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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78516619
log Bayes Factor = 61.5791
Chromosome 1   position 168,889,373  (GRCh37) Explore rs78516619 on Ensembl!
Variant rs78516619 is part of Cluster X0110

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D68.2 Hereditary deficiency of other clotting factors
1.000 0.000 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
1.000 0.000 0.000
Z86.7 Personal history of diseases of the circulatory system
1.000 0.000 0.000
D68 Other coagulation defects
1.000 0.000 0.000
I80 Phlebitis and thrombophlebitis
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
1.000 0.000 0.000
Z92 Personal history of medical treatment
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
I26 Pulmonary embolism
1.000 0.000 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
M79.8 Other specified soft tissue disorders
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Z86 Personal history of certain other diseases
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.995 0.005 0.000
D17 Benign lipomatous neoplasm
0.994 0.006 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.989 0.011 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.987 0.013 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.985 0.015 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.985 0.015 0.000
Chapter XIV Diseases of the genitourinary system
0.978 0.022 0.000
R07 Pain in throat and chest
0.977 0.023 0.000
Z53.9 Procedure not carried out, unspecified reason
0.974 0.026 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.974 0.026 0.000
M50-M54 Other dorsopathies
0.974 0.026 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.972 0.028 0.000
R79 Other abnormal findings of blood chemistry
0.965 0.035 0.000
Chapter VII Diseases of the eye and adnexa
0.962 0.038 0.000
Z50 Care involving use of rehabilitation procedures
0.956 0.044 0.000
D68.5 Primary Thrombophilia
0.955 0.045 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.951 0.049 0.000
D25 Leiomyoma of uterus
0.949 0.051 0.000
R26 Abnormalities of gait and mobility
0.946 0.054 0.000
Chapter I Certain infectious and parasitic diseases
0.945 0.055 0.000
D68.8 Other specified coagulation defects
0.943 0.057 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.941 0.059 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.939 0.061 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.938 0.062 0.000
N30-N39 Other diseases of urinary system
0.936 0.064 0.000
H40-H42 Glaucoma
0.934 0.066 0.000
Z50.1 Other physical therapy
0.931 0.069 0.000
M51 Other intervertebral disk disorders
0.928 0.072 0.000
Chapter V Mental and behavioural disorders
0.925 0.075 0.000
O60-O75 Complications of labour and delivery
0.923 0.077 0.000
C15-C26 Malignant neoplasms of digestive organs
0.920 0.080 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.920 0.080 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.916 0.084 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.914 0.086 0.000
H40 Glaucoma
0.914 0.086 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.913 0.087 0.000
R00 Abnormalities of heart beat
0.913 0.087 0.000
R07.3 Other chest pain
0.911 0.089 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.900 0.100 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.898 0.102 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.897 0.103 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.895 0.105 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.894 0.106 0.000
Z45 Adjustment and management of implanted device
0.892 0.108 0.000
H40.1 Primary open-angle glaucoma
0.886 0.114 0.000
N39 Other disorders of urinary system
0.885 0.115 0.000
I82 Other venous embolism and thrombosis
0.885 0.115 0.000
N20-N23 Urolithiasis
0.884 0.116 0.000
N97 Female infertility
0.883 0.117 0.000
Chapter X Diseases of the respiratory system
0.881 0.119 0.000
Chapter VI Diseases of the nervous system
0.880 0.120 0.000
N83.2 Other and unspecified ovarian cysts
0.880 0.120 0.000
M51.2 Other specified intervertebral disk displacement
0.876 0.124 0.000
D36 Benign neoplasm of other and unspecified sites
0.873 0.127 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.872 0.128 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.870 0.130 0.000
M54 Dorsalgia
0.870 0.130 0.000
M45-M49 Spondylopathies
0.870 0.130 0.000
Z51 Other medical care
0.869 0.131 0.000
D25.9 Leiomyoma of uterus, unspecified
0.867 0.133 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.861 0.139 0.000
D23 Other benign neoplasms of skin
0.855 0.145 0.000
Z92.3 Personal history of irradiation
0.854 0.146 0.000
M79.6 Pain in limb
0.851 0.149 0.000
Z88.6 Personal history of allergy to analgesic agent
0.851 0.149 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.846 0.154 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.844 0.156 0.000
N97.9 Female infertility, unspecified
0.843 0.157 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.841 0.159 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.841 0.159 0.000
H53-H54 Visual disturbances and blindness
0.840 0.160 0.000
R07.4 Chest pain, unspecified
0.838 0.162 0.000
O36 Maternal care for other known or suspected foetal problems
0.835 0.165 0.000
D80-D89 Certain disorders involving the immune mechanism
0.834 0.166 0.000
I60-I69 Cerebrovascular diseases
0.833 0.167 0.000
I87 Other disorders of veins
0.831 0.169 0.000
N32 Other disorders of bladder
0.831 0.169 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.830 0.170 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.830 0.170 0.000
M65-M68 Disorders of synovium and tendon
0.830 0.170 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.830 0.170 0.000
R00.1 Bradycardia, unspecified
0.829 0.171 0.000
R27 Other lack of coordination
0.827 0.173 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.826 0.174 0.000
Chapter VIII Diseases of the ear and mastoid process
0.825 0.175 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.825 0.175 0.000
D24 Benign neoplasm of breast
0.822 0.178 0.000
Z94 Transplanted organ and tissue status
0.818 0.182 0.000
R07.1 Chest pain on breathing
0.817 0.183 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.816 0.184 0.000
Z88.2 Personal history of allergy to sulphonamides
0.814 0.186 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.814 0.186 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.812 0.188 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.811 0.189 0.000
M05-M14 Inflammatory polyarthropathies
0.811 0.189 0.000
Z51.1 Chemotherapy session for neoplasm
0.811 0.189 0.000
Z37 Outcome of delivery
0.810 0.190 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.810 0.190 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.810 0.190 0.000
D68.0 Von Willebrand's disease
0.810 0.190 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.810 0.190 0.000
M79.1 Myalgia
0.808 0.192 0.000
Z92.0 Personal history of contraception
0.808 0.192 0.000
M79.7 Fibromyalgia
0.805 0.195 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.803 0.197 0.000
I82.8 Embolism and thrombosis of other specified veins
0.802 0.198 0.000
O80-O84 Delivery
0.802 0.198 0.000
H40.9 Glaucoma, unspecified
0.802 0.198 0.000
S40-S49 Injuries to the shoulder and upper arm
0.800 0.200 0.000
Z45.2 Adjustment and management of vascular access device
0.798 0.202 0.000
D10 Benign neoplasm of mouth and pharynx
0.798 0.202 0.000
N39.0 Urinary tract infection, site not specified
0.797 0.203 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.795 0.205 0.000
C18 Malignant neoplasm of colon
0.794 0.206 0.000
Chapter XX External causes of morbidity and mortality
0.794 0.206 0.000
S20-S29 Injuries to the thorax
0.793 0.207 0.000
O47 False labour
0.792 0.208 0.000
Z93 Artificial opening status
0.792 0.208 0.000
Z54 Convalescence
0.792 0.208 0.000
Z53.0 Procedure not carried out because of contraindication
0.791 0.209 0.000
M71 Other bursopathies
0.790 0.210 0.000
D45 Polycythaemia vera
0.790 0.210 0.000
D27 Benign neoplasm of ovary
0.790 0.210 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.789 0.211 0.000
J95-J99 Other diseases of the respiratory system
0.788 0.212 0.000
R26.0 Ataxic gait
0.788 0.212 0.000
I05-I09 Chronic rheumatic heart diseases
0.788 0.212 0.000
N20 Calculus of kidney and ureter
0.786 0.214 0.000
R01 Cardiac murmurs and other cardiac sounds
0.786 0.214 0.000
Z35 Supervision of high-risk pregnancy
0.783 0.217 0.000
B95-B98 Bacterial, viral and other infectious agents
0.782 0.218 0.000
D23.5 Skin of trunk
0.781 0.219 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.781 0.219 0.000
R06 Abnormalities of breathing
0.780 0.220 0.000
M47 Spondylosis
0.779 0.221 0.000
Z47 Other orthopaedic follow-up care
0.779 0.221 0.000
D25.2 Subserosal leiomyoma of uterus
0.778 0.222 0.000
M77 Other enthesopathies
0.777 0.223 0.000
G90-G99 Other disorders of the nervous system
0.777 0.223 0.000
Z86.0 Personal history of other neoplasms
0.775 0.225 0.000
Chapter XXII Codes for special purposes
0.774 0.226 0.000
N83.1 Corpus luteum cyst
0.773 0.227 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.771 0.229 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.771 0.229 0.000
I85 Oesophageal varices
0.770 0.230 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.769 0.231 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.769 0.231 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.769 0.231 0.000
A30-A49 Other bacterial diseases
0.767 0.233 0.000
B07 Viral warts
0.766 0.234 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.766 0.234 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.766 0.234 0.000
R42 Dizziness and giddiness
0.766 0.234 0.000
N32.3 Diverticulum of bladder
0.764 0.236 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.763 0.237 0.000
Z88.5 Personal history of allergy to narcotic agent
0.762 0.238 0.000
M40-M43 Deforming dorsopathies
0.761 0.239 0.000
R73 Elevated blood glucose level
0.760 0.239 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.760 0.240 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.760 0.240 0.000
O00-O08 Pregnancy with abortive outcome
0.759 0.241 0.000
D68.9 Coagulation defect, unspecified
0.759 0.241 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.756 0.244 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.755 0.245 0.000
D00-D09 In situ neoplasms
0.755 0.245 0.000
N80 Endometriosis
0.755 0.245 0.000
R07.2 Precordial pain
0.754 0.246 0.000
D25.0 Submucous leiomyoma of uterus
0.752 0.248 0.000
Z46 Fitting and adjustment of other devices
0.752 0.248 0.000
M20-M25 Other joint disorders
0.752 0.248 0.000
M54.3 Sciatica
0.750 0.250 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.749 0.251 0.000
N89 Other noninflammatory disorders of vagina
0.749 0.251 0.000
N87 Dysplasia of cervix uteri
0.749 0.251 0.000
H40.0 Glaucoma suspect
0.747 0.253 0.000
C25 Malignant neoplasm of pancreas
0.746 0.254 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.745 0.255 0.000
Z51.0 Radiotherapy session
0.745 0.255 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.744 0.256 0.000
M47.9 Spondylosis, unspecified
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
O36.8 Maternal care for other specified foetal problems
0.742 0.258 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.742 0.258 0.000
I83 Varicose veins of lower extremities
0.741 0.259 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.741 0.259 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.741 0.259 0.000
R07.0 Pain in throat
0.740 0.260 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.740 0.260 0.000
D69 Purpura and other haemorrhagic conditions
0.739 0.261 0.000
Z97 Presence of other devices
0.737 0.263 0.000
C20 Malignant neoplasm of rectum
0.737 0.263 0.000
Z37.0 Single live birth
0.736 0.264 0.000
B35-B49 Mycoses
0.736 0.264 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.735 0.265 0.000
Z52 Donors of organs and tissues
0.735 0.265 0.000
I67 Other cerebrovascular diseases
0.734 0.266 0.000
Z83 Family history of other specific disorders
0.734 0.266 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.734 0.266 0.000
O30 Multiple gestation
0.733 0.267 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.732 0.268 0.000
N30 Cystitis
0.731 0.269 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.730 0.270 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.729 0.271 0.000
O41 Other disorders of amniotic fluid and membranes
0.728 0.272 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.727 0.272 0.000
R00.0 Tachycardia, unspecified
0.727 0.273 0.000
O66 Other obstructed labour
0.727 0.273 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.727 0.273 0.000
H65-H75 Diseases of middle ear and mastoid
0.727 0.273 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.725 0.275 0.000
N94.1 Dyspareunia
0.725 0.275 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.724 0.276 0.000
Z51.8 Other specified medical care
0.724 0.276 0.000
Z29 Need for other prophylactic measures
0.724 0.276 0.000
J98 Other respiratory disorders
0.723 0.277 0.000
F41 Other anxiety disorders
0.723 0.277 0.000
R27.0 Ataxia, unspecified
0.722 0.277 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.721 0.279 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.718 0.282 0.000
H53 Visual disturbances
0.717 0.282 0.000
D68.6 Other Thrombophilia
0.717 0.283 0.000
D68.4 Acquired coagulation factor deficiency
0.717 0.283 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.717 0.283 0.000
D68.1 Hereditary factor XI deficiency
0.717 0.283 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.717 0.283 0.000
Z92.8 Personal history of other medical treatment
0.717 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.717 0.283 0.000
I88 Nonspecific lymphadenitis
0.717 0.283 0.000
I86 Varicose veins of other sites
0.717 0.283 0.000
I81 Portal vein thrombosis
0.717 0.283 0.000
D55-D59 Haemolytic anaemias
0.717 0.283 0.000
D67 Hereditary factor IX deficiency
0.717 0.283 0.000
D66 Hereditary factor VIII deficiency
0.717 0.283 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.717 0.283 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.717 0.283 0.000
I28 Other diseases of pulmonary vessels
0.717 0.283 0.000
N39.9 Disorder of urinary system, unspecified
0.717 0.283 0.000
M79.9 Soft tissue disorder, unspecified
0.717 0.283 0.000
M79.5 Residual foreign body in soft tissue
0.717 0.283 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.717 0.283 0.000
M79.3 Panniculitis, unspecified
0.717 0.283 0.000
M79.2 Neuralgia and neuritis, unspecified
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
M79.88 Other specified soft tissue disorders (Other)
0.717 0.283 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.717 0.283 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.717 0.283 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.717 0.283 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.717 0.283 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.717 0.283 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.717 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.717 0.283 0.000
D32 Benign neoplasm of meninges
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
Z49 Care involving dialysis
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
O63 Long labour
0.716 0.284 0.000
N95 Menopausal and other perimenopausal disorders
0.716 0.284 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.716 0.284 0.000
D31 Benign neoplasm of eye and adnexa
0.716 0.284 0.000
D30 Benign neoplasm of urinary organs
0.716 0.284 0.000
D29 Benign neoplasm of male genital organs
0.716 0.284 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.716 0.284 0.000
D26 Other benign neoplasms of uterus
0.716 0.284 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.716 0.284 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.716 0.284 0.000
D19 Benign neoplasm of mesothelial tissue
0.716 0.284 0.000
D16 Benign neoplasm of bone and articular cartilage
0.716 0.284 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.716 0.284 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.716 0.284 0.000
D34 Benign neoplasm of thyroid gland
0.716 0.284 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.715 0.285 0.000
D11 Benign neoplasm of major salivary glands
0.715 0.285 0.000
N99-N99 Other disorders of the genitourinary system
0.715 0.285 0.000
N39.8 Other specified disorders of urinary system
0.715 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
Z22 Carrier of infectious disease
0.714 0.286 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.714 0.286 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.714 0.286 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.713 0.287 0.000
A80-A89 Viral infections of the central nervous system
0.710 0.290 0.000
I87.8 Other specified disorders of veins
0.710 0.290 0.000
J90-J94 Other diseases of pleura
0.710 0.290 0.000
N21 Calculus of lower urinary tract
0.709 0.291 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.709 0.291 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.709 0.291 0.000
J09-J18 Influenza and pneumonia
0.707 0.293 0.000
C18.9 Colon, unspecified
0.707 0.293 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.706 0.293 0.000
R77 Other abnormalities of plasma proteins
0.706 0.293 0.000
R76 Other abnormal immunological findings in serum
0.706 0.293 0.000
R74 Abnormal serum enzyme levels
0.706 0.293 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.706 0.293 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.706 0.293 0.000
R71 Abnormality of red blood cells
0.706 0.293 0.000
D73 Diseases of spleen
0.706 0.294 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.706 0.294 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.706 0.294 0.000
D75 Other diseases of blood and blood-forming organs
0.706 0.294 0.000
D25.1 Intramural leiomyoma of uterus
0.705 0.295 0.000
C90.0 Multiple myeloma
0.705 0.295 0.000
S42 Fracture of shoulder and upper arm
0.704 0.296 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.704 0.296 0.000
N32.8 Other specified disorders of bladder
0.704 0.296 0.000
M72 Fibroblastic disorders
0.703 0.296 0.000
I95 Hypotension
0.703 0.297 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.703 0.297 0.000
D36.7 Other specified sites
0.703 0.297 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.702 0.297 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.702 0.298 0.000
Z41 Procedures for purposes other than remedying health state
0.701 0.299 0.000
C64-C68 Malignant neoplasms of urinary tract
0.700 0.300 0.000
M80-M85 Disorders of bone density and structure
0.700 0.300 0.000
M53 Other dorsopathies, not elsewhere classified
0.698 0.302 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.698 0.302 0.000
H10-H13 Disorders of conjunctiva
0.696 0.304 0.000
M79.64 Pain in limb (Hand)
0.696 0.304 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.695 0.304 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.695 0.305 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.695 0.305 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.694 0.306 0.000
T66-T78 Other and unspecified effects of external causes
0.694 0.306 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.694 0.306 0.000
M79.69 Pain in limb (Site unspecified)
0.693 0.307 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.692 0.308 0.000
R79.0 Abnormal level of blood mineral
0.692 0.308 0.000
M79.60 Pain in limb (Multiple sites)
0.691 0.309 0.000
Z50.5 Speech therapy
0.690 0.310 0.000
H55-H59 Other disorders of eye and adnexa
0.690 0.310 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.689 0.311 0.000
Z50.2 Alcohol rehabilitation
0.689 0.311 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.689 0.311 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.689 0.311 0.000
N20.0 Calculus of kidney
0.688 0.312 0.000
Z94.8 Other transplanted organ and tissue status
0.687 0.313 0.000
I27 Other pulmonary heart diseases
0.687 0.313 0.000
Z43 Attention to artificial openings
0.686 0.314 0.000
M79.0 Rheumatism, unspecified
0.686 0.314 0.000
Z33 Pregnant state, incidental
0.686 0.314 0.000
C81 Hodgkin's disease
0.686 0.314 0.000
Z50.6 Orthoptic training
0.685 0.314 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.685 0.314 0.000
Z50.3 Drug rehabilitation
0.685 0.314 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.684 0.316 0.000
G20-G26 Extrapyramidal and movement disorders
0.684 0.316 0.000
Z45.1 Adjustment and management of infusion pump
0.682 0.318 0.000
C91 Lymphoid leukaemia
0.681 0.319 0.000
M25 Other joint disorders, not elsewhere classified
0.680 0.320 0.000
N17-N19 Renal failure
0.680 0.320 0.000
N86 Erosion and ectropion of cervix uteri
0.679 0.321 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.678 0.321 0.000
R26.3 Immobility
0.678 0.322 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.678 0.322 0.000
R26.1 Paralytic gait
0.678 0.322 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.678 0.322 0.000
B99-B99 Other infectious diseases
0.677 0.322 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.677 0.322 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.677 0.322 0.000
B65-B83 Helminthiases
0.677 0.322 0.000
B50-B64 Protozoal diseases
0.677 0.322 0.000
B15-B19 Viral hepatitis
0.677 0.322 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.677 0.322 0.000
A75-A79 Rickettsioses
0.677 0.322 0.000
A70-A74 Other diseases caused by chlamydiae
0.677 0.322 0.000
A65-A69 Other spirochaetal diseases
0.677 0.322 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.677 0.322 0.000
A20-A28 Certain zoonotic bacterial diseases
0.677 0.322 0.000
A15-A19 Tuberculosis
0.677 0.322 0.000
M67 Other disorders of synovium and tendon
0.677 0.323 0.000
R04 Haemorrhage from respiratory passages
0.677 0.323 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.676 0.324 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.675 0.325 0.000
O45 Premature separation of placenta [abruptio placentae]
0.675 0.325 0.000
O44 Placenta praevia
0.675 0.325 0.000
O43 Placental disorders
0.675 0.325 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.675 0.325 0.000
O33 Maternal care for known or suspected disproportion
0.675 0.325 0.000
O31 Complications specific to multiple gestation
0.675 0.325 0.000
O40 Polyhydramnios
0.675 0.325 0.000
N98 Complications associated with artificial fertilisation
0.673 0.327 0.000
N91 Absent, scanty and rare menstruation
0.673 0.327 0.000
N82 Fistulae involving female genital tract
0.673 0.327 0.000
N96 Habitual aborter
0.673 0.327 0.000
R45 Symptoms and signs involving emotional state
0.673 0.327 0.000
R25 Abnormal involuntary movements
0.673 0.327 0.000
M54.39 Sciatica (Site unspecified)
0.672 0.328 0.000
N37 Urethral disorders in diseases classified elsewhere
0.671 0.329 0.000
N36 Other disorders of urethra
0.671 0.329 0.000
N34 Urethritis and urethral syndrome
0.671 0.329 0.000
N33 Bladder disorders in diseases classified elsewhere
0.671 0.329 0.000
M79.10 Myalgia (Multiple sites)
0.671 0.329 0.000
Z48 Other surgical follow-up care
0.671 0.329 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.671 0.329 0.000
H54 Blindness and low vision
0.671 0.329 0.000
J98.4 Other disorders of lung
0.671 0.329 0.000
M50 Cervical disk disorders
0.670 0.329 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.670 0.330 0.000
M13 Other arthritis
0.670 0.330 0.000
D86 Sarcoidosis
0.670 0.330 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.670 0.330 0.000
G93 Other disorders of brain
0.670 0.330 0.000
H42 Glaucoma in diseases classified elsewhere
0.670 0.330 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.670 0.330 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.669 0.331 0.000
R09.1 Pleurisy
0.669 0.331 0.000
M54.5 Low back pain
0.669 0.331 0.000
D70 Agranulocytosis
0.668 0.332 0.000
N83.0 Follicular cyst of ovary
0.668 0.332 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.667 0.333 0.000
M79.79 Fibromyalgia (Site unspecified)
0.666 0.334 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.666 0.334 0.000
M51.3 Other specified intervertebral disk degeneration
0.665 0.334 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.665 0.334 0.000
M51.9 Intervertebral disk disorder, unspecified
0.665 0.334 0.000
M51.8 Other specified intervertebral disk disorders
0.665 0.334 0.000
M51.4 Schmorl's nodes
0.665 0.334 0.000
C92 Myeloid leukaemia
0.665 0.335 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.665 0.335 0.000
N39.3 Stress incontinence
0.664 0.336 0.000
F99-F99 Unspecified mental disorder
0.663 0.337 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.663 0.337 0.000
F80-F89 Disorders of psychological development
0.663 0.337 0.000
F70-F79 Mental retardation
0.663 0.337 0.000
F60-F69 Disorders of adult personality and behaviour
0.663 0.337 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.663 0.337 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.663 0.337 0.000
Z45.8 Adjustment and management of other implanted devices
0.662 0.337 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.662 0.338 0.000
Z50.8 Care involving use of rehabilitation procedures
0.662 0.338 0.000
O74 Complications of anaesthesia during labour and delivery
0.662 0.338 0.000
O73 Retained placenta and membranes, without haemorrhage
0.662 0.338 0.000
O71 Other obstetric trauma
0.662 0.338 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.662 0.338 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.662 0.338 0.000
O62 Abnormalities of forces of labour
0.662 0.338 0.000
O61 Failed induction of labour
0.662 0.338 0.000
O60 Preterm delivery
0.662 0.338 0.000
R47-R49 Symptoms and signs involving speech and voice
0.662 0.338 0.000
H30-H36 Disorders of choroid and retina
0.662 0.338 0.000
F30-F39 Mood [affective] disorders
0.662 0.338 0.000
N00-N08 Glomerular diseases
0.662 0.338 0.000
J00-J06 Acute upper respiratory infections
0.662 0.338 0.000
D23.7 Skin of lower limb, including hip
0.661 0.338 0.000
R02 Gangrene, not elsewhere classified
0.660 0.339 0.000
C51-C58 Malignant neoplasms of female genital organs
0.660 0.339 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.660 0.340 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.660 0.340 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.660 0.340 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.660 0.340 0.000
C21 Malignant neoplasm of anus and anal canal
0.660 0.340 0.000
C17 Malignant neoplasm of small intestine
0.660 0.340 0.000
C16 Malignant neoplasm of stomach
0.660 0.340 0.000
C23 Malignant neoplasm of gallbladder
0.660 0.340 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.660 0.340 0.000
C95 Leukaemia of unspecified cell type
0.660 0.340 0.000
C94 Other leukaemias of specified cell type
0.660 0.340 0.000
C93 Monocytic leukaemia
0.660 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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