 0.258 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.741 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.741 0.259 0.000
S05 Injury of eye and orbit
0.741 0.259 0.000
M85 Other disorders of bone density and structure
0.739 0.261 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.738 0.262 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.738 0.262 0.000
H10-H13 Disorders of conjunctiva
0.738 0.262 0.000
Z99.1 Dependence on respirator
0.738 0.262 0.000
A80-A89 Viral infections of the central nervous system
0.735 0.265 0.000
S01.2 Open wound of nose
0.735 0.265 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.735 0.265 0.000
S02 Fracture of skull and facial bones
0.734 0.266 0.000
L29 Pruritus
0.733 0.267 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.732 0.268 0.000
H50 Other strabismus
0.731 0.269 0.000
J09-J18 Influenza and pneumonia
0.731 0.269 0.000
Z85.6 Personal history of leukaemia
0.731 0.269 0.000
D05.1 Intraductal carcinoma in situ
0.731 0.269 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.730 0.270 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.728 0.272 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.727 0.273 0.000
H54.4 Blindness, one eye
0.726 0.274 0.000
C15 Malignant neoplasm of oesophagus
0.725 0.275 0.000
C91 Lymphoid leukaemia
0.725 0.275 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.723 0.276 0.000
H54.9 Unspecified visual impairment (binocular)
0.721 0.279 0.000
V10-V19 Pedal cyclist injured in transport accident
0.720 0.280 0.000
M23.5 Chronic instability of knee
0.720 0.280 0.000
Z99.2 Dependence on renal dialysis
0.720 0.280 0.000
S51 Open wound of forearm
0.719 0.281 0.000
G57 Mononeuropathies of lower limb
0.719 0.281 0.000
V40-V49 Car occupant injured in transport accident
0.719 0.281 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.718 0.281 0.000
M20.3 Other deformity of hallux (acquired)
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.718 0.282 0.000
X20-X29 Contact with venomous animals and plants
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
Z94.2 Lung transplant status
0.715 0.285 0.000
D55-D59 Haemolytic anaemias
0.714 0.285 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B65-B83 Helminthiases
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
B15-B19 Viral hepatitis
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
A48 Other bacterial diseases, not elsewhere classified
0.712 0.288 0.000
A44 Bartonellosis
0.712 0.288 0.000
A43 Nocardiosis
0.712 0.288 0.000
A42 Actinomycosis
0.712 0.288 0.000
A39 Meningococcal infection
0.712 0.288 0.000
A37 Whooping cough
0.712 0.288 0.000
A36 Diphtheria
0.712 0.288 0.000
A32 Listeriosis
0.712 0.288 0.000
A31 Infection due to other mycobacteria
0.712 0.288 0.000
A30 Leprosy [Hansen's disease]
0.712 0.288 0.000
A38 Scarlet fever
0.712 0.288 0.000
A35 Other tetanus
0.712 0.288 0.000
A34 Obstetrical tetanus
0.712 0.288 0.000
A33 Tetanus neonatorum
0.712 0.288 0.000
M31 Other necrotising vasculopathies
0.711 0.289 0.000
H52.1 Myopia
0.711 0.289 0.000
S20 Superficial injury of thorax
0.711 0.289 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.711 0.289 0.000
S01.0 Open wound of scalp
0.711 0.289 0.000
Y44 Agents primarily affecting blood constituents
0.711 0.289 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.710 0.290 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
A41.4 Septicaemia due to anaerobes
0.710 0.290 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.710 0.290 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.710 0.290 0.000
A40.8 Other streptococcal septicaemia
0.709 0.291 0.000
M24.5 Contracture of joint
0.709 0.291 0.000
S42.00 Fracture of clavicle (closed)
0.709 0.291 0.000
Z89 Acquired absence of limb
0.708 0.292 0.000
H01 Other inflammation of eyelid
0.708 0.292 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.708 0.292 0.000
D12.7 Rectosigmoid junction
0.708 0.292 0.000
D11 Benign neoplasm of major salivary glands
0.707 0.293 0.000
D06 Carcinoma in situ of cervix uteri
0.707 0.293 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.707 0.293 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.707 0.293 0.000
D32 Benign neoplasm of meninges
0.706 0.294 0.000
Y43 Primarily systemic agents
0.706 0.294 0.000
Z83.7 Family history of diseases of the digestive system
0.706 0.294 0.000
D73 Diseases of spleen
0.706 0.294 0.000
S56 Injury of muscle and tendon at forearm level
0.705 0.295 0.000
D12.3 Transverse colon
0.704 0.296 0.000
Chapter VIII Diseases of the ear and mastoid process
0.704 0.296 0.000
D10 Benign neoplasm of mouth and pharynx
0.703 0.297 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.703 0.297 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.702 0.298 0.000
Z98.1 Arthrodesis status
0.702 0.298 0.000
M24.1 Other articular cartilage disorders
0.702 0.298 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.701 0.299 0.000
C18 Malignant neoplasm of colon
0.700 0.300 0.000
B35-B49 Mycoses
0.700 0.300 0.000
H02.5 Other disorders affecting eyelid function
0.700 0.300 0.000
Z42 Follow-up care involving plastic surgery
0.700 0.300 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.700 0.300 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.699 0.301 0.000
H02.2 Lagophthalmos
0.699 0.301 0.000
H53.9 Visual disturbance, unspecified
0.699 0.301 0.000
D31 Benign neoplasm of eye and adnexa
0.698 0.302 0.000
D30 Benign neoplasm of urinary organs
0.698 0.302 0.000
D29 Benign neoplasm of male genital organs
0.698 0.302 0.000
D26 Other benign neoplasms of uterus
0.698 0.302 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.698 0.302 0.000
D19 Benign neoplasm of mesothelial tissue
0.698 0.302 0.000
D16 Benign neoplasm of bone and articular cartilage
0.698 0.302 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.698 0.302 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.698 0.302 0.000
S50 Superficial injury of forearm
0.697 0.303 0.000
C81 Hodgkin's disease
0.697 0.303 0.000
D23.4 Skin of scalp and neck
0.696 0.304 0.000
M83 Adult osteomalacia
0.696 0.304 0.000
M82 Osteoporosis in diseases classified elsewhere
0.696 0.304 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.696 0.304 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.696 0.304 0.000
H05.2 Exophthalmic conditions
0.695 0.305 0.000
H02.6 Xanthelasma of eyelid
0.694 0.306 0.000
R94 Abnormal results of function studies
0.694 0.306 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.693 0.306 0.000
S42.3 Fracture of shaft of humerus
0.693 0.307 0.000
Y52 Agents primarily affecting the cardiovascular system
0.693 0.307 0.000
D23.0 Skin of lip
0.693 0.307 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.693 0.307 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.693 0.307 0.000
S70-S79 Injuries to the hip and thigh
0.692 0.308 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.692 0.308 0.000
Z84 Family history of other conditions
0.691 0.309 0.000
Z81 Family history of mental and behavioural disorders
0.691 0.309 0.000
S08 Traumatic amputation of part of head
0.691 0.309 0.000
S07 Crushing injury of head
0.691 0.309 0.000
S04 Injury of cranial nerves
0.691 0.309 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.691 0.309 0.000
X60-X84 Intentional self-harm
0.690 0.310 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.690 0.310 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.690 0.310 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.689 0.311 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.689 0.311 0.000
S48 Traumatic amputation of shoulder and upper arm
0.689 0.311 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.689 0.311 0.000
S44 Injury of nerves at shoulder and upper arm level
0.689 0.311 0.000
S41 Open wound of shoulder and upper arm
0.689 0.311 0.000
S47 Crushing injury of shoulder and upper arm
0.689 0.311 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.689 0.311 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.688 0.312 0.000
S01.5 Open wound of lip and oral cavity
0.687 0.313 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.686 0.314 0.000
F30-F39 Mood [affective] disorders
0.685 0.315 0.000
D72 Other disorders of white blood cells
0.684 0.316 0.000
E50-E64 Other nutritional deficiencies
0.684 0.316 0.000
F81 Specific developmental disorders of scholastic skills
0.683 0.316 0.000
M25 Other joint disorders, not elsewhere classified
0.683 0.317 0.000
M20.5 Other deformities of toe(s) (acquired)
0.682 0.317 0.000
Z91.5 Personal history of self-harm
0.682 0.318 0.000
H53.0 Amblyopia ex anopsia
0.682 0.318 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.681 0.318 0.000
L10-L14 Bullous disorders
0.681 0.319 0.000
F60-F69 Disorders of adult personality and behaviour
0.681 0.319 0.000
G30-G32 Other degenerative diseases of the nervous system
0.681 0.319 0.000
C64-C68 Malignant neoplasms of urinary tract
0.680 0.320 0.000
H33 Retinal detachments and breaks
0.680 0.320 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.680 0.320 0.000
D74 Methaemoglobinaemia
0.680 0.320 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.680 0.320 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.680 0.320 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.679 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.679 0.321 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.679 0.321 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.679 0.321 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.321 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.679 0.321 0.000
V80-V89 Other land transport accidents
0.679 0.321 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.677 0.323 0.000
Z93.9 Artificial opening status, unspecified
0.676 0.323 0.000
Z93.8 Other artificial opening status
0.676 0.323 0.000
H18 Other disorders of cornea
0.676 0.324 0.000
Z93.0 Tracheostomy status
0.676 0.324 0.000
C50-C50 Malignant neoplasm of breast
0.676 0.324 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.676 0.324 0.000
Z45 Adjustment and management of implanted device
0.675 0.324 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.675 0.325 0.000
S01.7 Multiple open wounds of head
0.673 0.327 0.000
S01.3 Open wound of ear
0.673 0.327 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.673 0.327 0.000
Y35-Y36 Legal intervention and operations of war
0.673 0.327 0.000
Y10-Y34 Event of undetermined intent
0.673 0.327 0.000
Y00-Y09 Assault
0.673 0.327 0.000
X85-X99 Assault
0.673 0.327 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.673 0.327 0.000
X50-X57 Overexertion, travel and privation
0.673 0.327 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.673 0.327 0.000
X30-X39 Exposure to forces of nature
0.673 0.327 0.000
X10-X19 Contact with heat and hot substances
0.673 0.327 0.000
X00-X09 Exposure to smoke, fire and flames
0.673 0.327 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.673 0.327 0.000
W75-W84 Other accidental threats to breathing
0.673 0.327 0.000
W65-W74 Accidental drowning and submersion
0.673 0.327 0.000
W50-W64 Exposure to animate mechanical forces
0.673 0.327 0.000
V98-V99 Other and unspecified transport accidents
0.673 0.327 0.000
V95-V97 Air and space transport accidents
0.673 0.327 0.000
V90-V94 Water transport accidents
0.673 0.327 0.000
V70-V79 Bus occupant injured in transport accident
0.673 0.327 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.673 0.327 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.673 0.327 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.673 0.327 0.000
V01-V09 Pedestrian injured in transport accident
0.673 0.327 0.000
C18.2 Ascending colon
0.673 0.327 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.672 0.328 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.671 0.329 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.670 0.330 0.000
S01.9 Open wound of head, part unspecified
0.670 0.330 0.000
M23.9 Internal derangement of knee, unspecified
0.670 0.330 0.000
M23.1 Discoid meniscus (congenital)
0.670 0.330 0.000
M23.0 Cystic meniscus
0.670 0.330 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.670 0.330 0.000
Z80.6 Family history of leukaemia
0.670 0.330 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.670 0.330 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.670 0.330 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.669 0.331 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.669 0.331 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.669 0.331 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.669 0.331 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.669 0.331 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.669 0.331 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.668 0.331 0.000
Q80-Q89 Other congenital malformations
0.667 0.333 0.000
D36 Benign neoplasm of other and unspecified sites
0.665 0.335 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.335 0.000
Z86 Personal history of certain other diseases
0.664 0.336 0.000
D23.6 Skin of upper limb, including shoulder
0.664 0.336 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.663 0.337 0.000
