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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80002652
log Bayes Factor = 18.6612
Chromosome 12   position 107,437,422  (GRCh37) Explore rs80002652 on Ensembl!
Variant rs80002652 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Z51 Other medical care
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
Z51.2 Other chemotherapy
0.985 0.015 0.000
C78.0 Secondary malignant neoplasm of lung
0.984 0.016 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.982 0.018 0.000
C79 Secondary malignant neoplasm of other sites
0.981 0.019 0.000
S00-S09 Injuries to the head
0.979 0.021 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.977 0.023 0.000
Z46 Fitting and adjustment of other devices
0.976 0.024 0.000
Chapter VII Diseases of the eye and adnexa
0.968 0.032 0.000
O60-O75 Complications of labour and delivery
0.966 0.034 0.000
C78.7 Secondary malignant neoplasm of liver
0.965 0.035 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.961 0.039 0.000
Z46.6 Fitting and adjustment of urinary device
0.959 0.041 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.956 0.044 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.952 0.048 0.000
E20-E35 Disorders of other endocrine glands
0.948 0.052 0.000
Z51.0 Radiotherapy session
0.946 0.054 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.944 0.056 0.000
S06 Intracranial injury
0.944 0.056 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.942 0.058 0.000
Chapter IX Diseases of the circulatory system
0.941 0.059 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.941 0.059 0.000
I95 Hypotension
0.940 0.060 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.940 0.060 0.000
D60-D64 Aplastic and other anaemias
0.936 0.064 0.000
Z51.5 Palliative care
0.933 0.067 0.000
C78.2 Secondary malignant neoplasm of pleura
0.933 0.067 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.931 0.069 0.000
I95.9 Hypotension, unspecified
0.930 0.070 0.000
E65-E68 Obesity and other hyperalimentation
0.924 0.076 0.000
E10-E14 Diabetes mellitus
0.919 0.081 0.000
G90-G99 Other disorders of the nervous system
0.918 0.082 0.000
Z45 Adjustment and management of implanted device
0.918 0.082 0.000
Chapter X Diseases of the respiratory system
0.910 0.090 0.000
S02 Fracture of skull and facial bones
0.905 0.095 0.000
S80-S89 Injuries to the knee and lower leg
0.904 0.096 0.000
C77.5 Intrapelvic lymph nodes
0.903 0.097 0.000
Z51.3 Blood transfusion without reported diagnosis
0.902 0.098 0.000
O36 Maternal care for other known or suspected foetal problems
0.895 0.105 0.000
Y43 Primarily systemic agents
0.894 0.106 0.000
H43-H45 Disorders of vitreous body and globe
0.882 0.118 0.000
C34 Malignant neoplasm of bronchus and lung
0.882 0.118 0.000
Z47 Other orthopaedic follow-up care
0.880 0.120 0.000
M40-M43 Deforming dorsopathies
0.879 0.121 0.000
D70 Agranulocytosis
0.877 0.123 0.000
Chapter I Certain infectious and parasitic diseases
0.877 0.123 0.000
C51-C58 Malignant neoplasms of female genital organs
0.875 0.125 0.000
E66 Obesity
0.875 0.125 0.000
I95.1 Orthostatic hypotension
0.875 0.125 0.000
C77.3 Axillary and upper limb lymph nodes
0.865 0.135 0.000
D69 Purpura and other haemorrhagic conditions
0.865 0.135 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.862 0.138 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.862 0.138 0.000
C77.1 Intrathoracic lymph nodes
0.861 0.139 0.000
G20-G26 Extrapyramidal and movement disorders
0.859 0.141 0.000
J00-J06 Acute upper respiratory infections
0.859 0.141 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.858 0.142 0.000
Z45.2 Adjustment and management of vascular access device
0.855 0.145 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.854 0.146 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.853 0.147 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.851 0.149 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.850 0.150 0.000
O00-O08 Pregnancy with abortive outcome
0.847 0.153 0.000
M45-M49 Spondylopathies
0.845 0.155 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.842 0.158 0.000
J60-J70 Lung diseases due to external agents
0.838 0.162 0.000
E11 Non-insulin-dependent diabetes mellitus
0.838 0.162 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.836 0.164 0.000
Z49 Care involving dialysis
0.835 0.165 0.000
Y43.3 Other antineoplastic drugs
0.835 0.165 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.834 0.166 0.000
M20-M25 Other joint disorders
0.831 0.169 0.000
H43 Disorders of vitreous body
0.829 0.171 0.000
E66.8 Other obesity
0.829 0.171 0.000
M80-M85 Disorders of bone density and structure
0.827 0.173 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.825 0.175 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.823 0.177 0.000
S00 Superficial injury of head
0.820 0.180 0.000
D68 Other coagulation defects
0.817 0.183 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.817 0.183 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.816 0.184 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.816 0.184 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.815 0.185 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.815 0.185 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.814 0.186 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.812 0.188 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.812 0.188 0.000
C64-C68 Malignant neoplasms of urinary tract
0.810 0.190 0.000
H02 Other disorders of eyelid
0.808 0.192 0.000
E23 Hypofunction and other disorders of pituitary gland
0.808 0.192 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.807 0.193 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.806 0.194 0.000
O85-O92 Complications predominantly related to the puerperium
0.804 0.196 0.000
S70-S79 Injuries to the hip and thigh
0.803 0.197 0.000
I95.2 Hypotension due to drugs
0.802 0.198 0.000
J20-J22 Other acute lower respiratory infections
0.800 0.200 0.000
M43 Other deforming dorsopathies
0.799 0.201 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.799 0.201 0.000
T79-T79 Certain early complications of trauma
0.798 0.202 0.000
D64 Other anaemias
0.796 0.204 0.000
Y52 Agents primarily affecting the cardiovascular system
0.796 0.204 0.000
S06.5 Traumatic subdural haemorrhage
0.793 0.207 0.000
W50-W64 Exposure to animate mechanical forces
0.792 0.208 0.000
Z42 Follow-up care involving plastic surgery
0.791 0.209 0.000
E34 Other endocrine disorders
0.788 0.212 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.787 0.213 0.000
Z41 Procedures for purposes other than remedying health state
0.784 0.216 0.000
C34.1 Upper lobe, bronchus or lung
0.784 0.216 0.000
H10-H13 Disorders of conjunctiva
0.784 0.216 0.000
S82 Fracture of lower leg, including ankle
0.783 0.217 0.000
G93 Other disorders of brain
0.783 0.217 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.783 0.217 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.782 0.218 0.000
J06.9 Acute upper respiratory infection, unspecified
0.781 0.219 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.781 0.219 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.780 0.220 0.000
E70-E90 Metabolic disorders
0.779 0.221 0.000
S06.2 Diffuse brain injury
0.776 0.224 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.776 0.224 0.000
C34.9 Bronchus or lung, unspecified
0.776 0.224 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.776 0.224 0.000
M47 Spondylosis
0.773 0.227 0.000
O36.8 Maternal care for other specified foetal problems
0.771 0.229 0.000
O72 Postpartum haemorrhage
0.770 0.230 0.000
O70 Perineal laceration during delivery
0.767 0.233 0.000
D00-D09 In situ neoplasms
0.767 0.233 0.000
Y57 Other and unspecified drugs and medicaments
0.766 0.234 0.000
E10 Insulin-dependent diabetes mellitus
0.764 0.236 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.764 0.236 0.000
B35-B49 Mycoses
0.764 0.236 0.000
H55-H59 Other disorders of eye and adnexa
0.764 0.236 0.000
O03 Spontaneous abortion
0.762 0.238 0.000
E24 Cushing's syndrome
0.761 0.239 0.000
Y40 Systemic antibiotics
0.761 0.239 0.000
S06.8 Other intracranial injuries
0.759 0.241 0.000
H43.8 Other disorders of vitreous body
0.758 0.242 0.000
E11.3 With ophthalmic complications
0.757 0.243 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.757 0.243 0.000
A30-A49 Other bacterial diseases
0.757 0.243 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.756 0.243 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.756 0.244 0.000
C77.2 Intra-abdominal lymph nodes
0.756 0.244 0.000
E27 Other disorders of adrenal gland
0.756 0.244 0.000
Chapter XXII Codes for special purposes
0.756 0.244 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.755 0.245 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.753 0.247 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.752 0.248 0.000
Z50 Care involving use of rehabilitation procedures
0.752 0.248 0.000
O36.6 Maternal care for excessive foetal growth
0.751 0.249 0.000
G91 Hydrocephalus
0.751 0.249 0.000
O43 Placental disorders
0.751 0.249 0.000
Y45.0 Opioids and related analgesics
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.750 0.250 0.000
G51 Facial nerve disorders
0.748 0.252 0.000
O64.1 Obstructed labour due to breech presentation
0.748 0.252 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.746 0.254 0.000
S06.3 Focal brain injury
0.746 0.254 0.000
E28 Ovarian dysfunction
0.746 0.254 0.000
S10-S19 Injuries to the neck
0.745 0.254 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.745 0.255 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.745 0.255 0.000
D75 Other diseases of blood and blood-forming organs
0.745 0.255 0.000
M91-M94 Chondropathies
0.744 0.255 0.000
S50-S59 Injuries to the elbow and forearm
0.744 0.256 0.000
S40-S49 Injuries to the shoulder and upper arm
0.743 0.257 0.000
J69 Pneumonitis due to solids and liquids
0.742 0.258 0.000
H02.8 Other specified disorders of eyelid
0.742 0.258 0.000
M43.1 Spondylolisthesis
0.741 0.259 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.740 0.260 0.000
S20-S29 Injuries to the thorax
0.739 0.261 0.000
W00-W19 Falls
0.739 0.261 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.738 0.262 0.000
C79.2 Secondary malignant neoplasm of skin
0.738 0.262 0.000
S02.1 Fracture of base of skull
0.738 0.262 0.000
O66 Other obstructed labour
0.736 0.264 0.000
C77.0 Lymph nodes of head, face and neck
0.735 0.265 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.734 0.266 0.000
O42 Premature rupture of membranes
0.734 0.266 0.000
G81 Hemiplegia
0.734 0.266 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.734 0.266 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.734 0.266 0.000
G25 Other extrapyramidal and movement disorders
0.731 0.269 0.000
Chapter VIII Diseases of the ear and mastoid process
0.731 0.269 0.000
O36.9 Maternal care for foetal problem, unspecified
0.731 0.269 0.000
O73 Retained placenta and membranes, without haemorrhage
0.729 0.271 0.000
S02.0 Fracture of vault of skull
0.728 0.272 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.728 0.272 0.000
O40 Polyhydramnios
0.727 0.272 0.000
S89 Other and unspecified injuries of lower leg
0.727 0.272 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.727 0.273 0.000
D72 Other disorders of white blood cells
0.726 0.274 0.000
I71 Aortic aneurysm and dissection
0.726 0.274 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.726 0.274 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.725 0.275 0.000
H43.1 Vitreous haemorrhage
0.725 0.275 0.000
E22 Hyperfunction of pituitary gland
0.725 0.275 0.000
D80-D89 Certain disorders involving the immune mechanism
0.723 0.276 0.000
H02.4 Ptosis of eyelid
0.723 0.277 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.723 0.277 0.000
Z45.1 Adjustment and management of infusion pump
0.723 0.277 0.000
S02.2 Fracture of nasal bones
0.722 0.278 0.000
J22 Unspecified acute lower respiratory infection
0.722 0.278 0.000
Z51.1 Chemotherapy session for neoplasm
0.721 0.279 0.000
I99 Other and unspecified disorders of circulatory system
0.720 0.280 0.000
D69.9 Haemorrhagic condition, unspecified
0.718 0.282 0.000
Z40 Prophylactic surgery
0.718 0.282 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
Z51.9 Medical care, unspecified
0.716 0.283 0.000
Z51.6 Desensitisation to allergens
0.716 0.283 0.000
C56 Malignant neoplasm of ovary
0.717 0.283 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.716 0.284 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.716 0.284 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.715 0.285 0.000
D55-D59 Haemolytic anaemias
0.714 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.714 0.285 0.000
M65-M68 Disorders of synovium and tendon
0.714 0.286 0.000
D68.8 Other specified coagulation defects
0.714 0.286 0.000
S02.8 Fractures of other skull and facial bones
0.713 0.287 0.000
Z47.8 Other specified orthopaedic follow-up care
0.713 0.287 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.712 0.287 0.000
G70-G73 Diseases of myoneural junction and muscle
0.712 0.288 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.712 0.288 0.000
D63.0 Anaemia in neoplastic disease
0.712 0.288 0.000
C60-C63 Malignant neoplasms of male genital organs
0.711 0.289 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
C92 Myeloid leukaemia
0.711 0.289 0.000
S80 Superficial injury of lower leg
0.710 0.290 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X60-X84 Intentional self-harm
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X50-X57 Overexertion, travel and privation
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.709 0.291 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.707 0.293 0.000
E23.0 Hypopituitarism
0.707 0.293 0.000
S82.3 Fracture of lower end of tibia
0.707 0.293 0.000
E29 Testicular dysfunction
0.706 0.294 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.706 0.294 0.000
O70.0 First degree perineal laceration during delivery
0.705 0.295 0.000
E50-E64 Other nutritional deficiencies
0.705 0.295 0.000
Y44 Agents primarily affecting blood constituents
0.704 0.296 0.000
C34.2 Middle lobe, bronchus or lung
0.704 0.296 0.000
C77.8 Lymph nodes of multiple regions
0.704 0.296 0.000
C79.6 Secondary malignant neoplasm of ovary
0.703 0.297 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.703 0.297 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.703 0.297 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.703 0.297 0.000
D62 Acute posthaemorrhagic anaemia
0.703 0.297 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.703 0.297 0.000
S09 Other and unspecified injuries of head
0.702 0.298 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.702 0.298 0.000
S08 Traumatic amputation of part of head
0.702 0.298 0.000
S07 Crushing injury of head
0.702 0.298 0.000
S05 Injury of eye and orbit
0.702 0.298 0.000
S04 Injury of cranial nerves
0.702 0.298 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.702 0.298 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.702 0.298 0.000
G95 Other diseases of spinal cord
0.701 0.299 0.000
C53 Malignant neoplasm of cervix uteri
0.701 0.299 0.000
S81 Open wound of lower leg
0.701 0.299 0.000
Y59 Other and unspecified vaccines and biological substances
0.700 0.300 0.000
Y58 Bacterial vaccines
0.700 0.300 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.700 0.300 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.700 0.300 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.700 0.300 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.700 0.300 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.700 0.300 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.700 0.300 0.000
Y48 Anaesthetics and therapeutic gases
0.700 0.300 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.700 0.300 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.700 0.300 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.700 0.300 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.700 0.300 0.000
Z46.8 Fitting and adjustment of other specified devices
0.700 0.300 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.700 0.300 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.700 0.300 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.700 0.300 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.700 0.300 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.700 0.300 0.000
Z46.1 Fitting and adjustment of hearing aid
0.700 0.300 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.700 0.300 0.000
E83 Disorders of mineral metabolism
0.700 0.300 0.000
H30-H36 Disorders of choroid and retina
0.699 0.301 0.000
M47.9 Spondylosis, unspecified
0.699 0.301 0.000
O03.9 Complete or unspecified, without complication
0.698 0.302 0.000
M41 Scoliosis
0.697 0.303 0.000
I73 Other peripheral vascular diseases
0.697 0.303 0.000
D64.9 Anaemia, unspecified
0.696 0.304 0.000
C91 Lymphoid leukaemia
0.694 0.306 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.694 0.306 0.000
M25 Other joint disorders, not elsewhere classified
0.693 0.307 0.000
O74 Complications of anaesthesia during labour and delivery
0.692 0.307 0.000
O71 Other obstetric trauma
0.692 0.307 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.692 0.307 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.692 0.307 0.000
O62 Abnormalities of forces of labour
0.692 0.307 0.000
O61 Failed induction of labour
0.692 0.307 0.000
O60 Preterm delivery
0.692 0.307 0.000
A41 Other septicaemia
0.692 0.308 0.000
Z52 Donors of organs and tissues
0.691 0.309 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.690 0.309 0.000
M60-M63 Disorders of muscles
0.689 0.311 0.000
M00-M03 Infectious arthropathies
0.689 0.311 0.000
E66.9 Obesity, unspecified
0.689 0.311 0.000
G12 Spinal muscular atrophy and related syndromes
0.689 0.311 0.000
Z39 Postpartum care and examination
0.689 0.311 0.000
Z49.1 Extracorporeal dialysis
0.688 0.311 0.000
J95-J99 Other diseases of the respiratory system
0.687 0.313 0.000
G30-G32 Other degenerative diseases of the nervous system
0.685 0.315 0.000
M86-M90 Other osteopathies
0.685 0.315 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.685 0.315 0.000
Y45.2 Propionic acid derivatives
0.684 0.316 0.000
S02.4 Fracture of malar and maxillary bones
0.684 0.316 0.000
B95-B98 Bacterial, viral and other infectious agents
0.683 0.317 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.682 0.317 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.682 0.318 0.000
C95 Leukaemia of unspecified cell type
0.682 0.318 0.000
C94 Other leukaemias of specified cell type
0.682 0.318 0.000
C93 Monocytic leukaemia
0.682 0.318 0.000
C88 Malignant immunoproliferative diseases
0.682 0.318 0.000
C86 Other specified types of T/NK-cell lymphoma
0.682 0.318 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.682 0.318 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.682 0.318 0.000
G35 Multiple sclerosis
0.680 0.320 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.680 0.320 0.000
E32 Diseases of thymus
0.680 0.320 0.000
E31 Polyglandular dysfunction
0.680 0.320 0.000
E30 Disorders of puberty, not elsewhere classified
0.680 0.320 0.000
E26 Hyperaldosteronism
0.680 0.320 0.000
E25 Adrenogenital disorders
0.680 0.320 0.000
E20 Hypoparathyroidism
0.680 0.320 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.679 0.321 0.000
C71 Malignant neoplasm of brain
0.677 0.323 0.000
C77.4 Inguinal and lower limb lymph nodes
0.677 0.323 0.000
D67 Hereditary factor IX deficiency
0.677 0.323 0.000
D66 Hereditary factor VIII deficiency
0.677 0.323 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.677 0.323 0.000
S06.9 Intracranial injury, unspecified
0.677 0.323 0.000
S06.7 Intracranial injury with prolonged coma
0.677 0.323 0.000
S06.4 Epidural haemorrhage
0.677 0.323 0.000
S06.1 Traumatic cerebral oedema
0.677 0.323 0.000
S06.0 Concussion
0.677 0.323 0.000
G20 Parkinson's disease
0.677 0.323 0.000
W20-W49 Exposure to inanimate mechanical forces
0.676 0.324 0.000
C54 Malignant neoplasm of corpus uteri
0.676 0.324 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.675 0.324 0.000
D74 Methaemoglobinaemia
0.675 0.324 0.000
D73 Diseases of spleen
0.675 0.324 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.675 0.324 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.675 0.324 0.000
I00-I02 Acute rheumatic fever
0.675 0.325 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.674 0.326 0.000
I95.8 Other hypotension
0.674 0.326 0.000
I95.0 Idiopathic hypotension
0.674 0.326 0.000
O45 Premature separation of placenta [abruptio placentae]
0.674 0.326 0.000
O44 Placenta praevia
0.674 0.326 0.000
O41 Other disorders of amniotic fluid and membranes
0.674 0.326 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.674 0.326 0.000
O33 Maternal care for known or suspected disproportion
0.674 0.326 0.000
O31 Complications specific to multiple gestation
0.674 0.326 0.000
E34.9 Endocrine disorder, unspecified
0.673 0.326 0.000
C81 Hodgkin's disease
0.673 0.327 0.000
J69.0 Pneumonitis due to food and vomit
0.673 0.327 0.000
Z34 Supervision of normal pregnancy
0.672 0.328 0.000
J02 Acute pharyngitis
0.672 0.328 0.000
M20 Acquired deformities of fingers and toes
0.672 0.328 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.671 0.329 0.000
C80 Malignant neoplasm without specification of site
0.671 0.329 0.000
M81 Osteoporosis without pathological fracture
0.670 0.330 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.669 0.331 0.000
Z45.8 Adjustment and management of other implanted devices
0.669 0.331 0.000
E13 Other specified diabetes mellitus
0.669 0.331 0.000
D50-D53 Nutritional anaemias
0.668 0.332 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.667 0.332 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.667 0.332 0.000
C32 Malignant neoplasm of larynx
0.667 0.332 0.000
C31 Malignant neoplasm of accessory sinuses
0.667 0.332 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.667 0.332 0.000
C37 Malignant neoplasm of thymus
0.667 0.332 0.000
C33 Malignant neoplasm of trachea
0.667 0.332 0.000
J01 Acute sinusitis
0.666 0.333 0.000
H46 Optic neuritis
0.666 0.333 0.000
V10-V19 Pedal cyclist injured in transport accident
0.665 0.335 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.665 0.335 0.000
A80-A89 Viral infections of the central nervous system
0.665 0.335 0.000
O86 Other puerperal infections
0.665 0.335 0.000
E11.2 With renal complications
0.663 0.337 0.000
G58 Other mononeuropathies
0.663 0.337 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.663 0.337 0.000
E67 Other hyperalimentation
0.662 0.338 0.000
E68 Sequelae of hyperalimentation
0.662 0.338 0.000
E65 Localised adiposity
0.662 0.338 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.662 0.338 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.662 0.338 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.661 0.339 0.000
O30 Multiple gestation
0.661 0.339 0.000
M84 Disorders of continuity of bone
0.661 0.339 0.000
D06 Carcinoma in situ of cervix uteri
0.659 0.341 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
E12 Malnutrition-related diabetes mellitus
0.659 0.341 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.658 0.342 0.000
G96 Other disorders of central nervous system
0.658 0.342 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.658 0.342 0.000
G90 Disorders of autonomic nervous system
0.658 0.342 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.658 0.342 0.000
G92 Toxic encephalopathy
0.658 0.342 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.658 0.342 0.000
Z45.3 Adjustment and management of implanted hearing device
0.658 0.342 0.000
G57 Mononeuropathies of lower limb
0.658 0.342 0.000
S60-S69 Injuries to the wrist and hand
0.658 0.342 0.000
S82.4 Fracture of fibula alone
0.658 0.342 0.000
O26.8 Other specified pregnancy-related conditions
0.657 0.343 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.657 0.343 0.000
C77.9 Lymph node, unspecified
0.657 0.343 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.656 0.344 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.656 0.344 0.000
C69 Malignant neoplasm of eye and adnexa
0.655 0.345 0.000
Q60-Q64 Congenital malformations of the urinary system
0.653 0.347 0.000
R30-R39 Symptoms and signs involving the urinary system
0.653 0.347 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.653 0.347 0.000
S82.30 Fracture of lower end of tibia (closed)
0.652 0.348 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.651 0.349 0.000
H11 Other disorders of conjunctiva
0.651 0.349 0.000
I74 Arterial embolism and thrombosis
0.650 0.350 0.000
E10.9 Without complications
0.650 0.350 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.650 0.350 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.650 0.350 0.000
S00.9 Superficial injury of head, part unspecified
0.650 0.350 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.649 0.351 0.000
M35 Other systemic involvement of connective tissue
0.649 0.351 0.000
E11.4 With neurological complications
0.649 0.351 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.649 0.351 0.000
S02.7 Multiple fractures involving skull and facial bones
0.649 0.351 0.000
S02.6 Fracture of mandible
0.649 0.351 0.000
S02.5 Fracture of tooth
0.649 0.351 0.000
S02.3 Fracture of orbital floor
0.649 0.351 0.000
D61 Other aplastic anaemias
0.648 0.352 0.000
G81.9 Hemiplegia, unspecified
0.648 0.352 0.000
D69.6 Thrombocytopenia, unspecified
0.648 0.352 0.000
D68.2 Hereditary deficiency of other clotting factors
0.648 0.352 0.000
O42.9 Premature rupture of membranes, unspecified
0.648 0.352 0.000
S88 Traumatic amputation of lower leg
0.648 0.352 0.000
S87 Crushing injury of lower leg
0.648 0.352 0.000
S86 Injury of muscle and tendon at lower leg level
0.648 0.352 0.000
S85 Injury of blood vessels at lower leg level
0.648 0.352 0.000
S84 Injury of nerves at lower leg level
0.648 0.352 0.000
M48 Other spondylopathies
0.648 0.352 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.647 0.353 0.000
H02.3 Blepharochalasis
0.647 0.353 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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