TreeWAS – Variant ID: rs9445732

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.281	0.719
Chapter XXI Factors influencing health status and contact with health services	0.274	0.726
Chapter X Diseases of the respiratory system	0.267	0.733
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.260	0.740
J40-J47 Chronic lower respiratory diseases	0.254	0.746
Chapter XI Diseases of the digestive system	0.250	0.750
J45 Asthma	0.246	0.754
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.244	0.756
J45.9 Asthma, unspecified	0.240	0.760
Z00-Z13 Persons encountering health services for examination and investigation	0.231	0.769
Chapter VII Diseases of the eye and adnexa	0.229	0.771
Z40-Z54 Persons encountering health services for specific procedures and health care	0.227	0.773
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.225	0.775
Z87 Personal history of other diseases and conditions	0.220	0.780
K20-K31 Diseases of oesophagus, stomach and duodenum	0.220	0.780
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.220	0.780
Chapter VI Diseases of the nervous system	0.219	0.781
Chapter II Neoplasms	0.216	0.784
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.211	0.789
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.206	0.794
Z90 Acquired absence of organs, not elsewhere classified	0.206	0.794
Chapter I Certain infectious and parasitic diseases	0.205	0.795
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.205	0.795
J90-J94 Other diseases of pleura	0.202	0.798
Z86 Personal history of certain other diseases	0.202	0.798
Chapter XXII Codes for special purposes	0.201	0.798
Chapter XX External causes of morbidity and mortality	0.201	0.798
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.201	0.798
Chapter XVI Certain conditions originating in the perinatal period	0.201	0.798
Chapter XV Pregnancy, childbirth and the puerperium	0.201	0.798
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.201	0.798
Chapter XII Diseases of the skin and subcutaneous tissue	0.201	0.798
Chapter VIII Diseases of the ear and mastoid process	0.201	0.798
Z85 Personal history of malignant neoplasm	0.201	0.799
Chapter IX Diseases of the circulatory system	0.200	0.800
K30 Dyspepsia	0.197	0.803
J09-J18 Influenza and pneumonia	0.197	0.803
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.197	0.803
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.197	0.803
Z96 Presence of other functional implants	0.195	0.805
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.194	0.806
K55-K64 Other diseases of intestines	0.193	0.807
Chapter IV Endocrine, nutritional and metabolic diseases	0.193	0.807
J95-J99 Other diseases of the respiratory system	0.191	0.809
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.191	0.809
J80-J84 Other respiratory diseases principally affecting the interstitium	0.191	0.809
J60-J70 Lung diseases due to external agents	0.191	0.809
J30-J39 Other diseases of upper respiratory tract	0.191	0.809
J00-J06 Acute upper respiratory infections	0.191	0.809
Z92 Personal history of medical treatment	0.191	0.809
J20-J22 Other acute lower respiratory infections	0.191	0.809
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.189	0.810
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.189	0.810
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.188	0.811
Z51 Other medical care	0.188	0.812
Z87.1 Personal history of diseases of the digestive system	0.187	0.813
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.187	0.813
Z98 Other postsurgical states	0.187	0.813
Z97 Presence of other devices	0.187	0.813
Z95 Presence of cardiac and vascular implants and grafts	0.187	0.813
Z94 Transplanted organ and tissue status	0.187	0.813
Z93 Artificial opening status	0.187	0.813
Z91 Personal history of risk-factors, not elsewhere classified	0.187	0.813
Z89 Acquired absence of limb	0.187	0.813
Z84 Family history of other conditions	0.187	0.813
Z83 Family history of other specific disorders	0.187	0.813
Z81 Family history of mental and behavioural disorders	0.187	0.813
Z80 Family history of malignant neoplasm	0.187	0.813
K40-K46 Hernia	0.186	0.814
Chapter V Mental and behavioural disorders	0.186	0.814
H40-H42 Glaucoma	0.185	0.815
J44 Other chronic obstructive pulmonary disease	0.182	0.817
J43 Emphysema	0.182	0.817
J41 Simple and mucopurulent chronic bronchitis	0.182	0.817
J47 Bronchiectasis	0.182	0.817
J46 Status asthmaticus	0.182	0.817
J42 Unspecified chronic bronchitis	0.182	0.817
J40 Bronchitis, not specified as acute or chronic	0.182	0.817
Z03 Medical observation and evaluation for suspected diseases and conditions	0.182	0.818
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.182	0.818
Chapter XIV Diseases of the genitourinary system	0.180	0.820
K90-K93 Other diseases of the digestive system	0.179	0.820
K70-K77 Diseases of liver	0.179	0.820
K65-K67 Diseases of peritoneum	0.179	0.820
K35-K38 Diseases of appendix	0.179	0.820
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.179	0.820
Z47 Other orthopaedic follow-up care	0.177	0.822
Z70-Z76 Persons encountering health services in other circumstances	0.177	0.823
J45.8 Mixed asthma	0.176	0.824
J45.1 Nonallergic asthma	0.176	0.824
J45.0 Predominantly allergic asthma	0.176	0.824
D60-D64 Aplastic and other anaemias	0.176	0.824
G40-G47 Episodic and paroxysmal disorders	0.175	0.825
R95-R99 Ill-defined and unknown causes of mortality	0.175	0.825
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.175	0.825
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.175	0.825
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.175	0.825
R47-R49 Symptoms and signs involving speech and voice	0.175	0.825
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.175	0.825
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.175	0.825
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.175	0.825
Z08 Follow-up examination after treatment for malignant neoplasm	0.175	0.825
R11 Nausea and vomiting	0.175	0.825
M70-M79 Other soft tissue disorders	0.174	0.826
H25-H28 Disorders of lens	0.173	0.827
M20-M25 Other joint disorders	0.172	0.827
C43-C44 Melanoma and other malignant neoplasms of skin	0.170	0.830
K50-K52 Noninfective enteritis and colitis	0.168	0.832
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.168	0.832
R50-R69 General symptoms and signs	0.167	0.832
Z87.4 Personal history of diseases of the genito-urinary system	0.167	0.833
R10 Abdominal and pelvic pain	0.167	0.833
Z90.4 Acquired absence of other parts of digestive tract	0.166	0.833
M15-M19 Arthrosis	0.166	0.834
Z13 Special screening examination for other diseases and disorders	0.165	0.834
Z12 Special screening examination for neoplasms	0.165	0.834
Z11 Special screening examination for infectious and parasitic diseases	0.165	0.834
Z10 Routine general health check-up of defined subpopulation	0.165	0.834
Z04 Examination and observation for other reasons	0.165	0.834
Z02 Examination and encounter for administrative purposes	0.165	0.834
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.165	0.834
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.165	0.834
H55-H59 Other disorders of eye and adnexa	0.164	0.836
H53-H54 Visual disturbances and blindness	0.164	0.836
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.164	0.836
H46-H48 Disorders of optic nerve and visual pathways	0.164	0.836
H43-H45 Disorders of vitreous body and globe	0.164	0.836
H30-H36 Disorders of choroid and retina	0.164	0.836
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.164	0.836
H10-H13 Disorders of conjunctiva	0.164	0.836
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.164	0.836
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.164	0.836
R30-R39 Symptoms and signs involving the urinary system	0.163	0.836
Z54 Convalescence	0.163	0.837
Z52 Donors of organs and tissues	0.163	0.837
Z50 Care involving use of rehabilitation procedures	0.163	0.837
Z49 Care involving dialysis	0.163	0.837
Z48 Other surgical follow-up care	0.163	0.837
Z46 Fitting and adjustment of other devices	0.163	0.837
Z45 Adjustment and management of implanted device	0.163	0.837
Z44 Fitting and adjustment of external prosthetic device	0.163	0.837
Z43 Attention to artificial openings	0.163	0.837
Z42 Follow-up care involving plastic surgery	0.163	0.837
Z41 Procedures for purposes other than remedying health state	0.163	0.837
Z40 Prophylactic surgery	0.163	0.837
R13 Dysphagia	0.162	0.838
Z51.2 Other chemotherapy	0.162	0.838
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.162	0.838
M91-M94 Chondropathies	0.162	0.838
M86-M90 Other osteopathies	0.162	0.838
M80-M85 Disorders of bone density and structure	0.162	0.838
M65-M68 Disorders of synovium and tendon	0.162	0.838
M60-M63 Disorders of muscles	0.162	0.838
M50-M54 Other dorsopathies	0.162	0.838
M45-M49 Spondylopathies	0.162	0.838
M40-M43 Deforming dorsopathies	0.162	0.838
M05-M14 Inflammatory polyarthropathies	0.162	0.838
M00-M03 Infectious arthropathies	0.162	0.838
K29 Gastritis and duodenitis	0.161	0.838
K21 Gastro-oesophageal reflux disease	0.159	0.840
Z86.6 Personal history of diseases of the nervous system and sense organs	0.159	0.840
Z86.4 Personal history of psychoactive substance abuse	0.159	0.841
Z87.8 Personal history of other specified conditions	0.158	0.842
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.158	0.842
Z87.6 Personal history of certain conditions arising in the perinatal period	0.158	0.842
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.158	0.842
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.158	0.842
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.158	0.842
Z87.0 Personal history of diseases of the respiratory system	0.158	0.842
K31 Other diseases of stomach and duodenum	0.158	0.842
K28 Gastrojejunal ulcer	0.158	0.842
K27 Peptic ulcer, site unspecified	0.158	0.842
K26 Duodenal ulcer	0.158	0.842
K25 Gastric ulcer	0.158	0.842
K23 Disorders of oesophagus in diseases classified elsewhere	0.158	0.842
K22 Other diseases of oesophagus	0.158	0.842
K20 Oesophagitis	0.158	0.842
D80-D89 Certain disorders involving the immune mechanism	0.158	0.842
D70-D77 Other diseases of blood and blood-forming organs	0.158	0.842
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.158	0.842
D55-D59 Haemolytic anaemias	0.158	0.842
D50-D53 Nutritional anaemias	0.158	0.842
G90-G99 Other disorders of the nervous system	0.157	0.843
G80-G83 Cerebral palsy and other paralytic syndromes	0.157	0.843
G70-G73 Diseases of myoneural junction and muscle	0.157	0.843
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.157	0.843
G35-G37 Demyelinating diseases of the central nervous system	0.157	0.843
G30-G32 Other degenerative diseases of the nervous system	0.157	0.843
G20-G26 Extrapyramidal and movement disorders	0.157	0.843
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.157	0.843
G00-G09 Inflammatory diseases of the central nervous system	0.157	0.843
G50-G59 Nerve, nerve root and plexus disorders	0.156	0.844
J90 Pleural effusion, not elsewhere classified	0.156	0.844
Z53 Persons encountering health services for specifie procedures, not carried out	0.155	0.844
D37-D48 Neoplasms of uncertain or unknown behaviour	0.155	0.845
D10-D36 Benign neoplasms	0.155	0.845
D00-D09 In situ neoplasms	0.155	0.845
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.155	0.845
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.155	0.845
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.155	0.845
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.155	0.845
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.155	0.845
C64-C68 Malignant neoplasms of urinary tract	0.155	0.845
C60-C63 Malignant neoplasms of male genital organs	0.155	0.845
C51-C58 Malignant neoplasms of female genital organs	0.155	0.845
C50-C50 Malignant neoplasm of breast	0.155	0.845
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.155	0.845
C40-C41 Malignant neoplasms of bone and articular cartilage	0.155	0.845
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.155	0.845
C15-C26 Malignant neoplasms of digestive organs	0.155	0.845
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.155	0.845
Z37 Outcome of delivery	0.155	0.845
H40 Glaucoma	0.154	0.846
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.153	0.847
K62 Other diseases of anus and rectum	0.152	0.848
