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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78723535
log Bayes Factor = 19.594
Chromosome 18   position 65,161,477  (GRCh37) Explore rs78723535 on Ensembl!
Variant rs78723535 is part of Cluster X0094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
S80-S89 Injuries to the knee and lower leg
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.991 0.009 0.000
J20-J22 Other acute lower respiratory infections
0.991 0.009 0.000
I25.1 Atherosclerotic heart disease
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
J22 Unspecified acute lower respiratory infection
0.985 0.015 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.978 0.022 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.977 0.023 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.977 0.023 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.977 0.023 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.973 0.027 0.000
Chapter XI Diseases of the digestive system
0.972 0.028 0.000
Chapter XXI Factors influencing health status and contact with health services
0.969 0.031 0.000
I25.2 Old myocardial infarction
0.968 0.032 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.965 0.035 0.000
Chapter II Neoplasms
0.965 0.035 0.000
S82 Fracture of lower leg, including ankle
0.965 0.035 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.963 0.037 0.000
N10-N16 Renal tubulo-interstitial diseases
0.963 0.037 0.000
I21 Acute myocardial infarction
0.956 0.044 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.953 0.047 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.947 0.053 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.947 0.053 0.000
N20-N23 Urolithiasis
0.944 0.056 0.000
F41 Other anxiety disorders
0.944 0.056 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.941 0.059 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.939 0.061 0.000
N13 Obstructive and reflux uropathy
0.938 0.062 0.000
K50-K52 Noninfective enteritis and colitis
0.937 0.063 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.929 0.071 0.000
N17-N19 Renal failure
0.924 0.076 0.000
C15-C26 Malignant neoplasms of digestive organs
0.923 0.077 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.919 0.081 0.000
I21.4 Acute subendocardial myocardial infarction
0.916 0.084 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.916 0.084 0.000
Chapter VI Diseases of the nervous system
0.910 0.090 0.000
K50 Crohn's disease [regional enteritis]
0.910 0.090 0.000
D70 Agranulocytosis
0.907 0.093 0.000
I73 Other peripheral vascular diseases
0.904 0.096 0.000
J40-J47 Chronic lower respiratory diseases
0.903 0.097 0.000
F41.9 Anxiety disorder, unspecified
0.901 0.099 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.895 0.104 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.893 0.107 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.892 0.108 0.000
S82.1 Fracture of upper end of tibia
0.891 0.109 0.000
S82.5 Fracture of medial malleolus
0.890 0.110 0.000
K02 Dental caries
0.889 0.111 0.000
I30-I52 Other forms of heart disease
0.881 0.119 0.000
J44 Other chronic obstructive pulmonary disease
0.880 0.120 0.000
J60-J70 Lung diseases due to external agents
0.879 0.121 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.878 0.122 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.876 0.124 0.000
I35 Nonrheumatic aortic valve disorders
0.875 0.125 0.000
S81 Open wound of lower leg
0.871 0.129 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.871 0.129 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.867 0.133 0.000
I20 Angina pectoris
0.866 0.134 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.865 0.135 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.865 0.135 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.864 0.136 0.000
T82.1 Mechanical complication of cardiac electronic device
0.864 0.136 0.000
M05-M14 Inflammatory polyarthropathies
0.858 0.142 0.000
Chapter VII Diseases of the eye and adnexa
0.857 0.143 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.856 0.144 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.855 0.145 0.000
J84 Other interstitial pulmonary diseases
0.853 0.147 0.000
I21.9 Acute myocardial infarction, unspecified
0.851 0.149 0.000
I74 Arterial embolism and thrombosis
0.851 0.149 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.850 0.150 0.000
K02.9 Dental caries, unspecified
0.848 0.152 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.847 0.153 0.000
I71 Aortic aneurysm and dissection
0.845 0.155 0.000
I35.0 Aortic (valve) stenosis
0.842 0.158 0.000
N20 Calculus of kidney and ureter
0.841 0.159 0.000
K50.9 Crohn's disease, unspecified
0.841 0.159 0.000
K08 Other disorders of teeth and supporting structures
0.840 0.160 0.000
S82.10 Fracture of upper end of tibia (closed)
0.838 0.162 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.838 0.162 0.000
S82.50 Fracture of medial malleolus (closed)
0.837 0.163 0.000
I22 Subsequent myocardial infarction
0.836 0.163 0.000
W00-W19 Falls
0.836 0.164 0.000
S20-S29 Injuries to the thorax
0.833 0.167 0.000
Y43 Primarily systemic agents
0.830 0.170 0.000
N88 Other noninflammatory disorders of cervix uteri
0.829 0.171 0.000
K70-K77 Diseases of liver
0.828 0.172 0.000
K90-K93 Other diseases of the digestive system
0.828 0.172 0.000
I24 Other acute ischaemic heart diseases
0.827 0.173 0.000
N13.3 Other and unspecified hydronephrosis
0.827 0.173 0.000
K09 Cysts of oral region, not elsewhere classified
0.825 0.175 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.825 0.175 0.000
Z03.4 Observation for suspected myocardial infarction
0.824 0.176 0.000
D00-D09 In situ neoplasms
0.822 0.178 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.822 0.178 0.000
I73.9 Peripheral vascular disease, unspecified
0.819 0.181 0.000
D75 Other diseases of blood and blood-forming organs
0.819 0.181 0.000
Z03.8 Observation for other suspected diseases and conditions
0.819 0.181 0.000
K50.1 Crohn's disease of large intestine
0.819 0.181 0.000
S89 Other and unspecified injuries of lower leg
0.818 0.182 0.000
T66-T78 Other and unspecified effects of external causes
0.817 0.183 0.000
D80-D89 Certain disorders involving the immune mechanism
0.816 0.184 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.816 0.184 0.000
N23 Unspecified renal colic
0.815 0.185 0.000
C20 Malignant neoplasm of rectum
0.814 0.186 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.814 0.186 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.812 0.188 0.000
N17 Acute renal failure
0.811 0.189 0.000
Chapter XXII Codes for special purposes
0.810 0.189 0.000
C18 Malignant neoplasm of colon
0.810 0.190 0.000
J95-J99 Other diseases of the respiratory system
0.809 0.191 0.000
S60-S69 Injuries to the wrist and hand
0.807 0.193 0.000
S90-S99 Injuries to the ankle and foot
0.806 0.194 0.000
C79 Secondary malignant neoplasm of other sites
0.805 0.195 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.803 0.197 0.000
J09-J18 Influenza and pneumonia
0.802 0.198 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.799 0.201 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.798 0.202 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.795 0.205 0.000
S82.4 Fracture of fibula alone
0.795 0.205 0.000
I35.1 Aortic (valve) insufficiency
0.794 0.206 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.793 0.207 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.792 0.208 0.000
M50-M54 Other dorsopathies
0.792 0.208 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.790 0.209 0.000
K08.3 Retained dental root
0.790 0.210 0.000
C91 Lymphoid leukaemia
0.790 0.210 0.000
H53-H54 Visual disturbances and blindness
0.789 0.211 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.788 0.212 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.788 0.212 0.000
Z29 Need for other prophylactic measures
0.786 0.214 0.000
I77 Other disorders of arteries and arterioles
0.786 0.214 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.785 0.215 0.000
M65-M68 Disorders of synovium and tendon
0.784 0.216 0.000
S70-S79 Injuries to the hip and thigh
0.780 0.220 0.000
N18 Chronic renal failure
0.780 0.220 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.779 0.221 0.000
S80 Superficial injury of lower leg
0.778 0.222 0.000
Z60 Problems related to social environment
0.778 0.222 0.000
H55-H59 Other disorders of eye and adnexa
0.777 0.223 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.776 0.224 0.000
N20.1 Calculus of ureter
0.775 0.225 0.000
F80-F89 Disorders of psychological development
0.774 0.226 0.000
Z22 Carrier of infectious disease
0.773 0.227 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.771 0.229 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.771 0.229 0.000
N92 Excessive, frequent and irregular menstruation
0.770 0.230 0.000
I50 Heart failure
0.769 0.231 0.000
N00-N08 Glomerular diseases
0.768 0.232 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.768 0.232 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.767 0.233 0.000
G40-G47 Episodic and paroxysmal disorders
0.767 0.233 0.000
M06 Other rheumatoid arthritis
0.767 0.233 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.766 0.234 0.000
T79-T79 Certain early complications of trauma
0.766 0.234 0.000
M80-M85 Disorders of bone density and structure
0.765 0.235 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.765 0.235 0.000
N84 Polyp of female genital tract
0.765 0.235 0.000
J81 Pulmonary oedema
0.764 0.236 0.000
F40 Phobic anxiety disorders
0.763 0.237 0.000
F41.2 Mixed anxiety and depressive disorder
0.763 0.237 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.762 0.238 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.762 0.238 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.761 0.239 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.760 0.240 0.000
N13.4 Hydroureter
0.759 0.240 0.000
S81.8 Open wound of other parts of lower leg
0.759 0.241 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.759 0.241 0.000
N87 Dysplasia of cervix uteri
0.757 0.243 0.000
K51 Ulcerative colitis
0.757 0.243 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.755 0.245 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.753 0.247 0.000
Y57 Other and unspecified drugs and medicaments
0.752 0.248 0.000
J80 Adult respiratory distress syndrome
0.752 0.248 0.000
C15 Malignant neoplasm of oesophagus
0.752 0.248 0.000
Z72 Problems related to lifestyle
0.752 0.248 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.751 0.249 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.751 0.249 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.749 0.251 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.748 0.252 0.000
D55-D59 Haemolytic anaemias
0.747 0.253 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.746 0.254 0.000
K14 Diseases of tongue
0.745 0.255 0.000
K65-K67 Diseases of peritoneum
0.744 0.256 0.000
M45-M49 Spondylopathies
0.744 0.256 0.000
I73.0 Raynaud's syndrome
0.744 0.256 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.743 0.256 0.000
N21 Calculus of lower urinary tract
0.743 0.257 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.743 0.257 0.000
I20.0 Unstable angina
0.743 0.257 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.741 0.259 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.741 0.259 0.000
N99-N99 Other disorders of the genitourinary system
0.740 0.259 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.740 0.260 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.739 0.261 0.000
M40-M43 Deforming dorsopathies
0.738 0.261 0.000
F17.2 Dependence syndrome
0.739 0.261 0.000
K09.0 Developmental odontogenic cysts
0.737 0.262 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.737 0.262 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.736 0.264 0.000
N25-N29 Other disorders of kidney and ureter
0.736 0.264 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.735 0.265 0.000
I50.1 Left ventricular failure
0.735 0.265 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.734 0.266 0.000
Y43.3 Other antineoplastic drugs
0.734 0.266 0.000
C77.5 Intrapelvic lymph nodes
0.734 0.266 0.000
F41.1 Generalised anxiety disorder
0.732 0.268 0.000
X60-X84 Intentional self-harm
0.732 0.268 0.000
N17.9 Acute renal failure, unspecified
0.731 0.269 0.000
K50.8 Other Crohn's disease
0.728 0.272 0.000
Y42.7 Androgens and anabolic congeners
0.728 0.272 0.000
J00-J06 Acute upper respiratory infections
0.728 0.272 0.000
I70 Atherosclerosis
0.727 0.273 0.000
K00 Disorders of tooth development and eruption
0.727 0.273 0.000
D69 Purpura and other haemorrhagic conditions
0.726 0.274 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.725 0.275 0.000
I20.8 Other forms of angina pectoris
0.725 0.275 0.000
J69 Pneumonitis due to solids and liquids
0.724 0.276 0.000
N90.4 Leukoplakia of vulva
0.724 0.276 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.723 0.277 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.723 0.277 0.000
I24.8 Other forms of acute ischaemic heart disease
0.722 0.278 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.720 0.280 0.000
I99 Other and unspecified disorders of circulatory system
0.720 0.280 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.719 0.281 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
G47 Sleep disorders
0.716 0.284 0.000
Z60.2 Living alone
0.716 0.284 0.000
C91.1 Chronic lymphocytic leukaemia
0.716 0.284 0.000
C51-C58 Malignant neoplasms of female genital organs
0.716 0.284 0.000
D75.1 Secondary polycythaemia
0.715 0.285 0.000
N86 Erosion and ectropion of cervix uteri
0.715 0.285 0.000
Y44 Agents primarily affecting blood constituents
0.714 0.286 0.000
T87 Complications peculiar to reattachment and amputation
0.714 0.286 0.000
T86 Failure and rejection of transplanted organs and tissues
0.714 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.714 0.286 0.000
C50-C50 Malignant neoplasm of breast
0.713 0.287 0.000
S88 Traumatic amputation of lower leg
0.713 0.287 0.000
S87 Crushing injury of lower leg
0.713 0.287 0.000
S86 Injury of muscle and tendon at lower leg level
0.713 0.287 0.000
S85 Injury of blood vessels at lower leg level
0.713 0.287 0.000
S84 Injury of nerves at lower leg level
0.713 0.287 0.000
D72 Other disorders of white blood cells
0.713 0.287 0.000
Z72.0 Tobacco use
0.712 0.288 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.711 0.289 0.000
F99-F99 Unspecified mental disorder
0.711 0.289 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.711 0.289 0.000
F70-F79 Mental retardation
0.711 0.289 0.000
F60-F69 Disorders of adult personality and behaviour
0.711 0.289 0.000
J21 Acute bronchiolitis
0.711 0.289 0.000
J20 Acute bronchitis
0.711 0.289 0.000
M05 Seropositive rheumatoid arthritis
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.707 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.292 0.000
Y10-Y34 Event of undetermined intent
0.707 0.292 0.000
Y00-Y09 Assault
0.707 0.292 0.000
X85-X99 Assault
0.707 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.292 0.000
X50-X57 Overexertion, travel and privation
0.707 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.707 0.292 0.000
X30-X39 Exposure to forces of nature
0.707 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.292 0.000
X10-X19 Contact with heat and hot substances
0.707 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.292 0.000
W75-W84 Other accidental threats to breathing
0.707 0.292 0.000
W65-W74 Accidental drowning and submersion
0.707 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.707 0.292 0.000
V95-V97 Air and space transport accidents
0.707 0.292 0.000
V90-V94 Water transport accidents
0.707 0.292 0.000
V80-V89 Other land transport accidents
0.707 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.707 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.707 0.292 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.707 0.293 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.707 0.293 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.706 0.294 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.705 0.295 0.000
K12 Stomatitis and related lesions
0.704 0.296 0.000
N19 Unspecified renal failure
0.703 0.297 0.000
M86-M90 Other osteopathies
0.703 0.297 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.703 0.297 0.000
G47.9 Sleep disorder, unspecified
0.703 0.297 0.000
S82.2 Fracture of shaft of tibia
0.702 0.298 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.702 0.298 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.701 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.701 0.299 0.000
I72 Other aneurysm
0.701 0.299 0.000
C92 Myeloid leukaemia
0.700 0.300 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.700 0.300 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.700 0.300 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.700 0.300 0.000
T82.3 Mechanical complication of other vascular grafts
0.700 0.300 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.700 0.300 0.000
K91.4 Colostomy and enterostomy malfunction
0.700 0.300 0.000
J43 Emphysema
0.698 0.302 0.000
N90.7 Vulvar cyst
0.698 0.302 0.000
K11 Diseases of salivary glands
0.697 0.303 0.000
I35.8 Other aortic valve disorders
0.697 0.303 0.000
J46 Status asthmaticus
0.697 0.303 0.000
H57 Other disorders of eye and adnexa
0.696 0.304 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.696 0.304 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.696 0.304 0.000
D68 Other coagulation defects
0.696 0.304 0.000
W20-W49 Exposure to inanimate mechanical forces
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.695 0.305 0.000
I25.5 Ischaemic cardiomyopathy
0.693 0.307 0.000
N10 Acute tubulo-interstitial nephritis
0.693 0.307 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.692 0.308 0.000
H53 Visual disturbances
0.692 0.308 0.000
Y59 Other and unspecified vaccines and biological substances
0.692 0.308 0.000
Y58 Bacterial vaccines
0.692 0.308 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.692 0.308 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.692 0.308 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.692 0.308 0.000
Y52 Agents primarily affecting the cardiovascular system
0.692 0.308 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.692 0.308 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
Y48 Anaesthetics and therapeutic gases
0.692 0.308 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.692 0.308 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.692 0.308 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
D86 Sarcoidosis
0.692 0.308 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.692 0.308 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.692 0.308 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.692 0.308 0.000
S82.9 Fracture of lower leg, part unspecified
0.692 0.308 0.000
S82.7 Multiple fractures of lower leg
0.692 0.308 0.000
S82.0 Fracture of patella
0.692 0.308 0.000
S89.9 Unspecified injury of lower leg
0.691 0.309 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.691 0.309 0.000
F48 Other neurotic disorders
0.691 0.309 0.000
F44 Dissociative [conversion] disorders
0.691 0.309 0.000
F42 Obsessive-compulsive disorder
0.691 0.309 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.690 0.309 0.000
N15 Other renal tubulo-interstitial diseases
0.690 0.309 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.690 0.309 0.000
N11 Chronic tubulo-interstitial nephritis
0.690 0.309 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.690 0.310 0.000
Z95.2 Presence of prosthetic heart valve
0.689 0.311 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.688 0.312 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.688 0.312 0.000
K07 Dentofacial anomalies [including malocclusion]
0.687 0.313 0.000
N84.1 Polyp of cervix uteri
0.687 0.313 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.686 0.314 0.000
G30-G32 Other degenerative diseases of the nervous system
0.686 0.314 0.000
T78 Adverse effects, not elsewhere classified
0.686 0.314 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.686 0.314 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.686 0.314 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.685 0.315 0.000
Z22.3 Carrier of other specified bacterial diseases
0.685 0.315 0.000
M65 Synovitis and tenosynovitis
0.685 0.315 0.000
N98 Complications associated with artificial fertilisation
0.683 0.317 0.000
N91 Absent, scanty and rare menstruation
0.683 0.317 0.000
N82 Fistulae involving female genital tract
0.683 0.317 0.000
N96 Habitual aborter
0.683 0.317 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.683 0.317 0.000
C78.7 Secondary malignant neoplasm of liver
0.683 0.317 0.000
S40-S49 Injuries to the shoulder and upper arm
0.683 0.317 0.000
M06.9 Rheumatoid arthritis, unspecified
0.682 0.318 0.000
C81 Hodgkin's disease
0.682 0.318 0.000
J98 Other respiratory disorders
0.682 0.318 0.000
N13.8 Other obstructive and reflux uropathy
0.681 0.319 0.000
N88.2 Stricture and stenosis of cervix uteri
0.681 0.319 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.681 0.319 0.000
S20 Superficial injury of thorax
0.680 0.320 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.679 0.321 0.000
D74 Methaemoglobinaemia
0.679 0.321 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.679 0.321 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.679 0.321 0.000
K10 Other diseases of jaws
0.679 0.321 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.679 0.321 0.000
K03 Other diseases of hard tissues of teeth
0.679 0.321 0.000
F10.2 Dependence syndrome
0.678 0.322 0.000
K76 Other diseases of liver
0.678 0.322 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.678 0.322 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.677 0.323 0.000
H54 Blindness and low vision
0.677 0.323 0.000
F41.8 Other specified anxiety disorders
0.677 0.323 0.000
F41.3 Other mixed anxiety disorders
0.677 0.323 0.000
S81.0 Open wound of knee
0.676 0.324 0.000
S82.3 Fracture of lower end of tibia
0.676 0.324 0.000
D04 Carcinoma in situ of skin
0.675 0.325 0.000
I33 Acute and subacute endocarditis
0.675 0.325 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.675 0.325 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.674 0.326 0.000
M91-M94 Chondropathies
0.673 0.326 0.000
M60-M63 Disorders of muscles
0.673 0.326 0.000
M00-M03 Infectious arthropathies
0.673 0.326 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.673 0.327 0.000
N13.6 Pyonephrosis
0.673 0.327 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.673 0.327 0.000
S82.40 Fracture of fibula alone (closed)
0.673 0.327 0.000
N94.1 Dyspareunia
0.673 0.327 0.000
N20.2 Calculus of kidney with calculus of ureter
0.672 0.327 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.672 0.328 0.000
Z93 Artificial opening status
0.670 0.330 0.000
N18.9 Chronic renal failure, unspecified
0.669 0.331 0.000
D06 Carcinoma in situ of cervix uteri
0.668 0.332 0.000
T81 Complications of procedures, not elsewhere classified
0.667 0.333 0.000
S32 Fracture of lumbar spine and pelvis
0.666 0.334 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.666 0.334 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.666 0.334 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.666 0.334 0.000
Z29.1 Prophylactic immunotherapy
0.665 0.334 0.000
S00-S09 Injuries to the head
0.665 0.335 0.000
G70-G73 Diseases of myoneural junction and muscle
0.664 0.335 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.664 0.336 0.000
J18 Pneumonia, organism unspecified
0.664 0.336 0.000
J90-J94 Other diseases of pleura
0.664 0.336 0.000
W13 Fall from, out of or through building or structure
0.664 0.336 0.000
Y40 Systemic antibiotics
0.662 0.338 0.000
G20-G26 Extrapyramidal and movement disorders
0.662 0.338 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.662 0.338 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.662 0.338 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.662 0.338 0.000
C21 Malignant neoplasm of anus and anal canal
0.662 0.338 0.000
C17 Malignant neoplasm of small intestine
0.662 0.338 0.000
C23 Malignant neoplasm of gallbladder
0.662 0.338 0.000
I74.5 Embolism and thrombosis of iliac artery
0.661 0.339 0.000
M07 Psoriatic and enteropathic arthropathies
0.661 0.339 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.660 0.340 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.660 0.340 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.660 0.340 0.000
K35-K38 Diseases of appendix
0.659 0.341 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.659 0.341 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.659 0.341 0.000
Z03.1 Observation for suspected malignant neoplasm
0.658 0.342 0.000
K70 Alcoholic liver disease
0.658 0.342 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.658 0.342 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.656 0.343 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.656 0.343 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.656 0.343 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.656 0.343 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.656 0.343 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.656 0.343 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.656 0.343 0.000
F11 Mental and behavioural disorders due to use of opioids
0.656 0.343 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.656 0.344 0.000
I95 Hypotension
0.656 0.344 0.000
Z57 Occupational exposure to risk-factors
0.655 0.345 0.000
F43 Reaction to severe stress, and adjustment disorders
0.654 0.345 0.000
C78.2 Secondary malignant neoplasm of pleura
0.654 0.346 0.000
M54 Dorsalgia
0.654 0.346 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.653 0.347 0.000
C16 Malignant neoplasm of stomach
0.653 0.347 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.653 0.347 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.652 0.348 0.000
I71.0 Dissection of aorta [any part]
0.652 0.348 0.000
N81 Female genital prolapse
0.651 0.349 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.650 0.350 0.000
F17.1 Harmful use
0.649 0.351 0.000
I73.8 Other specified peripheral vascular diseases
0.648 0.352 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.648 0.352 0.000
J41 Simple and mucopurulent chronic bronchitis
0.648 0.352 0.000
J42 Unspecified chronic bronchitis
0.648 0.352 0.000
K05 Gingivitis and periodontal diseases
0.647 0.353 0.000
M11 Other crystal arthropathies
0.647 0.353 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.647 0.353 0.000
I05-I09 Chronic rheumatic heart diseases
0.646 0.354 0.000
C18.6 Descending colon
0.646 0.354 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.645 0.355 0.000
I77.1 Stricture of artery
0.645 0.355 0.000
N87.0 Mild cervical dysplasia
0.644 0.356 0.000
N89 Other noninflammatory disorders of vagina
0.643 0.356 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.642 0.358 0.000
Z28 Immunisation not carried out
0.642 0.358 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.642 0.358 0.000
Z26 Need for immunisation against other single infectious diseases
0.642 0.358 0.000
Z25 Need for immunisation against other single viral diseases
0.642 0.358 0.000
Z24 Need for immunisation against certain single viral diseases
0.642 0.358 0.000
Z23 Need for immunisation against single bacterial diseases
0.642 0.358 0.000
Z20 Contact with and exposure to communicable diseases
0.642 0.358 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.642 0.358 0.000
Chapter I Certain infectious and parasitic diseases
0.641 0.359 0.000
W10 Fall on and from stairs and steps
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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