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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112411280
log Bayes Factor = 15.0001
Chromosome 2   position 28,678,625  (GRCh37) Explore rs112411280 on Ensembl!
Variant rs112411280 is part of Cluster X0180

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
0.993 0.007 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
E14 Unspecified diabetes mellitus
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.983 0.017 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.982 0.018 0.000
Chapter XI Diseases of the digestive system
0.980 0.020 0.000
E14.9 Without complications
0.974 0.026 0.000
S00-S09 Injuries to the head
0.973 0.027 0.000
C15-C26 Malignant neoplasms of digestive organs
0.960 0.040 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.953 0.047 0.000
Chapter XX External causes of morbidity and mortality
0.949 0.051 0.000
K70-K77 Diseases of liver
0.947 0.053 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.947 0.053 0.000
S60-S69 Injuries to the wrist and hand
0.947 0.053 0.000
G90-G99 Other disorders of the nervous system
0.946 0.054 0.000
K90-K93 Other diseases of the digestive system
0.945 0.055 0.000
E10 Insulin-dependent diabetes mellitus
0.936 0.064 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.924 0.076 0.000
S00 Superficial injury of head
0.922 0.078 0.000
I20-I25 Ischaemic heart diseases
0.919 0.081 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.916 0.084 0.000
I74 Arterial embolism and thrombosis
0.916 0.084 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.915 0.085 0.000
K92 Other diseases of digestive system
0.913 0.087 0.000
F60-F69 Disorders of adult personality and behaviour
0.911 0.089 0.000
M45-M49 Spondylopathies
0.910 0.090 0.000
S10-S19 Injuries to the neck
0.908 0.092 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.907 0.093 0.000
M47 Spondylosis
0.907 0.093 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.905 0.095 0.000
I24 Other acute ischaemic heart diseases
0.902 0.098 0.000
K92.1 Melaena
0.901 0.099 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.901 0.099 0.000
I77 Other disorders of arteries and arterioles
0.898 0.102 0.000
C15 Malignant neoplasm of oesophagus
0.898 0.102 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.896 0.104 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.895 0.105 0.000
Chapter VII Diseases of the eye and adnexa
0.894 0.106 0.000
M47.8 Other spondylosis
0.886 0.114 0.000
I86 Varicose veins of other sites
0.884 0.116 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.884 0.116 0.000
I60-I69 Cerebrovascular diseases
0.881 0.119 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.877 0.123 0.000
K40-K46 Hernia
0.875 0.125 0.000
S20-S29 Injuries to the thorax
0.874 0.126 0.000
K74 Fibrosis and cirrhosis of liver
0.872 0.128 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.871 0.129 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.870 0.130 0.000
S60 Superficial injury of wrist and hand
0.868 0.132 0.000
M47.9 Spondylosis, unspecified
0.866 0.134 0.000
E10.3 With ophthalmic complications
0.865 0.135 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.864 0.136 0.000
S00.8 Superficial injury of other parts of head
0.864 0.136 0.000
C79 Secondary malignant neoplasm of other sites
0.863 0.137 0.000
S06 Intracranial injury
0.862 0.138 0.000
W20-W49 Exposure to inanimate mechanical forces
0.861 0.139 0.000
F60 Specific personality disorders
0.860 0.140 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.857 0.143 0.000
I22 Subsequent myocardial infarction
0.855 0.145 0.000
G40-G47 Episodic and paroxysmal disorders
0.855 0.145 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.854 0.146 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.852 0.148 0.000
H10-H13 Disorders of conjunctiva
0.848 0.152 0.000
S80-S89 Injuries to the knee and lower leg
0.847 0.153 0.000
E50-E64 Other nutritional deficiencies
0.846 0.154 0.000
S01 Open wound of head
0.843 0.157 0.000
I78 Diseases of capillaries
0.842 0.158 0.000
I86.4 Gastric varices
0.842 0.158 0.000
I77.1 Stricture of artery
0.840 0.160 0.000
Chapter XXII Codes for special purposes
0.836 0.164 0.000
E65-E68 Obesity and other hyperalimentation
0.835 0.165 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.834 0.166 0.000
K43 Ventral hernia
0.834 0.166 0.000
Chapter XXI Factors influencing health status and contact with health services
0.831 0.169 0.000
G91 Hydrocephalus
0.830 0.170 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.829 0.171 0.000
K70 Alcoholic liver disease
0.829 0.171 0.000
F10.0 Acute intoxication
0.829 0.171 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.825 0.175 0.000
S01.0 Open wound of scalp
0.823 0.177 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.822 0.178 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.821 0.179 0.000
C18 Malignant neoplasm of colon
0.821 0.179 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.820 0.180 0.000
F10.2 Dependence syndrome
0.815 0.185 0.000
I85 Oesophageal varices
0.815 0.185 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.814 0.186 0.000
K65-K67 Diseases of peritoneum
0.813 0.187 0.000
H11 Other disorders of conjunctiva
0.813 0.187 0.000
H00 Hordeolum and chalazion
0.811 0.189 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.809 0.191 0.000
Z12 Special screening examination for neoplasms
0.807 0.193 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.806 0.194 0.000
K04 Diseases of pulp and periapical tissues
0.806 0.194 0.000
T79-T79 Certain early complications of trauma
0.806 0.194 0.000
S50-S59 Injuries to the elbow and forearm
0.806 0.194 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.805 0.195 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.804 0.196 0.000
S00.9 Superficial injury of head, part unspecified
0.802 0.198 0.000
S12 Fracture of neck
0.800 0.200 0.000
T39.0 Salicylates
0.800 0.200 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.799 0.201 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.799 0.201 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.798 0.202 0.000
I24.8 Other forms of acute ischaemic heart disease
0.798 0.202 0.000
K42 Umbilical hernia
0.797 0.203 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.794 0.206 0.000
F60.9 Personality disorder, unspecified
0.794 0.206 0.000
I81 Portal vein thrombosis
0.792 0.208 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.792 0.208 0.000
X60-X84 Intentional self-harm
0.791 0.209 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.791 0.209 0.000
C15.5 Lower third of oesophagus
0.787 0.213 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.787 0.213 0.000
E11.8 With unspecified complications
0.786 0.213 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.786 0.214 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.785 0.215 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.785 0.215 0.000
K74.6 Other and unspecified cirrhosis of liver
0.783 0.217 0.000
T42.4 Benzodiazepines
0.783 0.217 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.783 0.217 0.000
S60.8 Other superficial injuries of wrist and hand
0.783 0.217 0.000
C15.9 Oesophagus, unspecified
0.781 0.219 0.000
E10.9 Without complications
0.778 0.222 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.778 0.222 0.000
I60 Subarachnoid haemorrhage
0.778 0.222 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.775 0.225 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.774 0.226 0.000
F80-F89 Disorders of psychological development
0.774 0.226 0.000
G70-G73 Diseases of myoneural junction and muscle
0.768 0.231 0.000
K70.9 Alcoholic liver disease, unspecified
0.768 0.232 0.000
S68 Traumatic amputation of wrist and hand
0.767 0.233 0.000
E11.2 With renal complications
0.767 0.233 0.000
Z04 Examination and observation for other reasons
0.766 0.234 0.000
I83 Varicose veins of lower extremities
0.766 0.234 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.766 0.234 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.765 0.234 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.763 0.237 0.000
E11.6 With other specified complications
0.762 0.238 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.762 0.238 0.000
G47 Sleep disorders
0.761 0.239 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.761 0.239 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.761 0.239 0.000
H04 Disorders of lachrymal system
0.760 0.240 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.758 0.242 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.758 0.242 0.000
H00.1 Chalazion
0.757 0.243 0.000
D10-D36 Benign neoplasms
0.757 0.243 0.000
I82 Other venous embolism and thrombosis
0.757 0.243 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.756 0.244 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.755 0.245 0.000
G62 Other polyneuropathies
0.755 0.245 0.000
D37.4 Colon
0.754 0.246 0.000
C18.2 Ascending colon
0.754 0.246 0.000
E14.3 With ophthalmic complications
0.753 0.247 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.753 0.247 0.000
S83.2 Tear of meniscus, current
0.751 0.249 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.750 0.250 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.749 0.250 0.000
T66-T78 Other and unspecified effects of external causes
0.748 0.252 0.000
F99-F99 Unspecified mental disorder
0.748 0.252 0.000
I99 Other and unspecified disorders of circulatory system
0.748 0.252 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.748 0.252 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.748 0.252 0.000
F10.3 Withdrawal state
0.748 0.252 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.746 0.253 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.746 0.254 0.000
I30-I52 Other forms of heart disease
0.745 0.255 0.000
S05 Injury of eye and orbit
0.744 0.256 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.744 0.256 0.000
V20-V29 Motorcycle rider injured in transport accident
0.744 0.256 0.000
G93 Other disorders of brain
0.743 0.257 0.000
T43.2 Other and unspecified antidepressants
0.743 0.257 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.742 0.258 0.000
I78.1 Naevus, nonneoplastic
0.742 0.258 0.000
K72 Hepatic failure, not elsewhere classified
0.741 0.259 0.000
M45 Ankylosing spondylitis
0.741 0.259 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.741 0.259 0.000
I87 Other disorders of veins
0.740 0.260 0.000
K92.0 Haematemesis
0.739 0.261 0.000
M47.82 Other spondylosis (Cervical region)
0.739 0.261 0.000
W29 Contact with other powered hand tools and household machinery
0.738 0.262 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.738 0.262 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.737 0.263 0.000
H11.0 Pterygium
0.737 0.263 0.000
I73 Other peripheral vascular diseases
0.736 0.264 0.000
K05 Gingivitis and periodontal diseases
0.735 0.265 0.000
S32 Fracture of lumbar spine and pelvis
0.735 0.265 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.732 0.268 0.000
K04.7 Periapical abscess without sinus
0.732 0.268 0.000
V40-V49 Car occupant injured in transport accident
0.732 0.268 0.000
H02 Other disorders of eyelid
0.731 0.269 0.000
I72 Other aneurysm
0.729 0.271 0.000
T18 Foreign body in alimentary tract
0.729 0.271 0.000
S06.0 Concussion
0.729 0.271 0.000
Chapter I Certain infectious and parasitic diseases
0.727 0.273 0.000
F60.3 Emotionally unstable personality disorder
0.727 0.273 0.000
S14 Injury of nerves and spinal cord at neck level
0.726 0.273 0.000
S64 Injury of nerves at wrist and hand level
0.725 0.275 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.725 0.275 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.723 0.276 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.723 0.277 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.722 0.277 0.000
S00.3 Superficial injury of nose
0.721 0.279 0.000
G96 Other disorders of central nervous system
0.721 0.279 0.000
G47.9 Sleep disorder, unspecified
0.719 0.281 0.000
M47.89 Other spondylosis (Site unspecified)
0.719 0.281 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.718 0.282 0.000
C60-C63 Malignant neoplasms of male genital organs
0.718 0.282 0.000
G91.9 Hydrocephalus, unspecified
0.717 0.283 0.000
E66 Obesity
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M47.86 Other spondylosis (Lumbar region)
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C79.2 Secondary malignant neoplasm of skin
0.717 0.283 0.000
I69 Sequelae of cerebrovascular disease
0.715 0.285 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.715 0.285 0.000
Z57 Occupational exposure to risk-factors
0.715 0.285 0.000
E13 Other specified diabetes mellitus
0.714 0.286 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.714 0.286 0.000
T19 Foreign body in genito-urinary tract
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
E55 Vitamin D deficiency
0.712 0.288 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.288 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.288 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.288 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.288 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.288 0.000
T36 Poisoning by systemic antibiotics
0.711 0.288 0.000
S12.7 Multiple fractures of cervical spine
0.710 0.290 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.710 0.290 0.000
G95 Other diseases of spinal cord
0.709 0.291 0.000
Z04.3 Examination and observation following other accident
0.709 0.291 0.000
C21 Malignant neoplasm of anus and anal canal
0.708 0.292 0.000
M91-M94 Chondropathies
0.708 0.292 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.707 0.292 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.707 0.293 0.000
E10.2 With renal complications
0.707 0.293 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.707 0.293 0.000
E14.8 With unspecified complications
0.707 0.293 0.000
E14.7 With multiple complications
0.707 0.293 0.000
E14.6 With other specified complications
0.707 0.293 0.000
E14.5 With peripheral circulatory complications
0.707 0.293 0.000
E14.4 With neurological complications
0.707 0.293 0.000
E14.2 Withrenal complications
0.707 0.293 0.000
E14.1 With ketoacidosis
0.707 0.293 0.000
E14.0 With coma
0.707 0.293 0.000
F30-F39 Mood [affective] disorders
0.706 0.294 0.000
I74.5 Embolism and thrombosis of iliac artery
0.706 0.294 0.000
K02 Dental caries
0.706 0.294 0.000
Z60 Problems related to social environment
0.706 0.294 0.000
I22.8 Subsequent myocardial infarction of other sites
0.706 0.294 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.705 0.295 0.000
E11.1 With ketoacidosis
0.705 0.295 0.000
F11 Mental and behavioural disorders due to use of opioids
0.705 0.295 0.000
W22 Striking against or struck by other objects
0.705 0.295 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.705 0.295 0.000
F70-F79 Mental retardation
0.705 0.295 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.705 0.295 0.000
D46 Myelodysplastic syndromes
0.705 0.295 0.000
I61 Intracerebral haemorrhage
0.704 0.295 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.704 0.296 0.000
K66 Other disorders of peritoneum
0.703 0.297 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.703 0.297 0.000
M00-M03 Infectious arthropathies
0.701 0.299 0.000
T40.2 Other opioids
0.701 0.299 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.700 0.300 0.000
I70 Atherosclerosis
0.699 0.301 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.698 0.302 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.698 0.302 0.000
M49 Spondylopathies in diseases classified elsewhere
0.698 0.302 0.000
S08 Traumatic amputation of part of head
0.697 0.302 0.000
S07 Crushing injury of head
0.697 0.302 0.000
S04 Injury of cranial nerves
0.697 0.302 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.697 0.302 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.697 0.303 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.697 0.303 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.697 0.303 0.000
I35 Nonrheumatic aortic valve disorders
0.697 0.303 0.000
K91.4 Colostomy and enterostomy malfunction
0.697 0.303 0.000
C51-C58 Malignant neoplasms of female genital organs
0.696 0.304 0.000
C71 Malignant neoplasm of brain
0.695 0.305 0.000
K76 Other diseases of liver
0.695 0.305 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.693 0.307 0.000
K35-K38 Diseases of appendix
0.692 0.308 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.692 0.308 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.692 0.308 0.000
S40-S49 Injuries to the shoulder and upper arm
0.691 0.309 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.689 0.311 0.000
I85.9 Oesophageal varices without bleeding
0.689 0.311 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.689 0.311 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.689 0.311 0.000
C17 Malignant neoplasm of small intestine
0.689 0.311 0.000
C23 Malignant neoplasm of gallbladder
0.689 0.311 0.000
D27 Benign neoplasm of ovary
0.688 0.312 0.000
G37 Other demyelinating diseases of central nervous system
0.688 0.312 0.000
S69 Other and unspecified injuries of wrist and hand
0.687 0.313 0.000
H53-H54 Visual disturbances and blindness
0.687 0.313 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.686 0.314 0.000
I62 Other nontraumatic intracranial haemorrhage
0.686 0.314 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.685 0.315 0.000
D48.7 Other specified sites
0.684 0.316 0.000
G81 Hemiplegia
0.684 0.316 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.684 0.316 0.000
K75 Other inflammatory liver diseases
0.684 0.316 0.000
I88 Nonspecific lymphadenitis
0.683 0.317 0.000
D45 Polycythaemia vera
0.683 0.317 0.000
I51 Complications and ill-defined descriptions of heart disease
0.683 0.317 0.000
H55-H59 Other disorders of eye and adnexa
0.683 0.317 0.000
W44 Foreign body entering into or through eye or natural orifice
0.681 0.319 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.681 0.319 0.000
E53 Deficiency of other B group vitamins
0.681 0.319 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.681 0.319 0.000
Y35-Y36 Legal intervention and operations of war
0.681 0.319 0.000
Y10-Y34 Event of undetermined intent
0.681 0.319 0.000
Y00-Y09 Assault
0.681 0.319 0.000
X85-X99 Assault
0.681 0.319 0.000
X50-X57 Overexertion, travel and privation
0.681 0.319 0.000
X30-X39 Exposure to forces of nature
0.681 0.319 0.000
X20-X29 Contact with venomous animals and plants
0.681 0.319 0.000
X10-X19 Contact with heat and hot substances
0.681 0.319 0.000
X00-X09 Exposure to smoke, fire and flames
0.681 0.319 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.681 0.319 0.000
W75-W84 Other accidental threats to breathing
0.681 0.319 0.000
W65-W74 Accidental drowning and submersion
0.681 0.319 0.000
W50-W64 Exposure to animate mechanical forces
0.681 0.319 0.000
V98-V99 Other and unspecified transport accidents
0.681 0.319 0.000
V95-V97 Air and space transport accidents
0.681 0.319 0.000
V90-V94 Water transport accidents
0.681 0.319 0.000
V70-V79 Bus occupant injured in transport accident
0.681 0.319 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.681 0.319 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.681 0.319 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.681 0.319 0.000
V01-V09 Pedestrian injured in transport accident
0.681 0.319 0.000
D37.1 Stomach
0.680 0.320 0.000
K74.5 Biliary cirrhosis, unspecified
0.680 0.320 0.000
K77 Liver disorders in diseases classified elsewhere
0.679 0.321 0.000
K73 Chronic hepatitis, not elsewhere classified
0.679 0.321 0.000
K71 Toxic liver disease
0.679 0.321 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.679 0.321 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.679 0.321 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.679 0.321 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.679 0.321 0.000
S65 Injury of blood vessels at wrist and hand level
0.679 0.321 0.000
M65-M68 Disorders of synovium and tendon
0.679 0.321 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.679 0.321 0.000
G90 Disorders of autonomic nervous system
0.679 0.321 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.679 0.321 0.000
G92 Toxic encephalopathy
0.679 0.321 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.677 0.322 0.000
K74.0 Hepatic fibrosis
0.677 0.322 0.000
S06.9 Intracranial injury, unspecified
0.677 0.323 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.676 0.323 0.000
K91.3 Postoperative intestinal obstruction
0.676 0.324 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.676 0.324 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.675 0.325 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.674 0.326 0.000
K76.6 Portal hypertension
0.674 0.326 0.000
C15.4 Middle third of oesophagus
0.673 0.327 0.000
S06.5 Traumatic subdural haemorrhage
0.673 0.327 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.672 0.328 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.671 0.328 0.000
Z01.4 Gynaecological examination (general)(routine)
0.671 0.329 0.000
E10.8 With unspecified complications
0.671 0.329 0.000
E10.7 With multiple complications
0.671 0.329 0.000
E10.6 With other specified complications
0.671 0.329 0.000
E10.0 With coma
0.671 0.329 0.000
V80-V89 Other land transport accidents
0.671 0.329 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.671 0.329 0.000
M47.1 Other spondylosis with myelopathy
0.670 0.329 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.670 0.330 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.670 0.330 0.000
K00 Disorders of tooth development and eruption
0.669 0.331 0.000
E10.5 With peripheral circulatory complications
0.669 0.331 0.000
S27 Injury of other and unspecified intrathoracic organs
0.669 0.331 0.000
M80-M85 Disorders of bone density and structure
0.668 0.332 0.000
S00.0 Superficial injury of scalp
0.668 0.332 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.667 0.333 0.000
Z57.2 Occupational exposure to dust
0.666 0.334 0.000
T86 Failure and rejection of transplanted organs and tissues
0.665 0.335 0.000
S19 Other and unspecified injuries of neck
0.664 0.336 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.664 0.336 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.664 0.336 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.664 0.336 0.000
S20 Superficial injury of thorax
0.664 0.336 0.000
D23 Other benign neoplasms of skin
0.664 0.336 0.000
D24 Benign neoplasm of breast
0.663 0.337 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.662 0.338 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.662 0.338 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.662 0.338 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.662 0.338 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.662 0.338 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.662 0.338 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.662 0.338 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.661 0.338 0.000
H02.8 Other specified disorders of eyelid
0.661 0.339 0.000
C79.6 Secondary malignant neoplasm of ovary
0.661 0.339 0.000
S00.7 Multiple superficial injuries of head
0.661 0.339 0.000
S00.5 Superficial injury of lip and oral cavity
0.661 0.339 0.000
S00.4 Superficial injury of ear
0.661 0.339 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.661 0.339 0.000
I23 Certain current complications following acute myocardial infarction
0.659 0.341 0.000
K01 Embedded and impacted teeth
0.659 0.341 0.000
Q80-Q89 Other congenital malformations
0.658 0.342 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.658 0.342 0.000
I77.8 Other specified disorders of arteries and arterioles
0.657 0.343 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.657 0.343 0.000
Z04.8 Examination and observation for other specified reasons
0.657 0.343 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.657 0.343 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.657 0.343 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.657 0.343 0.000
T42.3 Barbiturates
0.657 0.343 0.000
T42.2 Succinimides and oxazolidinediones
0.657 0.343 0.000
T42.1 Iminostilbenes
0.657 0.343 0.000
T42.0 Hydantoin derivatives
0.657 0.343 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.657 0.343 0.000
I74.8 Embolism and thrombosis of other arteries
0.657 0.343 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.657 0.343 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.657 0.343 0.000
A30-A49 Other bacterial diseases
0.656 0.344 0.000
M60-M63 Disorders of muscles
0.656 0.344 0.000
I51.8 Other ill-defined heart diseases
0.655 0.345 0.000
G91.1 Obstructive hydrocephalus
0.655 0.345 0.000
K92.8 Other specified diseases of digestive system
0.654 0.345 0.000
Z01.6 Radiological examination, not elsewhere classified
0.654 0.346 0.000
D37.7 Other digestive organs
0.654 0.346 0.000
F68 Other disorders of adult personality and behaviour
0.653 0.346 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.653 0.346 0.000
F65 Disorders of sexual preference
0.653 0.346 0.000
F64 Gender identity disorders
0.653 0.346 0.000
F63 Habit and impulse disorders
0.653 0.346 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.653 0.346 0.000
F69 Unspecified disorder of adult personality and behaviour
0.653 0.346 0.000
F61 Mixed and other personality disorders
0.653 0.346 0.000
F10.4 Withdrawal state with delirium
0.653 0.347 0.000
I60.8 Other subarachnoid haemorrhage
0.653 0.347 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.653 0.347 0.000
M86-M90 Other osteopathies
0.653 0.347 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.653 0.347 0.000
S61 Open wound of wrist and hand
0.652 0.348 0.000
S86 Injury of muscle and tendon at lower leg level
0.651 0.348 0.000
S17 Crushing injury of neck
0.651 0.349 0.000
S15 Injury of blood vessels at neck level
0.651 0.349 0.000
S11 Open wound of neck
0.651 0.349 0.000
S10 Superficial injury of neck
0.651 0.349 0.000
S18 Traumatic amputation at neck level
0.651 0.349 0.000
S16 Injury of muscle and tendon at neck level
0.651 0.349 0.000
K05.3 Chronic periodontitis
0.651 0.349 0.000
K70.0 Alcoholic fatty liver
0.651 0.349 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.650 0.350 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.650 0.350 0.000
W29.9 Unspecified place
0.650 0.350 0.000
S62 Fracture at wrist and hand level
0.650 0.350 0.000
E10.4 With neurological complications
0.649 0.351 0.000
C43 Malignant melanoma of skin
0.649 0.351 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.649 0.351 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.649 0.351 0.000
S37 Injury of urinary and pelvic organs
0.649 0.351 0.000
S36 Injury of intra-abdominal organs
0.649 0.351 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.649 0.351 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.649 0.351 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.649 0.351 0.000
S31 Open wound of abdomen, lower back and pelvis
0.649 0.351 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.649 0.351 0.000
E66.9 Obesity, unspecified
0.648 0.352 0.000
G30-G32 Other degenerative diseases of the nervous system
0.648 0.352 0.000
Z60.2 Living alone
0.648 0.352 0.000
C77.0 Lymph nodes of head, face and neck
0.648 0.352 0.000
H11.8 Other specified disorders of conjunctiva
0.647 0.353 0.000
M47.2 Other spondylosis with radiculopathy
0.647 0.353 0.000
I05-I09 Chronic rheumatic heart diseases
0.647 0.353 0.000
I24.1 Dressler's syndrome
0.646 0.354 0.000
S67 Crushing injury of wrist and hand
0.646 0.354 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.646 0.354 0.000
S12.70 Multiple fractures of cervical spine (closed)
0.646 0.354 0.000
D37.5 Rectum
0.646 0.354 0.000
F10.9 Unspecified mental and behavioural disorder
0.646 0.354 0.000
F10.8 Other mental and behavioural disorders
0.646 0.354 0.000
F10.7 Residual and late-onset psychotic disorder
0.646 0.354 0.000
F10.6 Amnesic syndrome
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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