TreeWAS – Variant ID: rs9268577

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000
E10.9 Without complications	1.000	0.000
K90.0 Coeliac disease	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000
K90 Intestinal malabsorption	1.000	0.000
K90-K93 Other diseases of the digestive system	1.000	0.000
E03 Other hypothyroidism	1.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000
Chapter VII Diseases of the eye and adnexa	0.999	0.001
Chapter VI Diseases of the nervous system	0.998	0.002
E10.3 With ophthalmic complications	0.997	0.003
H30-H36 Disorders of choroid and retina	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.995	0.005
G35-G37 Demyelinating diseases of the central nervous system	0.994	0.006
H36 Retinal disorders in diseases classified elsewhere	0.993	0.007
G35 Multiple sclerosis	0.992	0.008
H36.0 Diabetic retinopathy	0.991	0.009
S50-S59 Injuries to the elbow and forearm	0.982	0.018
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.982	0.018
E16 Other disorders of pancreatic internal secretion	0.969	0.031
Chapter IX Diseases of the circulatory system	0.965	0.035
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.964	0.036
S52 Fracture of forearm	0.964	0.036
E10.1 With ketoacidosis	0.963	0.037
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.961	0.039
E16.2 Hypoglycaemia, unspecified	0.960	0.040
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.959	0.041
D50-D53 Nutritional anaemias	0.955	0.045
E14 Unspecified diabetes mellitus	0.951	0.049
Chapter V Mental and behavioural disorders	0.947	0.053
E10.4 With neurological complications	0.946	0.054
I30-I52 Other forms of heart disease	0.941	0.059
S20-S29 Injuries to the thorax	0.939	0.061
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.927	0.073
T66-T78 Other and unspecified effects of external causes	0.922	0.078
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.921	0.079
G50-G59 Nerve, nerve root and plexus disorders	0.917	0.083
R30-R39 Symptoms and signs involving the urinary system	0.911	0.089
R39 Other symptoms and signs involving the urinary system	0.909	0.091
S40-S49 Injuries to the shoulder and upper arm	0.909	0.091
S52.5 Fracture of lower end of radius	0.908	0.092
K55-K64 Other diseases of intestines	0.908	0.092
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.908	0.092
D60-D64 Aplastic and other anaemias	0.907	0.093
Chapter XX External causes of morbidity and mortality	0.903	0.097
T36-T50 Poisoning by drugs, medicaments and biological substances	0.903	0.097
I49 Other cardiac arrhythmias	0.897	0.103
D69 Purpura and other haemorrhagic conditions	0.897	0.103
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.896	0.104
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.895	0.105
D51 Vitamin B12 deficiency anaemia	0.883	0.117
I51 Complications and ill-defined descriptions of heart disease	0.879	0.121
H46-H48 Disorders of optic nerve and visual pathways	0.878	0.122
H40-H42 Glaucoma	0.876	0.124
K63 Other diseases of intestine	0.876	0.124
I31 Other diseases of pericardium	0.875	0.125
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.868	0.132
S52.50 Fracture of lower end of radius (closed)	0.868	0.132
F17 Mental and behavioural disorders due to use of tobacco	0.868	0.132
T78 Adverse effects, not elsewhere classified	0.867	0.133
K63.5 Polyp of colon	0.863	0.137
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.863	0.137
E14.3 With ophthalmic complications	0.860	0.140
K83 Other diseases of biliary tract	0.859	0.141
D68 Other coagulation defects	0.857	0.143
F17.1 Harmful use	0.856	0.144
D64 Other anaemias	0.855	0.145
G56 Mononeuropathies of upper limb	0.854	0.146
K81 Cholecystitis	0.854	0.146
R91 Abnormal findings on diagnostic imaging of lung	0.851	0.149
S42 Fracture of shoulder and upper arm	0.851	0.149
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.850	0.150
E14.9 Without complications	0.849	0.151
H34 Retinal vascular occlusions	0.847	0.153
I49.9 Cardiac arrhythmia, unspecified	0.847	0.153
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.845	0.155
I51.7 Cardiomegaly	0.844	0.156
S52.6 Fracture of lower end of both ulna and radius	0.843	0.157
K70-K77 Diseases of liver	0.842	0.158
I31.3 Pericardial effusion (noninflammatory)	0.840	0.160
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.832	0.168
D50 Iron deficiency anaemia	0.831	0.169
