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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9451846
log Bayes Factor = 18.5341
Chromosome 6   position 65,219,452  (GRCh37) Explore rs9451846 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
O60-O75 Complications of labour and delivery
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.996 0.004 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.996 0.004 0.000
R07 Pain in throat and chest
0.995 0.005 0.000
R07.4 Chest pain, unspecified
0.994 0.006 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.991 0.009 0.000
I25.2 Old myocardial infarction
0.990 0.010 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.987 0.013 0.000
E83 Disorders of mineral metabolism
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.985 0.015 0.000
E10 Insulin-dependent diabetes mellitus
0.981 0.019 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.979 0.021 0.000
E78.0 Pure hypercholesterolaemia
0.979 0.021 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
E83.5 Disorders of calcium metabolism
0.969 0.031 0.000
I60-I69 Cerebrovascular diseases
0.966 0.034 0.000
F30-F39 Mood [affective] disorders
0.960 0.040 0.000
I20 Angina pectoris
0.956 0.044 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.954 0.046 0.000
I21 Acute myocardial infarction
0.951 0.049 0.000
M50-M54 Other dorsopathies
0.949 0.051 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.946 0.054 0.000
S60-S69 Injuries to the wrist and hand
0.946 0.054 0.000
E11 Non-insulin-dependent diabetes mellitus
0.942 0.058 0.000
E10.9 Without complications
0.940 0.060 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.936 0.064 0.000
R07.3 Other chest pain
0.931 0.069 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.931 0.069 0.000
F31 Bipolar affective disorder
0.930 0.070 0.000
I21.9 Acute myocardial infarction, unspecified
0.930 0.070 0.000
S80-S89 Injuries to the knee and lower leg
0.923 0.077 0.000
I20.9 Angina pectoris, unspecified
0.920 0.080 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.916 0.084 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.915 0.085 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.914 0.086 0.000
R50-R69 General symptoms and signs
0.914 0.086 0.000
M54 Dorsalgia
0.912 0.088 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.905 0.095 0.000
M80-M85 Disorders of bone density and structure
0.904 0.096 0.000
Chapter I Certain infectious and parasitic diseases
0.902 0.098 0.000
Chapter XXI Factors influencing health status and contact with health services
0.900 0.100 0.000
Chapter VI Diseases of the nervous system
0.899 0.101 0.000
I67 Other cerebrovascular diseases
0.896 0.104 0.000
E11.9 Without complications
0.895 0.105 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.891 0.109 0.000
F31.9 Bipolar affective disorder, unspecified
0.885 0.115 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.885 0.115 0.000
O70 Perineal laceration during delivery
0.884 0.116 0.000
I73 Other peripheral vascular diseases
0.883 0.117 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.879 0.121 0.000
S00-S09 Injuries to the head
0.877 0.123 0.000
E83.4 Disorders of magnesium metabolism
0.875 0.125 0.000
O63 Long labour
0.867 0.133 0.000
Z50 Care involving use of rehabilitation procedures
0.863 0.137 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.862 0.138 0.000
M15-M19 Arthrosis
0.856 0.144 0.000
R69 Unknown and unspecified causes of morbidity
0.856 0.144 0.000
I95 Hypotension
0.852 0.148 0.000
Z50.1 Other physical therapy
0.850 0.150 0.000
O72 Postpartum haemorrhage
0.848 0.152 0.000
F33 Recurrent depressive disorder
0.848 0.152 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.843 0.157 0.000
I67.9 Cerebrovascular disease, unspecified
0.843 0.157 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.841 0.159 0.000
O42 Premature rupture of membranes
0.835 0.165 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.831 0.169 0.000
I63 Cerebral infarction
0.830 0.170 0.000
I25.1 Atherosclerotic heart disease
0.830 0.170 0.000
I69 Sequelae of cerebrovascular disease
0.828 0.172 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.826 0.174 0.000
I22 Subsequent myocardial infarction
0.825 0.175 0.000
S61 Open wound of wrist and hand
0.822 0.178 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.820 0.180 0.000
I73.9 Peripheral vascular disease, unspecified
0.818 0.182 0.000
O70.0 First degree perineal laceration during delivery
