TreeWAS – Variant ID: rs79169085

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
Chapter VI Diseases of the nervous system	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
Chapter II Neoplasms	0.995	0.005
C60-C63 Malignant neoplasms of male genital organs	0.988	0.012
O60-O75 Complications of labour and delivery	0.985	0.015
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.984	0.016
C61 Malignant neoplasm of prostate	0.984	0.016
G80-G83 Cerebral palsy and other paralytic syndromes	0.980	0.020
Chapter XI Diseases of the digestive system	0.979	0.021
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.976	0.024
K80.2 Calculus of gallbladder without cholecystitis	0.972	0.028
K80 Cholelithiasis	0.972	0.028
Chapter XII Diseases of the skin and subcutaneous tissue	0.964	0.036
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.962	0.038
Chapter XX External causes of morbidity and mortality	0.962	0.038
S80-S89 Injuries to the knee and lower leg	0.962	0.038
L80-L99 Other disorders of the skin and subcutaneous tissue	0.960	0.040
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.958	0.042
M70-M79 Other soft tissue disorders	0.955	0.045
G81 Hemiplegia	0.951	0.049
O63 Long labour	0.943	0.057
M65-M68 Disorders of synovium and tendon	0.943	0.057
G40-G47 Episodic and paroxysmal disorders	0.935	0.065
L97 Ulcer of lower limb, not elsewhere classified	0.932	0.068
G81.9 Hemiplegia, unspecified	0.929	0.071
G20-G26 Extrapyramidal and movement disorders	0.927	0.073
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.917	0.083
S00-S09 Injuries to the head	0.913	0.087
M20-M25 Other joint disorders	0.908	0.092
C77.2 Intra-abdominal lymph nodes	0.903	0.097
K90-K93 Other diseases of the digestive system	0.899	0.101
O20-O29 Other maternal disorders predominantly related to pregnancy	0.899	0.101
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.889	0.111
M79 Other soft tissue disorders, not elsewhere classified	0.887	0.113
O63.0 Prolonged first stage (of labour)	0.881	0.119
M23 Internal derangement of knee	0.879	0.121
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.873	0.127
O68 Labour and delivery complicated by foetal stress [distress]	0.872	0.128
S70-S79 Injuries to the hip and thigh	0.869	0.131
C15-C26 Malignant neoplasms of digestive organs	0.869	0.131
L90 Atrophic disorders of skin	0.868	0.132
M23.3 Other meniscus derangements	0.867	0.133
G20 Parkinson's disease	0.866	0.134
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.862	0.138
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.860	0.140
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.850	0.150
M79.6 Pain in limb	0.839	0.161
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.839	0.161
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.838	0.162
W00-W19 Falls	0.837	0.163
M50-M54 Other dorsopathies	0.833	0.167
M65 Synovitis and tenosynovitis	0.832	0.168
S80 Superficial injury of lower leg	0.832	0.168
M72 Fibroblastic disorders	0.830	0.170
K14 Diseases of tongue	0.823	0.177
K92 Other diseases of digestive system	0.821	0.179
O46 Antepartum haemorrhage, not elsewhere classified	0.821	0.179
O00-O08 Pregnancy with abortive outcome	0.820	0.180
C77.3 Axillary and upper limb lymph nodes	0.819	0.181
S60-S69 Injuries to the wrist and hand	0.815	0.185
M67 Other disorders of synovium and tendon	0.815	0.185
C77.5 Intrapelvic lymph nodes	0.814	0.186
G45 Transient cerebral ischaemic attacks and related syndromes	0.814	0.186
T36-T50 Poisoning by drugs, medicaments and biological substances	0.814	0.186
O41 Other disorders of amniotic fluid and membranes	0.813	0.187
W20-W49 Exposure to inanimate mechanical forces	0.810	0.190
Y60-Y69 Misadventures to patients during surgical and medical care	0.809	0.191
K86 Other diseases of pancreas	0.808	0.191
O72 Postpartum haemorrhage	0.808	0.192
C15 Malignant neoplasm of oesophagus	0.808	0.192
K81 Cholecystitis	0.808	0.192
C79 Secondary malignant neoplasm of other sites	0.807	0.193
G35-G37 Demyelinating diseases of the central nervous system	0.807	0.193
O63.1 Prolonged second stage (of labour)	0.807	0.193
C77.0 Lymph nodes of head, face and neck	0.804	0.196
L83 Acanthosis nigricans	0.803	0.197
K13 Other diseases of lip and oral mucosa	0.803	0.197
L90.5 Scar conditions and fibrosis of skin	0.802	0.198
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.802	0.198
K92.1 Melaena	0.802	0.198
S82 Fracture of lower leg, including ankle	0.799	0.201
S06 Intracranial injury	0.799	0.201
L84 Corns and callosities	0.799	0.201
O85-O92 Complications predominantly related to the puerperium	0.798	0.201
O94-O99 Other obstetric conditions, not elsewhere classified	0.797	0.203
G50-G59 Nerve, nerve root and plexus disorders	0.797	0.203
O75 Other complications of labour and delivery, not elsewhere classified	0.796	0.204
O26 Maternal care for other conditions predominantly related to pregnancy	0.794	0.206
M86-M90 Other osteopathies	0.794	0.206
Chapter XXII Codes for special purposes	0.790	0.210
O42 Premature rupture of membranes	0.789	0.211
K80.8 Other cholelithiasis	0.785	0.215
S01 Open wound of head	0.785	0.215
O30 Multiple gestation	0.785	0.215
K13.0 Diseases of lips	0.784	0.215
M95.0 Acquired deformity of nose	0.783	0.217
O48 Prolonged pregnancy	0.783	0.217
G82 Paraplegia and tetraplegia	0.782	0.218
O34 Maternal care for known or suspected abnormality of pelvic organs	0.781	0.219
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.779	0.221
T15-T19 Effects of foreign body entering through natural orifice	0.778	0.222
Chapter VIII Diseases of the ear and mastoid process	0.777	0.223
L82 Seborrhoeic keratosis	0.776	0.224
M77 Other enthesopathies	0.775	0.225
K70-K77 Diseases of liver	0.775	0.225
G47 Sleep disorders	0.775	0.225
C78.7 Secondary malignant neoplasm of liver	0.775	0.225
X40-X49 Accidental poisoning by and exposure to noxious substances	0.772	0.228
L94 Other localised connective tissue disorders	0.772	0.228
M79.66 Pain in limb (Lower leg)	0.771	0.229
O62 Abnormalities of forces of labour	0.771	0.229
O66 Other obstructed labour	0.770	0.229
C25 Malignant neoplasm of pancreas	0.769	0.231
V20-V29 Motorcycle rider injured in transport accident	0.768	0.232
G90-G99 Other disorders of the nervous system	0.768	0.232
G40 Epilepsy	0.767	0.233
S83.2 Tear of meniscus, current	0.766	0.234
O16 Unspecified maternal hypertension	0.764	0.236
G80 Infantile cerebral palsy	0.763	0.237
M79.62 Pain in limb (Upper arm)	0.762	0.238
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.761	0.239
S40-S49 Injuries to the shoulder and upper arm	0.760	0.240
G83 Other paralytic syndromes	0.757	0.243
M54 Dorsalgia	0.753	0.247
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.753	0.247
M91-M94 Chondropathies	0.750	0.249
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.747	0.253
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.747	0.253
O73 Retained placenta and membranes, without haemorrhage	0.746	0.254
S02 Fracture of skull and facial bones	0.743	0.257
T79-T79 Certain early complications of trauma	0.742	0.258
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.741	0.259
L81 Other disorders of pigmentation	0.740	0.260
M66 Spontaneous rupture of synovium and tendon	0.740	0.260
M80-M85 Disorders of bone density and structure	0.740	0.260
S20-S29 Injuries to the thorax	0.739	0.261
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.739	0.261
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.738	0.262
C78.0 Secondary malignant neoplasm of lung	0.737	0.263
C15.9 Oesophagus, unspecified	0.736	0.264
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.735	0.265
K90 Intestinal malabsorption	0.733	0.267
C43-C44 Melanoma and other malignant neoplasms of skin	0.732	0.268
K14.8 Other diseases of tongue	0.732	0.268
O26.9 Pregnancy-related condition, unspecified	0.732	0.268
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.732	0.268
K82 Other diseases of gallbladder	0.732	0.268
S30 Superficial injury of abdomen, lower back and pelvis	0.731	0.269
X50-X57 Overexertion, travel and privation	0.729	0.271
S50-S59 Injuries to the elbow and forearm	0.727	0.273
K80.4 Calculus of bile duct with cholecystitis	0.725	0.275
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.725	0.275
G45.9 Transient cerebral ischaemic attack, unspecified	0.724	0.276
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.721	0.279
G00-G09 Inflammatory diseases of the central nervous system	0.719	0.281
O46.9 Antepartum haemorrhage, unspecified	0.719	0.281
X60-X84 Intentional self-harm	0.719	0.281
S81 Open wound of lower leg	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
M60-M63 Disorders of muscles	0.716	0.284
M00-M03 Infectious arthropathies	0.716	0.284
S80.9 Superficial injury of lower leg, unspecified	0.715	0.285
C51-C58 Malignant neoplasms of female genital organs	0.715	0.285
C77.8 Lymph nodes of multiple regions	0.714	0.286
K81.0 Acute cholecystitis	0.714	0.286
M15-M19 Arthrosis	0.714	0.286
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
K14.0 Glossitis	0.713	0.287
S70 Superficial injury of hip and thigh	0.713	0.287
S72 Fracture of femur	0.712	0.288
G58 Other mononeuropathies	0.711	0.289
C16 Malignant neoplasm of stomach	0.711	0.289
M22 Disorders of patella	0.709	0.291
W19 Unspecified fall	0.709	0.291
O24 Diabetes mellitus in pregnancy	0.709	0.291
V10-V19 Pedal cyclist injured in transport accident	0.709	0.291
C63 Malignant neoplasm of other and unspecified male genital organs	0.708	0.291
C60 Malignant neoplasm of penis	0.708	0.291
O74 Complications of anaesthesia during labour and delivery	0.706	0.293
O71 Other obstetric trauma	0.706	0.293
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.706	0.293
O65 Obstructed labour due to maternal pelvic abnormality	0.706	0.293
O61 Failed induction of labour	0.706	0.293
O60 Preterm delivery	0.706	0.293
O41.0 Oligohydramnios	0.706	0.294
G25 Other extrapyramidal and movement disorders	0.706	0.294
C76 Malignant neoplasm of other and ill-defined sites	0.706	0.294
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.705	0.295
S90-S99 Injuries to the ankle and foot	0.704	0.296
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.702	0.298
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.702	0.298
O00 Ectopic pregnancy	0.701	0.299
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.700	0.300
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.699	0.301
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.699	0.301
M67.8 Other specified disorders of synovium and tendon	0.699	0.301
M79.65 Pain in limb (Pelvic region and thigh)	0.699	0.301
M65.9 Synovitis and tenosynovitis, unspecified	0.697	0.303
K80.3 Calculus of bile duct with cholangitis	0.697	0.303
S66 Injury of muscle and tendon at wrist and hand level	0.695	0.305
S01.8 Open wound of other parts of head	0.692	0.308
L10-L14 Bullous disorders	0.691	0.309
M24 Other specific joint derangements	0.691	0.309
O45 Premature separation of placenta [abruptio placentae]	0.690	0.310
O44 Placenta praevia	0.690	0.310
O43 Placental disorders	0.690	0.310
O35 Maternal care for known or suspected foetal abnormality and damage	0.690	0.310
O33 Maternal care for known or suspected disproportion	0.690	0.310
O31 Complications specific to multiple gestation	0.690	0.310
O40 Polyhydramnios	0.690	0.310
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.690	0.310
Y35-Y36 Legal intervention and operations of war	0.690	0.310
Y10-Y34 Event of undetermined intent	0.690	0.310
Y00-Y09 Assault	0.690	0.310
X85-X99 Assault	0.690	0.310
X58-X59 Accidental exposure to other and unspecified factors	0.690	0.310
X30-X39 Exposure to forces of nature	0.690	0.310
X20-X29 Contact with venomous animals and plants	0.690	0.310
X10-X19 Contact with heat and hot substances	0.690	0.310
X00-X09 Exposure to smoke, fire and flames	0.690	0.310
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.690	0.310
W75-W84 Other accidental threats to breathing	0.690	0.310
W65-W74 Accidental drowning and submersion	0.690	0.310
W50-W64 Exposure to animate mechanical forces	0.690	0.310
V98-V99 Other and unspecified transport accidents	0.690	0.310
V95-V97 Air and space transport accidents	0.690	0.310
V90-V94 Water transport accidents	0.690	0.310
V80-V89 Other land transport accidents	0.690	0.310
V70-V79 Bus occupant injured in transport accident	0.690	0.310
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.690	0.310
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.690	0.310
V40-V49 Car occupant injured in transport accident	0.690	0.310
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.690	0.310
V01-V09 Pedestrian injured in transport accident	0.690	0.310
S89 Other and unspecified injuries of lower leg	0.690	0.310
S88 Traumatic amputation of lower leg	0.690	0.310
S87 Crushing injury of lower leg	0.690	0.310
S86 Injury of muscle and tendon at lower leg level	0.690	0.310
S85 Injury of blood vessels at lower leg level	0.690	0.310
S84 Injury of nerves at lower leg level	0.690	0.310
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.689	0.311
D37-D48 Neoplasms of uncertain or unknown behaviour	0.689	0.311
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.688	0.312
L95 Vasculitis limited to skin, not elsewhere classified	0.688	0.312
L93 Lupus erythematosus	0.688	0.312
L87 Transepidermal elimination disorders	0.688	0.312
L88 Pyoderma gangrenosum	0.688	0.312
L86 Keratoderma in diseases classified elsewhere	0.688	0.312
L80 Vitiligo	0.688	0.312
G70-G73 Diseases of myoneural junction and muscle	0.688	0.312
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.687	0.313
C77.4 Inguinal and lower limb lymph nodes	0.687	0.313
M70 Soft tissue disorders related to use, overuse and pressure	0.686	0.313
O63.9 Long labour, unspecified	0.686	0.314
M76 Enthesopathies of lower limb, excluding foot	0.685	0.315
M73 Soft tissue disorders in diseases classified elsewhere	0.685	0.315
W29 Contact with other powered hand tools and household machinery	0.684	0.316
M23.4 Loose body in knee	0.684	0.316
M23.5 Chronic instability of knee	0.683	0.317
G81.1 Spastic hemiplegia	0.682	0.318
G81.0 Flaccid hemiplegia	0.682	0.318
O21 Excessive vomiting in pregnancy	0.681	0.319
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.680	0.320
M71 Other bursopathies	0.679	0.321
C62 Malignant neoplasm of testis	0.679	0.321
O63.2 Delayed delivery of second twin, triplet, etc.	0.676	0.324
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.676	0.324
G43 Migraine	0.676	0.324
L92 Granulomatous disorders of skin and subcutaneous tissue	0.674	0.325
T66-T78 Other and unspecified effects of external causes	0.674	0.326
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.673	0.327
S82.4 Fracture of fibula alone	0.672	0.328
M54.9 Dorsalgia, unspecified	0.672	0.328
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.671	0.328
M79.0 Rheumatism, unspecified	0.670	0.329
G46 Vascular syndromes of brain in cerebrovascular diseases	0.670	0.330
G41 Status epilepticus	0.670	0.330
M21 Other acquired deformities of limbs	0.670	0.330
Y52 Agents primarily affecting the cardiovascular system	0.669	0.331
M79.61 Pain in limb (Shoulder region)	0.669	0.331
G47.3 Sleep apnoea	0.668	0.332
M72.2 Plantar fascial fibromatosis	0.668	0.332
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.667	0.332
W19.4 Street and highway	0.668	0.332
O69 Labour and delivery complicated by umbilical cord complications	0.667	0.333
L85 Other epidermal thickening	0.666	0.334
G44 Other headache syndromes	0.665	0.334
G24 Dystonia	0.665	0.335
G23 Other degenerative diseases of basal ganglia	0.665	0.335
G21 Secondary Parkinsonism	0.665	0.335
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.665	0.335
G22 Parkinsonism in diseases classified elsewhere	0.665	0.335
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.665	0.335
K09 Cysts of oral region, not elsewhere classified	0.663	0.337
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.663	0.337
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.662	0.338
O32 Maternal care for known or suspected malpresentation of foetus	0.660	0.340
M25 Other joint disorders, not elsewhere classified	0.660	0.340
G35 Multiple sclerosis	0.658	0.342
L50-L54 Urticaria and erythema	0.658	0.342
O30.0 Twin pregnancy	0.658	0.342
W06 Fall involving bed	0.657	0.342
T17 Foreign body in respiratory tract	0.657	0.343
M99 Biomechanical lesions, not elsewhere classified	0.657	0.343
O34.1 Maternal care for tumour of corpus uteri	0.656	0.344
O64 Obstructed labour due to malposition and malpresentation of foetus	0.656	0.344
S06.3 Focal brain injury	0.655	0.345
K76 Other diseases of liver	0.655	0.345
S08 Traumatic amputation of part of head	0.655	0.345
S07 Crushing injury of head	0.655	0.345
S05 Injury of eye and orbit	0.655	0.345
S04 Injury of cranial nerves	0.655	0.345
S03 Dislocation, sprain and strain of joints and ligaments of head	0.655	0.345
K12 Stomatitis and related lesions	0.654	0.345
S82.2 Fracture of shaft of tibia	0.654	0.346
O90 Complications of the puerperium, not elsewhere classified	0.654	0.346
M89 Other disorders of bone	0.654	0.346
W49 Exposure to other and unspecified inanimate mechanical forces	0.653	0.347
M65.4 Radial styloid tenosynovitis [de Quervain]	0.653	0.347
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.653	0.347
H90-H95 Other disorders of ear	0.652	0.348
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.652	0.348
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.651	0.349
M34 Systemic sclerosis	0.651	0.349
M33 Dermatopolymyositis	0.651	0.349
M32 Systemic lupus erythematosus	0.651	0.349
M30 Polyarteritis nodosa and related conditions	0.651	0.349
M65.3 Trigger finger	0.650	0.350
K86.1 Other chronic pancreatitis	0.649	0.351
M54.5 Low back pain	0.647	0.353
M50 Cervical disk disorders	0.646	0.353
C25.9 Pancreas, unspecified	0.646	0.354
S06.5 Traumatic subdural haemorrhage	0.646	0.354
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.646	0.354
O72.0 Third-stage haemorrhage	0.646	0.354
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.645	0.355
K93 Disorders of other digestive organs in diseases classified elsewhere	0.644	0.356
O29 Complications of anaesthesia during pregnancy	0.644	0.356
O28 Abnormal findings on antenatal screening of mother	0.644	0.356
O23 Infections of genito-urinary tract in pregnancy	0.644	0.356
O22 Venous complications in pregnancy	0.644	0.356
O25 Malnutrition in pregnancy	0.644	0.356
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.644	0.356
S72.1 Pertrochanteric fracture	0.644	0.356
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.644	0.356
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.643	0.357
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.642	0.357
T90 Sequelae of injuries of head	0.642	0.357
S80.8 Other superficial injuries of lower leg	0.642	0.358
S79 Other and unspecified injuries of hip and thigh	0.642	0.358
C25.0 Head of pancreas	0.641	0.359
K85 Acute pancreatitis	0.639	0.360
G82.2 Paraplegia, unspecified	0.639	0.361
C15.4 Middle third of oesophagus	0.638	0.362
G47.1 Disorders of excessive somnolence [hypersomnias]	0.638	0.362
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.638	0.362
L94.2 Calcinosis cutis	0.638	0.362
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.637	0.362
C78.4 Secondary malignant neoplasm of small intestine	0.637	0.362
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.637	0.362
C78.1 Secondary malignant neoplasm of mediastinum	0.637	0.362
M16 Coxarthrosis [arthrosis of hip]	0.637	0.363
S62 Fracture at wrist and hand level	0.637	0.363
C26 Malignant neoplasm of other and ill-defined digestive organs	0.637	0.363
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.636	0.363
M79.9 Soft tissue disorder, unspecified	0.636	0.364
M79.5 Residual foreign body in soft tissue	0.636	0.364
M79.4 Hypertrophy of (infrapatellar) fat pad	0.636	0.364
M79.3 Panniculitis, unspecified	0.636	0.364
M79.2 Neuralgia and neuritis, unspecified	0.636	0.364
M79.1 Myalgia	0.636	0.364
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.635	0.365
O02 Other abnormal products of conception	0.634	0.366
S01.5 Open wound of lip and oral cavity	0.634	0.366
M67.1 Other contracture of tendon (sheath)	0.633	0.367
S64 Injury of nerves at wrist and hand level	0.633	0.367
K14.9 Disease of tongue, unspecified	0.632	0.368
G40.9 Epilepsy, unspecified	0.632	0.368
K11 Diseases of salivary glands	0.631	0.369
M77.4 Metatarsalgia	0.631	0.369
S82.1 Fracture of upper end of tibia	0.631	0.369
M23.9 Internal derangement of knee, unspecified	0.630	0.369
M23.6 Other spontaneous disruption of ligament(s) of knee	0.630	0.369
M23.1 Discoid meniscus (congenital)	0.630	0.369
M23.0 Cystic meniscus	0.630	0.369
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.629	0.371
M79.7 Fibromyalgia	0.628	0.372
K06 Other disorders of gingiva and edentulous alveolar ridge	0.627	0.373
K65-K67 Diseases of peritoneum	0.627	0.373
O36 Maternal care for other known or suspected foetal problems	0.626	0.374
K03 Other diseases of hard tissues of teeth	0.626	0.374
K00 Disorders of tooth development and eruption	0.626	0.374
K20-K31 Diseases of oesophagus, stomach and duodenum	0.626	0.374
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.625	0.375
G99 Other disorders of nervous system in diseases classified elsewhere	0.625	0.375
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.624	0.376
G54 Nerve root and plexus disorders	0.624	0.376
S01.9 Open wound of head, part unspecified	0.624	0.376
S78 Traumatic amputation of hip and thigh	0.623	0.377
S77 Crushing injury of hip and thigh	0.623	0.377
S76 Injury of muscle and tendon at hip and thigh level	0.623	0.377
S75 Injury of blood vessels at hip and thigh level	0.623	0.377
S74 Injury of nerves at hip and thigh level	0.623	0.377
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.623	0.377
S71 Open wound of hip and thigh	0.623	0.377
L89 Decubitus ulcer	0.623	0.377
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.623	0.377
C21 Malignant neoplasm of anus and anal canal	0.623	0.377
C17 Malignant neoplasm of small intestine	0.623	0.377
C23 Malignant neoplasm of gallbladder	0.623	0.377
L20-L30 Dermatitis and eczema	0.622	0.378
L90.9 Atrophic disorder of skin, unspecified	0.622	0.378
L90.8 Other atrophic disorders of skin	0.622	0.378
L90.6 Striae atrophicae	0.622	0.378
L90.4 Acrodermatitis chronica atrophicans	0.622	0.378
L90.3 Atrophoderma of Pasini and Pierini	0.622	0.378
L90.2 Anetoderma of Jadassohn-Pellizzari	0.622	0.378
L90.1 Anetoderma of Schweninger-Buzzi	0.622	0.378
O20 Haemorrhage in early pregnancy	0.622	0.378
K86.0 Alcohol-induced chronic pancreatitis	0.622	0.378
L60-L75 Disorders of skin appendages	0.622	0.378
M23.37 Other meniscus derangements-Capsular lig	0.622	0.378
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.622	0.378
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.622	0.378
O62.0 Primary inadequate contractions	0.622	0.378
Y60.0 During surgical operation	0.620	0.380
G83.1 Monoplegia of lower limb	0.620	0.380
K86.9 Disease of pancreas, unspecified	0.620	0.380
L90.0 Lichen sclerosus et atrophicus	0.620	0.380
C80 Malignant neoplasm without specification of site	0.619	0.381
W13 Fall from, out of or through building or structure	0.619	0.381
C15.5 Lower third of oesophagus	0.619	0.381
G58.8 Other specified mononeuropathies	0.619	0.381
M84 Disorders of continuity of bone	0.618	0.382
S06.8 Other intracranial injuries	0.618	0.382
O15 Eclampsia	0.618	0.382
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.618	0.382
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.618	0.382
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.618	0.382
K10 Other diseases of jaws	0.617	0.383
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.616	0.383
S83.7 Injury to multiple structures of knee	0.616	0.384
S83.6 Sprain and strain of other and unspecified parts of knee	0.616	0.384
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.616	0.384
S83.3 Tear of articular cartilage of knee, current	0.616	0.384
S83.1 Dislocation of knee	0.616	0.384
S83.0 Dislocation of patella	0.616	0.384
G30-G32 Other degenerative diseases of the nervous system	0.616	0.384
K90.0 Coeliac disease	0.614	0.386
K80.0 Calculus of gallbladder with acute cholecystitis	0.613	0.387
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.612	0.388
C16.0 Cardia	0.612	0.388
O72.1 Other immediate postpartum haemorrhage	0.611	0.389
K20 Oesophagitis	0.611	0.389
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.610	0.390
S37 Injury of urinary and pelvic organs	0.610	0.390
S36 Injury of intra-abdominal organs	0.610	0.390
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.610	0.390
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.610	0.390
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.610	0.390
S31 Open wound of abdomen, lower back and pelvis	0.610	0.390
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.609	0.390
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.609	0.391
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.609	0.391
O42.9 Premature rupture of membranes, unspecified	0.608	0.392
Y51 Drugs primarily affecting the autonomic nervous system	0.607	0.393
G91 Hydrocephalus	0.607	0.393
W44 Foreign body entering into or through eye or natural orifice	0.607	0.393
T91 Sequelae of injuries of neck and trunk	0.607	0.393
H65-H75 Diseases of middle ear and mastoid	0.607	0.393
G80.9 Infantile cerebral palsy, unspecified	0.607	0.393
C44 Other malignant neoplasms of skin	0.607	0.393
S40 Superficial injury of shoulder and upper arm	0.606	0.394
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.606	0.394
K35-K38 Diseases of appendix	0.606	0.394
K70 Alcoholic liver disease	0.605	0.395
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.605	0.395
Y57 Other and unspecified drugs and medicaments	0.605	0.395
S02.0 Fracture of vault of skull	0.604	0.396
S00 Superficial injury of head	0.604	0.396
M79.8 Other specified soft tissue disorders	0.604	0.396
S60 Superficial injury of wrist and hand	0.603	0.397
G51 Facial nerve disorders	0.603	0.397
C71 Malignant neoplasm of brain	0.603	0.397
S82.0 Fracture of patella	0.602	0.398
S82.5 Fracture of medial malleolus	0.602	0.398
M79.68 Pain in limb (Other)	0.601	0.398
M79.63 Pain in limb (Forearm)	0.601	0.398
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.601	0.398

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations