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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115322418
log Bayes Factor = 13.4298
Chromosome 1   position 27,762,459  (GRCh37) Explore rs115322418 on Ensembl!
Variant rs115322418 is part of Cluster X0033

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
D10-D36 Benign neoplasms
0.996 0.004 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
R50-R69 General symptoms and signs
0.992 0.008 0.000
J90-J94 Other diseases of pleura
0.988 0.012 0.000
I30-I52 Other forms of heart disease
0.979 0.021 0.000
Chapter XXI Factors influencing health status and contact with health services
0.976 0.024 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.969 0.031 0.000
C79 Secondary malignant neoplasm of other sites
0.968 0.032 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.964 0.036 0.000
Chapter V Mental and behavioural disorders
0.962 0.038 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.962 0.038 0.000
Chapter XX External causes of morbidity and mortality
0.958 0.042 0.000
D12.6 Colon, unspecified
0.956 0.044 0.000
J90 Pleural effusion, not elsewhere classified
0.953 0.047 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.951 0.049 0.000
R53 Malaise and fatigue
0.951 0.049 0.000
D17 Benign lipomatous neoplasm
0.947 0.053 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.946 0.054 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.945 0.055 0.000
D12.3 Transverse colon
0.936 0.064 0.000
E70-E90 Metabolic disorders
0.935 0.065 0.000
Chapter VIII Diseases of the ear and mastoid process
0.929 0.071 0.000
I44 Atrioventricular and left bundle-branch block
0.927 0.073 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.926 0.074 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.925 0.075 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.925 0.075 0.000
Z60 Problems related to social environment
0.924 0.076 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.923 0.077 0.000
I50 Heart failure
0.920 0.080 0.000
R52 Pain, not elsewhere classified
0.920 0.080 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.917 0.083 0.000
R94 Abnormal results of function studies
0.916 0.084 0.000
D12.0 Caecum
0.915 0.085 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.914 0.086 0.000
D12.5 Sigmoid colon
0.909 0.091 0.000
R56 Convulsions, not elsewhere classified
0.909 0.091 0.000
Z60.2 Living alone
0.905 0.095 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.901 0.099 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.899 0.101 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.895 0.105 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.885 0.115 0.000
J92 Pleural plaque
0.881 0.119 0.000
R94.5 Abnormal results of liver function studies
0.879 0.121 0.000
Z36 Antenatal screening
0.874 0.126 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.873 0.127 0.000
C34 Malignant neoplasm of bronchus and lung
0.871 0.129 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.870 0.130 0.000
S40-S49 Injuries to the shoulder and upper arm
0.869 0.131 0.000
R68 Other general symptoms and signs
0.867 0.133 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.867 0.133 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.866 0.134 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.860 0.140 0.000
Chapter XI Diseases of the digestive system
0.856 0.144 0.000
D12.2 Ascending colon
0.852 0.148 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.851 0.149 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.850 0.150 0.000
R56.8 Other and unspecified convulsions
0.849 0.151 0.000
J81 Pulmonary oedema
0.849 0.151 0.000
C51-C58 Malignant neoplasms of female genital organs
0.847 0.153 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.846 0.154 0.000
E87.6 Hypokalaemia
0.845 0.155 0.000
K70-K77 Diseases of liver
0.843 0.157 0.000
E86 Volume depletion
0.842 0.158 0.000
J84 Other interstitial pulmonary diseases
0.842 0.158 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.842 0.158 0.000
I60-I69 Cerebrovascular diseases
0.842 0.158 0.000
I80 Phlebitis and thrombophlebitis
0.842 0.158 0.000
I30 Acute pericarditis
0.841 0.159 0.000
J93 Pneumothorax
0.839 0.161 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.838 0.162 0.000
R52.2 Other chronic pain
0.831 0.169 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.831 0.169 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.824 0.176 0.000
I44.7 Left bundle-branch block, unspecified
0.823 0.177 0.000
C78.2 Secondary malignant neoplasm of pleura
0.823 0.177 0.000
R60 Oedema, not elsewhere classified
0.820 0.180 0.000
Chapter XXII Codes for special purposes
0.820 0.180 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.820 0.180 0.000
I45 Other conduction disorders
0.818 0.182 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.815 0.185 0.000
I27 Other pulmonary heart diseases
0.813 0.187 0.000
E87.7 Fluid overload
0.809 0.191 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.808 0.192 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.806 0.194 0.000
I49 Other cardiac arrhythmias
0.801 0.199 0.000
H65-H75 Diseases of middle ear and mastoid
0.797 0.203 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.797 0.203 0.000
R63 Symptoms and signs concerning food and fluid intake
0.796 0.204 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.795 0.205 0.000
I44.2 Atrioventricular block, complete
0.795 0.205 0.000
I50.0 Congestive heart failure
0.793 0.207 0.000
Chapter VI Diseases of the nervous system
0.792 0.208 0.000
R54 Senility
0.792 0.208 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.791 0.209 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.787 0.213 0.000
C78.7 Secondary malignant neoplasm of liver
0.786 0.214 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.786 0.214 0.000
I85 Oesophageal varices
0.785 0.215 0.000
H60-H62 Diseases of external ear
0.784 0.216 0.000
K50-K52 Noninfective enteritis and colitis
0.784 0.216 0.000
C34.9 Bronchus or lung, unspecified
0.783 0.217 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.782 0.218 0.000
D45 Polycythaemia vera
0.781 0.219 0.000
I42 Cardiomyopathy
0.780 0.220 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.780 0.220 0.000
Z33 Pregnant state, incidental
0.779 0.220 0.000
W00-W19 Falls
0.776 0.224 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.775 0.225 0.000
I50.1 Left ventricular failure
0.775 0.225 0.000
Y43 Primarily systemic agents
0.773 0.227 0.000
S42 Fracture of shoulder and upper arm
0.772 0.228 0.000
J20-J22 Other acute lower respiratory infections
0.771 0.229 0.000
Z57 Occupational exposure to risk-factors
0.771 0.229 0.000
J40-J47 Chronic lower respiratory diseases
0.771 0.229 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.771 0.229 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.770 0.230 0.000
X60-X84 Intentional self-harm
0.770 0.230 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.769 0.231 0.000
I44.0 Atrioventricular block, first degree
0.769 0.231 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.769 0.231 0.000
D00-D09 In situ neoplasms
0.768 0.232 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.768 0.232 0.000
T43.2 Other and unspecified antidepressants
0.767 0.233 0.000
C79.2 Secondary malignant neoplasm of skin
0.767 0.233 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.767 0.233 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.767 0.233 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.766 0.234 0.000
I50.9 Heart failure, unspecified
0.766 0.234 0.000
Chapter I Certain infectious and parasitic diseases
0.765 0.235 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.765 0.235 0.000
I05-I09 Chronic rheumatic heart diseases
0.765 0.235 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.762 0.238 0.000
F99-F99 Unspecified mental disorder
0.762 0.238 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.762 0.238 0.000
J60-J70 Lung diseases due to external agents
0.761 0.239 0.000
C34.3 Lower lobe, bronchus or lung
0.760 0.240 0.000
K76 Other diseases of liver
0.760 0.240 0.000
J92.9 Pleural plaque without asbestos
0.759 0.241 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.757 0.242 0.000
K50 Crohn's disease [regional enteritis]
0.757 0.243 0.000
R18 Ascites
0.755 0.245 0.000
K65-K67 Diseases of peritoneum
0.755 0.245 0.000
R52.1 Chronic intractable pain
0.754 0.245 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.754 0.246 0.000
J94 Other pleural conditions
0.752 0.247 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.749 0.251 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.749 0.251 0.000
Z48 Other surgical follow-up care
0.748 0.252 0.000
D12.7 Rectosigmoid junction
0.747 0.253 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.747 0.253 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.746 0.253 0.000
D12.4 Descending colon
0.746 0.254 0.000
Z32 Pregnancy examination and test
0.743 0.257 0.000
I30.9 Acute pericarditis, unspecified
0.742 0.258 0.000
R15 Faecal incontinence
0.742 0.258 0.000
C54 Malignant neoplasm of corpus uteri
0.739 0.261 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.739 0.261 0.000
R50 Fever of unknown origin
0.739 0.261 0.000
F03 Unspecified dementia
0.738 0.262 0.000
S20-S29 Injuries to the thorax
0.737 0.262 0.000
T17 Foreign body in respiratory tract
0.737 0.263 0.000
I71 Aortic aneurysm and dissection
0.737 0.263 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.737 0.263 0.000
Chapter XIV Diseases of the genitourinary system
0.736 0.264 0.000
F30-F39 Mood [affective] disorders
0.736 0.264 0.000
S90-S99 Injuries to the ankle and foot
0.734 0.266 0.000
R25 Abnormal involuntary movements
0.734 0.266 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.733 0.267 0.000
D11 Benign neoplasm of major salivary glands
0.733 0.267 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.732 0.267 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.732 0.268 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.732 0.268 0.000
F80-F89 Disorders of psychological development
0.732 0.268 0.000
J93.9 Pneumothorax, unspecified
0.732 0.268 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.729 0.271 0.000
K70 Alcoholic liver disease
0.728 0.272 0.000
I81 Portal vein thrombosis
0.727 0.273 0.000
H80-H83 Diseases of inner ear
0.727 0.273 0.000
O23 Infections of genito-urinary tract in pregnancy
0.725 0.275 0.000
I51 Complications and ill-defined descriptions of heart disease
0.725 0.275 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.724 0.276 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.723 0.277 0.000
J92.0 Pleural plaque with presence of asbestos
0.723 0.277 0.000
R60.9 Oedema, unspecified
0.722 0.277 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.722 0.278 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.722 0.278 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.722 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.721 0.279 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.721 0.279 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.719 0.281 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.719 0.281 0.000
E40-E46 Malnutrition
0.719 0.281 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.718 0.282 0.000
D34 Benign neoplasm of thyroid gland
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z36.8 Other antenatal screening
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.716 0.284 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R26 Abnormalities of gait and mobility
0.715 0.285 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
F01 Vascular dementia
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.714 0.285 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.285 0.000
S10-S19 Injuries to the neck
0.714 0.285 0.000
V80-V89 Other land transport accidents
0.714 0.286 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.714 0.286 0.000
D31 Benign neoplasm of eye and adnexa
0.714 0.286 0.000
D30 Benign neoplasm of urinary organs
0.714 0.286 0.000
D29 Benign neoplasm of male genital organs
0.714 0.286 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.714 0.286 0.000
D26 Other benign neoplasms of uterus
0.714 0.286 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.714 0.286 0.000
D19 Benign neoplasm of mesothelial tissue
0.714 0.286 0.000
D16 Benign neoplasm of bone and articular cartilage
0.714 0.286 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.714 0.286 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.714 0.286 0.000
D10 Benign neoplasm of mouth and pharynx
0.714 0.286 0.000
D12.9 Anus and anal canal
0.713 0.286 0.000
D12.1 Appendix
0.713 0.286 0.000
J91 Pleural effusion in conditions classified elsewhere
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.711 0.289 0.000
R62 Lack of expected normal physiological development
0.711 0.289 0.000
R57 Shock, not elsewhere classified
0.711 0.289 0.000
R64 Cachexia
0.711 0.289 0.000
R58 Haemorrhage, not elsewhere classified
0.711 0.289 0.000
S70-S79 Injuries to the hip and thigh
0.711 0.289 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.708 0.291 0.000
K08 Other disorders of teeth and supporting structures
0.708 0.292 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.706 0.294 0.000
K05 Gingivitis and periodontal diseases
0.706 0.294 0.000
K74 Fibrosis and cirrhosis of liver
0.706 0.294 0.000
G40-G47 Episodic and paroxysmal disorders
0.706 0.294 0.000
T39.1 4-Aminophenol derivatives
0.706 0.294 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.705 0.295 0.000
F00 Dementia in Alzheimer's disease
0.705 0.295 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.704 0.296 0.000
I26 Pulmonary embolism
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.703 0.297 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
I36 Nonrheumatic tricuspid valve disorders
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
I49.9 Cardiac arrhythmia, unspecified
0.702 0.298 0.000
O47 False labour
0.701 0.299 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.700 0.300 0.000
V20-V29 Motorcycle rider injured in transport accident
0.700 0.300 0.000
D23 Other benign neoplasms of skin
0.700 0.300 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.699 0.300 0.000
R52.0 Acute pain
0.699 0.301 0.000
E20-E35 Disorders of other endocrine glands
0.698 0.302 0.000
R68.8 Other specified general symptoms and signs
0.697 0.303 0.000
E87.2 Acidosis
0.697 0.303 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.697 0.303 0.000
T86 Failure and rejection of transplanted organs and tissues
0.696 0.304 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.695 0.305 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.695 0.305 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.695 0.305 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.695 0.305 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
T36 Poisoning by systemic antibiotics
0.695 0.305 0.000
K75 Other inflammatory liver diseases
0.695 0.305 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.694 0.306 0.000
Z48.8 Other specified surgical follow-up care
0.694 0.306 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.694 0.306 0.000
C79.6 Secondary malignant neoplasm of ovary
0.694 0.306 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.694 0.306 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.694 0.306 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.694 0.306 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.694 0.306 0.000
H61 Other disorders of external ear
0.692 0.308 0.000
I27.0 Primary pulmonary hypertension
0.691 0.309 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.691 0.309 0.000
S50-S59 Injuries to the elbow and forearm
0.691 0.309 0.000
I85.9 Oesophageal varices without bleeding
0.690 0.310 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.690 0.310 0.000
F70-F79 Mental retardation
0.690 0.310 0.000
F60-F69 Disorders of adult personality and behaviour
0.690 0.310 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.690 0.310 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.689 0.310 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.689 0.310 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.689 0.310 0.000
D22 Melanocytic naevi
0.689 0.311 0.000
D36 Benign neoplasm of other and unspecified sites
0.689 0.311 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.689 0.311 0.000
H90-H95 Other disorders of ear
0.689 0.311 0.000
K50.9 Crohn's disease, unspecified
0.688 0.312 0.000
Z36.9 Antenatal screening, unspecified
0.688 0.312 0.000
Z31 Procreative management
0.688 0.312 0.000
R30-R39 Symptoms and signs involving the urinary system
0.688 0.312 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.687 0.313 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.687 0.313 0.000
Y00-Y09 Assault
0.687 0.313 0.000
X85-X99 Assault
0.687 0.313 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.687 0.313 0.000
X50-X57 Overexertion, travel and privation
0.687 0.313 0.000
X30-X39 Exposure to forces of nature
0.687 0.313 0.000
X20-X29 Contact with venomous animals and plants
0.687 0.313 0.000
X10-X19 Contact with heat and hot substances
0.687 0.313 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.313 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
W75-W84 Other accidental threats to breathing
0.687 0.313 0.000
W65-W74 Accidental drowning and submersion
0.687 0.313 0.000
W50-W64 Exposure to animate mechanical forces
0.687 0.313 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.313 0.000
V95-V97 Air and space transport accidents
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.313 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.313 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.313 0.000
V40-V49 Car occupant injured in transport accident
0.687 0.313 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.313 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.313 0.000
O80-O84 Delivery
0.687 0.313 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.313 0.000
Y43.3 Other antineoplastic drugs
0.687 0.313 0.000
V10-V19 Pedal cyclist injured in transport accident
0.686 0.314 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.685 0.314 0.000
I33 Acute and subacute endocarditis
0.685 0.315 0.000
H65 Nonsuppurative otitis media
0.685 0.315 0.000
K72 Hepatic failure, not elsewhere classified
0.684 0.315 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.684 0.316 0.000
T66-T78 Other and unspecified effects of external causes
0.684 0.316 0.000
R61 Hyperhidrosis
0.684 0.316 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.683 0.317 0.000
I65.2 Occlusion and stenosis of carotid artery
0.683 0.317 0.000
Z65 Problems related to other psychosocial circumstances
0.682 0.318 0.000
Z64 Problems related to certain psychosocial circumstances
0.682 0.318 0.000
Z63 Other problems related to primary support group, including family circumstances
0.682 0.318 0.000
Z62 Other problems related to upbringing
0.682 0.318 0.000
Z61 Problems related to negative life events in childhood
0.682 0.318 0.000
Z59 Problems related to housing and economic circumstances
0.682 0.318 0.000
Z58 Problems related to physical environment
0.682 0.318 0.000
Z56 Problems related to employment and unemployment
0.682 0.318 0.000
Z55 Problems related to education and literacy
0.682 0.318 0.000
I87 Other disorders of veins
0.682 0.318 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.681 0.319 0.000
J43 Emphysema
0.680 0.320 0.000
I45.6 Preexcitation syndrome
0.679 0.321 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.679 0.321 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.679 0.321 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.679 0.321 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.679 0.321 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.679 0.321 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.678 0.322 0.000
Z34 Supervision of normal pregnancy
0.678 0.322 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.677 0.322 0.000
J80 Adult respiratory distress syndrome
0.677 0.322 0.000
S60-S69 Injuries to the wrist and hand
0.676 0.324 0.000
K50.1 Crohn's disease of large intestine
0.676 0.324 0.000
B95-B98 Bacterial, viral and other infectious agents
0.675 0.325 0.000
I86 Varicose veins of other sites
0.675 0.325 0.000
R94.3 Abnormal results of cardiovascular function studies
0.675 0.325 0.000
G30-G32 Other degenerative diseases of the nervous system
0.675 0.325 0.000
C80 Malignant neoplasm without specification of site
0.674 0.326 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.673 0.327 0.000
I95 Hypotension
0.673 0.327 0.000
T40.2 Other opioids
0.673 0.327 0.000
S40 Superficial injury of shoulder and upper arm
0.673 0.327 0.000
O20 Haemorrhage in early pregnancy
0.671 0.329 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.670 0.330 0.000
E10-E14 Diabetes mellitus
0.670 0.330 0.000
E88 Other metabolic disorders
0.670 0.330 0.000
E85 Amyloidosis
0.670 0.330 0.000
E84 Cystic fibrosis
0.670 0.330 0.000
E79 Disorders of purine and pyrimidine metabolism
0.670 0.330 0.000
E77 Disorders of glycoprotein metabolism
0.670 0.330 0.000
E76 Disorders of glycosaminoglycan metabolism
0.670 0.330 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.670 0.330 0.000
E74 Other disorders of carbohydrate metabolism
0.670 0.330 0.000
E73 Lactose intolerance
0.670 0.330 0.000
E72 Other disorders of amino-acid metabolism
0.670 0.330 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.670 0.330 0.000
E70 Disorders of aromatic amino-acid metabolism
0.670 0.330 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.670 0.330 0.000
M80-M85 Disorders of bone density and structure
0.670 0.330 0.000
T92 Sequelae of injuries of upper limb
0.669 0.331 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.668 0.331 0.000
Q60-Q64 Congenital malformations of the urinary system
0.668 0.331 0.000
I27.9 Pulmonary heart disease, unspecified
0.668 0.332 0.000
C64-C68 Malignant neoplasms of urinary tract
0.667 0.333 0.000
W20-W49 Exposure to inanimate mechanical forces
0.667 0.333 0.000
I44.6 Other and unspecified fascicular block
0.665 0.335 0.000
I44.5 Left posterior fascicular block
0.665 0.335 0.000
I44.4 Left anterior fascicular block
0.665 0.335 0.000
I44.3 Other and unspecified atrioventricular block
0.665 0.335 0.000
T18 Foreign body in alimentary tract
0.665 0.335 0.000
I42.0 Dilated cardiomyopathy
0.665 0.335 0.000
O85-O92 Complications predominantly related to the puerperium
0.664 0.336 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.663 0.336 0.000
S00-S09 Injuries to the head
0.663 0.337 0.000
Z39 Postpartum care and examination
0.663 0.337 0.000
Z38 Liveborn infants according to place of birth
0.663 0.337 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.663 0.337 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.663 0.337 0.000
C32 Malignant neoplasm of larynx
0.663 0.337 0.000
C31 Malignant neoplasm of accessory sinuses
0.663 0.337 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.663 0.337 0.000
C37 Malignant neoplasm of thymus
0.663 0.337 0.000
C33 Malignant neoplasm of trachea
0.663 0.337 0.000
Z60.9 Problem related to social environment, unspecified
0.663 0.337 0.000
Z60.8 Other problems related to social environment
0.663 0.337 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.663 0.337 0.000
Z60.4 Social exclusion and rejection
0.663 0.337 0.000
Z60.3 Acculturation difficulty
0.663 0.337 0.000
Z60.1 Atypical parenting situation
0.663 0.337 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.663 0.337 0.000
Q50-Q56 Congenital malformations of genital organs
0.662 0.338 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.662 0.338 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.662 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.662 0.338 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.662 0.338 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.662 0.338 0.000
C54.1 Endometrium
0.662 0.338 0.000
Z46 Fitting and adjustment of other devices
0.661 0.339 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.658 0.342 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.658 0.342 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.658 0.342 0.000
I88 Nonspecific lymphadenitis
0.657 0.343 0.000
I82 Other venous embolism and thrombosis
0.657 0.343 0.000
O21 Excessive vomiting in pregnancy
0.657 0.343 0.000
N93 Other abnormal uterine and vaginal bleeding
0.657 0.343 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.657 0.343 0.000
R94.7 Abnormal results of other endocrine function studies
0.657 0.343 0.000
R94.6 Abnormal results of thyroid function studies
0.657 0.343 0.000
R94.4 Abnormal results of kidney function studies
0.657 0.343 0.000
R94.2 Abnormal results of pulmonary function studies
0.657 0.343 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.657 0.343 0.000
R94.0 Abnormal results of function studies of central nervous system
0.657 0.343 0.000
R63.4 Abnormal weight loss
0.654 0.346 0.000
C53 Malignant neoplasm of cervix uteri
0.654 0.346 0.000
Z52 Donors of organs and tissues
0.654 0.346 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.652 0.348 0.000
J09-J18 Influenza and pneumonia
0.652 0.348 0.000
R56.0 Febrile convulsions
0.652 0.348 0.000
O44 Placenta praevia
0.651 0.348 0.000
K05.3 Chronic periodontitis
0.651 0.349 0.000
Y52 Agents primarily affecting the cardiovascular system
0.651 0.349 0.000
E83 Disorders of mineral metabolism
0.651 0.349 0.000
Z30 Contraceptive management
0.650 0.349 0.000
O24 Diabetes mellitus in pregnancy
0.650 0.350 0.000
G90-G99 Other disorders of the nervous system
0.650 0.350 0.000
T17.2 Foreign body in pharynx
0.649 0.351 0.000
R25.1 Tremor, unspecified
0.647 0.353 0.000
G47 Sleep disorders
0.646 0.354 0.000
I28 Other diseases of pulmonary vessels
0.646 0.354 0.000
E89.0 Postprocedural hypothyroidism
0.646 0.354 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.646 0.354 0.000
O42 Premature rupture of membranes
0.645 0.355 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.645 0.355 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.645 0.355 0.000
E87.5 Hyperkalaemia
0.645 0.355 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.645 0.355 0.000
E87.4 Mixed disorder of acid-base balance
0.645 0.355 0.000
E87.3 Alkalosis
0.645 0.355 0.000
K66 Other disorders of peritoneum
0.644 0.355 0.000
T39.0 Salicylates
0.643 0.357 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.643 0.357 0.000
R52.9 Pain, unspecified
0.643 0.357 0.000
I38 Endocarditis, valve unspecified
0.643 0.357 0.000
R17 Unspecified jaundice
0.642 0.358 0.000
I35 Nonrheumatic aortic valve disorders
0.642 0.358 0.000
Z49 Care involving dialysis
0.641 0.358 0.000
Y59 Other and unspecified vaccines and biological substances
0.641 0.359 0.000
Y58 Bacterial vaccines
0.641 0.359 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.641 0.359 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.641 0.359 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.641 0.359 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.641 0.359 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.641 0.359 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.641 0.359 0.000
Y48 Anaesthetics and therapeutic gases
0.641 0.359 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.641 0.359 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.641 0.359 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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