0.818 0.182 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.817 0.183 0.000
R01 Cardiac murmurs and other cardiac sounds
0.813 0.187 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.812 0.188 0.000
R59 Enlarged lymph nodes
0.810 0.190 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.808 0.192 0.000
E20-E35 Disorders of other endocrine glands
0.806 0.194 0.000
I95.9 Hypotension, unspecified
0.806 0.194 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.806 0.194 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.804 0.196 0.000
I20.0 Unstable angina
0.803 0.197 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.803 0.197 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.799 0.201 0.000
Z45 Adjustment and management of implanted device
0.798 0.202 0.000
E10.4 With neurological complications
0.797 0.203 0.000
E11.3 With ophthalmic complications
0.796 0.204 0.000
O16 Unspecified maternal hypertension
0.793 0.207 0.000
O66 Other obstructed labour
0.791 0.208 0.000
R41.0 Disorientation, unspecified
0.791 0.209 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.790 0.210 0.000
S70-S79 Injuries to the hip and thigh
0.790 0.210 0.000
S10-S19 Injuries to the neck
0.789 0.211 0.000
Chapter VII Diseases of the eye and adnexa
0.789 0.211 0.000
I71 Aortic aneurysm and dissection
0.788 0.212 0.000
S83.2 Tear of meniscus, current
0.788 0.212 0.000
E10.1 With ketoacidosis
0.785 0.214 0.000
Chapter XXII Codes for special purposes
0.784 0.216 0.000
O42.9 Premature rupture of membranes, unspecified
0.784 0.216 0.000
R23 Other skin changes
0.783 0.217 0.000
M54.5 Low back pain
0.782 0.218 0.000
M54.2 Cervicalgia
0.779 0.221 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.778 0.222 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.778 0.222 0.000
E10.3 With ophthalmic complications
0.777 0.223 0.000
A30-A49 Other bacterial diseases
0.776 0.224 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.774 0.225 0.000
M05-M14 Inflammatory polyarthropathies
0.774 0.226 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.773 0.227 0.000
E10.5 With peripheral circulatory complications
0.773 0.227 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.773 0.227 0.000
O48 Prolonged pregnancy
0.773 0.227 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.772 0.228 0.000
S90-S99 Injuries to the ankle and foot
0.771 0.229 0.000
M54.4 Lumbago with sciatica
0.770 0.230 0.000
S40-S49 Injuries to the shoulder and upper arm
0.769 0.231 0.000
M65-M68 Disorders of synovium and tendon
0.766 0.234 0.000
M40-M43 Deforming dorsopathies
0.766 0.234 0.000
M80 Osteoporosis with pathological fracture
0.765 0.235 0.000
O62 Abnormalities of forces of labour
0.765 0.235 0.000
M17 Gonarthrosis [arthrosis of knee]
0.764 0.236 0.000
S62 Fracture at wrist and hand level
0.763 0.237 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.763 0.237 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.763 0.237 0.000
M16 Coxarthrosis [arthrosis of hip]
0.762 0.238 0.000
M84 Disorders of continuity of bone
0.761 0.239 0.000
R06 Abnormalities of breathing
0.759 0.241 0.000
I62 Other nontraumatic intracranial haemorrhage
0.758 0.242 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.757 0.243 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.757 0.243 0.000
I77 Other disorders of arteries and arterioles
0.755 0.245 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.755 0.245 0.000
O00-O08 Pregnancy with abortive outcome
0.754 0.246 0.000
S89 Other and unspecified injuries of lower leg
0.753 0.247 0.000
S61.8 Open wound of other parts of wrist and hand
0.753 0.247 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.752 0.248 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.749 0.251 0.000
R56 Convulsions, not elsewhere classified
0.749 0.251 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.746 0.254 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.746 0.254 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.745 0.255 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.744 0.256 0.000
I25.5 Ischaemic cardiomyopathy
0.742 0.258 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.741 0.259 0.000
E40-E46 Malnutrition
0.739 0.261 0.000
S01 Open wound of head
0.738 0.262 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.736 0.264 0.000
R60 Oedema, not elsewhere classified
0.733 0.267 0.000
I67.8 Other specified cerebrovascular diseases
0.733 0.267 0.000
I80 Phlebitis and thrombophlebitis
0.732 0.268 0.000
O43 Placental disorders
0.731 0.269 0.000
O72.1 Other immediate postpartum haemorrhage
0.731 0.269 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.731 0.269 0.000
F99-F99 Unspecified mental disorder
0.729 0.271 0.000
F60-F69 Disorders of adult personality and behaviour
0.729 0.271 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.726 0.274 0.000
R53 Malaise and fatigue
0.726 0.274 0.000
R07.0 Pain in throat
0.726 0.274 0.000
Z45.8 Adjustment and management of other implanted devices
0.725 0.275 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.725 0.275 0.000
R40 Somnolence, stupor and coma
0.723 0.277 0.000
R50 Fever of unknown origin
0.723 0.277 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.723 0.277 0.000
E50-E64 Other nutritional deficiencies
0.722 0.278 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.722 0.278 0.000
M50 Cervical disk disorders
0.722 0.278 0.000
Z50.8 Care involving use of rehabilitation procedures
0.722 0.278 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.721 0.279 0.000
I78 Diseases of capillaries
0.721 0.279 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.721 0.279 0.000
A80-A89 Viral infections of the central nervous system
0.720 0.279 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.720 0.280 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.720 0.280 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.719 0.281 0.000
O63.1 Prolonged second stage (of labour)
0.719 0.281 0.000
M86-M90 Other osteopathies
0.719 0.281 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
E78.5 Hyperlipidaemia, unspecified
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
O74 Complications of anaesthesia during labour and delivery
0.716 0.284 0.000
O73 Retained placenta and membranes, without haemorrhage
0.716 0.284 0.000
O71 Other obstetric trauma
0.716 0.284 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.716 0.284 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.716 0.284 0.000
O61 Failed induction of labour
0.716 0.284 0.000
O60 Preterm delivery
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
M51 Other intervertebral disk disorders
0.716 0.284 0.000
E88 Other metabolic disorders
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.715 0.285 0.000
S64 Injury of nerves at wrist and hand level
0.715 0.285 0.000
E13 Other specified diabetes mellitus
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.286 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.714 0.286 0.000
E89.0 Postprocedural hypothyroidism
0.712 0.288 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.711 0.289 0.000
M54.59 Low back pain (Site unspecified)
0.711 0.289 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.711 0.289 0.000
M85 Other disorders of bone density and structure
0.710 0.289 0.000
F32 Depressive episode
0.710 0.290 0.000
O63.0 Prolonged first stage (of labour)
0.709 0.291 0.000
Z39 Postpartum care and examination
0.709 0.291 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.708 0.292 0.000
M54.1 Radiculopathy
0.708 0.292 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.708 0.292 0.000
E78.8 Other disorders of lipoprotein metabolism
0.708 0.292 0.000
E78.6 Lipoprotein deficiency
0.708 0.292 0.000
E78.4 Other hyperlipidaemia
0.708 0.292 0.000
E78.3 Hyperchylomicronaemia
0.708 0.292 0.000
E78.2 Mixed hyperlipidaemia
0.708 0.292 0.000
E78.1 Pure hyperglyceridaemia
0.708 0.292 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.707 0.293 0.000
E83.8 Other disorders of mineral metabolism
0.707 0.293 0.000
E83.3 Disorders of phosphorus metabolism
0.707 0.293 0.000
E83.2 Disorders of zinc metabolism
0.707 0.293 0.000
E83.0 Disorders of copper metabolism
0.707 0.293 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.706 0.294 0.000
S67 Crushing injury of wrist and hand
0.706 0.294 0.000
M91-M94 Chondropathies
0.706 0.294 0.000
M60-M63 Disorders of muscles
0.706 0.294 0.000
M00-M03 Infectious arthropathies
0.706 0.294 0.000
F33.9 Recurrent depressive disorder, unspecified
0.706 0.294 0.000
O30 Multiple gestation
0.706 0.294 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.705 0.295 0.000
S20-S29 Injuries to the thorax
0.705 0.295 0.000
M54.6 Pain in thoracic spine
0.705 0.295 0.000
R59.0 Localised enlarged lymph nodes
0.704 0.296 0.000
R20 Disturbances of skin sensation
0.704 0.296 0.000
E10.8 With unspecified complications
0.703 0.297 0.000
E10.7 With multiple complications
0.703 0.297 0.000
E10.6 With other specified complications
0.703 0.297 0.000
E10.2 With renal complications
0.703 0.297 0.000
E10.0 With coma
0.703 0.297 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.703 0.297 0.000
S80 Superficial injury of lower leg
0.703 0.297 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.702 0.298 0.000
S81 Open wound of lower leg
0.702 0.298 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.701 0.299 0.000
Chapter XIV Diseases of the genitourinary system
0.701 0.299 0.000
R44.3 Hallucinations, unspecified
0.700 0.300 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F80-F89 Disorders of psychological development
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
M16.9 Coxarthrosis, unspecified
0.700 0.300 0.000
I21.4 Acute subendocardial myocardial infarction
0.698 0.302 0.000
Z36 Antenatal screening
0.697 0.303 0.000
B25-B34 Other viral diseases
0.695 0.305 0.000
I61 Intracerebral haemorrhage
0.695 0.305 0.000
E14 Unspecified diabetes mellitus
0.695 0.305 0.000
S68 Traumatic amputation of wrist and hand
0.694 0.305 0.000
M53 Other dorsopathies, not elsewhere classified
0.694 0.306 0.000
S69 Other and unspecified injuries of wrist and hand
0.693 0.307 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.692 0.308 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.692 0.308 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.691 0.309 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.691 0.309 0.000
G30-G32 Other degenerative diseases of the nervous system
0.691 0.309 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.691 0.309 0.000
G20-G26 Extrapyramidal and movement disorders
0.690 0.310 0.000
T66-T78 Other and unspecified effects of external causes
0.689 0.310 0.000
I73.0 Raynaud's syndrome
0.689 0.311 0.000
S06 Intracranial injury
0.689 0.311 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.689 0.311 0.000
F38 Other mood [affective] disorders
0.688 0.312 0.000
F34 Persistent mood [affective] disorders
0.688 0.312 0.000
F30 Manic episode
0.688 0.312 0.000
F39 Unspecified mood [affective] disorder
0.688 0.312 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.688 0.312 0.000
I20.1 Angina pectoris with documented spasm
0.687 0.312 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.686 0.314 0.000
R07.1 Chest pain on breathing
0.685 0.314 0.000
Z41 Procedures for purposes other than remedying health state
0.685 0.315 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.684 0.316 0.000
I72 Other aneurysm
0.684 0.316 0.000
I70 Atherosclerosis
0.684 0.316 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.683 0.317 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.683 0.317 0.000
R01.1 Cardiac murmur, unspecified
0.682 0.318 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.682 0.318 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.682 0.318 0.000
S02 Fracture of skull and facial bones
0.682 0.318 0.000
R82 Other abnormal findings in urine
0.681 0.319 0.000
R22.1 Localised swelling, mass and lump, neck
0.680 0.320 0.000
M17.0 Primary gonarthrosis, bilateral
0.680 0.320 0.000
G81 Hemiplegia
0.679 0.321 0.000
S65 Injury of blood vessels at wrist and hand level
0.678 0.322 0.000
S60 Superficial injury of wrist and hand
0.678 0.322 0.000
Z50.2 Alcohol rehabilitation
0.678 0.322 0.000
O70.2 Third degree perineal laceration during delivery
0.677 0.323 0.000
O80-O84 Delivery
0.676 0.324 0.000
R02 Gangrene, not elsewhere classified
0.676 0.324 0.000
E11.8 With unspecified complications
0.675 0.325 0.000
E11.7 With multiple complications
0.675 0.325 0.000
E11.6 With other specified complications
0.675 0.325 0.000
E11.1 With ketoacidosis
0.675 0.325 0.000
E11.0 With coma
0.675 0.325 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.674 0.326 0.000
E29 Testicular dysfunction
0.672 0.328 0.000
O45 Premature separation of placenta [abruptio placentae]
0.671 0.329 0.000
O44 Placenta praevia
0.671 0.329 0.000
O41 Other disorders of amniotic fluid and membranes
0.671 0.329 0.000
O33 Maternal care for known or suspected disproportion
0.671 0.329 0.000
O31 Complications specific to multiple gestation
0.671 0.329 0.000
O40 Polyhydramnios
0.671 0.329 0.000
S00 Superficial injury of head
0.671 0.329 0.000
B35-B49 Mycoses
0.670 0.330 0.000
E65-E68 Obesity and other hyperalimentation
0.669 0.330 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.669 0.331 0.000
F31.8 Other bipolar affective disorders
0.667 0.333 0.000
F31.7 Bipolar affective disorder, currently in remission
0.667 0.333 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.667 0.333 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.667 0.333 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.667 0.333 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.667 0.333 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.667 0.333 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.667 0.333 0.000
Z34 Supervision of normal pregnancy
0.667 0.333 0.000
N10-N16 Renal tubulo-interstitial diseases
0.666 0.334 0.000
I81 Portal vein thrombosis
0.665 0.335 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.665 0.335 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.665 0.335 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.664 0.335 0.000
S88 Traumatic amputation of lower leg
0.661 0.338 0.000
S87 Crushing injury of lower leg
0.661 0.338 0.000
S86 Injury of muscle and tendon at lower leg level
0.661 0.338 0.000
S85 Injury of blood vessels at lower leg level
0.661 0.338 0.000
S84 Injury of nerves at lower leg level
0.661 0.338 0.000
M45-M49 Spondylopathies
0.661 0.338 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.661 0.339 0.000
A00-A09 Intestinal infectious diseases
0.660 0.340 0.000
Z52 Donors of organs and tissues
0.659 0.341 0.000
R45 Symptoms and signs involving emotional state
0.658 0.341 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.658 0.342 0.000
E11.2 With renal complications
0.657 0.343 0.000
R46 Symptoms and signs involving appearance and behaviour
0.657 0.343 0.000
R43 Disturbances of smell and taste
0.657 0.343 0.000
R23.8 Other and unspecified skin changes
0.656 0.344 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.656 0.344 0.000
I99 Other and unspecified disorders of circulatory system
0.656 0.344 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.656 0.344 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.656 0.344 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.656 0.344 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.656 0.344 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.656 0.344 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.656 0.344 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.656 0.344 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.656 0.344 0.000
T36 Poisoning by systemic antibiotics
0.656 0.344 0.000
M81 Osteoporosis without pathological fracture
0.656 0.344 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.655 0.345 0.000
R68 Other general symptoms and signs
0.655 0.345 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.655 0.345 0.000
R62 Lack of expected normal physiological development
0.655 0.345 0.000
R57 Shock, not elsewhere classified
0.655 0.345 0.000
R64 Cachexia
0.655 0.345 0.000
R58 Haemorrhage, not elsewhere classified
0.655 0.345 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.655 0.345 0.000
M54.8 Other dorsalgia
0.654 0.346 0.000
M54.0 Panniculitis affecting regions of neck and back
0.654 0.346 0.000
S62.3 Fracture of other metacarpal bone
0.654 0.346 0.000
M54.22 Cervicalgia (Cervical region)
0.653 0.347 0.000
A41 Other septicaemia
0.653 0.347 0.000
I86 Varicose veins of other sites
0.652 0.348 0.000
Z54 Convalescence
0.651 0.349 0.000
M54.3 Sciatica
0.650 0.349 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.650 0.350 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.650 0.350 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.649 0.351 0.000
M83 Adult osteomalacia
0.648 0.351 0.000
M82 Osteoporosis in diseases classified elsewhere
0.648 0.351 0.000
E11.5 With peripheral circulatory complications
0.647 0.352 0.000
I26 Pulmonary embolism
0.647 0.353 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.647 0.353 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.647 0.353 0.000
I30-I52 Other forms of heart disease
0.647 0.353 0.000
B99-B99 Other infectious diseases
0.646 0.353 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.646 0.353 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.646 0.353 0.000
B65-B83 Helminthiases
0.646 0.353 0.000
B50-B64 Protozoal diseases
0.646 0.353 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.646 0.353 0.000
B15-B19 Viral hepatitis
0.646 0.353 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.646 0.353 0.000
A75-A79 Rickettsioses
0.646 0.353 0.000
A70-A74 Other diseases caused by chlamydiae
0.646 0.353 0.000
A65-A69 Other spirochaetal diseases
0.646 0.353 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.646 0.353 0.000
A20-A28 Certain zoonotic bacterial diseases
0.646 0.353 0.000
A15-A19 Tuberculosis
0.646 0.353 0.000
S01.8 Open wound of other parts of head
0.646 0.353 0.000
M65 Synovitis and tenosynovitis
0.646 0.354 0.000
R59.9 Enlarged lymph nodes, unspecified
0.646 0.354 0.000
M17.9 Gonarthrosis, unspecified
0.645 0.355 0.000
G70-G73 Diseases of myoneural junction and muscle
0.644 0.355 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.644 0.355 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.644 0.355 0.000
Z45.2 Adjustment and management of vascular access device
0.644 0.356 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.643 0.357 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.642 0.358 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.642 0.358 0.000
I67.5 Moyamoya disease
0.642 0.358 0.000
I67.4 Hypertensive encephalopathy
0.642 0.358 0.000
I67.3 Progressive vascular leukoencephalopathy
0.642 0.358 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.642 0.358 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.642 0.358 0.000
Z39.0 Care and examination immediately after delivery
0.642 0.358 0.000
I89.0 Lymphoedema, not elsewhere classified
0.641 0.359 0.000
I60 Subarachnoid haemorrhage
0.639 0.361 0.000
S10 Superficial injury of neck
0.639 0.361 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.639 0.361 0.000
O97 Death from sequelae of direct obstetric causes
0.639 0.361 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.639 0.361 0.000
O95 Obstetric death of unspecified cause
0.639 0.361 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.639 0.361 0.000
N17-N19 Renal failure
0.638 0.362 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.638 0.362 0.000
B95-B98 Bacterial, viral and other infectious agents
0.638 0.362 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.637 0.362 0.000
I95.2 Hypotension due to drugs
0.637 0.363 0.000
M06 Other rheumatoid arthritis
0.636 0.364 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.636 0.364 0.000
O47 False labour
0.635 0.365 0.000
O15 Eclampsia
0.634 0.366 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.634 0.366 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.634 0.366 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.634 0.366 0.000
O70.9 Perineal laceration during delivery, unspecified
0.634 0.366 0.000
O70.3 Fourth degree perineal laceration during delivery
0.634 0.366 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.634 0.366 0.000
I73.8 Other specified peripheral vascular diseases
0.633 0.366 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.633 0.366 0.000
I74 Arterial embolism and thrombosis
0.633 0.367 0.000
Z32 Pregnancy examination and test
0.633 0.367 0.000
R22.0 Localised swelling, mass and lump, head
0.633 0.367 0.000
S89.9 Unspecified injury of lower leg
0.632 0.368 0.000
G90-G99 Other disorders of the nervous system
0.632 0.368 0.000
M16.7 Other secondary coxarthrosis
0.631 0.369 0.000
H30-H36 Disorders of choroid and retina
0.631 0.369 0.000
R56.8 Other and unspecified convulsions
0.631 0.369 0.000
O32.2 Maternal care for transverse and oblique lie
0.630 0.370 0.000
H55-H59 Other disorders of eye and adnexa
0.629 0.371 0.000
I67.2 Cerebral atherosclerosis
0.629 0.371 0.000
R23.2 Flushing
0.629 0.371 0.000
S08 Traumatic amputation of part of head
0.628 0.371 0.000
S07 Crushing injury of head
0.628 0.371 0.000
S05 Injury of eye and orbit
0.628 0.371 0.000
S04 Injury of cranial nerves
0.628 0.371 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.628 0.371 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.628 0.372 0.000
M54.9 Dorsalgia, unspecified
0.626 0.374 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.625 0.375 0.000
Z50.0 Cardiac rehabilitation
0.625 0.375 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.625 0.375 0.000
R61 Hyperhidrosis
0.625 0.375 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.625 0.375 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.624 0.376 0.000
R06.0 Dyspnoea
0.624 0.376 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.622 0.378 0.000
Chapter VIII Diseases of the ear and mastoid process
0.622 0.378 0.000
O63.9 Long labour, unspecified
0.621 0.378 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.621 0.378 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.621 0.379 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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