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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115281334
log Bayes Factor = 15.0554
Chromosome 4   position 78,595,878  (GRCh37) Explore rs115281334 on Ensembl!
Variant rs115281334 is part of Cluster X0161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.992 0.008 0.000
M20 Acquired deformities of fingers and toes
0.992 0.008 0.000
O60-O75 Complications of labour and delivery
0.989 0.011 0.000
Chapter II Neoplasms
0.987 0.013 0.000
Chapter XXI Factors influencing health status and contact with health services
0.984 0.016 0.000
R50-R69 General symptoms and signs
0.983 0.017 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.982 0.018 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.978 0.022 0.000
R00 Abnormalities of heart beat
0.978 0.022 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.971 0.029 0.000
M20.2 Hallux rigidus
0.970 0.030 0.000
Z51 Other medical care
0.968 0.032 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.963 0.037 0.000
F30-F39 Mood [affective] disorders
0.953 0.047 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.953 0.047 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.951 0.049 0.000
R51 Headache
0.951 0.049 0.000
R05 Cough
0.947 0.053 0.000
Chapter VI Diseases of the nervous system
0.945 0.055 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.941 0.059 0.000
Z51.5 Palliative care
0.941 0.059 0.000
R00.1 Bradycardia, unspecified
0.934 0.066 0.000
M20.4 Other hammer toe(s) (acquired)
0.933 0.067 0.000
S00-S09 Injuries to the head
0.932 0.068 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.932 0.068 0.000
Z51.2 Other chemotherapy
0.931 0.069 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.929 0.071 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.927 0.073 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.922 0.078 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.920 0.080 0.000
F41 Other anxiety disorders
0.919 0.081 0.000
O70 Perineal laceration during delivery
0.912 0.088 0.000
F32 Depressive episode
0.910 0.090 0.000
Chapter IX Diseases of the circulatory system
0.910 0.090 0.000
N80 Endometriosis
0.909 0.091 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.909 0.091 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.908 0.092 0.000
R00.2 Palpitations
0.903 0.097 0.000
R59 Enlarged lymph nodes
0.899 0.100 0.000
G20-G26 Extrapyramidal and movement disorders
0.893 0.107 0.000
M25 Other joint disorders, not elsewhere classified
0.892 0.108 0.000
N60-N64 Disorders of breast
0.889 0.111 0.000
Chapter XX External causes of morbidity and mortality
0.888 0.112 0.000
N85.1 Endometrial adenomatous hyperplasia
0.886 0.114 0.000
F41.9 Anxiety disorder, unspecified
0.886 0.114 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.885 0.115 0.000
S40-S49 Injuries to the shoulder and upper arm
0.883 0.117 0.000
N80.0 Endometriosis of uterus
0.878 0.122 0.000
S01 Open wound of head
0.876 0.124 0.000
C79 Secondary malignant neoplasm of other sites
0.876 0.124 0.000
M34 Systemic sclerosis
0.875 0.125 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.872 0.128 0.000
F32.9 Depressive episode, unspecified
0.872 0.128 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.867 0.133 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.864 0.136 0.000
R53 Malaise and fatigue
0.860 0.140 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.860 0.140 0.000
N17-N19 Renal failure
0.858 0.142 0.000
O63 Long labour
0.856 0.144 0.000
M80-M85 Disorders of bone density and structure
0.854 0.146 0.000
M20.0 Deformity of finger(s)
0.854 0.146 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.853 0.147 0.000
G20 Parkinson's disease
0.849 0.151 0.000
R94 Abnormal results of function studies
0.848 0.152 0.000
R03.1 Nonspecific low blood-pressure reading
0.847 0.153 0.000
O36 Maternal care for other known or suspected foetal problems
0.839 0.161 0.000
S80-S89 Injuries to the knee and lower leg
0.838 0.162 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.829 0.171 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.826 0.174 0.000
M86-M90 Other osteopathies
0.825 0.175 0.000
S70-S79 Injuries to the hip and thigh
0.823 0.176 0.000
N72 Inflammatory disease of cervix uteri
0.822 0.178 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.822 0.178 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.821 0.179 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.821 0.179 0.000
C80 Malignant neoplasm without specification of site
0.820 0.180 0.000
Chapter I Certain infectious and parasitic diseases
0.820 0.180 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.819 0.181 0.000
Z51.8 Other specified medical care
0.817 0.183 0.000
O70.1 Second degree perineal laceration during delivery
0.817 0.183 0.000
R52 Pain, not elsewhere classified
0.817 0.183 0.000
N85.0 Endometrial glandular hyperplasia
0.816 0.183 0.000
N85.4 Malposition of uterus
0.816 0.184 0.000
N30-N39 Other diseases of urinary system
0.815 0.185 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.815 0.185 0.000
M25.5 Pain in joint
0.813 0.187 0.000
F33 Recurrent depressive disorder
0.812 0.188 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.812 0.188 0.000
R60 Oedema, not elsewhere classified
0.809 0.191 0.000
C51-C58 Malignant neoplasms of female genital organs
0.809 0.191 0.000
R68 Other general symptoms and signs
0.808 0.191 0.000
S42 Fracture of shoulder and upper arm
0.805 0.195 0.000
R09.1 Pleurisy
0.801 0.199 0.000
N20-N23 Urolithiasis
0.799 0.201 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.799 0.201 0.000
O32.1 Maternal care for breech presentation
0.799 0.201 0.000
N76 Other inflammation of vagina and vulva
0.799 0.201 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.798 0.202 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.796 0.204 0.000
R59.1 Generalised enlarged lymph nodes
0.795 0.205 0.000
G90-G99 Other disorders of the nervous system
0.795 0.205 0.000
S02 Fracture of skull and facial bones
0.795 0.205 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.793 0.207 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.792 0.208 0.000
C64-C68 Malignant neoplasms of urinary tract
0.792 0.208 0.000
N95 Menopausal and other perimenopausal disorders
0.791 0.209 0.000
Z50 Care involving use of rehabilitation procedures
0.789 0.211 0.000
N83.2 Other and unspecified ovarian cysts
0.788 0.212 0.000
F60-F69 Disorders of adult personality and behaviour
0.788 0.212 0.000
R94.5 Abnormal results of liver function studies
0.785 0.215 0.000
N87 Dysplasia of cervix uteri
0.782 0.218 0.000
O70.2 Third degree perineal laceration during delivery
0.782 0.218 0.000
M45-M49 Spondylopathies
0.781 0.219 0.000
I30-I52 Other forms of heart disease
0.780 0.220 0.000
Z46 Fitting and adjustment of other devices
0.780 0.220 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.779 0.221 0.000
O80-O84 Delivery
0.779 0.221 0.000
R30-R39 Symptoms and signs involving the urinary system
0.776 0.224 0.000
O62 Abnormalities of forces of labour
0.775 0.224 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.775 0.225 0.000
Z42 Follow-up care involving plastic surgery
0.775 0.225 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.774 0.226 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.774 0.226 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.773 0.227 0.000
Chapter XXII Codes for special purposes
0.773 0.227 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.772 0.228 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.771 0.229 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.771 0.229 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.770 0.230 0.000
S01.8 Open wound of other parts of head
0.770 0.230 0.000
R54 Senility
0.769 0.231 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.769 0.231 0.000
I05-I09 Chronic rheumatic heart diseases
0.768 0.232 0.000
M31 Other necrotising vasculopathies
0.766 0.234 0.000
R09.2 Respiratory arrest
0.765 0.235 0.000
Z53.9 Procedure not carried out, unspecified reason
0.764 0.236 0.000
N60 Benign mammary dysplasia
0.763 0.237 0.000
M20.5 Other deformities of toe(s) (acquired)
0.762 0.237 0.000
N10-N16 Renal tubulo-interstitial diseases
0.762 0.238 0.000
Z35 Supervision of high-risk pregnancy
0.762 0.238 0.000
O43 Placental disorders
0.760 0.240 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.756 0.244 0.000
N63 Unspecified lump in breast
0.756 0.244 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.753 0.247 0.000
M65-M68 Disorders of synovium and tendon
0.753 0.247 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.753 0.247 0.000
Z43 Attention to artificial openings
0.752 0.248 0.000
S05 Injury of eye and orbit
0.751 0.249 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.751 0.249 0.000
S20-S29 Injuries to the thorax
0.751 0.249 0.000
D45 Polycythaemia vera
0.750 0.250 0.000
S60-S69 Injuries to the wrist and hand
0.750 0.250 0.000
M91-M94 Chondropathies
0.749 0.250 0.000
N40-N51 Diseases of male genital organs
0.749 0.251 0.000
R56 Convulsions, not elsewhere classified
0.749 0.251 0.000
O42 Premature rupture of membranes
0.748 0.252 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.748 0.252 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.747 0.253 0.000
Z37 Outcome of delivery
0.745 0.255 0.000
N25-N29 Other disorders of kidney and ureter
0.745 0.255 0.000
N83.0 Follicular cyst of ovary
0.743 0.257 0.000
Z52 Donors of organs and tissues
0.743 0.257 0.000
O36.6 Maternal care for excessive foetal growth
0.742 0.258 0.000
Z51.3 Blood transfusion without reported diagnosis
0.742 0.258 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.740 0.260 0.000
M20.3 Other deformity of hallux (acquired)
0.740 0.260 0.000
T79-T79 Certain early complications of trauma
0.739 0.260 0.000
M25.53 Pain in joint (Forearm)
0.739 0.261 0.000
M21 Other acquired deformities of limbs
0.737 0.263 0.000
C92 Myeloid leukaemia
0.736 0.264 0.000
M05-M14 Inflammatory polyarthropathies
0.736 0.264 0.000
R59.0 Localised enlarged lymph nodes
0.736 0.264 0.000
M34.8 Other forms of systemic sclerosis
0.735 0.265 0.000
S90-S99 Injuries to the ankle and foot
0.735 0.265 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.735 0.265 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.734 0.266 0.000
O63.0 Prolonged first stage (of labour)
0.734 0.266 0.000
N19 Unspecified renal failure
0.734 0.266 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.733 0.267 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.733 0.267 0.000
F41.2 Mixed anxiety and depressive disorder
0.731 0.269 0.000
T66-T78 Other and unspecified effects of external causes
0.730 0.270 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.729 0.271 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.728 0.271 0.000
Z49 Care involving dialysis
0.726 0.273 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.274 0.000
G30-G32 Other degenerative diseases of the nervous system
0.725 0.275 0.000
B25-B34 Other viral diseases
0.725 0.275 0.000
C80.9 Malignant neoplasm, unspecified
0.724 0.276 0.000
O32.2 Maternal care for transverse and oblique lie
0.724 0.276 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.724 0.276 0.000
D46 Myelodysplastic syndromes
0.722 0.278 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.722 0.278 0.000
M34.9 Systemic sclerosis, unspecified
0.721 0.279 0.000
N97 Female infertility
0.721 0.279 0.000
R60.0 Localised oedema
0.721 0.279 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.719 0.281 0.000
N83.1 Corpus luteum cyst
0.719 0.281 0.000
O66 Other obstructed labour
0.718 0.282 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.718 0.282 0.000
F99-F99 Unspecified mental disorder
0.718 0.282 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.718 0.282 0.000
F43 Reaction to severe stress, and adjustment disorders
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.286 0.000
M33 Dermatopolymyositis
0.713 0.286 0.000
M32 Systemic lupus erythematosus
0.713 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.286 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F80-F89 Disorders of psychological development
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.713 0.287 0.000
D70 Agranulocytosis
0.712 0.288 0.000
D00-D09 In situ neoplasms
0.712 0.288 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.711 0.289 0.000
S01.0 Open wound of scalp
0.710 0.290 0.000
O74 Complications of anaesthesia during labour and delivery
0.709 0.291 0.000
O73 Retained placenta and membranes, without haemorrhage
0.709 0.291 0.000
O71 Other obstetric trauma
0.709 0.291 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.709 0.291 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.709 0.291 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.709 0.291 0.000
O61 Failed induction of labour
0.709 0.291 0.000
O60 Preterm delivery
0.709 0.291 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.707 0.292 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.292 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.707 0.292 0.000
S06 Intracranial injury
0.707 0.293 0.000
N80.8 Other endometriosis
0.707 0.293 0.000
O00-O08 Pregnancy with abortive outcome
0.706 0.294 0.000
S81 Open wound of lower leg
0.705 0.295 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.705 0.295 0.000
R62 Lack of expected normal physiological development
0.705 0.295 0.000
R57 Shock, not elsewhere classified
0.705 0.295 0.000
R64 Cachexia
0.705 0.295 0.000
R58 Haemorrhage, not elsewhere classified
0.705 0.295 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.704 0.296 0.000
M24 Other specific joint derangements
0.704 0.296 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.704 0.296 0.000
N18 Chronic renal failure
0.702 0.298 0.000
F29 Unspecified nonorganic psychosis
0.702 0.298 0.000
N35 Urethral stricture
0.702 0.298 0.000
Z54 Convalescence
0.701 0.299 0.000
Z44 Fitting and adjustment of external prosthetic device
0.701 0.299 0.000
M80 Osteoporosis with pathological fracture
0.700 0.300 0.000
S82 Fracture of lower leg, including ankle
0.700 0.300 0.000
D41.4 Bladder
0.700 0.300 0.000
N21 Calculus of lower urinary tract
0.699 0.301 0.000
O72 Postpartum haemorrhage
0.698 0.302 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.698 0.302 0.000
S42.0 Fracture of clavicle
0.698 0.302 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.698 0.302 0.000
M40-M43 Deforming dorsopathies
0.697 0.303 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.697 0.303 0.000
N98 Complications associated with artificial fertilisation
0.696 0.304 0.000
N91 Absent, scanty and rare menstruation
0.696 0.304 0.000
N82 Fistulae involving female genital tract
0.696 0.304 0.000
N96 Habitual aborter
0.696 0.304 0.000
F22 Persistent delusional disorders
0.696 0.304 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.695 0.305 0.000
N99-N99 Other disorders of the genitourinary system
0.695 0.305 0.000
V10-V19 Pedal cyclist injured in transport accident
0.695 0.305 0.000
C91 Lymphoid leukaemia
0.695 0.305 0.000
R39 Other symptoms and signs involving the urinary system
0.695 0.305 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.695 0.305 0.000
G12 Spinal muscular atrophy and related syndromes
0.695 0.305 0.000
Z51.9 Medical care, unspecified
0.694 0.306 0.000
Z51.6 Desensitisation to allergens
0.694 0.306 0.000
I27 Other pulmonary heart diseases
0.694 0.306 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.694 0.306 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.693 0.307 0.000
N89 Other noninflammatory disorders of vagina
0.692 0.308 0.000
M81 Osteoporosis without pathological fracture
0.692 0.308 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.691 0.309 0.000
O45 Premature separation of placenta [abruptio placentae]
0.691 0.309 0.000
O44 Placenta praevia
0.691 0.309 0.000
O41 Other disorders of amniotic fluid and membranes
0.691 0.309 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.691 0.309 0.000
O33 Maternal care for known or suspected disproportion
0.691 0.309 0.000
O31 Complications specific to multiple gestation
0.691 0.309 0.000
O30 Multiple gestation
0.691 0.309 0.000
O40 Polyhydramnios
0.691 0.309 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.690 0.310 0.000
S01.2 Open wound of nose
0.689 0.310 0.000
Z47 Other orthopaedic follow-up care
0.689 0.311 0.000
A30-A49 Other bacterial diseases
0.689 0.311 0.000
S72 Fracture of femur
0.689 0.311 0.000
M70-M79 Other soft tissue disorders
0.688 0.312 0.000
X50-X57 Overexertion, travel and privation
0.688 0.312 0.000
N13 Obstructive and reflux uropathy
0.688 0.312 0.000
Q60-Q64 Congenital malformations of the urinary system
0.687 0.313 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.313 0.000
S50-S59 Injuries to the elbow and forearm
0.686 0.314 0.000
F38 Other mood [affective] disorders
0.683 0.317 0.000
F34 Persistent mood [affective] disorders
0.683 0.317 0.000
F30 Manic episode
0.683 0.317 0.000
F39 Unspecified mood [affective] disorder
0.683 0.317 0.000
R68.8 Other specified general symptoms and signs
0.683 0.317 0.000
F48 Other neurotic disorders
0.683 0.317 0.000
F45 Somatoform disorders
0.683 0.317 0.000
F44 Dissociative [conversion] disorders
0.683 0.317 0.000
F42 Obsessive-compulsive disorder
0.683 0.317 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.682 0.317 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.682 0.318 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.681 0.319 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.681 0.319 0.000
R35 Polyuria
0.681 0.319 0.000
I51 Complications and ill-defined descriptions of heart disease
0.680 0.320 0.000
Z32 Pregnancy examination and test
0.679 0.321 0.000
F40 Phobic anxiety disorders
0.678 0.322 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.678 0.322 0.000
N76.2 Acute vulvitis
0.676 0.324 0.000
Z51.1 Chemotherapy session for neoplasm
0.675 0.325 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.675 0.325 0.000
N85.7 Haematometra
0.675 0.325 0.000
N85.6 Intra-uterine synechiae
0.675 0.325 0.000
N85.5 Inversion of uterus
0.675 0.325 0.000
N85.3 Subinvolution of uterus
0.675 0.325 0.000
N71 Inflammatory disease of uterus, except cervix
0.674 0.326 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.673 0.326 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.674 0.326 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.673 0.327 0.000
G25 Other extrapyramidal and movement disorders
0.673 0.327 0.000
R59.9 Enlarged lymph nodes, unspecified
0.673 0.327 0.000
I60-I69 Cerebrovascular diseases
0.672 0.327 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.672 0.328 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.672 0.328 0.000
V20-V29 Motorcycle rider injured in transport accident
0.671 0.329 0.000
Z50.2 Alcohol rehabilitation
0.671 0.329 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.671 0.329 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.671 0.329 0.000
Z29 Need for other prophylactic measures
0.670 0.329 0.000
N48 Other disorders of penis
0.670 0.329 0.000
S01.3 Open wound of ear
0.670 0.330 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.669 0.331 0.000
O63.1 Prolonged second stage (of labour)
0.669 0.331 0.000
S08 Traumatic amputation of part of head
0.669 0.331 0.000
S07 Crushing injury of head
0.669 0.331 0.000
S04 Injury of cranial nerves
0.669 0.331 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.669 0.331 0.000
F33.9 Recurrent depressive disorder, unspecified
0.668 0.332 0.000
S01.9 Open wound of head, part unspecified
0.668 0.332 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.668 0.332 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.668 0.332 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.668 0.332 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.668 0.332 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.668 0.332 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.668 0.332 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.668 0.332 0.000
R06 Abnormalities of breathing
0.668 0.332 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.668 0.332 0.000
M25.7 Osteophyte
0.668 0.332 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.667 0.333 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.667 0.333 0.000
N88 Other noninflammatory disorders of cervix uteri
0.666 0.334 0.000
R94.4 Abnormal results of kidney function studies
0.666 0.334 0.000
T87 Complications peculiar to reattachment and amputation
0.666 0.334 0.000
T86 Failure and rejection of transplanted organs and tissues
0.666 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.666 0.334 0.000
N30 Cystitis
0.665 0.335 0.000
Z41 Procedures for purposes other than remedying health state
0.665 0.335 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.665 0.335 0.000
O36.5 Maternal care for poor foetal growth
0.664 0.336 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.662 0.338 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.662 0.338 0.000
D75 Other diseases of blood and blood-forming organs
0.661 0.339 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.661 0.339 0.000
C95 Leukaemia of unspecified cell type
0.661 0.339 0.000
C94 Other leukaemias of specified cell type
0.661 0.339 0.000
C93 Monocytic leukaemia
0.661 0.339 0.000
C88 Malignant immunoproliferative diseases
0.661 0.339 0.000
C86 Other specified types of T/NK-cell lymphoma
0.661 0.339 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.661 0.339 0.000
C81 Hodgkin's disease
0.661 0.339 0.000
Z50.0 Cardiac rehabilitation
0.660 0.340 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.660 0.340 0.000
R09.3 Abnormal sputum
0.660 0.340 0.000
R09.0 Asphyxia
0.660 0.340 0.000
F41.8 Other specified anxiety disorders
0.659 0.341 0.000
F41.3 Other mixed anxiety disorders
0.659 0.341 0.000
F41.1 Generalised anxiety disorder
0.659 0.341 0.000
O48 Prolonged pregnancy
0.659 0.341 0.000
Z39 Postpartum care and examination
0.659 0.341 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.659 0.341 0.000
L40-L45 Papulosquamous disorders
0.658 0.342 0.000
Z50.8 Care involving use of rehabilitation procedures
0.658 0.342 0.000
F20 Schizophrenia
0.658 0.342 0.000
M47 Spondylosis
0.657 0.343 0.000
B34 Viral infection of unspecified site
0.657 0.343 0.000
N95.2 Postmenopausal atrophic vaginitis
0.657 0.343 0.000
M88 Paget's disease of bone [osteitis deformans]
0.657 0.343 0.000
O47 False labour
0.657 0.343 0.000
C85.1 B-cell lymphoma, unspecified
0.657 0.343 0.000
S42.2 Fracture of upper end of humerus
0.657 0.343 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.656 0.344 0.000
G62 Other polyneuropathies
0.656 0.344 0.000
I42 Cardiomyopathy
0.655 0.345 0.000
Z35.5 Supervision of elderly primigravida
0.655 0.345 0.000
R52.9 Pain, unspecified
0.655 0.345 0.000
N80.9 Endometriosis, unspecified
0.654 0.345 0.000
O70.9 Perineal laceration during delivery, unspecified
0.654 0.346 0.000
O70.3 Fourth degree perineal laceration during delivery
0.654 0.346 0.000
N00-N08 Glomerular diseases
0.654 0.346 0.000
S01.1 Open wound of eyelid and periocular area
0.653 0.347 0.000
Z37.0 Single live birth
0.653 0.347 0.000
R81 Glycosuria
0.653 0.347 0.000
C67 Malignant neoplasm of bladder
0.653 0.347 0.000
F32.8 Other depressive episodes
0.653 0.347 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.653 0.347 0.000
F32.1 Moderate depressive episode
0.653 0.347 0.000
F32.0 Mild depressive episode
0.653 0.347 0.000
I00-I02 Acute rheumatic fever
0.652 0.348 0.000
N80.6 Endometriosis in cutaneous scar
0.652 0.348 0.000
N80.5 Endometriosis of intestine
0.652 0.348 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.652 0.348 0.000
N80.2 Endometriosis of Fallopian tube
0.652 0.348 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.651 0.348 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.651 0.349 0.000
N83.7 Haematoma of broad ligament
0.651 0.349 0.000
N83.6 Haematosalpinx
0.651 0.349 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.651 0.349 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.651 0.349 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.651 0.349 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.649 0.351 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.649 0.351 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.648 0.352 0.000
W20-W49 Exposure to inanimate mechanical forces
0.648 0.352 0.000
N86 Erosion and ectropion of cervix uteri
0.648 0.352 0.000
Z34 Supervision of normal pregnancy
0.648 0.352 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.648 0.352 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.647 0.352 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.647 0.353 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.646 0.353 0.000
M25.54 Pain in joint (Hand)
0.646 0.354 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.646 0.354 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.644 0.356 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.643 0.357 0.000
S02.4 Fracture of malar and maxillary bones
0.642 0.357 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.642 0.357 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.642 0.358 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.641 0.358 0.000
G91 Hydrocephalus
0.641 0.359 0.000
W00-W19 Falls
0.640 0.360 0.000
G24 Dystonia
0.640 0.360 0.000
G23 Other degenerative diseases of basal ganglia
0.640 0.360 0.000
G21 Secondary Parkinsonism
0.640 0.360 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.640 0.360 0.000
G22 Parkinsonism in diseases classified elsewhere
0.640 0.360 0.000
M25.9 Joint disorder, unspecified
0.640 0.360 0.000
M25.8 Other specified joint disorders
0.640 0.360 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.640 0.360 0.000
M25.3 Other instability of joint
0.640 0.360 0.000
M25.2 Flail joint
0.640 0.360 0.000
M25.1 Fistula of joint
0.640 0.360 0.000
M25.0 Haemarthrosis
0.640 0.360 0.000
I44 Atrioventricular and left bundle-branch block
0.639 0.361 0.000
F60 Specific personality disorders
0.639 0.361 0.000
C54 Malignant neoplasm of corpus uteri
0.639 0.361 0.000
Q50-Q56 Congenital malformations of genital organs
0.639 0.361 0.000
N61 Inflammatory disorders of breast
0.638 0.362 0.000
Z46.6 Fitting and adjustment of urinary device
0.638 0.362 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.637 0.363 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.637 0.363 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.636 0.364 0.000
Y35-Y36 Legal intervention and operations of war
0.636 0.364 0.000
Y10-Y34 Event of undetermined intent
0.636 0.364 0.000
Y00-Y09 Assault
0.636 0.364 0.000
X85-X99 Assault
0.636 0.364 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.636 0.364 0.000
X30-X39 Exposure to forces of nature
0.636 0.364 0.000
X20-X29 Contact with venomous animals and plants
0.636 0.364 0.000
X10-X19 Contact with heat and hot substances
0.636 0.364 0.000
X00-X09 Exposure to smoke, fire and flames
0.636 0.364 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.636 0.364 0.000
W75-W84 Other accidental threats to breathing
0.636 0.364 0.000
W65-W74 Accidental drowning and submersion
0.636 0.364 0.000
W50-W64 Exposure to animate mechanical forces
0.636 0.364 0.000
V98-V99 Other and unspecified transport accidents
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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