K35-K38 Diseases of appendix	0.829	0.171
T83.1 Mechanical complication of other urinary devices and implants	0.827	0.173
E10.5 With peripheral circulatory complications	0.824	0.176
I49.8 Other specified cardiac arrhythmias	0.823	0.177
K62.1 Rectal polyp	0.823	0.177
K62 Other diseases of anus and rectum	0.821	0.179
K55 Vascular disorders of intestine	0.821	0.179
K40-K46 Hernia	0.820	0.180
S20 Superficial injury of thorax	0.820	0.180
D64.9 Anaemia, unspecified	0.818	0.182
T78.4 Allergy, unspecified	0.817	0.183
T83.0 Mechanical complication of urinary (indwelling) catheter	0.817	0.183
E05 Thyrotoxicosis [hyperthyroidism]	0.814	0.186
E11 Non-insulin-dependent diabetes mellitus	0.813	0.187
S52.1 Fracture of upper end of radius	0.811	0.189
D69.6 Thrombocytopenia, unspecified	0.810	0.190
F30-F39 Mood [affective] disorders	0.808	0.192
R21 Rash and other nonspecific skin eruption	0.806	0.194
S60-S69 Injuries to the wrist and hand	0.802	0.198
G56.2 Lesion of ulnar nerve	0.802	0.198
I70-I79 Diseases of arteries, arterioles and capillaries	0.800	0.200
G90-G99 Other disorders of the nervous system	0.799	0.201
K81.1 Chronic cholecystitis	0.798	0.202
T88 Other complications of surgical and medical care, not elsewhere classified	0.797	0.203
K90.9 Intestinal malabsorption, unspecified	0.796	0.204
E07 Other disorders of thyroid	0.794	0.206
S80-S89 Injuries to the knee and lower leg	0.790	0.210
H40 Glaucoma	0.789	0.211
S90-S99 Injuries to the ankle and foot	0.788	0.212
I60-I69 Cerebrovascular diseases	0.786	0.214
Chapter XXII Codes for special purposes	0.783	0.217
H55-H59 Other disorders of eye and adnexa	0.782	0.218
S00-S09 Injuries to the head	0.782	0.218
S50 Superficial injury of forearm	0.781	0.219
K55.2 Angiodysplasia of colon	0.777	0.223
K83.1 Obstruction of bile duct	0.777	0.223
H33 Retinal detachments and breaks	0.777	0.223
I45 Other conduction disorders	0.774	0.226
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.772	0.228
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.770	0.230
R34 Anuria and oliguria	0.766	0.234
W00-W19 Falls	0.765	0.235
D69.3 Idiopathic thrombocytopenic purpura	0.765	0.235
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.764	0.236
E20-E35 Disorders of other endocrine glands	0.763	0.237
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.762	0.238
H25-H28 Disorders of lens	0.760	0.240
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.760	0.240
E11.3 With ophthalmic complications	0.757	0.243
S27 Injury of other and unspecified intrathoracic organs	0.757	0.243
S52.60 Fracture of lower end of both ulna and radius (closed)	0.756	0.244
G59 Mononeuropathy in diseases classified elsewhere	0.755	0.245
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.752	0.248
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.752	0.248
Chapter I Certain infectious and parasitic diseases	0.751	0.249
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.750	0.250
S22 Fracture of rib(s), sternum and thoracic spine	0.750	0.250
K91.4 Colostomy and enterostomy malfunction	0.749	0.251
H46 Optic neuritis	0.747	0.252
H43-H45 Disorders of vitreous body and globe	0.747	0.253
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.746	0.254
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.744	0.256
T81 Complications of procedures, not elsewhere classified	0.742	0.258
H34.8 Other retinal vascular occlusions	0.741	0.259
K41 Femoral hernia	0.740	0.260
T85 Complications of other internal prosthetic devices, implants and grafts	0.740	0.260
S29 Other and unspecified injuries of thorax	0.740	0.260
D68.2 Hereditary deficiency of other clotting factors	0.736	0.264
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.735	0.265
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.733	0.267
K70 Alcoholic liver disease	0.732	0.268
I10-I15 Hypertensive diseases	0.732	0.268
S42.0 Fracture of clavicle	0.731	0.268
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.731	0.269
K42 Umbilical hernia	0.730	0.270
S32 Fracture of lumbar spine and pelvis	0.729	0.271
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.725	0.274
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.725	0.275
G37 Other demyelinating diseases of central nervous system	0.724	0.276
R39.1 Other difficulties with micturition	0.723	0.276
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.722	0.277
D52 Folate deficiency anaemia	0.722	0.278
E13 Other specified diabetes mellitus	0.719	0.281
G30-G32 Other degenerative diseases of the nervous system	0.718	0.282
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E10.2 With renal complications	0.717	0.283
E10.0 With coma	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
K90.8 Other intestinal malabsorption	0.717	0.283
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.717	0.283
K90.3 Pancreatic steatorrhoea	0.717	0.283
K90.2 Blind loop syndrome, not elsewhere classified	0.717	0.283
K90.1 Tropical sprue	0.717	0.283
K93 Disorders of other digestive organs in diseases classified elsewhere	0.717	0.283
E03.8 Other specified hypothyroidism	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283
E00 Congenital iodine-deficiency syndrome	0.717	0.283
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283
S51 Open wound of forearm	0.716	0.284
G70-G73 Diseases of myoneural junction and muscle	0.715	0.284
G00-G09 Inflammatory diseases of the central nervous system	0.715	0.284
R93 Abnormal findings on diagnostic imaging of other body structures	0.715	0.285
T93 Sequelae of injuries of lower limb	0.714	0.286
H32 Chorioretinal disorders in diseases classified elsewhere	0.714	0.286
H31 Other disorders of choroid	0.714	0.286
H30 Chorioretinal inflammation	0.714	0.286
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.713	0.287
D55-D59 Haemolytic anaemias	0.713	0.287
G36 Other acute disseminated demyelination	0.713	0.287
H47 Other disorders of optic [2nd] nerve and visual pathways	0.713	0.287
K82 Other diseases of gallbladder	0.713	0.287
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.712	0.288
K83.0 Cholangitis	0.712	0.288
H36.8 Other retinal disorders in diseases classified elsewhere	0.712	0.288
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.711	0.289
D50.8 Other iron deficiency anaemias	0.710	0.290
R26 Abnormalities of gait and mobility	0.709	0.291
R23 Other skin changes	0.709	0.291
V40-V49 Car occupant injured in transport accident	0.708	0.292
I46 Cardiac arrest	0.706	0.294
K75 Other inflammatory liver diseases	0.705	0.295
S52.0 Fracture of upper end of ulna	0.705	0.295
S59 Other and unspecified injuries of forearm	0.704	0.296
S58 Traumatic amputation of forearm	0.704	0.296
S57 Crushing injury of forearm	0.704	0.296
S56 Injury of muscle and tendon at forearm level	0.704	0.296
S55 Injury of blood vessels at forearm level	0.704	0.296
S54 Injury of nerves at forearm level	0.704	0.296
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.704	0.296
E15 Nondiabetic hypoglycaemic coma	0.704	0.296
S70-S79 Injuries to the hip and thigh	0.703	0.297
S52.10 Fracture of upper end of radius (closed)	0.701	0.299
H40.0 Glaucoma suspect	0.700	0.300
T88.7 Unspecified adverse effect of drug or medicament	0.700	0.300
X20-X29 Contact with venomous animals and plants	0.698	0.302
I42 Cardiomyopathy	0.698	0.302
T79-T79 Certain early complications of trauma	0.697	0.303
G54 Nerve root and plexus disorders	0.696	0.304
E16.9 Disorder of pancreatic internal secretion, unspecified	0.695	0.305
E16.8 Other specified disorders of pancreatic internal secretion	0.695	0.305
E16.4 Abnormal secretion of gastrin	0.695	0.305
E16.3 Increased secretion of glucagon	0.695	0.305
E16.1 Other hypoglycaemia	0.695	0.305
E16.0 Drug-induced hypoglycaemia without coma	0.695	0.305
G51 Facial nerve disorders	0.695	0.305
I30 Acute pericarditis	0.695	0.305
F60-F69 Disorders of adult personality and behaviour	0.694	0.306
E06 Thyroiditis	0.694	0.306
I95-I99 Other and unspecified disorders of the circulatory system	0.694	0.306
H40.1 Primary open-angle glaucoma	0.694	0.306
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.693	0.307
I00-I02 Acute rheumatic fever	0.692	0.308
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.692	0.308
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.692	0.308
T87 Complications peculiar to reattachment and amputation	0.691	0.309
T86 Failure and rejection of transplanted organs and tissues	0.691	0.309
T80 Complications following infusion, transfusion and therapeutic injection	0.691	0.309
T83.3 Mechanical complication of intra-uterine contraceptive device	0.691	0.309
S52.9 Fracture of forearm, part unspecified	0.691	0.309
S52.8 Fracture of other parts of forearm	0.691	0.309
S52.7 Multiple fractures of forearm	0.691	0.309
S52.4 Fracture of shafts of both ulna and radius	0.691	0.309
S52.3 Fracture of shaft of radius	0.691	0.309
S52.2 Fracture of shaft of ulna	0.691	0.309
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.691	0.309
G80-G83 Cerebral palsy and other paralytic syndromes	0.690	0.310
K36 Other appendicitis	0.690	0.310
D67 Hereditary factor IX deficiency	0.689	0.311
D66 Hereditary factor VIII deficiency	0.689	0.311
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.689	0.311
H26 Other cataract	0.688	0.312
K62.3 Rectal prolapse	0.687	0.313
R95-R99 Ill-defined and unknown causes of mortality	0.687	0.313
S42.2 Fracture of upper end of humerus	0.687	0.313
I77 Other disorders of arteries and arterioles	0.687	0.313
G40-G47 Episodic and paroxysmal disorders	0.685	0.315
D53 Other nutritional anaemias	0.685	0.315
D62 Acute posthaemorrhagic anaemia	0.684	0.316
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.683	0.317
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.683	0.317
K81.9 Cholecystitis, unspecified	0.682	0.317
E14.8 With unspecified complications	0.682	0.318
E14.7 With multiple complications	0.682	0.318
E14.6 With other specified complications	0.682	0.318
E14.5 With peripheral circulatory complications	0.682	0.318
E14.4 With neurological complications	0.682	0.318
E14.2 Withrenal complications	0.682	0.318
E14.1 With ketoacidosis	0.682	0.318
E14.0 With coma	0.682	0.318
S20.3 Other superficial injuries of front wall of thorax	0.682	0.318
Y86 Sequelae of other accidents	0.681	0.319
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.681	0.319
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.680	0.320
D61 Other aplastic anaemias	0.680	0.320
S42.1 Fracture of scapula	0.680	0.320
I12 Hypertensive renal disease	0.680	0.320
I44 Atrioventricular and left bundle-branch block	0.679	0.321
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.679	0.321
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.679	0.321
F80-F89 Disorders of psychological development	0.679	0.321
F70-F79 Mental retardation	0.679	0.321
I05-I09 Chronic rheumatic heart diseases	0.675	0.325
I52 Other heart disorders in diseases classified elsewhere	0.675	0.325
I48 Atrial fibrillation and flutter	0.675	0.325
I43 Cardiomyopathy in diseases classified elsewhere	0.675	0.325
I41 Myocarditis in diseases classified elsewhere	0.675	0.325
I40 Acute myocarditis	0.675	0.325
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.675	0.325
I37 Pulmonary valve disorders	0.675	0.325
I36 Nonrheumatic tricuspid valve disorders	0.675	0.325
I33 Acute and subacute endocarditis	0.675	0.325
I32 Pericarditis in diseases classified elsewhere	0.675	0.325
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.673	0.327
S26 Injury of heart	0.673	0.327
S25 Injury of blood vessels of thorax	0.673	0.327
S24 Injury of nerves and spinal cord at thorax level	0.673	0.327
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.673	0.327
S21 Open wound of thorax	0.673	0.327
R90 Abnormal findings on diagnostic imaging of central nervous system	0.673	0.327
D68.9 Coagulation defect, unspecified	0.672	0.328
I60 Subarachnoid haemorrhage	0.671	0.328
T78.2 Anaphylactic shock, unspecified	0.671	0.329
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.670	0.330
I49.5 Sick sinus syndrome	0.670	0.330
H10-H13 Disorders of conjunctiva	0.670	0.330
I45.1 Other and unspecified right bundle-branch block	0.669	0.331
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.668	0.332
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.667	0.333
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.665	0.335
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.665	0.335
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.665	0.335
T83.2 Mechanical complication of graft of urinary organ	0.665	0.335
S40 Superficial injury of shoulder and upper arm	0.665	0.335
S20.8 Superficial injuries of other and unspecified parts of thorax	0.664	0.336
S60 Superficial injury of wrist and hand	0.662	0.338
S42.3 Fracture of shaft of humerus	0.662	0.338
T75 Effects of other external causes	0.661	0.339
T74 Maltreatment syndromes	0.661	0.339
T73 Effects of other deprivation	0.661	0.339
T70 Effects of air pressure and water pressure	0.661	0.339
T69 Other effects of reduced temperature	0.661	0.339
T67 Effects of heat and light	0.661	0.339
T71 Asphyxiation	0.661	0.339
T68 Hypothermia	0.661	0.339
T66 Unspecified effects of radiation	0.661	0.339
E50-E64 Other nutritional deficiencies	0.661	0.339
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.660	0.340
D68.8 Other specified coagulation defects	0.660	0.340
G91 Hydrocephalus	0.660	0.340
G58 Other mononeuropathies	0.659	0.341
Y60-Y69 Misadventures to patients during surgical and medical care	0.659	0.341
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.659	0.341
G53 Cranial nerve disorders in diseases classified elsewhere	0.658	0.342
G52 Disorders of other cranial nerves	0.658	0.342
X60-X84 Intentional self-harm	0.657	0.342
E05.9 Thyrotoxicosis, unspecified	0.657	0.343
T15-T19 Effects of foreign body entering through natural orifice	0.657	0.343
T90 Sequelae of injuries of head	0.655	0.345
V20-V29 Motorcycle rider injured in transport accident	0.654	0.345
F30 Manic episode	0.654	0.346
R36 Urethral discharge	0.653	0.347
I49.4 Other and unspecified premature depolarisation	0.653	0.347
E65-E68 Obesity and other hyperalimentation	0.653	0.347
I63 Cerebral infarction	0.652	0.347
R39.2 Extrarenal uraemia	0.652	0.348
R39.0 Extravasation of urine	0.652	0.348
S49 Other and unspecified injuries of shoulder and upper arm	0.652	0.348
S48 Traumatic amputation of shoulder and upper arm	0.652	0.348
S46 Injury of muscle and tendon at shoulder and upper arm level	0.652	0.348
S45 Injury of blood vessels at shoulder and upper arm level	0.652	0.348
S44 Injury of nerves at shoulder and upper arm level	0.652	0.348
S41 Open wound of shoulder and upper arm	0.652	0.348
S47 Crushing injury of shoulder and upper arm	0.652	0.348
S01 Open wound of head	0.651	0.349
S52.51 Fracture of lower end of radius (open)	0.651	0.349
K64 Haemorrhoids and perianal venous thrombosis	0.651	0.349
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.650	0.350
F99-F99 Unspecified mental disorder	0.648	0.352
Y35-Y36 Legal intervention and operations of war	0.647	0.352
Y10-Y34 Event of undetermined intent	0.647	0.352
Y00-Y09 Assault	0.647	0.352
X85-X99 Assault	0.647	0.352
X58-X59 Accidental exposure to other and unspecified factors	0.647	0.352
X50-X57 Overexertion, travel and privation	0.647	0.352
X40-X49 Accidental poisoning by and exposure to noxious substances	0.647	0.352
X30-X39 Exposure to forces of nature	0.647	0.352
X10-X19 Contact with heat and hot substances	0.647	0.352
X00-X09 Exposure to smoke, fire and flames	0.647	0.352
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.647	0.352
W75-W84 Other accidental threats to breathing	0.647	0.352
W65-W74 Accidental drowning and submersion	0.647	0.352
W50-W64 Exposure to animate mechanical forces	0.647	0.352
V98-V99 Other and unspecified transport accidents	0.647	0.352
V95-V97 Air and space transport accidents	0.647	0.352
V90-V94 Water transport accidents	0.647	0.352
V80-V89 Other land transport accidents	0.647	0.352
V70-V79 Bus occupant injured in transport accident	0.647	0.352
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.647	0.352
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.647	0.352
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.647	0.352
V01-V09 Pedestrian injured in transport accident	0.647	0.352
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.647	0.353
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.647	0.353
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.647	0.353
T46 Poisoning by agents primarily affecting the cardiovascular system	0.647	0.353
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.647	0.353
T41 Poisoning by anaesthetics and therapeutic gases	0.647	0.353
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.647	0.353
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.647	0.353
T36 Poisoning by systemic antibiotics	0.647	0.353
S42.00 Fracture of clavicle (closed)	0.646	0.354
E07.9 Disorder of thyroid, unspecified	0.646	0.354
G56.0 Carpal tunnel syndrome	0.645	0.355
I49.2 Junctional premature depolarisation	0.643	0.357
I49.1 Atrial premature depolarisation	0.643	0.357
D69.9 Haemorrhagic condition, unspecified	0.643	0.357
D69.8 Other specified haemorrhagic conditions	0.643	0.357
D69.5 Secondary thrombocytopenia	0.643	0.357
D69.4 Other primary thrombocytopenia	0.643	0.357
D69.2 Other nonthrombocytopenic purpura	0.643	0.357
D69.1 Qualitative platelet defects	0.643	0.357
D69.0 Allergic purpura	0.643	0.357
I12.0 Hypertensive renal disease with renal failure	0.643	0.357
K63.2 Fistula of intestine	0.643	0.357
R92 Abnormal findings on diagnostic imaging of breast	0.642	0.358
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.642	0.358
F18 Mental and behavioural disorders due to use of volatile solvents	0.642	0.358
F16 Mental and behavioural disorders due to use of hallucinogens	0.642	0.358
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.642	0.358
F14 Mental and behavioural disorders due to use of cocaine	0.642	0.358
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.642	0.358
F12 Mental and behavioural disorders due to use of cannabinoids	0.642	0.358
F11 Mental and behavioural disorders due to use of opioids	0.642	0.358
I51.9 Heart disease, unspecified	0.641	0.359
K83.8 Other specified diseases of biliary tract	0.641	0.359
M86-M90 Other osteopathies	0.640	0.360
R30 Pain associated with micturition	0.639	0.361
G59.0 Diabetic mononeuropathy	0.639	0.361
S30 Superficial injury of abdomen, lower back and pelvis	0.639	0.361
E11.6 With other specified complications	0.638	0.362
I26 Pulmonary embolism	0.638	0.362
K72 Hepatic failure, not elsewhere classified	0.637	0.362
S50.9 Superficial injury of forearm, unspecified	0.637	0.363
D50.9 Iron deficiency anaemia, unspecified	0.637	0.363
E11.5 With peripheral circulatory complications	0.637	0.363
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.637	0.363
K38 Other diseases of appendix	0.636	0.364
G90 Disorders of autonomic nervous system	0.635	0.365
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.633	0.367
D51.8 Other vitamin B12 deficiency anaemias	0.633	0.367
D51.3 Other dietary vitamin B12 deficiency anaemia	0.633	0.367
D51.2 Transcobalamin II deficiency	0.633	0.367
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.633	0.367
I74 Arterial embolism and thrombosis	0.631	0.369
K70.4 Alcoholic hepatic failure	0.630	0.370
S42.4 Fracture of lower end of humerus	0.630	0.370
I51.6 Cardiovascular disease, unspecified	0.630	0.370
I51.5 Myocardial degeneration	0.630	0.370
I51.4 Myocarditis, unspecified	0.630	0.370
I51.3 Intracardiac thrombosis, not elsewhere classified	0.630	0.370
I51.2 Rupture of papillary muscle, not elsewhere classified	0.630	0.370
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.630	0.370
I51.0 Cardiac septal defect, acquired	0.630	0.370
T43.2 Other and unspecified antidepressants	0.630	0.370
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.629	0.371
S82 Fracture of lower leg, including ankle	0.629	0.371
H42 Glaucoma in diseases classified elsewhere	0.628	0.372
K63.9 Disease of intestine, unspecified	0.628	0.372
K63.4 Enteroptosis	0.628	0.372
K63.0 Abscess of intestine	0.628	0.372
K37 Unspecified appendicitis	0.628	0.372
I31.8 Other specified diseases of pericardium	0.628	0.372
I31.2 Haemopericardium, not elsewhere classified	0.628	0.372
I31.1 Chronic constrictive pericarditis	0.628	0.372
I31.0 Chronic adhesive pericarditis	0.628	0.372
R76 Other abnormal immunological findings in serum	0.628	0.372
E11.1 With ketoacidosis	0.627	0.373
S27.0 Traumatic pneumothorax	0.626	0.374
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.625	0.375
T85.2 Mechanical complication of intraocular lens	0.624	0.376
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.623	0.377
S37 Injury of urinary and pelvic organs	0.623	0.377
S36 Injury of intra-abdominal organs	0.623	0.377
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.623	0.377
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.623	0.377
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.623	0.377
S31 Open wound of abdomen, lower back and pelvis	0.623	0.377
F17.9 Unspecified mental and behavioural disorder	0.622	0.378
F17.8 Other mental and behavioural disorders	0.622	0.378
F17.7 Residual and late-onset psychotic disorder	0.622	0.378
F17.6 Amnesic syndrome	0.622	0.378
F17.5 Psychotic disorder	0.622	0.378
F17.4 Withdrawal state with delirium	0.622	0.378
F17.3 Withdrawal state	0.622	0.378
F17.0 Acute intoxication	0.622	0.378
H33.0 Retinal detachment with retinal break	0.622	0.378
T78.9 Adverse effect, unspecified	0.621	0.378
T78.8 Other adverse effects, not elsewhere classified	0.621	0.378

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations