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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80008812
log Bayes Factor = 14.3141
Chromosome 19   position 53,500,544  (GRCh37) Explore rs80008812 on Ensembl!
Variant rs80008812 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M20 Acquired deformities of fingers and toes
0.999 0.001 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.997 0.003 0.000
M20.1 Hallux valgus (acquired)
0.995 0.005 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.990 0.010 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.985 0.015 0.000
M25 Other joint disorders, not elsewhere classified
0.983 0.017 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.983 0.017 0.000
R94 Abnormal results of function studies
0.982 0.018 0.000
I20-I25 Ischaemic heart diseases
0.974 0.026 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.974 0.026 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.972 0.028 0.000
E70-E90 Metabolic disorders
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.971 0.029 0.000
Chapter IX Diseases of the circulatory system
0.970 0.030 0.000
M50-M54 Other dorsopathies
0.969 0.031 0.000
R94.5 Abnormal results of liver function studies
0.969 0.031 0.000
E86 Volume depletion
0.967 0.033 0.000
J30-J39 Other diseases of upper respiratory tract
0.966 0.034 0.000
M79.6 Pain in limb
0.965 0.035 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.964 0.036 0.000
C77.0 Lymph nodes of head, face and neck
0.963 0.037 0.000
C79 Secondary malignant neoplasm of other sites
0.962 0.038 0.000
M25.7 Osteophyte
0.960 0.040 0.000
Chapter VIII Diseases of the ear and mastoid process
0.958 0.042 0.000
C15-C26 Malignant neoplasms of digestive organs
0.958 0.042 0.000
M54 Dorsalgia
0.957 0.043 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.957 0.043 0.000
J20-J22 Other acute lower respiratory infections
0.955 0.045 0.000
I20 Angina pectoris
0.952 0.048 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.944 0.056 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.943 0.057 0.000
I22 Subsequent myocardial infarction
0.939 0.061 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.935 0.065 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.929 0.071 0.000
M25.77 Osteophyte (Ankle and foot)
0.929 0.071 0.000
C77.3 Axillary and upper limb lymph nodes
0.928 0.072 0.000
J22 Unspecified acute lower respiratory infection
0.928 0.072 0.000
M54.9 Dorsalgia, unspecified
0.924 0.076 0.000
C51-C58 Malignant neoplasms of female genital organs
0.921 0.079 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.918 0.082 0.000
I20.0 Unstable angina
0.915 0.085 0.000
I25 Chronic ischaemic heart disease
0.913 0.087 0.000
B95-B98 Bacterial, viral and other infectious agents
0.912 0.088 0.000
M20.2 Hallux rigidus
0.911 0.089 0.000
A30-A49 Other bacterial diseases
0.910 0.090 0.000
C25 Malignant neoplasm of pancreas
0.910 0.090 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.909 0.091 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.902 0.098 0.000
M20.3 Other deformity of hallux (acquired)
0.899 0.101 0.000
H65-H75 Diseases of middle ear and mastoid
0.897 0.103 0.000
M79.8 Other specified soft tissue disorders
0.897 0.103 0.000
C92 Myeloid leukaemia
0.896 0.104 0.000
M20.5 Other deformities of toe(s) (acquired)
0.895 0.105 0.000
M54.5 Low back pain
0.894 0.106 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.885 0.115 0.000
J33 Nasal polyp
0.884 0.116 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.880 0.120 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.878 0.122 0.000
E83 Disorders of mineral metabolism
0.877 0.123 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.874 0.126 0.000
C78.0 Secondary malignant neoplasm of lung
0.873 0.127 0.000
R94.3 Abnormal results of cardiovascular function studies
0.873 0.127 0.000
C78.7 Secondary malignant neoplasm of liver
0.868 0.132 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.864 0.136 0.000
M86-M90 Other osteopathies
0.863 0.137 0.000
C92.0 Acute myeloid leukaemia
0.862 0.138 0.000
M25.8 Other specified joint disorders
0.861 0.139 0.000
M24 Other specific joint derangements
0.860 0.140 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.859 0.141 0.000
C77.1 Intrathoracic lymph nodes
0.852 0.148 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.852 0.148 0.000
R79 Other abnormal findings of blood chemistry
0.851 0.149 0.000
I21 Acute myocardial infarction
0.850 0.150 0.000
A41 Other septicaemia
0.849 0.151 0.000
A00-A09 Intestinal infectious diseases
0.849 0.151 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.848 0.152 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.848 0.152 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.848 0.152 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.847 0.153 0.000
Y43 Primarily systemic agents
0.842 0.158 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.841 0.159 0.000
M25.74 Osteophyte (Hand)
0.841 0.159 0.000
B35-B49 Mycoses
0.840 0.160 0.000
M79.64 Pain in limb (Hand)
0.838 0.162 0.000
M79.60 Pain in limb (Multiple sites)
0.836 0.164 0.000
C25.0 Head of pancreas
0.835 0.165 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.832 0.168 0.000
C77.8 Lymph nodes of multiple regions
0.832 0.168 0.000
I20.1 Angina pectoris with documented spasm
0.832 0.168 0.000
J00-J06 Acute upper respiratory infections
0.829 0.171 0.000
C77.2 Intra-abdominal lymph nodes
0.827 0.173 0.000
D00-D09 In situ neoplasms
0.827 0.173 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.825 0.175 0.000
H60-H62 Diseases of external ear
0.824 0.176 0.000
I20.9 Angina pectoris, unspecified
0.824 0.176 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.823 0.177 0.000
M54.1 Radiculopathy
0.823 0.177 0.000
T66-T78 Other and unspecified effects of external causes
0.822 0.178 0.000
D70 Agranulocytosis
0.822 0.178 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.820 0.180 0.000
E87.6 Hypokalaemia
0.819 0.181 0.000
R26 Abnormalities of gait and mobility
0.818 0.182 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.815 0.185 0.000
C56 Malignant neoplasm of ovary
0.815 0.185 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.814 0.186 0.000
C80 Malignant neoplasm without specification of site
0.812 0.188 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.809 0.191 0.000
A41.9 Septicaemia, unspecified
0.809 0.191 0.000
J33.9 Nasal polyp, unspecified
0.804 0.196 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.803 0.197 0.000
M60-M63 Disorders of muscles
0.802 0.198 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.802 0.198 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.802 0.198 0.000
D50-D53 Nutritional anaemias
0.800 0.200 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.799 0.201 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.799 0.201 0.000
M79.2 Neuralgia and neuritis, unspecified
0.798 0.202 0.000
M79.9 Soft tissue disorder, unspecified
0.797 0.203 0.000
M79.62 Pain in limb (Upper arm)
0.797 0.203 0.000
J36 Peritonsillar abscess
0.797 0.203 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.797 0.203 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.794 0.206 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.793 0.207 0.000
C25.9 Pancreas, unspecified
0.792 0.208 0.000
B65-B83 Helminthiases
0.792 0.208 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.789 0.211 0.000
M79.5 Residual foreign body in soft tissue
0.787 0.213 0.000
C79.2 Secondary malignant neoplasm of skin
0.786 0.214 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.784 0.216 0.000
Y43.3 Other antineoplastic drugs
0.779 0.221 0.000
M79.67 Pain in limb (Ankle and foot)
0.777 0.223 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.776 0.224 0.000
C20 Malignant neoplasm of rectum
0.776 0.224 0.000
W20-W49 Exposure to inanimate mechanical forces
0.775 0.225 0.000
C54 Malignant neoplasm of corpus uteri
0.775 0.225 0.000
C16 Malignant neoplasm of stomach
0.773 0.227 0.000
E87.5 Hyperkalaemia
0.772 0.228 0.000
H71 Cholesteatoma of middle ear
0.771 0.229 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.770 0.230 0.000
W50-W64 Exposure to animate mechanical forces
0.770 0.230 0.000
H73 Other disorders of tympanic membrane
0.769 0.231 0.000
J39 Other diseases of upper respiratory tract
0.769 0.231 0.000
M45-M49 Spondylopathies
0.767 0.233 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.767 0.233 0.000
M54.56 Low back pain (Lumbar region)
0.765 0.235 0.000
M79.61 Pain in limb (Shoulder region)
0.764 0.236 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.237 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.763 0.237 0.000
J38.7 Other diseases of larynx
0.763 0.237 0.000
I05-I09 Chronic rheumatic heart diseases
0.762 0.238 0.000
I25.5 Ischaemic cardiomyopathy
0.762 0.238 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.762 0.238 0.000
E83.4 Disorders of magnesium metabolism
0.761 0.239 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.761 0.239 0.000
J38.0 Paralysis of vocal cords and larynx
0.761 0.239 0.000
C45 Mesothelioma
0.759 0.241 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.759 0.241 0.000
S10-S19 Injuries to the neck
0.759 0.241 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.758 0.242 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.758 0.242 0.000
M54.50 Low back pain (Multiple sites in spine)
0.757 0.243 0.000
I22.8 Subsequent myocardial infarction of other sites
0.757 0.243 0.000
J38.3 Other diseases of vocal cords
0.757 0.243 0.000
S20-S29 Injuries to the thorax
0.756 0.244 0.000
M79.1 Myalgia
0.756 0.244 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.754 0.246 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.753 0.247 0.000
R71 Abnormality of red blood cells
0.753 0.247 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.751 0.249 0.000
H61 Other disorders of external ear
0.751 0.249 0.000
V80-V89 Other land transport accidents
0.750 0.250 0.000
J60-J70 Lung diseases due to external agents
0.750 0.250 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.749 0.251 0.000
M77 Other enthesopathies
0.749 0.251 0.000
J32 Chronic sinusitis
0.749 0.251 0.000
C91 Lymphoid leukaemia
0.748 0.252 0.000
M25.84 Other specified joint disorders (Hand)
0.747 0.253 0.000
M79.69 Pain in limb (Site unspecified)
0.746 0.254 0.000
T78 Adverse effects, not elsewhere classified
0.746 0.254 0.000
Chapter XXI Factors influencing health status and contact with health services
0.745 0.255 0.000
J38.4 Oedema of larynx
0.744 0.256 0.000
J09-J18 Influenza and pneumonia
0.743 0.257 0.000
C32 Malignant neoplasm of larynx
0.742 0.258 0.000
X60-X84 Intentional self-harm
0.742 0.258 0.000
C34 Malignant neoplasm of bronchus and lung
0.741 0.259 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.741 0.259 0.000
S60-S69 Injuries to the wrist and hand
0.739 0.261 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.738 0.262 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.735 0.264 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.735 0.265 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.735 0.265 0.000
M40-M43 Deforming dorsopathies
0.735 0.265 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.735 0.265 0.000
J33.0 Polyp of nasal cavity
0.734 0.266 0.000
V10-V19 Pedal cyclist injured in transport accident
0.734 0.266 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.733 0.267 0.000
M25.71 Osteophyte (Shoulder region)
0.733 0.267 0.000
S90-S99 Injuries to the ankle and foot
0.733 0.267 0.000
R20 Disturbances of skin sensation
0.732 0.268 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.732 0.268 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.732 0.268 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.732 0.268 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.730 0.270 0.000
M88 Paget's disease of bone [osteitis deformans]
0.729 0.271 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.728 0.272 0.000
M54.55 Low back pain (Thoracolumbar region)
0.728 0.272 0.000
R74 Abnormal serum enzyme levels
0.727 0.273 0.000
J20 Acute bronchitis
0.726 0.274 0.000
R79.0 Abnormal level of blood mineral
0.726 0.274 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.726 0.274 0.000
M24.1 Other articular cartilage disorders
0.726 0.274 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.725 0.275 0.000
M25.72 Osteophyte (Upper arm)
0.725 0.275 0.000
J31.0 Chronic rhinitis
0.724 0.276 0.000
I25.1 Atherosclerotic heart disease
0.724 0.276 0.000
D75 Other diseases of blood and blood-forming organs
0.722 0.277 0.000
D51 Vitamin B12 deficiency anaemia
0.722 0.278 0.000
M91-M94 Chondropathies
0.722 0.278 0.000
A46 Erysipelas
0.721 0.279 0.000
H80-H83 Diseases of inner ear
0.721 0.279 0.000
M20.4 Other hammer toe(s) (acquired)
0.720 0.280 0.000
Y44 Agents primarily affecting blood constituents
0.719 0.281 0.000
C18 Malignant neoplasm of colon
0.719 0.281 0.000
M00-M03 Infectious arthropathies
0.718 0.282 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.717 0.283 0.000
E83.1 Disorders of iron metabolism
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M25.3 Other instability of joint
0.716 0.284 0.000
I21.4 Acute subendocardial myocardial infarction
0.716 0.284 0.000
Y40 Systemic antibiotics
0.716 0.284 0.000
B35 Dermatophytosis
0.716 0.284 0.000
I24 Other acute ischaemic heart diseases
0.715 0.285 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.715 0.285 0.000
H74 Other disorders of middle ear and mastoid
0.714 0.286 0.000
H65 Nonsuppurative otitis media
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
C71 Malignant neoplasm of brain
0.710 0.290 0.000
B99-B99 Other infectious diseases
0.710 0.290 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.709 0.290 0.000
A80-A89 Viral infections of the central nervous system
0.709 0.291 0.000
C90.0 Multiple myeloma
0.709 0.291 0.000
M54.57 Low back pain (Lumbosacral region)
0.707 0.293 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.707 0.293 0.000
M76 Enthesopathies of lower limb, excluding foot
0.706 0.293 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.293 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.706 0.294 0.000
M79.88 Other specified soft tissue disorders (Other)
0.706 0.294 0.000
T31 Burns classified according to extent of body surface involved
0.706 0.294 0.000
B44 Aspergillosis
0.705 0.295 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.704 0.295 0.000
M79.3 Panniculitis, unspecified
0.704 0.295 0.000
M25.9 Joint disorder, unspecified
0.704 0.295 0.000
M25.2 Flail joint
0.704 0.295 0.000
M25.1 Fistula of joint
0.704 0.295 0.000
M25.0 Haemarthrosis
0.704 0.295 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.704 0.296 0.000
R94.7 Abnormal results of other endocrine function studies
0.704 0.296 0.000
R94.6 Abnormal results of thyroid function studies
0.704 0.296 0.000
R94.4 Abnormal results of kidney function studies
0.704 0.296 0.000
R94.2 Abnormal results of pulmonary function studies
0.704 0.296 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.704 0.296 0.000
R94.0 Abnormal results of function studies of central nervous system
0.704 0.296 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.704 0.296 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.703 0.297 0.000
M34 Systemic sclerosis
0.703 0.297 0.000
H72 Perforation of tympanic membrane
0.703 0.297 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.702 0.298 0.000
R23 Other skin changes
0.701 0.299 0.000
E87.2 Acidosis
0.700 0.299 0.000
M21 Other acquired deformities of limbs
0.700 0.300 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.699 0.301 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.698 0.301 0.000
I23 Certain current complications following acute myocardial infarction
0.698 0.302 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.698 0.302 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.697 0.303 0.000
E85 Amyloidosis
0.697 0.303 0.000
E84 Cystic fibrosis
0.697 0.303 0.000
E79 Disorders of purine and pyrimidine metabolism
0.697 0.303 0.000
E77 Disorders of glycoprotein metabolism
0.697 0.303 0.000
E76 Disorders of glycosaminoglycan metabolism
0.697 0.303 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.697 0.303 0.000
E74 Other disorders of carbohydrate metabolism
0.697 0.303 0.000
E73 Lactose intolerance
0.697 0.303 0.000
E72 Other disorders of amino-acid metabolism
0.697 0.303 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.697 0.303 0.000
E70 Disorders of aromatic amino-acid metabolism
0.697 0.303 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.697 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
Y00-Y09 Assault
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.304 0.000
X50-X57 Overexertion, travel and privation
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V20-V29 Motorcycle rider injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
D06 Carcinoma in situ of cervix uteri
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.696 0.304 0.000
M54.16 Radiculopathy (Lumbar region)
0.696 0.304 0.000
B15-B19 Viral hepatitis
0.694 0.305 0.000
M54.6 Pain in thoracic spine
0.694 0.306 0.000
E88 Other metabolic disorders
0.694 0.306 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.694 0.306 0.000
T78.2 Anaphylactic shock, unspecified
0.694 0.306 0.000
T79-T79 Certain early complications of trauma
0.694 0.306 0.000
J37 Chronic laryngitis and laryngotracheitis
0.693 0.307 0.000
M79.68 Pain in limb (Other)
0.692 0.308 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.691 0.309 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.691 0.309 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.691 0.309 0.000
C79.6 Secondary malignant neoplasm of ovary
0.690 0.310 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.690 0.310 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.690 0.310 0.000
M25.79 Osteophyte (Site unspecified)
0.688 0.312 0.000
M25.73 Osteophyte (Forearm)
0.688 0.312 0.000
M25.70 Osteophyte (Multiple sites)
0.688 0.312 0.000
R21 Rash and other nonspecific skin eruption
0.688 0.312 0.000
Y52 Agents primarily affecting the cardiovascular system
0.687 0.312 0.000
C21 Malignant neoplasm of anus and anal canal
0.687 0.313 0.000
C17 Malignant neoplasm of small intestine
0.687 0.313 0.000
C23 Malignant neoplasm of gallbladder
0.687 0.313 0.000
M54.8 Other dorsalgia
0.686 0.313 0.000
M54.0 Panniculitis affecting regions of neck and back
0.686 0.313 0.000
Chapter XXII Codes for special purposes
0.685 0.314 0.000
C77.9 Lymph node, unspecified
0.685 0.315 0.000
M90 Osteopathies in diseases classified elsewhere
0.685 0.315 0.000
J21 Acute bronchiolitis
0.685 0.315 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.684 0.316 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.682 0.318 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.682 0.318 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.681 0.319 0.000
Y95 Nosocomial condition
0.680 0.320 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.680 0.320 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.678 0.321 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.678 0.322 0.000
E40-E46 Malnutrition
0.678 0.322 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.677 0.323 0.000
M50 Cervical disk disorders
0.677 0.323 0.000
M54.4 Lumbago with sciatica
0.677 0.323 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.677 0.323 0.000
C95 Leukaemia of unspecified cell type
0.677 0.323 0.000
C94 Other leukaemias of specified cell type
0.677 0.323 0.000
C93 Monocytic leukaemia
0.677 0.323 0.000
C88 Malignant immunoproliferative diseases
0.677 0.323 0.000
C86 Other specified types of T/NK-cell lymphoma
0.677 0.323 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.677 0.323 0.000
C81 Hodgkin's disease
0.677 0.323 0.000
I05 Rheumatic mitral valve diseases
0.677 0.323 0.000
R77 Other abnormalities of plasma proteins
0.676 0.324 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.676 0.324 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.676 0.324 0.000
C77.4 Inguinal and lower limb lymph nodes
0.675 0.325 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.674 0.326 0.000
M71 Other bursopathies
0.673 0.326 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.673 0.327 0.000
J04 Acute laryngitis and tracheitis
0.673 0.327 0.000
D55-D59 Haemolytic anaemias
0.671 0.329 0.000
C54.1 Endometrium
0.670 0.330 0.000
M79.0 Rheumatism, unspecified
0.670 0.330 0.000
M24.2 Disorder of ligament
0.669 0.330 0.000
R27 Other lack of coordination
0.669 0.331 0.000
R26.3 Immobility
0.669 0.331 0.000
M79.66 Pain in limb (Lower leg)
0.667 0.333 0.000
T33-T35 Frostbite
0.666 0.334 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.666 0.334 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.666 0.334 0.000
T00-T07 Injuries involving multiple body regions
0.666 0.334 0.000
M80-M85 Disorders of bone density and structure
0.666 0.334 0.000
M53 Other dorsopathies, not elsewhere classified
0.666 0.334 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.666 0.334 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.664 0.336 0.000
I21.9 Acute myocardial infarction, unspecified
0.664 0.336 0.000
M25.78 Osteophyte (Other)
0.663 0.337 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.663 0.337 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.662 0.337 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.662 0.337 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.662 0.337 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.662 0.337 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.662 0.337 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.662 0.337 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.662 0.337 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.662 0.337 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.662 0.337 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.662 0.338 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.661 0.338 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.661 0.339 0.000
M62 Other disorders of muscle
0.661 0.339 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.661 0.339 0.000
C51 Malignant neoplasm of vulva
0.661 0.339 0.000
C58 Malignant neoplasm of placenta
0.661 0.339 0.000
C52 Malignant neoplasm of vagina
0.661 0.339 0.000
R47-R49 Symptoms and signs involving speech and voice
0.659 0.341 0.000
M25.4 Effusion of joint
0.659 0.341 0.000
Y59 Other and unspecified vaccines and biological substances
0.658 0.342 0.000
Y58 Bacterial vaccines
0.658 0.342 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.658 0.342 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.658 0.342 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.658 0.342 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.658 0.342 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.658 0.342 0.000
Y48 Anaesthetics and therapeutic gases
0.658 0.342 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.658 0.342 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.658 0.342 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.658 0.342 0.000
C69 Malignant neoplasm of eye and adnexa
0.658 0.342 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.657 0.343 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.657 0.343 0.000
C77.5 Intrapelvic lymph nodes
0.657 0.343 0.000
C80.9 Malignant neoplasm, unspecified
0.656 0.344 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.656 0.344 0.000
A04 Other bacterial intestinal infections
0.656 0.344 0.000
H61.2 Impacted cerumen
0.655 0.345 0.000
C53 Malignant neoplasm of cervix uteri
0.655 0.345 0.000
I25.6 Silent myocardial ischaemia
0.655 0.345 0.000
I25.4 Coronary artery aneurysm
0.655 0.345 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.655 0.345 0.000
C15 Malignant neoplasm of oesophagus
0.653 0.347 0.000
A48 Other bacterial diseases, not elsewhere classified
0.652 0.347 0.000
A44 Bartonellosis
0.652 0.347 0.000
A43 Nocardiosis
0.652 0.347 0.000
A42 Actinomycosis
0.652 0.347 0.000
A40 Streptococcal septicaemia
0.652 0.347 0.000
A39 Meningococcal infection
0.652 0.347 0.000
A37 Whooping cough
0.652 0.347 0.000
A36 Diphtheria
0.652 0.347 0.000
A32 Listeriosis
0.652 0.347 0.000
A31 Infection due to other mycobacteria
0.652 0.347 0.000
A30 Leprosy [Hansen's disease]
0.652 0.347 0.000
A38 Scarlet fever
0.652 0.347 0.000
A35 Other tetanus
0.652 0.347 0.000
A34 Obstetrical tetanus
0.652 0.347 0.000
A33 Tetanus neonatorum
0.652 0.347 0.000
C25.8 Overlapping lesion of pancreas
0.652 0.347 0.000
C25.7 Other parts of pancreas
0.652 0.347 0.000
C25.4 Endocrine pancreas
0.652 0.347 0.000
C25.3 Pancreatic duct
0.652 0.347 0.000
C25.2 Tail of pancreas
0.652 0.347 0.000
C25.1 Body of pancreas
0.652 0.347 0.000
M89 Other disorders of bone
0.652 0.348 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.652 0.348 0.000
E87.4 Mixed disorder of acid-base balance
0.651 0.348 0.000
B80 Enterobiasis
0.650 0.350 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.650 0.350 0.000
J00 Acute nasopharyngitis [common cold]
0.648 0.352 0.000
H90-H95 Other disorders of ear
0.648 0.352 0.000
M79.54 Residual foreign body in soft tissue (Hand)
0.647 0.352 0.000
J38.6 Stenosis of larynx
0.647 0.353 0.000
J38.5 Laryngeal spasm
0.647 0.353 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.647 0.353 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.646 0.353 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.646 0.354 0.000
M20.0 Deformity of finger(s)
0.645 0.354 0.000
E83.3 Disorders of phosphorus metabolism
0.645 0.355 0.000
C18.9 Colon, unspecified
0.644 0.356 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.643 0.356 0.000
H70 Mastoiditis and related conditions
0.643 0.356 0.000
H69 Other disorders of Eustachian tube
0.643 0.356 0.000
H68 Eustachian salpingitis and obstruction
0.643 0.356 0.000
H67 Otitis media in diseases classified elsewhere
0.643 0.356 0.000
M72 Fibroblastic disorders
0.643 0.356 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.643 0.357 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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