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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111772174
log Bayes Factor = 12.5098
Chromosome 19   position 2,685,808  (GRCh37) Explore rs111772174 on Ensembl!
Variant rs111772174 is part of Cluster X0094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
I49 Other cardiac arrhythmias
0.986 0.014 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.986 0.014 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.984 0.016 0.000
Chapter XIV Diseases of the genitourinary system
0.981 0.019 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.980 0.020 0.000
A30-A49 Other bacterial diseases
0.975 0.025 0.000
C15-C26 Malignant neoplasms of digestive organs
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
C78.7 Secondary malignant neoplasm of liver
0.968 0.032 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.963 0.037 0.000
M05-M14 Inflammatory polyarthropathies
0.959 0.041 0.000
Chapter XXI Factors influencing health status and contact with health services
0.955 0.045 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.953 0.047 0.000
M70-M79 Other soft tissue disorders
0.952 0.048 0.000
A41 Other septicaemia
0.951 0.049 0.000
S60-S69 Injuries to the wrist and hand
0.948 0.052 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.945 0.055 0.000
I51 Complications and ill-defined descriptions of heart disease
0.942 0.058 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.938 0.062 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.937 0.063 0.000
M20-M25 Other joint disorders
0.937 0.063 0.000
N84 Polyp of female genital tract
0.936 0.064 0.000
B25-B34 Other viral diseases
0.935 0.065 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.935 0.065 0.000
A00-A09 Intestinal infectious diseases
0.934 0.066 0.000
I44 Atrioventricular and left bundle-branch block
0.934 0.066 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.933 0.067 0.000
B07 Viral warts
0.933 0.067 0.000
M79.8 Other specified soft tissue disorders
0.924 0.076 0.000
M23 Internal derangement of knee
0.924 0.076 0.000
G90-G99 Other disorders of the nervous system
0.923 0.077 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.921 0.079 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.919 0.081 0.000
A41.9 Septicaemia, unspecified
0.917 0.083 0.000
M23.3 Other meniscus derangements
0.913 0.087 0.000
A04 Other bacterial intestinal infections
0.913 0.087 0.000
Z90.7 Acquired absence of genital organ(s)
0.912 0.088 0.000
C78.0 Secondary malignant neoplasm of lung
0.910 0.090 0.000
I49.5 Sick sinus syndrome
0.910 0.090 0.000
N84.0 Polyp of corpus uteri
0.909 0.091 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.908 0.092 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.905 0.095 0.000
I49.0 Ventricular fibrillation and flutter
0.904 0.096 0.000
M13 Other arthritis
0.901 0.099 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.901 0.099 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.900 0.100 0.000
C16 Malignant neoplasm of stomach
0.896 0.104 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.895 0.105 0.000
B34 Viral infection of unspecified site
0.888 0.112 0.000
B02 Zoster [herpes zoster]
0.886 0.114 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.885 0.115 0.000
Z90.5 Acquired absence of kidney
0.885 0.115 0.000
V10-V19 Pedal cyclist injured in transport accident
0.883 0.117 0.000
E20-E35 Disorders of other endocrine glands
0.882 0.118 0.000
Z57 Occupational exposure to risk-factors
0.880 0.120 0.000
I49.9 Cardiac arrhythmia, unspecified
0.878 0.122 0.000
C64-C68 Malignant neoplasms of urinary tract
0.877 0.123 0.000
M86-M90 Other osteopathies
0.877 0.123 0.000
I26 Pulmonary embolism
0.873 0.127 0.000
N20-N23 Urolithiasis
0.870 0.130 0.000
N99-N99 Other disorders of the genitourinary system
0.870 0.130 0.000
M40-M43 Deforming dorsopathies
0.865 0.135 0.000
Z85 Personal history of malignant neoplasm
0.863 0.137 0.000
Z90.1 Acquired absence of breast(s)
0.862 0.138 0.000
C51-C58 Malignant neoplasms of female genital organs
0.861 0.139 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.859 0.141 0.000
G40-G47 Episodic and paroxysmal disorders
0.856 0.144 0.000
B34.9 Viral infection, unspecified
0.855 0.145 0.000
M13.9 Arthritis, unspecified
0.853 0.147 0.000
Z90.3 Acquired absence of part of stomach
0.852 0.148 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.852 0.148 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.851 0.149 0.000
S62 Fracture at wrist and hand level
0.851 0.149 0.000
I50 Heart failure
0.849 0.151 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.848 0.152 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.843 0.157 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.842 0.158 0.000
I42 Cardiomyopathy
0.841 0.159 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.841 0.159 0.000
N90.5 Atrophy of vulva
0.840 0.160 0.000
N10-N16 Renal tubulo-interstitial diseases
0.839 0.161 0.000
G93 Other disorders of brain
0.838 0.162 0.000
N95 Menopausal and other perimenopausal disorders
0.837 0.163 0.000
M23.8 Other internal derangements of knee
0.836 0.164 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.831 0.169 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.831 0.169 0.000
N17-N19 Renal failure
0.830 0.170 0.000
N23 Unspecified renal colic
0.830 0.170 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.827 0.173 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.826 0.174 0.000
S90-S99 Injuries to the ankle and foot
0.826 0.174 0.000
T93 Sequelae of injuries of lower limb
0.826 0.174 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.824 0.176 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.823 0.177 0.000
I05-I09 Chronic rheumatic heart diseases
0.822 0.178 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.822 0.178 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.820 0.180 0.000
S50-S59 Injuries to the elbow and forearm
0.819 0.181 0.000
C18 Malignant neoplasm of colon
0.817 0.183 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.816 0.184 0.000
I51.7 Cardiomegaly
0.815 0.185 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.814 0.186 0.000
M24 Other specific joint derangements
0.812 0.188 0.000
C25 Malignant neoplasm of pancreas
0.811 0.189 0.000
B15-B19 Viral hepatitis
0.810 0.190 0.000
Z57.2 Occupational exposure to dust
0.808 0.192 0.000
I44.1 Atrioventricular block, second degree
0.808 0.192 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.806 0.194 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.804 0.196 0.000
I27 Other pulmonary heart diseases
0.803 0.197 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.802 0.197 0.000
Z99.8 Dependence on other enabling machines and devices
0.799 0.201 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.799 0.201 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.799 0.201 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.798 0.202 0.000
M79.7 Fibromyalgia
0.795 0.205 0.000
I44.0 Atrioventricular block, first degree
0.793 0.207 0.000
I33 Acute and subacute endocarditis
0.792 0.207 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.792 0.208 0.000
Z97 Presence of other devices
0.792 0.208 0.000
I51.9 Heart disease, unspecified
0.791 0.209 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.790 0.210 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.790 0.210 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.790 0.210 0.000
S00-S09 Injuries to the head
0.789 0.211 0.000
Z99.1 Dependence on respirator
0.787 0.213 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.784 0.216 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.784 0.216 0.000
G47 Sleep disorders
0.784 0.216 0.000
V18.0 Driver injured in nontraffic accident
0.782 0.218 0.000
C56 Malignant neoplasm of ovary
0.782 0.218 0.000
I44.6 Other and unspecified fascicular block
0.780 0.220 0.000
C16.9 Stomach, unspecified
0.779 0.221 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.779 0.221 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.777 0.223 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.773 0.227 0.000
N93 Other abnormal uterine and vaginal bleeding
0.773 0.227 0.000
W50-W64 Exposure to animate mechanical forces
0.772 0.228 0.000
Z83 Family history of other specific disorders
0.772 0.228 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.771 0.229 0.000
N95.2 Postmenopausal atrophic vaginitis
0.770 0.230 0.000
W00-W19 Falls
0.769 0.231 0.000
C78.2 Secondary malignant neoplasm of pleura
0.769 0.231 0.000
C17 Malignant neoplasm of small intestine
0.769 0.231 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.769 0.231 0.000
G70-G73 Diseases of myoneural junction and muscle
0.766 0.234 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.766 0.234 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.766 0.234 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.766 0.234 0.000
Z63 Other problems related to primary support group, including family circumstances
0.763 0.237 0.000
A49 Bacterial infection of unspecified site
0.761 0.239 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.761 0.239 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.760 0.240 0.000
A04.5 Campylobacter enteritis
0.759 0.240 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.758 0.242 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.757 0.243 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.756 0.243 0.000
M41 Scoliosis
0.756 0.244 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.756 0.244 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.755 0.245 0.000
M45-M49 Spondylopathies
0.754 0.246 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.753 0.246 0.000
I45 Other conduction disorders
0.753 0.247 0.000
S80-S89 Injuries to the knee and lower leg
0.753 0.247 0.000
E23 Hypofunction and other disorders of pituitary gland
0.753 0.247 0.000
M10 Gout
0.751 0.249 0.000
I51.8 Other ill-defined heart diseases
0.749 0.251 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.747 0.253 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.747 0.253 0.000
N84.3 Polyp of vulva
0.747 0.253 0.000
I49.8 Other specified cardiac arrhythmias
0.746 0.254 0.000
I51.4 Myocarditis, unspecified
0.746 0.254 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.745 0.255 0.000
B02.9 Zoster without complication
0.744 0.256 0.000
S70-S79 Injuries to the hip and thigh
0.743 0.257 0.000
D00-D09 In situ neoplasms
0.743 0.257 0.000
B00 Herpesviral [herpes simplex] infections
0.743 0.257 0.000
C16.5 Lesser curvature of stomach, unspecified
0.741 0.259 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.740 0.260 0.000
Z56 Problems related to employment and unemployment
0.739 0.261 0.000
W20-W49 Exposure to inanimate mechanical forces
0.739 0.261 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.739 0.261 0.000
I49.4 Other and unspecified premature depolarisation
0.739 0.261 0.000
E22 Hyperfunction of pituitary gland
0.738 0.262 0.000
B02.2 Zoster with other nervous system involvement
0.737 0.263 0.000
M11 Other crystal arthropathies
0.737 0.263 0.000
I49.1 Atrial premature depolarisation
0.737 0.263 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.737 0.263 0.000
M07 Psoriatic and enteropathic arthropathies
0.736 0.264 0.000
I50.9 Heart failure, unspecified
0.735 0.265 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.734 0.266 0.000
Z97.8 Presence of other specified devices
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.733 0.267 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.732 0.268 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.732 0.268 0.000
M06 Other rheumatoid arthritis
0.731 0.269 0.000
I44.7 Left bundle-branch block, unspecified
0.731 0.269 0.000
N88 Other noninflammatory disorders of cervix uteri
0.730 0.270 0.000
N90.6 Hypertrophy of vulva
0.729 0.271 0.000
N84.1 Polyp of cervix uteri
0.729 0.271 0.000
Y57 Other and unspecified drugs and medicaments
0.728 0.272 0.000
M87 Osteonecrosis
0.726 0.274 0.000
V20-V29 Motorcycle rider injured in transport accident
0.726 0.274 0.000
C18.7 Sigmoid colon
0.726 0.274 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.725 0.275 0.000
S40-S49 Injuries to the shoulder and upper arm
0.724 0.276 0.000
M34 Systemic sclerosis
0.723 0.276 0.000
Z99.3 Dependence on wheelchair
0.721 0.279 0.000
N90.4 Leukoplakia of vulva
0.721 0.279 0.000
M65-M68 Disorders of synovium and tendon
0.721 0.279 0.000
C32 Malignant neoplasm of larynx
0.720 0.280 0.000
S01 Open wound of head
0.719 0.281 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.719 0.281 0.000
E29 Testicular dysfunction
0.718 0.282 0.000
V80-V89 Other land transport accidents
0.718 0.282 0.000
G91 Hydrocephalus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
Y86 Sequelae of other accidents
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.715 0.285 0.000
N13 Obstructive and reflux uropathy
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
S10-S19 Injuries to the neck
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
A02 Other Salmonella infections
0.712 0.288 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.712 0.288 0.000
C15 Malignant neoplasm of oesophagus
0.712 0.288 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.712 0.288 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.710 0.290 0.000
C16.0 Cardia
0.709 0.291 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.708 0.292 0.000
I49.2 Junctional premature depolarisation
0.707 0.293 0.000
S91 Open wound of ankle and foot
0.707 0.293 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.707 0.293 0.000
G47.9 Sleep disorder, unspecified
0.706 0.294 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.706 0.294 0.000
E50-E64 Other nutritional deficiencies
0.706 0.294 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.705 0.294 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.705 0.294 0.000
C80 Malignant neoplasm without specification of site
0.705 0.295 0.000
M80-M85 Disorders of bone density and structure
0.704 0.296 0.000
T79-T79 Certain early complications of trauma
0.704 0.296 0.000
M86 Osteomyelitis
0.703 0.297 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.703 0.297 0.000
D69 Purpura and other haemorrhagic conditions
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.703 0.297 0.000
B06 Rubella [German measles]
0.703 0.297 0.000
B05 Measles
0.703 0.297 0.000
B01 Varicella [chickenpox]
0.703 0.297 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.703 0.297 0.000
B04 Monkeypox
0.703 0.297 0.000
B03 Smallpox
0.703 0.297 0.000
G90 Disorders of autonomic nervous system
0.701 0.299 0.000
C18.6 Descending colon
0.701 0.299 0.000
S52 Fracture of forearm
0.701 0.299 0.000
G30-G32 Other degenerative diseases of the nervous system
0.700 0.300 0.000
G93.2 Benign intracranial hypertension
0.700 0.300 0.000
I05 Rheumatic mitral valve diseases
0.699 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.699 0.301 0.000
A48 Other bacterial diseases, not elsewhere classified
0.699 0.301 0.000
A44 Bartonellosis
0.699 0.301 0.000
A43 Nocardiosis
0.699 0.301 0.000
A42 Actinomycosis
0.699 0.301 0.000
A40 Streptococcal septicaemia
0.699 0.301 0.000
A39 Meningococcal infection
0.699 0.301 0.000
A37 Whooping cough
0.699 0.301 0.000
A36 Diphtheria
0.699 0.301 0.000
A32 Listeriosis
0.699 0.301 0.000
A31 Infection due to other mycobacteria
0.699 0.301 0.000
A30 Leprosy [Hansen's disease]
0.699 0.301 0.000
A46 Erysipelas
0.699 0.301 0.000
A38 Scarlet fever
0.699 0.301 0.000
A35 Other tetanus
0.699 0.301 0.000
A34 Obstetrical tetanus
0.699 0.301 0.000
A33 Tetanus neonatorum
0.699 0.301 0.000
M72 Fibroblastic disorders
0.699 0.301 0.000
N19 Unspecified renal failure
0.699 0.301 0.000
T91 Sequelae of injuries of neck and trunk
0.698 0.301 0.000
M25 Other joint disorders, not elsewhere classified
0.698 0.302 0.000
N00-N08 Glomerular diseases
0.698 0.302 0.000
E21.3 Hyperparathyroidism, unspecified
0.698 0.302 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.697 0.303 0.000
M89 Other disorders of bone
0.697 0.303 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.697 0.303 0.000
M91-M94 Chondropathies
0.697 0.303 0.000
D68 Other coagulation defects
0.696 0.304 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.696 0.304 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.695 0.305 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.695 0.305 0.000
C21 Malignant neoplasm of anus and anal canal
0.695 0.305 0.000
C23 Malignant neoplasm of gallbladder
0.695 0.305 0.000
M21 Other acquired deformities of limbs
0.695 0.305 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.695 0.305 0.000
D50-D53 Nutritional anaemias
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
M45 Ankylosing spondylitis
0.694 0.306 0.000
G44 Other headache syndromes
0.693 0.307 0.000
Z94 Transplanted organ and tissue status
0.692 0.308 0.000
S60 Superficial injury of wrist and hand
0.692 0.308 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.692 0.308 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.690 0.310 0.000
N98 Complications associated with artificial fertilisation
0.690 0.310 0.000
N91 Absent, scanty and rare menstruation
0.690 0.310 0.000
N82 Fistulae involving female genital tract
0.690 0.310 0.000
N96 Habitual aborter
0.690 0.310 0.000
N18 Chronic renal failure
0.689 0.311 0.000
G96 Other disorders of central nervous system
0.689 0.311 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.688 0.312 0.000
G50 Disorders of trigeminal nerve
0.688 0.312 0.000
M79.1 Myalgia
0.688 0.312 0.000
G81 Hemiplegia
0.688 0.312 0.000
M14 Arthropathies in other diseases classified elsewhere
0.687 0.313 0.000
M12 Other specific arthropathies
0.687 0.313 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.687 0.313 0.000
M08 Juvenile arthritis
0.687 0.313 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.687 0.313 0.000
Z89 Acquired absence of limb
0.687 0.313 0.000
Z98 Other postsurgical states
0.687 0.313 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.687 0.313 0.000
N86 Erosion and ectropion of cervix uteri
0.687 0.313 0.000
Z81 Family history of mental and behavioural disorders
0.686 0.314 0.000
B02.3 Zoster ocular disease
0.685 0.314 0.000
M13.0 Polyarthritis, unspecified
0.685 0.315 0.000
I42.9 Cardiomyopathy, unspecified
0.685 0.315 0.000
N90.3 Dysplasia of vulva, unspecified
0.683 0.317 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.683 0.317 0.000
N90.1 Moderate vulvar dysplasia
0.683 0.317 0.000
N90.0 Mild vulvar dysplasia
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.683 0.317 0.000
A04.8 Other specified bacterial intestinal infections
0.683 0.317 0.000
M76 Enthesopathies of lower limb, excluding foot
0.682 0.317 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.682 0.317 0.000
A41.4 Septicaemia due to anaerobes
0.682 0.318 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.682 0.318 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.682 0.318 0.000
Chapter XXII Codes for special purposes
0.682 0.318 0.000
Q60-Q64 Congenital malformations of the urinary system
0.680 0.320 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.680 0.320 0.000
S65 Injury of blood vessels at wrist and hand level
0.679 0.320 0.000
B95-B98 Bacterial, viral and other infectious agents
0.679 0.321 0.000
M71 Other bursopathies
0.679 0.321 0.000
G93.8 Other specified disorders of brain
0.679 0.321 0.000
M41.9 Scoliosis, unspecified
0.679 0.321 0.000
Chapter XI Diseases of the digestive system
0.677 0.323 0.000
I28 Other diseases of pulmonary vessels
0.677 0.323 0.000
T93.0 Sequelae of open wound of lower limb
0.677 0.323 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.677 0.323 0.000
C66 Malignant neoplasm of ureter
0.677 0.323 0.000
Z99.2 Dependence on renal dialysis
0.676 0.324 0.000
I46 Cardiac arrest
0.676 0.324 0.000
I51.6 Cardiovascular disease, unspecified
0.676 0.324 0.000
I51.5 Myocardial degeneration
0.676 0.324 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.676 0.324 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.676 0.324 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.676 0.324 0.000
I51.0 Cardiac septal defect, acquired
0.676 0.324 0.000
C50-C50 Malignant neoplasm of breast
0.675 0.325 0.000
S62.3 Fracture of other metacarpal bone
0.674 0.325 0.000
I27.2 Other secondary pulmonary hypertension
0.674 0.326 0.000
M79.0 Rheumatism, unspecified
0.674 0.326 0.000
I30 Acute pericarditis
0.674 0.326 0.000
Z96 Presence of other functional implants
0.674 0.326 0.000
G41 Status epilepticus
0.673 0.327 0.000
Z84 Family history of other conditions
0.673 0.327 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.673 0.327 0.000
G80 Infantile cerebral palsy
0.672 0.328 0.000
S62.4 Multiple fractures of metacarpal bones
0.672 0.328 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.672 0.328 0.000
M33 Dermatopolymyositis
0.672 0.328 0.000
M32 Systemic lupus erythematosus
0.672 0.328 0.000
M30 Polyarteritis nodosa and related conditions
0.672 0.328 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.671 0.328 0.000
N84.9 Polyp of female genital tract, unspecified
0.671 0.329 0.000
N84.8 Polyp of other parts of female genital tract
0.671 0.329 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.670 0.329 0.000
G58 Other mononeuropathies
0.670 0.330 0.000
B33 Other viral diseases, not elsewhere classified
0.670 0.330 0.000
B30 Viral conjunctivitis
0.670 0.330 0.000
B27 Infectious mononucleosis
0.670 0.330 0.000
B26 Mumps
0.670 0.330 0.000
B25 Cytomegaloviral disease
0.670 0.330 0.000
M79.9 Soft tissue disorder, unspecified
0.670 0.330 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.670 0.330 0.000
M79.3 Panniculitis, unspecified
0.670 0.330 0.000
M79.2 Neuralgia and neuritis, unspecified
0.670 0.330 0.000
I49.3 Ventricular premature depolarisation
0.670 0.330 0.000
A07 Other protozoal intestinal diseases
0.669 0.330 0.000
A06 Amoebiasis
0.669 0.330 0.000
A05 Other bacterial foodborne intoxications
0.669 0.330 0.000
A03 Shigellosis
0.669 0.330 0.000
A01 Typhoid and paratyphoid fevers
0.669 0.330 0.000
A00 Cholera
0.669 0.330 0.000
I44.5 Left posterior fascicular block
0.669 0.330 0.000
I44.4 Left anterior fascicular block
0.669 0.330 0.000
I44.3 Other and unspecified atrioventricular block
0.669 0.330 0.000
T86 Failure and rejection of transplanted organs and tissues
0.669 0.331 0.000
M70.6 Trochanteric bursitis
0.669 0.331 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.669 0.331 0.000
G93.3 Postviral fatigue syndrome
0.668 0.332 0.000
S67 Crushing injury of wrist and hand
0.668 0.332 0.000
I20-I25 Ischaemic heart diseases
0.667 0.333 0.000
T93.1 Sequelae of fracture of femur
0.667 0.333 0.000
M13.93 Arthritis, unspecified (Forearm)
0.666 0.334 0.000
S20-S29 Injuries to the thorax
0.665 0.334 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.665 0.335 0.000
S62.6 Fracture of other finger
0.665 0.335 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.665 0.335 0.000
E65-E68 Obesity and other hyperalimentation
0.664 0.336 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.663 0.336 0.000
N90.7 Vulvar cyst
0.663 0.337 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.663 0.337 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.663 0.337 0.000
E27 Other disorders of adrenal gland
0.663 0.337 0.000
M79.88 Other specified soft tissue disorders (Other)
0.662 0.337 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.662 0.337 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.662 0.337 0.000
M23.9 Internal derangement of knee, unspecified
0.662 0.338 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.662 0.338 0.000
M23.5 Chronic instability of knee
0.662 0.338 0.000
M23.1 Discoid meniscus (congenital)
0.662 0.338 0.000
M23.0 Cystic meniscus
0.662 0.338 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.662 0.338 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
G92 Toxic encephalopathy
0.662 0.338 0.000
G93.9 Disorder of brain, unspecified
0.662 0.338 0.000
I50.0 Congestive heart failure
0.662 0.338 0.000
C25.9 Pancreas, unspecified
0.662 0.338 0.000
S64 Injury of nerves at wrist and hand level
0.661 0.339 0.000
S62.5 Fracture of thumb
0.660 0.340 0.000
Z65 Problems related to other psychosocial circumstances
0.660 0.340 0.000
Z64 Problems related to certain psychosocial circumstances
0.660 0.340 0.000
Z62 Other problems related to upbringing
0.660 0.340 0.000
Z61 Problems related to negative life events in childhood
0.660 0.340 0.000
Z59 Problems related to housing and economic circumstances
0.660 0.340 0.000
Z58 Problems related to physical environment
0.660 0.340 0.000
Z55 Problems related to education and literacy
0.660 0.340 0.000
E23.0 Hypopituitarism
0.660 0.340 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.660 0.340 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.659 0.341 0.000
I83 Varicose veins of lower extremities
0.659 0.341 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.659 0.341 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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