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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113223489
log Bayes Factor = 11.3029
Chromosome 15   position 64,262,688  (GRCh37) Explore rs113223489 on Ensembl!
Variant rs113223489 is part of Cluster X0224

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
C18 Malignant neoplasm of colon
0.990 0.010 0.000
S60-S69 Injuries to the wrist and hand
0.989 0.011 0.000
Chapter XXI Factors influencing health status and contact with health services
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.981 0.019 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.975 0.025 0.000
C18.9 Colon, unspecified
0.974 0.026 0.000
S00-S09 Injuries to the head
0.973 0.027 0.000
Chapter X Diseases of the respiratory system
0.972 0.028 0.000
Chapter VIII Diseases of the ear and mastoid process
0.964 0.036 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.963 0.037 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.956 0.044 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.954 0.046 0.000
G90-G99 Other disorders of the nervous system
0.954 0.046 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.952 0.048 0.000
S40-S49 Injuries to the shoulder and upper arm
0.950 0.050 0.000
Z45 Adjustment and management of implanted device
0.943 0.057 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.941 0.059 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.934 0.066 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.932 0.068 0.000
Z45.2 Adjustment and management of vascular access device
0.932 0.068 0.000
C34 Malignant neoplasm of bronchus and lung
0.930 0.070 0.000
R50-R69 General symptoms and signs
0.926 0.074 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.924 0.076 0.000
S61 Open wound of wrist and hand
0.921 0.079 0.000
S01 Open wound of head
0.913 0.087 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.913 0.087 0.000
T79-T79 Certain early complications of trauma
0.911 0.089 0.000
R69 Unknown and unspecified causes of morbidity
0.911 0.089 0.000
S62 Fracture at wrist and hand level
0.905 0.095 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.904 0.096 0.000
J30-J39 Other diseases of upper respiratory tract
0.903 0.097 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.899 0.101 0.000
S64 Injury of nerves at wrist and hand level
0.898 0.102 0.000
S42 Fracture of shoulder and upper arm
0.897 0.103 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.894 0.106 0.000
E20-E35 Disorders of other endocrine glands
0.893 0.107 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.892 0.108 0.000
H90-H95 Other disorders of ear
0.889 0.111 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.889 0.111 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.888 0.112 0.000
Chapter XXII Codes for special purposes
0.888 0.112 0.000
Z04 Examination and observation for other reasons
0.887 0.113 0.000
Q60-Q64 Congenital malformations of the urinary system
0.886 0.114 0.000
S61.0 Open wound of finger(s) without damage to nail
0.878 0.122 0.000
R79 Other abnormal findings of blood chemistry
0.877 0.123 0.000
Z51 Other medical care
0.876 0.124 0.000
J30 Vasomotor and allergic rhinitis
0.870 0.130 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.870 0.130 0.000
J90-J94 Other diseases of pleura
0.868 0.132 0.000
C18.7 Sigmoid colon
0.867 0.133 0.000
Z49 Care involving dialysis
0.864 0.136 0.000
Z50 Care involving use of rehabilitation procedures
0.862 0.138 0.000
H60-H62 Diseases of external ear
0.860 0.140 0.000
Z02 Examination and encounter for administrative purposes
0.860 0.140 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.853 0.147 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.853 0.147 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.852 0.148 0.000
J09-J18 Influenza and pneumonia
0.848 0.152 0.000
M80-M85 Disorders of bone density and structure
0.847 0.153 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.847 0.153 0.000
Q61 Cystic kidney disease
0.846 0.154 0.000
R50 Fever of unknown origin
0.843 0.157 0.000
S42.4 Fracture of lower end of humerus
0.842 0.158 0.000
Z04.9 Examination and observation for unspecified reason
0.842 0.158 0.000
J30.1 Allergic rhinitis due to pollen
0.838 0.162 0.000
G90 Disorders of autonomic nervous system
0.831 0.169 0.000
C51-C58 Malignant neoplasms of female genital organs
0.831 0.169 0.000
J95-J99 Other diseases of the respiratory system
0.827 0.173 0.000
J35 Chronic diseases of tonsils and adenoids
0.825 0.175 0.000
H90 Conductive and sensorineural hearing loss
0.823 0.177 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.823 0.177 0.000
E27 Other disorders of adrenal gland
0.820 0.180 0.000
C34.3 Lower lobe, bronchus or lung
0.820 0.180 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.820 0.180 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.818 0.182 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.818 0.182 0.000
C16 Malignant neoplasm of stomach
0.817 0.183 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.816 0.184 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.814 0.186 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.811 0.189 0.000
S01.0 Open wound of scalp
0.811 0.189 0.000
Chapter I Certain infectious and parasitic diseases
0.810 0.190 0.000
J92 Pleural plaque
0.810 0.190 0.000
E10-E14 Diabetes mellitus
0.809 0.191 0.000
C34.1 Upper lobe, bronchus or lung
0.809 0.191 0.000
C85.1 B-cell lymphoma, unspecified
0.809 0.191 0.000
Z50.8 Care involving use of rehabilitation procedures
0.808 0.192 0.000
C34.9 Bronchus or lung, unspecified
0.807 0.193 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.806 0.194 0.000
R25 Abnormal involuntary movements
0.805 0.195 0.000
G93 Other disorders of brain
0.804 0.196 0.000
M81 Osteoporosis without pathological fracture
0.803 0.197 0.000
S42.40 Fracture of lower end of humerus (closed)
0.803 0.197 0.000
Z46 Fitting and adjustment of other devices
0.802 0.198 0.000
Z51.1 Chemotherapy session for neoplasm
0.801 0.199 0.000
S20-S29 Injuries to the thorax
0.800 0.200 0.000
G30-G32 Other degenerative diseases of the nervous system
0.799 0.201 0.000
S01.9 Open wound of head, part unspecified
0.799 0.201 0.000
S02 Fracture of skull and facial bones
0.798 0.202 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.798 0.202 0.000
C18.4 Transverse colon
0.798 0.202 0.000
T93 Sequelae of injuries of lower limb
0.798 0.202 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.793 0.207 0.000
Z02.8 Other examinations for administrative purposes
0.792 0.208 0.000
R59 Enlarged lymph nodes
0.791 0.209 0.000
Z43 Attention to artificial openings
0.790 0.210 0.000
Z50.1 Other physical therapy
0.789 0.211 0.000
G95 Other diseases of spinal cord
0.789 0.211 0.000
S00 Superficial injury of head
0.789 0.211 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.786 0.214 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.786 0.214 0.000
H65-H75 Diseases of middle ear and mastoid
0.786 0.214 0.000
C20 Malignant neoplasm of rectum
0.784 0.216 0.000
Z51.5 Palliative care
0.783 0.217 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.782 0.218 0.000
R50.9 Fever, unspecified
0.779 0.221 0.000
J84 Other interstitial pulmonary diseases
0.778 0.222 0.000
C18.3 Hepatic flexure
0.778 0.222 0.000
S80-S89 Injuries to the knee and lower leg
0.777 0.223 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.777 0.223 0.000
J80 Adult respiratory distress syndrome
0.776 0.224 0.000
H92 Otalgia and effusion of ear
0.776 0.224 0.000
H60 Otitis externa
0.773 0.227 0.000
T00-T07 Injuries involving multiple body regions
0.771 0.229 0.000
A30-A49 Other bacterial diseases
0.770 0.230 0.000
S62.6 Fracture of other finger
0.769 0.231 0.000
M50-M54 Other dorsopathies
0.767 0.233 0.000
S50-S59 Injuries to the elbow and forearm
0.767 0.233 0.000
D60-D64 Aplastic and other anaemias
0.766 0.234 0.000
S01.2 Open wound of nose
0.765 0.235 0.000
M81.9 Osteoporosis, unspecified
0.764 0.236 0.000
S10-S19 Injuries to the neck
0.764 0.236 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.763 0.237 0.000
Chapter XX External causes of morbidity and mortality
0.763 0.237 0.000
C25 Malignant neoplasm of pancreas
0.762 0.238 0.000
S42.1 Fracture of scapula
0.761 0.239 0.000
C91 Lymphoid leukaemia
0.760 0.240 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.757 0.243 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.757 0.243 0.000
Z49.0 Preparatory care for dialysis
0.756 0.244 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.756 0.244 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.755 0.245 0.000
Z42 Follow-up care involving plastic surgery
0.754 0.246 0.000
S40 Superficial injury of shoulder and upper arm
0.754 0.246 0.000
Chapter VII Diseases of the eye and adnexa
0.754 0.246 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.753 0.247 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.752 0.248 0.000
C18.1 Appendix
0.751 0.249 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.750 0.250 0.000
C54 Malignant neoplasm of corpus uteri
0.750 0.250 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.748 0.252 0.000
C32 Malignant neoplasm of larynx
0.748 0.252 0.000
R52 Pain, not elsewhere classified
0.747 0.253 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.747 0.253 0.000
A41 Other septicaemia
0.746 0.254 0.000
Q61.2 Polycystic kidney, adult type
0.745 0.255 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.744 0.255 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.743 0.257 0.000
S64.4 Injury of digital nerve of other finger
0.742 0.258 0.000
C83.1 Small cleaved cell (diffuse)
0.742 0.258 0.000
S62.3 Fracture of other metacarpal bone
0.741 0.259 0.000
Chapter XI Diseases of the digestive system
0.741 0.259 0.000
C18.6 Descending colon
0.740 0.260 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.740 0.260 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.740 0.260 0.000
R79.0 Abnormal level of blood mineral
0.739 0.261 0.000
T90 Sequelae of injuries of head
0.739 0.261 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.739 0.261 0.000
J92.9 Pleural plaque without asbestos
0.739 0.261 0.000
R26 Abnormalities of gait and mobility
0.738 0.262 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.737 0.263 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.736 0.264 0.000
R71 Abnormality of red blood cells
0.735 0.265 0.000
Z45.1 Adjustment and management of infusion pump
0.734 0.266 0.000
J33 Nasal polyp
0.734 0.266 0.000
G91 Hydrocephalus
0.733 0.267 0.000
Z51.3 Blood transfusion without reported diagnosis
0.733 0.267 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.732 0.268 0.000
J90 Pleural effusion, not elsewhere classified
0.731 0.269 0.000
Q61.0 Congenital single renal cyst
0.730 0.270 0.000
D69 Purpura and other haemorrhagic conditions
0.730 0.270 0.000
S05 Injury of eye and orbit
0.730 0.270 0.000
S68 Traumatic amputation of wrist and hand
0.730 0.270 0.000
J35.0 Chronic tonsillitis
0.729 0.271 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.729 0.271 0.000
S42.2 Fracture of upper end of humerus
0.729 0.271 0.000
R27 Other lack of coordination
0.729 0.271 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.729 0.271 0.000
H72 Perforation of tympanic membrane
0.728 0.272 0.000
E50-E64 Other nutritional deficiencies
0.728 0.272 0.000
T91 Sequelae of injuries of neck and trunk
0.726 0.274 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.725 0.275 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.725 0.275 0.000
R25.2 Cramp and spasm
0.724 0.276 0.000
Z40 Prophylactic surgery
0.723 0.277 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.722 0.278 0.000
Z00.0 General medical examination
0.721 0.279 0.000
G70-G73 Diseases of myoneural junction and muscle
0.721 0.279 0.000
D68 Other coagulation defects
0.720 0.280 0.000
M54 Dorsalgia
0.720 0.280 0.000
K70-K77 Diseases of liver
0.720 0.280 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.720 0.280 0.000
R63 Symptoms and signs concerning food and fluid intake
0.720 0.280 0.000
K50-K52 Noninfective enteritis and colitis
0.718 0.282 0.000
S09 Other and unspecified injuries of head
0.717 0.283 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.717 0.283 0.000
E23 Hypofunction and other disorders of pituitary gland
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
J60-J70 Lung diseases due to external agents
0.717 0.283 0.000
M05-M14 Inflammatory polyarthropathies
0.717 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.716 0.284 0.000
C21 Malignant neoplasm of anus and anal canal
0.716 0.284 0.000
C17 Malignant neoplasm of small intestine
0.716 0.284 0.000
C23 Malignant neoplasm of gallbladder
0.716 0.284 0.000
C92 Myeloid leukaemia
0.714 0.286 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.714 0.286 0.000
T92 Sequelae of injuries of upper limb
0.714 0.286 0.000
H90.2 Conductive hearing loss, unspecified
0.712 0.288 0.000
E70-E90 Metabolic disorders
0.711 0.289 0.000
J36 Peritonsillar abscess
0.711 0.289 0.000
C18.8 Overlapping lesion of colon
0.710 0.290 0.000
S06 Intracranial injury
0.710 0.290 0.000
S65 Injury of blood vessels at wrist and hand level
0.709 0.291 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.708 0.292 0.000
Q61.3 Polycystic kidney, unspecified
0.708 0.292 0.000
J98 Other respiratory disorders
0.708 0.292 0.000
W00-W19 Falls
0.707 0.293 0.000
H90.5 Sensorineural hearing loss, unspecified
0.707 0.293 0.000
H60.9 Otitis externa, unspecified
0.706 0.294 0.000
E27.1 Primary adrenocortical insufficiency
0.706 0.294 0.000
E22 Hyperfunction of pituitary gland
0.706 0.294 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.705 0.295 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.703 0.296 0.000
C95 Leukaemia of unspecified cell type
0.703 0.296 0.000
C94 Other leukaemias of specified cell type
0.703 0.296 0.000
C93 Monocytic leukaemia
0.703 0.296 0.000
C88 Malignant immunoproliferative diseases
0.703 0.296 0.000
C86 Other specified types of T/NK-cell lymphoma
0.703 0.296 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.703 0.296 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.703 0.297 0.000
S80 Superficial injury of lower leg
0.701 0.298 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.701 0.299 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.701 0.299 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.701 0.299 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.701 0.299 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.700 0.300 0.000
G96 Other disorders of central nervous system
0.700 0.300 0.000
J14 Pneumonia due to Haemophilus influenzae
0.700 0.300 0.000
A41.9 Septicaemia, unspecified
0.699 0.301 0.000
Z44 Fitting and adjustment of external prosthetic device
0.699 0.301 0.000
S70-S79 Injuries to the hip and thigh
0.698 0.302 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.698 0.302 0.000
S08 Traumatic amputation of part of head
0.697 0.303 0.000
S07 Crushing injury of head
0.697 0.303 0.000
S04 Injury of cranial nerves
0.697 0.303 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.697 0.303 0.000
R73 Elevated blood glucose level
0.697 0.303 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.696 0.304 0.000
Z46.6 Fitting and adjustment of urinary device
0.695 0.305 0.000
C80 Malignant neoplasm without specification of site
0.695 0.305 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.695 0.305 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.694 0.306 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.692 0.308 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.692 0.308 0.000
C54.1 Endometrium
0.692 0.308 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.691 0.309 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.691 0.309 0.000
S69 Other and unspecified injuries of wrist and hand
0.691 0.309 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.691 0.309 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.691 0.309 0.000
C31 Malignant neoplasm of accessory sinuses
0.691 0.309 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.691 0.309 0.000
C37 Malignant neoplasm of thymus
0.691 0.309 0.000
C33 Malignant neoplasm of trachea
0.691 0.309 0.000
T86 Failure and rejection of transplanted organs and tissues
0.690 0.310 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.689 0.311 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.689 0.311 0.000
S61.1 Open wound of finger(s) with damage to nail
0.689 0.311 0.000
Q50-Q56 Congenital malformations of genital organs
0.688 0.312 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.688 0.312 0.000
M65-M68 Disorders of synovium and tendon
0.687 0.313 0.000
S67 Crushing injury of wrist and hand
0.686 0.314 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.686 0.314 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.686 0.314 0.000
D00-D09 In situ neoplasms
0.686 0.314 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.685 0.314 0.000
C85.0 Lymphosarcoma
0.685 0.314 0.000
Z10 Routine general health check-up of defined subpopulation
0.684 0.316 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.684 0.316 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
G92 Toxic encephalopathy
0.684 0.316 0.000
R58 Haemorrhage, not elsewhere classified
0.684 0.316 0.000
R54 Senility
0.683 0.316 0.000
J30.4 Allergic rhinitis, unspecified
0.683 0.317 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.683 0.317 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.682 0.318 0.000
E11 Non-insulin-dependent diabetes mellitus
0.682 0.318 0.000
Z49.2 Other dialysis
0.682 0.318 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.682 0.318 0.000
S48 Traumatic amputation of shoulder and upper arm
0.681 0.319 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.681 0.319 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.681 0.319 0.000
S44 Injury of nerves at shoulder and upper arm level
0.681 0.319 0.000
S41 Open wound of shoulder and upper arm
0.681 0.319 0.000
S47 Crushing injury of shoulder and upper arm
0.681 0.319 0.000
E34 Other endocrine disorders
0.681 0.319 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.681 0.319 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.680 0.319 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.680 0.320 0.000
S62.5 Fracture of thumb
0.680 0.320 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.680 0.320 0.000
G90.3 Multisystem degeneration
0.679 0.321 0.000
T79.6 Traumatic ischaemia of muscle
0.679 0.321 0.000
C16.2 Body of stomach
0.678 0.322 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.678 0.322 0.000
Q00-Q07 Congenital malformations of the nervous system
0.677 0.323 0.000
Z54 Convalescence
0.677 0.323 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.676 0.324 0.000
Z45.3 Adjustment and management of implanted hearing device
0.676 0.324 0.000
T66-T78 Other and unspecified effects of external causes
0.676 0.324 0.000
Z52 Donors of organs and tissues
0.675 0.325 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.675 0.325 0.000
Q80-Q89 Other congenital malformations
0.675 0.325 0.000
Q35-Q37 Cleft lip and cleft palate
0.675 0.325 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.675 0.325 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.675 0.325 0.000
R59.1 Generalised enlarged lymph nodes
0.674 0.326 0.000
J92.0 Pleural plaque with presence of asbestos
0.674 0.326 0.000
G95.8 Other specified diseases of spinal cord
0.674 0.326 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.673 0.326 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
S64.3 Injury of digital nerve of thumb
0.672 0.328 0.000
T93.2 Sequelae of other fractures of lower limb
0.672 0.328 0.000
S60 Superficial injury of wrist and hand
0.672 0.328 0.000
J98.1 Pulmonary collapse
0.671 0.329 0.000
S62.60 Fracture of other finger (closed)
0.670 0.330 0.000
K50 Crohn's disease [regional enteritis]
0.670 0.330 0.000
C18.5 Splenic flexure
0.669 0.331 0.000
J81 Pulmonary oedema
0.669 0.331 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.669 0.331 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.669 0.331 0.000
R80 Isolated proteinuria
0.669 0.331 0.000
W19 Unspecified fall
0.669 0.331 0.000
D55-D59 Haemolytic anaemias
0.668 0.332 0.000
A41.8 Other specified septicaemia
0.668 0.332 0.000
R50.0 Fever with chills
0.668 0.332 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.668 0.332 0.000
C34.8 Overlapping lesion of bronchus and lung
0.667 0.333 0.000
C34.2 Middle lobe, bronchus or lung
0.667 0.333 0.000
C34.0 Main bronchus
0.667 0.333 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.667 0.333 0.000
K76 Other diseases of liver
0.667 0.333 0.000
M80 Osteoporosis with pathological fracture
0.666 0.334 0.000
S00.1 Contusion of eyelid and periocular area
0.666 0.334 0.000
S61.8 Open wound of other parts of wrist and hand
0.666 0.334 0.000
R61 Hyperhidrosis
0.665 0.335 0.000
M91-M94 Chondropathies
0.665 0.335 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.664 0.336 0.000
R62 Lack of expected normal physiological development
0.664 0.336 0.000
R64 Cachexia
0.664 0.336 0.000
Z43.8 Attention to other artificial openings
0.664 0.336 0.000
M81.98 Osteoporosis, unspecified (Other)
0.664 0.336 0.000
K52 Other non-infective gastro-enteritis and colitis
0.663 0.337 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.663 0.337 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.663 0.337 0.000
S42.10 Fracture of scapula (closed)
0.663 0.337 0.000
T98 Sequelae of other and unspecified effects of external causes
0.662 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.662 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.662 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.662 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.662 0.337 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.661 0.339 0.000
H92.1 Otorrhoea
0.661 0.339 0.000
G58 Other mononeuropathies
0.661 0.339 0.000
S61.7 Multiple open wounds of wrist and hand
0.660 0.339 0.000
R52.2 Other chronic pain
0.660 0.340 0.000
C16.0 Cardia
0.659 0.341 0.000
J11 Influenza, virus not identified
0.658 0.342 0.000
J33.9 Nasal polyp, unspecified
0.656 0.344 0.000
Z51.9 Medical care, unspecified
0.656 0.344 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.655 0.345 0.000
R57 Shock, not elsewhere classified
0.655 0.345 0.000
C26.0 Intestinal tract, part unspecified
0.655 0.345 0.000
S01.7 Multiple open wounds of head
0.655 0.345 0.000
S01.4 Open wound of cheek and temporomandibular area
0.655 0.345 0.000
W19.9 Unspecified place
0.655 0.345 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.654 0.346 0.000
R77 Other abnormalities of plasma proteins
0.654 0.346 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.654 0.346 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.654 0.346 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.654 0.346 0.000
C15 Malignant neoplasm of oesophagus
0.654 0.346 0.000
D72 Other disorders of white blood cells
0.654 0.346 0.000
Z74 Problems related to care-provider dependency
0.653 0.347 0.000
H61 Other disorders of external ear
0.652 0.348 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.651 0.349 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.651 0.349 0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.650 0.350 0.000
S62.2 Fracture of first metacarpal bone
0.650 0.350 0.000
G61 Inflammatory polyneuropathy
0.649 0.351 0.000
S62.7 Multiple fractures of fingers
0.649 0.351 0.000
S62.4 Multiple fractures of metacarpal bones
0.649 0.351 0.000
S62.1 Fracture of other carpal bone(s)
0.649 0.351 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.649 0.351 0.000
H53-H54 Visual disturbances and blindness
0.649 0.351 0.000
J37 Chronic laryngitis and laryngotracheitis
0.648 0.352 0.000
H30-H36 Disorders of choroid and retina
0.647 0.352 0.000
E27.8 Other specified disorders of adrenal gland
0.647 0.353 0.000
M20-M25 Other joint disorders
0.647 0.353 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.645 0.355 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.645 0.355 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.644 0.356 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.644 0.356 0.000
S00.5 Superficial injury of lip and oral cavity
0.644 0.356 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.644 0.356 0.000
S64.8 Injury of other nerves at wrist and hand level
0.644 0.356 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.644 0.356 0.000
S64.1 Injury of median nerve at wrist and hand level
0.644 0.356 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.643 0.357 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.643 0.357 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.643 0.357 0.000
C83.0 Small cell (diffuse)
0.643 0.357 0.000
Z04.8 Examination and observation for other specified reasons
0.643 0.357 0.000
G95.1 Vascular myelopathies
0.642 0.358 0.000
C81 Hodgkin's disease
0.642 0.358 0.000
H93 Other disorders of ear, not elsewhere classified
0.641 0.358 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.641 0.359 0.000
M40-M43 Deforming dorsopathies
0.641 0.359 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.641 0.359 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.640 0.360 0.000
E32 Diseases of thymus
0.640 0.360 0.000
E31 Polyglandular dysfunction
0.640 0.360 0.000
E30 Disorders of puberty, not elsewhere classified
0.640 0.360 0.000
E29 Testicular dysfunction
0.640 0.360 0.000
E26 Hyperaldosteronism
0.640 0.360 0.000
E25 Adrenogenital disorders
0.640 0.360 0.000
E24 Cushing's syndrome
0.640 0.360 0.000
E20 Hypoparathyroidism
0.640 0.360 0.000
M60-M63 Disorders of muscles
0.640 0.360 0.000
M00-M03 Infectious arthropathies
0.640 0.360 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.639 0.361 0.000
R74 Abnormal serum enzyme levels
0.638 0.361 0.000
G51 Facial nerve disorders
0.638 0.362 0.000
R59.0 Localised enlarged lymph nodes
0.637 0.363 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.637 0.363 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.637 0.363 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.637 0.363 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.637 0.363 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.637 0.363 0.000
D61 Other aplastic anaemias
0.636 0.363 0.000
Z04.6 General psychiatric examination, requested by authority
0.636 0.364 0.000
Z04.5 Examination and observation following other inflicted injury
0.636 0.364 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.636 0.364 0.000
Z04.2 Examination and observation following work accident
0.636 0.364 0.000
Z04.1 Examination and observation following transport accident
0.636 0.364 0.000
Z04.0 Blood-alcohol and blood-drug test
0.636 0.364 0.000
Q63 Other congenital malformations of kidney
0.635 0.365 0.000
Q64 Other congenital malformations of urinary system
0.635 0.365 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.635 0.365 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.635 0.365 0.000
J10 Influenza due to identified influenza virus
0.634 0.366 0.000
M54.9 Dorsalgia, unspecified
0.634 0.366 0.000
M54.1 Radiculopathy
0.633 0.367 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.633 0.367 0.000
E83 Disorders of mineral metabolism
0.632 0.368 0.000
S90-S99 Injuries to the ankle and foot
0.632 0.368 0.000
L03 Cellulitis
0.632 0.368 0.000
C18.2 Ascending colon
0.631 0.369 0.000
R81 Glycosuria
0.631 0.369 0.000
J35.1 Hypertrophy of tonsils
0.630 0.370 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.629 0.371 0.000
D45 Polycythaemia vera
0.629 0.371 0.000
Z43.2 Attention to ileostomy
0.629 0.371 0.000
M13 Other arthritis
0.629 0.371 0.000
H90.3 Sensorineural hearing loss, bilateral
0.629 0.371 0.000
T87 Complications peculiar to reattachment and amputation
0.628 0.371 0.000
S32 Fracture of lumbar spine and pelvis
0.628 0.372 0.000
Z51.6 Desensitisation to allergens
0.628 0.372 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.628 0.372 0.000
M84 Disorders of continuity of bone
0.627 0.373 0.000
E11.3 With ophthalmic complications
0.627 0.373 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.627 0.373 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.627 0.373 0.000
E10 Insulin-dependent diabetes mellitus
0.627 0.373 0.000
J94 Other pleural conditions
0.626 0.374 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.625 0.375 0.000
R25.3 Fasciculation
0.625 0.375 0.000
R82 Other abnormal findings in urine
0.625 0.375 0.000
S01.3 Open wound of ear
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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