TreeWAS – Variant ID: rs9461741

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.821	0.179
S60-S69 Injuries to the wrist and hand	0.804	0.196
# Top node	0.800	0.200
Chapter II Neoplasms	0.800	0.200
S61 Open wound of wrist and hand	0.789	0.211
Chapter XII Diseases of the skin and subcutaneous tissue	0.777	0.223
Chapter XX External causes of morbidity and mortality	0.772	0.228
S61.0 Open wound of finger(s) without damage to nail	0.769	0.231
Chapter V Mental and behavioural disorders	0.763	0.237
L80-L99 Other disorders of the skin and subcutaneous tissue	0.760	0.240
D10-D36 Benign neoplasms	0.739	0.261
C64-C68 Malignant neoplasms of urinary tract	0.737	0.263
S80-S89 Injuries to the knee and lower leg	0.732	0.268
L40-L45 Papulosquamous disorders	0.724	0.276
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.717	0.283
F40-F48 Neurotic, stress-related and somatoform disorders	0.716	0.284
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.716	0.284
C67 Malignant neoplasm of bladder	0.709	0.291
L82 Seborrhoeic keratosis	0.708	0.292
S70-S79 Injuries to the hip and thigh	0.705	0.295
S61.1 Open wound of finger(s) with damage to nail	0.697	0.303
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.696	0.303
D37-D48 Neoplasms of uncertain or unknown behaviour	0.694	0.306
C67.9 Bladder, unspecified	0.688	0.312
S50-S59 Injuries to the elbow and forearm	0.683	0.316
S40-S49 Injuries to the shoulder and upper arm	0.671	0.329
F41 Other anxiety disorders	0.670	0.330
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.664	0.336
L85 Other epidermal thickening	0.663	0.337
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.662	0.338
F41.2 Mixed anxiety and depressive disorder	0.661	0.339
T36-T50 Poisoning by drugs, medicaments and biological substances	0.659	0.341
Chapter VII Diseases of the eye and adnexa	0.657	0.343
C43-C44 Melanoma and other malignant neoplasms of skin	0.657	0.343
D24 Benign neoplasm of breast	0.657	0.343
Y83.6 Removal of other organ (partial) (total)	0.654	0.346
L89 Decubitus ulcer	0.654	0.346
T66-T78 Other and unspecified effects of external causes	0.653	0.347
L40 Psoriasis	0.652	0.348
D00-D09 In situ neoplasms	0.652	0.348
L81 Other disorders of pigmentation	0.647	0.353
T92 Sequelae of injuries of upper limb	0.642	0.358
D23 Other benign neoplasms of skin	0.640	0.360
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.636	0.364
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.633	0.367
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.630	0.370
S64 Injury of nerves at wrist and hand level	0.630	0.370
S82 Fracture of lower leg, including ankle	0.627	0.372
S80 Superficial injury of lower leg	0.627	0.373
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.625	0.375
S20-S29 Injuries to the thorax	0.622	0.378
F99-F99 Unspecified mental disorder	0.618	0.382
L43 Lichen planus	0.617	0.383
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.616	0.384
S10-S19 Injuries to the neck	0.615	0.384
S90-S99 Injuries to the ankle and foot	0.614	0.386
T15-T19 Effects of foreign body entering through natural orifice	0.611	0.389
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.611	0.389
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.609	0.391
D22 Melanocytic naevi	0.609	0.391
L83 Acanthosis nigricans	0.608	0.392
F30-F39 Mood [affective] disorders	0.608	0.392
D10 Benign neoplasm of mouth and pharynx	0.603	0.397
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.603	0.397
V10-V19 Pedal cyclist injured in transport accident	0.600	0.399
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.599	0.401
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.597	0.403
X20-X29 Contact with venomous animals and plants	0.597	0.403
Chapter I Certain infectious and parasitic diseases	0.596	0.404
L40.9 Psoriasis, unspecified	0.595	0.405
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.594	0.406
X40-X49 Accidental poisoning by and exposure to noxious substances	0.594	0.406
S72 Fracture of femur	0.589	0.411
T79-T79 Certain early complications of trauma	0.589	0.411
T33-T35 Frostbite	0.589	0.411
T26-T28 Burns and corrosions confined to eye and internal organs	0.589	0.411
T20-T25 Burns and corrosions of external body surface, specified by site	0.589	0.411
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.589	0.411
T00-T07 Injuries involving multiple body regions	0.589	0.411
L92 Granulomatous disorders of skin and subcutaneous tissue	0.588	0.412
L91 Hypertrophic disorders of skin	0.585	0.415
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.585	0.415
Y60-Y69 Misadventures to patients during surgical and medical care	0.585	0.415
Chapter XXII Codes for special purposes	0.583	0.417
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.581	0.419
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.579	0.421
S69 Other and unspecified injuries of wrist and hand	0.577	0.423
S67 Crushing injury of wrist and hand	0.577	0.423
S65 Injury of blood vessels at wrist and hand level	0.577	0.423
S60 Superficial injury of wrist and hand	0.577	0.423
S68 Traumatic amputation of wrist and hand	0.576	0.424
V20-V29 Motorcycle rider injured in transport accident	0.576	0.424
Chapter XVI Certain conditions originating in the perinatal period	0.574	0.426
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.574	0.426
C40-C41 Malignant neoplasms of bone and articular cartilage	0.574	0.426
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.574	0.426
F43 Reaction to severe stress, and adjustment disorders	0.573	0.427
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.572	0.428
F00-F09 Organic, including symptomatic, mental disorders	0.570	0.430
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.569	0.431
W20-W49 Exposure to inanimate mechanical forces	0.567	0.433
S61.7 Multiple open wounds of wrist and hand	0.566	0.434
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.566	0.434
L81.4 Other melanin hyperpigmentation	0.566	0.434
C51-C58 Malignant neoplasms of female genital organs	0.565	0.435
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.565	0.435
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.564	0.436
C92 Myeloid leukaemia	0.563	0.437
D27 Benign neoplasm of ovary	0.563	0.437
S52 Fracture of forearm	0.562	0.437
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.562	0.438
S71 Open wound of hip and thigh	0.561	0.439
L85.9 Epidermal thickening, unspecified	0.560	0.439
D12.5 Sigmoid colon	0.559	0.441
L50-L54 Urticaria and erythema	0.558	0.442
L10-L14 Bullous disorders	0.557	0.443
D21 Other benign neoplasms of connective and other soft tissue	0.557	0.443
C44 Other malignant neoplasms of skin	0.556	0.444
D23.3 Skin of other and unspecified parts of face	0.556	0.444
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.553	0.446
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.553	0.447
Y35-Y36 Legal intervention and operations of war	0.553	0.447
Y10-Y34 Event of undetermined intent	0.553	0.447
Y00-Y09 Assault	0.553	0.447
X85-X99 Assault	0.553	0.447
X60-X84 Intentional self-harm	0.553	0.447
X58-X59 Accidental exposure to other and unspecified factors	0.553	0.447
X50-X57 Overexertion, travel and privation	0.553	0.447
X30-X39 Exposure to forces of nature	0.553	0.447
X10-X19 Contact with heat and hot substances	0.553	0.447
X00-X09 Exposure to smoke, fire and flames	0.553	0.447
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.553	0.447
W75-W84 Other accidental threats to breathing	0.553	0.447
W65-W74 Accidental drowning and submersion	0.553	0.447
W50-W64 Exposure to animate mechanical forces	0.553	0.447
V98-V99 Other and unspecified transport accidents	0.553	0.447
V95-V97 Air and space transport accidents	0.553	0.447
V90-V94 Water transport accidents	0.553	0.447
V80-V89 Other land transport accidents	0.553	0.447
V70-V79 Bus occupant injured in transport accident	0.553	0.447
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.553	0.447
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.553	0.447
V40-V49 Car occupant injured in transport accident	0.553	0.447
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.553	0.447
V01-V09 Pedestrian injured in transport accident	0.553	0.447
Chapter XI Diseases of the digestive system	0.553	0.447
S61.8 Open wound of other parts of wrist and hand	0.552	0.448
L89.1 Stage II decubitus ulcer	0.552	0.448
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.547	0.453
F80-F89 Disorders of psychological development	0.547	0.453
F70-F79 Mental retardation	0.547	0.453
F60-F69 Disorders of adult personality and behaviour	0.547	0.453
T92.1 Sequelae of fracture of arm	0.546	0.454
S66 Injury of muscle and tendon at wrist and hand level	0.545	0.455
H53-H54 Visual disturbances and blindness	0.545	0.455
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.545	0.455
L95 Vasculitis limited to skin, not elsewhere classified	0.545	0.455
L94 Other localised connective tissue disorders	0.545	0.455
L93 Lupus erythematosus	0.545	0.455
L87 Transepidermal elimination disorders	0.545	0.455
L88 Pyoderma gangrenosum	0.545	0.455
L86 Keratoderma in diseases classified elsewhere	0.545	0.455
L80 Vitiligo	0.545	0.455
S62 Fracture at wrist and hand level	0.543	0.457
D11 Benign neoplasm of major salivary glands	0.542	0.458
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.542	0.458
L43.9 Lichen planus, unspecified	0.541	0.459
Y83.1 Surgical operation with implant of artificial internal device	0.540	0.460
H20 Iridocyclitis	0.539	0.461
T92.2 Sequelae of fracture at wrist and hand level	0.539	0.461
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.539	0.461
S00-S09 Injuries to the head	0.537	0.463
S42 Fracture of shoulder and upper arm	0.535	0.465
L85.8 Other specified epidermal thickening	0.535	0.465
D18 Haemangioma and lymphangioma, any site	0.534	0.466
T78 Adverse effects, not elsewhere classified	0.533	0.467
Chapter IX Diseases of the circulatory system	0.532	0.468
D33 Benign neoplasm of brain and other parts of central nervous system	0.530	0.470
D31 Benign neoplasm of eye and adnexa	0.530	0.470
D30 Benign neoplasm of urinary organs	0.530	0.470
D29 Benign neoplasm of male genital organs	0.530	0.470
D28 Benign neoplasm of other and unspecified female genital organs	0.530	0.470
D26 Other benign neoplasms of uterus	0.530	0.470
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.530	0.470
D19 Benign neoplasm of mesothelial tissue	0.530	0.470
D16 Benign neoplasm of bone and articular cartilage	0.530	0.470
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.530	0.470
D14 Benign neoplasm of middle ear and respiratory system	0.530	0.470
S40 Superficial injury of shoulder and upper arm	0.529	0.471
S82.5 Fracture of medial malleolus	0.529	0.471
H30-H36 Disorders of choroid and retina	0.529	0.471
C68 Malignant neoplasm of other and unspecified urinary organs	0.528	0.471
C66 Malignant neoplasm of ureter	0.528	0.471
C65 Malignant neoplasm of renal pelvis	0.528	0.471
Y57 Other and unspecified drugs and medicaments	0.528	0.472
C81 Hodgkin's disease	0.528	0.472
S50 Superficial injury of forearm	0.526	0.474
S61.9 Open wound of wrist and hand, part unspecified	0.525	0.475
S89 Other and unspecified injuries of lower leg	0.525	0.475
S88 Traumatic amputation of lower leg	0.525	0.475
S87 Crushing injury of lower leg	0.525	0.475
S86 Injury of muscle and tendon at lower leg level	0.525	0.475
S85 Injury of blood vessels at lower leg level	0.525	0.475
S84 Injury of nerves at lower leg level	0.525	0.475
S81 Open wound of lower leg	0.525	0.475
A00-A09 Intestinal infectious diseases	0.523	0.477
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.523	0.477
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.521	0.479
D04 Carcinoma in situ of skin	0.521	0.479
F45 Somatoform disorders	0.520	0.480
L44 Other papulosquamous disorders	0.519	0.481
L41 Parapsoriasis	0.519	0.481
L45 Papulosquamous disorders in diseases classified elsewhere	0.519	0.481
L42 Pityriasis rosea	0.519	0.481
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.517	0.483
S80.9 Superficial injury of lower leg, unspecified	0.517	0.483
T93 Sequelae of injuries of lower limb	0.515	0.485
L89.9 Decubitus ulcer and pressure area, unspecified	0.515	0.485
F99 Mental disorder, not otherwise specified	0.514	0.486
T98 Sequelae of other and unspecified effects of external causes	0.514	0.486
T95 Sequelae of burns, corrosions and frostbite	0.514	0.486
T94 Sequelae of injuries involving multiple and unspecified body regions	0.514	0.486
T91 Sequelae of injuries of neck and trunk	0.514	0.486
T90 Sequelae of injuries of head	0.514	0.486
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.514	0.486
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.514	0.486
D37.5 Rectum	0.514	0.486
F48 Other neurotic disorders	0.514	0.486
F44 Dissociative [conversion] disorders	0.514	0.486
F42 Obsessive-compulsive disorder	0.514	0.486
D35 Benign neoplasm of other and unspecified endocrine glands	0.513	0.487
F41.1 Generalised anxiety disorder	0.512	0.488
H55-H59 Other disorders of eye and adnexa	0.512	0.488
I30-I52 Other forms of heart disease	0.511	0.489
D23.6 Skin of upper limb, including shoulder	0.511	0.489
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.511	0.489
C85.1 B-cell lymphoma, unspecified	0.510	0.490
C67.2 Lateral wall of bladder	0.510	0.490
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.509	0.491
C15-C26 Malignant neoplasms of digestive organs	0.508	0.492
C67.8 Overlapping lesion of bladder	0.508	0.492
C67.7 Urachus	0.508	0.492
C67.6 Ureteric orifice	0.508	0.492
C67.5 Bladder neck	0.508	0.492
C67.4 Posterior wall of bladder	0.508	0.492
C67.3 Anterior wall of bladder	0.508	0.492
C67.1 Dome of bladder	0.508	0.492
C67.0 Trigone of bladder	0.508	0.492
D10.1 Tongue	0.506	0.494
F40 Phobic anxiety disorders	0.506	0.494
S64.4 Injury of digital nerve of other finger	0.505	0.494
S79 Other and unspecified injuries of hip and thigh	0.505	0.495
S78 Traumatic amputation of hip and thigh	0.505	0.495
S77 Crushing injury of hip and thigh	0.505	0.495
S76 Injury of muscle and tendon at hip and thigh level	0.505	0.495
S75 Injury of blood vessels at hip and thigh level	0.505	0.495
S74 Injury of nerves at hip and thigh level	0.505	0.495
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.505	0.495
S70 Superficial injury of hip and thigh	0.505	0.495
I34 Nonrheumatic mitral valve disorders	0.504	0.496
S80.8 Other superficial injuries of lower leg	0.504	0.496
H43-H45 Disorders of vitreous body and globe	0.504	0.496
Y83.9 Surgical procedure, unspecified	0.503	0.497
D06 Carcinoma in situ of cervix uteri	0.502	0.497
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.502	0.498
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.502	0.498
D32 Benign neoplasm of meninges	0.500	0.500
D17 Benign lipomatous neoplasm	0.500	0.500
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.499	0.500
C95 Leukaemia of unspecified cell type	0.499	0.500
C94 Other leukaemias of specified cell type	0.499	0.500
C93 Monocytic leukaemia	0.499	0.500
C88 Malignant immunoproliferative diseases	0.499	0.500
C86 Other specified types of T/NK-cell lymphoma	0.499	0.500
C84 Peripheral and cutaneous T-cell lymphomas	0.499	0.500
H20.9 Iridocyclitis, unspecified	0.498	0.502
T31 Burns classified according to extent of body surface involved	0.498	0.502
D46 Myelodysplastic syndromes	0.497	0.502
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.497	0.502
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.497	0.502
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.497	0.502
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.497	0.502
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.497	0.502
D23.5 Skin of trunk	0.497	0.502
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.496	0.504
S63.6 Sprain and strain of finger(s)	0.496	0.504
D34 Benign neoplasm of thyroid gland	0.496	0.504
S52.0 Fracture of upper end of ulna	0.495	0.505
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.495	0.505
K83 Other diseases of biliary tract	0.494	0.506
Chapter XXI Factors influencing health status and contact with health services	0.494	0.506
D22.3 Melanocytic naevi of other and unspecified parts of face	0.493	0.507
L84 Corns and callosities	0.493	0.507
T63 Toxic effect of contact with venomous animals	0.491	0.509
C44.1 Skin of eyelid, including canthus	0.490	0.510
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.490	0.510
S59 Other and unspecified injuries of forearm	0.490	0.510
S58 Traumatic amputation of forearm	0.490	0.510
S57 Crushing injury of forearm	0.490	0.510
S56 Injury of muscle and tendon at forearm level	0.490	0.510
S55 Injury of blood vessels at forearm level	0.490	0.510
S54 Injury of nerves at forearm level	0.490	0.510
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.490	0.510
S51 Open wound of forearm	0.490	0.510
D23.1 Skin of eyelid, including canthus	0.490	0.510
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.488	0.511
F33 Recurrent depressive disorder	0.488	0.512
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.487	0.513
L40.5 Arthropathic psoriasis	0.486	0.513
I34.0 Mitral (valve) insufficiency	0.485	0.514
Y40 Systemic antibiotics	0.485	0.515
D09 Carcinoma in situ of other and unspecified sites	0.484	0.516
C90 Multiple myeloma and malignant plasma cell neoplasms	0.484	0.516
Q20-Q28 Congenital malformations of the circulatory system	0.483	0.517
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.482	0.518
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.481	0.518
D22.7 Melanocytic naevi of lower limb, including hip	0.481	0.519
S49 Other and unspecified injuries of shoulder and upper arm	0.481	0.519
S48 Traumatic amputation of shoulder and upper arm	0.481	0.519
S46 Injury of muscle and tendon at shoulder and upper arm level	0.481	0.519
S45 Injury of blood vessels at shoulder and upper arm level	0.481	0.519
S44 Injury of nerves at shoulder and upper arm level	0.481	0.519
S41 Open wound of shoulder and upper arm	0.481	0.519
S47 Crushing injury of shoulder and upper arm	0.481	0.519
F41.8 Other specified anxiety disorders	0.480	0.520
F41.3 Other mixed anxiety disorders	0.480	0.520
C50-C50 Malignant neoplasm of breast	0.480	0.520
S82.4 Fracture of fibula alone	0.480	0.520
S82.1 Fracture of upper end of tibia	0.478	0.522
V18 Pedal cyclist injured in noncollision transport accident	0.478	0.522
H40-H42 Glaucoma	0.477	0.523
Y59 Other and unspecified vaccines and biological substances	0.476	0.524
Y58 Bacterial vaccines	0.476	0.524
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.476	0.524
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.476	0.524
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.476	0.524
Y53 Agents primarily affecting the gastro-intestinal system	0.476	0.524
Y52 Agents primarily affecting the cardiovascular system	0.476	0.524
Y50 Central nervous system stimulants, not elsewhere classified	0.476	0.524
Y49 Psychotropic drugs, not elsewhere classified	0.476	0.524
Y48 Anaesthetics and therapeutic gases	0.476	0.524
Y47 Sedatives, hypnotics and antianxiety drugs	0.476	0.524
Y46 Antiepileptics and anti-Parkinsonism drugs	0.476	0.524
Y44 Agents primarily affecting blood constituents	0.476	0.524
Y41 Other systemic anti-infectives and antiparasitics	0.476	0.524
C45 Mesothelioma	0.475	0.525
L85.3 Xerosis cutis	0.475	0.525
L85.2 Keratosis punctata (palmaris et plantaris)	0.475	0.525
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.475	0.525
L85.0 Acquired ichthyosis	0.475	0.525
Y83.5 Amputation of limb(s)	0.475	0.525
Y83.3 Surgical operation with formation of external stoma	0.475	0.525
Y83.0 Surgical operation with transplant of whole organ	0.475	0.525
Y84.8 Other medical procedures	0.475	0.525
H54 Blindness and low vision	0.474	0.526
S72.0 Fracture of neck of femur	0.474	0.526
A08 Viral and other specified intestinal infections	0.473	0.527
C73 Malignant neoplasm of thyroid gland	0.472	0.528
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.472	0.528
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.472	0.528
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.472	0.528
T46 Poisoning by agents primarily affecting the cardiovascular system	0.472	0.528
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.472	0.528
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.472	0.528
T41 Poisoning by anaesthetics and therapeutic gases	0.472	0.528
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.472	0.528
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.472	0.528
T36 Poisoning by systemic antibiotics	0.472	0.528
D36 Benign neoplasm of other and unspecified sites	0.472	0.528
C60-C63 Malignant neoplasms of male genital organs	0.472	0.528
H46-H48 Disorders of optic nerve and visual pathways	0.471	0.529
X23 Contact with hornets, wasps and bees	0.471	0.529
D37.7 Other digestive organs	0.471	0.529
C80 Malignant neoplasm without specification of site	0.471	0.529
H21 Other disorders of iris and ciliary body	0.471	0.529
S82.6 Fracture of lateral malleolus	0.469	0.531
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.469	0.531
H10-H13 Disorders of conjunctiva	0.469	0.531
L89.3 Stage IV decubitus ulcer	0.469	0.531
L89.2 Stage III decubitus ulcer	0.469	0.531
L89.0 Stage I decubitus ulcer and pressure area	0.469	0.531
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.468	0.531
T75 Effects of other external causes	0.468	0.531
T74 Maltreatment syndromes	0.468	0.531
T73 Effects of other deprivation	0.468	0.531
T70 Effects of air pressure and water pressure	0.468	0.531
T69 Other effects of reduced temperature	0.468	0.531
T67 Effects of heat and light	0.468	0.531
T71 Asphyxiation	0.468	0.531
T68 Hypothermia	0.468	0.531
T66 Unspecified effects of radiation	0.468	0.531
S27 Injury of other and unspecified intrathoracic organs	0.468	0.532
S12 Fracture of neck	0.468	0.532
C43 Malignant melanoma of skin	0.468	0.532
C92.0 Acute myeloid leukaemia	0.468	0.532
L40.8 Other psoriasis	0.468	0.532
L40.4 Guttate psoriasis	0.468	0.532
L40.3 Pustulosis palmaris et plantaris	0.468	0.532
L40.2 Acrodermatitis continua	0.468	0.532
L40.1 Generalised pustular psoriasis	0.468	0.532
L40.0 Psoriasis vulgaris	0.468	0.532
D07 Carcinoma in situ of other and unspecified genital organs	0.467	0.532
D03 Melanoma in situ	0.467	0.532
D02 Carcinoma in situ of middle ear and respiratory system	0.467	0.532
D01 Carcinoma in situ of other and unspecified digestive organs	0.467	0.532
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.467	0.532
A30-A49 Other bacterial diseases	0.467	0.533
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.467	0.533
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.467	0.533
S92 Fracture of foot, except ankle	0.466	0.534
Y51 Drugs primarily affecting the autonomic nervous system	0.465	0.535
K86 Other diseases of pancreas	0.465	0.535
D22.5 Melanocytic naevi of trunk	0.464	0.536
C78.4 Secondary malignant neoplasm of small intestine	0.464	0.536
L81.9 Disorder of pigmentation, unspecified	0.464	0.536
L81.8 Other specified disorders of pigmentation	0.464	0.536
L81.7 Pigmented purpuric dermatosis	0.464	0.536
L81.6 Other disorders of diminished melanin formation	0.464	0.536
L81.5 Leukoderma, not elsewhere classified	0.464	0.536
L81.3 Cafe au lait spots	0.464	0.536
L81.2 Freckles	0.464	0.536
L81.1 Chloasma	0.464	0.536
L81.0 Postinflammatory hyperpigmentation	0.464	0.536
F31 Bipolar affective disorder	0.463	0.537
C44.3 Skin of other and unspecified parts of face	0.463	0.537
L60-L75 Disorders of skin appendages	0.462	0.538
T17 Foreign body in respiratory tract	0.461	0.539
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.461	0.539
T92.9 Sequelae of unspecified injury of upper limb	0.460	0.540
T92.8 Sequelae of other specified injuries of upper limb	0.460	0.540
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.460	0.540
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.460	0.540
T92.4 Sequelae of injury of nerve of upper limb	0.460	0.540
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.460	0.540
T92.0 Sequelae of open wound of upper limb	0.460	0.540
I34.1 Mitral (valve) prolapse	0.460	0.540
S22 Fracture of rib(s), sternum and thoracic spine	0.460	0.540
L20-L30 Dermatitis and eczema	0.459	0.540
C44.5 Skin of trunk	0.460	0.540
D23.9 Skin, unspecified	0.459	0.541
D23.2 Skin of ear and external auricular canal	0.459	0.541
D23.0 Skin of lip	0.459	0.541
H35 Other retinal disorders	0.459	0.541
S82.50 Fracture of medial malleolus (closed)	0.459	0.541
S71.1 Open wound of thigh	0.458	0.541
Y45.1 Salicylates	0.458	0.542
L91.8 Other hypertrophic disorders of skin	0.458	0.542
F43.0 Acute stress reaction	0.457	0.543
C76 Malignant neoplasm of other and ill-defined sites	0.456	0.544
B35-B49 Mycoses	0.456	0.544
T51 Toxic effect of alcohol	0.455	0.545
C83 Diffuse non-Hodgkin's lymphoma	0.455	0.545
K83.8 Other specified diseases of biliary tract	0.455	0.545
W00-W19 Falls	0.455	0.545
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.454	0.546
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.454	0.546
T32 Corrosions classified according to extent of body surface involved	0.454	0.546
T30 Burn and corrosion, body region unspecified	0.454	0.546
T29 Burns and corrosions of multiple body regions	0.454	0.546
T65 Toxic effect of other and unspecified substances	0.452	0.548
T62 Toxic effect of other noxious substances eaten as food	0.452	0.548
T61 Toxic effect of noxious substances eaten as seafood	0.452	0.548
T60 Toxic effect of pesticides	0.452	0.548
T59 Toxic effect of other gases, fumes and vapours	0.452	0.548
T57 Toxic effect of other inorganic substances	0.452	0.548
T56 Toxic effect of metals	0.452	0.548
T54 Toxic effect of corrosive substances	0.452	0.548
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.452	0.548
T52 Toxic effect of organic solvents	0.452	0.548
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.452	0.548
T58 Toxic effect of carbon monoxide	0.452	0.548
T55 Toxic effect of soaps and detergents	0.452	0.548
S64.9 Injury of unspecified nerve at wrist and hand level	0.452	0.548
S64.8 Injury of other nerves at wrist and hand level	0.452	0.548
S64.7 Injury of multiple nerves at wrist and hand level	0.452	0.548
S64.3 Injury of digital nerve of thumb	0.452	0.548
S64.2 Injury of radial nerve at wrist and hand level	0.452	0.548
S64.1 Injury of median nerve at wrist and hand level	0.452	0.548
S64.0 Injury of ulnar nerve at wrist and hand level	0.452	0.548
Chapter VIII Diseases of the ear and mastoid process	0.451	0.549
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.451	0.549
D05 Carcinoma in situ of breast	0.450	0.550
Y43 Primarily systemic agents	0.450	0.550
S82.9 Fracture of lower leg, part unspecified	0.450	0.550
S82.7 Multiple fractures of lower leg	0.450	0.550
S82.0 Fracture of patella	0.450	0.550
D22.4 Melanocytic naevi of scalp and neck	0.450	0.550
F20 Schizophrenia	0.450	0.550
S72.3 Fracture of shaft of femur	0.449	0.550
S80.7 Multiple superficial injuries of lower leg	0.449	0.551
S80.1 Contusion of other and unspecified parts of lower leg	0.449	0.551
S80.0 Contusion of knee	0.449	0.551
D12.2 Ascending colon	0.449	0.551
S63.1 Dislocation finger	0.448	0.552
S63.7 Sprain and strain of other and unspecified parts of hand	0.448	0.552
S63.5 Sprain and strain of wrist	0.448	0.552
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.448	0.552
S63.3 Traumatic rupture of ligament of wrist and carpus	0.448	0.552
S63.2 Multiple dislocations of fingers	0.448	0.552
S63.0 Dislocation of wrist	0.448	0.552

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations