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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78333854
log Bayes Factor = 12.5594
Chromosome 13   position 38,718,163  (GRCh37) Explore rs78333854 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
Chapter II Neoplasms
0.992 0.008 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.987 0.013 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.986 0.014 0.000
M15-M19 Arthrosis
0.985 0.015 0.000
M20-M25 Other joint disorders
0.979 0.021 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.973 0.027 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.973 0.027 0.000
Chapter XI Diseases of the digestive system
0.967 0.033 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.964 0.036 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.963 0.037 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.951 0.049 0.000
K90-K93 Other diseases of the digestive system
0.948 0.052 0.000
K40-K46 Hernia
0.947 0.053 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.946 0.054 0.000
M25 Other joint disorders, not elsewhere classified
0.940 0.060 0.000
I67 Other cerebrovascular diseases
0.937 0.063 0.000
I73 Other peripheral vascular diseases
0.933 0.067 0.000
I77 Other disorders of arteries and arterioles
0.933 0.067 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.931 0.069 0.000
E70-E90 Metabolic disorders
0.931 0.069 0.000
Z92 Personal history of medical treatment
0.931 0.069 0.000
C51-C58 Malignant neoplasms of female genital organs
0.928 0.072 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.927 0.073 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.926 0.074 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.924 0.076 0.000
K42 Umbilical hernia
0.922 0.078 0.000
Z72 Problems related to lifestyle
0.921 0.079 0.000
C77.3 Axillary and upper limb lymph nodes
0.920 0.080 0.000
K70-K77 Diseases of liver
0.919 0.081 0.000
K43 Ventral hernia
0.918 0.082 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.914 0.086 0.000
S60-S69 Injuries to the wrist and hand
0.906 0.094 0.000
I63 Cerebral infarction
0.902 0.098 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.901 0.099 0.000
W00-W19 Falls
0.901 0.099 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.901 0.099 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.901 0.099 0.000
Z96 Presence of other functional implants
0.900 0.100 0.000
S20-S29 Injuries to the thorax
0.898 0.102 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.898 0.102 0.000
I10-I15 Hypertensive diseases
0.896 0.104 0.000
Z72.1 Alcohol use
0.896 0.104 0.000
M19 Other arthrosis
0.893 0.107 0.000
Z73 Problems related to life-management difficulty
0.890 0.110 0.000
I95 Hypotension
0.890 0.110 0.000
M18 Arthrosis of first carpometacarpal joint
0.889 0.111 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.885 0.115 0.000
Z93 Artificial opening status
0.883 0.117 0.000
M22 Disorders of patella
0.883 0.117 0.000
M45-M49 Spondylopathies
0.881 0.119 0.000
Z57 Occupational exposure to risk-factors
0.881 0.119 0.000
I61 Intracerebral haemorrhage
0.880 0.120 0.000
T66-T78 Other and unspecified effects of external causes
0.880 0.120 0.000
I60 Subarachnoid haemorrhage
0.879 0.121 0.000
E86 Volume depletion
0.877 0.123 0.000
Chapter XIV Diseases of the genitourinary system
0.875 0.125 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.874 0.126 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.874 0.126 0.000
C77.5 Intrapelvic lymph nodes
0.873 0.127 0.000
I69 Sequelae of cerebrovascular disease
0.873 0.127 0.000
I62 Other nontraumatic intracranial haemorrhage
0.873 0.127 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.870 0.130 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.867 0.133 0.000
Y95 Nosocomial condition
0.860 0.140 0.000
D48.5 Skin
0.859 0.141 0.000
I74 Arterial embolism and thrombosis
0.859 0.141 0.000
I95.9 Hypotension, unspecified
0.854 0.146 0.000
M19.9 Arthrosis, unspecified
0.854 0.146 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.850 0.150 0.000
Z89 Acquired absence of limb
0.849 0.151 0.000
I12 Hypertensive renal disease
0.847 0.153 0.000
K91.4 Colostomy and enterostomy malfunction
0.846 0.154 0.000
Y86 Sequelae of other accidents
0.843 0.157 0.000
E83 Disorders of mineral metabolism
0.841 0.159 0.000
I67.9 Cerebrovascular disease, unspecified
0.838 0.162 0.000
I73.9 Peripheral vascular disease, unspecified
0.838 0.162 0.000
K92 Other diseases of digestive system
0.837 0.163 0.000
I67.1 Cerebral aneurysm, nonruptured
0.833 0.167 0.000
Z96.6 Presence of orthopaedic joint implants
0.832 0.168 0.000
M16 Coxarthrosis [arthrosis of hip]
0.832 0.168 0.000
I30-I52 Other forms of heart disease
0.831 0.169 0.000
N17-N19 Renal failure
0.829 0.171 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.828 0.172 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.828 0.172 0.000
C77.9 Lymph node, unspecified
0.825 0.175 0.000
K75 Other inflammatory liver diseases
0.823 0.177 0.000
D48.1 Connective and other soft tissue
0.822 0.178 0.000
C53 Malignant neoplasm of cervix uteri
0.820 0.180 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.818 0.182 0.000
M17 Gonarthrosis [arthrosis of knee]
0.818 0.182 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.818 0.182 0.000
S68 Traumatic amputation of wrist and hand
0.817 0.183 0.000
I12.0 Hypertensive renal disease with renal failure
0.816 0.184 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.816 0.184 0.000
I73.0 Raynaud's syndrome
0.816 0.184 0.000
C56 Malignant neoplasm of ovary
0.815 0.185 0.000
M25.3 Other instability of joint
0.814 0.186 0.000
Z57.2 Occupational exposure to dust
0.812 0.188 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.812 0.188 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.810 0.190 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.807 0.193 0.000
E87.7 Fluid overload
0.806 0.194 0.000
M91-M94 Chondropathies
0.806 0.194 0.000
Chapter VII Diseases of the eye and adnexa
0.806 0.194 0.000
Z88.5 Personal history of allergy to narcotic agent
0.805 0.195 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.804 0.196 0.000
Z96.0 Presence of urogenital implants
0.804 0.196 0.000
Z59 Problems related to housing and economic circumstances
0.803 0.197 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.803 0.197 0.000
X60-X84 Intentional self-harm
0.803 0.197 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.801 0.199 0.000
M46 Other inflammatory spondylopathies
0.801 0.199 0.000
T78 Adverse effects, not elsewhere classified
0.797 0.203 0.000
N40-N51 Diseases of male genital organs
0.797 0.203 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.797 0.203 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.796 0.204 0.000
S80-S89 Injuries to the knee and lower leg
0.795 0.205 0.000
S61 Open wound of wrist and hand
0.795 0.205 0.000
S40-S49 Injuries to the shoulder and upper arm
0.794 0.206 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.792 0.208 0.000
I71 Aortic aneurysm and dissection
0.792 0.208 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.792 0.208 0.000
Z75 Problems related to medical facilities and other health care
0.792 0.208 0.000
K76 Other diseases of liver
0.792 0.208 0.000
I50 Heart failure
0.791 0.209 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.789 0.211 0.000
Z60 Problems related to social environment
0.788 0.212 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.787 0.213 0.000
M25.5 Pain in joint
0.785 0.215 0.000
M35 Other systemic involvement of connective tissue
0.784 0.216 0.000
M24 Other specific joint derangements
0.783 0.217 0.000
E83.4 Disorders of magnesium metabolism
0.782 0.218 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.782 0.218 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.782 0.218 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.781 0.219 0.000
I77.8 Other specified disorders of arteries and arterioles
0.780 0.220 0.000
Z22 Carrier of infectious disease
0.779 0.221 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.779 0.221 0.000
E20-E35 Disorders of other endocrine glands
0.779 0.221 0.000
M50-M54 Other dorsopathies
0.778 0.222 0.000
K85 Acute pancreatitis
0.778 0.222 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.776 0.224 0.000
S00-S09 Injuries to the head
0.775 0.225 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.775 0.225 0.000
T14 Injury of unspecified body region
0.774 0.226 0.000
C80 Malignant neoplasm without specification of site
0.772 0.228 0.000
N17 Acute renal failure
0.772 0.228 0.000
Z88.6 Personal history of allergy to analgesic agent
0.772 0.228 0.000
K91.1 Postgastric surgery syndromes
0.770 0.230 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.767 0.233 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.766 0.234 0.000
V40-V49 Car occupant injured in transport accident
0.765 0.235 0.000
I77.0 Arteriovenous fistula, acquired
0.764 0.236 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.764 0.236 0.000
I63.9 Cerebral infarction, unspecified
0.763 0.237 0.000
W20-W49 Exposure to inanimate mechanical forces
0.762 0.238 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.759 0.241 0.000
N10-N16 Renal tubulo-interstitial diseases
0.758 0.242 0.000
M21 Other acquired deformities of limbs
0.756 0.244 0.000
Z71.8 Other specified counselling
0.756 0.244 0.000
M25.9 Joint disorder, unspecified
0.755 0.245 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.755 0.245 0.000
C77.2 Intra-abdominal lymph nodes
0.754 0.246 0.000
C79 Secondary malignant neoplasm of other sites
0.754 0.246 0.000
I50.0 Congestive heart failure
0.754 0.246 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.754 0.246 0.000
K86 Other diseases of pancreas
0.753 0.247 0.000
Z95.2 Presence of prosthetic heart valve
0.753 0.247 0.000
Z84 Family history of other conditions
0.752 0.247 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.751 0.249 0.000
M22.2 Patellofemoral disorders
0.751 0.249 0.000
Z63 Other problems related to primary support group, including family circumstances
0.750 0.250 0.000
M25.57 Pain in joint (Ankle and foot)
0.750 0.250 0.000
E50-E64 Other nutritional deficiencies
0.749 0.251 0.000
M34 Systemic sclerosis
0.749 0.251 0.000
W10 Fall on and from stairs and steps
0.749 0.251 0.000
Z81 Family history of mental and behavioural disorders
0.748 0.252 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.747 0.253 0.000
M25.0 Haemarthrosis
0.747 0.253 0.000
I63.8 Other cerebral infarction
0.747 0.253 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.746 0.254 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.746 0.254 0.000
Z96.7 Presence of other bone and tendon implants
0.745 0.255 0.000
K85.9 Acute pancreatitis, unspecified
0.745 0.255 0.000
Z88.2 Personal history of allergy to sulphonamides
0.745 0.255 0.000
D00-D09 In situ neoplasms
0.745 0.255 0.000
D45 Polycythaemia vera
0.744 0.256 0.000
V20-V29 Motorcycle rider injured in transport accident
0.744 0.256 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.743 0.256 0.000
C53.9 Cervix uteri, unspecified
0.743 0.257 0.000
Z93.6 Other artificial openings of urinary tract status
0.741 0.259 0.000
S20 Superficial injury of thorax
0.741 0.259 0.000
Chapter VIII Diseases of the ear and mastoid process
0.740 0.260 0.000
M25.7 Osteophyte
0.739 0.260 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.739 0.260 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.736 0.264 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.735 0.265 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.735 0.265 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.734 0.266 0.000
N17.9 Acute renal failure, unspecified
0.731 0.269 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.730 0.270 0.000
D48.0 Bone and articular cartilage
0.730 0.270 0.000
Z99.3 Dependence on wheelchair
0.730 0.270 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.729 0.271 0.000
T79-T79 Certain early complications of trauma
0.728 0.272 0.000
C77.0 Lymph nodes of head, face and neck
0.728 0.272 0.000
M65-M68 Disorders of synovium and tendon
0.727 0.273 0.000
Z95.4 Presence of other heart-valve replacement
0.725 0.275 0.000
M86-M90 Other osteopathies
0.724 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.724 0.276 0.000
M22.8 Other disorders of patella
0.724 0.276 0.000
M25.36 Other instability of joint (Lower leg)
0.723 0.277 0.000
Z94 Transplanted organ and tissue status
0.723 0.277 0.000
M25.4 Effusion of joint
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.723 0.277 0.000
K75.8 Other specified inflammatory liver diseases
0.721 0.279 0.000
W19 Unspecified fall
0.721 0.279 0.000
Z71.9 Counselling, unspecified
0.720 0.280 0.000
M00-M03 Infectious arthropathies
0.718 0.282 0.000
Q50-Q56 Congenital malformations of genital organs
0.717 0.283 0.000
Q80-Q89 Other congenital malformations
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
I70 Atherosclerosis
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
M47 Spondylosis
0.713 0.287 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.712 0.287 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.288 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.711 0.289 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.711 0.289 0.000
K74 Fibrosis and cirrhosis of liver
0.710 0.290 0.000
Z92.8 Personal history of other medical treatment
0.709 0.291 0.000
Z89.4 Acquired absence of foot and ankle
0.709 0.291 0.000
T14.0 Superficial injury of unspecified body region
0.708 0.292 0.000
Z97 Presence of other devices
0.708 0.292 0.000
Z76 Persons encountering health services in other circumstances
0.708 0.292 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.708 0.292 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.707 0.293 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.707 0.293 0.000
N50 Other disorders of male genital organs
0.707 0.293 0.000
M15 Polyarthrosis
0.706 0.294 0.000
I81 Portal vein thrombosis
0.705 0.295 0.000
K45 Other abdominal hernia
0.705 0.295 0.000
Z90.1 Acquired absence of breast(s)
0.705 0.295 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.705 0.295 0.000
C78.0 Secondary malignant neoplasm of lung
0.705 0.295 0.000
V10-V19 Pedal cyclist injured in transport accident
0.704 0.296 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.704 0.296 0.000
C77.4 Inguinal and lower limb lymph nodes
0.703 0.296 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.703 0.297 0.000
Chapter XXII Codes for special purposes
0.702 0.297 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.702 0.298 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.702 0.298 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.702 0.298 0.000
M33 Dermatopolymyositis
0.702 0.298 0.000
M32 Systemic lupus erythematosus
0.702 0.298 0.000
M30 Polyarteritis nodosa and related conditions
0.702 0.298 0.000
I77.1 Stricture of artery
0.701 0.299 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.701 0.299 0.000
S06 Intracranial injury
0.701 0.299 0.000
K92.1 Melaena
0.700 0.300 0.000
I74.5 Embolism and thrombosis of iliac artery
0.700 0.300 0.000
W06 Fall involving bed
0.700 0.300 0.000
W08 Fall involving other furniture
0.699 0.301 0.000
M16.0 Primary coxarthrosis, bilateral
0.698 0.302 0.000
Q21 Congenital malformations of cardiac septa
0.698 0.302 0.000
H02 Other disorders of eyelid
0.698 0.302 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.698 0.302 0.000
I77.6 Arteritis, unspecified
0.697 0.303 0.000
K73 Chronic hepatitis, not elsewhere classified
0.697 0.303 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.696 0.304 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.696 0.304 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.696 0.304 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.694 0.306 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.694 0.306 0.000
Z29 Need for other prophylactic measures
0.693 0.307 0.000
M17.9 Gonarthrosis, unspecified
0.693 0.307 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.692 0.308 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.692 0.308 0.000
Z65 Problems related to other psychosocial circumstances
0.691 0.309 0.000
Z64 Problems related to certain psychosocial circumstances
0.691 0.309 0.000
Z62 Other problems related to upbringing
0.691 0.309 0.000
Z61 Problems related to negative life events in childhood
0.691 0.309 0.000
Z58 Problems related to physical environment
0.691 0.309 0.000
Z56 Problems related to employment and unemployment
0.691 0.309 0.000
Z55 Problems related to education and literacy
0.691 0.309 0.000
I69.3 Sequelae of cerebral infarction
0.691 0.309 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.691 0.309 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.691 0.309 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.691 0.309 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.691 0.309 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.691 0.309 0.000
I60.8 Other subarachnoid haemorrhage
0.690 0.310 0.000
Z71.2 Person consulting for explanation of investigation findings
0.690 0.310 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.689 0.310 0.000
M05-M14 Inflammatory polyarthropathies
0.689 0.311 0.000
Z59.0 Homelessness
0.688 0.312 0.000
Z93.2 Ileostomy status
0.688 0.312 0.000
I49 Other cardiac arrhythmias
0.688 0.312 0.000
K75.9 Inflammatory liver disease, unspecified
0.687 0.313 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.686 0.314 0.000
M46.4 Discitis, unspecified
0.686 0.314 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.685 0.314 0.000
M17.0 Primary gonarthrosis, bilateral
0.685 0.315 0.000
I30 Acute pericarditis
0.684 0.316 0.000
Z90.3 Acquired absence of part of stomach
0.683 0.317 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.682 0.318 0.000
E40-E46 Malnutrition
0.682 0.318 0.000
S27 Injury of other and unspecified intrathoracic organs
0.682 0.318 0.000
Z22.3 Carrier of other specified bacterial diseases
0.682 0.318 0.000
Q60-Q64 Congenital malformations of the urinary system
0.681 0.319 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.681 0.319 0.000
S67 Crushing injury of wrist and hand
0.681 0.319 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.680 0.320 0.000
Z92.3 Personal history of irradiation
0.680 0.320 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.679 0.321 0.000
I72 Other aneurysm
0.679 0.321 0.000
I67.8 Other specified cerebrovascular diseases
0.678 0.322 0.000
M22.4 Chondromalacia patellae
0.678 0.322 0.000
I78 Diseases of capillaries
0.678 0.322 0.000
Z98 Other postsurgical states
0.677 0.323 0.000
C64-C68 Malignant neoplasms of urinary tract
0.676 0.324 0.000
M25.2 Flail joint
0.674 0.326 0.000
M25.1 Fistula of joint
0.674 0.326 0.000
Z93.0 Tracheostomy status
0.673 0.327 0.000
C77.1 Intrathoracic lymph nodes
0.673 0.327 0.000
K90 Intestinal malabsorption
0.673 0.327 0.000
Z90.5 Acquired absence of kidney
0.673 0.327 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.673 0.327 0.000
I85 Oesophageal varices
0.673 0.327 0.000
Y40 Systemic antibiotics
0.672 0.328 0.000
S62 Fracture at wrist and hand level
0.672 0.328 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.672 0.328 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.672 0.328 0.000
I67.5 Moyamoya disease
0.672 0.328 0.000
I67.4 Hypertensive encephalopathy
0.672 0.328 0.000
I67.3 Progressive vascular leukoencephalopathy
0.672 0.328 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.672 0.328 0.000
N48 Other disorders of penis
0.672 0.328 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.672 0.328 0.000
I34 Nonrheumatic mitral valve disorders
0.671 0.329 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.671 0.329 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.670 0.330 0.000
M31 Other necrotising vasculopathies
0.670 0.330 0.000
N18 Chronic renal failure
0.670 0.330 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.669 0.330 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.669 0.331 0.000
I73.8 Other specified peripheral vascular diseases
0.669 0.331 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.669 0.331 0.000
I77.5 Necrosis of artery
0.669 0.331 0.000
I77.4 Coeliac artery compression syndrome
0.669 0.331 0.000
I77.3 Arterial fibromuscular dysplasia
0.669 0.331 0.000
I77.2 Rupture of artery
0.669 0.331 0.000
S22.4 Multiple fractures of ribs
0.668 0.332 0.000
M16.1 Other primary coxarthrosis
0.668 0.332 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.668 0.332 0.000
D48.7 Other specified sites
0.668 0.332 0.000
D48.6 Breast
0.668 0.332 0.000
D48.4 Peritoneum
0.668 0.332 0.000
D48.3 Retroperitoneum
0.668 0.332 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.668 0.332 0.000
E85 Amyloidosis
0.668 0.332 0.000
E84 Cystic fibrosis
0.668 0.332 0.000
E79 Disorders of purine and pyrimidine metabolism
0.668 0.332 0.000
E77 Disorders of glycoprotein metabolism
0.668 0.332 0.000
E76 Disorders of glycosaminoglycan metabolism
0.668 0.332 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.668 0.332 0.000
E74 Other disorders of carbohydrate metabolism
0.668 0.332 0.000
E73 Lactose intolerance
0.668 0.332 0.000
E72 Other disorders of amino-acid metabolism
0.668 0.332 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.668 0.332 0.000
E70 Disorders of aromatic amino-acid metabolism
0.668 0.332 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.668 0.332 0.000
Chapter I Certain infectious and parasitic diseases
0.668 0.332 0.000
M40-M43 Deforming dorsopathies
0.668 0.332 0.000
Z92.9 Personal history of medical treatment, unspecified
0.667 0.332 0.000
Z92.5 Personal history of rehabilitation measures
0.667 0.332 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.667 0.333 0.000
M94 Other disorders of cartilage
0.667 0.333 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.666 0.334 0.000
I99 Other and unspecified disorders of circulatory system
0.666 0.334 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.665 0.335 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.665 0.335 0.000
C51 Malignant neoplasm of vulva
0.665 0.335 0.000
C58 Malignant neoplasm of placenta
0.665 0.335 0.000
C52 Malignant neoplasm of vagina
0.665 0.335 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.665 0.335 0.000
H02.8 Other specified disorders of eyelid
0.664 0.336 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.664 0.336 0.000
Q35-Q37 Cleft lip and cleft palate
0.664 0.336 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.664 0.336 0.000
Q00-Q07 Congenital malformations of the nervous system
0.664 0.336 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.664 0.336 0.000
Y98 Lifestyle-related condition
0.664 0.336 0.000
Y97 Environmental-pollution-related condition
0.664 0.336 0.000
Y96 Work-related condition
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.336 0.000
Y44 Agents primarily affecting blood constituents
0.664 0.336 0.000
M16.3 Other dysplastic coxarthrosis
0.662 0.337 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.662 0.338 0.000
Z60.2 Living alone
0.662 0.338 0.000
Z89.6 Acquired absence of leg above knee
0.662 0.338 0.000
Z99.1 Dependence on respirator
0.661 0.339 0.000
K42.1 Umbilical hernia with gangrene
0.661 0.339 0.000
C77.8 Lymph nodes of multiple regions
0.661 0.339 0.000
K46 Unspecified abdominal hernia
0.661 0.339 0.000
Z72.9 Problem related to lifestyle, unspecified
0.661 0.339 0.000
Z72.8 Other problems related to lifestyle
0.661 0.339 0.000
Z72.6 Gambling and betting
0.661 0.339 0.000
Z72.5 High-risk sexual behaviour
0.661 0.339 0.000
Z72.4 Inappropriate diet and eating habits
0.661 0.339 0.000
Z72.3 Lack of physical exercise
0.661 0.339 0.000
Z72.2 Drug use
0.661 0.339 0.000
M25.76 Osteophyte (Lower leg)
0.660 0.340 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.660 0.340 0.000
Z93.3 Colostomy status
0.660 0.340 0.000
Z74 Problems related to care-provider dependency
0.659 0.340 0.000
K77 Liver disorders in diseases classified elsewhere
0.659 0.341 0.000
K72 Hepatic failure, not elsewhere classified
0.659 0.341 0.000
K71 Toxic liver disease
0.659 0.341 0.000
H00 Hordeolum and chalazion
0.659 0.341 0.000
I95.1 Orthostatic hypotension
0.659 0.341 0.000
T78.2 Anaphylactic shock, unspecified
0.658 0.341 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.658 0.341 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.658 0.341 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.658 0.341 0.000
K43.4 Parastomal hernia with gangrene
0.658 0.341 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.658 0.341 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.658 0.341 0.000
K43.1 Ventral hernia with gangrene
0.658 0.341 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.658 0.342 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.657 0.343 0.000
K85.1 Biliary acute pancreatitis
0.657 0.343 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.657 0.343 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.657 0.343 0.000
S82 Fracture of lower leg, including ankle
0.657 0.343 0.000
H01 Other inflammation of eyelid
0.657 0.343 0.000
I42 Cardiomyopathy
0.656 0.344 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.655 0.345 0.000
K91.5 Postcholecystectomy syndrome
0.655 0.345 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.655 0.345 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.655 0.345 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.655 0.345 0.000
Chapter VI Diseases of the nervous system
0.655 0.345 0.000
Z89.5 Acquired absence of leg at or below knee
0.655 0.345 0.000
H04 Disorders of lachrymal system
0.653 0.347 0.000
Y57 Other and unspecified drugs and medicaments
0.652 0.348 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.652 0.348 0.000
M54 Dorsalgia
0.652 0.348 0.000
M17.3 Other posttraumatic gonarthrosis
0.652 0.348 0.000
I05-I09 Chronic rheumatic heart diseases
0.651 0.349 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.650 0.349 0.000
Z73.3 Stress, not elsewhere classified
0.650 0.350 0.000
S65 Injury of blood vessels at wrist and hand level
0.650 0.350 0.000
S69 Other and unspecified injuries of wrist and hand
0.650 0.350 0.000
K86.3 Pseudocyst of pancreas
0.649 0.351 0.000
C73 Malignant neoplasm of thyroid gland
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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