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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78294386
log Bayes Factor = 14.58
Chromosome 12   position 107,963,652  (GRCh37) Explore rs78294386 on Ensembl!
Variant rs78294386 is part of Cluster X0178

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.994 0.006 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.994 0.006 0.000
E10-E14 Diabetes mellitus
0.991 0.009 0.000
I30-I52 Other forms of heart disease
0.990 0.010 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.978 0.022 0.000
I50 Heart failure
0.974 0.026 0.000
W00-W19 Falls
0.972 0.028 0.000
I20-I25 Ischaemic heart diseases
0.971 0.029 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.969 0.031 0.000
E83 Disorders of mineral metabolism
0.969 0.031 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.958 0.042 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.957 0.043 0.000
E14 Unspecified diabetes mellitus
0.953 0.047 0.000
W19 Unspecified fall
0.953 0.047 0.000
S00-S09 Injuries to the head
0.951 0.049 0.000
I50.1 Left ventricular failure
0.949 0.051 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.945 0.055 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.944 0.056 0.000
B95-B98 Bacterial, viral and other infectious agents
0.941 0.059 0.000
D60-D64 Aplastic and other anaemias
0.940 0.060 0.000
E83.5 Disorders of calcium metabolism
0.940 0.060 0.000
Chapter X Diseases of the respiratory system
0.940 0.060 0.000
Chapter V Mental and behavioural disorders
0.939 0.061 0.000
W19.9 Unspecified place
0.938 0.062 0.000
M80-M85 Disorders of bone density and structure
0.936 0.064 0.000
Chapter XI Diseases of the digestive system
0.931 0.069 0.000
E14.9 Without complications
0.927 0.073 0.000
K90-K93 Other diseases of the digestive system
0.924 0.076 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.922 0.078 0.000
K92 Other diseases of digestive system
0.922 0.078 0.000
C50-C50 Malignant neoplasm of breast
0.921 0.079 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.917 0.083 0.000
D64 Other anaemias
0.915 0.085 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.904 0.096 0.000
C78.7 Secondary malignant neoplasm of liver
0.902 0.098 0.000
S01 Open wound of head
0.901 0.099 0.000
C78.0 Secondary malignant neoplasm of lung
0.900 0.100 0.000
M81 Osteoporosis without pathological fracture
0.900 0.100 0.000
E78.5 Hyperlipidaemia, unspecified
0.899 0.101 0.000
J30-J39 Other diseases of upper respiratory tract
0.899 0.101 0.000
I20 Angina pectoris
0.897 0.103 0.000
D64.9 Anaemia, unspecified
0.897 0.103 0.000
K92.1 Melaena
0.896 0.104 0.000
E11 Non-insulin-dependent diabetes mellitus
0.895 0.105 0.000
C79 Secondary malignant neoplasm of other sites
0.895 0.105 0.000
W20-W49 Exposure to inanimate mechanical forces
0.892 0.108 0.000
I51 Complications and ill-defined descriptions of heart disease
0.891 0.109 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.885 0.115 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.885 0.115 0.000
K92.0 Haematemesis
0.882 0.118 0.000
I50.0 Congestive heart failure
0.882 0.118 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.875 0.125 0.000
M15-M19 Arthrosis
0.875 0.125 0.000
M81.9 Osteoporosis, unspecified
0.874 0.126 0.000
C15-C26 Malignant neoplasms of digestive organs
0.872 0.128 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.870 0.130 0.000
C50 Malignant neoplasm of breast
0.864 0.136 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.864 0.136 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.863 0.137 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.862 0.138 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.858 0.142 0.000
T66-T78 Other and unspecified effects of external causes
0.857 0.142 0.000
E10 Insulin-dependent diabetes mellitus
0.854 0.146 0.000
K70-K77 Diseases of liver
0.853 0.147 0.000
R00 Abnormalities of heart beat
0.852 0.148 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.848 0.152 0.000
R06 Abnormalities of breathing
0.848 0.152 0.000
R04 Haemorrhage from respiratory passages
0.847 0.153 0.000
Y43 Primarily systemic agents
0.847 0.153 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.846 0.154 0.000
M70-M79 Other soft tissue disorders
0.838 0.162 0.000
E11.9 Without complications
0.838 0.162 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.830 0.170 0.000
I20.0 Unstable angina
0.827 0.173 0.000
C50.4 Upper-outer quadrant of breast
0.826 0.174 0.000
S01.8 Open wound of other parts of head
0.825 0.175 0.000
D10-D36 Benign neoplasms
0.822 0.178 0.000
I25 Chronic ischaemic heart disease
0.822 0.178 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.819 0.181 0.000
S50-S59 Injuries to the elbow and forearm
0.815 0.185 0.000
D00-D09 In situ neoplasms
0.814 0.186 0.000
E87.7 Fluid overload
0.813 0.187 0.000
E83.3 Disorders of phosphorus metabolism
0.807 0.193 0.000
I30 Acute pericarditis
0.807 0.193 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.807 0.193 0.000
S40-S49 Injuries to the shoulder and upper arm
0.807 0.193 0.000
K01 Embedded and impacted teeth
0.806 0.194 0.000
B35-B49 Mycoses
0.803 0.197 0.000
D61 Other aplastic anaemias
0.801 0.199 0.000
Y40 Systemic antibiotics
0.800 0.200 0.000
A00-A09 Intestinal infectious diseases
0.799 0.201 0.000
J00-J06 Acute upper respiratory infections
0.798 0.202 0.000
I31 Other diseases of pericardium
0.798 0.202 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.797 0.203 0.000
W22 Striking against or struck by other objects
0.797 0.203 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.796 0.204 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.796 0.204 0.000
W19.2 School, other institution and public administrative area
0.795 0.205 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.793 0.207 0.000
M86-M90 Other osteopathies
0.790 0.210 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.789 0.211 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.789 0.211 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.788 0.212 0.000
R42 Dizziness and giddiness
0.787 0.213 0.000
I46 Cardiac arrest
0.787 0.213 0.000
S06 Intracranial injury
0.782 0.218 0.000
C77.4 Inguinal and lower limb lymph nodes
0.781 0.219 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.779 0.221 0.000
B15-B19 Viral hepatitis
0.777 0.223 0.000
I24 Other acute ischaemic heart diseases
0.775 0.225 0.000
E87.5 Hyperkalaemia
0.774 0.226 0.000
R01 Cardiac murmurs and other cardiac sounds
0.772 0.228 0.000
I51.9 Heart disease, unspecified
0.771 0.229 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.770 0.230 0.000
Y57 Other and unspecified drugs and medicaments
0.769 0.231 0.000
Y43.3 Other antineoplastic drugs
0.767 0.233 0.000
A30-A49 Other bacterial diseases
0.766 0.234 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.765 0.235 0.000
K01.1 Impacted teeth
0.765 0.235 0.000
M17 Gonarthrosis [arthrosis of knee]
0.764 0.236 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.764 0.236 0.000
I25.1 Atherosclerotic heart disease
0.763 0.237 0.000
I49 Other cardiac arrhythmias
0.762 0.237 0.000
J95-J99 Other diseases of the respiratory system
0.762 0.238 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.760 0.240 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.760 0.240 0.000
E10.9 Without complications
0.759 0.241 0.000
S70-S79 Injuries to the hip and thigh
0.758 0.241 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.758 0.242 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.758 0.242 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.757 0.243 0.000
T78 Adverse effects, not elsewhere classified
0.757 0.243 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.757 0.243 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.756 0.244 0.000
S60-S69 Injuries to the wrist and hand
0.755 0.245 0.000
I95 Hypotension
0.754 0.246 0.000
C78.2 Secondary malignant neoplasm of pleura
0.754 0.246 0.000
X60-X84 Intentional self-harm
0.752 0.248 0.000
S90-S99 Injuries to the ankle and foot
0.752 0.248 0.000
M05-M14 Inflammatory polyarthropathies
0.752 0.248 0.000
I21 Acute myocardial infarction
0.751 0.249 0.000
F99-F99 Unspecified mental disorder
0.750 0.250 0.000
I20.1 Angina pectoris with documented spasm
0.750 0.250 0.000
R00.0 Tachycardia, unspecified
0.750 0.250 0.000
C51-C58 Malignant neoplasms of female genital organs
0.749 0.251 0.000
I80 Phlebitis and thrombophlebitis
0.747 0.253 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.747 0.253 0.000
I20.8 Other forms of angina pectoris
0.744 0.256 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.743 0.257 0.000
M91-M94 Chondropathies
0.741 0.258 0.000
R04.0 Epistaxis
0.741 0.259 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.741 0.259 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.740 0.260 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.740 0.260 0.000
D25 Leiomyoma of uterus
0.740 0.260 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.739 0.261 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.739 0.261 0.000
I51.8 Other ill-defined heart diseases
0.738 0.262 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.738 0.262 0.000
F60-F69 Disorders of adult personality and behaviour
0.737 0.263 0.000
J30 Vasomotor and allergic rhinitis
0.736 0.264 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.734 0.265 0.000
S00 Superficial injury of head
0.734 0.266 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.733 0.267 0.000
R94 Abnormal results of function studies
0.733 0.267 0.000
V20-V29 Motorcycle rider injured in transport accident
0.732 0.268 0.000
M75 Shoulder lesions
0.731 0.269 0.000
K76 Other diseases of liver
0.731 0.269 0.000
E11.4 With neurological complications
0.729 0.271 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.729 0.271 0.000
W22.9 Unspecified place
0.729 0.271 0.000
S01.5 Open wound of lip and oral cavity
0.727 0.272 0.000
R06.0 Dyspnoea
0.727 0.273 0.000
R50-R69 General symptoms and signs
0.727 0.273 0.000
I73 Other peripheral vascular diseases
0.726 0.274 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.726 0.274 0.000
C15 Malignant neoplasm of oesophagus
0.726 0.274 0.000
D62 Acute posthaemorrhagic anaemia
0.726 0.274 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.724 0.275 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.724 0.276 0.000
J34 Other disorders of nose and nasal sinuses
0.723 0.277 0.000
D06 Carcinoma in situ of cervix uteri
0.722 0.278 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.722 0.278 0.000
C77.2 Intra-abdominal lymph nodes
0.721 0.279 0.000
R21 Rash and other nonspecific skin eruption
0.721 0.279 0.000
C80 Malignant neoplasm without specification of site
0.721 0.279 0.000
M40-M43 Deforming dorsopathies
0.721 0.279 0.000
F30-F39 Mood [affective] disorders
0.719 0.281 0.000
I22 Subsequent myocardial infarction
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C77.1 Intrathoracic lymph nodes
0.716 0.283 0.000
E40-E46 Malnutrition
0.716 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
C77.9 Lymph node, unspecified
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.284 0.000
Y00-Y09 Assault
0.715 0.284 0.000
X85-X99 Assault
0.715 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.284 0.000
X50-X57 Overexertion, travel and privation
0.715 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.284 0.000
X30-X39 Exposure to forces of nature
0.715 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.284 0.000
X10-X19 Contact with heat and hot substances
0.715 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.284 0.000
W75-W84 Other accidental threats to breathing
0.715 0.284 0.000
W65-W74 Accidental drowning and submersion
0.715 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.284 0.000
V95-V97 Air and space transport accidents
0.715 0.284 0.000
V90-V94 Water transport accidents
0.715 0.284 0.000
V80-V89 Other land transport accidents
0.715 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.284 0.000
S02 Fracture of skull and facial bones
0.715 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
M80 Osteoporosis with pathological fracture
0.714 0.286 0.000
Y44 Agents primarily affecting blood constituents
0.713 0.287 0.000
E88 Other metabolic disorders
0.713 0.287 0.000
E85 Amyloidosis
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.713 0.287 0.000
E73 Lactose intolerance
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.712 0.287 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.712 0.287 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.712 0.287 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.712 0.288 0.000
I10-I15 Hypertensive diseases
0.710 0.290 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
E13 Other specified diabetes mellitus
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.710 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.710 0.290 0.000
I48 Atrial fibrillation and flutter
0.710 0.290 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.710 0.290 0.000
I41 Myocarditis in diseases classified elsewhere
0.710 0.290 0.000
I40 Acute myocarditis
0.710 0.290 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.710 0.290 0.000
I37 Pulmonary valve disorders
0.710 0.290 0.000
I36 Nonrheumatic tricuspid valve disorders
0.710 0.290 0.000
I33 Acute and subacute endocarditis
0.710 0.290 0.000
I32 Pericarditis in diseases classified elsewhere
0.710 0.290 0.000
D80-D89 Certain disorders involving the immune mechanism
0.709 0.291 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.709 0.291 0.000
C34 Malignant neoplasm of bronchus and lung
0.709 0.291 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A80-A89 Viral infections of the central nervous system
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
M16 Coxarthrosis [arthrosis of hip]
0.707 0.293 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.706 0.293 0.000
S01.0 Open wound of scalp
0.707 0.293 0.000
I44 Atrioventricular and left bundle-branch block
0.706 0.294 0.000
O60-O75 Complications of labour and delivery
0.706 0.294 0.000
M84 Disorders of continuity of bone
0.706 0.294 0.000
D25.9 Leiomyoma of uterus, unspecified
0.706 0.294 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.705 0.295 0.000
E50-E64 Other nutritional deficiencies
0.705 0.295 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.705 0.295 0.000
S01.1 Open wound of eyelid and periocular area
0.704 0.296 0.000
D23 Other benign neoplasms of skin
0.704 0.296 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.703 0.297 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.702 0.298 0.000
Chapter XXII Codes for special purposes
0.702 0.298 0.000
D61.9 Aplastic anaemia, unspecified
0.702 0.298 0.000
E83.4 Disorders of magnesium metabolism
0.701 0.299 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.701 0.299 0.000
R00.1 Bradycardia, unspecified
0.700 0.299 0.000
F80-F89 Disorders of psychological development
0.700 0.300 0.000
J35 Chronic diseases of tonsils and adenoids
0.700 0.300 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.700 0.300 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.699 0.301 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.698 0.302 0.000
W18 Other fall on same level
0.697 0.303 0.000
W17 Other fall from one level to another
0.697 0.303 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.697 0.303 0.000
W15 Fall from cliff
0.697 0.303 0.000
W14 Fall from tree
0.697 0.303 0.000
W13 Fall from, out of or through building or structure
0.697 0.303 0.000
W12 Fall on and from scaffolding
0.697 0.303 0.000
W11 Fall on and from ladder
0.697 0.303 0.000
W10 Fall on and from stairs and steps
0.697 0.303 0.000
W09 Fall involving playground equipment
0.697 0.303 0.000
W08 Fall involving other furniture
0.697 0.303 0.000
W07 Fall involving chair
0.697 0.303 0.000
W06 Fall involving bed
0.697 0.303 0.000
W05 Fall involving wheelchair
0.697 0.303 0.000
W04 Fall while being carried or supported by other persons
0.697 0.303 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.697 0.303 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.697 0.303 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.697 0.303 0.000
W00 Fall on same level involving ice and snow
0.697 0.303 0.000
M18 Arthrosis of first carpometacarpal joint
0.696 0.304 0.000
I23 Certain current complications following acute myocardial infarction
0.696 0.304 0.000
M85 Other disorders of bone density and structure
0.696 0.304 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.695 0.304 0.000
M60-M63 Disorders of muscles
0.695 0.305 0.000
M00-M03 Infectious arthropathies
0.695 0.305 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.695 0.305 0.000
E83.8 Other disorders of mineral metabolism
0.695 0.305 0.000
E83.2 Disorders of zinc metabolism
0.695 0.305 0.000
E83.0 Disorders of copper metabolism
0.695 0.305 0.000
I25.2 Old myocardial infarction
0.694 0.306 0.000
V10-V19 Pedal cyclist injured in transport accident
0.694 0.306 0.000
W25 Contact with sharp glass
0.693 0.307 0.000
I35 Nonrheumatic aortic valve disorders
0.693 0.307 0.000
R04.2 Haemoptysis
0.692 0.308 0.000
J39 Other diseases of upper respiratory tract
0.691 0.309 0.000
C50.2 Upper-inner quadrant of breast
0.690 0.310 0.000
I77 Other disorders of arteries and arterioles
0.690 0.310 0.000
E87.0 Hyperosmolality and hypernatraemia
0.690 0.310 0.000
J02 Acute pharyngitis
0.690 0.310 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.689 0.311 0.000
A04 Other bacterial intestinal infections
0.689 0.311 0.000
Chapter VI Diseases of the nervous system
0.688 0.312 0.000
R23 Other skin changes
0.688 0.312 0.000
Y59 Other and unspecified vaccines and biological substances
0.687 0.313 0.000
Y58 Bacterial vaccines
0.687 0.313 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.687 0.313 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.313 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.687 0.313 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.687 0.313 0.000
Y52 Agents primarily affecting the cardiovascular system
0.687 0.313 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.687 0.313 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.687 0.313 0.000
Y48 Anaesthetics and therapeutic gases
0.687 0.313 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.687 0.313 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.687 0.313 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.687 0.313 0.000
D55-D59 Haemolytic anaemias
0.686 0.314 0.000
K12 Stomatitis and related lesions
0.685 0.315 0.000
J90-J94 Other diseases of pleura
0.685 0.315 0.000
I85 Oesophageal varices
0.684 0.316 0.000
E14.8 With unspecified complications
0.684 0.316 0.000
E14.7 With multiple complications
0.684 0.316 0.000
E14.6 With other specified complications
0.684 0.316 0.000
E14.5 With peripheral circulatory complications
0.684 0.316 0.000
E14.4 With neurological complications
0.684 0.316 0.000
E14.2 Withrenal complications
0.684 0.316 0.000
E14.1 With ketoacidosis
0.684 0.316 0.000
E14.0 With coma
0.684 0.316 0.000
W19.8 Other specified place
0.683 0.316 0.000
W19.5 Trade and service area
0.683 0.316 0.000
W19.0 Home
0.683 0.316 0.000
W19.7 Farm
0.683 0.316 0.000
W19.6 Industrial and construction area
0.683 0.316 0.000
W19.3 Sports and athletics area
0.683 0.316 0.000
W19.1 Residential institution
0.683 0.316 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.683 0.317 0.000
K08 Other disorders of teeth and supporting structures
0.682 0.318 0.000
S08 Traumatic amputation of part of head
0.682 0.318 0.000
S07 Crushing injury of head
0.682 0.318 0.000
S05 Injury of eye and orbit
0.682 0.318 0.000
S04 Injury of cranial nerves
0.682 0.318 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.682 0.318 0.000
S20-S29 Injuries to the thorax
0.681 0.319 0.000
I45 Other conduction disorders
0.681 0.319 0.000
D13.1 Stomach
0.680 0.319 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.680 0.320 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.678 0.322 0.000
E14.3 With ophthalmic complications
0.678 0.322 0.000
R06.5 Mouth breathing
0.677 0.323 0.000
R60 Oedema, not elsewhere classified
0.677 0.323 0.000
I30.1 Infective pericarditis
0.676 0.324 0.000
I21.9 Acute myocardial infarction, unspecified
0.675 0.325 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.675 0.325 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.675 0.325 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.674 0.326 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.673 0.327 0.000
F70-F79 Mental retardation
0.673 0.327 0.000
S51 Open wound of forearm
0.672 0.328 0.000
J38.7 Other diseases of larynx
0.672 0.328 0.000
K09 Cysts of oral region, not elsewhere classified
0.671 0.329 0.000
B37 Candidiasis
0.671 0.329 0.000
M83 Adult osteomalacia
0.671 0.329 0.000
M82 Osteoporosis in diseases classified elsewhere
0.671 0.329 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.671 0.329 0.000
I72 Other aneurysm
0.671 0.329 0.000
K74 Fibrosis and cirrhosis of liver
0.670 0.330 0.000
R02 Gangrene, not elsewhere classified
0.669 0.331 0.000
E83.1 Disorders of iron metabolism
0.669 0.331 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.669 0.331 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.668 0.332 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.668 0.332 0.000
K70 Alcoholic liver disease
0.667 0.333 0.000
I38 Endocarditis, valve unspecified
0.666 0.334 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.665 0.335 0.000
M75.4 Impingement syndrome of shoulder
0.665 0.335 0.000
I86 Varicose veins of other sites
0.664 0.336 0.000
K75 Other inflammatory liver diseases
0.664 0.336 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.664 0.336 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.663 0.337 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.662 0.338 0.000
R47-R49 Symptoms and signs involving speech and voice
0.662 0.338 0.000
Y40.9 Systemic antibiotic, unspecified
0.661 0.339 0.000
E78.8 Other disorders of lipoprotein metabolism
0.661 0.339 0.000
E78.6 Lipoprotein deficiency
0.661 0.339 0.000
E78.4 Other hyperlipidaemia
0.661 0.339 0.000
E78.3 Hyperchylomicronaemia
0.661 0.339 0.000
E78.2 Mixed hyperlipidaemia
0.661 0.339 0.000
E78.1 Pure hyperglyceridaemia
0.661 0.339 0.000
K92.9 Disease of digestive system, unspecified
0.661 0.339 0.000
K92.8 Other specified diseases of digestive system
0.661 0.339 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.660 0.340 0.000
M17.0 Primary gonarthrosis, bilateral
0.659 0.341 0.000
D34 Benign neoplasm of thyroid gland
0.658 0.342 0.000
E10.1 With ketoacidosis
0.658 0.342 0.000
J33 Nasal polyp
0.658 0.342 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.658 0.342 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.658 0.342 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.658 0.342 0.000
S01.2 Open wound of nose
0.657 0.342 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.657 0.343 0.000
D06.9 Cervix, unspecified
0.657 0.343 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.656 0.344 0.000
D64.8 Other specified anaemias
0.656 0.344 0.000
D64.4 Congenital dyserythropoietic anaemia
0.656 0.344 0.000
D64.3 Other sideroblastic anaemias
0.656 0.344 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.656 0.344 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.656 0.344 0.000
D64.0 Hereditary sideroblastic anaemia
0.656 0.344 0.000
I73.9 Peripheral vascular disease, unspecified
0.656 0.344 0.000
E87.2 Acidosis
0.655 0.344 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.654 0.346 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.654 0.346 0.000
S60 Superficial injury of wrist and hand
0.654 0.346 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.653 0.347 0.000
C50.3 Lower-inner quadrant of breast
0.652 0.348 0.000
C25 Malignant neoplasm of pancreas
0.651 0.349 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.650 0.350 0.000
E20-E35 Disorders of other endocrine glands
0.649 0.350 0.000
R01.1 Cardiac murmur, unspecified
0.649 0.351 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.649 0.351 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.648 0.352 0.000
T87 Complications peculiar to reattachment and amputation
0.648 0.352 0.000
T86 Failure and rejection of transplanted organs and tissues
0.648 0.352 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.648 0.352 0.000
S01.7 Multiple open wounds of head
0.646 0.354 0.000
S01.4 Open wound of cheek and temporomandibular area
0.646 0.354 0.000
S01.3 Open wound of ear
0.646 0.354 0.000
T78.3 Angioneurotic oedema
0.646 0.354 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.645 0.354 0.000
M81.8 Other osteoporosis
0.645 0.355 0.000
M81.6 Localised osteoporosis [Lequesne]
0.645 0.355 0.000
M81.5 Idiopathic osteoporosis
0.645 0.355 0.000
M81.4 Drug-induced osteoporosis
0.645 0.355 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.645 0.355 0.000
M81.2 Osteoporosis of disuse
0.645 0.355 0.000
M81.1 Postoophorectomy osteoporosis
0.645 0.355 0.000
M81.0 Postmenopausal osteoporosis
0.645 0.355 0.000
Y40.8 Other systemic antibiotics
0.645 0.355 0.000
I51.7 Cardiomegaly
0.645 0.355 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.645 0.355 0.000
J37 Chronic laryngitis and laryngotracheitis
0.645 0.355 0.000
I31.9 Disease of pericardium, unspecified
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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