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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112509438
log Bayes Factor = 20.2341
Chromosome 4   position 5,374,450  (GRCh37) Explore rs112509438 on Ensembl!
Variant rs112509438 is part of Cluster X0094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
Chapter II Neoplasms
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
J47 Bronchiectasis
0.992 0.008 0.000
Chapter V Mental and behavioural disorders
0.992 0.008 0.000
R50-R69 General symptoms and signs
0.987 0.013 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.983 0.017 0.000
Chapter I Certain infectious and parasitic diseases
0.983 0.017 0.000
J30-J39 Other diseases of upper respiratory tract
0.981 0.019 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.981 0.019 0.000
Chapter VIII Diseases of the ear and mastoid process
0.977 0.023 0.000
T81 Complications of procedures, not elsewhere classified
0.975 0.025 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.974 0.026 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.974 0.026 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.970 0.030 0.000
F17.1 Harmful use
0.967 0.033 0.000
R51 Headache
0.966 0.034 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.964 0.036 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.963 0.037 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.962 0.038 0.000
Z72 Problems related to lifestyle
0.958 0.042 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.958 0.042 0.000
Chapter XI Diseases of the digestive system
0.953 0.047 0.000
J90-J94 Other diseases of pleura
0.950 0.050 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.946 0.054 0.000
Z72.0 Tobacco use
0.946 0.054 0.000
R10 Abdominal and pelvic pain
0.941 0.059 0.000
J43 Emphysema
0.939 0.061 0.000
H90-H95 Other disorders of ear
0.938 0.062 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.938 0.062 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.929 0.071 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.928 0.072 0.000
M05-M14 Inflammatory polyarthropathies
0.928 0.072 0.000
M70-M79 Other soft tissue disorders
0.926 0.074 0.000
J09-J18 Influenza and pneumonia
0.926 0.074 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.922 0.078 0.000
J34 Other disorders of nose and nasal sinuses
0.920 0.080 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.920 0.080 0.000
C15-C26 Malignant neoplasms of digestive organs
0.914 0.086 0.000
B95-B98 Bacterial, viral and other infectious agents
0.913 0.087 0.000
R63 Symptoms and signs concerning food and fluid intake
0.908 0.092 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.906 0.094 0.000
M06 Other rheumatoid arthritis
0.905 0.095 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.904 0.096 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.903 0.097 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.902 0.098 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.899 0.101 0.000
K50-K52 Noninfective enteritis and colitis
0.898 0.102 0.000
J43.9 Emphysema, unspecified
0.896 0.104 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.893 0.107 0.000
R10.3 Pain localised to other parts of lower abdomen
0.890 0.110 0.000
S60-S69 Injuries to the wrist and hand
0.889 0.111 0.000
E70-E90 Metabolic disorders
0.889 0.111 0.000
D00-D09 In situ neoplasms
0.885 0.115 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.884 0.116 0.000
C77.2 Intra-abdominal lymph nodes
0.884 0.116 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.884 0.116 0.000
A30-A49 Other bacterial diseases
0.881 0.119 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.880 0.120 0.000
M80-M85 Disorders of bone density and structure
0.878 0.122 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.876 0.124 0.000
R50 Fever of unknown origin
0.876 0.124 0.000
H91 Other hearing loss
0.875 0.125 0.000
M06.9 Rheumatoid arthritis, unspecified
0.874 0.126 0.000
M20-M25 Other joint disorders
0.874 0.126 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.865 0.135 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.865 0.135 0.000
Y43 Primarily systemic agents
0.864 0.136 0.000
Chapter VI Diseases of the nervous system
0.864 0.136 0.000
K51 Ulcerative colitis
0.863 0.137 0.000
K55-K64 Other diseases of intestines
0.862 0.138 0.000
R52 Pain, not elsewhere classified
0.860 0.140 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.857 0.143 0.000
R03.1 Nonspecific low blood-pressure reading
0.857 0.143 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.855 0.145 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.855 0.145 0.000
Z51 Other medical care
0.854 0.146 0.000
J32 Chronic sinusitis
0.852 0.148 0.000
Z29 Need for other prophylactic measures
0.849 0.151 0.000
J90 Pleural effusion, not elsewhere classified
0.847 0.153 0.000
J35 Chronic diseases of tonsils and adenoids
0.846 0.154 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.845 0.155 0.000
Z45 Adjustment and management of implanted device
0.843 0.157 0.000
T81.9 Unspecified complication of procedure
0.834 0.166 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.834 0.166 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.831 0.169 0.000
H91.9 Hearing loss, unspecified
0.831 0.169 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.831 0.169 0.000
S20-S29 Injuries to the thorax
0.830 0.169 0.000
H65-H75 Diseases of middle ear and mastoid
0.830 0.170 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.830 0.170 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.829 0.171 0.000
K62 Other diseases of anus and rectum
0.825 0.175 0.000
Y43.3 Other antineoplastic drugs
0.824 0.176 0.000
Chapter XIV Diseases of the genitourinary system
0.822 0.178 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.822 0.178 0.000
M72 Fibroblastic disorders
0.821 0.179 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.820 0.180 0.000
M65-M68 Disorders of synovium and tendon
0.820 0.180 0.000
Z51.5 Palliative care
0.819 0.181 0.000
Chapter XXII Codes for special purposes
0.818 0.182 0.000
K35-K38 Diseases of appendix
0.818 0.182 0.000
R10.4 Other and unspecified abdominal pain
0.817 0.183 0.000
F17.2 Dependence syndrome
0.817 0.183 0.000
E87.5 Hyperkalaemia
0.815 0.185 0.000
R17 Unspecified jaundice
0.814 0.186 0.000
J34.3 Hypertrophy of nasal turbinates
0.814 0.186 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.813 0.187 0.000
R23 Other skin changes
0.813 0.187 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.811 0.189 0.000
C34 Malignant neoplasm of bronchus and lung
0.809 0.191 0.000
K62.1 Rectal polyp
0.808 0.192 0.000
Z51.1 Chemotherapy session for neoplasm
0.808 0.192 0.000
Z48 Other surgical follow-up care
0.805 0.195 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.805 0.195 0.000
A41 Other septicaemia
0.804 0.196 0.000
C18 Malignant neoplasm of colon
0.803 0.196 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.803 0.197 0.000
R53 Malaise and fatigue
0.803 0.197 0.000
R10.1 Pain localised to upper abdomen
0.800 0.200 0.000
J36 Peritonsillar abscess
0.799 0.201 0.000
Z41 Procedures for purposes other than remedying health state
0.799 0.201 0.000
K81 Cholecystitis
0.798 0.202 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.798 0.202 0.000
J18 Pneumonia, organism unspecified
0.797 0.203 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.792 0.208 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.791 0.209 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.789 0.211 0.000
R11 Nausea and vomiting
0.788 0.212 0.000
R63.4 Abnormal weight loss
0.787 0.213 0.000
R04 Haemorrhage from respiratory passages
0.786 0.214 0.000
Z43 Attention to artificial openings
0.785 0.215 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.785 0.215 0.000
R50.9 Fever, unspecified
0.784 0.216 0.000
K85 Acute pancreatitis
0.784 0.216 0.000
K51.9 Ulcerative colitis, unspecified
0.784 0.216 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.781 0.218 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.778 0.222 0.000
J93 Pneumothorax
0.776 0.224 0.000
Z22 Carrier of infectious disease
0.775 0.225 0.000
M31 Other necrotising vasculopathies
0.775 0.225 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.775 0.225 0.000
S64 Injury of nerves at wrist and hand level
0.774 0.226 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.773 0.227 0.000
A00-A09 Intestinal infectious diseases
0.773 0.227 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.773 0.227 0.000
Z72.1 Alcohol use
0.773 0.227 0.000
M84 Disorders of continuity of bone
0.772 0.228 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.772 0.228 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.772 0.228 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.772 0.228 0.000
J46 Status asthmaticus
0.772 0.228 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.772 0.228 0.000
E87.6 Hypokalaemia
0.771 0.229 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.770 0.230 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.770 0.230 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.770 0.230 0.000
J91 Pleural effusion in conditions classified elsewhere
0.770 0.230 0.000
H93 Other disorders of ear, not elsewhere classified
0.769 0.231 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.769 0.231 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.768 0.232 0.000
E87.0 Hyperosmolality and hypernatraemia
0.768 0.232 0.000
Z50 Care involving use of rehabilitation procedures
0.767 0.233 0.000
J34.2 Deviated nasal septum
0.767 0.233 0.000
M40-M43 Deforming dorsopathies
0.766 0.234 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.765 0.235 0.000
M06.0 Seronegative rheumatoid arthritis
0.764 0.236 0.000
G90-G99 Other disorders of the nervous system
0.760 0.240 0.000
H60-H62 Diseases of external ear
0.760 0.240 0.000
C20 Malignant neoplasm of rectum
0.760 0.240 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.760 0.240 0.000
R15 Faecal incontinence
0.759 0.241 0.000
T86 Failure and rejection of transplanted organs and tissues
0.758 0.242 0.000
F80-F89 Disorders of psychological development
0.757 0.243 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.757 0.243 0.000
R57 Shock, not elsewhere classified
0.757 0.243 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.756 0.244 0.000
T66-T78 Other and unspecified effects of external causes
0.753 0.247 0.000
R01 Cardiac murmurs and other cardiac sounds
0.753 0.247 0.000
R94 Abnormal results of function studies
0.752 0.248 0.000
H92 Otalgia and effusion of ear
0.751 0.249 0.000
C64-C68 Malignant neoplasms of urinary tract
0.749 0.251 0.000
A41.9 Septicaemia, unspecified
0.749 0.251 0.000
N40-N51 Diseases of male genital organs
0.749 0.251 0.000
M86-M90 Other osteopathies
0.748 0.252 0.000
K65-K67 Diseases of peritoneum
0.748 0.252 0.000
J40 Bronchitis, not specified as acute or chronic
0.748 0.252 0.000
K40-K46 Hernia
0.747 0.253 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.747 0.253 0.000
M35 Other systemic involvement of connective tissue
0.746 0.254 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.746 0.254 0.000
C77.3 Axillary and upper limb lymph nodes
0.745 0.255 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.745 0.255 0.000
D07.5 Prostate
0.745 0.255 0.000
R04.0 Epistaxis
0.742 0.258 0.000
C77.9 Lymph node, unspecified
0.742 0.258 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.742 0.258 0.000
Z45.2 Adjustment and management of vascular access device
0.739 0.261 0.000
M91-M94 Chondropathies
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.737 0.263 0.000
J00-J06 Acute upper respiratory infections
0.736 0.264 0.000
Z49 Care involving dialysis
0.736 0.264 0.000
C77.4 Inguinal and lower limb lymph nodes
0.736 0.264 0.000
L50-L54 Urticaria and erythema
0.736 0.264 0.000
V80-V89 Other land transport accidents
0.735 0.265 0.000
D45 Polycythaemia vera
0.734 0.266 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.734 0.266 0.000
E87.2 Acidosis
0.732 0.268 0.000
Z47 Other orthopaedic follow-up care
0.732 0.268 0.000
B15-B19 Viral hepatitis
0.732 0.268 0.000
B35-B49 Mycoses
0.732 0.268 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.730 0.269 0.000
J94 Other pleural conditions
0.729 0.271 0.000
R18 Ascites
0.728 0.272 0.000
J32.8 Other chronic sinusitis
0.727 0.273 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.275 0.000
S61 Open wound of wrist and hand
0.725 0.275 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.725 0.275 0.000
C77.8 Lymph nodes of multiple regions
0.725 0.275 0.000
W00-W19 Falls
0.723 0.277 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.723 0.277 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.722 0.278 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.721 0.278 0.000
R52.0 Acute pain
0.721 0.279 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.721 0.279 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.721 0.279 0.000
M79.6 Pain in limb
0.720 0.280 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.719 0.281 0.000
D37.0 Lip, oral cavity and pharynx
0.719 0.281 0.000
M07 Psoriatic and enteropathic arthropathies
0.718 0.281 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.718 0.282 0.000
S50-S59 Injuries to the elbow and forearm
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
J42 Unspecified chronic bronchitis
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.717 0.283 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.716 0.284 0.000
K56.2 Volvulus
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.284 0.000
T33-T35 Frostbite
0.715 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.284 0.000
S10-S19 Injuries to the neck
0.715 0.284 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.713 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.287 0.000
D47.1 Chronic myeloproliferative disease
0.713 0.287 0.000
Z29.2 Other prophylactic chemotherapy
0.713 0.287 0.000
M65 Synovitis and tenosynovitis
0.712 0.288 0.000
S20 Superficial injury of thorax
0.712 0.288 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.288 0.000
K43 Ventral hernia
0.711 0.289 0.000
F99-F99 Unspecified mental disorder
0.711 0.289 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.711 0.289 0.000
F70-F79 Mental retardation
0.711 0.289 0.000
F60-F69 Disorders of adult personality and behaviour
0.711 0.289 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.711 0.289 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.710 0.290 0.000
R30-R39 Symptoms and signs involving the urinary system
0.710 0.290 0.000
M75 Shoulder lesions
0.710 0.290 0.000
K81.9 Cholecystitis, unspecified
0.709 0.291 0.000
K86 Other diseases of pancreas
0.708 0.292 0.000
R68 Other general symptoms and signs
0.708 0.292 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.708 0.292 0.000
R62 Lack of expected normal physiological development
0.708 0.292 0.000
R64 Cachexia
0.708 0.292 0.000
R58 Haemorrhage, not elsewhere classified
0.708 0.292 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.708 0.292 0.000
C80 Malignant neoplasm without specification of site
0.707 0.293 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.705 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X60-X84 Intentional self-harm
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X20-X29 Contact with venomous animals and plants
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
B99-B99 Other infectious diseases
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.705 0.295 0.000
B65-B83 Helminthiases
0.705 0.295 0.000
B50-B64 Protozoal diseases
0.705 0.295 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.705 0.295 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.705 0.295 0.000
A80-A89 Viral infections of the central nervous system
0.705 0.295 0.000
A75-A79 Rickettsioses
0.705 0.295 0.000
A70-A74 Other diseases caused by chlamydiae
0.705 0.295 0.000
A65-A69 Other spirochaetal diseases
0.705 0.295 0.000
A20-A28 Certain zoonotic bacterial diseases
0.705 0.295 0.000
A15-A19 Tuberculosis
0.705 0.295 0.000
C32 Malignant neoplasm of larynx
0.704 0.296 0.000
M31.6 Other giant cell arteritis
0.704 0.296 0.000
G20-G26 Extrapyramidal and movement disorders
0.703 0.297 0.000
J11 Influenza, virus not identified
0.703 0.297 0.000
S70-S79 Injuries to the hip and thigh
0.703 0.297 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.703 0.297 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.703 0.297 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.703 0.297 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.703 0.297 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.703 0.297 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.703 0.297 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.703 0.297 0.000
F11 Mental and behavioural disorders due to use of opioids
0.703 0.297 0.000
J37 Chronic laryngitis and laryngotracheitis
0.703 0.297 0.000
K52 Other non-infective gastro-enteritis and colitis
0.703 0.297 0.000
R30 Pain associated with micturition
0.703 0.297 0.000
J35.0 Chronic tonsillitis
0.703 0.297 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.702 0.297 0.000
D47.2 Monoclonal gammopathy
0.702 0.298 0.000
R52.2 Other chronic pain
0.701 0.299 0.000
Y84.2 Radiological procedure and radiotherapy
0.701 0.299 0.000
N20-N23 Urolithiasis
0.701 0.299 0.000
R63.0 Anorexia
0.701 0.299 0.000
H66 Suppurative and unspecified otitis media
0.701 0.299 0.000
D37.5 Rectum
0.701 0.299 0.000
Y84.8 Other medical procedures
0.700 0.300 0.000
E73 Lactose intolerance
0.700 0.300 0.000
C77.5 Intrapelvic lymph nodes
0.700 0.300 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.699 0.301 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.699 0.301 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.699 0.301 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.699 0.301 0.000
R30.0 Dysuria
0.699 0.301 0.000
Z54 Convalescence
0.699 0.301 0.000
Z44 Fitting and adjustment of external prosthetic device
0.699 0.301 0.000
F17.9 Unspecified mental and behavioural disorder
0.698 0.301 0.000
F17.8 Other mental and behavioural disorders
0.698 0.301 0.000
F17.7 Residual and late-onset psychotic disorder
0.698 0.301 0.000
F17.6 Amnesic syndrome
0.698 0.301 0.000
F17.5 Psychotic disorder
0.698 0.301 0.000
F17.4 Withdrawal state with delirium
0.698 0.301 0.000
F17.3 Withdrawal state
0.698 0.301 0.000
F17.0 Acute intoxication
0.698 0.301 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.697 0.303 0.000
R23.4 Changes in skin texture
0.697 0.303 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.696 0.304 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.696 0.304 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.696 0.304 0.000
Z76 Persons encountering health services in other circumstances
0.695 0.305 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.695 0.305 0.000
K85.1 Biliary acute pancreatitis
0.695 0.305 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.693 0.307 0.000
J92 Pleural plaque
0.693 0.307 0.000
J18.1 Lobar pneumonia, unspecified
0.693 0.307 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.692 0.307 0.000
K36 Other appendicitis
0.692 0.308 0.000
Z52 Donors of organs and tissues
0.692 0.308 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.692 0.308 0.000
H80-H83 Diseases of inner ear
0.691 0.308 0.000
N30-N39 Other diseases of urinary system
0.691 0.309 0.000
J32.0 Chronic maxillary sinusitis
0.691 0.309 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.690 0.309 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.690 0.309 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.690 0.310 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.690 0.310 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.690 0.310 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.690 0.310 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.690 0.310 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.690 0.310 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.689 0.310 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.689 0.311 0.000
E87.3 Alkalosis
0.689 0.311 0.000
Z29.8 Other specified prophylactic measures
0.687 0.313 0.000
K62.3 Rectal prolapse
0.687 0.313 0.000
S90-S99 Injuries to the ankle and foot
0.687 0.313 0.000
Z72.9 Problem related to lifestyle, unspecified
0.687 0.313 0.000
Z72.8 Other problems related to lifestyle
0.687 0.313 0.000
Z72.6 Gambling and betting
0.687 0.313 0.000
Z72.5 High-risk sexual behaviour
0.687 0.313 0.000
Z72.4 Inappropriate diet and eating habits
0.687 0.313 0.000
Z72.3 Lack of physical exercise
0.687 0.313 0.000
Z72.2 Drug use
0.687 0.313 0.000
K56.4 Other impaction of intestine
0.687 0.313 0.000
M21 Other acquired deformities of limbs
0.687 0.313 0.000
K51.4 Pseudopolyposis of colon
0.685 0.315 0.000
J60-J70 Lung diseases due to external agents
0.685 0.315 0.000
R60 Oedema, not elsewhere classified
0.683 0.317 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.683 0.317 0.000
J35.1 Hypertrophy of tonsils
0.683 0.317 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.682 0.318 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.681 0.319 0.000
Z29.1 Prophylactic immunotherapy
0.680 0.320 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.679 0.320 0.000
M85 Other disorders of bone density and structure
0.679 0.320 0.000
K51.8 Other ulcerative colitis
0.679 0.321 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.679 0.321 0.000
Z73 Problems related to life-management difficulty
0.679 0.321 0.000
E20-E35 Disorders of other endocrine glands
0.678 0.321 0.000
M22 Disorders of patella
0.678 0.322 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.678 0.322 0.000
Y95 Nosocomial condition
0.677 0.323 0.000
R61 Hyperhidrosis
0.676 0.324 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.676 0.324 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.676 0.324 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.674 0.326 0.000
R22.2 Localised swelling, mass and lump, trunk
0.674 0.326 0.000
C34.9 Bronchus or lung, unspecified
0.674 0.326 0.000
J43.8 Other emphysema
0.673 0.326 0.000
J43.2 Centrilobular emphysema
0.673 0.326 0.000
J43.1 Panlobular emphysema
0.673 0.326 0.000
J43.0 MacLeod's syndrome
0.673 0.326 0.000
R54 Senility
0.673 0.326 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.673 0.327 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.673 0.327 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.673 0.327 0.000
N25-N29 Other disorders of kidney and ureter
0.673 0.327 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.673 0.327 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.672 0.328 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.672 0.328 0.000
H90 Conductive and sensorineural hearing loss
0.672 0.328 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.672 0.328 0.000
K62.9 Disease of anus and rectum, unspecified
0.672 0.328 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.671 0.329 0.000
D05 Carcinoma in situ of breast
0.671 0.329 0.000
N43 Hydrocele and spermatocele
0.671 0.329 0.000
K83 Other diseases of biliary tract
0.670 0.330 0.000
E50-E64 Other nutritional deficiencies
0.670 0.330 0.000
V10-V19 Pedal cyclist injured in transport accident
0.670 0.330 0.000
M71 Other bursopathies
0.670 0.330 0.000
K56.7 Ileus, unspecified
0.669 0.331 0.000
C18.7 Sigmoid colon
0.669 0.331 0.000
R94.3 Abnormal results of cardiovascular function studies
0.668 0.332 0.000
G93 Other disorders of brain
0.668 0.332 0.000
N32 Other disorders of bladder
0.667 0.333 0.000
D09 Carcinoma in situ of other and unspecified sites
0.667 0.333 0.000
E88 Other metabolic disorders
0.667 0.333 0.000
Z28 Immunisation not carried out
0.666 0.334 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.666 0.334 0.000
Z26 Need for immunisation against other single infectious diseases
0.666 0.334 0.000
Z25 Need for immunisation against other single viral diseases
0.666 0.334 0.000
Z24 Need for immunisation against certain single viral diseases
0.666 0.334 0.000
Z23 Need for immunisation against single bacterial diseases
0.666 0.334 0.000
Z20 Contact with and exposure to communicable diseases
0.666 0.334 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.666 0.334 0.000
M14 Arthropathies in other diseases classified elsewhere
0.665 0.335 0.000
M12 Other specific arthropathies
0.665 0.335 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.665 0.335 0.000
M08 Juvenile arthritis
0.665 0.335 0.000
D48.1 Connective and other soft tissue
0.665 0.335 0.000
S80-S89 Injuries to the knee and lower leg
0.665 0.335 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.665 0.335 0.000
Z22.3 Carrier of other specified bacterial diseases
0.664 0.335 0.000
Y44 Agents primarily affecting blood constituents
0.664 0.335 0.000
M76 Enthesopathies of lower limb, excluding foot
0.664 0.336 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.664 0.336 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.664 0.336 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.664 0.336 0.000
J17 Pneumonia in diseases classified elsewhere
0.664 0.336 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.664 0.336 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.664 0.336 0.000
J12 Viral pneumonia, not elsewhere classified
0.664 0.336 0.000
J10 Influenza due to identified influenza virus
0.664 0.336 0.000
J14 Pneumonia due to Haemophilus influenzae
0.664 0.336 0.000
J09 Influenza due to certain identified influenza virus
0.664 0.336 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.662 0.338 0.000
N32.8 Other specified disorders of bladder
0.661 0.339 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.660 0.340 0.000
E83 Disorders of mineral metabolism
0.660 0.340 0.000
R50.8 Other specified fever
0.660 0.340 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.660 0.340 0.000
D46 Myelodysplastic syndromes
0.659 0.340 0.000
Y59 Other and unspecified vaccines and biological substances
0.659 0.340 0.000
Y58 Bacterial vaccines
0.659 0.340 0.000
Y57 Other and unspecified drugs and medicaments
0.659 0.340 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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