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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111361850
log Bayes Factor = 1.08712
Chromosome 4   position 124,663,356  (GRCh37) Explore rs111361850 on Ensembl!
Variant rs111361850 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.918 0.082 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.872 0.128 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.871 0.129 0.000
Chapter XI Diseases of the digestive system
0.846 0.154 0.000
Chapter VI Diseases of the nervous system
0.838 0.162 0.000
Chapter IX Diseases of the circulatory system
0.824 0.176 0.000
R50-R69 General symptoms and signs
0.796 0.204 0.000
Chapter XIV Diseases of the genitourinary system
0.770 0.230 0.000
Chapter II Neoplasms
0.765 0.235 0.000
K90-K93 Other diseases of the digestive system
0.760 0.240 0.000
Chapter X Diseases of the respiratory system
0.759 0.241 0.000
M15-M19 Arthrosis
0.757 0.243 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.750 0.250 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.738 0.262 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.730 0.270 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.729 0.271 0.000
Chapter XX External causes of morbidity and mortality
0.727 0.273 0.000
M70-M79 Other soft tissue disorders
0.725 0.275 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.716 0.284 0.000
Chapter V Mental and behavioural disorders
0.712 0.288 0.000
M20-M25 Other joint disorders
0.705 0.295 0.000
I20-I25 Ischaemic heart diseases
0.703 0.297 0.000
G40-G47 Episodic and paroxysmal disorders
0.702 0.298 0.000
K92 Other diseases of digestive system
0.699 0.301 0.000
R50 Fever of unknown origin
0.693 0.307 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.692 0.308 0.000
K55-K64 Other diseases of intestines
0.690 0.310 0.000
K50-K52 Noninfective enteritis and colitis
0.687 0.313 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.686 0.314 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.683 0.317 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.680 0.319 0.000
N20-N23 Urolithiasis
0.668 0.332 0.000
Chapter I Certain infectious and parasitic diseases
0.666 0.334 0.000
Chapter XXII Codes for special purposes
0.658 0.342 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.658 0.342 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.658 0.342 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.658 0.342 0.000
Chapter VIII Diseases of the ear and mastoid process
0.658 0.342 0.000
M05-M14 Inflammatory polyarthropathies
0.656 0.344 0.000
Chapter VII Diseases of the eye and adnexa
0.654 0.346 0.000
I60-I69 Cerebrovascular diseases
0.653 0.347 0.000
M50-M54 Other dorsopathies
0.645 0.354 0.000
R56 Convulsions, not elsewhere classified
0.645 0.355 0.000
M45-M49 Spondylopathies
0.643 0.357 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.643 0.357 0.000
R51 Headache
0.642 0.358 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.640 0.360 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.635 0.364 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.634 0.366 0.000
M17 Gonarthrosis [arthrosis of knee]
0.631 0.369 0.000
K92.1 Melaena
0.629 0.371 0.000
R10 Abdominal and pelvic pain
0.627 0.373 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.625 0.375 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.625 0.375 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.625 0.375 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.625 0.375 0.000
R47-R49 Symptoms and signs involving speech and voice
0.625 0.375 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.625 0.375 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.625 0.375 0.000
E10-E14 Diabetes mellitus
0.625 0.375 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.624 0.376 0.000
M91-M94 Chondropathies
0.624 0.376 0.000
M86-M90 Other osteopathies
0.624 0.376 0.000
M80-M85 Disorders of bone density and structure
0.624 0.376 0.000
M65-M68 Disorders of synovium and tendon
0.624 0.376 0.000
M60-M63 Disorders of muscles
0.624 0.376 0.000
M40-M43 Deforming dorsopathies
0.624 0.376 0.000
M00-M03 Infectious arthropathies
0.624 0.376 0.000
M75 Shoulder lesions
0.620 0.379 0.000
R50.9 Fever, unspecified
0.619 0.380 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.619 0.381 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.618 0.382 0.000
M16 Coxarthrosis [arthrosis of hip]
0.617 0.383 0.000
K62 Other diseases of anus and rectum
0.616 0.384 0.000
J20-J22 Other acute lower respiratory infections
0.613 0.387 0.000
M23 Internal derangement of knee
0.609 0.391 0.000
K70-K77 Diseases of liver
0.606 0.394 0.000
K65-K67 Diseases of peritoneum
0.606 0.394 0.000
K35-K38 Diseases of appendix
0.606 0.394 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.606 0.394 0.000
R30-R39 Symptoms and signs involving the urinary system
0.605 0.395 0.000
G90-G99 Other disorders of the nervous system
0.601 0.399 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.601 0.399 0.000
G70-G73 Diseases of myoneural junction and muscle
0.601 0.399 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.601 0.399 0.000
G30-G32 Other degenerative diseases of the nervous system
0.601 0.399 0.000
G20-G26 Extrapyramidal and movement disorders
0.601 0.399 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.601 0.399 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.601 0.399 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.597 0.403 0.000
R63 Symptoms and signs concerning food and fluid intake
0.592 0.408 0.000
I30-I52 Other forms of heart disease
0.591 0.409 0.000
I05-I09 Chronic rheumatic heart diseases
0.591 0.409 0.000
I00-I02 Acute rheumatic fever
0.591 0.409 0.000
J09-J18 Influenza and pneumonia
0.591 0.409 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.590 0.410 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.590 0.410 0.000
R15 Faecal incontinence
0.584 0.416 0.000
R69 Unknown and unspecified causes of morbidity
0.580 0.420 0.000
J95-J99 Other diseases of the respiratory system
0.573 0.427 0.000
I84 Haemorrhoids
0.572 0.427 0.000
J30-J39 Other diseases of upper respiratory tract
0.572 0.428 0.000
G35 Multiple sclerosis
0.572 0.428 0.000
R00 Abnormalities of heart beat
0.571 0.429 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.571 0.429 0.000
R68 Other general symptoms and signs
0.570 0.429 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.570 0.429 0.000
R62 Lack of expected normal physiological development
0.570 0.429 0.000
R61 Hyperhidrosis
0.570 0.429 0.000
R60 Oedema, not elsewhere classified
0.570 0.429 0.000
R59 Enlarged lymph nodes
0.570 0.429 0.000
R57 Shock, not elsewhere classified
0.570 0.429 0.000
R52 Pain, not elsewhere classified
0.570 0.429 0.000
R64 Cachexia
0.570 0.429 0.000
R58 Haemorrhage, not elsewhere classified
0.570 0.429 0.000
R54 Senility
0.570 0.429 0.000
R53 Malaise and fatigue
0.570 0.429 0.000
N20 Calculus of kidney and ureter
0.570 0.430 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.568 0.432 0.000
L20-L30 Dermatitis and eczema
0.567 0.433 0.000
E00-E07 Disorders of thyroid gland
0.567 0.433 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.566 0.434 0.000
D60-D64 Aplastic and other anaemias
0.565 0.435 0.000
I21 Acute myocardial infarction
0.565 0.435 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.562 0.437 0.000
E70-E90 Metabolic disorders
0.560 0.440 0.000
K62.5 Haemorrhage of anus and rectum
0.559 0.441 0.000
D50-D53 Nutritional anaemias
0.558 0.442 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.555 0.445 0.000
C79 Secondary malignant neoplasm of other sites
0.554 0.445 0.000
N30-N39 Other diseases of urinary system
0.554 0.446 0.000
D10-D36 Benign neoplasms
0.554 0.446 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.553 0.447 0.000
N99-N99 Other disorders of the genitourinary system
0.552 0.448 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.552 0.448 0.000
N60-N64 Disorders of breast
0.552 0.448 0.000
N25-N29 Other disorders of kidney and ureter
0.552 0.448 0.000
N17-N19 Renal failure
0.552 0.448 0.000
N10-N16 Renal tubulo-interstitial diseases
0.552 0.448 0.000
N00-N08 Glomerular diseases
0.552 0.448 0.000
K58 Irritable bowel syndrome
0.551 0.449 0.000
G40 Epilepsy
0.550 0.450 0.000
K92.0 Haematemesis
0.549 0.451 0.000
M17.9 Gonarthrosis, unspecified
0.549 0.451 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.549 0.451 0.000
D00-D09 In situ neoplasms
0.549 0.451 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.549 0.451 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.549 0.451 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.549 0.451 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.549 0.451 0.000
C64-C68 Malignant neoplasms of urinary tract
0.549 0.451 0.000
C51-C58 Malignant neoplasms of female genital organs
0.549 0.451 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.549 0.451 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.549 0.451 0.000
C15-C26 Malignant neoplasms of digestive organs
0.549 0.451 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.549 0.451 0.000
I25 Chronic ischaemic heart disease
0.547 0.453 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.545 0.455 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.545 0.455 0.000
K90 Intestinal malabsorption
0.545 0.455 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.544 0.456 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.544 0.456 0.000
J60-J70 Lung diseases due to external agents
0.544 0.456 0.000
J00-J06 Acute upper respiratory infections
0.544 0.456 0.000
I20 Angina pectoris
0.544 0.456 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.543 0.457 0.000
M19 Other arthrosis
0.542 0.457 0.000
M18 Arthrosis of first carpometacarpal joint
0.542 0.457 0.000
M15 Polyarthrosis
0.542 0.457 0.000
J90-J94 Other diseases of pleura
0.541 0.459 0.000
K29 Gastritis and duodenitis
0.541 0.459 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.541 0.459 0.000
K52 Other non-infective gastro-enteritis and colitis
0.540 0.460 0.000
E50-E64 Other nutritional deficiencies
0.538 0.462 0.000
E40-E46 Malnutrition
0.538 0.462 0.000
E20-E35 Disorders of other endocrine glands
0.538 0.462 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.538 0.462 0.000
R56.8 Other and unspecified convulsions
0.537 0.463 0.000
K51 Ulcerative colitis
0.537 0.463 0.000
L60-L75 Disorders of skin appendages
0.536 0.464 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.536 0.464 0.000
C50-C50 Malignant neoplasm of breast
0.535 0.465 0.000
R11 Nausea and vomiting
0.533 0.467 0.000
G47 Sleep disorders
0.533 0.467 0.000
I63 Cerebral infarction
0.531 0.469 0.000
M16.1 Other primary coxarthrosis
0.531 0.469 0.000
Chapter XXI Factors influencing health status and contact with health services
0.530 0.470 0.000
K40-K46 Hernia
0.529 0.471 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.529 0.471 0.000
R18 Ascites
0.529 0.471 0.000
R17 Unspecified jaundice
0.529 0.471 0.000
R14 Flatulence and related conditions
0.529 0.471 0.000
R12 Heartburn
0.529 0.471 0.000
N23 Unspecified renal colic
0.528 0.472 0.000
C60-C63 Malignant neoplasms of male genital organs
0.528 0.472 0.000
F30-F39 Mood [affective] disorders
0.526 0.474 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.523 0.476 0.000
L50-L54 Urticaria and erythema
0.523 0.476 0.000
L40-L45 Papulosquamous disorders
0.523 0.476 0.000
L10-L14 Bullous disorders
0.523 0.476 0.000
D80-D89 Certain disorders involving the immune mechanism
0.522 0.477 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.522 0.477 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.522 0.477 0.000
D55-D59 Haemolytic anaemias
0.522 0.477 0.000
M75.1 Rotator cuff syndrome
0.521 0.478 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.521 0.479 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.521 0.479 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.521 0.479 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.521 0.479 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.521 0.479 0.000
Y35-Y36 Legal intervention and operations of war
0.521 0.479 0.000
Y10-Y34 Event of undetermined intent
0.521 0.479 0.000
Y00-Y09 Assault
0.521 0.479 0.000
X85-X99 Assault
0.521 0.479 0.000
X60-X84 Intentional self-harm
0.521 0.479 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.521 0.479 0.000
X50-X57 Overexertion, travel and privation
0.521 0.479 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.521 0.479 0.000
X30-X39 Exposure to forces of nature
0.521 0.479 0.000
X20-X29 Contact with venomous animals and plants
0.521 0.479 0.000
X10-X19 Contact with heat and hot substances
0.521 0.479 0.000
X00-X09 Exposure to smoke, fire and flames
0.521 0.479 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.521 0.479 0.000
W75-W84 Other accidental threats to breathing
0.521 0.479 0.000
W65-W74 Accidental drowning and submersion
0.521 0.479 0.000
W50-W64 Exposure to animate mechanical forces
0.521 0.479 0.000
W20-W49 Exposure to inanimate mechanical forces
0.521 0.479 0.000
W00-W19 Falls
0.521 0.479 0.000
V98-V99 Other and unspecified transport accidents
0.521 0.479 0.000
V95-V97 Air and space transport accidents
0.521 0.479 0.000
V90-V94 Water transport accidents
0.521 0.479 0.000
V80-V89 Other land transport accidents
0.521 0.479 0.000
V70-V79 Bus occupant injured in transport accident
0.521 0.479 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.521 0.479 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.521 0.479 0.000
V40-V49 Car occupant injured in transport accident
0.521 0.479 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.521 0.479 0.000
V20-V29 Motorcycle rider injured in transport accident
0.521 0.479 0.000
V10-V19 Pedal cyclist injured in transport accident
0.521 0.479 0.000
V01-V09 Pedestrian injured in transport accident
0.521 0.479 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.520 0.480 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.520 0.480 0.000
M77 Other enthesopathies
0.520 0.480 0.000
M76 Enthesopathies of lower limb, excluding foot
0.520 0.480 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.520 0.480 0.000
M72 Fibroblastic disorders
0.520 0.480 0.000
M71 Other bursopathies
0.520 0.480 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.520 0.480 0.000
N40-N51 Diseases of male genital organs
0.519 0.481 0.000
S50-S59 Injuries to the elbow and forearm
0.518 0.482 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.517 0.483 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.513 0.487 0.000
T79-T79 Certain early complications of trauma
0.513 0.487 0.000
T66-T78 Other and unspecified effects of external causes
0.513 0.487 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.513 0.487 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.513 0.487 0.000
T33-T35 Frostbite
0.513 0.487 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.513 0.487 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.513 0.487 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.513 0.487 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.513 0.487 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.513 0.487 0.000
T00-T07 Injuries involving multiple body regions
0.513 0.487 0.000
S90-S99 Injuries to the ankle and foot
0.513 0.487 0.000
S80-S89 Injuries to the knee and lower leg
0.513 0.487 0.000
S70-S79 Injuries to the hip and thigh
0.513 0.487 0.000
S60-S69 Injuries to the wrist and hand
0.513 0.487 0.000
S40-S49 Injuries to the shoulder and upper arm
0.513 0.487 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.513 0.487 0.000
S20-S29 Injuries to the thorax
0.513 0.487 0.000
S10-S19 Injuries to the neck
0.513 0.487 0.000
S00-S09 Injuries to the head
0.513 0.487 0.000
C34 Malignant neoplasm of bronchus and lung
0.512 0.488 0.000
F99-F99 Unspecified mental disorder
0.511 0.489 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.511 0.489 0.000
F80-F89 Disorders of psychological development
0.511 0.489 0.000
F70-F79 Mental retardation
0.511 0.489 0.000
F60-F69 Disorders of adult personality and behaviour
0.511 0.489 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.511 0.489 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.511 0.489 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.511 0.489 0.000
G56 Mononeuropathies of upper limb
0.510 0.490 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.508 0.492 0.000
J22 Unspecified acute lower respiratory infection
0.508 0.492 0.000
R10.1 Pain localised to upper abdomen
0.507 0.493 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.506 0.493 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.506 0.494 0.000
M35 Other systemic involvement of connective tissue
0.506 0.494 0.000
M34 Systemic sclerosis
0.506 0.494 0.000
M33 Dermatopolymyositis
0.506 0.494 0.000
M32 Systemic lupus erythematosus
0.506 0.494 0.000
M31 Other necrotising vasculopathies
0.506 0.494 0.000
M30 Polyarteritis nodosa and related conditions
0.506 0.494 0.000
M25 Other joint disorders, not elsewhere classified
0.506 0.494 0.000
M24 Other specific joint derangements
0.506 0.494 0.000
M22 Disorders of patella
0.506 0.494 0.000
M21 Other acquired deformities of limbs
0.506 0.494 0.000
I24 Other acute ischaemic heart diseases
0.504 0.496 0.000
I23 Certain current complications following acute myocardial infarction
0.504 0.496 0.000
I22 Subsequent myocardial infarction
0.504 0.496 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.503 0.496 0.000
G44 Other headache syndromes
0.503 0.496 0.000
G43 Migraine
0.503 0.496 0.000
G41 Status epilepticus
0.503 0.496 0.000
R06 Abnormalities of breathing
0.503 0.497 0.000
M13 Other arthritis
0.502 0.498 0.000
K92.9 Disease of digestive system, unspecified
0.501 0.499 0.000
K92.8 Other specified diseases of digestive system
0.501 0.499 0.000
R10.4 Other and unspecified abdominal pain
0.501 0.499 0.000
R35 Polyuria
0.499 0.501 0.000
I83 Varicose veins of lower extremities
0.497 0.503 0.000
R50.8 Other specified fever
0.497 0.503 0.000
R50.2 Drug-induced fever
0.497 0.503 0.000
R50.1 Persistent fever
0.497 0.503 0.000
R50.0 Fever with chills
0.497 0.503 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.496 0.503 0.000
R04 Haemorrhage from respiratory passages
0.496 0.503 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.496 0.503 0.000
R01 Cardiac murmurs and other cardiac sounds
0.496 0.503 0.000
R05 Cough
0.496 0.503 0.000
R02 Gangrene, not elsewhere classified
0.496 0.503 0.000
R13 Dysphagia
0.496 0.504 0.000
R55 Syncope and collapse
0.496 0.504 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.494 0.505 0.000
K61 Abscess of anal and rectal regions
0.494 0.505 0.000
K60 Fissure and fistula of anal and rectal regions
0.494 0.505 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.494 0.505 0.000
K55 Vascular disorders of intestine
0.494 0.505 0.000
K50 Crohn's disease [regional enteritis]
0.493 0.507 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.492 0.508 0.000
G58 Other mononeuropathies
0.492 0.508 0.000
G57 Mononeuropathies of lower limb
0.492 0.508 0.000
G54 Nerve root and plexus disorders
0.492 0.508 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.492 0.508 0.000
G52 Disorders of other cranial nerves
0.492 0.508 0.000
G51 Facial nerve disorders
0.492 0.508 0.000
G50 Disorders of trigeminal nerve
0.492 0.508 0.000
A00-A09 Intestinal infectious diseases
0.492 0.508 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.492 0.508 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.491 0.508 0.000
E11 Non-insulin-dependent diabetes mellitus
0.491 0.509 0.000
E14 Unspecified diabetes mellitus
0.491 0.509 0.000
H30-H36 Disorders of choroid and retina
0.491 0.509 0.000
G37 Other demyelinating diseases of central nervous system
0.490 0.510 0.000
G36 Other acute disseminated demyelination
0.490 0.510 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.488 0.512 0.000
I88 Nonspecific lymphadenitis
0.488 0.512 0.000
I87 Other disorders of veins
0.488 0.512 0.000
I86 Varicose veins of other sites
0.488 0.512 0.000
I85 Oesophageal varices
0.488 0.512 0.000
I82 Other venous embolism and thrombosis
0.488 0.512 0.000
I80 Phlebitis and thrombophlebitis
0.488 0.512 0.000
I81 Portal vein thrombosis
0.488 0.512 0.000
M75.4 Impingement syndrome of shoulder
0.488 0.512 0.000
H40-H42 Glaucoma
0.487 0.513 0.000
A30-A49 Other bacterial diseases
0.487 0.513 0.000
E65-E68 Obesity and other hyperalimentation
0.486 0.514 0.000
N20.0 Calculus of kidney
0.485 0.515 0.000
R00.2 Palpitations
0.485 0.515 0.000
M51 Other intervertebral disk disorders
0.484 0.516 0.000
I26 Pulmonary embolism
0.483 0.517 0.000
I84.8 Unspecified haemorrhoids with other complications
0.482 0.518 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.480 0.520 0.000
M48 Other spondylopathies
0.479 0.520 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.479 0.521 0.000
N21 Calculus of lower urinary tract
0.479 0.521 0.000
J40-J47 Chronic lower respiratory diseases
0.479 0.521 0.000
B99-B99 Other infectious diseases
0.477 0.523 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.477 0.523 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.477 0.523 0.000
B65-B83 Helminthiases
0.477 0.523 0.000
B50-B64 Protozoal diseases
0.477 0.523 0.000
B35-B49 Mycoses
0.477 0.523 0.000
B25-B34 Other viral diseases
0.477 0.523 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.477 0.523 0.000
B15-B19 Viral hepatitis
0.477 0.523 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.477 0.523 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.477 0.523 0.000
A80-A89 Viral infections of the central nervous system
0.477 0.523 0.000
A75-A79 Rickettsioses
0.477 0.523 0.000
A70-A74 Other diseases caused by chlamydiae
0.477 0.523 0.000
A65-A69 Other spirochaetal diseases
0.477 0.523 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.477 0.523 0.000
A20-A28 Certain zoonotic bacterial diseases
0.477 0.523 0.000
A15-A19 Tuberculosis
0.477 0.523 0.000
R07 Pain in throat and chest
0.477 0.523 0.000
R42 Dizziness and giddiness
0.473 0.527 0.000
H90-H95 Other disorders of ear
0.472 0.528 0.000
H80-H83 Diseases of inner ear
0.472 0.528 0.000
H65-H75 Diseases of middle ear and mastoid
0.472 0.528 0.000
H60-H62 Diseases of external ear
0.472 0.528 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.472 0.528 0.000
O85-O92 Complications predominantly related to the puerperium
0.472 0.528 0.000
O80-O84 Delivery
0.472 0.528 0.000
O60-O75 Complications of labour and delivery
0.472 0.528 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.472 0.528 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.472 0.528 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.472 0.528 0.000
O00-O08 Pregnancy with abortive outcome
0.472 0.528 0.000
P90-P96 Other disorders originating in the perinatal period
0.472 0.528 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.472 0.528 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.472 0.528 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.472 0.528 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.472 0.528 0.000
P35-P39 Infections specific to the perinatal period
0.472 0.528 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.472 0.528 0.000
P10-P15 Birth trauma
0.472 0.528 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.472 0.528 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.472 0.528 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.472 0.528 0.000
Q80-Q89 Other congenital malformations
0.472 0.528 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.472 0.528 0.000
Q60-Q64 Congenital malformations of the urinary system
0.472 0.528 0.000
Q50-Q56 Congenital malformations of genital organs
0.472 0.528 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.472 0.528 0.000
Q35-Q37 Cleft lip and cleft palate
0.472 0.528 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.472 0.528 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.472 0.528 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.472 0.528 0.000
Q00-Q07 Congenital malformations of the nervous system
0.472 0.528 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.472 0.528 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.472 0.528 0.000
K57 Diverticular disease of intestine
0.470 0.529 0.000
M14 Arthropathies in other diseases classified elsewhere
0.470 0.530 0.000
M12 Other specific arthropathies
0.470 0.530 0.000
M11 Other crystal arthropathies
0.470 0.530 0.000
M10 Gout
0.470 0.530 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.470 0.530 0.000
M08 Juvenile arthritis
0.470 0.530 0.000
M07 Psoriatic and enteropathic arthropathies
0.470 0.530 0.000
M06 Other rheumatoid arthritis
0.470 0.530 0.000
M05 Seropositive rheumatoid arthritis
0.470 0.530 0.000
J18 Pneumonia, organism unspecified
0.470 0.530 0.000
H55-H59 Other disorders of eye and adnexa
0.469 0.531 0.000
H53-H54 Visual disturbances and blindness
0.469 0.531 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.469 0.531 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.469 0.531 0.000
H43-H45 Disorders of vitreous body and globe
0.469 0.531 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.469 0.531 0.000
H10-H13 Disorders of conjunctiva
0.469 0.531 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.469 0.531 0.000
I69 Sequelae of cerebrovascular disease
0.468 0.531 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.468 0.531 0.000
I67 Other cerebrovascular diseases
0.468 0.531 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.468 0.531 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.468 0.531 0.000
I62 Other nontraumatic intracranial haemorrhage
0.468 0.531 0.000
I61 Intracerebral haemorrhage
0.468 0.531 0.000
I60 Subarachnoid haemorrhage
0.468 0.531 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.468 0.531 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.468 0.532 0.000
E10 Insulin-dependent diabetes mellitus
0.467 0.533 0.000
K21 Gastro-oesophageal reflux disease
0.467 0.533 0.000
R94 Abnormal results of function studies
0.466 0.534 0.000
R32 Unspecified urinary incontinence
0.465 0.535 0.000
I10-I15 Hypertensive diseases
0.464 0.536 0.000
R10.3 Pain localised to other parts of lower abdomen
0.463 0.537 0.000
M54 Dorsalgia
0.463 0.537 0.000
M53 Other dorsopathies, not elsewhere classified
0.463 0.537 0.000
M50 Cervical disk disorders
0.463 0.537 0.000
R56.0 Febrile convulsions
0.462 0.537 0.000
T81 Complications of procedures, not elsewhere classified
0.462 0.538 0.000
M49 Spondylopathies in diseases classified elsewhere
0.461 0.539 0.000
M47 Spondylosis
0.461 0.539 0.000
M46 Other inflammatory spondylopathies
0.461 0.539 0.000
M45 Ankylosing spondylitis
0.461 0.539 0.000
C80 Malignant neoplasm without specification of site
0.461 0.539 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.461 0.539 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.461 0.539 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.461 0.539 0.000
B95-B98 Bacterial, viral and other infectious agents
0.460 0.540 0.000
R46 Symptoms and signs involving appearance and behaviour
0.459 0.541 0.000
R45 Symptoms and signs involving emotional state
0.459 0.541 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.459 0.541 0.000
R43 Disturbances of smell and taste
0.459 0.541 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.459 0.541 0.000
R40 Somnolence, stupor and coma
0.459 0.541 0.000
M20 Acquired deformities of fingers and toes
0.458 0.542 0.000
K02 Dental caries
0.457 0.543 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.456 0.544 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.456 0.544 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.456 0.544 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.456 0.544 0.000
K22 Other diseases of oesophagus
0.455 0.545 0.000
K31 Other diseases of stomach and duodenum
0.455 0.545 0.000
K28 Gastrojejunal ulcer
0.455 0.545 0.000
K27 Peptic ulcer, site unspecified
0.455 0.545 0.000
K26 Duodenal ulcer
0.455 0.545 0.000
K25 Gastric ulcer
0.455 0.545 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.455 0.545 0.000
M17.5 Other secondary gonarthrosis
0.452 0.548 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.452 0.548 0.000
M17.3 Other posttraumatic gonarthrosis
0.452 0.548 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.452 0.548 0.000
M17.0 Primary gonarthrosis, bilateral
0.452 0.548 0.000
K62.1 Rectal polyp
0.452 0.548 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.451 0.549 0.000
I84.6 Residual haemorrhoidal skin tags
0.451 0.549 0.000
I73 Other peripheral vascular diseases
0.450 0.550 0.000
L30 Other dermatitis
0.450 0.550 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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