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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10518960
log Bayes Factor = 17.1635
Chromosome 15   position 45,334,829  (GRCh37) Explore rs10518960 on Ensembl!
Variant rs10518960 is part of Cluster X0276

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
E10.9 Without complications
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.992 0.008 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.990 0.010 0.000
C79 Secondary malignant neoplasm of other sites
0.986 0.014 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
Chapter IX Diseases of the circulatory system
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.981 0.019 0.000
H30-H36 Disorders of choroid and retina
0.980 0.020 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.975 0.025 0.000
E11 Non-insulin-dependent diabetes mellitus
0.974 0.026 0.000
E14 Unspecified diabetes mellitus
0.973 0.027 0.000
C78.7 Secondary malignant neoplasm of liver
0.972 0.028 0.000
F10.1 Harmful use
0.971 0.029 0.000
C60-C63 Malignant neoplasms of male genital organs
0.971 0.029 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.965 0.035 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.961 0.039 0.000
F10.2 Dependence syndrome
0.956 0.044 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.955 0.045 0.000
E14.9 Without complications
0.952 0.048 0.000
D50-D53 Nutritional anaemias
0.951 0.049 0.000
C78.0 Secondary malignant neoplasm of lung
0.948 0.052 0.000
I26 Pulmonary embolism
0.948 0.052 0.000
I60-I69 Cerebrovascular diseases
0.945 0.055 0.000
C61 Malignant neoplasm of prostate
0.945 0.055 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.944 0.056 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.943 0.057 0.000
H35 Other retinal disorders
0.942 0.058 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.929 0.071 0.000
E11.3 With ophthalmic complications
0.922 0.078 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.922 0.078 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.922 0.078 0.000
I63 Cerebral infarction
0.922 0.078 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.920 0.080 0.000
Chapter X Diseases of the respiratory system
0.917 0.083 0.000
E11.9 Without complications
0.904 0.096 0.000
H25-H28 Disorders of lens
0.904 0.096 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.900 0.100 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.898 0.102 0.000
D50 Iron deficiency anaemia
0.897 0.103 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.896 0.104 0.000
C77.4 Inguinal and lower limb lymph nodes
0.890 0.110 0.000
E70-E90 Metabolic disorders
0.890 0.110 0.000
C78.2 Secondary malignant neoplasm of pleura
0.890 0.110 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.889 0.111 0.000
E10.3 With ophthalmic complications
0.888 0.112 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.885 0.115 0.000
I63.9 Cerebral infarction, unspecified
0.883 0.117 0.000
H36 Retinal disorders in diseases classified elsewhere
0.881 0.119 0.000
E20-E35 Disorders of other endocrine glands
0.880 0.120 0.000
I05-I09 Chronic rheumatic heart diseases
0.877 0.123 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.872 0.128 0.000
D51 Vitamin B12 deficiency anaemia
0.872 0.128 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.872 0.128 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.871 0.129 0.000
J95-J99 Other diseases of the respiratory system
0.870 0.130 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.870 0.130 0.000
W50-W64 Exposure to animate mechanical forces
0.866 0.134 0.000
H18 Other disorders of cornea
0.866 0.134 0.000
Chapter I Certain infectious and parasitic diseases
0.857 0.143 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.851 0.149 0.000
H25 Senile cataract
0.851 0.149 0.000
C77.2 Intra-abdominal lymph nodes
0.850 0.150 0.000
W00-W19 Falls
0.847 0.153 0.000
X60-X84 Intentional self-harm
0.846 0.154 0.000
H25.1 Senile nuclear cataract
0.840 0.160 0.000
J98 Other respiratory disorders
0.839 0.161 0.000
T92 Sequelae of injuries of upper limb
0.838 0.162 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.836 0.164 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.835 0.165 0.000
D45 Polycythaemia vera
0.834 0.166 0.000
F30-F39 Mood [affective] disorders
0.831 0.169 0.000
M80-M85 Disorders of bone density and structure
0.831 0.169 0.000
F10.3 Withdrawal state
0.829 0.171 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.829 0.171 0.000
I69 Sequelae of cerebrovascular disease
0.825 0.175 0.000
H21 Other disorders of iris and ciliary body
0.817 0.183 0.000
D50.9 Iron deficiency anaemia, unspecified
0.816 0.184 0.000
C51-C58 Malignant neoplasms of female genital organs
0.816 0.184 0.000
M20-M25 Other joint disorders
0.814 0.186 0.000
C79.2 Secondary malignant neoplasm of skin
0.812 0.188 0.000
H36.0 Diabetic retinopathy
0.810 0.190 0.000
T39.0 Salicylates
0.808 0.192 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.806 0.194 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.804 0.196 0.000
H55-H59 Other disorders of eye and adnexa
0.804 0.196 0.000
D50.8 Other iron deficiency anaemias
0.803 0.197 0.000
F60-F69 Disorders of adult personality and behaviour
0.803 0.197 0.000
H53-H54 Visual disturbances and blindness
0.801 0.199 0.000
T39.1 4-Aminophenol derivatives
0.801 0.199 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.799 0.201 0.000
H35.9 Retinal disorder, unspecified
0.795 0.205 0.000
C64-C68 Malignant neoplasms of urinary tract
0.794 0.206 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.788 0.212 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.788 0.212 0.000
H34 Retinal vascular occlusions
0.784 0.216 0.000
D75 Other diseases of blood and blood-forming organs
0.783 0.217 0.000
T40.2 Other opioids
0.781 0.219 0.000
W55 Bitten or struck by other mammals
0.781 0.219 0.000
T91 Sequelae of injuries of neck and trunk
0.780 0.220 0.000
S70-S79 Injuries to the hip and thigh
0.780 0.220 0.000
L20-L30 Dermatitis and eczema
0.779 0.221 0.000
E10.1 With ketoacidosis
0.779 0.221 0.000
H35.0 Background retinopathy and retinal vascular changes
0.778 0.222 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.776 0.224 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.774 0.226 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.774 0.226 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.772 0.228 0.000
M65-M68 Disorders of synovium and tendon
0.771 0.229 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.770 0.230 0.000
V40-V49 Car occupant injured in transport accident
0.770 0.230 0.000
Q60-Q64 Congenital malformations of the urinary system
0.769 0.231 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.769 0.231 0.000
Y86 Sequelae of other accidents
0.769 0.231 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.768 0.232 0.000
S50-S59 Injuries to the elbow and forearm
0.767 0.233 0.000
H35.4 Peripheral retinal degeneration
0.766 0.234 0.000
H31 Other disorders of choroid
0.765 0.235 0.000
H50 Other strabismus
0.764 0.236 0.000
C77.8 Lymph nodes of multiple regions
0.763 0.237 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.762 0.238 0.000
I08 Multiple valve diseases
0.761 0.239 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.759 0.241 0.000
H52 Disorders of refraction and accommodation
0.758 0.242 0.000
Y85 Sequelae of transport accidents
0.757 0.243 0.000
S90-S99 Injuries to the ankle and foot
0.757 0.243 0.000
H35.5 Hereditary retinal dystrophy
0.756 0.244 0.000
H18.8 Other specified disorders of cornea
0.756 0.244 0.000
H43-H45 Disorders of vitreous body and globe
0.756 0.244 0.000
S00-S09 Injuries to the head
0.755 0.245 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.755 0.245 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.755 0.245 0.000
E87.6 Hypokalaemia
0.753 0.247 0.000
C09 Malignant neoplasm of tonsil
0.752 0.248 0.000
H27 Other disorders of lens
0.751 0.249 0.000
Chapter XI Diseases of the digestive system
0.751 0.249 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.750 0.250 0.000
V80-V89 Other land transport accidents
0.750 0.250 0.000
D80-D89 Certain disorders involving the immune mechanism
0.750 0.250 0.000
C77.0 Lymph nodes of head, face and neck
0.749 0.251 0.000
T90 Sequelae of injuries of head
0.749 0.251 0.000
C62 Malignant neoplasm of testis
0.748 0.252 0.000
L40-L45 Papulosquamous disorders
0.748 0.252 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.748 0.252 0.000
I27 Other pulmonary heart diseases
0.747 0.253 0.000
Y52 Agents primarily affecting the cardiovascular system
0.747 0.253 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.746 0.254 0.000
S10-S19 Injuries to the neck
0.745 0.254 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.745 0.255 0.000
E40-E46 Malnutrition
0.744 0.256 0.000
H54 Blindness and low vision
0.743 0.257 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.742 0.258 0.000
K70-K77 Diseases of liver
0.738 0.262 0.000
T93 Sequelae of injuries of lower limb
0.737 0.263 0.000
T79-T79 Certain early complications of trauma
0.736 0.264 0.000
C79.6 Secondary malignant neoplasm of ovary
0.735 0.265 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.266 0.000
F01 Vascular dementia
0.733 0.266 0.000
V20-V29 Motorcycle rider injured in transport accident
0.733 0.267 0.000
B15-B19 Viral hepatitis
0.732 0.268 0.000
M22 Disorders of patella
0.731 0.269 0.000
I69.3 Sequelae of cerebral infarction
0.728 0.272 0.000
T66-T78 Other and unspecified effects of external causes
0.728 0.272 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.727 0.272 0.000
E65-E68 Obesity and other hyperalimentation
0.727 0.273 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.727 0.273 0.000
E22 Hyperfunction of pituitary gland
0.726 0.274 0.000
H18.5 Hereditary corneal dystrophies
0.726 0.274 0.000
D75.1 Secondary polycythaemia
0.725 0.275 0.000
E50-E64 Other nutritional deficiencies
0.725 0.275 0.000
F03 Unspecified dementia
0.725 0.275 0.000
H35.8 Other specified retinal disorders
0.724 0.276 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.724 0.276 0.000
E13 Other specified diabetes mellitus
0.724 0.276 0.000
E27 Other disorders of adrenal gland
0.723 0.276 0.000
H10-H13 Disorders of conjunctiva
0.723 0.277 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.721 0.279 0.000
T51 Toxic effect of alcohol
0.721 0.279 0.000
W55.0 Home
0.720 0.280 0.000
M45-M49 Spondylopathies
0.720 0.280 0.000
M34 Systemic sclerosis
0.718 0.282 0.000
E00-E07 Disorders of thyroid gland
0.718 0.282 0.000
D48.5 Skin
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
E10.8 With unspecified complications
0.716 0.283 0.000
E10.7 With multiple complications
0.716 0.283 0.000
E10.6 With other specified complications
0.716 0.283 0.000
E10.5 With peripheral circulatory complications
0.716 0.283 0.000
E10.2 With renal complications
0.716 0.283 0.000
E10.0 With coma
0.716 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
D00-D09 In situ neoplasms
0.715 0.285 0.000
H17 Corneal scars and opacities
0.715 0.285 0.000
E14.3 With ophthalmic complications
0.714 0.286 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.713 0.287 0.000
J60-J70 Lung diseases due to external agents
0.712 0.288 0.000
J98.9 Respiratory disorder, unspecified
0.712 0.288 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.711 0.288 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.711 0.288 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.711 0.288 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.711 0.288 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.711 0.288 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.711 0.288 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.711 0.288 0.000
F11 Mental and behavioural disorders due to use of opioids
0.711 0.288 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.711 0.289 0.000
C80 Malignant neoplasm without specification of site
0.710 0.290 0.000
F10.9 Unspecified mental and behavioural disorder
0.709 0.290 0.000
F10.8 Other mental and behavioural disorders
0.709 0.290 0.000
F10.7 Residual and late-onset psychotic disorder
0.709 0.290 0.000
F10.6 Amnesic syndrome
0.709 0.290 0.000
F10.5 Psychotic disorder
0.709 0.290 0.000
F10.4 Withdrawal state with delirium
0.709 0.290 0.000
C77.9 Lymph node, unspecified
0.709 0.291 0.000
D70 Agranulocytosis
0.709 0.291 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.709 0.291 0.000
Q50-Q56 Congenital malformations of genital organs
0.709 0.291 0.000
H35.6 Retinal haemorrhage
0.708 0.292 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.708 0.292 0.000
E10.4 With neurological complications
0.708 0.292 0.000
J98.1 Pulmonary collapse
0.707 0.293 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.707 0.293 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.707 0.293 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
Y00-Y09 Assault
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.706 0.294 0.000
X50-X57 Overexertion, travel and privation
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
X10-X19 Contact with heat and hot substances
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
I00-I02 Acute rheumatic fever
0.705 0.295 0.000
I05 Rheumatic mitral valve diseases
0.704 0.296 0.000
C10 Malignant neoplasm of oropharynx
0.704 0.296 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.296 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.296 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.703 0.296 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.703 0.296 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.296 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.296 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.296 0.000
T36 Poisoning by systemic antibiotics
0.703 0.296 0.000
E11.5 With peripheral circulatory complications
0.703 0.297 0.000
Chapter XXII Codes for special purposes
0.703 0.297 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.703 0.297 0.000
H30 Chorioretinal inflammation
0.703 0.297 0.000
K35-K38 Diseases of appendix
0.700 0.300 0.000
I62 Other nontraumatic intracranial haemorrhage
0.700 0.300 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.700 0.300 0.000
D55-D59 Haemolytic anaemias
0.699 0.301 0.000
E11.8 With unspecified complications
0.698 0.302 0.000
E11.7 With multiple complications
0.698 0.302 0.000
E11.6 With other specified complications
0.698 0.302 0.000
E11.1 With ketoacidosis
0.698 0.302 0.000
E11.0 With coma
0.698 0.302 0.000
E14.8 With unspecified complications
0.697 0.303 0.000
E14.7 With multiple complications
0.697 0.303 0.000
E14.6 With other specified complications
0.697 0.303 0.000
E14.5 With peripheral circulatory complications
0.697 0.303 0.000
E14.4 With neurological complications
0.697 0.303 0.000
E14.2 Withrenal complications
0.697 0.303 0.000
E14.1 With ketoacidosis
0.697 0.303 0.000
E14.0 With coma
0.697 0.303 0.000
M80 Osteoporosis with pathological fracture
0.697 0.303 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.697 0.303 0.000
S20-S29 Injuries to the thorax
0.697 0.303 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.697 0.303 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.697 0.303 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.696 0.304 0.000
C60 Malignant neoplasm of penis
0.696 0.304 0.000
M91-M94 Chondropathies
0.696 0.304 0.000
A30-A49 Other bacterial diseases
0.696 0.304 0.000
K76 Other diseases of liver
0.696 0.304 0.000
H35.3 Degeneration of macula and posterior pole
0.695 0.305 0.000
F00 Dementia in Alzheimer's disease
0.695 0.305 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.693 0.307 0.000
J98.4 Other disorders of lung
0.693 0.307 0.000
J40-J47 Chronic lower respiratory diseases
0.692 0.308 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.692 0.308 0.000
I28 Other diseases of pulmonary vessels
0.692 0.308 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.691 0.309 0.000
C77.3 Axillary and upper limb lymph nodes
0.690 0.310 0.000
S40-S49 Injuries to the shoulder and upper arm
0.689 0.311 0.000
I30-I52 Other forms of heart disease
0.689 0.311 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.689 0.311 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.689 0.311 0.000
E34 Other endocrine disorders
0.688 0.312 0.000
J90-J94 Other diseases of pleura
0.688 0.312 0.000
I63.8 Other cerebral infarction
0.687 0.313 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.687 0.313 0.000
F33 Recurrent depressive disorder
0.687 0.313 0.000
E11.2 With renal complications
0.686 0.314 0.000
Chapter VIII Diseases of the ear and mastoid process
0.686 0.314 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.685 0.315 0.000
M85 Other disorders of bone density and structure
0.685 0.315 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.685 0.315 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.685 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.317 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.683 0.317 0.000
C77.5 Intrapelvic lymph nodes
0.682 0.318 0.000
D53 Other nutritional anaemias
0.682 0.318 0.000
C51 Malignant neoplasm of vulva
0.679 0.321 0.000
T92.1 Sequelae of fracture of arm
0.678 0.322 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.678 0.322 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.678 0.322 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.677 0.323 0.000
T98 Sequelae of other and unspecified effects of external causes
0.677 0.323 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.323 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.677 0.323 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.676 0.324 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.676 0.324 0.000
H15 Disorders of sclera
0.676 0.324 0.000
W07 Fall involving chair
0.676 0.324 0.000
K70 Alcoholic liver disease
0.676 0.324 0.000
H35.7 Separation of retinal layers
0.675 0.325 0.000
H35.2 Other proliferative retinopathy
0.675 0.325 0.000
H35.1 Retinopathy of prematurity
0.675 0.325 0.000
X62.9 Unspecified place
0.674 0.326 0.000
E24 Cushing's syndrome
0.674 0.326 0.000
Q61 Cystic kidney disease
0.674 0.326 0.000
F80-F89 Disorders of psychological development
0.673 0.327 0.000
H54.0 Blindness, both eyes
0.673 0.327 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.672 0.328 0.000
C01 Malignant neoplasm of base of tongue
0.671 0.329 0.000
W13 Fall from, out of or through building or structure
0.671 0.329 0.000
F32 Depressive episode
0.669 0.331 0.000
H50.0 Convergent concomitant strabismus
0.669 0.331 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.669 0.331 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.668 0.332 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.668 0.332 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.666 0.334 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.666 0.334 0.000
K65-K67 Diseases of peritoneum
0.666 0.334 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.665 0.335 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.665 0.335 0.000
F60 Specific personality disorders
0.663 0.337 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.663 0.337 0.000
O60-O75 Complications of labour and delivery
0.662 0.338 0.000
H21.0 Hyphaema
0.661 0.339 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.661 0.339 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.661 0.339 0.000
T39.4 Antirheumatics, not elsewhere classified
0.661 0.339 0.000
T39.2 Pyrazolone derivatives
0.661 0.339 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.661 0.339 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.661 0.339 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.661 0.339 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.661 0.339 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.661 0.339 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.661 0.339 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.661 0.339 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.661 0.339 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.661 0.339 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.661 0.339 0.000
H16 Keratitis
0.660 0.340 0.000
H49 Paralytic strabismus
0.660 0.340 0.000
M60-M63 Disorders of muscles
0.659 0.341 0.000
J20-J22 Other acute lower respiratory infections
0.659 0.341 0.000
I08.0 Disorders of both mitral and aortic valves
0.659 0.341 0.000
Y85.0 Sequelae of motor-vehicle accident
0.658 0.342 0.000
M81 Osteoporosis without pathological fracture
0.658 0.342 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.658 0.342 0.000
C09.9 Tonsil, unspecified
0.657 0.343 0.000
M86-M90 Other osteopathies
0.657 0.343 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.656 0.344 0.000
Y40 Systemic antibiotics
0.656 0.344 0.000
B99-B99 Other infectious diseases
0.654 0.346 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.654 0.346 0.000
S50 Superficial injury of forearm
0.654 0.346 0.000
M00-M03 Infectious arthropathies
0.653 0.347 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.653 0.347 0.000
M40-M43 Deforming dorsopathies
0.653 0.347 0.000
M70-M79 Other soft tissue disorders
0.653 0.347 0.000
E87.2 Acidosis
0.652 0.348 0.000
M65 Synovitis and tenosynovitis
0.652 0.348 0.000
W17 Other fall from one level to another
0.651 0.349 0.000
M24 Other specific joint derangements
0.651 0.349 0.000
D52 Folate deficiency anaemia
0.651 0.349 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.651 0.349 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.649 0.351 0.000
E23 Hypofunction and other disorders of pituitary gland
0.649 0.351 0.000
T40.4 Other synthetic narcotics
0.649 0.351 0.000
W18 Other fall on same level
0.649 0.351 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.649 0.351 0.000
C15-C26 Malignant neoplasms of digestive organs
0.649 0.351 0.000
K35 Acute appendicitis
0.648 0.352 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.648 0.352 0.000
H18.4 Corneal degeneration
0.648 0.352 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.648 0.352 0.000
H51 Other disorders of binocular movement
0.645 0.355 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.645 0.355 0.000
D46 Myelodysplastic syndromes
0.645 0.355 0.000
L30 Other dermatitis
0.645 0.355 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.644 0.356 0.000
Q80-Q89 Other congenital malformations
0.644 0.356 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.644 0.356 0.000
Q35-Q37 Cleft lip and cleft palate
0.644 0.356 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.644 0.356 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.644 0.356 0.000
I65.2 Occlusion and stenosis of carotid artery
0.643 0.357 0.000
D50.1 Sideropenic dysphagia
0.643 0.357 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.642 0.357 0.000
F02 Dementia in other diseases classified elsewhere
0.642 0.357 0.000
F09 Unspecified organic or symptomatic mental disorder
0.642 0.357 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.642 0.357 0.000
I07 Rheumatic tricuspid valve diseases
0.642 0.358 0.000
H27.0 Aphakia
0.642 0.358 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.640 0.360 0.000
H52.3 Anisometropia and aniseikonia
0.640 0.360 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.639 0.361 0.000
E85 Amyloidosis
0.638 0.362 0.000
E84 Cystic fibrosis
0.638 0.362 0.000
E79 Disorders of purine and pyrimidine metabolism
0.638 0.362 0.000
E77 Disorders of glycoprotein metabolism
0.638 0.362 0.000
E76 Disorders of glycosaminoglycan metabolism
0.638 0.362 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.638 0.362 0.000
E74 Other disorders of carbohydrate metabolism
0.638 0.362 0.000
E73 Lactose intolerance
0.638 0.362 0.000
E72 Other disorders of amino-acid metabolism
0.638 0.362 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.638 0.362 0.000
E70 Disorders of aromatic amino-acid metabolism
0.638 0.362 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.638 0.362 0.000
Y89 Sequelae of other external causes
0.637 0.362 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.637 0.362 0.000
C66 Malignant neoplasm of ureter
0.637 0.363 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.635 0.365 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.635 0.365 0.000
C13 Malignant neoplasm of hypopharynx
0.635 0.365 0.000
C11 Malignant neoplasm of nasopharynx
0.635 0.365 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.635 0.365 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.635 0.365 0.000
C05 Malignant neoplasm of palate
0.635 0.365 0.000
C04 Malignant neoplasm of floor of mouth
0.635 0.365 0.000
C03 Malignant neoplasm of gum
0.635 0.365 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.635 0.365 0.000
C00 Malignant neoplasm of lip
0.635 0.365 0.000
C12 Malignant neoplasm of pyriform sinus
0.635 0.365 0.000
C07 Malignant neoplasm of parotid gland
0.635 0.365 0.000
F99-F99 Unspecified mental disorder
0.634 0.366 0.000
D48.7 Other specified sites
0.634 0.366 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.634 0.366 0.000
S70 Superficial injury of hip and thigh
0.632 0.367 0.000
I20-I25 Ischaemic heart diseases
0.632 0.368 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.632 0.368 0.000
L29 Pruritus
0.632 0.368 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.631 0.369 0.000
E32 Diseases of thymus
0.631 0.369 0.000
E31 Polyglandular dysfunction
0.631 0.369 0.000
E30 Disorders of puberty, not elsewhere classified
0.631 0.369 0.000
E29 Testicular dysfunction
0.631 0.369 0.000
E26 Hyperaldosteronism
0.631 0.369 0.000
E25 Adrenogenital disorders
0.631 0.369 0.000
E20 Hypoparathyroidism
0.631 0.369 0.000
M22.4 Chondromalacia patellae
0.631 0.369 0.000
H55 Nystagmus and other irregular eye movements
0.631 0.369 0.000
S71 Open wound of hip and thigh
0.631 0.369 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.630 0.370 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.630 0.370 0.000
E87.0 Hyperosmolality and hypernatraemia
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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