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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115573344
log Bayes Factor = 14.0832
Chromosome 3   position 27,887,025  (GRCh37) Explore rs115573344 on Ensembl!
Variant rs115573344 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.994 0.006 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.993 0.007 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
Chapter IX Diseases of the circulatory system
0.988 0.012 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.984 0.016 0.000
Z95.1 Presence of aortocoronary bypass graft
0.981 0.019 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.974 0.026 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.974 0.026 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.973 0.027 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.968 0.032 0.000
Y83.3 Surgical operation with formation of external stoma
0.968 0.032 0.000
C78.7 Secondary malignant neoplasm of liver
0.967 0.033 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.966 0.034 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.966 0.034 0.000
I20-I25 Ischaemic heart diseases
0.965 0.035 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.965 0.035 0.000
Z92 Personal history of medical treatment
0.965 0.035 0.000
I30-I52 Other forms of heart disease
0.963 0.037 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.959 0.041 0.000
I47 Paroxysmal tachycardia
0.952 0.048 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.950 0.050 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.950 0.050 0.000
Z92.3 Personal history of irradiation
0.946 0.054 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.945 0.055 0.000
Z36 Antenatal screening
0.935 0.065 0.000
I20 Angina pectoris
0.932 0.068 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.931 0.069 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.930 0.070 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.929 0.071 0.000
I47.1 Supraventricular tachycardia
0.928 0.072 0.000
T81 Complications of procedures, not elsewhere classified
0.926 0.074 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.926 0.074 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.922 0.078 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.920 0.080 0.000
Chapter I Certain infectious and parasitic diseases
0.920 0.080 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.915 0.085 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.914 0.085 0.000
I25 Chronic ischaemic heart disease
0.911 0.089 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.908 0.092 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.906 0.094 0.000
Z85 Personal history of malignant neoplasm
0.906 0.094 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.905 0.095 0.000
C79 Secondary malignant neoplasm of other sites
0.901 0.099 0.000
O80-O84 Delivery
0.898 0.102 0.000
G40-G47 Episodic and paroxysmal disorders
0.897 0.103 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.897 0.103 0.000
Z95.3 Presence of xenogenic heart valve
0.893 0.107 0.000
C77.2 Intra-abdominal lymph nodes
0.891 0.109 0.000
C15-C26 Malignant neoplasms of digestive organs
0.885 0.115 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.885 0.115 0.000
I25.1 Atherosclerotic heart disease
0.882 0.118 0.000
A30-A49 Other bacterial diseases
0.872 0.128 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.866 0.134 0.000
G43 Migraine
0.862 0.138 0.000
C91 Lymphoid leukaemia
0.862 0.138 0.000
H52 Disorders of refraction and accommodation
0.860 0.140 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.857 0.143 0.000
O82 Single delivery by Caesarean section
0.855 0.145 0.000
C77.8 Lymph nodes of multiple regions
0.851 0.149 0.000
Z36.9 Antenatal screening, unspecified
0.847 0.153 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.846 0.154 0.000
I20.8 Other forms of angina pectoris
0.841 0.159 0.000
H04 Disorders of lachrymal system
0.839 0.161 0.000
G43.9 Migraine, unspecified
0.837 0.163 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.836 0.164 0.000
Chapter XXII Codes for special purposes
0.834 0.166 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.833 0.167 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.832 0.168 0.000
C77.3 Axillary and upper limb lymph nodes
0.832 0.168 0.000
D00-D09 In situ neoplasms
0.832 0.168 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.831 0.168 0.000
C77.5 Intrapelvic lymph nodes
0.831 0.169 0.000
O36 Maternal care for other known or suspected foetal problems
0.831 0.169 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.826 0.174 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.826 0.174 0.000
O82.0 Delivery by elective Caesarean section
0.825 0.175 0.000
O00-O08 Pregnancy with abortive outcome
0.824 0.176 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.823 0.177 0.000
H25-H28 Disorders of lens
0.823 0.177 0.000
I44 Atrioventricular and left bundle-branch block
0.821 0.179 0.000
G20-G26 Extrapyramidal and movement disorders
0.821 0.179 0.000
C85.1 B-cell lymphoma, unspecified
0.817 0.183 0.000
H52.1 Myopia
0.814 0.186 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.813 0.187 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.812 0.188 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.812 0.188 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.811 0.189 0.000
Z34 Supervision of normal pregnancy
0.811 0.189 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.808 0.192 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.806 0.194 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.806 0.194 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.806 0.194 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.804 0.196 0.000
H40-H42 Glaucoma
0.802 0.198 0.000
R47-R49 Symptoms and signs involving speech and voice
0.802 0.198 0.000
G62 Other polyneuropathies
0.798 0.202 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.798 0.202 0.000
H30-H36 Disorders of choroid and retina
0.797 0.203 0.000
Z95.2 Presence of prosthetic heart valve
0.797 0.203 0.000
S20-S29 Injuries to the thorax
0.797 0.203 0.000
Z93 Artificial opening status
0.796 0.204 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.794 0.205 0.000
I20.9 Angina pectoris, unspecified
0.792 0.208 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.791 0.208 0.000
A41 Other septicaemia
0.790 0.210 0.000
R94 Abnormal results of function studies
0.790 0.210 0.000
Z96 Presence of other functional implants
0.789 0.211 0.000
C91.1 Chronic lymphocytic leukaemia
0.787 0.213 0.000
Chapter X Diseases of the respiratory system
0.786 0.214 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.784 0.216 0.000
C60-C63 Malignant neoplasms of male genital organs
0.783 0.217 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.783 0.217 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.779 0.221 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.779 0.221 0.000
Z88.5 Personal history of allergy to narcotic agent
0.775 0.225 0.000
M45-M49 Spondylopathies
0.775 0.225 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.774 0.226 0.000
T66-T78 Other and unspecified effects of external causes
0.770 0.230 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.769 0.231 0.000
Z36.8 Other antenatal screening
0.769 0.231 0.000
O36.8 Maternal care for other specified foetal problems
0.769 0.231 0.000
G90-G99 Other disorders of the nervous system
0.766 0.234 0.000
I25.5 Ischaemic cardiomyopathy
0.765 0.235 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.237 0.000
Z92.0 Personal history of contraception
0.763 0.237 0.000
S80-S89 Injuries to the knee and lower leg
0.763 0.237 0.000
Z13 Special screening examination for other diseases and disorders
0.762 0.238 0.000
M20-M25 Other joint disorders
0.761 0.239 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.760 0.240 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.760 0.240 0.000
Z97 Presence of other devices
0.759 0.241 0.000
I47.2 Ventricular tachycardia
0.757 0.243 0.000
Z33 Pregnant state, incidental
0.757 0.243 0.000
A49 Bacterial infection of unspecified site
0.754 0.246 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.754 0.246 0.000
I20.0 Unstable angina
0.754 0.246 0.000
H01 Other inflammation of eyelid
0.753 0.247 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.751 0.248 0.000
M23 Internal derangement of knee
0.751 0.249 0.000
J09-J18 Influenza and pneumonia
0.749 0.251 0.000
G70-G73 Diseases of myoneural junction and muscle
0.749 0.251 0.000
W00-W19 Falls
0.748 0.252 0.000
Z96.0 Presence of urogenital implants
0.748 0.252 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.747 0.253 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.747 0.253 0.000
C21 Malignant neoplasm of anus and anal canal
0.746 0.254 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.746 0.254 0.000
Y40 Systemic antibiotics
0.745 0.255 0.000
I60-I69 Cerebrovascular diseases
0.745 0.255 0.000
S40-S49 Injuries to the shoulder and upper arm
0.744 0.256 0.000
C20 Malignant neoplasm of rectum
0.744 0.256 0.000
C51-C58 Malignant neoplasms of female genital organs
0.743 0.257 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.742 0.257 0.000
I46 Cardiac arrest
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.741 0.259 0.000
Z83 Family history of other specific disorders
0.741 0.259 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.740 0.260 0.000
O44 Placenta praevia
0.740 0.260 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.740 0.260 0.000
I20.1 Angina pectoris with documented spasm
0.740 0.260 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.740 0.260 0.000
I24 Other acute ischaemic heart diseases
0.739 0.261 0.000
I31 Other diseases of pericardium
0.738 0.262 0.000
Chapter VIII Diseases of the ear and mastoid process
0.738 0.262 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.737 0.263 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.737 0.263 0.000
G62.9 Polyneuropathy, unspecified
0.735 0.265 0.000
Y83.9 Surgical procedure, unspecified
0.734 0.265 0.000
G30-G32 Other degenerative diseases of the nervous system
0.734 0.266 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.734 0.266 0.000
C79.2 Secondary malignant neoplasm of skin
0.733 0.267 0.000
I30 Acute pericarditis
0.731 0.269 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.730 0.270 0.000
Z88.0 Personal history of allergy to penicillin
0.729 0.271 0.000
M47 Spondylosis
0.728 0.272 0.000
Z89 Acquired absence of limb
0.727 0.272 0.000
Z35 Supervision of high-risk pregnancy
0.727 0.273 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.727 0.273 0.000
O60-O75 Complications of labour and delivery
0.726 0.274 0.000
Z31 Procreative management
0.725 0.275 0.000
H10-H13 Disorders of conjunctiva
0.723 0.277 0.000
C78.2 Secondary malignant neoplasm of pleura
0.723 0.277 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.723 0.277 0.000
H26 Other cataract
0.723 0.277 0.000
B35-B49 Mycoses
0.722 0.278 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.722 0.278 0.000
B95-B98 Bacterial, viral and other infectious agents
0.721 0.279 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.720 0.280 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.720 0.280 0.000
C92 Myeloid leukaemia
0.720 0.280 0.000
C77.0 Lymph nodes of head, face and neck
0.719 0.281 0.000
C79.6 Secondary malignant neoplasm of ovary
0.717 0.283 0.000
Y83.0 Surgical operation with transplant of whole organ
0.717 0.283 0.000
Y83.8 Other surgical procedures
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.717 0.283 0.000
D05 Carcinoma in situ of breast
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.285 0.000
Y10-Y34 Event of undetermined intent
0.714 0.285 0.000
Y00-Y09 Assault
0.714 0.285 0.000
X85-X99 Assault
0.714 0.285 0.000
X60-X84 Intentional self-harm
0.714 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.714 0.285 0.000
X50-X57 Overexertion, travel and privation
0.714 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.285 0.000
X30-X39 Exposure to forces of nature
0.714 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.285 0.000
X10-X19 Contact with heat and hot substances
0.714 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.285 0.000
W75-W84 Other accidental threats to breathing
0.714 0.285 0.000
W65-W74 Accidental drowning and submersion
0.714 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.285 0.000
V95-V97 Air and space transport accidents
0.714 0.285 0.000
V90-V94 Water transport accidents
0.714 0.285 0.000
V80-V89 Other land transport accidents
0.714 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.714 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.285 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.714 0.286 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.713 0.287 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.712 0.288 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.712 0.288 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.712 0.288 0.000
I50 Heart failure
0.711 0.289 0.000
Y83.5 Amputation of limb(s)
0.711 0.289 0.000
J18 Pneumonia, organism unspecified
0.711 0.289 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.710 0.290 0.000
I73 Other peripheral vascular diseases
0.710 0.290 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.709 0.291 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
H33 Retinal detachments and breaks
0.708 0.292 0.000
I33 Acute and subacute endocarditis
0.707 0.293 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.706 0.294 0.000
V10-V19 Pedal cyclist injured in transport accident
0.706 0.294 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.706 0.294 0.000
O97 Death from sequelae of direct obstetric causes
0.706 0.294 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.706 0.294 0.000
O95 Obstetric death of unspecified cause
0.706 0.294 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.706 0.294 0.000
H52.3 Anisometropia and aniseikonia
0.704 0.296 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.704 0.296 0.000
O30 Multiple gestation
0.703 0.296 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.703 0.297 0.000
Z13.1 Special screening examination for diabetes mellitus
0.702 0.298 0.000
E20-E35 Disorders of other endocrine glands
0.702 0.298 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.701 0.299 0.000
Z92.8 Personal history of other medical treatment
0.701 0.299 0.000
G61 Inflammatory polyneuropathy
0.701 0.299 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.700 0.300 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.699 0.301 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.698 0.301 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.698 0.301 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.698 0.301 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.698 0.301 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.698 0.301 0.000
H00 Hordeolum and chalazion
0.698 0.302 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.697 0.303 0.000
O32.2 Maternal care for transverse and oblique lie
0.696 0.304 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.696 0.304 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.696 0.304 0.000
Z38 Liveborn infants according to place of birth
0.694 0.306 0.000
Z32 Pregnancy examination and test
0.694 0.306 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.694 0.306 0.000
S50-S59 Injuries to the elbow and forearm
0.694 0.306 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.693 0.307 0.000
C95 Leukaemia of unspecified cell type
0.693 0.307 0.000
C94 Other leukaemias of specified cell type
0.693 0.307 0.000
C93 Monocytic leukaemia
0.693 0.307 0.000
C88 Malignant immunoproliferative diseases
0.693 0.307 0.000
C86 Other specified types of T/NK-cell lymphoma
0.693 0.307 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.693 0.307 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.693 0.307 0.000
I23 Certain current complications following acute myocardial infarction
0.692 0.308 0.000
O41 Other disorders of amniotic fluid and membranes
0.692 0.308 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.692 0.308 0.000
C81 Hodgkin's disease
0.692 0.308 0.000
Z92.9 Personal history of medical treatment, unspecified
0.692 0.308 0.000
Z92.5 Personal history of rehabilitation measures
0.692 0.308 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.309 0.000
I48 Atrial fibrillation and flutter
0.691 0.309 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.309 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.309 0.000
I40 Acute myocarditis
0.691 0.309 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.309 0.000
I37 Pulmonary valve disorders
0.691 0.309 0.000
I36 Nonrheumatic tricuspid valve disorders
0.691 0.309 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.309 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.690 0.310 0.000
H55-H59 Other disorders of eye and adnexa
0.690 0.310 0.000
Z30 Contraceptive management
0.689 0.311 0.000
I22 Subsequent myocardial infarction
0.689 0.311 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.689 0.311 0.000
H49 Paralytic strabismus
0.688 0.312 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.687 0.313 0.000
C64-C68 Malignant neoplasms of urinary tract
0.686 0.314 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.685 0.315 0.000
H05 Disorders of orbit
0.685 0.315 0.000
M86-M90 Other osteopathies
0.685 0.315 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.685 0.315 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.684 0.316 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.683 0.317 0.000
J18.1 Lobar pneumonia, unspecified
0.683 0.317 0.000
G20 Parkinson's disease
0.683 0.317 0.000
Z93.2 Ileostomy status
0.683 0.317 0.000
I35 Nonrheumatic aortic valve disorders
0.683 0.317 0.000
I47.0 Reentry ventricular arrhythmia
0.683 0.317 0.000
T33-T35 Frostbite
0.681 0.319 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.681 0.319 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.681 0.319 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.681 0.319 0.000
T00-T07 Injuries involving multiple body regions
0.681 0.319 0.000
O03 Spontaneous abortion
0.681 0.319 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.681 0.319 0.000
C18 Malignant neoplasm of colon
0.677 0.323 0.000
O42 Premature rupture of membranes
0.677 0.323 0.000
J90-J94 Other diseases of pleura
0.677 0.323 0.000
Y84.6 Urinary catheterisation
0.677 0.323 0.000
M23.8 Other internal derangements of knee
0.676 0.324 0.000
I38 Endocarditis, valve unspecified
0.676 0.324 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.676 0.324 0.000
Y40.9 Systemic antibiotic, unspecified
0.676 0.324 0.000
Chapter XIV Diseases of the genitourinary system
0.675 0.325 0.000
R76 Other abnormal immunological findings in serum
0.675 0.325 0.000
T79-T79 Certain early complications of trauma
0.674 0.326 0.000
Z99.8 Dependence on other enabling machines and devices
0.674 0.326 0.000
G50 Disorders of trigeminal nerve
0.674 0.326 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.674 0.326 0.000
Z50 Care involving use of rehabilitation procedures
0.673 0.327 0.000
Z36.5 Antenatal screening for isoimmunisation
0.670 0.330 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.670 0.330 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.670 0.330 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.670 0.330 0.000
R47 Speech disturbances, not elsewhere classified
0.670 0.330 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.668 0.332 0.000
H43-H45 Disorders of vitreous body and globe
0.668 0.332 0.000
I45 Other conduction disorders
0.668 0.332 0.000
T87 Complications peculiar to reattachment and amputation
0.667 0.333 0.000
T86 Failure and rejection of transplanted organs and tissues
0.667 0.333 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.667 0.333 0.000
H40 Glaucoma
0.667 0.333 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.667 0.333 0.000
O45 Premature separation of placenta [abruptio placentae]
0.666 0.334 0.000
O43 Placental disorders
0.666 0.334 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.666 0.334 0.000
O33 Maternal care for known or suspected disproportion
0.666 0.334 0.000
O31 Complications specific to multiple gestation
0.666 0.334 0.000
O40 Polyhydramnios
0.666 0.334 0.000
O00 Ectopic pregnancy
0.666 0.334 0.000
A49.0 Staphylococcal infection, unspecified
0.664 0.336 0.000
T81.9 Unspecified complication of procedure
0.664 0.336 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.664 0.336 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.664 0.336 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.664 0.336 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.664 0.336 0.000
S82 Fracture of lower leg, including ankle
0.664 0.336 0.000
H26.9 Cataract, unspecified
0.664 0.336 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.663 0.337 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.663 0.337 0.000
I44.6 Other and unspecified fascicular block
0.663 0.337 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.662 0.338 0.000
Z96.7 Presence of other bone and tendon implants
0.662 0.338 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.661 0.338 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.660 0.340 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.660 0.340 0.000
C85.0 Lymphosarcoma
0.660 0.340 0.000
B99-B99 Other infectious diseases
0.660 0.340 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.660 0.340 0.000
B65-B83 Helminthiases
0.660 0.340 0.000
B50-B64 Protozoal diseases
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.660 0.340 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.660 0.340 0.000
A80-A89 Viral infections of the central nervous system
0.660 0.340 0.000
A75-A79 Rickettsioses
0.660 0.340 0.000
A70-A74 Other diseases caused by chlamydiae
0.660 0.340 0.000
A65-A69 Other spirochaetal diseases
0.660 0.340 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.660 0.340 0.000
A20-A28 Certain zoonotic bacterial diseases
0.660 0.340 0.000
A15-A19 Tuberculosis
0.660 0.340 0.000
G24 Dystonia
0.659 0.341 0.000
O47 False labour
0.658 0.342 0.000
I73.9 Peripheral vascular disease, unspecified
0.658 0.342 0.000
Z85.6 Personal history of leukaemia
0.658 0.342 0.000
A46 Erysipelas
0.658 0.342 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.657 0.343 0.000
I71 Aortic aneurysm and dissection
0.657 0.343 0.000
C77.4 Inguinal and lower limb lymph nodes
0.656 0.343 0.000
H51 Other disorders of binocular movement
0.656 0.344 0.000
Q00-Q07 Congenital malformations of the nervous system
0.656 0.344 0.000
H33.0 Retinal detachment with retinal break
0.654 0.346 0.000
I25.6 Silent myocardial ischaemia
0.653 0.346 0.000
I25.4 Coronary artery aneurysm
0.653 0.346 0.000
I25.3 Aneurysm of heart
0.653 0.346 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.653 0.346 0.000
G44 Other headache syndromes
0.653 0.347 0.000
I99 Other and unspecified disorders of circulatory system
