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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80106349
log Bayes Factor = 14.628
Chromosome 1   position 72,608,658  (GRCh37) Explore rs80106349 on Ensembl!
Variant rs80106349 is part of Cluster X0001

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
K55-K64 Other diseases of intestines
0.997 0.003 0.000
K57 Diverticular disease of intestine
0.996 0.004 0.000
Chapter XI Diseases of the digestive system
0.996 0.004 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.990 0.010 0.000
M05-M14 Inflammatory polyarthropathies
0.990 0.010 0.000
J40-J47 Chronic lower respiratory diseases
0.987 0.013 0.000
Z96 Presence of other functional implants
0.987 0.013 0.000
J90-J94 Other diseases of pleura
0.986 0.014 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.982 0.018 0.000
M50-M54 Other dorsopathies
0.981 0.019 0.000
M06 Other rheumatoid arthritis
0.980 0.020 0.000
Chapter VIII Diseases of the ear and mastoid process
0.978 0.022 0.000
J90 Pleural effusion, not elsewhere classified
0.977 0.023 0.000
Z96.6 Presence of orthopaedic joint implants
0.974 0.026 0.000
J44 Other chronic obstructive pulmonary disease
0.970 0.030 0.000
M06.9 Rheumatoid arthritis, unspecified
0.968 0.032 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.962 0.038 0.000
H65-H75 Diseases of middle ear and mastoid
0.958 0.042 0.000
Z87 Personal history of other diseases and conditions
0.956 0.044 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.954 0.046 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.954 0.046 0.000
Y43 Primarily systemic agents
0.953 0.047 0.000
M80-M85 Disorders of bone density and structure
0.950 0.050 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.945 0.055 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.942 0.058 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.942 0.058 0.000
M54 Dorsalgia
0.939 0.061 0.000
Z83 Family history of other specific disorders
0.934 0.066 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.928 0.072 0.000
K58 Irritable bowel syndrome
0.924 0.076 0.000
Y43.3 Other antineoplastic drugs
0.921 0.079 0.000
J47 Bronchiectasis
0.920 0.080 0.000
M79.6 Pain in limb
0.920 0.080 0.000
G30-G32 Other degenerative diseases of the nervous system
0.918 0.082 0.000
F30-F39 Mood [affective] disorders
0.914 0.085 0.000
F10.1 Harmful use
0.914 0.086 0.000
M50 Cervical disk disorders
0.913 0.087 0.000
Chapter II Neoplasms
0.913 0.087 0.000
K61 Abscess of anal and rectal regions
0.912 0.088 0.000
K63 Other diseases of intestine
0.910 0.090 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.910 0.090 0.000
J09-J18 Influenza and pneumonia
0.909 0.091 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.906 0.094 0.000
M45-M49 Spondylopathies
0.905 0.095 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.898 0.102 0.000
Z87.1 Personal history of diseases of the digestive system
0.896 0.104 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.896 0.104 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.896 0.104 0.000
Z96.8 Presence of other specified functional implants
0.894 0.106 0.000
F10.2 Dependence syndrome
0.893 0.107 0.000
H66 Suppurative and unspecified otitis media
0.892 0.108 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.892 0.108 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.892 0.108 0.000
Z93 Artificial opening status
0.889 0.111 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.885 0.115 0.000
Chapter VII Diseases of the eye and adnexa
0.877 0.123 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.874 0.126 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.870 0.130 0.000
G90-G99 Other disorders of the nervous system
0.870 0.130 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.870 0.130 0.000
Z02 Examination and encounter for administrative purposes
0.870 0.130 0.000
H60-H62 Diseases of external ear
0.870 0.130 0.000
F17.2 Dependence syndrome
0.869 0.131 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.866 0.134 0.000
M79.8 Other specified soft tissue disorders
0.865 0.135 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.865 0.135 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.860 0.140 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.860 0.140 0.000
F32 Depressive episode
0.857 0.143 0.000
M81 Osteoporosis without pathological fracture
0.855 0.145 0.000
M54.3 Sciatica
0.853 0.146 0.000
M10 Gout
0.848 0.151 0.000
H66.9 Otitis media, unspecified
0.848 0.152 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.847 0.153 0.000
K63.5 Polyp of colon
0.846 0.154 0.000
Z97 Presence of other devices
0.845 0.155 0.000
F32.9 Depressive episode, unspecified
0.844 0.156 0.000
Z02.8 Other examinations for administrative purposes
0.841 0.159 0.000
K07 Dentofacial anomalies [including malocclusion]
0.838 0.162 0.000
F17.1 Harmful use
0.833 0.167 0.000
Z50 Care involving use of rehabilitation procedures
0.833 0.167 0.000
W00-W19 Falls
0.823 0.177 0.000
M05 Seropositive rheumatoid arthritis
0.822 0.178 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.821 0.179 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.821 0.179 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.820 0.180 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.818 0.182 0.000
J95-J99 Other diseases of the respiratory system
0.817 0.183 0.000
M47 Spondylosis
0.816 0.184 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.816 0.184 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.815 0.185 0.000
J18 Pneumonia, organism unspecified
0.815 0.185 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.812 0.188 0.000
K61.0 Anal abscess
0.812 0.188 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.811 0.189 0.000
M06.0 Seronegative rheumatoid arthritis
0.811 0.189 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.809 0.191 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.809 0.191 0.000
C64-C68 Malignant neoplasms of urinary tract
0.809 0.191 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.808 0.192 0.000
H65 Nonsuppurative otitis media
0.808 0.192 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.805 0.195 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.803 0.197 0.000
Z83.7 Family history of diseases of the digestive system
0.801 0.199 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.799 0.201 0.000
M50.1 Cervical disk disorder with radiculopathy
0.799 0.201 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.797 0.203 0.000
Z81 Family history of mental and behavioural disorders
0.796 0.204 0.000
M84 Disorders of continuity of bone
0.795 0.205 0.000
H61 Other disorders of external ear
0.793 0.207 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.793 0.207 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.792 0.207 0.000
M80 Osteoporosis with pathological fracture
0.791 0.209 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.791 0.209 0.000
Z83.5 Family history of eye and ear disorders
0.791 0.209 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.790 0.210 0.000
M79.60 Pain in limb (Multiple sites)
0.790 0.210 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.787 0.213 0.000
M81.9 Osteoporosis, unspecified
0.787 0.213 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.786 0.214 0.000
F80-F89 Disorders of psychological development
0.786 0.214 0.000
J86 Pyothorax
0.785 0.215 0.000
Y45.0 Opioids and related analgesics
0.783 0.217 0.000
M47.9 Spondylosis, unspecified
0.780 0.220 0.000
V40-V49 Car occupant injured in transport accident
0.777 0.222 0.000
G81 Hemiplegia
0.777 0.223 0.000
M77 Other enthesopathies
0.777 0.223 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.776 0.223 0.000
H74 Other disorders of middle ear and mastoid
0.774 0.226 0.000
H71 Cholesteatoma of middle ear
0.773 0.227 0.000
J94 Other pleural conditions
0.773 0.227 0.000
Z94 Transplanted organ and tissue status
0.772 0.228 0.000
M54.9 Dorsalgia, unspecified
0.770 0.230 0.000
M54.5 Low back pain
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.768 0.232 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.767 0.233 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.767 0.233 0.000
Z74 Problems related to care-provider dependency
0.764 0.235 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.764 0.236 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.763 0.237 0.000
D00-D09 In situ neoplasms
0.763 0.237 0.000
K07.3 Anomalies of tooth position
0.762 0.238 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.762 0.238 0.000
M50.0 Cervical disk disorder with myelopathy
0.761 0.239 0.000
M50.2 Other cervical disk displacement
0.761 0.239 0.000
J91 Pleural effusion in conditions classified elsewhere
0.760 0.240 0.000
Z83.3 Family history of diabetes mellitus
0.760 0.240 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.760 0.240 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.759 0.241 0.000
Z12 Special screening examination for neoplasms
0.758 0.242 0.000
M71 Other bursopathies
0.758 0.242 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.758 0.242 0.000
Y43.4 Immunosuppressive agents
0.758 0.242 0.000
K14 Diseases of tongue
0.756 0.244 0.000
K61.3 Ischiorectal abscess
0.755 0.245 0.000
J93 Pneumothorax
0.754 0.246 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.754 0.246 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.753 0.247 0.000
M54.39 Sciatica (Site unspecified)
0.753 0.247 0.000
Z86 Personal history of certain other diseases
0.752 0.248 0.000
H72 Perforation of tympanic membrane
0.752 0.248 0.000
Z93.1 Gastrostomy status
0.751 0.249 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.751 0.249 0.000
G95 Other diseases of spinal cord
0.749 0.251 0.000
H30-H36 Disorders of choroid and retina
0.748 0.252 0.000
M10.9 Gout, unspecified
0.747 0.253 0.000
V80-V89 Other land transport accidents
0.747 0.253 0.000
Z49 Care involving dialysis
0.747 0.253 0.000
Z86.0 Personal history of other neoplasms
0.744 0.256 0.000
K56.6 Other and unspecified intestinal obstruction
0.744 0.256 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.743 0.257 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.743 0.257 0.000
J46 Status asthmaticus
0.742 0.258 0.000
K63.2 Fistula of intestine
0.742 0.258 0.000
H25-H28 Disorders of lens
0.741 0.259 0.000
M79.1 Myalgia
0.741 0.259 0.000
K70-K77 Diseases of liver
0.739 0.261 0.000
Z89 Acquired absence of limb
0.738 0.262 0.000
Chapter XXII Codes for special purposes
0.738 0.262 0.000
M45 Ankylosing spondylitis
0.737 0.263 0.000
G20-G26 Extrapyramidal and movement disorders
0.736 0.264 0.000
C67 Malignant neoplasm of bladder
0.736 0.264 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.735 0.265 0.000
F33 Recurrent depressive disorder
0.735 0.265 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.735 0.265 0.000
Y52 Agents primarily affecting the cardiovascular system
0.734 0.266 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.734 0.266 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.734 0.266 0.000
Z50.2 Alcohol rehabilitation
0.733 0.267 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.731 0.269 0.000
M79.64 Pain in limb (Hand)
0.731 0.269 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.730 0.270 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.730 0.270 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.730 0.270 0.000
Z48 Other surgical follow-up care
0.730 0.270 0.000
G58 Other mononeuropathies
0.729 0.271 0.000
Z93.0 Tracheostomy status
0.729 0.271 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.275 0.000
Z96.1 Presence of intraocular lens
0.725 0.275 0.000
J43 Emphysema
0.723 0.277 0.000
Z13 Special screening examination for other diseases and disorders
0.723 0.277 0.000
M40-M43 Deforming dorsopathies
0.722 0.277 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.722 0.278 0.000
F99-F99 Unspecified mental disorder
0.722 0.278 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.721 0.279 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.721 0.279 0.000
J86.9 Pyothorax without fistula
0.721 0.279 0.000
J40 Bronchitis, not specified as acute or chronic
0.721 0.279 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
K11 Diseases of salivary glands
0.716 0.284 0.000
K63.8 Other specified diseases of intestine
0.716 0.284 0.000
J18.0 Bronchopneumonia, unspecified
0.716 0.284 0.000
Z99.8 Dependence on other enabling machines and devices
0.716 0.284 0.000
K90-K93 Other diseases of the digestive system
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.715 0.285 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.714 0.285 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.714 0.285 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.714 0.285 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.714 0.286 0.000
G81.9 Hemiplegia, unspecified
0.714 0.286 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
Y57 Other and unspecified drugs and medicaments
0.711 0.289 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.710 0.290 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.710 0.290 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.710 0.290 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.710 0.290 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.710 0.290 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.710 0.290 0.000
F11 Mental and behavioural disorders due to use of opioids
0.710 0.290 0.000
M14 Arthropathies in other diseases classified elsewhere
0.710 0.290 0.000
M12 Other specific arthropathies
0.710 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.710 0.290 0.000
M08 Juvenile arthritis
0.710 0.290 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.708 0.292 0.000
J41 Simple and mucopurulent chronic bronchitis
0.708 0.292 0.000
J42 Unspecified chronic bronchitis
0.708 0.292 0.000
J98 Other respiratory disorders
0.708 0.292 0.000
Z96.9 Presence of functional implant, unspecified
0.707 0.293 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.707 0.293 0.000
Z96.4 Presence of endocrine implants
0.707 0.293 0.000
Z96.3 Presence of artificial larynx
0.707 0.293 0.000
Z96.2 Presence of otological and audiological implants
0.707 0.293 0.000
H55-H59 Other disorders of eye and adnexa
0.707 0.293 0.000
Y59 Other and unspecified vaccines and biological substances
0.707 0.293 0.000
Y58 Bacterial vaccines
0.707 0.293 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.707 0.293 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.707 0.293 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.707 0.293 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
Y48 Anaesthetics and therapeutic gases
0.707 0.293 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.707 0.293 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.707 0.293 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.705 0.295 0.000
M76 Enthesopathies of lower limb, excluding foot
0.704 0.296 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.704 0.296 0.000
C85.1 B-cell lymphoma, unspecified
0.703 0.297 0.000
M06.8 Other specified rheumatoid arthritis
0.702 0.297 0.000
M06.4 Inflammatory polyarthropathy
0.702 0.297 0.000
M06.3 Rheumatoid nodule
0.702 0.297 0.000
M06.2 Rheumatoid bursitis
0.702 0.297 0.000
M06.1 Adult-onset Still's disease
0.702 0.297 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.702 0.298 0.000
C81 Hodgkin's disease
0.701 0.298 0.000
M65-M68 Disorders of synovium and tendon
0.701 0.299 0.000
H90-H95 Other disorders of ear
0.701 0.299 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.701 0.299 0.000
G93 Other disorders of brain
0.701 0.299 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.700 0.300 0.000
K63.1 Perforation of intestine (nontraumatic)
0.700 0.300 0.000
G31.2 Degeneration of nervous system due to alcohol
0.700 0.300 0.000
E00-E07 Disorders of thyroid gland
0.700 0.300 0.000
O60-O75 Complications of labour and delivery
0.699 0.301 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.698 0.302 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.698 0.302 0.000
Y42.7 Androgens and anabolic congeners
0.698 0.302 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.698 0.302 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.697 0.303 0.000
Z96.7 Presence of other bone and tendon implants
0.697 0.303 0.000
Z51 Other medical care
0.696 0.304 0.000
M79.0 Rheumatism, unspecified
0.696 0.304 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.695 0.304 0.000
M79.67 Pain in limb (Ankle and foot)
0.695 0.305 0.000
O36 Maternal care for other known or suspected foetal problems
0.695 0.305 0.000
Z47 Other orthopaedic follow-up care
0.695 0.305 0.000
K09 Cysts of oral region, not elsewhere classified
0.694 0.306 0.000
M54.2 Cervicalgia
0.694 0.306 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.694 0.306 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.694 0.306 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.694 0.306 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.694 0.306 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.694 0.306 0.000
Z93.2 Ileostomy status
0.694 0.306 0.000
Z51.2 Other chemotherapy
0.693 0.307 0.000
Z75 Problems related to medical facilities and other health care
0.692 0.308 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.692 0.308 0.000
H61.0 Perichondritis of external ear
0.691 0.309 0.000
Z97.0 Presence of artificial eye
0.691 0.309 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.690 0.309 0.000
M54.6 Pain in thoracic spine
0.690 0.310 0.000
W19 Unspecified fall
0.690 0.310 0.000
M79.9 Soft tissue disorder, unspecified
0.690 0.310 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.690 0.310 0.000
M79.3 Panniculitis, unspecified
0.690 0.310 0.000
M79.2 Neuralgia and neuritis, unspecified
0.690 0.310 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.689 0.311 0.000
S10-S19 Injuries to the neck
0.689 0.311 0.000
O85-O92 Complications predominantly related to the puerperium
0.689 0.311 0.000
S70-S79 Injuries to the hip and thigh
0.687 0.312 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.687 0.313 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.687 0.313 0.000
H70 Mastoiditis and related conditions
0.687 0.313 0.000
H68 Eustachian salpingitis and obstruction
0.687 0.313 0.000
H67 Otitis media in diseases classified elsewhere
0.687 0.313 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.685 0.314 0.000
V20-V29 Motorcycle rider injured in transport accident
0.685 0.315 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.685 0.315 0.000
K07.6 Temporomandibular joint disorders
0.685 0.315 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.685 0.315 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.684 0.316 0.000
M53 Other dorsopathies, not elsewhere classified
0.684 0.316 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.684 0.316 0.000
G52 Disorders of other cranial nerves
0.684 0.316 0.000
F10.9 Unspecified mental and behavioural disorder
0.684 0.316 0.000
F10.8 Other mental and behavioural disorders
0.684 0.316 0.000
F10.7 Residual and late-onset psychotic disorder
0.684 0.316 0.000
F10.6 Amnesic syndrome
0.684 0.316 0.000
F10.5 Psychotic disorder
0.684 0.316 0.000
F10.4 Withdrawal state with delirium
0.684 0.316 0.000
M54.4 Lumbago with sciatica
0.684 0.316 0.000
Y43.9 Primarily systemic agent, unspecified
0.683 0.316 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.683 0.316 0.000
Y43.6 Enzymes, not elsewhere classified
0.683 0.316 0.000
Y43.5 Acidifying and alkalising agents
0.683 0.316 0.000
Y43.2 Antineoplastic natural products
0.683 0.316 0.000
Y43.1 Antineoplastic antimetabolites
0.683 0.316 0.000
Y43.0 Antiallergic and antiemetic drugs
0.683 0.316 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.683 0.317 0.000
K00 Disorders of tooth development and eruption
0.683 0.317 0.000
G57 Mononeuropathies of lower limb
0.682 0.318 0.000
K10 Other diseases of jaws
0.682 0.318 0.000
M83 Adult osteomalacia
0.681 0.319 0.000
M82 Osteoporosis in diseases classified elsewhere
0.681 0.319 0.000
Y45.2 Propionic acid derivatives
0.680 0.320 0.000
K02 Dental caries
0.680 0.320 0.000
G70-G73 Diseases of myoneural junction and muscle
0.680 0.320 0.000
K14.8 Other diseases of tongue
0.680 0.320 0.000
M54.59 Low back pain (Site unspecified)
0.679 0.321 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.679 0.321 0.000
F17.9 Unspecified mental and behavioural disorder
0.678 0.322 0.000
F17.8 Other mental and behavioural disorders
0.678 0.322 0.000
F17.7 Residual and late-onset psychotic disorder
0.678 0.322 0.000
F17.6 Amnesic syndrome
0.678 0.322 0.000
F17.5 Psychotic disorder
0.678 0.322 0.000
F17.4 Withdrawal state with delirium
0.678 0.322 0.000
F17.3 Withdrawal state
0.678 0.322 0.000
F17.0 Acute intoxication
0.678 0.322 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.677 0.323 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.677 0.323 0.000
H69 Other disorders of Eustachian tube
0.677 0.323 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.676 0.323 0.000
G30 Alzheimer's disease
0.676 0.324 0.000
M54.36 Sciatica (Lumbar region)
0.676 0.324 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.676 0.324 0.000
Y40 Systemic antibiotics
0.675 0.325 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.675 0.325 0.000
Z74.0 Reduced mobility
0.674 0.326 0.000
M54.8 Other dorsalgia
0.673 0.327 0.000
M54.0 Panniculitis affecting regions of neck and back
0.673 0.327 0.000
M11 Other crystal arthropathies
0.673 0.327 0.000
X60-X84 Intentional self-harm
0.673 0.327 0.000
K56.2 Volvulus
0.673 0.327 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.673 0.327 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.672 0.328 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.672 0.328 0.000
Z83.6 Family history of diseases of the respiratory system
0.670 0.330 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.670 0.330 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.670 0.330 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.670 0.330 0.000
Y44 Agents primarily affecting blood constituents
0.670 0.330 0.000
C90.0 Multiple myeloma
0.670 0.330 0.000
K12 Stomatitis and related lesions
0.668 0.332 0.000
M79.5 Residual foreign body in soft tissue
0.668 0.332 0.000
E05.9 Thyrotoxicosis, unspecified
0.668 0.332 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.668 0.332 0.000
J14 Pneumonia due to Haemophilus influenzae
0.667 0.333 0.000
G54 Nerve root and plexus disorders
0.665 0.335 0.000
M10.99 Gout, unspecified (Site unspecified)
0.665 0.335 0.000
M07 Psoriatic and enteropathic arthropathies
0.663 0.336 0.000
J20-J22 Other acute lower respiratory infections
0.662 0.338 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.661 0.339 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.661 0.339 0.000
M79.68 Pain in limb (Other)
0.659 0.340 0.000
M79.61 Pain in limb (Shoulder region)
0.659 0.340 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.659 0.341 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.658 0.342 0.000
C67.9 Bladder, unspecified
0.658 0.342 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.658 0.342 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.657 0.343 0.000
M47.2 Other spondylosis with radiculopathy
0.657 0.343 0.000
C92 Myeloid leukaemia
0.657 0.343 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.656 0.343 0.000
K40-K46 Hernia
0.656 0.344 0.000
M86-M90 Other osteopathies
0.656 0.344 0.000
M54.1 Radiculopathy
0.656 0.344 0.000
F38 Other mood [affective] disorders
0.656 0.344 0.000
F34 Persistent mood [affective] disorders
0.656 0.344 0.000
F30 Manic episode
0.656 0.344 0.000
F39 Unspecified mood [affective] disorder
0.656 0.344 0.000
Z81.8 Family history of other mental and behavioural disorders
0.655 0.345 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.655 0.345 0.000
M46 Other inflammatory spondylopathies
0.655 0.345 0.000
K05 Gingivitis and periodontal diseases
0.655 0.345 0.000
M50.9 Cervical disk disorder, unspecified
0.654 0.345 0.000
M50.8 Other cervical disk disorders
0.654 0.345 0.000
M79.7 Fibromyalgia
0.654 0.345 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.654 0.346 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.654 0.346 0.000
T51 Toxic effect of alcohol
0.654 0.346 0.000
H73 Other disorders of tympanic membrane
0.654 0.346 0.000
M54.37 Sciatica (Lumbosacral region)
0.654 0.346 0.000
K61.4 Intrasphincteric abscess
0.654 0.346 0.000
K61.2 Anorectal abscess
0.654 0.346 0.000
K61.1 Rectal abscess
0.654 0.346 0.000
H35 Other retinal disorders
0.654 0.346 0.000
Z93.5 Cystostomy status
0.654 0.346 0.000
Z96.0 Presence of urogenital implants
0.653 0.347 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.653 0.347 0.000
K63.4 Enteroptosis
0.653 0.347 0.000
K63.0 Abscess of intestine
0.653 0.347 0.000
Z10 Routine general health check-up of defined subpopulation
0.653 0.347 0.000
Z99.2 Dependence on renal dialysis
0.653 0.347 0.000
M85 Other disorders of bone density and structure
0.653 0.347 0.000
Q60-Q64 Congenital malformations of the urinary system
0.652 0.348 0.000
H43-H45 Disorders of vitreous body and globe
0.652 0.348 0.000
M79.63 Pain in limb (Forearm)
0.652 0.348 0.000
J17 Pneumonia in diseases classified elsewhere
0.652 0.348 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.652 0.348 0.000
J12 Viral pneumonia, not elsewhere classified
0.652 0.348 0.000
J10 Influenza due to identified influenza virus
0.652 0.348 0.000
J09 Influenza due to certain identified influenza virus
0.652 0.348 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.651 0.349 0.000
M75 Shoulder lesions
0.650 0.350 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.650 0.350 0.000
H25 Senile cataract
0.650 0.350 0.000
K03 Other diseases of hard tissues of teeth
0.649 0.351 0.000
Z93.6 Other artificial openings of urinary tract status
0.649 0.351 0.000
M49 Spondylopathies in diseases classified elsewhere
0.649 0.351 0.000
J18.1 Lobar pneumonia, unspecified
0.649 0.351 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.648 0.352 0.000
H61.1 Non-infective disorders of pinna
0.646 0.354 0.000
Z94.0 Kidney transplant status
0.646 0.354 0.000
J98.1 Pulmonary collapse
0.645 0.355 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.645 0.355 0.000
G50 Disorders of trigeminal nerve
0.644 0.356 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.644 0.356 0.000
Z54 Convalescence
0.643 0.357 0.000
H65.3 Chronic mucoid otitis media
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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