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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79144467
log Bayes Factor = 15.3649
Chromosome 4   position 176,504,741  (GRCh37) Explore rs79144467 on Ensembl!
Variant rs79144467 is part of Cluster X0051

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
E78.0 Pure hypercholesterolaemia
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.994 0.006 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.992 0.008 0.000
Chapter V Mental and behavioural disorders
0.988 0.012 0.000
Z72 Problems related to lifestyle
0.982 0.018 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.981 0.019 0.000
Chapter II Neoplasms
0.981 0.019 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.981 0.019 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.977 0.023 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.977 0.023 0.000
I44 Atrioventricular and left bundle-branch block
0.971 0.029 0.000
Z72.0 Tobacco use
0.970 0.030 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.964 0.036 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.963 0.037 0.000
I20 Angina pectoris
0.961 0.039 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.959 0.041 0.000
Z13 Special screening examination for other diseases and disorders
0.959 0.041 0.000
I47 Paroxysmal tachycardia
0.959 0.041 0.000
I25 Chronic ischaemic heart disease
0.957 0.043 0.000
Z13.9 Special screening examination, unspecified
0.957 0.043 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.956 0.044 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.954 0.046 0.000
A30-A49 Other bacterial diseases
0.944 0.055 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.943 0.057 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.942 0.058 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.939 0.061 0.000
Z96 Presence of other functional implants
0.938 0.062 0.000
I47.1 Supraventricular tachycardia
0.937 0.063 0.000
I44.0 Atrioventricular block, first degree
0.934 0.066 0.000
I20.9 Angina pectoris, unspecified
0.930 0.070 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.930 0.070 0.000
I25.1 Atherosclerotic heart disease
0.929 0.071 0.000
I10-I15 Hypertensive diseases
0.928 0.072 0.000
E65-E68 Obesity and other hyperalimentation
0.926 0.074 0.000
Z96.0 Presence of urogenital implants
0.923 0.077 0.000
M20-M25 Other joint disorders
0.921 0.079 0.000
I49 Other cardiac arrhythmias
0.915 0.085 0.000
E78.5 Hyperlipidaemia, unspecified
0.906 0.094 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.902 0.098 0.000
A41 Other septicaemia
0.899 0.101 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.896 0.104 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.894 0.106 0.000
E87.2 Acidosis
0.893 0.107 0.000
M70-M79 Other soft tissue disorders
0.892 0.108 0.000
C15-C26 Malignant neoplasms of digestive organs
0.880 0.120 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.879 0.121 0.000
E66 Obesity
0.874 0.126 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.874 0.126 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.873 0.127 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.866 0.134 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.866 0.134 0.000
I10 Essential (primary) hypertension
0.864 0.136 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.863 0.137 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.862 0.138 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.860 0.140 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.855 0.145 0.000
I22 Subsequent myocardial infarction
0.854 0.146 0.000
C83.3 Large cell (diffuse)
0.853 0.147 0.000
I49.9 Cardiac arrhythmia, unspecified
0.848 0.152 0.000
E87.6 Hypokalaemia
0.848 0.152 0.000
E66.9 Obesity, unspecified
0.847 0.153 0.000
I31 Other diseases of pericardium
0.844 0.156 0.000
A41.9 Septicaemia, unspecified
0.833 0.167 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.830 0.170 0.000
Z95.2 Presence of prosthetic heart valve
0.830 0.170 0.000
Z86 Personal history of certain other diseases
0.824 0.176 0.000
Z74 Problems related to care-provider dependency
0.823 0.177 0.000
I44.2 Atrioventricular block, complete
0.822 0.178 0.000
Chapter XX External causes of morbidity and mortality
0.821 0.179 0.000
Z95.4 Presence of other heart-valve replacement
0.819 0.181 0.000
I51 Complications and ill-defined descriptions of heart disease
0.816 0.184 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.815 0.185 0.000
Z72.1 Alcohol use
0.815 0.185 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.815 0.185 0.000
S60-S69 Injuries to the wrist and hand
0.814 0.186 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.814 0.186 0.000
E20-E35 Disorders of other endocrine glands
0.811 0.189 0.000
S80-S89 Injuries to the knee and lower leg
0.809 0.191 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.808 0.192 0.000
I20.8 Other forms of angina pectoris
0.806 0.194 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.806 0.194 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.806 0.194 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.805 0.195 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.805 0.195 0.000
Z97 Presence of other devices
0.805 0.195 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.804 0.196 0.000
M21 Other acquired deformities of limbs
0.803 0.197 0.000
S00-S09 Injuries to the head
0.801 0.199 0.000
E87.0 Hyperosmolality and hypernatraemia
0.799 0.201 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.799 0.201 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.790 0.210 0.000
M05-M14 Inflammatory polyarthropathies
0.785 0.215 0.000
C92 Myeloid leukaemia
0.784 0.216 0.000
I35 Nonrheumatic aortic valve disorders
0.784 0.216 0.000
Z93 Artificial opening status
0.783 0.217 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.781 0.219 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.777 0.223 0.000
S40-S49 Injuries to the shoulder and upper arm
0.777 0.223 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.776 0.224 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.774 0.226 0.000
E83 Disorders of mineral metabolism
0.770 0.230 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.769 0.231 0.000
M75 Shoulder lesions
0.767 0.233 0.000
M25 Other joint disorders, not elsewhere classified
0.765 0.235 0.000
M20 Acquired deformities of fingers and toes
0.764 0.236 0.000
Z92 Personal history of medical treatment
0.764 0.236 0.000
S50-S59 Injuries to the elbow and forearm
0.764 0.236 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.763 0.237 0.000
I44.7 Left bundle-branch block, unspecified
0.758 0.242 0.000
Chapter XXII Codes for special purposes
0.757 0.243 0.000
Z86.4 Personal history of psychoactive substance abuse
0.757 0.243 0.000
Z96.2 Presence of otological and audiological implants
0.757 0.243 0.000
Z89 Acquired absence of limb
0.755 0.245 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.754 0.246 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.752 0.248 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.752 0.248 0.000
I34 Nonrheumatic mitral valve disorders
0.752 0.248 0.000
I33 Acute and subacute endocarditis
0.751 0.249 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.748 0.252 0.000
F60-F69 Disorders of adult personality and behaviour
0.747 0.253 0.000
Z90.7 Acquired absence of genital organ(s)
0.746 0.254 0.000
C18 Malignant neoplasm of colon
0.744 0.256 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.743 0.257 0.000
Chapter XI Diseases of the digestive system
0.743 0.257 0.000
E87.7 Fluid overload
0.742 0.258 0.000
I05-I09 Chronic rheumatic heart diseases
0.742 0.258 0.000
I31.3 Pericardial effusion (noninflammatory)
0.737 0.263 0.000
Z90.2 Acquired absence of lung [part of]
0.736 0.264 0.000
M31 Other necrotising vasculopathies
0.736 0.264 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.735 0.265 0.000
Chapter VII Diseases of the eye and adnexa
0.735 0.265 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.734 0.266 0.000
M00-M03 Infectious arthropathies
0.734 0.266 0.000
Z82.3 Family history of stroke
0.733 0.267 0.000
M24 Other specific joint derangements
0.732 0.268 0.000
C78.0 Secondary malignant neoplasm of lung
0.730 0.270 0.000
S62 Fracture at wrist and hand level
0.727 0.273 0.000
F80-F89 Disorders of psychological development
0.726 0.274 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.726 0.274 0.000
C64-C68 Malignant neoplasms of urinary tract
0.726 0.274 0.000
I24 Other acute ischaemic heart diseases
0.725 0.275 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.724 0.276 0.000
Z75 Problems related to medical facilities and other health care
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.722 0.278 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.722 0.278 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.721 0.279 0.000
S70-S79 Injuries to the hip and thigh
0.721 0.279 0.000
K35-K38 Diseases of appendix
0.721 0.279 0.000
F40 Phobic anxiety disorders
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.719 0.281 0.000
Z96.7 Presence of other bone and tendon implants
0.718 0.282 0.000
M79.6 Pain in limb
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E88 Other metabolic disorders
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
E78.8 Other disorders of lipoprotein metabolism
0.717 0.283 0.000
E78.6 Lipoprotein deficiency
0.717 0.283 0.000
E78.4 Other hyperlipidaemia
0.717 0.283 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
E78.2 Mixed hyperlipidaemia
0.717 0.283 0.000
E78.1 Pure hyperglyceridaemia
0.717 0.283 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.716 0.284 0.000
Chapter VI Diseases of the nervous system
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.715 0.285 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.714 0.286 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.714 0.286 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.714 0.286 0.000
Chapter VIII Diseases of the ear and mastoid process
0.713 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.713 0.287 0.000
F99-F99 Unspecified mental disorder
0.712 0.287 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
S10-S19 Injuries to the neck
0.712 0.288 0.000
Z76 Persons encountering health services in other circumstances
0.711 0.289 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.711 0.289 0.000
C85.1 B-cell lymphoma, unspecified
0.711 0.289 0.000
T81 Complications of procedures, not elsewhere classified
0.711 0.289 0.000
A49 Bacterial infection of unspecified site
0.710 0.290 0.000
Z95.3 Presence of xenogenic heart valve
0.709 0.291 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
B15-B19 Viral hepatitis
0.708 0.292 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.292 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.708 0.292 0.000
Z73 Problems related to life-management difficulty
0.706 0.294 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.706 0.294 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.705 0.295 0.000
M86-M90 Other osteopathies
0.704 0.296 0.000
Z72.9 Problem related to lifestyle, unspecified
0.704 0.296 0.000
Z72.8 Other problems related to lifestyle
0.704 0.296 0.000
Z72.6 Gambling and betting
0.704 0.296 0.000
Z72.5 High-risk sexual behaviour
0.704 0.296 0.000
Z72.4 Inappropriate diet and eating habits
0.704 0.296 0.000
Z72.3 Lack of physical exercise
0.704 0.296 0.000
Z72.2 Drug use
0.704 0.296 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.703 0.296 0.000
E87.4 Mixed disorder of acid-base balance
0.703 0.296 0.000
E87.3 Alkalosis
0.703 0.296 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.703 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.703 0.296 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.703 0.296 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.703 0.297 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.703 0.297 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.703 0.297 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.703 0.297 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.703 0.297 0.000
I11 Hypertensive heart disease
0.703 0.297 0.000
F10.2 Dependence syndrome
0.702 0.298 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.700 0.300 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.700 0.300 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.700 0.300 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.700 0.300 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.700 0.300 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.700 0.300 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.700 0.300 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.700 0.300 0.000
Z82.2 Family history of deafness and hearing loss
0.700 0.300 0.000
Z82.1 Family history of blindness and visual loss
0.700 0.300 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.700 0.300 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.700 0.300 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.698 0.302 0.000
M65-M68 Disorders of synovium and tendon
0.697 0.303 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.696 0.304 0.000
I44.6 Other and unspecified fascicular block
0.696 0.304 0.000
I44.5 Left posterior fascicular block
0.696 0.304 0.000
I44.4 Left anterior fascicular block
0.696 0.304 0.000
I44.3 Other and unspecified atrioventricular block
0.696 0.304 0.000
E87.5 Hyperkalaemia
0.695 0.305 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.694 0.306 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.694 0.306 0.000
Z02 Examination and encounter for administrative purposes
0.693 0.307 0.000
M22 Disorders of patella
0.692 0.308 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.692 0.308 0.000
C78.7 Secondary malignant neoplasm of liver
0.691 0.309 0.000
M91-M94 Chondropathies
0.691 0.309 0.000
M60-M63 Disorders of muscles
0.691 0.309 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.691 0.309 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.691 0.309 0.000
Z86.7 Personal history of diseases of the circulatory system
0.690 0.310 0.000
D00-D09 In situ neoplasms
0.690 0.310 0.000
C25 Malignant neoplasm of pancreas
0.689 0.311 0.000
I20.1 Angina pectoris with documented spasm
0.689 0.311 0.000
K35 Acute appendicitis
0.688 0.312 0.000
M06 Other rheumatoid arthritis
0.688 0.312 0.000
Z10 Routine general health check-up of defined subpopulation
0.688 0.312 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.688 0.312 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.688 0.312 0.000
Z13.5 Special screening examination for eye and ear disorders
0.688 0.312 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.688 0.312 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.688 0.312 0.000
Z13.2 Special screening examination for nutritional disorders
0.688 0.312 0.000
Z13.1 Special screening examination for diabetes mellitus
0.688 0.312 0.000
F41 Other anxiety disorders
0.687 0.313 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.687 0.313 0.000
I47.0 Reentry ventricular arrhythmia
0.687 0.313 0.000
C18.7 Sigmoid colon
0.687 0.313 0.000
Z98 Other postsurgical states
0.686 0.314 0.000
I25.6 Silent myocardial ischaemia
0.686 0.314 0.000
I25.5 Ischaemic cardiomyopathy
0.686 0.314 0.000
I25.4 Coronary artery aneurysm
0.686 0.314 0.000
I25.3 Aneurysm of heart
0.686 0.314 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.686 0.314 0.000
I51.7 Cardiomegaly
0.686 0.314 0.000
C16 Malignant neoplasm of stomach
0.686 0.314 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.685 0.315 0.000
C95 Leukaemia of unspecified cell type
0.685 0.315 0.000
C94 Other leukaemias of specified cell type
0.685 0.315 0.000
C93 Monocytic leukaemia
0.685 0.315 0.000
C88 Malignant immunoproliferative diseases
0.685 0.315 0.000
C86 Other specified types of T/NK-cell lymphoma
0.685 0.315 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.685 0.315 0.000
C81 Hodgkin's disease
0.685 0.315 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.685 0.315 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.684 0.316 0.000
I49.3 Ventricular premature depolarisation
0.683 0.317 0.000
S80 Superficial injury of lower leg
0.683 0.317 0.000
Z04 Examination and observation for other reasons
0.683 0.317 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.682 0.318 0.000
I95 Hypotension
0.682 0.318 0.000
B25-B34 Other viral diseases
0.681 0.319 0.000
I60-I69 Cerebrovascular diseases
0.681 0.319 0.000
M50-M54 Other dorsopathies
0.680 0.320 0.000
T82.1 Mechanical complication of cardiac electronic device
0.680 0.320 0.000
I45 Other conduction disorders
0.679 0.321 0.000
A48 Other bacterial diseases, not elsewhere classified
0.677 0.323 0.000
A44 Bartonellosis
0.677 0.323 0.000
A43 Nocardiosis
0.677 0.323 0.000
A42 Actinomycosis
0.677 0.323 0.000
A40 Streptococcal septicaemia
0.677 0.323 0.000
A39 Meningococcal infection
0.677 0.323 0.000
A37 Whooping cough
0.677 0.323 0.000
A36 Diphtheria
0.677 0.323 0.000
A32 Listeriosis
0.677 0.323 0.000
A31 Infection due to other mycobacteria
0.677 0.323 0.000
A30 Leprosy [Hansen's disease]
0.677 0.323 0.000
A46 Erysipelas
0.677 0.323 0.000
A38 Scarlet fever
0.677 0.323 0.000
A35 Other tetanus
0.677 0.323 0.000
A34 Obstetrical tetanus
0.677 0.323 0.000
A33 Tetanus neonatorum
0.677 0.323 0.000
F10.0 Acute intoxication
0.677 0.323 0.000
I12 Hypertensive renal disease
0.676 0.324 0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters
0.676 0.324 0.000
T87 Complications peculiar to reattachment and amputation
0.675 0.325 0.000
T86 Failure and rejection of transplanted organs and tissues
0.675 0.325 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.675 0.325 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
I80 Phlebitis and thrombophlebitis
0.674 0.326 0.000
Z85 Personal history of malignant neoplasm
0.674 0.326 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.673 0.327 0.000
Z96.9 Presence of functional implant, unspecified
0.673 0.327 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.673 0.327 0.000
Z96.4 Presence of endocrine implants
0.673 0.327 0.000
Z96.3 Presence of artificial larynx
0.673 0.327 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.672 0.327 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.672 0.328 0.000
K70-K77 Diseases of liver
0.671 0.329 0.000
M80-M85 Disorders of bone density and structure
0.671 0.329 0.000
T93 Sequelae of injuries of lower limb
0.670 0.330 0.000
F01 Vascular dementia
0.670 0.330 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.670 0.330 0.000
I49.8 Other specified cardiac arrhythmias
0.669 0.331 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.668 0.332 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.668 0.332 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.666 0.334 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.665 0.335 0.000
I15 Secondary hypertension
0.665 0.335 0.000
I13 Hypertensive heart and renal disease
0.665 0.335 0.000
C80 Malignant neoplasm without specification of site
0.665 0.335 0.000
E67 Other hyperalimentation
0.664 0.336 0.000
E68 Sequelae of hyperalimentation
0.664 0.336 0.000
E65 Localised adiposity
0.664 0.336 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.664 0.336 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.663 0.337 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.662 0.338 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.661 0.339 0.000
M34 Systemic sclerosis
0.661 0.339 0.000
M33 Dermatopolymyositis
0.661 0.339 0.000
M32 Systemic lupus erythematosus
0.661 0.339 0.000
M30 Polyarteritis nodosa and related conditions
0.661 0.339 0.000
Z94 Transplanted organ and tissue status
0.660 0.340 0.000
Z90.0 Acquired absence of part of head and neck
0.659 0.341 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.658 0.342 0.000
C60-C63 Malignant neoplasms of male genital organs
0.658 0.342 0.000
Z12 Special screening examination for neoplasms
0.657 0.343 0.000
M20.0 Deformity of finger(s)
0.657 0.343 0.000
I38 Endocarditis, valve unspecified
0.656 0.343 0.000
S64 Injury of nerves at wrist and hand level
0.656 0.344 0.000
I49.4 Other and unspecified premature depolarisation
0.656 0.344 0.000
I49.2 Junctional premature depolarisation
0.656 0.344 0.000
I49.1 Atrial premature depolarisation
0.656 0.344 0.000
M35 Other systemic involvement of connective tissue
0.656 0.344 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.656 0.344 0.000
F50 Eating disorders
0.655 0.345 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.655 0.345 0.000
C51-C58 Malignant neoplasms of female genital organs
0.654 0.346 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.654 0.346 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.654 0.346 0.000
I49.0 Ventricular fibrillation and flutter
0.653 0.347 0.000
E83.5 Disorders of calcium metabolism
0.653 0.347 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.653 0.347 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.652 0.347 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.652 0.348 0.000
M40-M43 Deforming dorsopathies
0.652 0.348 0.000
F20 Schizophrenia
0.652 0.348 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.651 0.349 0.000
E10-E14 Diabetes mellitus
0.649 0.351 0.000
W20-W49 Exposure to inanimate mechanical forces
0.649 0.351 0.000
I49.5 Sick sinus syndrome
0.649 0.351 0.000
K11 Diseases of salivary glands
0.648 0.352 0.000
M21.4 Flat foot [pes planus] (acquired)
0.646 0.353 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.646 0.354 0.000
S01 Open wound of head
0.646 0.354 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.646 0.354 0.000
F43 Reaction to severe stress, and adjustment disorders
0.645 0.355 0.000
A41.8 Other specified septicaemia
0.645 0.355 0.000
A41.4 Septicaemia due to anaerobes
0.645 0.355 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.645 0.355 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.645 0.355 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.645 0.355 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.645 0.355 0.000
C20 Malignant neoplasm of rectum
0.645 0.355 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.644 0.356 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.644 0.356 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.644 0.356 0.000
Z90.3 Acquired absence of part of stomach
0.644 0.356 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.642 0.358 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.642 0.358 0.000
C83.7 Burkitt's tumour
0.642 0.358 0.000
C83.6 Undifferentiated (diffuse)
0.642 0.358 0.000
C83.5 Lymphoblastic (diffuse)
0.642 0.358 0.000
C83.4 Immunoblastic (diffuse)
0.642 0.358 0.000
C83.2 Mixed small and large cell (diffuse)
0.642 0.358 0.000
C83.1 Small cleaved cell (diffuse)
0.642 0.358 0.000
C83.0 Small cell (diffuse)
0.642 0.358 0.000
H53-H54 Visual disturbances and blindness
0.642 0.358 0.000
I46 Cardiac arrest
0.641 0.359 0.000
F05.9 Delirium, unspecified
0.641 0.359 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.641 0.359 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.641 0.359 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.641 0.359 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.641 0.359 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.641 0.359 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.641 0.359 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.641 0.359 0.000
F11 Mental and behavioural disorders due to use of opioids
0.641 0.359 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.640 0.360 0.000
F45 Somatoform disorders
0.640 0.360 0.000
F10.3 Withdrawal state
0.640 0.360 0.000
Z80 Family history of malignant neoplasm
0.640 0.360 0.000
M76 Enthesopathies of lower limb, excluding foot
0.639 0.361 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.639 0.361 0.000
M71 Other bursopathies
0.639 0.361 0.000
Chapter XIV Diseases of the genitourinary system
0.639 0.361 0.000
F03 Unspecified dementia
0.638 0.362 0.000
Chapter X Diseases of the respiratory system
0.637 0.363 0.000
F22 Persistent delusional disorders
0.637 0.363 0.000
E23 Hypofunction and other disorders of pituitary gland
0.634 0.366 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.633 0.367 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.633 0.367 0.000
S62.6 Fracture of other finger
0.632 0.368 0.000
C71 Malignant neoplasm of brain
0.632 0.368 0.000
C78.2 Secondary malignant neoplasm of pleura
0.631 0.369 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.631 0.369 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.631 0.369 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.631 0.369 0.000
C21 Malignant neoplasm of anus and anal canal
0.631 0.369 0.000
C17 Malignant neoplasm of small intestine
0.631 0.369 0.000
C23 Malignant neoplasm of gallbladder
0.631 0.369 0.000
M75.5 Bursitis of shoulder
0.630 0.370 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.629 0.371 0.000
M79.67 Pain in limb (Ankle and foot)
0.628 0.372 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.628 0.372 0.000
Z90.5 Acquired absence of kidney
0.628 0.372 0.000
M75.3 Calcific tendinitis of shoulder
0.628 0.372 0.000
M77 Other enthesopathies
0.627 0.373 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.627 0.373 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.627 0.373 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.626 0.373 0.000
E66.1 Drug-induced obesity
0.626 0.373 0.000
E66.0 Obesity due to excess calories
0.626 0.373 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.626 0.374 0.000
E50-E64 Other nutritional deficiencies
0.625 0.374 0.000
S40 Superficial injury of shoulder and upper arm
0.625 0.375 0.000
M75.0 Adhesive capsulitis of shoulder
0.625 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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