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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78743131
log Bayes Factor = 0.586096
Chromosome 1   position 182,721,899  (GRCh37) Explore rs78743131 on Ensembl!
Variant rs78743131 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
0.738 0.262 0.000
I30-I52 Other forms of heart disease
0.735 0.265 0.000
# Top node
0.713 0.287 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.713 0.287 0.000
I50 Heart failure
0.708 0.292 0.000
M45-M49 Spondylopathies
0.688 0.312 0.000
I05-I09 Chronic rheumatic heart diseases
0.673 0.327 0.000
Chapter II Neoplasms
0.671 0.329 0.000
I34 Nonrheumatic mitral valve disorders
0.669 0.331 0.000
I50.0 Congestive heart failure
0.662 0.338 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.659 0.341 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.659 0.341 0.000
I50.1 Left ventricular failure
0.657 0.343 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.647 0.353 0.000
M47 Spondylosis
0.645 0.355 0.000
M50-M54 Other dorsopathies
0.641 0.359 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.632 0.368 0.000
Chapter X Diseases of the respiratory system
0.631 0.369 0.000
I08 Multiple valve diseases
0.626 0.374 0.000
I20-I25 Ischaemic heart diseases
0.612 0.388 0.000
I51 Complications and ill-defined descriptions of heart disease
0.606 0.394 0.000
Chapter VIII Diseases of the ear and mastoid process
0.603 0.397 0.000
M05-M14 Inflammatory polyarthropathies
0.598 0.402 0.000
I49 Other cardiac arrhythmias
0.598 0.402 0.000
I31 Other diseases of pericardium
0.596 0.404 0.000
M70-M79 Other soft tissue disorders
0.595 0.405 0.000
M15-M19 Arthrosis
0.587 0.413 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.586 0.414 0.000
I34.1 Mitral (valve) prolapse
0.584 0.416 0.000
M47.8 Other spondylosis
0.583 0.417 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.582 0.418 0.000
J00-J06 Acute upper respiratory infections
0.582 0.418 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.581 0.419 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.581 0.419 0.000
I60-I69 Cerebrovascular diseases
0.580 0.420 0.000
M54 Dorsalgia
0.577 0.423 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.571 0.429 0.000
C51-C58 Malignant neoplasms of female genital organs
0.571 0.429 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.568 0.432 0.000
I38 Endocarditis, valve unspecified
0.567 0.433 0.000
M86-M90 Other osteopathies
0.565 0.435 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.565 0.435 0.000
M19 Other arthrosis
0.564 0.436 0.000
I34.0 Mitral (valve) insufficiency
0.563 0.437 0.000
M46 Other inflammatory spondylopathies
0.562 0.437 0.000
M48 Other spondylopathies
0.561 0.439 0.000
I44 Atrioventricular and left bundle-branch block
0.561 0.439 0.000
C15-C26 Malignant neoplasms of digestive organs
0.561 0.439 0.000
D00-D09 In situ neoplasms
0.559 0.441 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.558 0.442 0.000
M47.2 Other spondylosis with radiculopathy
0.558 0.442 0.000
I26 Pulmonary embolism
0.556 0.444 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.551 0.449 0.000
M80-M85 Disorders of bone density and structure
0.549 0.451 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.546 0.454 0.000
I73 Other peripheral vascular diseases
0.546 0.454 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.542 0.458 0.000
M19.9 Arthrosis, unspecified
0.541 0.459 0.000
M75 Shoulder lesions
0.541 0.459 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.539 0.461 0.000
I46 Cardiac arrest
0.537 0.462 0.000
H65-H75 Diseases of middle ear and mastoid
0.536 0.464 0.000
D50-D53 Nutritional anaemias
0.535 0.465 0.000
I35 Nonrheumatic aortic valve disorders
0.534 0.466 0.000
M54.5 Low back pain
0.532 0.468 0.000
I08.0 Disorders of both mitral and aortic valves
0.530 0.470 0.000
J95-J99 Other diseases of the respiratory system
0.529 0.471 0.000
I00-I02 Acute rheumatic fever
0.529 0.471 0.000
I52 Other heart disorders in diseases classified elsewhere
0.527 0.473 0.000
I48 Atrial fibrillation and flutter
0.527 0.473 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.527 0.473 0.000
I41 Myocarditis in diseases classified elsewhere
0.527 0.473 0.000
I40 Acute myocarditis
0.527 0.473 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.527 0.473 0.000
I37 Pulmonary valve disorders
0.527 0.473 0.000
I36 Nonrheumatic tricuspid valve disorders
0.527 0.473 0.000
I33 Acute and subacute endocarditis
0.527 0.473 0.000
I32 Pericarditis in diseases classified elsewhere
0.527 0.473 0.000
I30 Acute pericarditis
0.527 0.473 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.524 0.476 0.000
I71 Aortic aneurysm and dissection
0.524 0.476 0.000
I49.4 Other and unspecified premature depolarisation
0.518 0.482 0.000
M50 Cervical disk disorders
0.517 0.482 0.000
M40-M43 Deforming dorsopathies
0.517 0.483 0.000
C71 Malignant neoplasm of brain
0.516 0.484 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.516 0.484 0.000
M47.82 Other spondylosis (Cervical region)
0.514 0.486 0.000
Chapter XXII Codes for special purposes
0.511 0.488 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.511 0.488 0.000
M91-M94 Chondropathies
0.511 0.489 0.000
M60-M63 Disorders of muscles
0.511 0.489 0.000
M00-M03 Infectious arthropathies
0.511 0.489 0.000
D80-D89 Certain disorders involving the immune mechanism
0.509 0.491 0.000
O60-O75 Complications of labour and delivery
0.504 0.496 0.000
C18 Malignant neoplasm of colon
0.502 0.498 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.502 0.498 0.000
I77 Other disorders of arteries and arterioles
0.502 0.498 0.000
D10-D36 Benign neoplasms
0.501 0.499 0.000
M54.56 Low back pain (Lumbar region)
0.501 0.499 0.000
D68 Other coagulation defects
0.499 0.501 0.000
M06 Other rheumatoid arthritis
0.499 0.501 0.000
I21 Acute myocardial infarction
0.498 0.502 0.000
O00-O08 Pregnancy with abortive outcome
0.497 0.503 0.000
I25 Chronic ischaemic heart disease
0.497 0.503 0.000
I51.7 Cardiomegaly
0.496 0.504 0.000
C50-C50 Malignant neoplasm of breast
0.496 0.504 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.495 0.505 0.000
I51.9 Heart disease, unspecified
0.494 0.506 0.000
M49 Spondylopathies in diseases classified elsewhere
0.493 0.507 0.000
M45 Ankylosing spondylitis
0.493 0.507 0.000
I73.9 Peripheral vascular disease, unspecified
0.492 0.508 0.000
J60-J70 Lung diseases due to external agents
0.492 0.508 0.000
J01 Acute sinusitis
0.489 0.511 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.488 0.512 0.000
I42 Cardiomyopathy
0.486 0.514 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.486 0.514 0.000
Chapter XX External causes of morbidity and mortality
0.485 0.515 0.000
M75.4 Impingement syndrome of shoulder
0.484 0.516 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.483 0.517 0.000
I09 Other rheumatic heart diseases
0.482 0.517 0.000
I07 Rheumatic tricuspid valve diseases
0.482 0.517 0.000
I06 Rheumatic aortic valve diseases
0.482 0.517 0.000
I05 Rheumatic mitral valve diseases
0.482 0.517 0.000
I22 Subsequent myocardial infarction
0.482 0.518 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.481 0.519 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.481 0.519 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.481 0.519 0.000
I45 Other conduction disorders
0.480 0.520 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.480 0.520 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.480 0.520 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.480 0.520 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.479 0.521 0.000
M47.86 Other spondylosis (Lumbar region)
0.479 0.521 0.000
D05 Carcinoma in situ of breast
0.478 0.522 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.475 0.525 0.000
O47 False labour
0.474 0.526 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.473 0.527 0.000
O85-O92 Complications predominantly related to the puerperium
0.472 0.527 0.000
D55-D59 Haemolytic anaemias
0.472 0.528 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.471 0.529 0.000
M48.0 Spinal stenosis
0.470 0.530 0.000
I31.3 Pericardial effusion (noninflammatory)
0.470 0.530 0.000
C91 Lymphoid leukaemia
0.470 0.530 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.470 0.530 0.000
J03 Acute tonsillitis
0.469 0.531 0.000
I44.0 Atrioventricular block, first degree
0.468 0.532 0.000
O36 Maternal care for other known or suspected foetal problems
0.466 0.534 0.000
C56 Malignant neoplasm of ovary
0.465 0.534 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.464 0.536 0.000
I72 Other aneurysm
0.464 0.536 0.000
I70 Atherosclerosis
0.464 0.536 0.000
I31.9 Disease of pericardium, unspecified
0.464 0.536 0.000
H71 Cholesteatoma of middle ear
0.463 0.536 0.000
M47.1 Other spondylosis with myelopathy
0.463 0.537 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.463 0.537 0.000
I78 Diseases of capillaries
0.462 0.537 0.000
O80-O84 Delivery
0.461 0.539 0.000
C54 Malignant neoplasm of corpus uteri
0.460 0.540 0.000
M53 Other dorsopathies, not elsewhere classified
0.460 0.540 0.000
M65-M68 Disorders of synovium and tendon
0.459 0.541 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.458 0.542 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.457 0.543 0.000
I67 Other cerebrovascular diseases
0.456 0.544 0.000
M47.9 Spondylosis, unspecified
0.455 0.544 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.455 0.545 0.000
C71.2 Temporal lobe
0.454 0.546 0.000
Chapter V Mental and behavioural disorders
0.454 0.546 0.000
I27 Other pulmonary heart diseases
0.453 0.547 0.000
I28 Other diseases of pulmonary vessels
0.453 0.547 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.453 0.547 0.000
I80 Phlebitis and thrombophlebitis
0.452 0.547 0.000
D45 Polycythaemia vera
0.452 0.548 0.000
J20-J22 Other acute lower respiratory infections
0.452 0.548 0.000
M05 Seropositive rheumatoid arthritis
0.452 0.548 0.000
M54.9 Dorsalgia, unspecified
0.451 0.549 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.450 0.550 0.000
I08.9 Multiple valve disease, unspecified
0.449 0.551 0.000
I08.8 Other multiple valve diseases
0.449 0.551 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.449 0.551 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.449 0.551 0.000
I21.9 Acute myocardial infarction, unspecified
0.448 0.552 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.448 0.552 0.000
M50.2 Other cervical disk displacement
0.447 0.553 0.000
D50 Iron deficiency anaemia
0.447 0.553 0.000
J98 Other respiratory disorders
0.446 0.554 0.000
C15 Malignant neoplasm of oesophagus
0.446 0.554 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.445 0.555 0.000
M13 Other arthritis
0.443 0.557 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.442 0.558 0.000
M75.0 Adhesive capsulitis of shoulder
0.442 0.558 0.000
M19.0 Primary arthrosis of other joints
0.441 0.558 0.000
S60-S69 Injuries to the wrist and hand
0.441 0.559 0.000
M89 Other disorders of bone
0.441 0.559 0.000
O42 Premature rupture of membranes
0.441 0.559 0.000
I25.2 Old myocardial infarction
0.441 0.559 0.000
C92 Myeloid leukaemia
0.440 0.560 0.000
S20-S29 Injuries to the thorax
0.439 0.561 0.000
I23 Certain current complications following acute myocardial infarction
0.439 0.561 0.000
O48 Prolonged pregnancy
0.438 0.562 0.000
I63 Cerebral infarction
0.437 0.563 0.000
J40-J47 Chronic lower respiratory diseases
0.437 0.563 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.436 0.564 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.435 0.564 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.435 0.565 0.000
I51.6 Cardiovascular disease, unspecified
0.434 0.565 0.000
I51.5 Myocardial degeneration
0.434 0.565 0.000
I51.4 Myocarditis, unspecified
0.434 0.565 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.434 0.565 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.434 0.565 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.434 0.565 0.000
I51.0 Cardiac septal defect, acquired
0.434 0.565 0.000
H60-H62 Diseases of external ear
0.433 0.567 0.000
O70 Perineal laceration during delivery
0.433 0.567 0.000
I84 Haemorrhoids
0.432 0.568 0.000
I83 Varicose veins of lower extremities
0.431 0.569 0.000
D69 Purpura and other haemorrhagic conditions
0.431 0.569 0.000
H90-H95 Other disorders of ear
0.431 0.569 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.431 0.569 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.431 0.569 0.000
C18.0 Caecum
0.431 0.569 0.000
M51 Other intervertebral disk disorders
0.430 0.570 0.000
O30 Multiple gestation
0.430 0.570 0.000
D73 Diseases of spleen
0.430 0.570 0.000
M14 Arthropathies in other diseases classified elsewhere
0.429 0.571 0.000
M12 Other specific arthropathies
0.429 0.571 0.000
M11 Other crystal arthropathies
0.429 0.571 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.429 0.571 0.000
M08 Juvenile arthritis
0.429 0.571 0.000
M07 Psoriatic and enteropathic arthropathies
0.429 0.571 0.000
I49.5 Sick sinus syndrome
0.429 0.571 0.000
I49.3 Ventricular premature depolarisation
0.429 0.571 0.000
I49.2 Junctional premature depolarisation
0.429 0.571 0.000
I49.1 Atrial premature depolarisation
0.429 0.571 0.000
I49.0 Ventricular fibrillation and flutter
0.429 0.571 0.000
I74 Arterial embolism and thrombosis
0.429 0.571 0.000
M19.98 Arthrosis, unspecified (Other)
0.429 0.571 0.000
M87 Osteonecrosis
0.428 0.571 0.000
M06.9 Rheumatoid arthritis, unspecified
0.428 0.572 0.000
I49.8 Other specified cardiac arrhythmias
0.428 0.572 0.000
I31.8 Other specified diseases of pericardium
0.428 0.572 0.000
I31.2 Haemopericardium, not elsewhere classified
0.428 0.572 0.000
I31.1 Chronic constrictive pericarditis
0.428 0.572 0.000
I31.0 Chronic adhesive pericarditis
0.428 0.572 0.000
D12.3 Transverse colon
0.428 0.572 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.427 0.573 0.000
M77 Other enthesopathies
0.427 0.573 0.000
M76 Enthesopathies of lower limb, excluding foot
0.427 0.573 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.427 0.573 0.000
M71 Other bursopathies
0.427 0.573 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.427 0.573 0.000
I85 Oesophageal varices
0.425 0.575 0.000
I35.1 Aortic (valve) insufficiency
0.424 0.576 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.424 0.576 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.423 0.577 0.000
J02 Acute pharyngitis
0.423 0.577 0.000
J01.9 Acute sinusitis, unspecified
0.423 0.577 0.000
M10 Gout
0.421 0.578 0.000
M15 Polyarthrosis
0.421 0.579 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.420 0.580 0.000
C95 Leukaemia of unspecified cell type
0.420 0.580 0.000
C94 Other leukaemias of specified cell type
0.420 0.580 0.000
C93 Monocytic leukaemia
0.420 0.580 0.000
C88 Malignant immunoproliferative diseases
0.420 0.580 0.000
C86 Other specified types of T/NK-cell lymphoma
0.420 0.580 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.420 0.580 0.000
C81 Hodgkin's disease
0.420 0.580 0.000
D72 Other disorders of white blood cells
0.420 0.580 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.419 0.581 0.000
H72 Perforation of tympanic membrane
0.419 0.581 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.419 0.581 0.000
M47.89 Other spondylosis (Site unspecified)
0.418 0.581 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.418 0.581 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.418 0.581 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.418 0.581 0.000
M47.84 Other spondylosis (Thoracic region)
0.418 0.581 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.418 0.581 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.418 0.581 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.418 0.581 0.000
J06.9 Acute upper respiratory infection, unspecified
0.418 0.582 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.417 0.582 0.000
D46 Myelodysplastic syndromes
0.417 0.582 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.417 0.582 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.417 0.582 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.417 0.582 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.417 0.582 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.417 0.582 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.417 0.582 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.417 0.583 0.000
J04 Acute laryngitis and tracheitis
0.417 0.583 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.417 0.583 0.000
J00 Acute nasopharyngitis [common cold]
0.417 0.583 0.000
I88 Nonspecific lymphadenitis
0.417 0.583 0.000
I87 Other disorders of veins
0.417 0.583 0.000
I86 Varicose veins of other sites
0.417 0.583 0.000
I82 Other venous embolism and thrombosis
0.417 0.583 0.000
I81 Portal vein thrombosis
0.417 0.583 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.417 0.583 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.416 0.583 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.416 0.584 0.000
C70 Malignant neoplasm of meninges
0.416 0.584 0.000
C69 Malignant neoplasm of eye and adnexa
0.416 0.584 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.416 0.584 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.416 0.584 0.000
I62 Other nontraumatic intracranial haemorrhage
0.416 0.584 0.000
D68.2 Hereditary deficiency of other clotting factors
0.415 0.585 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.415 0.585 0.000
M85 Other disorders of bone density and structure
0.415 0.585 0.000
S00-S09 Injuries to the head
0.414 0.585 0.000
M54.8 Other dorsalgia
0.414 0.586 0.000
M54.6 Pain in thoracic spine
0.414 0.586 0.000
M54.4 Lumbago with sciatica
0.414 0.586 0.000
M54.1 Radiculopathy
0.414 0.586 0.000
M54.0 Panniculitis affecting regions of neck and back
0.414 0.586 0.000
M81 Osteoporosis without pathological fracture
0.413 0.586 0.000
D68.9 Coagulation defect, unspecified
0.412 0.587 0.000
I60 Subarachnoid haemorrhage
0.411 0.589 0.000
S80-S89 Injuries to the knee and lower leg
0.411 0.589 0.000
D67 Hereditary factor IX deficiency
0.410 0.590 0.000
D66 Hereditary factor VIII deficiency
0.410 0.590 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.410 0.590 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.409 0.591 0.000
C53 Malignant neoplasm of cervix uteri
0.409 0.591 0.000
C51 Malignant neoplasm of vulva
0.409 0.591 0.000
C58 Malignant neoplasm of placenta
0.409 0.591 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.409 0.591 0.000
C52 Malignant neoplasm of vagina
0.409 0.591 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.409 0.591 0.000
I69 Sequelae of cerebrovascular disease
0.408 0.592 0.000
O45 Premature separation of placenta [abruptio placentae]
0.407 0.593 0.000
O44 Placenta praevia
0.407 0.593 0.000
O43 Placental disorders
0.407 0.593 0.000
O41 Other disorders of amniotic fluid and membranes
0.407 0.593 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.407 0.593 0.000
O33 Maternal care for known or suspected disproportion
0.407 0.593 0.000
O31 Complications specific to multiple gestation
0.407 0.593 0.000
O40 Polyhydramnios
0.407 0.593 0.000
D70 Agranulocytosis
0.407 0.593 0.000
C71.9 Brain, unspecified
0.406 0.594 0.000
M90 Osteopathies in diseases classified elsewhere
0.405 0.595 0.000
M88 Paget's disease of bone [osteitis deformans]
0.405 0.595 0.000
M86 Osteomyelitis
0.405 0.595 0.000
J09-J18 Influenza and pneumonia
0.405 0.595 0.000
I24 Other acute ischaemic heart diseases
0.404 0.595 0.000
D50.8 Other iron deficiency anaemias
0.404 0.596 0.000
Chapter VI Diseases of the nervous system
0.404 0.596 0.000
M19.8 Other specified arthrosis
0.404 0.596 0.000
M19.2 Other secondary arthrosis
0.404 0.596 0.000
M19.1 Posttraumatic arthrosis of other joints
0.404 0.596 0.000
M75.3 Calcific tendinitis of shoulder
0.404 0.596 0.000
D05.0 Lobular carcinoma in situ
0.404 0.596 0.000
M46.8 Other specified inflammatory spondylopathies
0.403 0.597 0.000
M46.5 Other infective spondylopathies
0.403 0.597 0.000
M46.4 Discitis, unspecified
0.403 0.597 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.403 0.597 0.000
M46.2 Osteomyelitis of vertebra
0.403 0.597 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.403 0.597 0.000
M46.0 Spinal enthesopathy
0.403 0.597 0.000
M72 Fibroblastic disorders
0.403 0.597 0.000
H80-H83 Diseases of inner ear
0.402 0.597 0.000
M48.9 Spondylopathy, unspecified
0.402 0.598 0.000
M48.8 Other specified spondylopathies
0.402 0.598 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.402 0.598 0.000
M48.4 Fatigue fracture of vertebra
0.402 0.598 0.000
M48.3 Traumatic spondylopathy
0.402 0.598 0.000
M48.2 Kissing spine
0.402 0.598 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.402 0.598 0.000
I44.1 Atrioventricular block, second degree
0.402 0.598 0.000
I44.6 Other and unspecified fascicular block
0.402 0.598 0.000
I44.5 Left posterior fascicular block
0.402 0.598 0.000
I44.4 Left anterior fascicular block
0.402 0.598 0.000
I44.3 Other and unspecified atrioventricular block
0.402 0.598 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.402 0.598 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.402 0.598 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.402 0.598 0.000
C21 Malignant neoplasm of anus and anal canal
0.402 0.598 0.000
C17 Malignant neoplasm of small intestine
0.402 0.598 0.000
C16 Malignant neoplasm of stomach
0.402 0.598 0.000
C23 Malignant neoplasm of gallbladder
0.402 0.598 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.402 0.598 0.000
H73 Other disorders of tympanic membrane
0.402 0.598 0.000
D86 Sarcoidosis
0.402 0.598 0.000
D75 Other diseases of blood and blood-forming organs
0.401 0.599 0.000
I61 Intracerebral haemorrhage
0.401 0.599 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.401 0.599 0.000
D09 Carcinoma in situ of other and unspecified sites
0.401 0.599 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.401 0.599 0.000
D06 Carcinoma in situ of cervix uteri
0.401 0.599 0.000
D04 Carcinoma in situ of skin
0.401 0.599 0.000
D03 Melanoma in situ
0.401 0.599 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.401 0.599 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.401 0.599 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.401 0.599 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.400 0.600 0.000
T79-T79 Certain early complications of trauma
0.400 0.600 0.000
T66-T78 Other and unspecified effects of external causes
0.400 0.600 0.000
T33-T35 Frostbite
0.400 0.600 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.400 0.600 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.400 0.600 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.400 0.600 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.400 0.600 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.400 0.600 0.000
T00-T07 Injuries involving multiple body regions
0.400 0.600 0.000
S90-S99 Injuries to the ankle and foot
0.400 0.600 0.000
S10-S19 Injuries to the neck
0.400 0.600 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.400 0.600 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.400 0.600 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.400 0.600 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.400 0.600 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.400 0.600 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.400 0.600 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.400 0.600 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.400 0.600 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.400 0.600 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.400 0.600 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.399 0.601 0.000
J44 Other chronic obstructive pulmonary disease
0.399 0.601 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.398 0.602 0.000
D60-D64 Aplastic and other anaemias
0.398 0.602 0.000
I77.1 Stricture of artery
0.397 0.602 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.396 0.604 0.000
I46.0 Cardiac arrest with successful resuscitation
0.396 0.604 0.000
D48.1 Connective and other soft tissue
0.396 0.604 0.000
M75.5 Bursitis of shoulder
0.396 0.604 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.395 0.604 0.000
Q80-Q89 Other congenital malformations
0.395 0.604 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.395 0.604 0.000
Q60-Q64 Congenital malformations of the urinary system
0.395 0.604 0.000
Q50-Q56 Congenital malformations of genital organs
0.395 0.604 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.395 0.604 0.000
Q35-Q37 Cleft lip and cleft palate
0.395 0.604 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.395 0.604 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.395 0.604 0.000
Q00-Q07 Congenital malformations of the nervous system
0.395 0.604 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.395 0.605 0.000
M84 Disorders of continuity of bone
0.394 0.606 0.000
M83 Adult osteomalacia
0.394 0.606 0.000
M82 Osteoporosis in diseases classified elsewhere
0.394 0.606 0.000
M80 Osteoporosis with pathological fracture
0.394 0.606 0.000
M54.2 Cervicalgia
0.394 0.606 0.000
M54.57 Low back pain (Lumbosacral region)
0.394 0.606 0.000
W20-W49 Exposure to inanimate mechanical forces
0.393 0.607 0.000
O36.8 Maternal care for other specified foetal problems
0.393 0.607 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.393 0.607 0.000
S40-S49 Injuries to the shoulder and upper arm
0.392 0.607 0.000
J69 Pneumonitis due to solids and liquids
0.392 0.608 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.392 0.608 0.000
D74 Methaemoglobinaemia
0.392 0.608 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.392 0.608 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.392 0.608 0.000
I73.8 Other specified peripheral vascular diseases
0.391 0.608 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.391 0.608 0.000
I49.9 Cardiac arrhythmia, unspecified
0.391 0.609 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.391 0.609 0.000
M16 Coxarthrosis [arthrosis of hip]
0.390 0.610 0.000
H66 Suppurative and unspecified otitis media
0.390 0.610 0.000
C18.7 Sigmoid colon
0.390 0.610 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.390 0.610 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.389 0.610 0.000
D24 Benign neoplasm of breast
0.389 0.611 0.000
D25 Leiomyoma of uterus
0.389 0.611 0.000
I25.5 Ischaemic cardiomyopathy
0.389 0.611 0.000
M99 Biomechanical lesions, not elsewhere classified
0.388 0.611 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.388 0.611 0.000
J03.9 Acute tonsillitis, unspecified
0.388 0.612 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.388 0.612 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.388 0.612 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.388 0.612 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.388 0.612 0.000
M75.8 Other shoulder lesions
0.388 0.612 0.000
M75.9 Shoulder lesion, unspecified
0.388 0.612 0.000
M75.2 Bicipital tendinitis
0.388 0.612 0.000
C91.1 Chronic lymphocytic leukaemia
0.387 0.613 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.387 0.613 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.387 0.613 0.000
C46 Kaposi's sarcoma
0.387 0.613 0.000
C45 Mesothelioma
0.387 0.613 0.000
D48.5 Skin
0.386 0.614 0.000
I46.9 Cardiac arrest, unspecified
0.385 0.614 0.000
I46.1 Sudden cardiac death, so described
0.385 0.614 0.000
C25 Malignant neoplasm of pancreas
0.385 0.615 0.000
C18.4 Transverse colon
0.385 0.615 0.000
M54.3 Sciatica
0.385 0.615 0.000
I51.8 Other ill-defined heart diseases
0.385 0.615 0.000
D10 Benign neoplasm of mouth and pharynx
0.385 0.615 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.384 0.616 0.000
H74 Other disorders of middle ear and mastoid
0.384 0.616 0.000
H70 Mastoiditis and related conditions
0.384 0.616 0.000
H69 Other disorders of Eustachian tube
0.384 0.616 0.000
H68 Eustachian salpingitis and obstruction
0.384 0.616 0.000
H67 Otitis media in diseases classified elsewhere
0.384 0.616 0.000
M18 Arthrosis of first carpometacarpal joint
0.384 0.616 0.000
D53 Other nutritional anaemias
0.383 0.616 0.000
D52 Folate deficiency anaemia
0.383 0.616 0.000
I10-I15 Hypertensive diseases
0.383 0.617 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.383 0.617 0.000
I35.9 Aortic valve disorder, unspecified
0.383 0.617 0.000
I35.8 Other aortic valve disorders
0.383 0.617 0.000
D51 Vitamin B12 deficiency anaemia
0.382 0.618 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.382 0.618 0.000
M54.55 Low back pain (Thoracolumbar region)
0.382 0.618 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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