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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9446777
log Bayes Factor = 6.12687
Chromosome 6   position 73,581,051  (GRCh37) Explore rs9446777 on Ensembl!
Variant rs9446777 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
M54 Dorsalgia
0.999 0.001 0.000
M54.5 Low back pain
0.997 0.003 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.996 0.004 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.993 0.007 0.000
M54.56 Low back pain (Lumbar region)
0.991 0.009 0.000
Chapter I Certain infectious and parasitic diseases
0.989 0.011 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.989 0.011 0.000
S80-S89 Injuries to the knee and lower leg
0.987 0.013 0.000
S00-S09 Injuries to the head
0.986 0.014 0.000
Chapter II Neoplasms
0.986 0.014 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.985 0.015 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.964 0.036 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.964 0.036 0.000
S82 Fracture of lower leg, including ankle
0.964 0.036 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.958 0.042 0.000
A00-A09 Intestinal infectious diseases
0.957 0.043 0.000
M45-M49 Spondylopathies
0.956 0.044 0.000
S00 Superficial injury of head
0.955 0.045 0.000
M50 Cervical disk disorders
0.941 0.059 0.000
M54.9 Dorsalgia, unspecified
0.938 0.062 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.935 0.065 0.000
M47 Spondylosis
0.931 0.069 0.000
A08 Viral and other specified intestinal infections
0.919 0.081 0.000
Chapter X Diseases of the respiratory system
0.919 0.081 0.000
M47.8 Other spondylosis
0.918 0.082 0.000
J40-J47 Chronic lower respiratory diseases
0.909 0.091 0.000
G62 Other polyneuropathies
0.907 0.093 0.000
M50.1 Cervical disk disorder with radiculopathy
0.907 0.093 0.000
S82.2 Fracture of shaft of tibia
0.897 0.103 0.000
G30-G32 Other degenerative diseases of the nervous system
0.894 0.106 0.000
S06 Intracranial injury
0.891 0.109 0.000
C15-C26 Malignant neoplasms of digestive organs
0.890 0.110 0.000
J47 Bronchiectasis
0.889 0.111 0.000
S82.3 Fracture of lower end of tibia
0.889 0.111 0.000
G56 Mononeuropathies of upper limb
0.888 0.112 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.884 0.116 0.000
M51 Other intervertebral disk disorders
0.881 0.119 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.880 0.120 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.879 0.121 0.000
S00.8 Superficial injury of other parts of head
0.877 0.123 0.000
G62.9 Polyneuropathy, unspecified
0.876 0.124 0.000
D00-D09 In situ neoplasms
0.876 0.124 0.000
A08.4 Viral intestinal infection, unspecified
0.875 0.125 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.874 0.126 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.870 0.130 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.869 0.131 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.866 0.134 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.864 0.136 0.000
A30-A49 Other bacterial diseases
0.862 0.138 0.000
G90-G99 Other disorders of the nervous system
0.857 0.143 0.000
M54.4 Lumbago with sciatica
0.856 0.144 0.000
S00.0 Superficial injury of scalp
0.853 0.147 0.000
C91 Lymphoid leukaemia
0.852 0.147 0.000
M47.86 Other spondylosis (Lumbar region)
0.852 0.148 0.000
S82.20 Fracture of shaft of tibia (closed)
0.849 0.151 0.000
C25 Malignant neoplasm of pancreas
0.848 0.152 0.000
D06 Carcinoma in situ of cervix uteri
0.848 0.152 0.000
X60-X84 Intentional self-harm
0.847 0.153 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.846 0.153 0.000
M47.82 Other spondylosis (Cervical region)
0.845 0.155 0.000
J42 Unspecified chronic bronchitis
0.842 0.158 0.000
S80 Superficial injury of lower leg
0.839 0.161 0.000
C20 Malignant neoplasm of rectum
0.839 0.161 0.000
W20-W49 Exposure to inanimate mechanical forces
0.838 0.162 0.000
S82.30 Fracture of lower end of tibia (closed)
0.835 0.165 0.000
M54.8 Other dorsalgia
0.830 0.169 0.000
M54.59 Low back pain (Site unspecified)
0.830 0.170 0.000
Y86 Sequelae of other accidents
0.829 0.171 0.000
D06.9 Cervix, unspecified
0.828 0.172 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.825 0.175 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.817 0.183 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.817 0.183 0.000
G61 Inflammatory polyneuropathy
0.817 0.183 0.000
C88 Malignant immunoproliferative diseases
0.816 0.184 0.000
S82.1 Fracture of upper end of tibia
0.811 0.189 0.000
M86-M90 Other osteopathies
0.810 0.190 0.000
J40 Bronchitis, not specified as acute or chronic
0.807 0.193 0.000
Chapter XXII Codes for special purposes
0.807 0.193 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.805 0.195 0.000
S86 Injury of muscle and tendon at lower leg level
0.804 0.196 0.000
S70-S79 Injuries to the hip and thigh
0.802 0.198 0.000
C85.1 B-cell lymphoma, unspecified
0.800 0.200 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.799 0.201 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.797 0.203 0.000
S02 Fracture of skull and facial bones
0.797 0.203 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.796 0.204 0.000
V20-V29 Motorcycle rider injured in transport accident
0.795 0.205 0.000
M40-M43 Deforming dorsopathies
0.794 0.206 0.000
B99-B99 Other infectious diseases
0.794 0.206 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.791 0.209 0.000
B65-B83 Helminthiases
0.791 0.209 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.791 0.209 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.789 0.211 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.788 0.212 0.000
M47.2 Other spondylosis with radiculopathy
0.787 0.213 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.787 0.213 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.785 0.215 0.000
S82.5 Fracture of medial malleolus
0.783 0.217 0.000
C25.0 Head of pancreas
0.780 0.220 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.779 0.221 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.775 0.225 0.000
S09 Other and unspecified injuries of head
0.775 0.225 0.000
C81 Hodgkin's disease
0.774 0.226 0.000
M54.50 Low back pain (Multiple sites in spine)
0.771 0.229 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.769 0.231 0.000
C45 Mesothelioma
0.768 0.232 0.000
M91-M94 Chondropathies
0.767 0.232 0.000
G56.2 Lesion of ulnar nerve
0.764 0.236 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.763 0.237 0.000
A80-A89 Viral infections of the central nervous system
0.762 0.238 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.760 0.240 0.000
T79-T79 Certain early complications of trauma
0.760 0.240 0.000
M54.3 Sciatica
0.759 0.241 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.758 0.242 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.758 0.242 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.755 0.245 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.754 0.246 0.000
Y00-Y09 Assault
0.752 0.248 0.000
T36 Poisoning by systemic antibiotics
0.749 0.251 0.000
A02 Other Salmonella infections
0.748 0.252 0.000
W50-W64 Exposure to animate mechanical forces
0.747 0.253 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.744 0.256 0.000
S50-S59 Injuries to the elbow and forearm
0.742 0.258 0.000
M50.3 Other cervical disk degeneration
0.741 0.259 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.259 0.000
C25.9 Pancreas, unspecified
0.740 0.260 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.738 0.262 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.737 0.263 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.736 0.264 0.000
D45 Polycythaemia vera
0.736 0.264 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.266 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.734 0.266 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.733 0.267 0.000
C91.4 Hairy-cell leukaemia
0.732 0.268 0.000
G61.8 Other inflammatory polyneuropathies
0.732 0.268 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.730 0.270 0.000
J30-J39 Other diseases of upper respiratory tract
0.727 0.273 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.727 0.273 0.000
G90 Disorders of autonomic nervous system
0.726 0.274 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.726 0.274 0.000
M50.2 Other cervical disk displacement
0.726 0.274 0.000
G56.0 Carpal tunnel syndrome
0.724 0.276 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.724 0.276 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.724 0.276 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.721 0.279 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.720 0.280 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.719 0.281 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.719 0.281 0.000
M54.57 Low back pain (Lumbosacral region)
0.719 0.281 0.000
M51.2 Other specified intervertebral disk displacement
0.719 0.281 0.000
M48 Other spondylopathies
0.718 0.281 0.000
M51.9 Intervertebral disk disorder, unspecified
0.717 0.283 0.000
G96 Other disorders of central nervous system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.717 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.716 0.284 0.000
Q80-Q89 Other congenital malformations
0.715 0.285 0.000
M54.55 Low back pain (Thoracolumbar region)
0.715 0.285 0.000
M54.54 Low back pain-Thoracic
0.715 0.285 0.000
M54.53 Low back pain-Cervicothoracic
0.715 0.285 0.000
M54.52 Low back pain-Cervical
0.715 0.285 0.000
M54.51 Low back pain-Occipit-atl-axl
0.715 0.285 0.000
G52 Disorders of other cranial nerves
0.714 0.286 0.000
B15-B19 Viral hepatitis
0.713 0.287 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.713 0.287 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.712 0.288 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
G30 Alzheimer's disease
0.710 0.290 0.000
Chapter VIII Diseases of the ear and mastoid process
0.710 0.290 0.000
M54.89 Other dorsalgia (Site unspecified)
0.709 0.291 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.291 0.000
A75-A79 Rickettsioses
0.709 0.291 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.291 0.000
A65-A69 Other spirochaetal diseases
0.709 0.291 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.291 0.000
A15-A19 Tuberculosis
0.709 0.291 0.000
T43.2 Other and unspecified antidepressants
0.708 0.292 0.000
S88 Traumatic amputation of lower leg
0.708 0.292 0.000
S87 Crushing injury of lower leg
0.708 0.292 0.000
S85 Injury of blood vessels at lower leg level
0.708 0.292 0.000
S84 Injury of nerves at lower leg level
0.708 0.292 0.000
S08 Traumatic amputation of part of head
0.707 0.293 0.000
S07 Crushing injury of head
0.707 0.293 0.000
S05 Injury of eye and orbit
0.707 0.293 0.000
S04 Injury of cranial nerves
0.707 0.293 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.707 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.293 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.706 0.293 0.000
C95 Leukaemia of unspecified cell type
0.706 0.293 0.000
C94 Other leukaemias of specified cell type
0.706 0.293 0.000
C93 Monocytic leukaemia
0.706 0.293 0.000
C86 Other specified types of T/NK-cell lymphoma
0.706 0.293 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.706 0.293 0.000
S82.0 Fracture of patella
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.704 0.295 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.703 0.297 0.000
G91 Hydrocephalus
0.703 0.297 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.702 0.298 0.000
C85.0 Lymphosarcoma
0.702 0.298 0.000
B35-B49 Mycoses
0.702 0.298 0.000
S82.10 Fracture of upper end of tibia (closed)
0.702 0.298 0.000
A49 Bacterial infection of unspecified site
0.700 0.300 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.698 0.302 0.000
S06.3 Focal brain injury
0.698 0.302 0.000
G03 Meningitis due to other and unspecified causes
0.697 0.303 0.000
B25-B34 Other viral diseases
0.697 0.303 0.000
C91.9 Lymphoid leukaemia, unspecified
0.697 0.303 0.000
G70-G73 Diseases of myoneural junction and muscle
0.697 0.303 0.000
M54.6 Pain in thoracic spine
0.695 0.304 0.000
S80.9 Superficial injury of lower leg, unspecified
0.695 0.304 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.695 0.305 0.000
M05-M14 Inflammatory polyarthropathies
0.694 0.305 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.692 0.307 0.000
S00.1 Contusion of eyelid and periocular area
0.692 0.308 0.000
S00.3 Superficial injury of nose
0.691 0.309 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.691 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.691 0.309 0.000
Y10-Y34 Event of undetermined intent
0.691 0.309 0.000
X85-X99 Assault
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
X30-X39 Exposure to forces of nature
0.691 0.309 0.000
X20-X29 Contact with venomous animals and plants
0.691 0.309 0.000
X10-X19 Contact with heat and hot substances
0.691 0.309 0.000
X00-X09 Exposure to smoke, fire and flames
0.691 0.309 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.691 0.309 0.000
W75-W84 Other accidental threats to breathing
0.691 0.309 0.000
W65-W74 Accidental drowning and submersion
0.691 0.309 0.000
V98-V99 Other and unspecified transport accidents
0.691 0.309 0.000
V95-V97 Air and space transport accidents
0.691 0.309 0.000
V90-V94 Water transport accidents
0.691 0.309 0.000
V70-V79 Bus occupant injured in transport accident
0.691 0.309 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.691 0.309 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.691 0.309 0.000
V40-V49 Car occupant injured in transport accident
0.691 0.309 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.691 0.309 0.000
V01-V09 Pedestrian injured in transport accident
0.691 0.309 0.000
S82.9 Fracture of lower leg, part unspecified
0.691 0.309 0.000
S82.7 Multiple fractures of lower leg
0.691 0.309 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.691 0.309 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.690 0.310 0.000
A39 Meningococcal infection
0.689 0.311 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.689 0.311 0.000
M46 Other inflammatory spondylopathies
0.689 0.311 0.000
T43.6 Psychostimulants with abuse potential
0.688 0.312 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.688 0.312 0.000
S06.4 Epidural haemorrhage
0.687 0.313 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.687 0.313 0.000
G60 Hereditary and idiopathic neuropathy
0.687 0.313 0.000
G64 Other disorders of peripheral nervous system
0.687 0.313 0.000
A07 Other protozoal intestinal diseases
0.686 0.314 0.000
A06 Amoebiasis
0.686 0.314 0.000
A05 Other bacterial foodborne intoxications
0.686 0.314 0.000
A03 Shigellosis
0.686 0.314 0.000
A01 Typhoid and paratyphoid fevers
0.686 0.314 0.000
A00 Cholera
0.686 0.314 0.000
M49 Spondylopathies in diseases classified elsewhere
0.686 0.314 0.000
M47.89 Other spondylosis (Site unspecified)
0.686 0.314 0.000
S00.5 Superficial injury of lip and oral cavity
0.685 0.315 0.000
S00.4 Superficial injury of ear
0.685 0.315 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.685 0.315 0.000
G54 Nerve root and plexus disorders
0.684 0.316 0.000
W22 Striking against or struck by other objects
0.682 0.318 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.680 0.320 0.000
S06.2 Diffuse brain injury
0.680 0.320 0.000
S00.7 Multiple superficial injuries of head
0.680 0.320 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.679 0.321 0.000
S82.6 Fracture of lateral malleolus
0.678 0.322 0.000
S60-S69 Injuries to the wrist and hand
0.678 0.322 0.000
C91.0 Acute lymphoblastic leukaemia
0.677 0.323 0.000
J09-J18 Influenza and pneumonia
0.676 0.324 0.000
S02.0 Fracture of vault of skull
0.675 0.325 0.000
M50.9 Cervical disk disorder, unspecified
0.674 0.326 0.000
M50.8 Other cervical disk disorders
0.674 0.326 0.000
S81 Open wound of lower leg
0.674 0.326 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.673 0.327 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.673 0.327 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.673 0.327 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.673 0.327 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.673 0.327 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.673 0.327 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.673 0.327 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.673 0.327 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.672 0.327 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.672 0.328 0.000
J43 Emphysema
0.671 0.329 0.000
G51 Facial nerve disorders
0.671 0.329 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.670 0.330 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.670 0.330 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.670 0.330 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.670 0.330 0.000
T90 Sequelae of injuries of head
0.670 0.330 0.000
M65-M68 Disorders of synovium and tendon
0.669 0.331 0.000
M20-M25 Other joint disorders
0.669 0.331 0.000
S90-S99 Injuries to the ankle and foot
0.668 0.332 0.000
M53 Other dorsopathies, not elsewhere classified
0.668 0.332 0.000
S70 Superficial injury of hip and thigh
0.667 0.332 0.000
M47.1 Other spondylosis with myelopathy
0.667 0.333 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.667 0.333 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.666 0.334 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.665 0.335 0.000
C83.1 Small cleaved cell (diffuse)
0.664 0.336 0.000
S20-S29 Injuries to the thorax
0.664 0.336 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.664 0.336 0.000
S89 Other and unspecified injuries of lower leg
0.663 0.337 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.663 0.337 0.000
S02.1 Fracture of base of skull
0.662 0.338 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.662 0.338 0.000
Y88 Sequelae of surgical and medical care as external cause
0.662 0.338 0.000
C92 Myeloid leukaemia
0.661 0.339 0.000
Q60-Q64 Congenital malformations of the urinary system
0.661 0.339 0.000
A08.5 Other specified intestinal infections
0.659 0.341 0.000
A08.3 Other viral enteritis
0.659 0.341 0.000
A08.2 Adenoviral enteritis
0.659 0.341 0.000
A08.0 Rotaviral enteritis
0.659 0.341 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.659 0.341 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.658 0.341 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.658 0.341 0.000
M47.84 Other spondylosis (Thoracic region)
0.658 0.341 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.658 0.341 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.658 0.341 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.658 0.342 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.657 0.343 0.000
W20 Struck by thrown, projected or falling object
0.655 0.344 0.000
J46 Status asthmaticus
0.654 0.346 0.000
B99 Other and unspecified infectious diseases
0.654 0.346 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.654 0.346 0.000
S82.50 Fracture of medial malleolus (closed)
0.654 0.346 0.000
G53.0 Postzoster neuralgia
0.653 0.347 0.000
S80.8 Other superficial injuries of lower leg
0.653 0.347 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.652 0.348 0.000
J41 Simple and mucopurulent chronic bronchitis
0.652 0.348 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.652 0.348 0.000
G50 Disorders of trigeminal nerve
0.651 0.349 0.000
M89 Other disorders of bone
0.651 0.349 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.651 0.349 0.000
G62.2 Polyneuropathy due to other toxic agents
0.650 0.350 0.000
G62.1 Alcoholic polyneuropathy
0.650 0.350 0.000
G62.0 Drug-induced polyneuropathy
0.650 0.350 0.000
B80 Enterobiasis
0.650 0.350 0.000
A40 Streptococcal septicaemia
0.649 0.351 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.648 0.352 0.000
C81.1 Nodular sclerosis
0.647 0.353 0.000
M80-M85 Disorders of bone density and structure
0.647 0.353 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.647 0.353 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.646 0.354 0.000
J00-J06 Acute upper respiratory infections
0.646 0.354 0.000
G56.8 Other mononeuropathies of upper limb
0.645 0.355 0.000
M51.8 Other specified intervertebral disk disorders
0.645 0.355 0.000
S82.21 Fracture of shaft of tibia (open)
0.643 0.357 0.000
M88 Paget's disease of bone [osteitis deformans]
0.642 0.357 0.000
S12 Fracture of neck
0.642 0.357 0.000
G31.0 Circumscribed brain atrophy
0.642 0.358 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.642 0.358 0.000
V10-V19 Pedal cyclist injured in transport accident
0.641 0.359 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.641 0.359 0.000
C83.3 Large cell (diffuse)
0.641 0.359 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.640 0.360 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.639 0.360 0.000
G31.2 Degeneration of nervous system due to alcohol
0.639 0.361 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.639 0.361 0.000
S06.9 Intracranial injury, unspecified
0.639 0.361 0.000
S06.8 Other intracranial injuries
0.639 0.361 0.000
S06.7 Intracranial injury with prolonged coma
0.639 0.361 0.000
S06.1 Traumatic cerebral oedema
0.639 0.361 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.638 0.362 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.638 0.362 0.000
C17 Malignant neoplasm of small intestine
0.638 0.362 0.000
C23 Malignant neoplasm of gallbladder
0.638 0.362 0.000
S82.31 Fracture of lower end of tibia (open)
0.637 0.363 0.000
D03 Melanoma in situ
0.637 0.363 0.000
W25 Contact with sharp glass
0.636 0.363 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.636 0.363 0.000
G56.4 Causalgia
0.636 0.363 0.000
G56.3 Lesion of radial nerve
0.636 0.363 0.000
G56.1 Other lesions of median nerve
0.636 0.363 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.634 0.366 0.000
C46 Kaposi's sarcoma
0.634 0.366 0.000
Q00-Q07 Congenital malformations of the nervous system
0.633 0.367 0.000
M51.3 Other specified intervertebral disk degeneration
0.632 0.368 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.632 0.368 0.000
M51.4 Schmorl's nodes
0.632 0.368 0.000
M54.2 Cervicalgia
0.631 0.368 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.631 0.369 0.000
Q35-Q37 Cleft lip and cleft palate
0.631 0.369 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.631 0.369 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.631 0.369 0.000
Y89 Sequelae of other external causes
0.630 0.370 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.630 0.370 0.000
A46 Erysipelas
0.629 0.371 0.000
A41 Other septicaemia
0.629 0.371 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.628 0.372 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.628 0.372 0.000
C45.7 Mesothelioma of other sites
0.627 0.372 0.000
X62.9 Unspecified place
0.627 0.373 0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.626 0.374 0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.626 0.374 0.000
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.626 0.374 0.000
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.626 0.374 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.624 0.376 0.000
G31.8 Other specified degenerative diseases of nervous system
0.624 0.376 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.624 0.376 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.624 0.376 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.624 0.376 0.000
G00 Bacterial meningitis, not elsewhere classified
0.624 0.376 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.624 0.376 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.624 0.376 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.624 0.376 0.000
S09.9 Unspecified injury of head
0.624 0.376 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.623 0.377 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.623 0.377 0.000
C21 Malignant neoplasm of anus and anal canal
0.622 0.378 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.622 0.378 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.622 0.378 0.000
C45.0 Mesothelioma of pleura
0.620 0.379 0.000
S00.9 Superficial injury of head, part unspecified
0.620 0.380 0.000
A04 Other bacterial intestinal infections
0.620 0.380 0.000
S72 Fracture of femur
0.618 0.381 0.000
X58 Exposure to other specified factors
0.618 0.382 0.000
A48 Other bacterial diseases, not elsewhere classified
0.618 0.382 0.000
A44 Bartonellosis
0.618 0.382 0.000
A43 Nocardiosis
0.618 0.382 0.000
A42 Actinomycosis
0.618 0.382 0.000
A37 Whooping cough
0.618 0.382 0.000
A36 Diphtheria
0.618 0.382 0.000
A32 Listeriosis
0.618 0.382 0.000
A31 Infection due to other mycobacteria
0.618 0.382 0.000
A30 Leprosy [Hansen's disease]
0.618 0.382 0.000
A38 Scarlet fever
0.618 0.382 0.000
A35 Other tetanus
0.618 0.382 0.000
A34 Obstetrical tetanus
0.618 0.382 0.000
A33 Tetanus neonatorum
0.618 0.382 0.000
W21 Striking against or struck by sports equipment
0.618 0.382 0.000
T98 Sequelae of other and unspecified effects of external causes
0.617 0.383 0.000
T36.0 Penicillins
0.616 0.384 0.000
M43 Other deforming dorsopathies
0.616 0.384 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.614 0.386 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.614 0.386 0.000
G92 Toxic encephalopathy
0.614 0.386 0.000
T20 Burn and corrosion of head and neck
0.614 0.386 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.614 0.386 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.614 0.386 0.000
M54.44 Lumbago with sciatica-Thoracic
0.614 0.386 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.614 0.386 0.000
M54.42 Lumbago with sciatica-Cervical
0.614 0.386 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.614 0.386 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.614 0.386 0.000
T91 Sequelae of injuries of neck and trunk
0.613 0.386 0.000
S06.5 Traumatic subdural haemorrhage
0.613 0.387 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.611 0.389 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.611 0.389 0.000
C91.7 Other lymphoid leukaemia
0.611 0.389 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.611 0.389 0.000
C91.5 Adult T-cell leukaemia
0.611 0.389 0.000
C91.3 Prolymphocytic leukaemia
0.611 0.389 0.000
C91.2 Subacute lymphocytic leukaemia
0.611 0.389 0.000
G37 Other demyelinating diseases of central nervous system
0.611 0.389 0.000
M54.36 Sciatica (Lumbar region)
0.609 0.391 0.000
C01 Malignant neoplasm of base of tongue
0.609 0.391 0.000
M41 Scoliosis
0.608 0.391 0.000
C25.8 Overlapping lesion of pancreas
0.608 0.392 0.000
C25.7 Other parts of pancreas
0.608 0.392 0.000
C25.4 Endocrine pancreas
0.608 0.392 0.000
C25.3 Pancreatic duct
0.608 0.392 0.000
C25.2 Tail of pancreas
0.608 0.392 0.000
C25.1 Body of pancreas
0.608 0.392 0.000
Q65 Congenital deformities of hip
0.608 0.392 0.000
D06.7 Other parts of cervix
0.608 0.392 0.000
D06.1 Exocervix
0.608 0.392 0.000
D06.0 Endocervix
0.608 0.392 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.608 0.392 0.000
X84 Intentional self-harm by unspecified means
0.607 0.393 0.000
X83 Intentional self-harm by other specified means
0.607 0.393 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.607 0.393 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.607 0.393 0.000
X80 Intentional self-harm by jumping from a high place
0.607 0.393 0.000
X79 Intentional self-harm by blunt object
0.607 0.393 0.000
X78 Intentional self-harm by sharp object
0.607 0.393 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.607 0.393 0.000
X76 Intentional self-harm by smoke, fire and flames
0.607 0.393 0.000
X75 Intentional self-harm by explosive material
0.607 0.393 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.607 0.393 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.607 0.393 0.000
X72 Intentional self-harm by handgun discharge
0.607 0.393 0.000
X71 Intentional self-harm by drowning and submersion
0.607 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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