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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115384415
log Bayes Factor = 15.8504
Chromosome 1   position 95,333,551  (GRCh37) Explore rs115384415 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.992 0.008 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.992 0.008 0.000
Chapter XXI Factors influencing health status and contact with health services
0.992 0.008 0.000
M06 Other rheumatoid arthritis
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.990 0.010 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
H33 Retinal detachments and breaks
0.983 0.017 0.000
J30-J39 Other diseases of upper respiratory tract
0.982 0.018 0.000
I42 Cardiomyopathy
0.982 0.018 0.000
H52 Disorders of refraction and accommodation
0.982 0.018 0.000
M06.9 Rheumatoid arthritis, unspecified
0.982 0.018 0.000
I49 Other cardiac arrhythmias
0.979 0.021 0.000
J90-J94 Other diseases of pleura
0.979 0.021 0.000
I50 Heart failure
0.975 0.025 0.000
J34 Other disorders of nose and nasal sinuses
0.970 0.030 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.968 0.032 0.000
H52.1 Myopia
0.967 0.033 0.000
H33.0 Retinal detachment with retinal break
0.965 0.035 0.000
Z13 Special screening examination for other diseases and disorders
0.961 0.039 0.000
M20-M25 Other joint disorders
0.960 0.040 0.000
J90 Pleural effusion, not elsewhere classified
0.954 0.046 0.000
I51 Complications and ill-defined descriptions of heart disease
0.949 0.051 0.000
Chapter II Neoplasms
0.944 0.056 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.942 0.058 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.937 0.063 0.000
C15-C26 Malignant neoplasms of digestive organs
0.936 0.064 0.000
I42.0 Dilated cardiomyopathy
0.934 0.066 0.000
Chapter I Certain infectious and parasitic diseases
0.934 0.066 0.000
Chapter XX External causes of morbidity and mortality
0.934 0.066 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.932 0.068 0.000
I44 Atrioventricular and left bundle-branch block
0.930 0.070 0.000
I51.7 Cardiomegaly
0.928 0.072 0.000
I49.8 Other specified cardiac arrhythmias
0.928 0.072 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.927 0.073 0.000
I49.9 Cardiac arrhythmia, unspecified
0.926 0.074 0.000
J34.3 Hypertrophy of nasal turbinates
0.922 0.078 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.921 0.079 0.000
M80-M85 Disorders of bone density and structure
0.916 0.084 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.912 0.088 0.000
G40-G47 Episodic and paroxysmal disorders
0.912 0.088 0.000
M70-M79 Other soft tissue disorders
0.909 0.091 0.000
Z02 Examination and encounter for administrative purposes
0.909 0.091 0.000
C18 Malignant neoplasm of colon
0.902 0.098 0.000
J20-J22 Other acute lower respiratory infections
0.901 0.099 0.000
I50.9 Heart failure, unspecified
0.896 0.104 0.000
Z01.8 Other specified special examinations
0.896 0.104 0.000
I42.9 Cardiomyopathy, unspecified
0.890 0.110 0.000
I60-I69 Cerebrovascular diseases
0.890 0.110 0.000
M20 Acquired deformities of fingers and toes
0.887 0.113 0.000
M10 Gout
0.881 0.119 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.880 0.120 0.000
M07 Psoriatic and enteropathic arthropathies
0.880 0.120 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.878 0.122 0.000
H53-H54 Visual disturbances and blindness
0.877 0.123 0.000
G35 Multiple sclerosis
0.877 0.123 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.874 0.126 0.000
I50.0 Congestive heart failure
0.871 0.129 0.000
O00-O08 Pregnancy with abortive outcome
0.867 0.133 0.000
G90-G99 Other disorders of the nervous system
0.861 0.139 0.000
S50-S59 Injuries to the elbow and forearm
0.859 0.141 0.000
H33.2 Serous retinal detachment
0.856 0.144 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.855 0.145 0.000
C16 Malignant neoplasm of stomach
0.855 0.145 0.000
M13 Other arthritis
0.853 0.147 0.000
Z02.8 Other examinations for administrative purposes
0.852 0.148 0.000
H43-H45 Disorders of vitreous body and globe
0.849 0.151 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.848 0.152 0.000
I30 Acute pericarditis
0.846 0.154 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.845 0.155 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.844 0.156 0.000
J34.2 Deviated nasal septum
0.842 0.158 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.841 0.159 0.000
M21 Other acquired deformities of limbs
0.840 0.160 0.000
Chapter VIII Diseases of the ear and mastoid process
0.839 0.161 0.000
C15 Malignant neoplasm of oesophagus
0.836 0.164 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.834 0.166 0.000
H50 Other strabismus
0.831 0.169 0.000
M06.0 Seronegative rheumatoid arthritis
0.831 0.169 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.828 0.172 0.000
M79.8 Other specified soft tissue disorders
0.827 0.173 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.825 0.175 0.000
J32 Chronic sinusitis
0.824 0.176 0.000
I44.0 Atrioventricular block, first degree
0.823 0.177 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.823 0.177 0.000
H35 Other retinal disorders
0.822 0.178 0.000
H52.0 Hypermetropia
0.820 0.180 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.819 0.181 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.818 0.182 0.000
O60-O75 Complications of labour and delivery
0.818 0.182 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.817 0.183 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.816 0.184 0.000
Chapter XXII Codes for special purposes
0.816 0.184 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.816 0.184 0.000
C18.5 Splenic flexure
0.814 0.186 0.000
B35-B49 Mycoses
0.814 0.186 0.000
S10-S19 Injuries to the neck
0.812 0.188 0.000
M05 Seropositive rheumatoid arthritis
0.809 0.191 0.000
A00-A09 Intestinal infectious diseases
0.807 0.193 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.807 0.193 0.000
I50.1 Left ventricular failure
0.804 0.196 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.804 0.196 0.000
I49.4 Other and unspecified premature depolarisation
0.802 0.198 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.801 0.199 0.000
I45 Other conduction disorders
0.799 0.201 0.000
M22 Disorders of patella
0.797 0.203 0.000
M10.9 Gout, unspecified
0.796 0.204 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.795 0.205 0.000
M07.3 Other psoriatic arthropathies
0.794 0.205 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.794 0.206 0.000
S70-S79 Injuries to the hip and thigh
0.793 0.207 0.000
J22 Unspecified acute lower respiratory infection
0.792 0.208 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.792 0.208 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.790 0.210 0.000
C18.2 Ascending colon
0.790 0.210 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.790 0.210 0.000
J00-J06 Acute upper respiratory infections
0.789 0.210 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.788 0.211 0.000
J09-J18 Influenza and pneumonia
0.786 0.214 0.000
G40 Epilepsy
0.784 0.216 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.781 0.219 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.780 0.220 0.000
M81 Osteoporosis without pathological fracture
0.778 0.222 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.778 0.222 0.000
J93 Pneumothorax
0.778 0.222 0.000
M20.2 Hallux rigidus
0.775 0.225 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.772 0.228 0.000
M20.4 Other hammer toe(s) (acquired)
0.771 0.229 0.000
J39 Other diseases of upper respiratory tract
0.770 0.230 0.000
G20-G26 Extrapyramidal and movement disorders
0.768 0.232 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.767 0.233 0.000
G93 Other disorders of brain
0.765 0.235 0.000
H53 Visual disturbances
0.765 0.235 0.000
C79 Secondary malignant neoplasm of other sites
0.765 0.235 0.000
O80-O84 Delivery
0.762 0.238 0.000
I67 Other cerebrovascular diseases
0.760 0.240 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.757 0.243 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.757 0.243 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.757 0.243 0.000
H90-H95 Other disorders of ear
0.757 0.243 0.000
M65-M68 Disorders of synovium and tendon
0.757 0.243 0.000
I44.3 Other and unspecified atrioventricular block
0.756 0.244 0.000
I42.2 Other hypertrophic cardiomyopathy
0.755 0.245 0.000
G70-G73 Diseases of myoneural junction and muscle
0.755 0.245 0.000
H43 Disorders of vitreous body
0.754 0.246 0.000
D00-D09 In situ neoplasms
0.754 0.246 0.000
J94 Other pleural conditions
0.753 0.246 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.753 0.247 0.000
J60-J70 Lung diseases due to external agents
0.750 0.250 0.000
Y95 Nosocomial condition
0.748 0.252 0.000
Z22 Carrier of infectious disease
0.747 0.253 0.000
I78 Diseases of capillaries
0.747 0.253 0.000
I44.1 Atrioventricular block, second degree
0.746 0.254 0.000
H33.5 Other retinal detachments
0.744 0.256 0.000
M80 Osteoporosis with pathological fracture
0.743 0.257 0.000
C16.0 Cardia
0.742 0.258 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.741 0.258 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.741 0.259 0.000
