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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78424619
log Bayes Factor = 12.1013
Chromosome 4   position 128,704,037  (GRCh37) Explore rs78424619 on Ensembl!
Variant rs78424619 is part of Cluster X0032

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
A00-A09 Intestinal infectious diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.999 0.001 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.998 0.002 0.000
K70-K77 Diseases of liver
0.998 0.002 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.996 0.004 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.996 0.004 0.000
M50-M54 Other dorsopathies
0.993 0.007 0.000
A30-A49 Other bacterial diseases
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
Chapter VIII Diseases of the ear and mastoid process
0.984 0.016 0.000
A41 Other septicaemia
0.982 0.018 0.000
M50 Cervical disk disorders
0.982 0.018 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
K70 Alcoholic liver disease
0.976 0.024 0.000
F10.1 Harmful use
0.970 0.030 0.000
T81 Complications of procedures, not elsewhere classified
0.970 0.030 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.968 0.032 0.000
K90-K93 Other diseases of the digestive system
0.965 0.035 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.964 0.036 0.000
A41.9 Septicaemia, unspecified
0.959 0.041 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.958 0.042 0.000
M50.1 Cervical disk disorder with radiculopathy
0.954 0.046 0.000
K02 Dental caries
0.951 0.049 0.000
K76 Other diseases of liver
0.950 0.050 0.000
H90-H95 Other disorders of ear
0.940 0.060 0.000
M15-M19 Arthrosis
0.939 0.061 0.000
F10.3 Withdrawal state
0.930 0.070 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.928 0.072 0.000
K72 Hepatic failure, not elsewhere classified
0.925 0.075 0.000
G40-G47 Episodic and paroxysmal disorders
0.921 0.079 0.000
K02.9 Dental caries, unspecified
0.919 0.081 0.000
K92 Other diseases of digestive system
0.917 0.083 0.000
F10.2 Dependence syndrome
0.914 0.086 0.000
M19 Other arthrosis
0.906 0.094 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.903 0.097 0.000
G40 Epilepsy
0.899 0.101 0.000
M70-M79 Other soft tissue disorders
0.898 0.102 0.000
G40.9 Epilepsy, unspecified
0.889 0.111 0.000
F10.0 Acute intoxication
0.887 0.113 0.000
K70.9 Alcoholic liver disease, unspecified
0.887 0.113 0.000
H65-H75 Diseases of middle ear and mastoid
0.886 0.114 0.000
K04 Diseases of pulp and periapical tissues
0.885 0.115 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.884 0.115 0.000
K13 Other diseases of lip and oral mucosa
0.884 0.116 0.000
M72 Fibroblastic disorders
0.872 0.128 0.000
S20-S29 Injuries to the thorax
0.871 0.129 0.000
K01 Embedded and impacted teeth
0.869 0.131 0.000
G90-G99 Other disorders of the nervous system
0.868 0.132 0.000
M54 Dorsalgia
0.866 0.134 0.000
H90 Conductive and sensorineural hearing loss
0.858 0.142 0.000
O47 False labour
0.858 0.142 0.000
T86 Failure and rejection of transplanted organs and tissues
0.857 0.143 0.000
K50-K52 Noninfective enteritis and colitis
0.856 0.144 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.854 0.146 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.853 0.147 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.852 0.148 0.000
K76.6 Portal hypertension
0.851 0.149 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.851 0.149 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.850 0.150 0.000
M19.9 Arthrosis, unspecified
0.848 0.152 0.000
S00-S09 Injuries to the head
0.847 0.153 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
T66-T78 Other and unspecified effects of external causes
0.842 0.158 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.841 0.159 0.000
H91 Other hearing loss
0.841 0.159 0.000
S90-S99 Injuries to the ankle and foot
0.840 0.160 0.000
Y52 Agents primarily affecting the cardiovascular system
0.835 0.165 0.000
K09 Cysts of oral region, not elsewhere classified
0.834 0.166 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.831 0.169 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.830 0.170 0.000
K70.3 Alcoholic cirrhosis of liver
0.829 0.171 0.000
K70.1 Alcoholic hepatitis
0.827 0.173 0.000
K72.9 Hepatic failure, unspecified
0.826 0.174 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.821 0.179 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.821 0.179 0.000
A08 Viral and other specified intestinal infections
0.820 0.180 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.820 0.180 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.819 0.181 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.818 0.182 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.818 0.182 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.813 0.187 0.000
O00-O08 Pregnancy with abortive outcome
0.811 0.189 0.000
M18 Arthrosis of first carpometacarpal joint
0.811 0.189 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.811 0.189 0.000
M19.0 Primary arthrosis of other joints
0.811 0.189 0.000
Y57 Other and unspecified drugs and medicaments
0.810 0.190 0.000
H72 Perforation of tympanic membrane
0.808 0.192 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.807 0.193 0.000
M50.0 Cervical disk disorder with myelopathy
0.807 0.193 0.000
K70.4 Alcoholic hepatic failure
0.806 0.194 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.805 0.195 0.000
M50.3 Other cervical disk degeneration
0.804 0.196 0.000
G20-G26 Extrapyramidal and movement disorders
0.803 0.197 0.000
M20-M25 Other joint disorders
0.802 0.198 0.000
K12 Stomatitis and related lesions
0.801 0.199 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.799 0.201 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.797 0.203 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.793 0.207 0.000
K50 Crohn's disease [regional enteritis]
0.793 0.207 0.000
M50.2 Other cervical disk displacement
0.788 0.212 0.000
K72.0 Acute and subacute hepatic failure
0.788 0.212 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.786 0.214 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.785 0.215 0.000
K04.8 Radicular cyst
0.785 0.215 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.782 0.218 0.000
K00 Disorders of tooth development and eruption
0.780 0.220 0.000
K01.1 Impacted teeth
0.778 0.222 0.000
H80-H83 Diseases of inner ear
0.777 0.223 0.000
O41 Other disorders of amniotic fluid and membranes
0.777 0.223 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.776 0.224 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.775 0.225 0.000
F10.4 Withdrawal state with delirium
0.775 0.225 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.774 0.226 0.000
M40-M43 Deforming dorsopathies
0.770 0.230 0.000
F99-F99 Unspecified mental disorder
0.770 0.230 0.000
H91.9 Hearing loss, unspecified
0.770 0.230 0.000
G70-G73 Diseases of myoneural junction and muscle
0.765 0.235 0.000
B25-B34 Other viral diseases
0.764 0.236 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.762 0.238 0.000
V40-V49 Car occupant injured in transport accident
0.760 0.239 0.000
S70-S79 Injuries to the hip and thigh
0.760 0.240 0.000
S10-S19 Injuries to the neck
0.760 0.240 0.000
W50-W64 Exposure to animate mechanical forces
0.759 0.241 0.000
M51 Other intervertebral disk disorders
0.758 0.242 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.753 0.247 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.752 0.248 0.000
M45-M49 Spondylopathies
0.750 0.249 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.748 0.252 0.000
H90.2 Conductive hearing loss, unspecified
0.748 0.252 0.000
O40 Polyhydramnios
0.748 0.252 0.000
Y44 Agents primarily affecting blood constituents
0.748 0.252 0.000
G30-G32 Other degenerative diseases of the nervous system
0.747 0.253 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.747 0.253 0.000
M25 Other joint disorders, not elsewhere classified
0.745 0.255 0.000
M54.9 Dorsalgia, unspecified
0.744 0.256 0.000
M86-M90 Other osteopathies
0.742 0.258 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.741 0.259 0.000
E20-E35 Disorders of other endocrine glands
0.738 0.262 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.738 0.262 0.000
A41.8 Other specified septicaemia
0.738 0.262 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.738 0.262 0.000
G44 Other headache syndromes
0.737 0.263 0.000
K07 Dentofacial anomalies [including malocclusion]
0.736 0.264 0.000
G62 Other polyneuropathies
0.734 0.266 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.731 0.269 0.000
K75 Other inflammatory liver diseases
0.730 0.270 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.730 0.270 0.000
W20-W49 Exposure to inanimate mechanical forces
0.730 0.270 0.000
T78 Adverse effects, not elsewhere classified
0.729 0.271 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.728 0.271 0.000
T81.9 Unspecified complication of procedure
0.728 0.272 0.000
Y45.0 Opioids and related analgesics
0.728 0.272 0.000
M65-M68 Disorders of synovium and tendon
0.727 0.273 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.726 0.274 0.000
W00-W19 Falls
0.726 0.274 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.725 0.275 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.723 0.277 0.000
T79-T79 Certain early complications of trauma
0.722 0.278 0.000
S02 Fracture of skull and facial bones
0.722 0.278 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.722 0.278 0.000
B15-B19 Viral hepatitis
0.721 0.279 0.000
K09.0 Developmental odontogenic cysts
0.718 0.282 0.000
K50.1 Crohn's disease of large intestine
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
Y43 Primarily systemic agents
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
H60-H62 Diseases of external ear
0.717 0.283 0.000
A07 Other protozoal intestinal diseases
0.716 0.284 0.000
A06 Amoebiasis
0.716 0.284 0.000
A05 Other bacterial foodborne intoxications
0.716 0.284 0.000
A03 Shigellosis
0.716 0.284 0.000
A02 Other Salmonella infections
0.716 0.284 0.000
A01 Typhoid and paratyphoid fevers
0.716 0.284 0.000
A00 Cholera
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.716 0.284 0.000
K10 Other diseases of jaws
0.716 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.715 0.284 0.000
K73 Chronic hepatitis, not elsewhere classified
0.715 0.284 0.000
K71 Toxic liver disease
0.715 0.284 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
F11 Mental and behavioural disorders due to use of opioids
0.715 0.285 0.000
F10.9 Unspecified mental and behavioural disorder
0.714 0.286 0.000
F10.8 Other mental and behavioural disorders
0.714 0.286 0.000
F10.7 Residual and late-onset psychotic disorder
0.714 0.286 0.000
F10.6 Amnesic syndrome
0.714 0.286 0.000
F10.5 Psychotic disorder
0.714 0.286 0.000
K03 Other diseases of hard tissues of teeth
0.714 0.286 0.000
Chapter XXII Codes for special purposes
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
K76.9 Liver disease, unspecified
0.713 0.287 0.000
Y54.3 Benzothiadiazine derivatives
0.712 0.288 0.000
K04.5 Chronic apical periodontitis
0.710 0.290 0.000
Y40 Systemic antibiotics
0.710 0.290 0.000
A48 Other bacterial diseases, not elsewhere classified
0.709 0.291 0.000
A44 Bartonellosis
0.709 0.291 0.000
A43 Nocardiosis
0.709 0.291 0.000
A42 Actinomycosis
0.709 0.291 0.000
A40 Streptococcal septicaemia
0.709 0.291 0.000
A39 Meningococcal infection
0.709 0.291 0.000
A37 Whooping cough
0.709 0.291 0.000
A36 Diphtheria
0.709 0.291 0.000
A32 Listeriosis
0.709 0.291 0.000
A31 Infection due to other mycobacteria
0.709 0.291 0.000
A30 Leprosy [Hansen's disease]
0.709 0.291 0.000
A46 Erysipelas
0.709 0.291 0.000
A38 Scarlet fever
0.709 0.291 0.000
A35 Other tetanus
0.709 0.291 0.000
A34 Obstetrical tetanus
0.709 0.291 0.000
A33 Tetanus neonatorum
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.709 0.291 0.000
A80-A89 Viral infections of the central nervous system
0.709 0.291 0.000
Y54.5 Other diuretics
0.709 0.291 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.707 0.293 0.000
M16 Coxarthrosis [arthrosis of hip]
0.707 0.293 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
O32.8 Maternal care for other malpresentation of foetus
0.707 0.293 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.706 0.294 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.705 0.294 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.705 0.295 0.000
A41.4 Septicaemia due to anaerobes
0.704 0.296 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.704 0.296 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.704 0.296 0.000
M50.9 Cervical disk disorder, unspecified
0.704 0.296 0.000
M50.8 Other cervical disk disorders
0.704 0.296 0.000
M19.94 Arthrosis, unspecified (Hand)
0.702 0.298 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.702 0.298 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
X50-X57 Overexertion, travel and privation
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V80-V89 Other land transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V20-V29 Motorcycle rider injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.700 0.300 0.000
K70.0 Alcoholic fatty liver
0.700 0.300 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.700 0.300 0.000
S50-S59 Injuries to the elbow and forearm
0.698 0.302 0.000
Q60-Q64 Congenital malformations of the urinary system
0.698 0.302 0.000
S01 Open wound of head
0.698 0.302 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.698 0.302 0.000
K13.0 Diseases of lips
0.698 0.302 0.000
Y57.9 Drug or medicament, unspecified
0.696 0.303 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.696 0.304 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.696 0.304 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.696 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.694 0.306 0.000
Y58 Bacterial vaccines
0.694 0.306 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.694 0.306 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.694 0.306 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.694 0.306 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.694 0.306 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.694 0.306 0.000
Y48 Anaesthetics and therapeutic gases
0.694 0.306 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.694 0.306 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.694 0.306 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.694 0.306 0.000
A08.4 Viral intestinal infection, unspecified
0.692 0.308 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.692 0.308 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.692 0.308 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.691 0.309 0.000
T31 Burns classified according to extent of body surface involved
0.690 0.309 0.000
O36 Maternal care for other known or suspected foetal problems
0.689 0.311 0.000
O85-O92 Complications predominantly related to the puerperium
0.687 0.313 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.687 0.313 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.687 0.313 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.686 0.314 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.686 0.314 0.000
H92 Otalgia and effusion of ear
0.685 0.315 0.000
K51 Ulcerative colitis
0.685 0.315 0.000
S91 Open wound of ankle and foot
0.684 0.315 0.000
M05-M14 Inflammatory polyarthropathies
0.682 0.318 0.000
S20 Superficial injury of thorax
0.682 0.318 0.000
K02.8 Other dental caries
0.682 0.318 0.000
K02.5 Caries with pulp exposure
0.682 0.318 0.000
K02.4 Odontoclasia
0.682 0.318 0.000
K02.3 Arrested dental caries
0.682 0.318 0.000
K02.2 Caries of cementum
0.682 0.318 0.000
K02.1 Caries of dentin
0.682 0.318 0.000
K02.0 Caries limited to enamel
0.682 0.318 0.000
K05 Gingivitis and periodontal diseases
0.682 0.318 0.000
K76.7 Hepatorenal syndrome
0.681 0.319 0.000
K76.5 Hepatic veno-occlusive disease
0.681 0.319 0.000
K76.4 Peliosis hepatis
0.681 0.319 0.000
K76.3 Infarction of liver
0.681 0.319 0.000
K76.2 Central haemorrhagic necrosis of liver
0.681 0.319 0.000
K76.1 Chronic passive congestion of liver
0.681 0.319 0.000
M54.5 Low back pain
0.681 0.319 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.680 0.320 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.679 0.321 0.000
K14 Diseases of tongue
0.679 0.321 0.000
X60-X84 Intentional self-harm
0.678 0.322 0.000
S09 Other and unspecified injuries of head
0.678 0.322 0.000
F45 Somatoform disorders
0.678 0.322 0.000
K91.4 Colostomy and enterostomy malfunction
0.678 0.322 0.000
K11 Diseases of salivary glands
0.677 0.323 0.000
H65 Nonsuppurative otitis media
0.676 0.324 0.000
G25 Other extrapyramidal and movement disorders
0.676 0.324 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.676 0.324 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.675 0.325 0.000
K50.8 Other Crohn's disease
0.674 0.326 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.674 0.326 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.674 0.326 0.000
T86.0 Bone-marrow transplant rejection
0.674 0.326 0.000
M15 Polyarthrosis
0.673 0.327 0.000
A49 Bacterial infection of unspecified site
0.672 0.327 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.672 0.328 0.000
H83 Other diseases of inner ear
0.671 0.329 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.671 0.329 0.000
M77 Other enthesopathies
0.669 0.331 0.000
H66 Suppurative and unspecified otitis media
0.668 0.332 0.000
O45 Premature separation of placenta [abruptio placentae]
0.666 0.334 0.000
O44 Placenta praevia
0.666 0.334 0.000
O43 Placental disorders
0.666 0.334 0.000
O33 Maternal care for known or suspected disproportion
0.666 0.334 0.000
O31 Complications specific to multiple gestation
0.666 0.334 0.000
Y88 Sequelae of surgical and medical care as external cause
0.665 0.335 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.664 0.335 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.664 0.336 0.000
K72.1 Chronic hepatic failure
0.663 0.336 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.663 0.336 0.000
G58 Other mononeuropathies
0.662 0.338 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.339 0.000
H90.5 Sensorineural hearing loss, unspecified
0.661 0.339 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.661 0.339 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.660 0.340 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.660 0.340 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.660 0.340 0.000
G41 Status epilepticus
0.660 0.340 0.000
O32.2 Maternal care for transverse and oblique lie
0.660 0.340 0.000
K76.8 Other specified diseases of liver
0.659 0.341 0.000
M80-M85 Disorders of bone density and structure
0.658 0.342 0.000
K92.9 Disease of digestive system, unspecified
0.657 0.342 0.000
K92.8 Other specified diseases of digestive system
0.657 0.342 0.000
E27 Other disorders of adrenal gland
0.656 0.344 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.656 0.344 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.655 0.344 0.000
F43 Reaction to severe stress, and adjustment disorders
0.655 0.345 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.654 0.345 0.000
D80-D89 Certain disorders involving the immune mechanism
0.654 0.346 0.000
F22 Persistent delusional disorders
0.653 0.347 0.000
T82.3 Mechanical complication of other vascular grafts
0.652 0.348 0.000
Q80-Q89 Other congenital malformations
0.652 0.348 0.000
H93 Other disorders of ear, not elsewhere classified
0.650 0.350 0.000
M34 Systemic sclerosis
0.650 0.350 0.000
M19.8 Other specified arthrosis
0.650 0.350 0.000
M19.2 Other secondary arthrosis
0.650 0.350 0.000
M41 Scoliosis
0.649 0.351 0.000
O00 Ectopic pregnancy
0.649 0.351 0.000
G62.9 Polyneuropathy, unspecified
0.649 0.351 0.000
Y86 Sequelae of other accidents
0.646 0.354 0.000
O80-O84 Delivery
0.646 0.354 0.000
G40.8 Other epilepsy
0.645 0.355 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.645 0.355 0.000
G40.5 Special epileptic syndromes
0.645 0.355 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.645 0.355 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.645 0.355 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.645 0.355 0.000
O02 Other abnormal products of conception
0.645 0.355 0.000
F29 Unspecified nonorganic psychosis
0.644 0.356 0.000
M76 Enthesopathies of lower limb, excluding foot
0.643 0.356 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.643 0.356 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.643 0.357 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.642 0.357 0.000
M25.7 Osteophyte
0.642 0.357 0.000
D70 Agranulocytosis
0.642 0.358 0.000
M54.4 Lumbago with sciatica
0.641 0.359 0.000
V10-V19 Pedal cyclist injured in transport accident
0.640 0.360 0.000
S29 Other and unspecified injuries of thorax
0.639 0.361 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.639 0.361 0.000
H73 Other disorders of tympanic membrane
0.638 0.361 0.000
Y45.2 Propionic acid derivatives
0.638 0.362 0.000
G96 Other disorders of central nervous system
0.637 0.363 0.000
K35-K38 Diseases of appendix
0.637 0.363 0.000
O48 Prolonged pregnancy
0.636 0.364 0.000
G50 Disorders of trigeminal nerve
0.636 0.364 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.635 0.365 0.000
H74 Other disorders of middle ear and mastoid
0.635 0.365 0.000
H70 Mastoiditis and related conditions
0.635 0.365 0.000
H69 Other disorders of Eustachian tube
0.635 0.365 0.000
H68 Eustachian salpingitis and obstruction
0.635 0.365 0.000
H67 Otitis media in diseases classified elsewhere
0.635 0.365 0.000
G91 Hydrocephalus
0.635 0.365 0.000
K04.6 Periapical abscess with sinus
0.635 0.365 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.635 0.365 0.000
K04.3 Abnormal hard tissue formation in pulp
0.635 0.365 0.000
K04.2 Pulp degeneration
0.635 0.365 0.000
K04.1 Necrosis of pulp
0.635 0.365 0.000
K04.0 Pulpitis
0.635 0.365 0.000
M16.1 Other primary coxarthrosis
0.634 0.366 0.000
F12.1 Harmful use
0.634 0.366 0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
0.633 0.366 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.633 0.366 0.000
K13.5 Oral submucous fibrosis
0.633 0.366 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.633 0.366 0.000
K13.3 Hairy leukoplakia
0.633 0.366 0.000
K13.1 Cheek and lip biting
0.633 0.366 0.000
K90 Intestinal malabsorption
0.633 0.367 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.633 0.367 0.000
M71 Other bursopathies
0.633 0.367 0.000
K12.1 Other forms of stomatitis
0.633 0.367 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.633 0.367 0.000
K91.3 Postoperative intestinal obstruction
0.632 0.368 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.631 0.369 0.000
G43 Migraine
0.631 0.369 0.000
G54 Nerve root and plexus disorders
0.631 0.369 0.000
M21 Other acquired deformities of limbs
0.629 0.371 0.000
B35-B49 Mycoses
0.629 0.371 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.628 0.372 0.000
M54.2 Cervicalgia
0.627 0.373 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.627 0.373 0.000
S27 Injury of other and unspecified intrathoracic organs
0.627 0.373 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.626 0.374 0.000
T82.1 Mechanical complication of cardiac electronic device
0.626 0.374 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.626 0.374 0.000
K00.6 Disturbances in tooth eruption
0.625 0.374 0.000
M72.9 Fibroblastic disorder, unspecified
0.625 0.375 0.000
M72.8 Other fibroblastic disorders
0.625 0.375 0.000
M72.6 Necrotizing fasciitis
0.625 0.375 0.000
M72.5 Fasciitis, not elsewhere classified
0.625 0.375 0.000
M72.4 Pseudosarcomatous fibromatosis
0.625 0.375 0.000
M72.3 Nodular fasciitis
0.625 0.375 0.000
M72.2 Plantar fascial fibromatosis
0.625 0.375 0.000
M72.1 Knuckle pads
0.625 0.375 0.000
M19.1 Posttraumatic arthrosis of other joints
0.625 0.375 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.624 0.376 0.000
S26 Injury of heart
0.624 0.376 0.000
S25 Injury of blood vessels of thorax
0.624 0.376 0.000
S24 Injury of nerves and spinal cord at thorax level
0.624 0.376 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.624 0.376 0.000
S21 Open wound of thorax
0.624 0.376 0.000
K01.0 Embedded teeth
0.623 0.377 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.622 0.378 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.622 0.378 0.000
G90 Disorders of autonomic nervous system
0.622 0.378 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.622 0.378 0.000
G92 Toxic encephalopathy
0.622 0.378 0.000
O30 Multiple gestation
0.622 0.378 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.622 0.378 0.000
E50-E64 Other nutritional deficiencies
0.621 0.379 0.000
A04 Other bacterial intestinal infections
0.621 0.379 0.000
M54.8 Other dorsalgia
0.621 0.379 0.000
M54.6 Pain in thoracic spine
0.621 0.379 0.000
M54.0 Panniculitis affecting regions of neck and back
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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