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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114892859
log Bayes Factor = 25.3426
Chromosome 6   position 31,369,278  (GRCh37) Explore rs114892859 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z88.0 Personal history of allergy to penicillin
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.993 0.007 0.000
N60-N64 Disorders of breast
0.986 0.014 0.000
Chapter VII Diseases of the eye and adnexa
0.982 0.018 0.000
F30-F39 Mood [affective] disorders
0.980 0.020 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
Chapter I Certain infectious and parasitic diseases
0.975 0.025 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
M05-M14 Inflammatory polyarthropathies
0.963 0.037 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.962 0.038 0.000
N20-N23 Urolithiasis
0.960 0.040 0.000
F31 Bipolar affective disorder
0.950 0.050 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.948 0.052 0.000
S00-S09 Injuries to the head
0.938 0.062 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.938 0.062 0.000
Chapter II Neoplasms
0.937 0.063 0.000
H53-H54 Visual disturbances and blindness
0.932 0.068 0.000
F41 Other anxiety disorders
0.929 0.071 0.000
N64 Other disorders of breast
0.927 0.073 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.923 0.077 0.000
N20 Calculus of kidney and ureter
0.919 0.081 0.000
S80-S89 Injuries to the knee and lower leg
0.914 0.086 0.000
F41.2 Mixed anxiety and depressive disorder
0.914 0.086 0.000
Chapter X Diseases of the respiratory system
0.910 0.090 0.000
N10-N16 Renal tubulo-interstitial diseases
0.905 0.095 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.903 0.097 0.000
M50-M54 Other dorsopathies
0.893 0.107 0.000
H10-H13 Disorders of conjunctiva
0.890 0.110 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.888 0.112 0.000
Chapter IX Diseases of the circulatory system
0.884 0.116 0.000
F33 Recurrent depressive disorder
0.883 0.117 0.000
H55-H59 Other disorders of eye and adnexa
0.878 0.122 0.000
M05 Seropositive rheumatoid arthritis
0.877 0.123 0.000
F31.9 Bipolar affective disorder, unspecified
0.873 0.127 0.000
N60 Benign mammary dysplasia
0.872 0.128 0.000
B25-B34 Other viral diseases
0.869 0.131 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.868 0.132 0.000
N20.1 Calculus of ureter
0.864 0.136 0.000
C44 Other malignant neoplasms of skin
0.862 0.138 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.861 0.139 0.000
C44.3 Skin of other and unspecified parts of face
0.860 0.140 0.000
F03 Unspecified dementia
0.859 0.141 0.000
N64.1 Fat necrosis of breast
0.848 0.152 0.000
B15-B19 Viral hepatitis
0.847 0.153 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.843 0.157 0.000
M50 Cervical disk disorders
0.842 0.158 0.000
H54 Blindness and low vision
0.842 0.158 0.000
N61 Inflammatory disorders of breast
0.842 0.158 0.000
M13 Other arthritis
0.841 0.159 0.000
N23 Unspecified renal colic
0.840 0.160 0.000
J95-J99 Other diseases of the respiratory system
0.837 0.163 0.000
A30-A49 Other bacterial diseases
0.836 0.164 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.834 0.166 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.832 0.168 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.830 0.170 0.000
H53 Visual disturbances
0.825 0.175 0.000
T66-T78 Other and unspecified effects of external causes
0.825 0.175 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.822 0.178 0.000
S01 Open wound of head
0.820 0.180 0.000
T79-T79 Certain early complications of trauma
0.818 0.182 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.817 0.183 0.000
N20.0 Calculus of kidney
0.817 0.183 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.815 0.185 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.815 0.185 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.813 0.187 0.000
M06 Other rheumatoid arthritis
0.811 0.189 0.000
N63 Unspecified lump in breast
0.811 0.189 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.808 0.192 0.000
F34 Persistent mood [affective] disorders
0.807 0.193 0.000
H57 Other disorders of eye and adnexa
0.804 0.196 0.000
N10 Acute tubulo-interstitial nephritis
0.804 0.196 0.000
M07 Psoriatic and enteropathic arthropathies
0.803 0.197 0.000
W20-W49 Exposure to inanimate mechanical forces
0.801 0.199 0.000
I30-I52 Other forms of heart disease
0.799 0.201 0.000
W00-W19 Falls
0.799 0.201 0.000
C60-C63 Malignant neoplasms of male genital organs
0.798 0.202 0.000
Chapter VI Diseases of the nervous system
0.796 0.204 0.000
J09-J18 Influenza and pneumonia
0.796 0.204 0.000
N25-N29 Other disorders of kidney and ureter
0.795 0.205 0.000
N62 Hypertrophy of breast
0.794 0.206 0.000
S60-S69 Injuries to the wrist and hand
0.793 0.207 0.000
F80-F89 Disorders of psychological development
0.789 0.211 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.788 0.212 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.784 0.216 0.000
N75 Diseases of Bartholin's gland
0.783 0.217 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.782 0.218 0.000
H11 Other disorders of conjunctiva
0.782 0.218 0.000
S50-S59 Injuries to the elbow and forearm
0.781 0.219 0.000
F40 Phobic anxiety disorders
0.778 0.222 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.778 0.222 0.000
J98 Other respiratory disorders
0.777 0.223 0.000
Q60-Q64 Congenital malformations of the urinary system
0.777 0.223 0.000
S82 Fracture of lower leg, including ankle
0.777 0.223 0.000
S70-S79 Injuries to the hip and thigh
0.776 0.224 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.776 0.224 0.000
M80-M85 Disorders of bone density and structure
0.775 0.225 0.000
C73 Malignant neoplasm of thyroid gland
0.775 0.225 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.774 0.226 0.000
S06 Intracranial injury
0.773 0.227 0.000
B34 Viral infection of unspecified site
0.773 0.227 0.000
I51 Complications and ill-defined descriptions of heart disease
0.772 0.228 0.000
M50.2 Other cervical disk displacement
0.769 0.231 0.000
N64.5 Other signs and symptoms in breast
0.769 0.231 0.000
A00-A09 Intestinal infectious diseases
0.769 0.231 0.000
F33.9 Recurrent depressive disorder, unspecified
0.769 0.231 0.000
X20-X29 Contact with venomous animals and plants
0.768 0.232 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.766 0.234 0.000
I26 Pulmonary embolism
0.766 0.234 0.000
S00 Superficial injury of head
0.766 0.234 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.764 0.236 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.764 0.236 0.000
M91-M94 Chondropathies
0.762 0.238 0.000
N13 Obstructive and reflux uropathy
0.761 0.239 0.000
N60.1 Diffuse cystic mastopathy
0.758 0.241 0.000
D00-D09 In situ neoplasms
0.756 0.244 0.000
Q50-Q56 Congenital malformations of genital organs
0.756 0.244 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.756 0.244 0.000
M00-M03 Infectious arthropathies
0.755 0.244 0.000
H54.7 Unspecified visual loss
0.755 0.245 0.000
M14 Arthropathies in other diseases classified elsewhere
0.755 0.245 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.754 0.246 0.000
A49 Bacterial infection of unspecified site
0.754 0.246 0.000
M13.9 Arthritis, unspecified
0.753 0.247 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.752 0.248 0.000
S20-S29 Injuries to the thorax
0.748 0.252 0.000
J98.1 Pulmonary collapse
0.747 0.253 0.000
C44.4 Skin of scalp and neck
0.747 0.253 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.745 0.255 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.744 0.255 0.000
J60-J70 Lung diseases due to external agents
0.744 0.256 0.000
A80-A89 Viral infections of the central nervous system
0.744 0.256 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.743 0.257 0.000
Y52 Agents primarily affecting the cardiovascular system
0.743 0.257 0.000
B95-B98 Bacterial, viral and other infectious agents
0.742 0.258 0.000
S40-S49 Injuries to the shoulder and upper arm
0.741 0.259 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.739 0.261 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.737 0.263 0.000
Chapter VIII Diseases of the ear and mastoid process
0.736 0.264 0.000
H10 Conjunctivitis
0.735 0.265 0.000
N60.3 Fibrosclerosis of breast
0.733 0.266 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.732 0.268 0.000
Chapter XXII Codes for special purposes
0.731 0.268 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.731 0.269 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.731 0.269 0.000
F43 Reaction to severe stress, and adjustment disorders
0.730 0.270 0.000
I51.8 Other ill-defined heart diseases
0.729 0.271 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.729 0.271 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.724 0.276 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.723 0.277 0.000
H57.1 Ocular pain
0.723 0.277 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.722 0.278 0.000
B18 Chronic viral hepatitis
0.721 0.279 0.000
F00 Dementia in Alzheimer's disease
0.721 0.279 0.000
I85 Oesophageal varices
0.721 0.279 0.000
I81 Portal vein thrombosis
0.720 0.279 0.000
H43-H45 Disorders of vitreous body and globe
0.720 0.280 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.719 0.281 0.000
F06.7 Mild cognitive disorder
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.283 0.000
F70-F79 Mental retardation
0.716 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
M65-M68 Disorders of synovium and tendon
0.716 0.284 0.000
N20.9 Urinary calculus, unspecified
0.715 0.285 0.000
S01.5 Open wound of lip and oral cavity
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.714 0.286 0.000
N64.9 Disorder of breast, unspecified
0.714 0.286 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.714 0.286 0.000
S05 Injury of eye and orbit
0.713 0.286 0.000
I51.7 Cardiomegaly
0.712 0.288 0.000
H54.0 Blindness, both eyes
0.712 0.288 0.000
T63 Toxic effect of contact with venomous animals
0.710 0.290 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.710 0.290 0.000
S80 Superficial injury of lower leg
0.710 0.290 0.000
H53.0 Amblyopia ex anopsia
0.709 0.291 0.000
I80 Phlebitis and thrombophlebitis
0.708 0.292 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.707 0.293 0.000
S90-S99 Injuries to the ankle and foot
0.706 0.293 0.000
T39.0 Salicylates
0.706 0.294 0.000
C51-C58 Malignant neoplasms of female genital organs
0.706 0.294 0.000
B34.9 Viral infection, unspecified
0.705 0.295 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.704 0.296 0.000
F38 Other mood [affective] disorders
0.703 0.297 0.000
F30 Manic episode
0.703 0.297 0.000
F39 Unspecified mood [affective] disorder
0.703 0.297 0.000
M60-M63 Disorders of muscles
0.702 0.297 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.701 0.299 0.000
T78 Adverse effects, not elsewhere classified
0.701 0.299 0.000
A49.0 Staphylococcal infection, unspecified
0.701 0.299 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.700 0.300 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.700 0.300 0.000
G90-G99 Other disorders of the nervous system
0.699 0.301 0.000
B99-B99 Other infectious diseases
0.699 0.301 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.699 0.301 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.699 0.301 0.000
B65-B83 Helminthiases
0.699 0.301 0.000
B50-B64 Protozoal diseases
0.699 0.301 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.699 0.301 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.699 0.301 0.000
A75-A79 Rickettsioses
0.699 0.301 0.000
A70-A74 Other diseases caused by chlamydiae
0.699 0.301 0.000
A65-A69 Other spirochaetal diseases
0.699 0.301 0.000
A20-A28 Certain zoonotic bacterial diseases
0.699 0.301 0.000
A15-A19 Tuberculosis
0.699 0.301 0.000
Q21 Congenital malformations of cardiac septa
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V80-V89 Other land transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V10-V19 Pedal cyclist injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
C61 Malignant neoplasm of prostate
0.699 0.301 0.000
M06.9 Rheumatoid arthritis, unspecified
0.699 0.301 0.000
Y40 Systemic antibiotics
0.698 0.302 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.698 0.302 0.000
X60-X84 Intentional self-harm
0.696 0.304 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.696 0.304 0.000
F99-F99 Unspecified mental disorder
0.696 0.304 0.000
J11 Influenza, virus not identified
0.695 0.305 0.000
S02 Fracture of skull and facial bones
0.695 0.305 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.695 0.305 0.000
G20-G26 Extrapyramidal and movement disorders
0.691 0.309 0.000
M50.3 Other cervical disk degeneration
0.691 0.309 0.000
M12 Other specific arthropathies
0.690 0.309 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.690 0.309 0.000
M08 Juvenile arthritis
0.690 0.309 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.690 0.310 0.000
F48 Other neurotic disorders
0.690 0.310 0.000
F44 Dissociative [conversion] disorders
0.690 0.310 0.000
F42 Obsessive-compulsive disorder
0.690 0.310 0.000
F41.1 Generalised anxiety disorder
0.689 0.311 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.689 0.311 0.000
M07.3 Other psoriatic arthropathies
0.688 0.312 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.688 0.312 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.687 0.313 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.686 0.313 0.000
S01.9 Open wound of head, part unspecified
0.686 0.314 0.000
M70-M79 Other soft tissue disorders
0.686 0.314 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.686 0.314 0.000
M20-M25 Other joint disorders
0.685 0.315 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.685 0.315 0.000
F34.1 Dysthymia
0.683 0.317 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.683 0.317 0.000
D45 Polycythaemia vera
0.682 0.317 0.000
N75.1 Abscess of Bartholin's gland
0.682 0.318 0.000
F31.8 Other bipolar affective disorders
0.681 0.319 0.000
F31.7 Bipolar affective disorder, currently in remission
0.681 0.319 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.681 0.319 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.681 0.319 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.681 0.319 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.681 0.319 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.680 0.320 0.000
F02 Dementia in other diseases classified elsewhere
0.680 0.320 0.000
F01 Vascular dementia
0.680 0.320 0.000
F09 Unspecified organic or symptomatic mental disorder
0.680 0.320 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.680 0.320 0.000
N99-N99 Other disorders of the genitourinary system
0.679 0.321 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.678 0.322 0.000
N71 Inflammatory disease of uterus, except cervix
0.677 0.323 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.677 0.323 0.000
Q23 Congenital malformations of aortic and mitral valves
0.676 0.324 0.000
S01.2 Open wound of nose
0.675 0.325 0.000
D47.2 Monoclonal gammopathy
0.675 0.325 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.674 0.326 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.673 0.327 0.000
D06 Carcinoma in situ of cervix uteri
0.673 0.327 0.000
S08 Traumatic amputation of part of head
0.673 0.327 0.000
S07 Crushing injury of head
0.673 0.327 0.000
S04 Injury of cranial nerves
0.673 0.327 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.673 0.327 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.673 0.327 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.673 0.327 0.000
Q80-Q89 Other congenital malformations
0.673 0.327 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.673 0.327 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.673 0.327 0.000
Q35-Q37 Cleft lip and cleft palate
0.673 0.327 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.673 0.327 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.673 0.327 0.000
Q00-Q07 Congenital malformations of the nervous system
0.673 0.327 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.673 0.327 0.000
B17 Other acute viral hepatitis
0.672 0.327 0.000
B25 Cytomegaloviral disease
0.672 0.328 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.672 0.328 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.672 0.328 0.000
H50 Other strabismus
0.671 0.329 0.000
F41.8 Other specified anxiety disorders
0.666 0.334 0.000
F41.3 Other mixed anxiety disorders
0.666 0.334 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.666 0.334 0.000
N64.4 Mastodynia
0.664 0.335 0.000
N64.3 Galactorrhoea not associated with childbirth
0.664 0.335 0.000
N64.2 Atrophy of breast
0.664 0.335 0.000
N64.0 Fissure and fistula of nipple
0.664 0.335 0.000
M53 Other dorsopathies, not elsewhere classified
0.664 0.336 0.000
M10 Gout
0.664 0.336 0.000
T39.1 4-Aminophenol derivatives
0.663 0.337 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.662 0.338 0.000
J10 Influenza due to identified influenza virus
0.662 0.338 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.661 0.338 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.338 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.661 0.338 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.661 0.338 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.661 0.338 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.661 0.338 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.338 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.661 0.338 0.000
T36 Poisoning by systemic antibiotics
0.661 0.338 0.000
M50.1 Cervical disk disorder with radiculopathy
0.659 0.341 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.659 0.341 0.000
W22 Striking against or struck by other objects
0.657 0.343 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.657 0.343 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.657 0.343 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.656 0.344 0.000
S88 Traumatic amputation of lower leg
0.655 0.345 0.000
S87 Crushing injury of lower leg
0.655 0.345 0.000
S86 Injury of muscle and tendon at lower leg level
0.655 0.345 0.000
S85 Injury of blood vessels at lower leg level
0.655 0.345 0.000
S84 Injury of nerves at lower leg level
0.655 0.345 0.000
N76 Other inflammation of vagina and vulva
0.654 0.345 0.000
M11 Other crystal arthropathies
0.654 0.346 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.654 0.346 0.000
Y57 Other and unspecified drugs and medicaments
0.654 0.346 0.000
N60.2 Fibroadenosis of breast
0.653 0.347 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.652 0.347 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.652 0.348 0.000
M86-M90 Other osteopathies
0.652 0.348 0.000
Y44 Agents primarily affecting blood constituents
0.651 0.348 0.000
N75.0 Cyst of Bartholin's gland
0.651 0.349 0.000
Y85 Sequelae of transport accidents
0.650 0.350 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.649 0.351 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.649 0.351 0.000
N15 Other renal tubulo-interstitial diseases
0.649 0.351 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.649 0.351 0.000
N11 Chronic tubulo-interstitial nephritis
0.649 0.351 0.000
M85 Other disorders of bone density and structure
0.649 0.351 0.000
M24 Other specific joint derangements
0.649 0.351 0.000
Y59 Other and unspecified vaccines and biological substances
0.647 0.353 0.000
Y58 Bacterial vaccines
0.647 0.353 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.647 0.353 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.647 0.353 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.647 0.353 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.647 0.353 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.647 0.353 0.000
Y48 Anaesthetics and therapeutic gases
0.647 0.353 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.647 0.353 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.647 0.353 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.647 0.353 0.000
T90 Sequelae of injuries of head
0.647 0.353 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.647 0.353 0.000
H53.2 Diplopia
0.646 0.354 0.000
I42 Cardiomyopathy
0.646 0.354 0.000
F40.2 Specific (isolated) phobias
0.645 0.355 0.000
J00-J06 Acute upper respiratory infections
0.645 0.355 0.000
C64-C68 Malignant neoplasms of urinary tract
0.644 0.356 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.643 0.357 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.643 0.357 0.000
S00.9 Superficial injury of head, part unspecified
0.643 0.357 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.643 0.357 0.000
S89 Other and unspecified injuries of lower leg
0.641 0.359 0.000
M13.98 Arthritis, unspecified (Other)
0.640 0.360 0.000
B35-B49 Mycoses
0.640 0.360 0.000
N64.8 Other specified disorders of breast
0.639 0.360 0.000
F81 Specific developmental disorders of scholastic skills
0.638 0.362 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.638 0.362 0.000
S82.2 Fracture of shaft of tibia
0.637 0.363 0.000
T40.2 Other opioids
0.636 0.364 0.000
J69 Pneumonitis due to solids and liquids
0.635 0.365 0.000
S82.8 Fractures of other parts of lower leg
0.635 0.365 0.000
I00-I02 Acute rheumatic fever
0.634 0.366 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.634 0.366 0.000
F22 Persistent delusional disorders
0.634 0.366 0.000
S00.8 Superficial injury of other parts of head
0.634 0.366 0.000
M51 Other intervertebral disk disorders
0.633 0.367 0.000
F33.8 Other recurrent depressive disorders
0.633 0.367 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.633 0.367 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.633 0.367 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.633 0.367 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.633 0.367 0.000
Y95 Nosocomial condition
0.633 0.367 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.633 0.367 0.000
I85.9 Oesophageal varices without bleeding
0.632 0.368 0.000
H49 Paralytic strabismus
0.632 0.368 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.632 0.368 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.631 0.369 0.000
B18.2 Chronic viral hepatitis C
0.631 0.369 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.631 0.369 0.000
I82 Other venous embolism and thrombosis
0.630 0.370 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.630 0.370 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.630 0.370 0.000
H55 Nystagmus and other irregular eye movements
0.630 0.370 0.000
A08 Viral and other specified intestinal infections
0.629 0.371 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.629 0.371 0.000
N60.8 Other benign mammary dysplasias
0.629 0.371 0.000
M05.8 Other seropositive rheumatoid arthritis
0.629 0.371 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.629 0.371 0.000
M05.2 Rheumatoid vasculitis
0.629 0.371 0.000
M05.1 Rheumatoid lung disease
0.629 0.371 0.000
M05.0 Felty's syndrome
0.629 0.371 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.628 0.372 0.000
M40-M43 Deforming dorsopathies
0.628 0.372 0.000
Q28 Other congenital malformations of circulatory system
0.627 0.373 0.000
S09 Other and unspecified injuries of head
0.627 0.373 0.000
Y42.7 Androgens and anabolic congeners
0.627 0.373 0.000
I31 Other diseases of pericardium
0.627 0.373 0.000
C50-C50 Malignant neoplasm of breast
0.627 0.373 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.625 0.374 0.000
N60.9 Benign mammary dysplasia, unspecified
0.625 0.375 0.000
I44 Atrioventricular and left bundle-branch block
0.625 0.375 0.000
D37.4 Colon
0.624 0.376 0.000
N70 Salpingitis and oophoritis
0.624 0.376 0.000
H10.9 Conjunctivitis, unspecified
0.624 0.376 0.000
H57.8 Other specified disorders of eye and adnexa
0.623 0.377 0.000
H11.0 Pterygium
0.623 0.377 0.000
B33 Other viral diseases, not elsewhere classified
0.623 0.377 0.000
B30 Viral conjunctivitis
0.623 0.377 0.000
B27 Infectious mononucleosis
0.623 0.377 0.000
B26 Mumps
0.623 0.377 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.623 0.377 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.622 0.378 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.621 0.379 0.000
T63.4 Venom of other arthropods
0.621 0.379 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.621 0.379 0.000
I86 Varicose veins of other sites
0.621 0.379 0.000
X23 Contact with hornets, wasps and bees
0.620 0.380 0.000
R00 Abnormalities of heart beat
0.620 0.380 0.000
Q63 Other congenital malformations of kidney
0.620 0.380 0.000
H25-H28 Disorders of lens
0.620 0.380 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.620 0.380 0.000
S62 Fracture at wrist and hand level
0.619 0.381 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.618 0.382 0.000
C44.8 Overlapping lesion of skin
0.618 0.382 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.617 0.382 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.617 0.382 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.617 0.382 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.617 0.382 0.000
Q61 Cystic kidney disease
0.616 0.384 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.615 0.385 0.000
H53.9 Visual disturbance, unspecified
0.615 0.385 0.000
S60 Superficial injury of wrist and hand
0.615 0.385 0.000
H53.8 Other visual disturbances
0.615 0.385 0.000
D06.9 Cervix, unspecified
0.614 0.386 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.614 0.386 0.000
S82.6 Fracture of lateral malleolus
0.614 0.386 0.000
W07 Fall involving chair
0.613 0.387 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.613 0.387 0.000
S06.5 Traumatic subdural haemorrhage
0.612 0.387 0.000
T78.4 Allergy, unspecified
0.612 0.387 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.611 0.389 0.000
J14 Pneumonia due to Haemophilus influenzae
0.611 0.389 0.000
S82.4 Fracture of fibula alone
0.611 0.389 0.000
C44.2 Skin of ear and external auricular canal
0.610 0.390 0.000
T51 Toxic effect of alcohol
0.610 0.390 0.000
N95 Menopausal and other perimenopausal disorders
0.609 0.391 0.000
S51 Open wound of forearm
0.609 0.391 0.000
H18 Other disorders of cornea
0.608 0.391 0.000
N80 Endometriosis
0.608 0.392 0.000
B19 Unspecified viral hepatitis
0.607 0.392 0.000
B16 Acute hepatitis B
0.607 0.392 0.000
B15 Acute hepatitis A
0.607 0.392 0.000
C44.7 Skin of lower limb, including hip
0.607 0.393 0.000
S79 Other and unspecified injuries of hip and thigh
0.607 0.393 0.000
C34 Malignant neoplasm of bronchus and lung
0.606 0.394 0.000
M94 Other disorders of cartilage
0.606 0.394 0.000
M14.6 Neuropathic arthropathy
0.606 0.394 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.606 0.394 0.000
S70 Superficial injury of hip and thigh
0.605 0.395 0.000
S01.0 Open wound of scalp
0.605 0.395 0.000
R42 Dizziness and giddiness
0.605 0.395 0.000
Q21.1 Atrial septal defect
0.604 0.396 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.604 0.396 0.000
C74 Malignant neoplasm of adrenal gland
0.604 0.396 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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