R04 Haemorrhage from respiratory passages	0.152	0.848
Z85.3 Personal history of malignant neoplasm of breast	0.152	0.848
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.151	0.849
R18 Ascites	0.151	0.849
R17 Unspecified jaundice	0.151	0.849
R15 Faecal incontinence	0.151	0.849
R14 Flatulence and related conditions	0.151	0.849
R12 Heartburn	0.151	0.849
B95-B98 Bacterial, viral and other infectious agents	0.151	0.849
R79 Other abnormal findings of blood chemistry	0.151	0.849
Z92.2 Personal history of long-term (current) use of other medicaments	0.149	0.851
K58 Irritable bowel syndrome	0.148	0.851
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.148	0.852
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.148	0.852
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.148	0.852
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.148	0.852
Z82.3 Family history of stroke	0.148	0.852
Z82.2 Family history of deafness and hearing loss	0.148	0.852
Z82.1 Family history of blindness and visual loss	0.148	0.852
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.148	0.852
Z96.6 Presence of orthopaedic joint implants	0.148	0.852
Z90.8 Acquired absence of other organs	0.147	0.852
Z90.7 Acquired absence of genital organ(s)	0.147	0.852
Z90.6 Acquired absence of other parts of urinary tract	0.147	0.852
Z90.5 Acquired absence of kidney	0.147	0.852
Z90.3 Acquired absence of part of stomach	0.147	0.852
Z90.2 Acquired absence of lung [part of]	0.147	0.852
Z90.1 Acquired absence of breast(s)	0.147	0.852
Z90.0 Acquired absence of part of head and neck	0.147	0.852
K42 Umbilical hernia	0.147	0.853
Z03.8 Observation for other suspected diseases and conditions	0.147	0.853
B99-B99 Other infectious diseases	0.147	0.853
B90-B94 Sequelae of infectious and parasitic diseases	0.147	0.853
B85-B89 Pediculosis, acariasis and other infestations	0.147	0.853
B65-B83 Helminthiases	0.147	0.853
B50-B64 Protozoal diseases	0.147	0.853
B35-B49 Mycoses	0.147	0.853
B25-B34 Other viral diseases	0.147	0.853
B20-B24 Human immunodeficiency virus [HIV] disease	0.147	0.853
B15-B19 Viral hepatitis	0.147	0.853
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.147	0.853
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.147	0.853
A80-A89 Viral infections of the central nervous system	0.147	0.853
A75-A79 Rickettsioses	0.147	0.853
A70-A74 Other diseases caused by chlamydiae	0.147	0.853
A65-A69 Other spirochaetal diseases	0.147	0.853
A50-A64 Infections with a predominantly sexual mode of transmission	0.147	0.853
A30-A49 Other bacterial diseases	0.147	0.853
A20-A28 Certain zoonotic bacterial diseases	0.147	0.853
A15-A19 Tuberculosis	0.147	0.853
A00-A09 Intestinal infectious diseases	0.147	0.853
J18 Pneumonia, organism unspecified	0.147	0.853
Z39 Postpartum care and examination	0.147	0.853
Z38 Liveborn infants according to place of birth	0.147	0.853
Z36 Antenatal screening	0.147	0.853
Z35 Supervision of high-risk pregnancy	0.147	0.853
Z34 Supervision of normal pregnancy	0.147	0.853
Z32 Pregnancy examination and test	0.147	0.853
Z31 Procreative management	0.147	0.853
Z30 Contraceptive management	0.147	0.853
Z33 Pregnant state, incidental	0.147	0.853
Z09.0 Follow-up examination after surgery for other conditions	0.147	0.853
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.146	0.854
E65-E68 Obesity and other hyperalimentation	0.146	0.854
J94 Other pleural conditions	0.145	0.855
J93 Pneumothorax	0.145	0.855
J92 Pleural plaque	0.145	0.855
J91 Pleural effusion in conditions classified elsewhere	0.145	0.855
Z86.5 Personal history of other mental and behavioural disorders	0.145	0.855
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.145	0.855
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.145	0.855
Z86.1 Personal history of infectious and parasitic diseases	0.145	0.855
Z86.0 Personal history of other neoplasms	0.145	0.855
R19 Other symptoms and signs involving the digestive system and abdomen	0.145	0.855
H90-H95 Other disorders of ear	0.145	0.855
H80-H83 Diseases of inner ear	0.145	0.855
H65-H75 Diseases of middle ear and mastoid	0.145	0.855
H60-H62 Diseases of external ear	0.145	0.855
L80-L99 Other disorders of the skin and subcutaneous tissue	0.145	0.855
L60-L75 Disorders of skin appendages	0.145	0.855
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.145	0.855
L50-L54 Urticaria and erythema	0.145	0.855
L40-L45 Papulosquamous disorders	0.145	0.855
L20-L30 Dermatitis and eczema	0.145	0.855
L10-L14 Bullous disorders	0.145	0.855
L00-L08 Infections of the skin and subcutaneous tissue	0.145	0.855
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.145	0.855
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.145	0.855
T79-T79 Certain early complications of trauma	0.145	0.855
T66-T78 Other and unspecified effects of external causes	0.145	0.855
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.145	0.855
T36-T50 Poisoning by drugs, medicaments and biological substances	0.145	0.855
T33-T35 Frostbite	0.145	0.855
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.145	0.855
T26-T28 Burns and corrosions confined to eye and internal organs	0.145	0.855
T20-T25 Burns and corrosions of external body surface, specified by site	0.145	0.855
T15-T19 Effects of foreign body entering through natural orifice	0.145	0.855
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.145	0.855
T00-T07 Injuries involving multiple body regions	0.145	0.855
S90-S99 Injuries to the ankle and foot	0.145	0.855
S80-S89 Injuries to the knee and lower leg	0.145	0.855
S70-S79 Injuries to the hip and thigh	0.145	0.855
S60-S69 Injuries to the wrist and hand	0.145	0.855
S50-S59 Injuries to the elbow and forearm	0.145	0.855
S40-S49 Injuries to the shoulder and upper arm	0.145	0.855
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.145	0.855
S20-S29 Injuries to the thorax	0.145	0.855
S10-S19 Injuries to the neck	0.145	0.855
S00-S09 Injuries to the head	0.145	0.855
O94-O99 Other obstetric conditions, not elsewhere classified	0.145	0.855
O85-O92 Complications predominantly related to the puerperium	0.145	0.855
O80-O84 Delivery	0.145	0.855
O60-O75 Complications of labour and delivery	0.145	0.855
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.145	0.855
O20-O29 Other maternal disorders predominantly related to pregnancy	0.145	0.855
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.145	0.855
O00-O08 Pregnancy with abortive outcome	0.145	0.855
P90-P96 Other disorders originating in the perinatal period	0.145	0.855
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.145	0.855
P75-P78 Digestive system disorders of fetus and newborn	0.145	0.855
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.145	0.855
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.145	0.855
P35-P39 Infections specific to the perinatal period	0.145	0.855
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.145	0.855
P10-P15 Birth trauma	0.145	0.855
P05-P08 Disorders related to length of gestation and fetal growth	0.145	0.855
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.145	0.855
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.145	0.855
Q80-Q89 Other congenital malformations	0.145	0.855
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.145	0.855
Q60-Q64 Congenital malformations of the urinary system	0.145	0.855
Q50-Q56 Congenital malformations of genital organs	0.145	0.855
Q38-Q45 Other congenital malformations of the digestive system	0.145	0.855
Q35-Q37 Cleft lip and cleft palate	0.145	0.855
Q30-Q34 Congenital malformations of the respiratory system	0.145	0.855
Q20-Q28 Congenital malformations of the circulatory system	0.145	0.855
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.145	0.855
Q00-Q07 Congenital malformations of the nervous system	0.145	0.855
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.145	0.855
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.145	0.855
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.145	0.855
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.145	0.855
Y60-Y69 Misadventures to patients during surgical and medical care	0.145	0.855
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.145	0.855
Y35-Y36 Legal intervention and operations of war	0.145	0.855