0.653 0.347 0.000
Y44 Agents primarily affecting blood constituents
0.653 0.347 0.000
I51 Complications and ill-defined descriptions of heart disease
0.651 0.348 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.651 0.349 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.651 0.349 0.000
D04 Carcinoma in situ of skin
0.651 0.349 0.000
E70-E90 Metabolic disorders
0.651 0.349 0.000
M47.2 Other spondylosis with radiculopathy
0.651 0.349 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.650 0.350 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.650 0.350 0.000
G60 Hereditary and idiopathic neuropathy
0.649 0.351 0.000
G64 Other disorders of peripheral nervous system
0.649 0.351 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.649 0.351 0.000
Z00.0 General medical examination
0.648 0.352 0.000
H04.1 Other disorders of lachrymal gland
0.647 0.353 0.000
C77.9 Lymph node, unspecified
0.647 0.353 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.646 0.354 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.646 0.354 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.646 0.354 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.646 0.354 0.000
Z93.1 Gastrostomy status
0.645 0.355 0.000
H53-H54 Visual disturbances and blindness
0.644 0.356 0.000
O84 Multiple delivery
0.644 0.356 0.000
O83 Other assisted single delivery
0.644 0.356 0.000
O81 Single delivery by forceps and vacuum extractor
0.644 0.356 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.644 0.356 0.000
C50-C50 Malignant neoplasm of breast
0.643 0.357 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.643 0.357 0.000
G41 Status epilepticus
0.643 0.357 0.000
R45 Symptoms and signs involving emotional state
0.643 0.357 0.000
H27 Other disorders of lens
0.643 0.357 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.642 0.358 0.000
M24 Other specific joint derangements
0.642 0.358 0.000
O36.9 Maternal care for foetal problem, unspecified
0.641 0.358 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.641 0.359 0.000
H01.0 Blepharitis
0.641 0.359 0.000
T78 Adverse effects, not elsewhere classified
0.641 0.359 0.000
Z39 Postpartum care and examination
0.640 0.359 0.000
C16 Malignant neoplasm of stomach
0.639 0.361 0.000
G96 Other disorders of central nervous system
0.639 0.361 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.638 0.362 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.637 0.363 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.637 0.363 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.636 0.363 0.000
I34 Nonrheumatic mitral valve disorders
0.636 0.364 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.636 0.364 0.000
M60-M63 Disorders of muscles
0.636 0.364 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.635 0.364 0.000
R41.0 Disorientation, unspecified
0.635 0.364 0.000
M40-M43 Deforming dorsopathies
0.635 0.365 0.000
G12 Spinal muscular atrophy and related syndromes
0.635 0.365 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.635 0.365 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.635 0.365 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.635 0.365 0.000
C17 Malignant neoplasm of small intestine
0.635 0.365 0.000
C23 Malignant neoplasm of gallbladder
0.635 0.365 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.635 0.365 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.635 0.365 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.635 0.365 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.635 0.365 0.000
N30-N39 Other diseases of urinary system
0.634 0.366 0.000
Y52 Agents primarily affecting the cardiovascular system
0.633 0.367 0.000
Z83.5 Family history of eye and ear disorders
0.633 0.367 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.633 0.367 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.632 0.368 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.632 0.368 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.631 0.369 0.000
Z95.0 Presence of cardiac pacemaker
0.631 0.369 0.000
H52.2 Astigmatism
0.631 0.369 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.631 0.369 0.000
I44.7 Left bundle-branch block, unspecified
0.630 0.370 0.000
O32.0 Maternal care for unstable lie
0.630 0.370 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.630 0.370 0.000
C62 Malignant neoplasm of testis
0.627 0.373 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.627 0.373 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.626 0.374 0.000
B15-B19 Viral hepatitis
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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