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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79268501
log Bayes Factor = 16.8497
Chromosome 18   position 55,979,238  (GRCh37) Explore rs79268501 on Ensembl!
Variant rs79268501 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
T81 Complications of procedures, not elsewhere classified
0.999 0.001 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
R05 Cough
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.993 0.007 0.000
M20-M25 Other joint disorders
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.987 0.013 0.000
R00 Abnormalities of heart beat
0.986 0.014 0.000
B95-B98 Bacterial, viral and other infectious agents
0.986 0.014 0.000
I25 Chronic ischaemic heart disease
0.986 0.014 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.980 0.020 0.000
Chapter VI Diseases of the nervous system
0.978 0.022 0.000
I20 Angina pectoris
0.978 0.022 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.977 0.023 0.000
Chapter II Neoplasms
0.976 0.024 0.000
R00.0 Tachycardia, unspecified
0.975 0.025 0.000
R06 Abnormalities of breathing
0.974 0.026 0.000
A30-A49 Other bacterial diseases
0.972 0.028 0.000
C15-C26 Malignant neoplasms of digestive organs
0.970 0.030 0.000
M45-M49 Spondylopathies
0.967 0.033 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.966 0.034 0.000
S40-S49 Injuries to the shoulder and upper arm
0.953 0.047 0.000
I45 Other conduction disorders
0.951 0.049 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.951 0.049 0.000
R06.5 Mouth breathing
0.950 0.050 0.000
S00-S09 Injuries to the head
0.948 0.052 0.000
M25 Other joint disorders, not elsewhere classified
0.944 0.056 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.943 0.057 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.941 0.059 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.940 0.060 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.937 0.063 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.936 0.064 0.000
I49 Other cardiac arrhythmias
0.927 0.073 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.927 0.073 0.000
C18 Malignant neoplasm of colon
0.923 0.077 0.000
I20.9 Angina pectoris, unspecified
0.922 0.078 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.918 0.082 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.915 0.085 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.914 0.086 0.000
I45.1 Other and unspecified right bundle-branch block
0.912 0.088 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.910 0.090 0.000
R00.1 Bradycardia, unspecified
0.909 0.091 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.909 0.091 0.000
A41 Other septicaemia
0.906 0.094 0.000
G20-G26 Extrapyramidal and movement disorders
0.903 0.097 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.902 0.098 0.000
M47 Spondylosis
0.898 0.102 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.898 0.102 0.000
M48 Other spondylopathies
0.894 0.106 0.000
C20 Malignant neoplasm of rectum
0.890 0.110 0.000
A49 Bacterial infection of unspecified site
0.890 0.110 0.000
G50 Disorders of trigeminal nerve
0.888 0.112 0.000
S60-S69 Injuries to the wrist and hand
0.887 0.113 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.886 0.114 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.885 0.115 0.000
M25.4 Effusion of joint
0.881 0.119 0.000
S80-S89 Injuries to the knee and lower leg
0.876 0.124 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.876 0.124 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.875 0.125 0.000
Y83.8 Other surgical procedures
0.875 0.125 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.873 0.127 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.872 0.128 0.000
S01 Open wound of head
0.871 0.129 0.000
G40-G47 Episodic and paroxysmal disorders
0.870 0.130 0.000
O00-O08 Pregnancy with abortive outcome
0.869 0.131 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.867 0.133 0.000
M47.8 Other spondylosis
0.866 0.134 0.000
I20.8 Other forms of angina pectoris
0.865 0.135 0.000
I20.1 Angina pectoris with documented spasm
0.859 0.141 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.856 0.144 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.856 0.144 0.000
I25.3 Aneurysm of heart
0.855 0.145 0.000
R04 Haemorrhage from respiratory passages
0.854 0.146 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.852 0.148 0.000
D60-D64 Aplastic and other anaemias
0.852 0.148 0.000
I25.2 Old myocardial infarction
0.849 0.151 0.000
G50.0 Trigeminal neuralgia
0.849 0.151 0.000
S90-S99 Injuries to the ankle and foot
0.847 0.153 0.000
M48.0 Spinal stenosis
0.842 0.158 0.000
M22 Disorders of patella
0.842 0.158 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.841 0.159 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.839 0.161 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.838 0.162 0.000
I49.5 Sick sinus syndrome
0.837 0.163 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.836 0.164 0.000
C16 Malignant neoplasm of stomach
0.836 0.164 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.835 0.165 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.834 0.166 0.000
S50-S59 Injuries to the elbow and forearm
0.834 0.166 0.000
C18.4 Transverse colon
0.834 0.166 0.000
B25-B34 Other viral diseases
0.829 0.171 0.000
M24 Other specific joint derangements
0.827 0.173 0.000
I49.9 Cardiac arrhythmia, unspecified
0.823 0.177 0.000
M20 Acquired deformities of fingers and toes
0.823 0.177 0.000
I31 Other diseases of pericardium
0.822 0.178 0.000
A49.0 Staphylococcal infection, unspecified
0.821 0.179 0.000
D45 Polycythaemia vera
0.821 0.179 0.000
S06 Intracranial injury
0.820 0.180 0.000
S43.0 Dislocation of shoulder joint
0.819 0.181 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.819 0.181 0.000
I42 Cardiomyopathy
0.816 0.184 0.000
I45.5 Other specified heart block
0.815 0.185 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.811 0.189 0.000
O03 Spontaneous abortion
0.811 0.189 0.000
I51 Complications and ill-defined descriptions of heart disease
0.810 0.190 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.809 0.191 0.000
R06.4 Hyperventilation
0.808 0.192 0.000
I77 Other disorders of arteries and arterioles
0.808 0.192 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.808 0.192 0.000
Y83.4 Other reconstructive surgery
0.808 0.192 0.000
I24 Other acute ischaemic heart diseases
0.807 0.193 0.000
G25 Other extrapyramidal and movement disorders
0.804 0.196 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.802 0.198 0.000
R04.0 Epistaxis
0.802 0.198 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.801 0.199 0.000
M47.86 Other spondylosis (Lumbar region)
0.801 0.199 0.000
S01.8 Open wound of other parts of head
0.800 0.200 0.000
M31 Other necrotising vasculopathies
0.800 0.200 0.000
S68 Traumatic amputation of wrist and hand
0.799 0.201 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.799 0.201 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.798 0.202 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.797 0.203 0.000
Chapter XXII Codes for special purposes
0.797 0.203 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.796 0.204 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.796 0.204 0.000
M20.2 Hallux rigidus
0.794 0.206 0.000
D64 Other anaemias
0.794 0.206 0.000
X60-X84 Intentional self-harm
0.793 0.207 0.000
I71 Aortic aneurysm and dissection
0.793 0.207 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.793 0.207 0.000
C18.6 Descending colon
0.793 0.207 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.791 0.209 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.790 0.210 0.000
M25.7 Osteophyte
0.789 0.211 0.000
M25.46 Effusion of joint (Lower leg)
0.788 0.212 0.000
T79-T79 Certain early complications of trauma
0.788 0.212 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.787 0.213 0.000
C22.0 Liver cell carcinoma
0.787 0.213 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.785 0.215 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.785 0.215 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.784 0.216 0.000
I30 Acute pericarditis
0.780 0.220 0.000
R06.2 Wheezing
0.780 0.220 0.000
S10-S19 Injuries to the neck
0.778 0.222 0.000
R09.2 Respiratory arrest
0.778 0.222 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.777 0.223 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.775 0.225 0.000
O03.9 Complete or unspecified, without complication
0.774 0.226 0.000
C18.5 Splenic flexure
0.774 0.226 0.000
C18.2 Ascending colon
0.773 0.227 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.772 0.228 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.772 0.228 0.000
M35 Other systemic involvement of connective tissue
0.771 0.229 0.000
I10-I15 Hypertensive diseases
0.771 0.229 0.000
I72 Other aneurysm
0.771 0.229 0.000
M49 Spondylopathies in diseases classified elsewhere
0.769 0.231 0.000
M21 Other acquired deformities of limbs
0.768 0.232 0.000
S82 Fracture of lower leg, including ankle
0.768 0.232 0.000
S42 Fracture of shoulder and upper arm
0.768 0.232 0.000
D50-D53 Nutritional anaemias
0.767 0.233 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.765 0.235 0.000
M91-M94 Chondropathies
0.765 0.235 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.764 0.236 0.000
M65-M68 Disorders of synovium and tendon
0.763 0.237 0.000
T81.9 Unspecified complication of procedure
0.762 0.238 0.000
G20 Parkinson's disease
0.762 0.238 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.761 0.238 0.000
I25.5 Ischaemic cardiomyopathy
0.760 0.240 0.000
M25.47 Effusion of joint (Ankle and foot)
0.759 0.241 0.000
I47 Paroxysmal tachycardia
0.756 0.244 0.000
M86-M90 Other osteopathies
0.756 0.244 0.000
S20-S29 Injuries to the thorax
0.754 0.246 0.000
T86 Failure and rejection of transplanted organs and tissues
0.753 0.247 0.000
D64.9 Anaemia, unspecified
0.752 0.248 0.000
S02 Fracture of skull and facial bones
0.752 0.248 0.000
T39.1 4-Aminophenol derivatives
0.751 0.249 0.000
R47-R49 Symptoms and signs involving speech and voice
0.750 0.250 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.750 0.250 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.749 0.251 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.749 0.251 0.000
M48.06 Spinal stenosis (Lumbar region)
0.745 0.255 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.744 0.256 0.000
G45.4 Transient global amnesia
0.744 0.256 0.000
T40.2 Other opioids
0.743 0.257 0.000
Y84.2 Radiological procedure and radiotherapy
0.743 0.257 0.000
R06.1 Stridor
0.742 0.258 0.000
M22.2 Patellofemoral disorders
0.741 0.259 0.000
I45.2 Bifascicular block
0.739 0.261 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.739 0.261 0.000
I60-I69 Cerebrovascular diseases
0.739 0.261 0.000
S92 Fracture of foot, except ankle
0.738 0.262 0.000
X20-X29 Contact with venomous animals and plants
0.737 0.263 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.736 0.264 0.000
I95 Hypotension
0.736 0.264 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.736 0.264 0.000
S41 Open wound of shoulder and upper arm
0.734 0.266 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.732 0.268 0.000
W20-W49 Exposure to inanimate mechanical forces
0.732 0.268 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.731 0.269 0.000
O02 Other abnormal products of conception
0.731 0.269 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.731 0.269 0.000
C18.3 Hepatic flexure
0.730 0.270 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.730 0.270 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.728 0.272 0.000
V10-V19 Pedal cyclist injured in transport accident
0.727 0.273 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.725 0.275 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.723 0.277 0.000
I22 Subsequent myocardial infarction
0.722 0.277 0.000
Y84.6 Urinary catheterisation
0.722 0.278 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.721 0.279 0.000
M47.82 Other spondylosis (Cervical region)
0.721 0.279 0.000
D37.4 Colon
0.720 0.280 0.000
M25.5 Pain in joint
0.719 0.281 0.000
C78.2 Secondary malignant neoplasm of pleura
0.719 0.281 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.719 0.281 0.000
C16.9 Stomach, unspecified
0.718 0.282 0.000
M40-M43 Deforming dorsopathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.716 0.284 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.716 0.284 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.716 0.284 0.000
T85.2 Mechanical complication of intraocular lens
0.716 0.284 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
I78 Diseases of capillaries
0.713 0.286 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.288 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.712 0.288 0.000
A41.9 Septicaemia, unspecified
0.712 0.288 0.000
I70 Atherosclerosis
0.711 0.289 0.000
I05-I09 Chronic rheumatic heart diseases
0.711 0.289 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.710 0.290 0.000
M70-M79 Other soft tissue disorders
0.710 0.290 0.000
I49.0 Ventricular fibrillation and flutter
0.709 0.291 0.000
T66-T78 Other and unspecified effects of external causes
0.709 0.291 0.000
B35-B49 Mycoses
0.709 0.291 0.000
M20.4 Other hammer toe(s) (acquired)
0.708 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.708 0.292 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
M34 Systemic sclerosis
0.708 0.292 0.000
M33 Dermatopolymyositis
0.708 0.292 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.708 0.292 0.000
B34 Viral infection of unspecified site
0.708 0.292 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.292 0.000
I48 Atrial fibrillation and flutter
0.707 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.292 0.000
I40 Acute myocarditis
0.707 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.292 0.000
I37 Pulmonary valve disorders
0.707 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.292 0.000
I25.6 Silent myocardial ischaemia
0.707 0.293 0.000
I25.4 Coronary artery aneurysm
0.707 0.293 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.707 0.293 0.000
D50 Iron deficiency anaemia
0.707 0.293 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.706 0.294 0.000
I24.8 Other forms of acute ischaemic heart disease
0.703 0.297 0.000
A46 Erysipelas
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.701 0.299 0.000
D37.1 Stomach
0.701 0.299 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.700 0.300 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.700 0.300 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.700 0.300 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.700 0.300 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.700 0.300 0.000
R06.7 Sneezing
0.698 0.302 0.000
R06.6 Hiccough
0.698 0.302 0.000
R06.3 Periodic breathing
0.698 0.302 0.000
A48 Other bacterial diseases, not elsewhere classified
0.697 0.303 0.000
A44 Bartonellosis
0.697 0.303 0.000
A43 Nocardiosis
0.697 0.303 0.000
A42 Actinomycosis
0.697 0.303 0.000
A40 Streptococcal septicaemia
0.697 0.303 0.000
A39 Meningococcal infection
0.697 0.303 0.000
A37 Whooping cough
0.697 0.303 0.000
A36 Diphtheria
0.697 0.303 0.000
A32 Listeriosis
0.697 0.303 0.000
A31 Infection due to other mycobacteria
0.697 0.303 0.000
A30 Leprosy [Hansen's disease]
0.697 0.303 0.000
A38 Scarlet fever
0.697 0.303 0.000
A35 Other tetanus
0.697 0.303 0.000
A34 Obstetrical tetanus
0.697 0.303 0.000
A33 Tetanus neonatorum
0.697 0.303 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.697 0.303 0.000
S42.2 Fracture of upper end of humerus
0.696 0.304 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.695 0.305 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.695 0.305 0.000
C21 Malignant neoplasm of anus and anal canal
0.695 0.305 0.000
C17 Malignant neoplasm of small intestine
0.695 0.305 0.000
C23 Malignant neoplasm of gallbladder
0.695 0.305 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.695 0.305 0.000
S62 Fracture at wrist and hand level
0.695 0.305 0.000
S64 Injury of nerves at wrist and hand level
0.695 0.305 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.693 0.307 0.000
C78.0 Secondary malignant neoplasm of lung
0.692 0.308 0.000
R09.1 Pleurisy
0.692 0.308 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.692 0.308 0.000
S09 Other and unspecified injuries of head
0.691 0.309 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.309 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.690 0.310 0.000
S01.5 Open wound of lip and oral cavity
0.689 0.311 0.000
S82.3 Fracture of lower end of tibia
0.688 0.312 0.000
C34 Malignant neoplasm of bronchus and lung
0.688 0.312 0.000
M24.5 Contracture of joint
0.687 0.313 0.000
D46 Myelodysplastic syndromes
0.687 0.313 0.000
I51.7 Cardiomegaly
0.685 0.315 0.000
Y84.1 Kidney dialysis
0.685 0.315 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.685 0.315 0.000
D41.4 Bladder
0.685 0.315 0.000
G25.3 Myoclonus
0.685 0.315 0.000
S01.2 Open wound of nose
0.684 0.316 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.684 0.316 0.000
Y84.8 Other medical procedures
0.684 0.316 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.683 0.317 0.000
S48 Traumatic amputation of shoulder and upper arm
0.683 0.317 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.683 0.317 0.000
S44 Injury of nerves at shoulder and upper arm level
0.683 0.317 0.000
S40 Superficial injury of shoulder and upper arm
0.683 0.317 0.000
S47 Crushing injury of shoulder and upper arm
0.683 0.317 0.000
R06.8 Other and unspecified abnormalities of breathing
0.683 0.317 0.000
I45.8 Other specified conduction disorders
0.682 0.318 0.000
I45.4 Nonspecific intraventricular block
0.682 0.318 0.000
I45.3 Trifascicular block
0.682 0.318 0.000
I45.0 Right fascicular block
0.682 0.318 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.682 0.318 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.682 0.318 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.682 0.318 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.682 0.318 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.682 0.318 0.000
M22.8 Other disorders of patella
0.681 0.318 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.681 0.319 0.000
S89 Other and unspecified injuries of lower leg
0.681 0.319 0.000
G57 Mononeuropathies of lower limb
0.681 0.319 0.000
M25.51 Pain in joint (Shoulder region)
0.680 0.320 0.000
S08 Traumatic amputation of part of head
0.680 0.320 0.000
S07 Crushing injury of head
0.680 0.320 0.000
S05 Injury of eye and orbit
0.680 0.320 0.000
S04 Injury of cranial nerves
0.680 0.320 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.680 0.320 0.000
W00-W19 Falls
0.679 0.321 0.000
R40 Somnolence, stupor and coma
0.679 0.321 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.678 0.322 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.678 0.322 0.000
R09.0 Asphyxia
0.678 0.322 0.000
M80-M85 Disorders of bone density and structure
0.677 0.323 0.000
I42.9 Cardiomyopathy, unspecified
0.677 0.323 0.000
M25.9 Joint disorder, unspecified
0.677 0.323 0.000
M25.8 Other specified joint disorders
0.677 0.323 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.677 0.323 0.000
M25.3 Other instability of joint
0.677 0.323 0.000
M25.2 Flail joint
0.677 0.323 0.000
M25.1 Fistula of joint
0.677 0.323 0.000
M25.0 Haemarthrosis
0.677 0.323 0.000
M48.09 Spinal stenosis (Site unspecified)
0.677 0.323 0.000
G54 Nerve root and plexus disorders
0.676 0.324 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.676 0.324 0.000
G52 Disorders of other cranial nerves
0.676 0.324 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.676 0.324 0.000
G58 Other mononeuropathies
0.676 0.324 0.000
A49.8 Other bacterial infections of unspecified site
0.676 0.324 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.676 0.324 0.000
S51 Open wound of forearm
0.675 0.325 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.674 0.325 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.674 0.325 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.674 0.325 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.674 0.325 0.000
G56 Mononeuropathies of upper limb
0.674 0.326 0.000
Y83.5 Amputation of limb(s)
0.674 0.326 0.000
Y83.0 Surgical operation with transplant of whole organ
0.674 0.326 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.674 0.326 0.000
S82.1 Fracture of upper end of tibia
0.673 0.327 0.000
M47.1 Other spondylosis with myelopathy
0.671 0.328 0.000
G70-G73 Diseases of myoneural junction and muscle
0.671 0.329 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.671 0.329 0.000
R23 Other skin changes
0.671 0.329 0.000
I95.9 Hypotension, unspecified
0.671 0.329 0.000
C51-C58 Malignant neoplasms of female genital organs
0.670 0.330 0.000
I31.3 Pericardial effusion (noninflammatory)
0.670 0.330 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.669 0.331 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.669 0.331 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.669 0.331 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.668 0.332 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.668 0.332 0.000
I49.8 Other specified cardiac arrhythmias
0.666 0.334 0.000
C80 Malignant neoplasm without specification of site
0.666 0.334 0.000
I49.2 Junctional premature depolarisation
0.665 0.335 0.000
I49.1 Atrial premature depolarisation
0.665 0.335 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.664 0.336 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.664 0.336 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.664 0.336 0.000
M25.77 Osteophyte (Ankle and foot)
0.663 0.337 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.663 0.337 0.000
S69 Other and unspecified injuries of wrist and hand
0.663 0.337 0.000
M46 Other inflammatory spondylopathies
0.663 0.337 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.663 0.337 0.000
C18.8 Overlapping lesion of colon
0.662 0.338 0.000
C18.1 Appendix
0.662 0.338 0.000
D61 Other aplastic anaemias
0.660 0.340 0.000
S01.9 Open wound of head, part unspecified
0.660 0.340 0.000
I47.2 Ventricular tachycardia
0.660 0.340 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.658 0.342 0.000
I77.1 Stricture of artery
0.657 0.343 0.000
D55-D59 Haemolytic anaemias
0.656 0.344 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.655 0.345 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.655 0.345 0.000
Chapter XIV Diseases of the genitourinary system
0.655 0.345 0.000
S06.9 Intracranial injury, unspecified
0.654 0.346 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.653 0.347 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.653 0.347 0.000
O85-O92 Complications predominantly related to the puerperium
0.652 0.347 0.000
D50.8 Other iron deficiency anaemias
0.652 0.348 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.651 0.348 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.651 0.348 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.651 0.348 0.000
T83.2 Mechanical complication of graft of urinary organ
0.651 0.348 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.651 0.349 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.651 0.349 0.000
M35.0 Sicca syndrome [Sjogren]
0.650 0.350 0.000
A41.4 Septicaemia due to anaerobes
0.650 0.350 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.650 0.350 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.650 0.350 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.649 0.351 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.649 0.351 0.000
R86 Abnormal findings in specimens from male genital organs
0.648 0.352 0.000
I33 Acute and subacute endocarditis
0.648 0.352 0.000
O04 Medical abortion
0.648 0.352 0.000
G24 Dystonia
0.647 0.353 0.000
G23 Other degenerative diseases of basal ganglia
0.647 0.353 0.000
G21 Secondary Parkinsonism
0.647 0.353 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.647 0.353 0.000
G22 Parkinsonism in diseases classified elsewhere
0.647 0.353 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.646 0.353 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.353 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.646 0.353 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.646 0.353 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.646 0.353 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.646 0.353 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.353 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.646 0.353 0.000
T36 Poisoning by systemic antibiotics
0.646 0.353 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.646 0.354 0.000
C22.9 Liver, unspecified
0.645 0.355 0.000
S42.20 Fracture of upper end of humerus (closed)
0.644 0.356 0.000
R49 Voice disturbances
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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