M35 Other systemic involvement of connective tissue
0.741 0.259 0.000
C51-C58 Malignant neoplasms of female genital organs
0.740 0.260 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.739 0.261 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.738 0.262 0.000
M11 Other crystal arthropathies
0.737 0.263 0.000
I73 Other peripheral vascular diseases
0.736 0.264 0.000
I30.9 Acute pericarditis, unspecified
0.735 0.265 0.000
J20 Acute bronchitis
0.734 0.266 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.734 0.266 0.000
I38 Endocarditis, valve unspecified
0.733 0.266 0.000
H55-H59 Other disorders of eye and adnexa
0.733 0.267 0.000
H52.2 Astigmatism
0.733 0.267 0.000
C18.3 Hepatic flexure
0.732 0.268 0.000
V10-V19 Pedal cyclist injured in transport accident
0.732 0.268 0.000
C16.9 Stomach, unspecified
0.731 0.269 0.000
I71 Aortic aneurysm and dissection
0.731 0.269 0.000
W00-W19 Falls
0.731 0.269 0.000
Z01.6 Radiological examination, not elsewhere classified
0.730 0.270 0.000
Z04 Examination and observation for other reasons
0.730 0.270 0.000
M84 Disorders of continuity of bone
0.730 0.270 0.000
O85-O92 Complications predominantly related to the puerperium
0.730 0.270 0.000
C15.9 Oesophagus, unspecified
0.729 0.271 0.000
H33.3 Retinal breaks without detachment
0.728 0.272 0.000
I44.2 Atrioventricular block, complete
0.727 0.273 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.727 0.273 0.000
H10-H13 Disorders of conjunctiva
0.726 0.274 0.000
O04 Medical abortion
0.726 0.274 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.724 0.276 0.000
M31 Other necrotising vasculopathies
0.723 0.277 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.723 0.277 0.000
M79.0 Rheumatism, unspecified
0.722 0.278 0.000
B15-B19 Viral hepatitis
0.722 0.278 0.000
M13.9 Arthritis, unspecified
0.721 0.279 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.721 0.279 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.720 0.280 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.720 0.280 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.720 0.280 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.719 0.280 0.000
J36 Peritonsillar abscess
0.718 0.282 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.718 0.282 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.716 0.283 0.000
M12 Other specific arthropathies
0.716 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.283 0.000
M08 Juvenile arthritis
0.716 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
O70 Perineal laceration during delivery
0.716 0.284 0.000
H52.3 Anisometropia and aniseikonia
0.715 0.284 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.715 0.285 0.000
H50.0 Convergent concomitant strabismus
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.714 0.285 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.714 0.286 0.000
C18.9 Colon, unspecified
0.714 0.286 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.713 0.286 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.713 0.287 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.287 0.000
M20.5 Other deformities of toe(s) (acquired)
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.711 0.289 0.000
H31 Other disorders of choroid
0.711 0.289 0.000
H30 Chorioretinal inflammation
0.711 0.289 0.000
H51 Other disorders of binocular movement
0.711 0.289 0.000
H49 Paralytic strabismus
0.711 0.289 0.000
M06.8 Other specified rheumatoid arthritis
0.711 0.289 0.000
M06.4 Inflammatory polyarthropathy
0.711 0.289 0.000
M06.3 Rheumatoid nodule
0.711 0.289 0.000
M06.2 Rheumatoid bursitis
0.711 0.289 0.000
M06.1 Adult-onset Still's disease
0.711 0.289 0.000
S40-S49 Injuries to the shoulder and upper arm
0.710 0.290 0.000
T33-T35 Frostbite
0.710 0.290 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.710 0.290 0.000
T00-T07 Injuries involving multiple body regions
0.710 0.290 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.710 0.290 0.000
Z96 Presence of other functional implants
0.710 0.290 0.000
G45.4 Transient global amnesia
0.709 0.291 0.000
I72 Other aneurysm
0.709 0.291 0.000
Z10 Routine general health check-up of defined subpopulation
0.708 0.291 0.000
H36 Retinal disorders in diseases classified elsewhere
0.708 0.292 0.000
H34 Retinal vascular occlusions
0.707 0.293 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.706 0.294 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.294 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.706 0.294 0.000
J03 Acute tonsillitis
0.706 0.294 0.000
I31 Other diseases of pericardium
0.706 0.294 0.000
H33.4 Traction detachment of retina
0.705 0.295 0.000
H33.1 Retinoschisis and retinal cysts
0.705 0.295 0.000
J37 Chronic laryngitis and laryngotracheitis
0.704 0.296 0.000
I42.8 Other cardiomyopathies
0.704 0.296 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.704 0.296 0.000
I42.6 Alcoholic cardiomyopathy
0.704 0.296 0.000
I42.5 Other restrictive cardiomyopathy
0.704 0.296 0.000
I42.4 Endocardial fibroelastosis
0.704 0.296 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.704 0.296 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.704 0.296 0.000
H52.7 Disorder of refraction, unspecified
0.704 0.296 0.000
H52.6 Other disorders of refraction
0.704 0.296 0.000
H52.5 Disorders of accommodation
0.704 0.296 0.000
H52.4 Presbyopia
0.704 0.296 0.000
J92 Pleural plaque
0.704 0.296 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.704 0.296 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.704 0.296 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.704 0.296 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.704 0.296 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.704 0.296 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.704 0.296 0.000
B95-B98 Bacterial, viral and other infectious agents
0.704 0.296 0.000
H35.4 Peripheral retinal degeneration
0.703 0.297 0.000
I49.2 Junctional premature depolarisation
0.702 0.298 0.000
I49.1 Atrial premature depolarisation
0.702 0.298 0.000
M72 Fibroblastic disorders
0.702 0.298 0.000
O03 Spontaneous abortion
0.700 0.300 0.000
Z96.6 Presence of orthopaedic joint implants
0.700 0.300 0.000
I49.3 Ventricular premature depolarisation
0.699 0.301 0.000
J91 Pleural effusion in conditions classified elsewhere
0.699 0.301 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.698 0.302 0.000
J32.0 Chronic maxillary sinusitis
0.697 0.303 0.000
C18.6 Descending colon
0.696 0.304 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.695 0.304 0.000
M21.0 Valgus deformity, not elsewhere classified
0.695 0.304 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.695 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.694 0.306 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.694 0.306 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.306 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.693 0.307 0.000
M77 Other enthesopathies
0.691 0.308 0.000
W20-W49 Exposure to inanimate mechanical forces
0.689 0.310 0.000
S52 Fracture of forearm
0.690 0.310 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.689 0.311 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.689 0.311 0.000
Z13.5 Special screening examination for eye and ear disorders
0.689 0.311 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.689 0.311 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.689 0.311 0.000
Z13.2 Special screening examination for nutritional disorders
0.689 0.311 0.000
M21.6 Other acquired deformities of ankle and foot
0.688 0.312 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.688 0.312 0.000
M34 Systemic sclerosis
0.688 0.312 0.000
M33 Dermatopolymyositis
0.688 0.312 0.000
M32 Systemic lupus erythematosus
0.688 0.312 0.000
M30 Polyarteritis nodosa and related conditions
0.688 0.312 0.000
I05-I09 Chronic rheumatic heart diseases
0.687 0.313 0.000
M20.0 Deformity of finger(s)
0.686 0.313 0.000
S56 Injury of muscle and tendon at forearm level
0.685 0.315 0.000
C20 Malignant neoplasm of rectum
0.684 0.316 0.000
T90 Sequelae of injuries of head
0.684 0.316 0.000
M79.6 Pain in limb
0.684 0.316 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.684 0.316 0.000
H54 Blindness and low vision
0.684 0.316 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.683 0.317 0.000
H25-H28 Disorders of lens
0.683 0.317 0.000
T79-T79 Certain early complications of trauma
0.682 0.317 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.681 0.318 0.000
M10.99 Gout, unspecified (Site unspecified)
0.681 0.319 0.000
M22.4 Chondromalacia patellae
0.681 0.319 0.000
O70.0 First degree perineal laceration during delivery
0.681 0.319 0.000
I51.6 Cardiovascular disease, unspecified
0.681 0.319 0.000
I51.5 Myocardial degeneration
0.681 0.319 0.000
I51.4 Myocarditis, unspecified
0.681 0.319 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.681 0.319 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.681 0.319 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.681 0.319 0.000
I51.0 Cardiac septal defect, acquired
0.681 0.319 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.680 0.320 0.000
O02 Other abnormal products of conception
0.679 0.321 0.000
T82.3 Mechanical complication of other vascular grafts
0.678 0.321 0.000
M85 Other disorders of bone density and structure
0.678 0.322 0.000
C15.5 Lower third of oesophagus
0.678 0.322 0.000
M86-M90 Other osteopathies
0.677 0.322 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.677 0.323 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.677 0.323 0.000
H50.9 Strabismus, unspecified
0.677 0.323 0.000
H43.8 Other disorders of vitreous body
0.677 0.323 0.000
I74 Arterial embolism and thrombosis
0.676 0.324 0.000
A80-A89 Viral infections of the central nervous system
0.675 0.325 0.000
G93.3 Postviral fatigue syndrome
0.675 0.325 0.000
B37 Candidiasis
0.674 0.326 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.674 0.326 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.674 0.326 0.000
Z86 Personal history of certain other diseases
0.673 0.327 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.672 0.328 0.000
Z01.9 Special examination, unspecified
0.672 0.328 0.000
Z01.7 Laboratory examination
0.672 0.328 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.672 0.328 0.000
Z01.3 Examination of blood pressure
0.672 0.328 0.000
Z01.2 Dental examination
0.672 0.328 0.000
Z01.1 Examination of ears and hearing
0.672 0.328 0.000
Z01.0 Examination of eyes and vision
0.672 0.328 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.672 0.328 0.000
S90-S99 Injuries to the ankle and foot
0.672 0.328 0.000
B49 Unspecified mycosis
0.671 0.329 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.671 0.329 0.000
C21 Malignant neoplasm of anus and anal canal
0.671 0.329 0.000
C17 Malignant neoplasm of small intestine
0.671 0.329 0.000
C23 Malignant neoplasm of gallbladder
0.671 0.329 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.671 0.329 0.000
S51 Open wound of forearm
0.670 0.329 0.000
M81.9 Osteoporosis, unspecified
0.670 0.330 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.670 0.330 0.000
B99-B99 Other infectious diseases
0.670 0.330 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.670 0.330 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.670 0.330 0.000
B65-B83 Helminthiases
0.670 0.330 0.000
B50-B64 Protozoal diseases
0.670 0.330 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.670 0.330 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.670 0.330 0.000
A75-A79 Rickettsioses
0.670 0.330 0.000
A70-A74 Other diseases caused by chlamydiae
0.670 0.330 0.000
A65-A69 Other spirochaetal diseases
0.670 0.330 0.000
A20-A28 Certain zoonotic bacterial diseases
0.670 0.330 0.000
A15-A19 Tuberculosis
0.670 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.670 0.330 0.000
Y35-Y36 Legal intervention and operations of war
0.670 0.330 0.000
Y10-Y34 Event of undetermined intent
0.670 0.330 0.000
Y00-Y09 Assault
0.670 0.330 0.000
X85-X99 Assault
0.670 0.330 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.670 0.330 0.000
X30-X39 Exposure to forces of nature
0.670 0.330 0.000
X20-X29 Contact with venomous animals and plants
0.670 0.330 0.000
X10-X19 Contact with heat and hot substances
0.670 0.330 0.000
X00-X09 Exposure to smoke, fire and flames
0.670 0.330 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.670 0.330 0.000
W75-W84 Other accidental threats to breathing
0.670 0.330 0.000
W65-W74 Accidental drowning and submersion
0.670 0.330 0.000
W50-W64 Exposure to animate mechanical forces
0.670 0.330 0.000
V98-V99 Other and unspecified transport accidents
0.670 0.330 0.000
V95-V97 Air and space transport accidents
0.670 0.330 0.000
V90-V94 Water transport accidents
0.670 0.330 0.000
V80-V89 Other land transport accidents
0.670 0.330 0.000
V70-V79 Bus occupant injured in transport accident
0.670 0.330 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.670 0.330 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.670 0.330 0.000
V40-V49 Car occupant injured in transport accident
0.670 0.330 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.670 0.330 0.000
V20-V29 Motorcycle rider injured in transport accident
0.670 0.330 0.000
V01-V09 Pedestrian injured in transport accident
0.670 0.330 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.669 0.331 0.000
G30-G32 Other degenerative diseases of the nervous system
0.669 0.331 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.669 0.331 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.668 0.332 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.668 0.332 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.668 0.332 0.000
I44.6 Other and unspecified fascicular block
0.666 0.333 0.000
I44.5 Left posterior fascicular block
0.666 0.333 0.000
I44.4 Left anterior fascicular block
0.666 0.333 0.000
T43.2 Other and unspecified antidepressants
0.665 0.335 0.000
M45-M49 Spondylopathies
0.665 0.335 0.000
T17 Foreign body in respiratory tract
0.665 0.335 0.000
T87 Complications peculiar to reattachment and amputation
0.665 0.335 0.000
T86 Failure and rejection of transplanted organs and tissues
0.665 0.335 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.664 0.336 0.000
H91 Other hearing loss
0.661 0.339 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.660 0.339 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.660 0.340 0.000
Z13.1 Special screening examination for diabetes mellitus
0.660 0.340 0.000
G36 Other acute disseminated demyelination
0.660 0.340 0.000
I70 Atherosclerosis
0.660 0.340 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.660 0.340 0.000
S00-S09 Injuries to the head
0.660 0.340 0.000
M13.0 Polyarthritis, unspecified
0.659 0.341 0.000
O41 Other disorders of amniotic fluid and membranes
0.658 0.342 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.658 0.342 0.000
M79.5 Residual foreign body in soft tissue
0.657 0.343 0.000
Z22.3 Carrier of other specified bacterial diseases
0.657 0.343 0.000
A08 Viral and other specified intestinal infections
0.657 0.343 0.000
M83 Adult osteomalacia
0.656 0.343 0.000
M82 Osteoporosis in diseases classified elsewhere
0.656 0.343 0.000
M20.3 Other deformity of hallux (acquired)
0.656 0.343 0.000
T23 Burn and corrosion of wrist and hand
0.656 0.344 0.000
T91 Sequelae of injuries of neck and trunk
0.655 0.345 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.655 0.345 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.655 0.345 0.000
S72 Fracture of femur
0.655 0.345 0.000
M40-M43 Deforming dorsopathies
0.655 0.345 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.655 0.345 0.000
X60-X84 Intentional self-harm
0.654 0.345 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.654 0.346 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.653 0.346 0.000
G41 Status epilepticus
0.653 0.346 0.000
H53.9 Visual disturbance, unspecified
0.653 0.347 0.000
Z86.7 Personal history of diseases of the circulatory system
0.652 0.348 0.000
I45.9 Conduction disorder, unspecified
0.652 0.348 0.000
J39.8 Other specified diseases of upper respiratory tract
0.652 0.348 0.000
M76 Enthesopathies of lower limb, excluding foot
0.652 0.348 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.652 0.348 0.000
M71 Other bursopathies
0.652 0.348 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.652 0.348 0.000
C18.0 Caecum
0.652 0.348 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.652 0.348 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.651 0.349 0.000
Z02.9 Examination for administrative purposes, unspecified
0.651 0.349 0.000
Z02.7 Issue of medical certificate
0.651 0.349 0.000
Z02.6 Examination for insurance purposes
0.651 0.349 0.000
Z02.5 Examination for participation in sport
0.651 0.349 0.000
Z02.4 Examination for driving licence
0.651 0.349 0.000
Z02.3 Examination for recruitment to armed forces
0.651 0.349 0.000
Z02.2 Examination for admission to residential institution
0.651 0.349 0.000
Z02.1 Pre-employment examination
0.651 0.349 0.000
Z02.0 Examination for admission to educational institution
0.651 0.349 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.651 0.349 0.000
G91 Hydrocephalus
0.651 0.349 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.651 0.349 0.000
H18 Other disorders of cornea
0.650 0.350 0.000
H20 Iridocyclitis
0.648 0.352 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.648 0.352 0.000
H35.9 Retinal disorder, unspecified
0.648 0.352 0.000
T18 Foreign body in alimentary tract
0.647 0.353 0.000
C18.8 Overlapping lesion of colon
0.647 0.353 0.000
C18.1 Appendix
0.647 0.353 0.000
J03.9 Acute tonsillitis, unspecified
0.646 0.354 0.000
J21 Acute bronchiolitis
0.646 0.354 0.000
O44 Placenta praevia
0.646 0.354 0.000
C54 Malignant neoplasm of corpus uteri
0.645 0.355 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.644 0.356 0.000
H21 Other disorders of iris and ciliary body
0.641 0.359 0.000
M23 Internal derangement of knee
0.641 0.359 0.000
G20 Parkinson's disease
0.641 0.359 0.000
I45.5 Other specified heart block
0.640 0.359 0.000
J86 Pyothorax
0.640 0.360 0.000
D03 Melanoma in situ
0.640 0.360 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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