M81.4 Drug-induced osteoporosis
0.663 0.337 0.000
A00-A09 Intestinal infectious diseases
0.663 0.337 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.662 0.338 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
L28 Lichen simplex chronicus and prurigo
0.661 0.339 0.000
L25 Unspecified contact dermatitis
0.661 0.339 0.000
L24 Irritant contact dermatitis
0.661 0.339 0.000
L23 Allergic contact dermatitis
0.661 0.339 0.000
L21 Seborrhoeic dermatitis
0.661 0.339 0.000
L20 Atopic dermatitis
0.661 0.339 0.000
L26 Exfoliative dermatitis
0.661 0.339 0.000
L22 Diaper [napkin] dermatitis
0.661 0.339 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.660 0.340 0.000
H51 Other disorders of binocular movement
0.660 0.340 0.000
M72 Fibroblastic disorders
0.660 0.340 0.000
Q60-Q64 Congenital malformations of the urinary system
0.659 0.341 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.658 0.342 0.000
C95 Leukaemia of unspecified cell type
0.658 0.342 0.000
C94 Other leukaemias of specified cell type
0.658 0.342 0.000
C93 Monocytic leukaemia
0.658 0.342 0.000
C88 Malignant immunoproliferative diseases
0.658 0.342 0.000
C86 Other specified types of T/NK-cell lymphoma
0.658 0.342 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.658 0.342 0.000
F03 Unspecified dementia
0.658 0.342 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.658 0.342 0.000
C02.9 Tongue, unspecified
0.657 0.343 0.000
R45 Symptoms and signs involving emotional state
0.656 0.344 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.656 0.344 0.000
C09 Malignant neoplasm of tonsil
0.655 0.345 0.000
S06 Intracranial injury
0.655 0.345 0.000
Z80.3 Family history of malignant neoplasm of breast
0.655 0.345 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.655 0.345 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.655 0.345 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.655 0.345 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.655 0.345 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.655 0.345 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.655 0.345 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.655 0.345 0.000
T36 Poisoning by systemic antibiotics
0.655 0.345 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.654 0.345 0.000
H53.6 Night blindness
0.654 0.346 0.000
H53.5 Colour vision deficiencies
0.654 0.346 0.000
H53.3 Other disorders of binocular vision
0.654 0.346 0.000
M21.0 Valgus deformity, not elsewhere classified
0.654 0.346 0.000
E70-E90 Metabolic disorders
0.653 0.347 0.000
G57.6 Lesion of plantar nerve
0.653 0.347 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.653 0.347 0.000
D12.5 Sigmoid colon
0.652 0.348 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.652 0.348 0.000
D04.3 Skin of other and unspecified parts of face
0.652 0.348 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.652 0.348 0.000
L27 Dermatitis due to substances taken internally
0.651 0.348 0.000
C34.9 Bronchus or lung, unspecified
0.651 0.349 0.000
H43.8 Other disorders of vitreous body
0.650 0.350 0.000
Z43 Attention to artificial openings
0.650 0.350 0.000
M79.6 Pain in limb
0.650 0.350 0.000
S42.4 Fracture of lower end of humerus
0.649 0.351 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.649 0.351 0.000
F70-F79 Mental retardation
0.649 0.351 0.000
M10 Gout
0.649 0.351 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.648 0.352 0.000
D23.3 Skin of other and unspecified parts of face
0.648 0.352 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.647 0.353 0.000
G50 Disorders of trigeminal nerve
0.647 0.353 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.647 0.353 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.646 0.353 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.646 0.353 0.000
H33.3 Retinal breaks without detachment
0.646 0.354 0.000
F25 Schizoaffective disorders
0.645 0.355 0.000
Y59 Other and unspecified vaccines and biological substances
0.645 0.355 0.000
Y58 Bacterial vaccines
0.645 0.355 0.000
Y57 Other and unspecified drugs and medicaments
0.645 0.355 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.645 0.355 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.645 0.355 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.645 0.355 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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