Y10-Y34 Event of undetermined intent	0.145	0.855
Y00-Y09 Assault	0.145	0.855
X85-X99 Assault	0.145	0.855
X60-X84 Intentional self-harm	0.145	0.855
X58-X59 Accidental exposure to other and unspecified factors	0.145	0.855
X50-X57 Overexertion, travel and privation	0.145	0.855
X40-X49 Accidental poisoning by and exposure to noxious substances	0.145	0.855
X30-X39 Exposure to forces of nature	0.145	0.855
X20-X29 Contact with venomous animals and plants	0.145	0.855
X10-X19 Contact with heat and hot substances	0.145	0.855
X00-X09 Exposure to smoke, fire and flames	0.145	0.855
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.145	0.855
W75-W84 Other accidental threats to breathing	0.145	0.855
W65-W74 Accidental drowning and submersion	0.145	0.855
W50-W64 Exposure to animate mechanical forces	0.145	0.855
W20-W49 Exposure to inanimate mechanical forces	0.145	0.855
W00-W19 Falls	0.145	0.855
V98-V99 Other and unspecified transport accidents	0.145	0.855
V95-V97 Air and space transport accidents	0.145	0.855
V90-V94 Water transport accidents	0.145	0.855
V80-V89 Other land transport accidents	0.145	0.855
V70-V79 Bus occupant injured in transport accident	0.145	0.855
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.145	0.855
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.145	0.855
V40-V49 Car occupant injured in transport accident	0.145	0.855
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.145	0.855
V20-V29 Motorcycle rider injured in transport accident	0.145	0.855
V10-V19 Pedal cyclist injured in transport accident	0.145	0.855
V01-V09 Pedestrian injured in transport accident	0.145	0.855
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.145	0.855
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.145	0.855
Z85.0 Personal history of malignant neoplasm of digestive organs	0.144	0.855
Z85.9 Personal history of malignant neoplasm, unspecified	0.144	0.855
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.144	0.855
Z85.6 Personal history of leukaemia	0.144	0.855
Z85.5 Personal history of malignant neoplasm of urinary tract	0.144	0.855
Z85.4 Personal history of malignant neoplasm of genital organs	0.144	0.855
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.144	0.855
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.144	0.855
D64 Other anaemias	0.144	0.856
K80 Cholelithiasis	0.144	0.856
G40 Epilepsy	0.144	0.856
I95-I99 Other and unspecified disorders of the circulatory system	0.143	0.857
I70-I79 Diseases of arteries, arterioles and capillaries	0.143	0.857
I60-I69 Cerebrovascular diseases	0.143	0.857
I30-I52 Other forms of heart disease	0.143	0.857
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.143	0.857
I05-I09 Chronic rheumatic heart diseases	0.143	0.857
I00-I02 Acute rheumatic fever	0.143	0.857
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.142	0.858
J17 Pneumonia in diseases classified elsewhere	0.141	0.859
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.141	0.859
J15 Bacterial pneumonia, not elsewhere classified	0.141	0.859
J12 Viral pneumonia, not elsewhere classified	0.141	0.859
J11 Influenza, virus not identified	0.141	0.859
J10 Influenza due to identified influenza virus	0.141	0.859
J14 Pneumonia due to Haemophilus influenzae	0.141	0.859
J13 Pneumonia due to Streptococcus pneumoniae	0.141	0.859
J09 Influenza due to certain identified influenza virus	0.141	0.859
Z29 Need for other prophylactic measures	0.141	0.859
Z28 Immunisation not carried out	0.141	0.859
Z27 Need for immunisation against combinations of infectious diseases	0.141	0.859
Z26 Need for immunisation against other single infectious diseases	0.141	0.859
Z25 Need for immunisation against other single viral diseases	0.141	0.859
Z24 Need for immunisation against certain single viral diseases	0.141	0.859
Z23 Need for immunisation against single bacterial diseases	0.141	0.859
Z22 Carrier of infectious disease	0.141	0.859
Z20 Contact with and exposure to communicable diseases	0.141	0.859
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.141	0.859
Z65 Problems related to other psychosocial circumstances	0.141	0.859
Z64 Problems related to certain psychosocial circumstances	0.141	0.859
Z63 Other problems related to primary support group, including family circumstances	0.141	0.859
Z62 Other problems related to upbringing	0.141	0.859
Z61 Problems related to negative life events in childhood	0.141	0.859
Z60 Problems related to social environment	0.141	0.859
Z59 Problems related to housing and economic circumstances	0.141	0.859
Z58 Problems related to physical environment	0.141	0.859
Z57 Occupational exposure to risk-factors	0.141	0.859
Z56 Problems related to employment and unemployment	0.141	0.859
Z55 Problems related to education and literacy	0.141	0.859
E00-E07 Disorders of thyroid gland	0.141	0.859
K59 Other functional intestinal disorders	0.140	0.860
Z96.9 Presence of functional implant, unspecified	0.140	0.860
Z96.8 Presence of other specified functional implants	0.140	0.860
Z96.7 Presence of other bone and tendon implants	0.140	0.860
Z96.5 Presence of tooth-root and mandibular implants	0.140	0.860
Z96.4 Presence of endocrine implants	0.140	0.860
Z96.3 Presence of artificial larynx	0.140	0.860
Z96.2 Presence of otological and audiological implants	0.140	0.860
Z96.1 Presence of intraocular lens	0.140	0.860
Z96.0 Presence of urogenital implants	0.140	0.860
K40 Inguinal hernia	0.139	0.861
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.139	0.861
Z88.7 Personal history of allergy to serum and vaccine	0.139	0.861
Z88.6 Personal history of allergy to analgesic agent	0.139	0.861
Z88.5 Personal history of allergy to narcotic agent	0.139	0.861
Z88.4 Personal history of allergy to anaesthetic agent	0.139	0.861
Z88.3 Personal history of allergy to other anti-infective agents	0.139	0.861
Z88.2 Personal history of allergy to sulphonamides	0.139	0.861
Z88.1 Personal history of allergy to other antibiotic agents	0.139	0.861
K64 Haemorrhoids and perianal venous thrombosis	0.139	0.861
K61 Abscess of anal and rectal regions	0.139	0.861
K60 Fissure and fistula of anal and rectal regions	0.139	0.861
K56 Paralytic ileus and intestinal obstruction without hernia	0.139	0.861
K55 Vascular disorders of intestine	0.139	0.861
Z88.0 Personal history of allergy to penicillin	0.139	0.861
E50-E64 Other nutritional deficiencies	0.138	0.861
E40-E46 Malnutrition	0.138	0.861
E20-E35 Disorders of other endocrine glands	0.138	0.861
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.138	0.861
R10.3 Pain localised to other parts of lower abdomen	0.138	0.861
J06 Acute upper respiratory infections of multiple and unspecified sites	0.137	0.862
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.137	0.862
J04 Acute laryngitis and tracheitis	0.137	0.862
J03 Acute tonsillitis	0.137	0.862
J02 Acute pharyngitis	0.137	0.862
J01 Acute sinusitis	0.137	0.862
J00 Acute nasopharyngitis [common cold]	0.137	0.862
J39 Other diseases of upper respiratory tract	0.137	0.862
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.137	0.862
J37 Chronic laryngitis and laryngotracheitis	0.137	0.862
J35 Chronic diseases of tonsils and adenoids	0.137	0.862
J34 Other disorders of nose and nasal sinuses	0.137	0.862
J33 Nasal polyp	0.137	0.862
J32 Chronic sinusitis	0.137	0.862
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.137	0.862
J30 Vasomotor and allergic rhinitis	0.137	0.862
J36 Peritonsillar abscess	0.137	0.862
J70 Respiratory conditions due to other external agents	0.137	0.862
J69 Pneumonitis due to solids and liquids	0.137	0.862
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.137	0.862
J67 Hypersensitivity pneumonitis due to organic dust	0.137	0.862
J66 Airway disease due to specific organic dust	0.137	0.862
J63 Pneumoconiosis due to other inorganic dusts	0.137	0.862
J62 Pneumoconiosis due to dust containing silica	0.137	0.862
J65 Pneumoconiosis associated with tuberculosis	0.137	0.862
J64 Unspecified pneumoconiosis	0.137	0.862
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.137	0.862
J60 Coalworker's pneumoconiosis	0.137	0.862
J84 Other interstitial pulmonary diseases	0.137	0.862

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations