TreeWAS – Variant ID: rs78788148

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.331	0.669
M20-M25 Other joint disorders	0.330	0.670
# Top node	0.330	0.670
M20 Acquired deformities of fingers and toes	0.328	0.672
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.318	0.682
Chapter VII Diseases of the eye and adnexa	0.315	0.685
M20.5 Other deformities of toe(s) (acquired)	0.309	0.691
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.303	0.697
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.294	0.705
M20.4 Other hammer toe(s) (acquired)	0.292	0.708
Chapter VIII Diseases of the ear and mastoid process	0.276	0.724
M20.1 Hallux valgus (acquired)	0.275	0.725
Chapter X Diseases of the respiratory system	0.269	0.731
Chapter XII Diseases of the skin and subcutaneous tissue	0.266	0.734
H40-H42 Glaucoma	0.266	0.734
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.264	0.736
H02 Other disorders of eyelid	0.263	0.737
Chapter II Neoplasms	0.263	0.737
R19 Other symptoms and signs involving the digestive system and abdomen	0.263	0.737
M20.2 Hallux rigidus	0.262	0.738
Chapter VI Diseases of the nervous system	0.260	0.740
M70-M79 Other soft tissue disorders	0.260	0.740
M23 Internal derangement of knee	0.259	0.741
M15-M19 Arthrosis	0.256	0.744
R47-R49 Symptoms and signs involving speech and voice	0.256	0.744
M65-M68 Disorders of synovium and tendon	0.255	0.745
H00 Hordeolum and chalazion	0.255	0.745
R14 Flatulence and related conditions	0.253	0.747
R13 Dysphagia	0.252	0.748
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.248	0.752
M35 Other systemic involvement of connective tissue	0.248	0.752
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.247	0.753
R50-R69 General symptoms and signs	0.245	0.755
M80-M85 Disorders of bone density and structure	0.244	0.756
M50-M54 Other dorsopathies	0.240	0.760
Chapter V Mental and behavioural disorders	0.240	0.760
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.238	0.762
M91-M94 Chondropathies	0.238	0.762
M86-M90 Other osteopathies	0.238	0.762
M60-M63 Disorders of muscles	0.238	0.762
M40-M43 Deforming dorsopathies	0.238	0.762
M00-M03 Infectious arthropathies	0.238	0.762
H90-H95 Other disorders of ear	0.238	0.762
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.237	0.763
M34 Systemic sclerosis	0.237	0.763
M33 Dermatopolymyositis	0.237	0.763
M32 Systemic lupus erythematosus	0.237	0.763
M31 Other necrotising vasculopathies	0.237	0.763
M30 Polyarteritis nodosa and related conditions	0.237	0.763
M25 Other joint disorders, not elsewhere classified	0.237	0.763
M24 Other specific joint derangements	0.237	0.763
M22 Disorders of patella	0.237	0.763
M21 Other acquired deformities of limbs	0.237	0.763
Chapter XXII Codes for special purposes	0.237	0.763
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.237	0.763
Chapter XVI Certain conditions originating in the perinatal period	0.237	0.763
Chapter I Certain infectious and parasitic diseases	0.236	0.764
Chapter XIV Diseases of the genitourinary system	0.236	0.764
M20.6 Acquired deformity of toe(s), unspecified	0.235	0.764
M20.3 Other deformity of hallux (acquired)	0.235	0.764
M20.0 Deformity of finger(s)	0.235	0.764
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.233	0.766
M45-M49 Spondylopathies	0.233	0.767
R11 Nausea and vomiting	0.233	0.767
M05-M14 Inflammatory polyarthropathies	0.232	0.768
H40 Glaucoma	0.230	0.770
Chapter XI Diseases of the digestive system	0.230	0.770
H25-H28 Disorders of lens	0.230	0.770
L60-L75 Disorders of skin appendages	0.228	0.772
R95-R99 Ill-defined and unknown causes of mortality	0.228	0.772
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.228	0.772
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.228	0.772
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.228	0.772
H02.8 Other specified disorders of eyelid	0.228	0.772
R18 Ascites	0.227	0.773
H00.1 Chalazion	0.226	0.773
H55-H59 Other disorders of eye and adnexa	0.226	0.774
H53-H54 Visual disturbances and blindness	0.226	0.774
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.226	0.774
H46-H48 Disorders of optic nerve and visual pathways	0.226	0.774
H43-H45 Disorders of vitreous body and globe	0.226	0.774
H30-H36 Disorders of choroid and retina	0.226	0.774
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.226	0.774
H10-H13 Disorders of conjunctiva	0.226	0.774
Chapter XV Pregnancy, childbirth and the puerperium	0.223	0.776
C50-C50 Malignant neoplasm of breast	0.221	0.778
Chapter IV Endocrine, nutritional and metabolic diseases	0.222	0.778
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.221	0.779
R10 Abdominal and pelvic pain	0.220	0.780
R19.4 Change in bowel habit	0.219	0.781
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.217	0.782
R17 Unspecified jaundice	0.217	0.782
R15 Faecal incontinence	0.217	0.782
J95-J99 Other diseases of the respiratory system	0.217	0.783
Chapter XX External causes of morbidity and mortality	0.217	0.783
H02.4 Ptosis of eyelid	0.216	0.784
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.214	0.786
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.213	0.787
S70-S79 Injuries to the hip and thigh	0.212	0.788
R69 Unknown and unspecified causes of morbidity	0.212	0.788
R47 Speech disturbances, not elsewhere classified	0.212	0.788
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.211	0.789
H05 Disorders of orbit	0.211	0.789
H04 Disorders of lachrymal system	0.211	0.789
H03 Disorders of eyelid in diseases classified elsewhere	0.211	0.789
H01 Other inflammation of eyelid	0.211	0.789
J30-J39 Other diseases of upper respiratory tract	0.210	0.790
H91 Other hearing loss	0.210	0.790
R12 Heartburn	0.210	0.790
J20-J22 Other acute lower respiratory infections	0.209	0.790
M75 Shoulder lesions	0.209	0.791
N80-N98 Noninflammatory disorders of female genital tract	0.208	0.792
M23.3 Other meniscus derangements	0.208	0.792
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.205	0.794
M16 Coxarthrosis [arthrosis of hip]	0.205	0.795
J40-J47 Chronic lower respiratory diseases	0.205	0.795
R20 Disturbances of skin sensation	0.202	0.798
G40-G47 Episodic and paroxysmal disorders	0.202	0.798
M65 Synovitis and tenosynovitis	0.200	0.799
L00-L08 Infections of the skin and subcutaneous tissue	0.199	0.801
H80-H83 Diseases of inner ear	0.198	0.802
H65-H75 Diseases of middle ear and mastoid	0.198	0.802
H60-H62 Diseases of external ear	0.198	0.802
H40.9 Glaucoma, unspecified	0.198	0.802
R91 Abnormal findings on diagnostic imaging of lung	0.197	0.803
S50-S59 Injuries to the elbow and forearm	0.196	0.804
C43-C44 Melanoma and other malignant neoplasms of skin	0.195	0.805
S00-S09 Injuries to the head	0.194	0.806
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.193	0.807
J80-J84 Other respiratory diseases principally affecting the interstitium	0.193	0.807
J60-J70 Lung diseases due to external agents	0.193	0.807
J00-J06 Acute upper respiratory infections	0.193	0.807
D00-D09 In situ neoplasms	0.193	0.807
G80-G83 Cerebral palsy and other paralytic syndromes	0.192	0.808
F40-F48 Neurotic, stress-related and somatoform disorders	0.192	0.808
C50 Malignant neoplasm of breast	0.192	0.808
L40-L45 Papulosquamous disorders	0.192	0.808
R50 Fever of unknown origin	0.191	0.809
L50-L54 Urticaria and erythema	0.191	0.809
L20-L30 Dermatitis and eczema	0.191	0.809
L10-L14 Bullous disorders	0.191	0.809
G50-G59 Nerve, nerve root and plexus disorders	0.191	0.809
H42 Glaucoma in diseases classified elsewhere	0.191	0.809
H91.9 Hearing loss, unspecified	0.190	0.809
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.190	0.810
T79-T79 Certain early complications of trauma	0.190	0.810
T66-T78 Other and unspecified effects of external causes	0.190	0.810
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.190	0.810
T36-T50 Poisoning by drugs, medicaments and biological substances	0.190	0.810
T33-T35 Frostbite	0.190	0.810
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.190	0.810
T26-T28 Burns and corrosions confined to eye and internal organs	0.190	0.810
T20-T25 Burns and corrosions of external body surface, specified by site	0.190	0.810
T15-T19 Effects of foreign body entering through natural orifice	0.190	0.810
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.190	0.810
T00-T07 Injuries involving multiple body regions	0.190	0.810
S90-S99 Injuries to the ankle and foot	0.190	0.810
S60-S69 Injuries to the wrist and hand	0.190	0.810
S40-S49 Injuries to the shoulder and upper arm	0.190	0.810
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.190	0.810
S20-S29 Injuries to the thorax	0.190	0.810
S10-S19 Injuries to the neck	0.190	0.810
L72 Follicular cysts of skin and subcutaneous tissue	0.190	0.810
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.189	0.811
M35.3 Polymyalgia rheumatica	0.189	0.811
H02.9 Disorder of eyelid, unspecified	0.189	0.811
H02.7 Other degenerative disorders of eyelid and periocular area	0.189	0.811
H02.6 Xanthelasma of eyelid	0.189	0.811
H02.5 Other disorders affecting eyelid function	0.189	0.811
H02.3 Blepharochalasis	0.189	0.811
H02.2 Lagophthalmos	0.189	0.811
H02.1 Ectropion of eyelid	0.189	0.811
H02.0 Entropion and trichiasis of eyelid	0.189	0.811
D37-D48 Neoplasms of uncertain or unknown behaviour	0.189	0.811
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.189	0.811
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.189	0.811
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.189	0.811
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.189	0.811
C51-C58 Malignant neoplasms of female genital organs	0.189	0.811
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.189	0.811
C40-C41 Malignant neoplasms of bone and articular cartilage	0.189	0.811
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.189	0.811
C15-C26 Malignant neoplasms of digestive organs	0.189	0.811
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.189	0.811
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.189	0.811
R19.6 Halitosis	0.189	0.811
R19.5 Other fecal abnormalities	0.189	0.811
R19.3 Abdominal rigidity	0.189	0.811
R19.2 Visible peristalsis	0.189	0.811
R19.1 Abnormal bowel sounds	0.189	0.811
N95 Menopausal and other perimenopausal disorders	0.188	0.812
B25-B34 Other viral diseases	0.188	0.812
C64-C68 Malignant neoplasms of urinary tract	0.187	0.813
M23.2 Derangement of meniscus due to old tear or injury	0.187	0.813
S80-S89 Injuries to the knee and lower leg	0.187	0.813
G90-G99 Other disorders of the nervous system	0.186	0.813
G70-G73 Diseases of myoneural junction and muscle	0.186	0.813
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.186	0.813
G35-G37 Demyelinating diseases of the central nervous system	0.186	0.813
G30-G32 Other degenerative diseases of the nervous system	0.186	0.813
G20-G26 Extrapyramidal and movement disorders	0.186	0.813
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.186	0.813
G00-G09 Inflammatory diseases of the central nervous system	0.186	0.813
M72 Fibroblastic disorders	0.186	0.813
M77 Other enthesopathies	0.186	0.814
M76 Enthesopathies of lower limb, excluding foot	0.186	0.814
M73 Soft tissue disorders in diseases classified elsewhere	0.186	0.814
M71 Other bursopathies	0.186	0.814
M70 Soft tissue disorders related to use, overuse and pressure	0.186	0.814
M54 Dorsalgia	0.186	0.814
M23.9 Internal derangement of knee, unspecified	0.186	0.814
M23.8 Other internal derangements of knee	0.186	0.814
M23.6 Other spontaneous disruption of ligament(s) of knee	0.186	0.814
M23.5 Chronic instability of knee	0.186	0.814
M23.4 Loose body in knee	0.186	0.814
M23.1 Discoid meniscus (congenital)	0.186	0.814
M23.0 Cystic meniscus	0.186	0.814
M79 Other soft tissue disorders, not elsewhere classified	0.185	0.814
M17 Gonarthrosis [arthrosis of knee]	0.185	0.815
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.185	0.815
R10.4 Other and unspecified abdominal pain	0.185	0.815
R53 Malaise and fatigue	0.184	0.816
M18 Arthrosis of first carpometacarpal joint	0.184	0.816
M15 Polyarthrosis	0.184	0.816
R49 Voice disturbances	0.184	0.816
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.184	0.816
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.184	0.816
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.183	0.817
M67 Other disorders of synovium and tendon	0.183	0.817
M66 Spontaneous rupture of synovium and tendon	0.183	0.817
D10-D36 Benign neoplasms	0.183	0.817
H00.0 Hordeolum and other deep inflammation of eyelid	0.183	0.817
R10.2 Pelvic and perineal pain	0.182	0.818
L60 Nail disorders	0.182	0.818
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.182	0.818
K50-K52 Noninfective enteritis and colitis	0.181	0.819
J90-J94 Other diseases of pleura	0.181	0.819
M81 Osteoporosis without pathological fracture	0.181	0.819
J98 Other respiratory disorders	0.180	0.820
R47.8 Other and unspecified speech disturbances	0.180	0.820
R30-R39 Symptoms and signs involving the urinary system	0.180	0.820
H40.0 Glaucoma suspect	0.180	0.820
H25 Senile cataract	0.179	0.820
C60-C63 Malignant neoplasms of male genital organs	0.179	0.821
N60-N64 Disorders of breast	0.179	0.821
R23 Other skin changes	0.178	0.822
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.178	0.822
R42 Dizziness and giddiness	0.178	0.822
A30-A49 Other bacterial diseases	0.178	0.822
M35.9 Systemic involvement of connective tissue, unspecified	0.178	0.822
M35.8 Other specified systemic involvement of connective tissue	0.178	0.822
M35.7 Hypermobility syndrome	0.178	0.822
M35.6 Relapsing panniculitis [Weber-Christian]	0.178	0.822
M35.5 Multifocal fibrosclerosis	0.178	0.822
M35.4 Diffuse (eosinophilic) fasciitis	0.178	0.822
M35.2 Behcet's disease	0.178	0.822
M35.1 Other overlap syndromes	0.178	0.822
M35.0 Sicca syndrome [Sjogren]	0.178	0.822
R94 Abnormal results of function studies	0.177	0.822
R93 Abnormal findings on diagnostic imaging of other body structures	0.177	0.822
R90 Abnormal findings on diagnostic imaging of central nervous system	0.177	0.822
R92 Abnormal findings on diagnostic imaging of breast	0.177	0.822
M19 Other arthrosis	0.177	0.823
K35-K38 Diseases of appendix	0.177	0.823
R68 Other general symptoms and signs	0.176	0.824
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.176	0.824
R62 Lack of expected normal physiological development	0.176	0.824
R61 Hyperhidrosis	0.176	0.824
R60 Oedema, not elsewhere classified	0.176	0.824
R57 Shock, not elsewhere classified	0.176	0.824
R56 Convulsions, not elsewhere classified	0.176	0.824
R52 Pain, not elsewhere classified	0.176	0.824
R64 Cachexia	0.176	0.824
R58 Haemorrhage, not elsewhere classified	0.176	0.824
R54 Senility	0.176	0.824
C50.4 Upper-outer quadrant of breast	0.175	0.825
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.175	0.825
M85 Other disorders of bone density and structure	0.175	0.825
M84 Disorders of continuity of bone	0.175	0.825
M83 Adult osteomalacia	0.175	0.825
M82 Osteoporosis in diseases classified elsewhere	0.175	0.825
M80 Osteoporosis with pathological fracture	0.175	0.825
S72 Fracture of femur	0.175	0.825
N40-N51 Diseases of male genital organs	0.174	0.826
L80-L99 Other disorders of the skin and subcutaneous tissue	0.174	0.826
R59 Enlarged lymph nodes	0.173	0.827
M53 Other dorsopathies, not elsewhere classified	0.172	0.827
M50 Cervical disk disorders	0.172	0.827
N70-N77 Inflammatory diseases of female pelvic organs	0.172	0.828
F99-F99 Unspecified mental disorder	0.172	0.828
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.172	0.828
F80-F89 Disorders of psychological development	0.172	0.828
F70-F79 Mental retardation	0.172	0.828
F60-F69 Disorders of adult personality and behaviour	0.172	0.828
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.172	0.828
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.172	0.828
F00-F09 Organic, including symptomatic, mental disorders	0.172	0.828
J33 Nasal polyp	0.172	0.828
K20-K31 Diseases of oesophagus, stomach and duodenum	0.172	0.828
R21 Rash and other nonspecific skin eruption	0.172	0.828
E50-E64 Other nutritional deficiencies	0.171	0.829
M06 Other rheumatoid arthritis	0.171	0.829
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.171	0.829
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.170	0.829
M02 Reactive arthropathies	0.170	0.829
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.170	0.829
M00 Pyogenic arthritis	0.170	0.829
M43 Other deforming dorsopathies	0.170	0.829
M42 Spinal osteochondrosis	0.170	0.829
M41 Scoliosis	0.170	0.829
M40 Kyphosis and lordosis	0.170	0.829
M63 Disorders of muscle in diseases classified elsewhere	0.170	0.829
M62 Other disorders of muscle	0.170	0.829
M61 Calcification and ossification of muscle	0.170	0.829
M60 Myositis	0.170	0.829
M90 Osteopathies in diseases classified elsewhere	0.170	0.829
M89 Other disorders of bone	0.170	0.829
M88 Paget's disease of bone [osteitis deformans]	0.170	0.829
M87 Osteonecrosis	0.170	0.829
M86 Osteomyelitis	0.170	0.829
M94 Other disorders of cartilage	0.170	0.829
M93 Other osteochondropathies	0.170	0.829
M92 Other juvenile osteochondrosis	0.170	0.829
M91 Juvenile osteochondrosis of hip and pelvis	0.170	0.829
M99 Biomechanical lesions, not elsewhere classified	0.170	0.829
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.170	0.829
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.170	0.829
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.170	0.829
H94 Other disorders of ear in diseases classified elsewhere	0.170	0.829
H93 Other disorders of ear, not elsewhere classified	0.170	0.829
H92 Otalgia and effusion of ear	0.170	0.829
H90 Conductive and sensorineural hearing loss	0.170	0.829
M21.9 Acquired deformity of limb, unspecified	0.170	0.830
M21.8 Other specified acquired deformities of limbs	0.170	0.830
M21.7 Unequal limb length (acquired)	0.170	0.830
M21.6 Other acquired deformities of ankle and foot	0.170	0.830
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.170	0.830
M21.4 Flat foot [pes planus] (acquired)	0.170	0.830
M21.3 Wrist or foot drop (acquired)	0.170	0.830
M21.2 Flexion deformity	0.170	0.830
M21.1 Varus deformity, not elsewhere classified	0.170	0.830
M21.0 Valgus deformity, not elsewhere classified	0.170	0.830
M22.1 Recurrent subluxation of patella	0.170	0.830
M22.9 Disorder of patella, unspecified	0.170	0.830
M22.8 Other disorders of patella	0.170	0.830
M22.4 Chondromalacia patellae	0.170	0.830
M22.3 Other derangements of patella	0.170	0.830
M22.2 Patellofemoral disorders	0.170	0.830
M22.0 Recurrent dislocation of patella	0.170	0.830
M24.9 Joint derangement, unspecified	0.170	0.830
M24.8 Other specific joint derangements, not elsewhere classified	0.170	0.830
M24.7 Protrusio acetabuli	0.170	0.830
M24.6 Ankylosis of joint	0.170	0.830
M24.5 Contracture of joint	0.170	0.830
M24.4 Recurrent dislocation and subluxation of joint	0.170	0.830
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.170	0.830
M24.2 Disorder of ligament	0.170	0.830
M24.1 Other articular cartilage disorders	0.170	0.830
M24.0 Loose body in joint	0.170	0.830
M25.9 Joint disorder, unspecified	0.170	0.830
M25.8 Other specified joint disorders	0.170	0.830
M25.7 Osteophyte	0.170	0.830
M25.6 Stiffness of joint, not elsewhere classified	0.170	0.830
M25.5 Pain in joint	0.170	0.830
M25.4 Effusion of joint	0.170	0.830
M25.3 Other instability of joint	0.170	0.830
M25.2 Flail joint	0.170	0.830
M25.1 Fistula of joint	0.170	0.830
M25.0 Haemarthrosis	0.170	0.830
M30.8 Other conditions related to polyarteritis nodosa	0.170	0.830
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.170	0.830
M30.2 Juvenile polyarteritis	0.170	0.830
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.170	0.830
M30.0 Polyarteritis nodosa	0.170	0.830
M31.9 Necrotising vasculopathy, unspecified	0.170	0.830
M31.8 Other specified necrotising vasculopathies	0.170	0.830
M31.7 Microscopic polyangiitis	0.170	0.830
M31.6 Other giant cell arteritis	0.170	0.830
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.170	0.830
M31.4 Aortic arch syndrome [Takayasu]	0.170	0.830
M31.3 Wegener's granulomatosis	0.170	0.830
M31.2 Lethal midline granuloma	0.170	0.830
M31.1 Thrombotic microangiopathy	0.170	0.830
M31.0 Hypersensitivity angiitis	0.170	0.830
M32.9 Systemic lupus erythematosus, unspecified	0.170	0.830
M32.8 Other forms of systemic lupus erythematosus	0.170	0.830
M32.1 Systemic lupus erythematosus with organ or system involvement	0.170	0.830
M32.0 Drug-induced systemic lupus erythematosus	0.170	0.830
M33.9 Dermatopolymyositis, unspecified	0.170	0.830
M33.2 Polymyositis	0.170	0.830
M33.1 Other dermatomyositis	0.170	0.830
M33.0 Juvenile dermatomyositis	0.170	0.830
M34.9 Systemic sclerosis, unspecified	0.170	0.830
M34.8 Other forms of systemic sclerosis	0.170	0.830
M34.2 Systemic sclerosis induced by drugs and chemicals	0.170	0.830
M34.1 CR(E)ST syndrome	0.170	0.830
M34.0 Progressive systemic sclerosis	0.170	0.830
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.170	0.830
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.170	0.830
M36.3 Arthropathy in other blood disorders	0.170	0.830
M36.2 Haemophilic arthropathy	0.170	0.830
M36.1 Arthropathy in neoplastic disease	0.170	0.830
M36.0 Dermato(poly)myositis in neoplastic disease	0.170	0.830
P90-P96 Other disorders originating in the perinatal period	0.170	0.830
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.170	0.830
P75-P78 Digestive system disorders of fetus and newborn	0.170	0.830
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.170	0.830
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.170	0.830
P35-P39 Infections specific to the perinatal period	0.170	0.830
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.170	0.830
P10-P15 Birth trauma	0.170	0.830
P05-P08 Disorders related to length of gestation and fetal growth	0.170	0.830
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.170	0.830
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.170	0.830
Q80-Q89 Other congenital malformations	0.170	0.830
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.170	0.830
Q60-Q64 Congenital malformations of the urinary system	0.170	0.830
Q50-Q56 Congenital malformations of genital organs	0.170	0.830
Q38-Q45 Other congenital malformations of the digestive system	0.170	0.830
Q35-Q37 Cleft lip and cleft palate	0.170	0.830
Q30-Q34 Congenital malformations of the respiratory system	0.170	0.830
Q20-Q28 Congenital malformations of the circulatory system	0.170	0.830
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.170	0.830
Q00-Q07 Congenital malformations of the nervous system	0.170	0.830
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.170	0.830
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.170	0.830
R20.8 Other and unspecified disturbances of skin sensation	0.169	0.830
B99-B99 Other infectious diseases	0.169	0.831
B90-B94 Sequelae of infectious and parasitic diseases	0.169	0.831
B85-B89 Pediculosis, acariasis and other infestations	0.169	0.831
B65-B83 Helminthiases	0.169	0.831
B50-B64 Protozoal diseases	0.169	0.831
B35-B49 Mycoses	0.169	0.831
B20-B24 Human immunodeficiency virus [HIV] disease	0.169	0.831
B15-B19 Viral hepatitis	0.169	0.831
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.169	0.831
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.169	0.831
A80-A89 Viral infections of the central nervous system	0.169	0.831
A75-A79 Rickettsioses	0.169	0.831
A70-A74 Other diseases caused by chlamydiae	0.169	0.831
A65-A69 Other spirochaetal diseases	0.169	0.831
A50-A64 Infections with a predominantly sexual mode of transmission	0.169	0.831
A20-A28 Certain zoonotic bacterial diseases	0.169	0.831
A15-A19 Tuberculosis	0.169	0.831
N99-N99 Other disorders of the genitourinary system	0.169	0.831
N25-N29 Other disorders of kidney and ureter	0.169	0.831
N10-N16 Renal tubulo-interstitial diseases	0.169	0.831
N00-N08 Glomerular diseases	0.169	0.831
M16.1 Other primary coxarthrosis	0.169	0.831
O80-O84 Delivery	0.169	0.831
N95.0 Postmenopausal bleeding	0.169	0.831
M75.1 Rotator cuff syndrome	0.168	0.832
R06 Abnormalities of breathing	0.168	0.832
R46 Symptoms and signs involving appearance and behaviour	0.167	0.832
R45 Symptoms and signs involving emotional state	0.167	0.832
R44 Other symptoms and signs involving general sensations and perceptions	0.167	0.832
R43 Disturbances of smell and taste	0.167	0.832
R40 Somnolence, stupor and coma	0.167	0.832
M49 Spondylopathies in diseases classified elsewhere	0.167	0.832
M47 Spondylosis	0.167	0.832
M46 Other inflammatory spondylopathies	0.167	0.832
M45 Ankylosing spondylitis	0.167	0.832
K90-K93 Other diseases of the digestive system	0.167	0.833
M14 Arthropathies in other diseases classified elsewhere	0.167	0.833
M12 Other specific arthropathies	0.167	0.833
M11 Other crystal arthropathies	0.167	0.833
M10 Gout	0.167	0.833
M09 Juvenile arthritis in diseases classified elsewhere	0.167	0.833
M08 Juvenile arthritis	0.167	0.833
M07 Psoriatic and enteropathic arthropathies	0.167	0.833
M05 Seropositive rheumatoid arthritis	0.167	0.833
J22 Unspecified acute lower respiratory infection	0.167	0.833
R51 Headache	0.166	0.834
G47 Sleep disorders	0.165	0.835
H40.8 Other glaucoma	0.165	0.835
H40.6 Glaucoma secondary to drugs	0.165	0.835
H40.5 Glaucoma secondary to other eye disorders	0.165	0.835
H40.4 Glaucoma secondary to eye inflammation	0.165	0.835
H40.3 Glaucoma secondary to eye trauma	0.165	0.835
H40.2 Primary angle-closure glaucoma	0.165	0.835
H40.1 Primary open-angle glaucoma	0.165	0.835
K70-K77 Diseases of liver	0.165	0.835
K65-K67 Diseases of peritoneum	0.165	0.835
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.165	0.835
H27 Other disorders of lens	0.165	0.835
R04 Haemorrhage from respiratory passages	0.165	0.835
E70-E90 Metabolic disorders	0.165	0.835
F30-F39 Mood [affective] disorders	0.165	0.835
N85 Other noninflammatory disorders of uterus, except cervix	0.165	0.835
L75 Apocrine sweat disorders	0.164	0.836
L74 Eccrine sweat disorders	0.164	0.836
L73 Other follicular disorders	0.164	0.836
L71 Rosacea	0.164	0.836
L70 Acne	0.164	0.836
L68 Hypertrichosis	0.164	0.836
L67 Hair colour and hair shaft abnormalities	0.164	0.836
L66 Cicatricial alopecia [scarring hair loss]	0.164	0.836
L65 Other nonscarring hair loss	0.164	0.836
L64 Androgenic alopecia	0.164	0.836
L63 Alopecia areata	0.164	0.836

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations